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Network neighborhood for query Sequence : TXD11_MOUSE

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TXD11_MOUSE
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TXD11_HUMAN
θ value	0 (rank : 1)	NC score	0.859562 (rank : 2)
Query Neighborhood Hits	81	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TXD11_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

PDIA3_MOUSE
θ value	5.62301e-10 (rank : 3)	NC score	0.421889 (rank : 3)
Query Neighborhood Hits	81	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA3_HUMAN
θ value	3.64472e-09 (rank : 4)	NC score	0.417199 (rank : 4)
Query Neighborhood Hits	81	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

PDIA4_HUMAN
θ value	6.87365e-08 (rank : 5)	NC score	0.390190 (rank : 5)
Query Neighborhood Hits	81	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA4_MOUSE
θ value	1.29631e-06 (rank : 6)	NC score	0.380424 (rank : 6)
Query Neighborhood Hits	81	Target Neighborhood Hits	57	Shared Neighborhood Hits	26
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA1_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.343049 (rank : 8)
Query Neighborhood Hits	81	Target Neighborhood Hits	56	Shared Neighborhood Hits	26
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

PDIA1_MOUSE
θ value	0.000461057 (rank : 8)	NC score	0.339444 (rank : 9)
Query Neighborhood Hits	81	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA2_HUMAN
θ value	0.00298849 (rank : 9)	NC score	0.343667 (rank : 7)
Query Neighborhood Hits	81	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA6_MOUSE
θ value	0.00665767 (rank : 10)	NC score	0.313619 (rank : 10)
Query Neighborhood Hits	81	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

CP135_MOUSE
θ value	0.0148317 (rank : 11)	NC score	0.066228 (rank : 44)
Query Neighborhood Hits	81	Target Neighborhood Hits	1278	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

PDIA6_HUMAN
θ value	0.0193708 (rank : 12)	NC score	0.307022 (rank : 11)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

TXND4_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.283322 (rank : 13)
Query Neighborhood Hits	81	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA5_MOUSE
θ value	0.0252991 (rank : 14)	NC score	0.288263 (rank : 12)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXND5_MOUSE
θ value	0.0431538 (rank : 15)	NC score	0.282748 (rank : 14)
Query Neighborhood Hits	81	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND4_MOUSE
θ value	0.0736092 (rank : 16)	NC score	0.278872 (rank : 15)
Query Neighborhood Hits	81	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA5_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.278449 (rank : 16)
Query Neighborhood Hits	81	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXND3_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.118916 (rank : 28)
Query Neighborhood Hits	81	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

A16L1_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.035102 (rank : 97)
Query Neighborhood Hits	81	Target Neighborhood Hits	664	Shared Neighborhood Hits	24
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

KI21A_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.035873 (rank : 96)
Query Neighborhood Hits	81	Target Neighborhood Hits	1317	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

TXND1_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.244529 (rank : 18)
Query Neighborhood Hits	81	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3N1, Q8N487, Q8NBN5, Q9Y4T6	Gene names	TXNDC1, TMX, TXNDC
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor (Transmembrane Trx- related protein) (Thioredoxin-related transmembrane protein).

EP15R_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.054415 (rank : 71)
Query Neighborhood Hits	81	Target Neighborhood Hits	1135	Shared Neighborhood Hits	44
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

MRCKB_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.032839 (rank : 98)
Query Neighborhood Hits	81	Target Neighborhood Hits	2239	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ADIP_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.082243 (rank : 38)
Query Neighborhood Hits	81	Target Neighborhood Hits	470	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

KI21A_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.044045 (rank : 93)
Query Neighborhood Hits	81	Target Neighborhood Hits	1543	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

CCD41_MOUSE
θ value	0.365318 (rank : 26)	NC score	0.051311 (rank : 83)
Query Neighborhood Hits	81	Target Neighborhood Hits	1399	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

MYOC_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.059960 (rank : 53)
Query Neighborhood Hits	81	Target Neighborhood Hits	489	Shared Neighborhood Hits	25
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

K2C1B_MOUSE
θ value	0.47712 (rank : 28)	NC score	0.057516 (rank : 57)
Query Neighborhood Hits	81	Target Neighborhood Hits	503	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

K2C6B_MOUSE
θ value	0.47712 (rank : 29)	NC score	0.055035 (rank : 68)
Query Neighborhood Hits	81	Target Neighborhood Hits	506	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

TXD10_MOUSE
θ value	0.47712 (rank : 30)	NC score	0.243612 (rank : 19)
Query Neighborhood Hits	81	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXZ1, Q3US84, Q6PGA1, Q6ZPH5, Q8BZB8	Gene names	Txndc10, Kiaa1830
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10).

