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Network neighborhood for query Sequence : IBP1_MOUSE

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IBP1_MOUSE
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IBP1_MOUSE
θ value	4.70271e-166 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP1_HUMAN
θ value	4.1872e-106 (rank : 2)	NC score	0.982076 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP4_HUMAN
θ value	8.89434e-40 (rank : 3)	NC score	0.918668 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
θ value	1.98146e-39 (rank : 4)	NC score	0.917393 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	55	Shared Neighborhood Hits	40
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP2_MOUSE
θ value	2.42216e-37 (rank : 5)	NC score	0.914044 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP2_HUMAN
θ value	3.4976e-36 (rank : 6)	NC score	0.913710 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	49
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP5_HUMAN
θ value	6.59618e-35 (rank : 7)	NC score	0.904623 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	1.46948e-34 (rank : 8)	NC score	0.903815 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP3_HUMAN
θ value	5.77852e-31 (rank : 9)	NC score	0.896221 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_MOUSE
θ value	4.14116e-29 (rank : 10)	NC score	0.885102 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP6_HUMAN
θ value	1.47631e-18 (rank : 11)	NC score	0.839644 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
θ value	3.40345e-15 (rank : 12)	NC score	0.826219 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

HTRA1_HUMAN
θ value	5.26297e-08 (rank : 13)	NC score	0.349144 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	155	Shared Neighborhood Hits	44
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HTRA1_MOUSE
θ value	2.21117e-06 (rank : 14)	NC score	0.339042 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	140	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

SMOC2_MOUSE
θ value	8.40245e-06 (rank : 15)	NC score	0.379833 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

SMOC2_HUMAN
θ value	7.1131e-05 (rank : 16)	NC score	0.374843 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

IBP7_MOUSE
θ value	9.29e-05 (rank : 17)	NC score	0.256872 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	230	Shared Neighborhood Hits	29
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

THYG_MOUSE
θ value	9.29e-05 (rank : 18)	NC score	0.213767 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	161	Shared Neighborhood Hits	33
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

TICN2_HUMAN
θ value	0.000121331 (rank : 19)	NC score	0.379598 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	34
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

THYG_HUMAN
θ value	0.000158464 (rank : 20)	NC score	0.227822 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	154	Shared Neighborhood Hits	36
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TICN1_MOUSE
θ value	0.000461057 (rank : 21)	NC score	0.382433 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	79	Shared Neighborhood Hits	36
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_HUMAN
θ value	0.000602161 (rank : 22)	NC score	0.380532 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

HG2A_MOUSE
θ value	0.00228821 (rank : 23)	NC score	0.380054 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

IBP7_HUMAN
θ value	0.00228821 (rank : 24)	NC score	0.255629 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	220	Shared Neighborhood Hits	30
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

HG2A_HUMAN
θ value	0.00298849 (rank : 25)	NC score	0.346452 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

SMOC1_HUMAN
θ value	0.00298849 (rank : 26)	NC score	0.349846 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

SMOC1_MOUSE
θ value	0.00390308 (rank : 27)	NC score	0.350417 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

TICN2_MOUSE
θ value	0.00390308 (rank : 28)	NC score	0.376294 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

NOTC3_HUMAN
θ value	0.00869519 (rank : 29)	NC score	0.027519 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	1062	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TICN3_HUMAN
θ value	0.00869519 (rank : 30)	NC score	0.353041 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

NID2_HUMAN
θ value	0.0113563 (rank : 31)	NC score	0.149760 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	456	Shared Neighborhood Hits	38
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

WISP2_HUMAN
θ value	0.0113563 (rank : 32)	NC score	0.202412 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

MCSP_MOUSE
θ value	0.0193708 (rank : 33)	NC score	0.077956 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

GSCL_HUMAN
θ value	0.0330416 (rank : 34)	NC score	0.023342 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	O15499	Gene names	GSCL
Domain Architecture
Description	Homeobox protein goosecoid-like (GSC-2).