ADIP_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.084845 (rank : 36)
Query Neighborhood Hits	81	Target Neighborhood Hits	415	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

CASP_HUMAN
θ value	0.62314 (rank : 32)	NC score	0.066610 (rank : 43)
Query Neighborhood Hits	81	Target Neighborhood Hits	1131	Shared Neighborhood Hits	41
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.068142 (rank : 39)
Query Neighborhood Hits	81	Target Neighborhood Hits	1152	Shared Neighborhood Hits	42
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.065202 (rank : 45)
Query Neighborhood Hits	81	Target Neighborhood Hits	1574	Shared Neighborhood Hits	41
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	0.62314 (rank : 35)	NC score	0.067423 (rank : 41)
Query Neighborhood Hits	81	Target Neighborhood Hits	1620	Shared Neighborhood Hits	41
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TXND5_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.272934 (rank : 17)
Query Neighborhood Hits	81	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

CP135_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.056403 (rank : 62)
Query Neighborhood Hits	81	Target Neighborhood Hits	1290	Shared Neighborhood Hits	43
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

K2C6A_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.055797 (rank : 65)
Query Neighborhood Hits	81	Target Neighborhood Hits	505	Shared Neighborhood Hits	36
SwissProt Accessions	P02538, Q6NT67, Q96CL4	Gene names	KRT6A, K6A
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin).

K2C6A_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.053783 (rank : 72)
Query Neighborhood Hits	81	Target Neighborhood Hits	481	Shared Neighborhood Hits	33
SwissProt Accessions	P50446, Q9Z332	Gene names	Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin) (Keratin-6 alpha) (mK6-alpha).

K2C6B_HUMAN
θ value	0.813845 (rank : 40)	NC score	0.056552 (rank : 60)
Query Neighborhood Hits	81	Target Neighborhood Hits	526	Shared Neighborhood Hits	35
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

K2C6C_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.055907 (rank : 64)
Query Neighborhood Hits	81	Target Neighborhood Hits	503	Shared Neighborhood Hits	36
SwissProt Accessions	P48666	Gene names	KRT6C
Domain Architecture
Description	Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin).

K2C6E_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.056768 (rank : 59)
Query Neighborhood Hits	81	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

RABE2_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.058745 (rank : 55)
Query Neighborhood Hits	81	Target Neighborhood Hits	598	Shared Neighborhood Hits	34
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

TRAIP_MOUSE
θ value	0.813845 (rank : 44)	NC score	0.060633 (rank : 52)
Query Neighborhood Hits	81	Target Neighborhood Hits	745	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

TXND1_MOUSE
θ value	0.813845 (rank : 45)	NC score	0.223433 (rank : 21)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VBT0, Q3UCI8, Q9CSD5	Gene names	Txndc1, Txndc
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor.

TXND3_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.084248 (rank : 37)
Query Neighborhood Hits	81	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

CING_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.056454 (rank : 61)
Query Neighborhood Hits	81	Target Neighborhood Hits	1275	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

FYCO1_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.061030 (rank : 49)
Query Neighborhood Hits	81	Target Neighborhood Hits	1149	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.060875 (rank : 51)
Query Neighborhood Hits	81	Target Neighborhood Hits	1059	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

LZTS1_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.066666 (rank : 42)
Query Neighborhood Hits	81	Target Neighborhood Hits	540	Shared Neighborhood Hits	36
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MRCKB_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.030634 (rank : 99)
Query Neighborhood Hits	81	Target Neighborhood Hits	2180	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKG_MOUSE
θ value	1.06291 (rank : 52)	NC score	0.020118 (rank : 102)
Query Neighborhood Hits	81	Target Neighborhood Hits	1466	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PLEC1_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.049202 (rank : 91)
Query Neighborhood Hits	81	Target Neighborhood Hits	1326	Shared Neighborhood Hits	46
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

K2C5_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.054957 (rank : 69)
Query Neighborhood Hits	81	Target Neighborhood Hits	505	Shared Neighborhood Hits	34
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

SPTN5_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.036464 (rank : 94)
Query Neighborhood Hits	81	Target Neighborhood Hits	674	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

TITIN_HUMAN
θ value	1.81305 (rank : 56)	NC score	0.007527 (rank : 112)
Query Neighborhood Hits	81	Target Neighborhood Hits	2923	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TXD10_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.231673 (rank : 20)
Query Neighborhood Hits	81	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

IBP1_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.019690 (rank : 103)
Query Neighborhood Hits	81	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

TPR_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.054450 (rank : 70)
Query Neighborhood Hits	81	Target Neighborhood Hits	1921	Shared Neighborhood Hits	49
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

K2C1B_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.057274 (rank : 58)
Query Neighborhood Hits	81	Target Neighborhood Hits	542	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

K2C5_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.055946 (rank : 63)
Query Neighborhood Hits	81	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P13647, Q6PI71, Q6UBJ0, Q8TA91	Gene names	KRT5
Domain Architecture
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin).

A16L1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.028303 (rank : 100)
Query Neighborhood Hits	81	Target Neighborhood Hits	776	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

ARSG_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.014017 (rank : 109)
Query Neighborhood Hits	81	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

CMTA2_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.017624 (rank : 105)
Query Neighborhood Hits	81	Target Neighborhood Hits	216	Shared Neighborhood Hits	3
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CCD13_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.052448 (rank : 78)
Query Neighborhood Hits	81	Target Neighborhood Hits	721	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CNTN6_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.004908 (rank : 113)
Query Neighborhood Hits	81	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

ZN294_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.018158 (rank : 104)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

CI093_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.050853 (rank : 85)
Query Neighborhood Hits	81	Target Neighborhood Hits	1088	Shared Neighborhood Hits	45
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

MAS_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.007789 (rank : 111)
Query Neighborhood Hits	81	Target Neighborhood Hits	340	Shared Neighborhood Hits	3
SwissProt Accessions	P04201, Q6FG47	Gene names	MAS1, MAS
Domain Architecture
Description	MAS proto-oncogene.

PDCL3_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.014249 (rank : 108)
Query Neighborhood Hits	81	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

RABE2_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.058180 (rank : 56)
Query Neighborhood Hits	81	Target Neighborhood Hits	545	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RUFY1_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.036030 (rank : 95)
Query Neighborhood Hits	81	Target Neighborhood Hits	848	Shared Neighborhood Hits	36
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

THIOM_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.196024 (rank : 22)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.195438 (rank : 23)
Query Neighborhood Hits	81	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

ABCBB_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.003684 (rank : 115)
Query Neighborhood Hits	81	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).

DTNB_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.013138 (rank : 110)
Query Neighborhood Hits	81	Target Neighborhood Hits	263	Shared Neighborhood Hits	13
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

GOGA4_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.046978 (rank : 92)
Query Neighborhood Hits	81	Target Neighborhood Hits	1939	Shared Neighborhood Hits	48
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MAST1_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.003903 (rank : 114)
Query Neighborhood Hits	81	Target Neighborhood Hits	1146	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SPTB1_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.025521 (rank : 101)
Query Neighborhood Hits	81	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

TRPM7_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.016981 (rank : 107)
Query Neighborhood Hits	81	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM7_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.017149 (rank : 106)
Query Neighborhood Hits	81	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

CASQ1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.060889 (rank : 50)
Query Neighborhood Hits	81	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

CASQ1_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.055234 (rank : 67)
Query Neighborhood Hits	81	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	O09165	Gene names	Casq1
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform).

CASQ2_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.059272 (rank : 54)
Query Neighborhood Hits	81	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

CASQ2_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.052540 (rank : 77)
Query Neighborhood Hits	81	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	O09161, O88505	Gene names	Casq2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

CING_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.051578 (rank : 80)
Query Neighborhood Hits	81	Target Neighborhood Hits	1432	Shared Neighborhood Hits	46
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CP250_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.050146 (rank : 89)
Query Neighborhood Hits	81	Target Neighborhood Hits	1583	Shared Neighborhood Hits	46
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

EP15_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.064888 (rank : 46)
Query Neighborhood Hits	81	Target Neighborhood Hits	1021	Shared Neighborhood Hits	45
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GFAP_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.050351 (rank : 87)
Query Neighborhood Hits	81	Target Neighborhood Hits	725	Shared Neighborhood Hits	43
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

K22O_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.051776 (rank : 79)
Query Neighborhood Hits	81	Target Neighborhood Hits	485	Shared Neighborhood Hits	33
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

K2C1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.050325 (rank : 88)
Query Neighborhood Hits	81	Target Neighborhood Hits	624	Shared Neighborhood Hits	33
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

K2C3_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.050044 (rank : 90)
Query Neighborhood Hits	81	Target Neighborhood Hits	443	Shared Neighborhood Hits	33
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

K2C4_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.053008 (rank : 75)
Query Neighborhood Hits	81	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

K2C4_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.051323 (rank : 82)
Query Neighborhood Hits	81	Target Neighborhood Hits	521	Shared Neighborhood Hits	36
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

K2C6G_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.051148 (rank : 84)
Query Neighborhood Hits	81	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

K2C7_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.050581 (rank : 86)
Query Neighborhood Hits	81	Target Neighborhood Hits	369	Shared Neighborhood Hits	31
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

MACOI_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.062866 (rank : 47)
Query Neighborhood Hits	81	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.062593 (rank : 48)
Query Neighborhood Hits	81	Target Neighborhood Hits	620	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

MD1L1_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.053225 (rank : 74)
Query Neighborhood Hits	81	Target Neighborhood Hits	893	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

QSC6L_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.101648 (rank : 33)
Query Neighborhood Hits	81	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZRP7, Q5TB37, Q7Z7B6, Q86VV7, Q8N3G2	Gene names	QSCN6L1, QSOX2, SOXN
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase).