TICN3_MOUSE
θ value	0.0431538 (rank : 35)	NC score	0.346390 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

CRIM1_HUMAN
θ value	0.125558 (rank : 36)	NC score	0.141521 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	362	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KAZD1_MOUSE
θ value	0.125558 (rank : 37)	NC score	0.224861 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	281	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

LCE2D_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.112299 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

WISP2_MOUSE
θ value	0.125558 (rank : 39)	NC score	0.164022 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

ZN639_HUMAN
θ value	0.125558 (rank : 40)	NC score	0.004930 (rank : 114)
Query Neighborhood Hits	97	Target Neighborhood Hits	723	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UID6	Gene names	ZNF639, ZASC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 639 (Zinc finger protein ZASC1) (Zinc finger protein ANC_2H01).

KAZD1_HUMAN
θ value	0.21417 (rank : 41)	NC score	0.220726 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	248	Shared Neighborhood Hits	40
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

RRMJ3_MOUSE
θ value	0.279714 (rank : 42)	NC score	0.043954 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

HTRA3_MOUSE
θ value	0.365318 (rank : 43)	NC score	0.202340 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	156	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA3_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.201438 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

ESM1_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.244929 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

HTRA4_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.176540 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

NID2_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.146473 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	338	Shared Neighborhood Hits	40
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOV_HUMAN
θ value	0.62314 (rank : 48)	NC score	0.142155 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

TRIM7_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.008100 (rank : 110)
Query Neighborhood Hits	97	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

LCE2C_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.090901 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

NOV_MOUSE
θ value	0.813845 (rank : 51)	NC score	0.134578 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	130	Shared Neighborhood Hits	31
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

PHX2B_HUMAN
θ value	0.813845 (rank : 52)	NC score	0.014406 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.014406 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

WISP1_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.093165 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

KR103_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.032025 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	212	Shared Neighborhood Hits	20
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

MGR4_HUMAN
θ value	1.06291 (rank : 56)	NC score	0.014928 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

AMOT_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.012805 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	712	Shared Neighborhood Hits	6
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

IGHG3_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.010228 (rank : 106)
Query Neighborhood Hits	97	Target Neighborhood Hits	234	Shared Neighborhood Hits	3
SwissProt Accessions	P01860	Gene names	IGHG3
Domain Architecture
Description	Ig gamma-3 chain C region (Heavy chain disease protein) (HDC).

NID1_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.134528 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	329	Shared Neighborhood Hits	36
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

BRE1B_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.005611 (rank : 112)
Query Neighborhood Hits	97	Target Neighborhood Hits	970	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

CE290_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.002235 (rank : 116)
Query Neighborhood Hits	97	Target Neighborhood Hits	1553	Shared Neighborhood Hits	5
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

ESM1_MOUSE
θ value	2.36792 (rank : 62)	NC score	0.240439 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

MEGF6_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.029762 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TXD11_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.019690 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

CTGF_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.154986 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

GRN_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.034723 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

K1802_MOUSE
θ value	3.0926 (rank : 67)	NC score	0.004175 (rank : 115)
Query Neighborhood Hits	97	Target Neighborhood Hits	1596	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RRMJ3_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.037251 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IY81, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6	Gene names	FTSJ3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

TAF4_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.013679 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	687	Shared Neighborhood Hits	7
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

DLL3_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.020656 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

TNR14_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.020939 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	149	Shared Neighborhood Hits	14
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

WISP3_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.121985 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ABI2_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.005568 (rank : 113)
Query Neighborhood Hits	97	Target Neighborhood Hits	350	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

CABL1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.012117 (rank : 104)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

CELR3_HUMAN
θ value	5.27518 (rank : 75)	NC score	0.005738 (rank : 111)
Query Neighborhood Hits	97	Target Neighborhood Hits	680	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CXXC6_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.018240 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

DMPK_HUMAN
θ value	5.27518 (rank : 77)	NC score	-0.002901 (rank : 119)
Query Neighborhood Hits	97	Target Neighborhood Hits	944	Shared Neighborhood Hits	2
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

EDA_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.009684 (rank : 107)
Query Neighborhood Hits	97	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

NOTC3_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.019941 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RNF31_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.011963 (rank : 105)
Query Neighborhood Hits	97	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

XPC_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.014426 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

ZBTB5_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.001252 (rank : 117)
Query Neighborhood Hits	97	Target Neighborhood Hits	811	Shared Neighborhood Hits	5
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

ZBTB5_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.001210 (rank : 118)
Query Neighborhood Hits	97	Target Neighborhood Hits	801	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

ZNHI4_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.017330 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