QSC6L_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.092215 (rank : 34)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q3TMX7, Q3TZA5, Q8C9I4, Q8K0M2	Gene names	Qscn6l1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1).

QSCN6_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.104830 (rank : 32)
Query Neighborhood Hits	81	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

QSCN6_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.113164 (rank : 30)
Query Neighborhood Hits	81	Target Neighborhood Hits	62	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

RABE1_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.053346 (rank : 73)
Query Neighborhood Hits	81	Target Neighborhood Hits	1104	Shared Neighborhood Hits	45
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.052555 (rank : 76)
Query Neighborhood Hits	81	Target Neighborhood Hits	1105	Shared Neighborhood Hits	45
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

THIO_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.121453 (rank : 27)
Query Neighborhood Hits	81	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

THIO_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.111588 (rank : 31)
Query Neighborhood Hits	81	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

TXD13_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.134563 (rank : 26)
Query Neighborhood Hits	81	Target Neighborhood Hits	106	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXD13_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.135121 (rank : 25)
Query Neighborhood Hits	81	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXND2_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.051473 (rank : 81)
Query Neighborhood Hits	81	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TXND6_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.068126 (rank : 40)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

TXND8_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.055723 (rank : 66)
Query Neighborhood Hits	81	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXND8_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.139446 (rank : 24)
Query Neighborhood Hits	81	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXNL2_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.117037 (rank : 29)
Query Neighborhood Hits	81	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXNL2_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.085012 (rank : 35)
Query Neighborhood Hits	81	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

Hits sorted by NC score

TXD11_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

TXD11_HUMAN
NC score	0.859562 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	81	Target Neighborhood Hits	402	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

PDIA3_MOUSE
NC score	0.421889 (rank : 3)	θ value	5.62301e-10 (rank : 3)
Query Neighborhood Hits	81	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA3_HUMAN
NC score	0.417199 (rank : 4)	θ value	3.64472e-09 (rank : 4)
Query Neighborhood Hits	81	Target Neighborhood Hits	57	Shared Neighborhood Hits	25
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

PDIA4_HUMAN
NC score	0.390190 (rank : 5)	θ value	6.87365e-08 (rank : 5)
Query Neighborhood Hits	81	Target Neighborhood Hits	60	Shared Neighborhood Hits	25
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA4_MOUSE
NC score	0.380424 (rank : 6)	θ value	1.29631e-06 (rank : 6)
Query Neighborhood Hits	81	Target Neighborhood Hits	57	Shared Neighborhood Hits	26
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA2_HUMAN
NC score	0.343667 (rank : 7)	θ value	0.00298849 (rank : 9)
Query Neighborhood Hits	81	Target Neighborhood Hits	49	Shared Neighborhood Hits	23
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA1_HUMAN
NC score	0.343049 (rank : 8)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	81	Target Neighborhood Hits	56	Shared Neighborhood Hits	26
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

PDIA1_MOUSE
NC score	0.339444 (rank : 9)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	81	Target Neighborhood Hits	50	Shared Neighborhood Hits	25
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA6_MOUSE
NC score	0.313619 (rank : 10)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	81	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

PDIA6_HUMAN
NC score	0.307022 (rank : 11)	θ value	0.0193708 (rank : 12)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

PDIA5_MOUSE
NC score	0.288263 (rank : 12)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	24
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXND4_HUMAN
NC score	0.283322 (rank : 13)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	81	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

TXND5_MOUSE
NC score	0.282748 (rank : 14)	θ value	0.0431538 (rank : 15)
Query Neighborhood Hits	81	Target Neighborhood Hits	52	Shared Neighborhood Hits	24
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND4_MOUSE
NC score	0.278872 (rank : 15)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	81	Target Neighborhood Hits	44	Shared Neighborhood Hits	24
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA5_HUMAN
NC score	0.278449 (rank : 16)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	81	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXND5_HUMAN
NC score	0.272934 (rank : 17)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	81	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

TXND1_HUMAN
NC score	0.244529 (rank : 18)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	81	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3N1, Q8N487, Q8NBN5, Q9Y4T6	Gene names	TXNDC1, TMX, TXNDC
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor (Transmembrane Trx- related protein) (Thioredoxin-related transmembrane protein).