I10R2_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.015485 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

LTBP4_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.018896 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	607	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MGR6_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.012353 (rank : 103)
Query Neighborhood Hits	97	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.012425 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

WISP1_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.089415 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	123	Shared Neighborhood Hits	30
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ADA11_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.008413 (rank : 108)
Query Neighborhood Hits	97	Target Neighborhood Hits	259	Shared Neighborhood Hits	14
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.008332 (rank : 109)
Query Neighborhood Hits	97	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

CTGF_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.109392 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	124	Shared Neighborhood Hits	36
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

I10R2_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.014215 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

LCE1B_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.109804 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE4A_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.207713 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

MUC5B_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.019354 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	1020	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SSPO_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.021512 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	800	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

AGRIN_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.052029 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	582	Shared Neighborhood Hits	42
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CYR61_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.129767 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.129947 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

FSTL1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.051893 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

FSTL1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.051977 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL3_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.070975 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.066505 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	152	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FST_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.058513 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.056725 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

HTRA2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.094363 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.094675 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

LCE1C_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.094624 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.095572 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.087865 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

NID1_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.122672 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SPRC_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.064570 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.063200 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRL1_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.054302 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

TACD1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.206747 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

TACD2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.178327 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

TEFF2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.054327 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.055168 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

Hits sorted by NC score

IBP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	4.70271e-166 (rank : 1)
Query Neighborhood Hits	97	Target Neighborhood Hits	97	Shared Neighborhood Hits	97
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP1_HUMAN
NC score	0.982076 (rank : 2)	θ value	4.1872e-106 (rank : 2)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	52
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IBP4_HUMAN
NC score	0.918668 (rank : 3)	θ value	8.89434e-40 (rank : 3)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	40
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP4_MOUSE
NC score	0.917393 (rank : 4)	θ value	1.98146e-39 (rank : 4)
Query Neighborhood Hits	97	Target Neighborhood Hits	55	Shared Neighborhood Hits	40
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

IBP2_MOUSE
NC score	0.914044 (rank : 5)	θ value	2.42216e-37 (rank : 5)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	49
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP2_HUMAN
NC score	0.913710 (rank : 6)	θ value	3.4976e-36 (rank : 6)
Query Neighborhood Hits	97	Target Neighborhood Hits	61	Shared Neighborhood Hits	49
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

IBP5_HUMAN
NC score	0.904623 (rank : 7)	θ value	6.59618e-35 (rank : 7)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
NC score	0.903815 (rank : 8)	θ value	1.46948e-34 (rank : 8)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	51
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP3_HUMAN
NC score	0.896221 (rank : 9)	θ value	5.77852e-31 (rank : 9)
Query Neighborhood Hits	97	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP3_MOUSE
NC score	0.885102 (rank : 10)	θ value	4.14116e-29 (rank : 10)
Query Neighborhood Hits	97	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP6_HUMAN
NC score	0.839644 (rank : 11)	θ value	1.47631e-18 (rank : 11)
Query Neighborhood Hits	97	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
NC score	0.826219 (rank : 12)	θ value	3.40345e-15 (rank : 12)
Query Neighborhood Hits	97	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

TICN1_MOUSE
NC score	0.382433 (rank : 13)	θ value	0.000461057 (rank : 21)
Query Neighborhood Hits	97	Target Neighborhood Hits	79	Shared Neighborhood Hits	36
SwissProt Accessions	Q62288	Gene names	Spock1, Spock, Ticn1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

TICN1_HUMAN
NC score	0.380532 (rank : 14)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	97	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q08629	Gene names	SPOCK1, SPOCK, TIC1, TICN1
Domain Architecture
Description	Testican-1 precursor (Protein SPOCK).

HG2A_MOUSE
NC score	0.380054 (rank : 15)	θ value	0.00228821 (rank : 23)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	P04441, O19452	Gene names	Cd74, Ii
Domain Architecture
Description	H-2 class II histocompatibility antigen gamma chain (MHC class II- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD74 antigen).

SMOC2_MOUSE
NC score	0.379833 (rank : 16)	θ value	8.40245e-06 (rank : 15)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	32
SwissProt Accessions	Q8CD91, Q8VCM1, Q9D9K2, Q9ER95	Gene names	Smoc2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2).

TICN2_HUMAN
NC score	0.379598 (rank : 17)	θ value	0.000121331 (rank : 19)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	34
SwissProt Accessions	Q92563, Q6UW87	Gene names	SPOCK2, KIAA0275, TICN2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

TICN2_MOUSE
NC score	0.376294 (rank : 18)	θ value	0.00390308 (rank : 28)
Query Neighborhood Hits	97	Target Neighborhood Hits	69	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ER58	Gene names	Spock2, Ticn2
Domain Architecture
Description	Testican-2 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2).

SMOC2_HUMAN
NC score	0.374843 (rank : 19)	θ value	7.1131e-05 (rank : 16)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H3U7, Q5TAT7, Q5TAT8, Q86VV9, Q96SF3, Q9H1L3, Q9H1L4, Q9H3U0, Q9H4F7, Q9HCV2	Gene names	SMOC2, SMAP2
Domain Architecture
Description	SPARC-related modular calcium-binding protein 2 precursor (Secreted modular calcium-binding protein 2) (SMOC-2) (Smooth muscle-associated protein 2) (SMAP-2).

TICN3_HUMAN
NC score	0.353041 (rank : 20)	θ value	0.00869519 (rank : 30)
Query Neighborhood Hits	97	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BQ16, O75705, Q6UW53, Q96Q26	Gene names	SPOCK3, TICN3
Domain Architecture
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

SMOC1_MOUSE
NC score	0.350417 (rank : 21)	θ value	0.00390308 (rank : 27)
Query Neighborhood Hits	97	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLY1, Q9WVN9	Gene names	Smoc1, Srg
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1) (SPARC-related gene protein).

SMOC1_HUMAN
NC score	0.349846 (rank : 22)	θ value	0.00298849 (rank : 26)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	33
SwissProt Accessions	Q9H4F8, Q96F78	Gene names	SMOC1
Domain Architecture
Description	SPARC-related modular calcium-binding protein 1 precursor (Secreted modular calcium-binding protein 1) (SMOC-1).

HTRA1_HUMAN
NC score	0.349144 (rank : 23)	θ value	5.26297e-08 (rank : 13)
Query Neighborhood Hits	97	Target Neighborhood Hits	155	Shared Neighborhood Hits	44
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

HG2A_HUMAN
NC score	0.346452 (rank : 24)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	97	Target Neighborhood Hits	36	Shared Neighborhood Hits	29
SwissProt Accessions	P04233, Q14597, Q29832, Q5U0J8, Q8WLP6	Gene names	CD74, DHLAG
Domain Architecture	No domain graphic available
Description	HLA class II histocompatibility antigen gamma chain (HLA-DR antigens- associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (p33) (CD74 antigen).

TICN3_MOUSE
NC score	0.346390 (rank : 25)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	97	Target Neighborhood Hits	83	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BKV0, Q9ER59	Gene names	Spock3
Domain Architecture	No domain graphic available
Description	Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3).

HTRA1_MOUSE
NC score	0.339042 (rank : 26)	θ value	2.21117e-06 (rank : 14)
Query Neighborhood Hits	97	Target Neighborhood Hits	140	Shared Neighborhood Hits	48
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

IBP7_MOUSE
NC score	0.256872 (rank : 27)	θ value	9.29e-05 (rank : 17)
Query Neighborhood Hits	97	Target Neighborhood Hits	230	Shared Neighborhood Hits	29
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IBP7_HUMAN
NC score	0.255629 (rank : 28)	θ value	0.00228821 (rank : 24)
Query Neighborhood Hits	97	Target Neighborhood Hits	220	Shared Neighborhood Hits	30
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

ESM1_HUMAN
NC score	0.244929 (rank : 29)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	97	Target Neighborhood Hits	110	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
NC score	0.240439 (rank : 30)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	97	Target Neighborhood Hits	107	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

THYG_HUMAN
NC score	0.227822 (rank : 31)	θ value	0.000158464 (rank : 20)
Query Neighborhood Hits	97	Target Neighborhood Hits	154	Shared Neighborhood Hits	36
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

KAZD1_MOUSE
NC score	0.224861 (rank : 32)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	97	Target Neighborhood Hits	281	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KAZD1_HUMAN
NC score	0.220726 (rank : 33)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	97	Target Neighborhood Hits	248	Shared Neighborhood Hits	40
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

THYG_MOUSE
NC score	0.213767 (rank : 34)	θ value	9.29e-05 (rank : 18)
Query Neighborhood Hits	97	Target Neighborhood Hits	161	Shared Neighborhood Hits	33
SwissProt Accessions	O08710, O88590, Q9QWY7	Gene names	Tg, Tgn
Domain Architecture
Description	Thyroglobulin precursor.