TXD10_MOUSE
NC score	0.243612 (rank : 19)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	81	Target Neighborhood Hits	48	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BXZ1, Q3US84, Q6PGA1, Q6ZPH5, Q8BZB8	Gene names	Txndc10, Kiaa1830
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10).

TXD10_HUMAN
NC score	0.231673 (rank : 20)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	81	Target Neighborhood Hits	47	Shared Neighborhood Hits	24
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

TXND1_MOUSE
NC score	0.223433 (rank : 21)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VBT0, Q3UCI8, Q9CSD5	Gene names	Txndc1, Txndc
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor.

THIOM_HUMAN
NC score	0.196024 (rank : 22)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	25
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
NC score	0.195438 (rank : 23)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	81	Target Neighborhood Hits	45	Shared Neighborhood Hits	25
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

TXND8_MOUSE
NC score	0.139446 (rank : 24)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	81	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXD13_MOUSE
NC score	0.135121 (rank : 25)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	81	Target Neighborhood Hits	61	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXD13_HUMAN
NC score	0.134563 (rank : 26)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	81	Target Neighborhood Hits	106	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

THIO_HUMAN
NC score	0.121453 (rank : 27)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	81	Target Neighborhood Hits	43	Shared Neighborhood Hits	23
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

TXND3_HUMAN
NC score	0.118916 (rank : 28)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	81	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

TXNL2_HUMAN
NC score	0.117037 (rank : 29)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	81	Target Neighborhood Hits	59	Shared Neighborhood Hits	25
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

QSCN6_MOUSE
NC score	0.113164 (rank : 30)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	81	Target Neighborhood Hits	62	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

THIO_MOUSE
NC score	0.111588 (rank : 31)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	81	Target Neighborhood Hits	39	Shared Neighborhood Hits	22
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

QSCN6_HUMAN
NC score	0.104830 (rank : 32)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	81	Target Neighborhood Hits	98	Shared Neighborhood Hits	21
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

QSC6L_HUMAN
NC score	0.101648 (rank : 33)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	81	Target Neighborhood Hits	35	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZRP7, Q5TB37, Q7Z7B6, Q86VV7, Q8N3G2	Gene names	QSCN6L1, QSOX2, SOXN
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase).

QSC6L_MOUSE
NC score	0.092215 (rank : 34)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	81	Target Neighborhood Hits	36	Shared Neighborhood Hits	17
SwissProt Accessions	Q3TMX7, Q3TZA5, Q8C9I4, Q8K0M2	Gene names	Qscn6l1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1).

TXNL2_MOUSE
NC score	0.085012 (rank : 35)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	81	Target Neighborhood Hits	54	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

ADIP_MOUSE
NC score	0.084845 (rank : 36)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	81	Target Neighborhood Hits	415	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

TXND3_MOUSE
NC score	0.084248 (rank : 37)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	81	Target Neighborhood Hits	51	Shared Neighborhood Hits	13
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

ADIP_HUMAN
NC score	0.082243 (rank : 38)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	81	Target Neighborhood Hits	470	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

CASP_MOUSE
NC score	0.068142 (rank : 39)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	81	Target Neighborhood Hits	1152	Shared Neighborhood Hits	42
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

TXND6_HUMAN
NC score	0.068126 (rank : 40)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	81	Target Neighborhood Hits	46	Shared Neighborhood Hits	16
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

CUTL1_MOUSE
NC score	0.067423 (rank : 41)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	81	Target Neighborhood Hits	1620	Shared Neighborhood Hits	41
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

LZTS1_MOUSE
NC score	0.066666 (rank : 42)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	81	Target Neighborhood Hits	540	Shared Neighborhood Hits	36
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

CASP_HUMAN
NC score	0.066610 (rank : 43)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	81	Target Neighborhood Hits	1131	Shared Neighborhood Hits	41
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CP135_MOUSE
NC score	0.066228 (rank : 44)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	81	Target Neighborhood Hits	1278	Shared Neighborhood Hits	46
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CUTL1_HUMAN
NC score	0.065202 (rank : 45)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	81	Target Neighborhood Hits	1574	Shared Neighborhood Hits	41
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

EP15_HUMAN
NC score	0.064888 (rank : 46)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	81	Target Neighborhood Hits	1021	Shared Neighborhood Hits	45
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MACOI_HUMAN
NC score	0.062866 (rank : 47)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	81	Target Neighborhood Hits	650	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

MACOI_MOUSE
NC score	0.062593 (rank : 48)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	81	Target Neighborhood Hits	620	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TQE6	Gene names	Tmem57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57) (Brain-specific adaptor protein C61).

FYCO1_HUMAN
NC score	0.061030 (rank : 49)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	81	Target Neighborhood Hits	1149	Shared Neighborhood Hits	45
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

CASQ1_HUMAN
NC score	0.060889 (rank : 50)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	81	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

FYCO1_MOUSE
NC score	0.060875 (rank : 51)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	81	Target Neighborhood Hits	1059	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

TRAIP_MOUSE
NC score	0.060633 (rank : 52)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	81	Target Neighborhood Hits	745	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VIG6, O08854, Q922M8, Q9CPP4	Gene names	Traip, Trip
Domain Architecture
Description	TRAF-interacting protein.

MYOC_HUMAN
NC score	0.059960 (rank : 53)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	81	Target Neighborhood Hits	489	Shared Neighborhood Hits	25
SwissProt Accessions	Q99972, O00620, Q7Z6Q9	Gene names	MYOC, GLC1A, TIGR
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

CASQ2_HUMAN
NC score	0.059272 (rank : 54)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	81	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

RABE2_MOUSE
NC score	0.058745 (rank : 55)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	81	Target Neighborhood Hits	598	Shared Neighborhood Hits	34
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RABE2_HUMAN
NC score	0.058180 (rank : 56)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	81	Target Neighborhood Hits	545	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

K2C1B_MOUSE
NC score	0.057516 (rank : 57)	θ value	0.47712 (rank : 28)
Query Neighborhood Hits	81	Target Neighborhood Hits	503	Shared Neighborhood Hits	30
SwissProt Accessions	Q6IFZ6	Gene names	Krt1b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b (Type II keratin Kb39) (Embryonic type II keratin-1).

K2C1B_HUMAN
NC score	0.057274 (rank : 58)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	81	Target Neighborhood Hits	542	Shared Neighborhood Hits	37
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

K2C6E_HUMAN
NC score	0.056768 (rank : 59)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	81	Target Neighborhood Hits	516	Shared Neighborhood Hits	35
SwissProt Accessions	P48668, Q7RTN9	Gene names	KRT6E
Domain Architecture
Description	Keratin, type II cytoskeletal 6E (Cytokeratin-6E) (CK 6E) (K6e keratin) (Keratin K6h).

K2C6B_HUMAN
NC score	0.056552 (rank : 60)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	81	Target Neighborhood Hits	526	Shared Neighborhood Hits	35
SwissProt Accessions	P04259, P48669	Gene names	KRT6B, K6B
Domain Architecture
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin).

CING_HUMAN
NC score	0.056454 (rank : 61)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	81	Target Neighborhood Hits	1275	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CP135_HUMAN
NC score	0.056403 (rank : 62)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	81	Target Neighborhood Hits	1290	Shared Neighborhood Hits	43
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

K2C5_HUMAN
NC score	0.055946 (rank : 63)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	81	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P13647, Q6PI71, Q6UBJ0, Q8TA91	Gene names	KRT5
Domain Architecture
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin).

K2C6C_HUMAN
NC score	0.055907 (rank : 64)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	81	Target Neighborhood Hits	503	Shared Neighborhood Hits	36
SwissProt Accessions	P48666	Gene names	KRT6C
Domain Architecture
Description	Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin).

K2C6A_HUMAN
NC score	0.055797 (rank : 65)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	81	Target Neighborhood Hits	505	Shared Neighborhood Hits	36
SwissProt Accessions	P02538, Q6NT67, Q96CL4	Gene names	KRT6A, K6A
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin).

TXND8_HUMAN
NC score	0.055723 (rank : 66)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	81	Target Neighborhood Hits	27	Shared Neighborhood Hits	16
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

CASQ1_MOUSE
NC score	0.055234 (rank : 67)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	81	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	O09165	Gene names	Casq1
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform).

K2C6B_MOUSE
NC score	0.055035 (rank : 68)	θ value	0.47712 (rank : 29)
Query Neighborhood Hits	81	Target Neighborhood Hits	506	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z331	Gene names	Krt6b, K6-beta, Krt2-6b
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin) (Keratin-6 beta) (mK6-beta).

K2C5_MOUSE
NC score	0.054957 (rank : 69)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	81	Target Neighborhood Hits	505	Shared Neighborhood Hits	34
SwissProt Accessions	Q922U2, Q920F2	Gene names	Krt5, Krt2-5
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5).

TPR_HUMAN
NC score	0.054450 (rank : 70)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	81	Target Neighborhood Hits	1921	Shared Neighborhood Hits	49
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

EP15R_MOUSE
NC score	0.054415 (rank : 71)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	81	Target Neighborhood Hits	1135	Shared Neighborhood Hits	44
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

K2C6A_MOUSE
NC score	0.053783 (rank : 72)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	81	Target Neighborhood Hits	481	Shared Neighborhood Hits	33
SwissProt Accessions	P50446, Q9Z332	Gene names	Krt6a, Ker2, Krt2-6, Krt2-6a, Krt6
Domain Architecture
Description	Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin) (Keratin-6 alpha) (mK6-alpha).