LCE4A_HUMAN
NC score	0.207713 (rank : 35)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	97	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

TACD1_HUMAN
NC score	0.206747 (rank : 36)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	97	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	P16422, P18180, Q96C47	Gene names	TACSTD1, GA733-2, M1S2, TROP1
Domain Architecture
Description	Tumor-associated calcium signal transducer 1 precursor (Major gastrointestinal tumor-associated protein GA733-2) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Adenocarcinoma- associated antigen) (KSA) (KS 1/4 antigen) (Cell surface glycoprotein Trop-1) (CD326 antigen).

WISP2_HUMAN
NC score	0.202412 (rank : 37)	θ value	0.0113563 (rank : 32)
Query Neighborhood Hits	97	Target Neighborhood Hits	126	Shared Neighborhood Hits	36
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

HTRA3_MOUSE
NC score	0.202340 (rank : 38)	θ value	0.365318 (rank : 43)
Query Neighborhood Hits	97	Target Neighborhood Hits	156	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

HTRA3_HUMAN
NC score	0.201438 (rank : 39)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	97	Target Neighborhood Hits	152	Shared Neighborhood Hits	38
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

TACD2_HUMAN
NC score	0.178327 (rank : 40)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	97	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	P09758, Q15658, Q96QD2	Gene names	TACSTD2, GA733-1, M1S1, TROP2
Domain Architecture
Description	Tumor-associated calcium signal transducer 2 precursor (Pancreatic carcinoma marker protein GA733-1) (Cell surface glycoprotein Trop-2).

HTRA4_HUMAN
NC score	0.176540 (rank : 41)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	97	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

WISP2_MOUSE
NC score	0.164022 (rank : 42)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	97	Target Neighborhood Hits	129	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

CTGF_HUMAN
NC score	0.154986 (rank : 43)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	97	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

NID2_HUMAN
NC score	0.149760 (rank : 44)	θ value	0.0113563 (rank : 31)
Query Neighborhood Hits	97	Target Neighborhood Hits	456	Shared Neighborhood Hits	38
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NID2_MOUSE
NC score	0.146473 (rank : 45)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	97	Target Neighborhood Hits	338	Shared Neighborhood Hits	40
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NOV_HUMAN
NC score	0.142155 (rank : 46)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	97	Target Neighborhood Hits	128	Shared Neighborhood Hits	34
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

CRIM1_HUMAN
NC score	0.141521 (rank : 47)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	97	Target Neighborhood Hits	362	Shared Neighborhood Hits	44
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

NOV_MOUSE
NC score	0.134578 (rank : 48)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	97	Target Neighborhood Hits	130	Shared Neighborhood Hits	31
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NID1_HUMAN
NC score	0.134528 (rank : 49)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	97	Target Neighborhood Hits	329	Shared Neighborhood Hits	36
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

CYR61_MOUSE
NC score	0.129947 (rank : 50)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	97	Target Neighborhood Hits	156	Shared Neighborhood Hits	35
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

CYR61_HUMAN
NC score	0.129767 (rank : 51)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	97	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

NID1_MOUSE
NC score	0.122672 (rank : 52)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	97	Target Neighborhood Hits	335	Shared Neighborhood Hits	35
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

WISP3_HUMAN
NC score	0.121985 (rank : 53)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	97	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

LCE2D_HUMAN
NC score	0.112299 (rank : 54)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	97	Target Neighborhood Hits	50	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE1B_HUMAN
NC score	0.109804 (rank : 55)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	97	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

CTGF_MOUSE
NC score	0.109392 (rank : 56)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	97	Target Neighborhood Hits	124	Shared Neighborhood Hits	36
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

LCE1D_HUMAN
NC score	0.095572 (rank : 57)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	97	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

HTRA2_MOUSE
NC score	0.094675 (rank : 58)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	97	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

LCE1C_HUMAN
NC score	0.094624 (rank : 59)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	97	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

HTRA2_HUMAN
NC score	0.094363 (rank : 60)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	97	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

WISP1_HUMAN
NC score	0.093165 (rank : 61)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	97	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

LCE2C_HUMAN
NC score	0.090901 (rank : 62)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	97	Target Neighborhood Hits	53	Shared Neighborhood Hits	12
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

WISP1_MOUSE
NC score	0.089415 (rank : 63)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	97	Target Neighborhood Hits	123	Shared Neighborhood Hits	30
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

LCE1E_HUMAN
NC score	0.087865 (rank : 64)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	97	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

MCSP_MOUSE
NC score	0.077956 (rank : 65)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	97	Target Neighborhood Hits	108	Shared Neighborhood Hits	13
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

FSTL3_HUMAN
NC score	0.070975 (rank : 66)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	97	Target Neighborhood Hits	162	Shared Neighborhood Hits	25
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
NC score	0.066505 (rank : 67)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	97	Target Neighborhood Hits	152	Shared Neighborhood Hits	28
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

SPRC_HUMAN
NC score	0.064570 (rank : 68)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	97	Target Neighborhood Hits	45	Shared Neighborhood Hits	12
SwissProt Accessions	P09486	Gene names	SPARC, ON
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

SPRC_MOUSE
NC score	0.063200 (rank : 69)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	97	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	P07214	Gene names	Sparc
Domain Architecture
Description	SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40).

FST_HUMAN
NC score	0.058513 (rank : 70)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	97	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
NC score	0.056725 (rank : 71)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	97	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

TEFF2_MOUSE
NC score	0.055168 (rank : 72)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	97	Target Neighborhood Hits	214	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TEFF2_HUMAN
NC score	0.054327 (rank : 73)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	97	Target Neighborhood Hits	211	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

SPRL1_HUMAN
NC score	0.054302 (rank : 74)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	97	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

AGRIN_HUMAN
NC score	0.052029 (rank : 75)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	97	Target Neighborhood Hits	582	Shared Neighborhood Hits	42
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

FSTL1_MOUSE
NC score	0.051977 (rank : 76)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	97	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FSTL1_HUMAN
NC score	0.051893 (rank : 77)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	97	Target Neighborhood Hits	68	Shared Neighborhood Hits	19
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

RRMJ3_MOUSE
NC score	0.043954 (rank : 78)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	97	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

RRMJ3_HUMAN
NC score	0.037251 (rank : 79)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	97	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IY81, Q8N3A3, Q8WXX1, Q9BWM4, Q9NXT6	Gene names	FTSJ3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

GRN_MOUSE
NC score	0.034723 (rank : 80)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	97	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR103_HUMAN
NC score	0.032025 (rank : 81)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	97	Target Neighborhood Hits	212	Shared Neighborhood Hits	20
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

MEGF6_HUMAN
NC score	0.029762 (rank : 82)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	97	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NOTC3_HUMAN
NC score	0.027519 (rank : 83)	θ value	0.00869519 (rank : 29)
Query Neighborhood Hits	97	Target Neighborhood Hits	1062	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

GSCL_HUMAN
NC score	0.023342 (rank : 84)	θ value	0.0330416 (rank : 34)
Query Neighborhood Hits	97	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	O15499	Gene names	GSCL
Domain Architecture
Description	Homeobox protein goosecoid-like (GSC-2).

SSPO_MOUSE
NC score	0.021512 (rank : 85)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	97	Target Neighborhood Hits	800	Shared Neighborhood Hits	37
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR14_HUMAN
NC score	0.020939 (rank : 86)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	97	Target Neighborhood Hits	149	Shared Neighborhood Hits	14
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

DLL3_HUMAN
NC score	0.020656 (rank : 87)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	97	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

NOTC3_MOUSE
NC score	0.019941 (rank : 88)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	97	Target Neighborhood Hits	975	Shared Neighborhood Hits	27
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TXD11_MOUSE
NC score	0.019690 (rank : 89)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	97	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

MUC5B_HUMAN
NC score	0.019354 (rank : 90)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	97	Target Neighborhood Hits	1020	Shared Neighborhood Hits	31
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LTBP4_MOUSE
NC score	0.018896 (rank : 91)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	97	Target Neighborhood Hits	607	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CXXC6_HUMAN
NC score	0.018240 (rank : 92)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	97	Target Neighborhood Hits	180	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

ZNHI4_MOUSE
NC score	0.017330 (rank : 93)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	97	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q99PT3, Q9CY38	Gene names	Znhit4, Hmga1l4, Papa1
Domain Architecture	No domain graphic available
Description	Zinc finger HIT domain-containing protein 4 (PAP-1-associated protein 1) (PAPA-1) (High mobility group AT-hook 1-like 4).