RABE1_HUMAN
NC score	0.053346 (rank : 73)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	81	Target Neighborhood Hits	1104	Shared Neighborhood Hits	45
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

MD1L1_HUMAN
NC score	0.053225 (rank : 74)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	81	Target Neighborhood Hits	893	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

K2C4_HUMAN
NC score	0.053008 (rank : 75)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	81	Target Neighborhood Hits	471	Shared Neighborhood Hits	31
SwissProt Accessions	P19013, Q6GTR8, Q96LA7, Q9BTL1	Gene names	KRT4, CYK4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4).

RABE1_MOUSE
NC score	0.052555 (rank : 76)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	81	Target Neighborhood Hits	1105	Shared Neighborhood Hits	45
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

CASQ2_MOUSE
NC score	0.052540 (rank : 77)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	81	Target Neighborhood Hits	34	Shared Neighborhood Hits	8
SwissProt Accessions	O09161, O88505	Gene names	Casq2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

CCD13_HUMAN
NC score	0.052448 (rank : 78)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	81	Target Neighborhood Hits	721	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

K22O_HUMAN
NC score	0.051776 (rank : 79)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	81	Target Neighborhood Hits	485	Shared Neighborhood Hits	33
SwissProt Accessions	Q01546, Q7Z795	Gene names	KRT76, KRT2B, KRT2P
Domain Architecture
Description	Keratin, type II cytoskeletal 2 oral (Cytokeratin-2P) (K2P) (CK 2P) (Keratin 76).

CING_MOUSE
NC score	0.051578 (rank : 80)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	81	Target Neighborhood Hits	1432	Shared Neighborhood Hits	46
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

TXND2_MOUSE
NC score	0.051473 (rank : 81)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	81	Target Neighborhood Hits	828	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

K2C4_MOUSE
NC score	0.051323 (rank : 82)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	81	Target Neighborhood Hits	521	Shared Neighborhood Hits	36
SwissProt Accessions	P07744, Q6P3F5	Gene names	Krt4, Krt2-4
Domain Architecture
Description	Keratin, type II cytoskeletal 4 (Cytokeratin-4) (CK-4) (Keratin-4) (K4) (Cytoskeletal 57 kDa keratin).

CCD41_MOUSE
NC score	0.051311 (rank : 83)	θ value	0.365318 (rank : 26)
Query Neighborhood Hits	81	Target Neighborhood Hits	1399	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

K2C6G_MOUSE
NC score	0.051148 (rank : 84)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	81	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R0H5, Q7TPF3, Q9D0X6	Gene names	Krt6g, K6irs1, Krt2-6g
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 6G (Cytokeratin-6G) (CK 6G) (K6g keratin) (Keratin-K6irs) (mK6irs1/Krt2-6g).

CI093_HUMAN
NC score	0.050853 (rank : 85)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	81	Target Neighborhood Hits	1088	Shared Neighborhood Hits	45
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

K2C7_HUMAN
NC score	0.050581 (rank : 86)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	81	Target Neighborhood Hits	369	Shared Neighborhood Hits	31
SwissProt Accessions	P08729, Q92676, Q9BUD8, Q9Y3R7	Gene names	KRT7, SCL
Domain Architecture
Description	Keratin, type II cytoskeletal 7 (Cytokeratin-7) (CK-7) (Keratin-7) (K7) (Sarcolectin).

GFAP_MOUSE
NC score	0.050351 (rank : 87)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	81	Target Neighborhood Hits	725	Shared Neighborhood Hits	43
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

K2C1_HUMAN
NC score	0.050325 (rank : 88)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	81	Target Neighborhood Hits	624	Shared Neighborhood Hits	33
SwissProt Accessions	P04264, Q14720, Q6GSJ0, Q9H298	Gene names	KRT1, KRTA
Domain Architecture
Description	Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein).

CP250_MOUSE
NC score	0.050146 (rank : 89)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	81	Target Neighborhood Hits	1583	Shared Neighborhood Hits	46
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

K2C3_HUMAN
NC score	0.050044 (rank : 90)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	81	Target Neighborhood Hits	443	Shared Neighborhood Hits	33
SwissProt Accessions	P12035, Q701L8	Gene names	KRT3
Domain Architecture
Description	Keratin, type II cytoskeletal 3 (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (65 kDa cytokeratin).