I10R2_MOUSE
NC score	0.015485 (rank : 94)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	97	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

MGR4_HUMAN
NC score	0.014928 (rank : 95)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	97	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

XPC_MOUSE
NC score	0.014426 (rank : 96)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	97	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

PHX2B_HUMAN
NC score	0.014406 (rank : 97)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	97	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.014406 (rank : 98)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	97	Target Neighborhood Hits	407	Shared Neighborhood Hits	5
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

I10R2_HUMAN
NC score	0.014215 (rank : 99)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	97	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q08334, Q9BUU4	Gene names	IL10RB, CRFB4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

TAF4_HUMAN
NC score	0.013679 (rank : 100)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	97	Target Neighborhood Hits	687	Shared Neighborhood Hits	7
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

AMOT_HUMAN
NC score	0.012805 (rank : 101)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	97	Target Neighborhood Hits	712	Shared Neighborhood Hits	6
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

MGR6_MOUSE
NC score	0.012425 (rank : 102)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	97	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_HUMAN
NC score	0.012353 (rank : 103)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	97	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

CABL1_HUMAN
NC score	0.012117 (rank : 104)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	97	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

RNF31_HUMAN
NC score	0.011963 (rank : 105)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	97	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

IGHG3_HUMAN
NC score	0.010228 (rank : 106)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	97	Target Neighborhood Hits	234	Shared Neighborhood Hits	3
SwissProt Accessions	P01860	Gene names	IGHG3
Domain Architecture
Description	Ig gamma-3 chain C region (Heavy chain disease protein) (HDC).

EDA_MOUSE
NC score	0.009684 (rank : 107)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	97	Target Neighborhood Hits	141	Shared Neighborhood Hits	2
SwissProt Accessions	O54693, O35705, Q9QWJ8, Q9QZ01, Q9QZ02	Gene names	Eda, Ed1, Ta
Domain Architecture
Description	Ectodysplasin-A (EDA protein homolog) (Tabby protein) [Contains: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form].

ADA11_HUMAN
NC score	0.008413 (rank : 108)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	97	Target Neighborhood Hits	259	Shared Neighborhood Hits	14
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
NC score	0.008332 (rank : 109)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	97	Target Neighborhood Hits	263	Shared Neighborhood Hits	14
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

TRIM7_HUMAN
NC score	0.008100 (rank : 110)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	97	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

CELR3_HUMAN
NC score	0.005738 (rank : 111)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	97	Target Neighborhood Hits	680	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

BRE1B_MOUSE
NC score	0.005611 (rank : 112)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	97	Target Neighborhood Hits	970	Shared Neighborhood Hits	5
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

ABI2_HUMAN
NC score	0.005568 (rank : 113)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	97	Target Neighborhood Hits	350	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ZN639_HUMAN
NC score	0.004930 (rank : 114)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	97	Target Neighborhood Hits	723	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UID6	Gene names	ZNF639, ZASC1
Domain Architecture	No domain graphic available
Description	Zinc finger protein 639 (Zinc finger protein ZASC1) (Zinc finger protein ANC_2H01).

K1802_MOUSE
NC score	0.004175 (rank : 115)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	97	Target Neighborhood Hits	1596	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CE290_HUMAN
NC score	0.002235 (rank : 116)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	97	Target Neighborhood Hits	1553	Shared Neighborhood Hits	5
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

ZBTB5_HUMAN
NC score	0.001252 (rank : 117)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	97	Target Neighborhood Hits	811	Shared Neighborhood Hits	5
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

ZBTB5_MOUSE
NC score	0.001210 (rank : 118)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	97	Target Neighborhood Hits	801	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

DMPK_HUMAN
NC score	-0.002901 (rank : 119)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	97	Target Neighborhood Hits	944	Shared Neighborhood Hits	2
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).