PLEC1_HUMAN
NC score	0.049202 (rank : 91)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	81	Target Neighborhood Hits	1326	Shared Neighborhood Hits	46
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

GOGA4_MOUSE
NC score	0.046978 (rank : 92)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	81	Target Neighborhood Hits	1939	Shared Neighborhood Hits	48
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

KI21A_HUMAN
NC score	0.044045 (rank : 93)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	81	Target Neighborhood Hits	1543	Shared Neighborhood Hits	43
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

SPTN5_HUMAN
NC score	0.036464 (rank : 94)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	81	Target Neighborhood Hits	674	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NRC6	Gene names	SPTBN5, SPTBN4
Domain Architecture
Description	Spectrin beta chain, brain 4 (Spectrin, non-erythroid beta chain 4) (Beta-V spectrin) (BSPECV).

RUFY1_HUMAN
NC score	0.036030 (rank : 95)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	81	Target Neighborhood Hits	848	Shared Neighborhood Hits	36
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

KI21A_MOUSE
NC score	0.035873 (rank : 96)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	81	Target Neighborhood Hits	1317	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

A16L1_HUMAN
NC score	0.035102 (rank : 97)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	81	Target Neighborhood Hits	664	Shared Neighborhood Hits	24
SwissProt Accessions	Q676U5, Q6IPN1, Q6UXW4, Q6ZVZ5, Q8NCY2, Q96JV5, Q9H619	Gene names	ATG16L1, APG16L
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

MRCKB_HUMAN
NC score	0.032839 (rank : 98)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	81	Target Neighborhood Hits	2239	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_MOUSE
NC score	0.030634 (rank : 99)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	81	Target Neighborhood Hits	2180	Shared Neighborhood Hits	48
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

A16L1_MOUSE
NC score	0.028303 (rank : 100)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	81	Target Neighborhood Hits	776	Shared Neighborhood Hits	26
SwissProt Accessions	Q8C0J2, Q6KAT7, Q80U97, Q80U98, Q80U99, Q80Y53, Q9DB63	Gene names	Atg16l1, Apg16l
Domain Architecture	No domain graphic available
Description	Autophagy-related protein 16-1 (APG16-like 1).

SPTB1_MOUSE
NC score	0.025521 (rank : 101)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	81	Target Neighborhood Hits	543	Shared Neighborhood Hits	28
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

MRCKG_MOUSE
NC score	0.020118 (rank : 102)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	81	Target Neighborhood Hits	1466	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

IBP1_MOUSE
NC score	0.019690 (rank : 103)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	81	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

ZN294_MOUSE
NC score	0.018158 (rank : 104)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	81	Target Neighborhood Hits	81	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A009, Q6PIW6, Q8BZ44	Gene names	Znf294, Kiaa0714, zfp294
Domain Architecture	No domain graphic available
Description	Zinc finger protein 294 (Zfp-294).

CMTA2_MOUSE
NC score	0.017624 (rank : 105)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	81	Target Neighborhood Hits	216	Shared Neighborhood Hits	3
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPM7_MOUSE
NC score	0.017149 (rank : 106)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	81	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
NC score	0.016981 (rank : 107)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	81	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

PDCL3_MOUSE
NC score	0.014249 (rank : 108)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	81	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BVF2, Q3TH06, Q99JX2, Q9D0W3	Gene names	Pdcl3, Viaf1
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 3 (Viral IAP-associated factor 1) (VIAF-1).

ARSG_HUMAN
NC score	0.014017 (rank : 109)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	81	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EG1, Q6UXF2, Q9Y2K4	Gene names	ARSG, KIAA1001
Domain Architecture	No domain graphic available
Description	Arylsulfatase G precursor (EC 3.1.6.-) (ASG).

DTNB_MOUSE
NC score	0.013138 (rank : 110)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	81	Target Neighborhood Hits	263	Shared Neighborhood Hits	13
SwissProt Accessions	O70585, O70563, Q9CTZ1	Gene names	Dtnb
Domain Architecture
Description	Dystrobrevin beta (Beta-dystrobrevin) (DTN-B) (MDTN-B).

MAS_HUMAN
NC score	0.007789 (rank : 111)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	81	Target Neighborhood Hits	340	Shared Neighborhood Hits	3
SwissProt Accessions	P04201, Q6FG47	Gene names	MAS1, MAS
Domain Architecture
Description	MAS proto-oncogene.

TITIN_HUMAN
NC score	0.007527 (rank : 112)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	81	Target Neighborhood Hits	2923	Shared Neighborhood Hits	27
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CNTN6_MOUSE
NC score	0.004908 (rank : 113)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	81	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

MAST1_HUMAN
NC score	0.003903 (rank : 114)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	81	Target Neighborhood Hits	1146	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

ABCBB_HUMAN
NC score	0.003684 (rank : 115)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	81	Target Neighborhood Hits	103	Shared Neighborhood Hits	3
SwissProt Accessions	O95342, Q9UNB2	Gene names	ABCB11, BSEP
Domain Architecture
Description	Bile salt export pump (ATP-binding cassette sub-family B member 11).