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Network neighborhood for query Sequence : TRPM7_HUMAN

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TRPM7_HUMAN
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPM3_HUMAN
θ value	0 (rank : 1)	NC score	0.961433 (rank : 5)
Query Neighborhood Hits	104	Target Neighborhood Hits	121	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM6_HUMAN
θ value	0 (rank : 2)	NC score	0.975906 (rank : 4)
Query Neighborhood Hits	104	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_MOUSE
θ value	0 (rank : 3)	NC score	0.977476 (rank : 3)
Query Neighborhood Hits	104	Target Neighborhood Hits	78	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM7_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	104	Target Neighborhood Hits	104	Shared Neighborhood Hits	104
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM7_MOUSE
θ value	0 (rank : 5)	NC score	0.995423 (rank : 2)
Query Neighborhood Hits	104	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM2_HUMAN
θ value	3.27947e-143 (rank : 6)	NC score	0.858745 (rank : 7)
Query Neighborhood Hits	104	Target Neighborhood Hits	64	Shared Neighborhood Hits	33
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
θ value	1.52337e-140 (rank : 7)	NC score	0.861586 (rank : 6)
Query Neighborhood Hits	104	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM8_HUMAN
θ value	3.35642e-63 (rank : 8)	NC score	0.845135 (rank : 8)
Query Neighborhood Hits	104	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
θ value	5.0155e-59 (rank : 9)	NC score	0.841301 (rank : 9)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPC4_HUMAN
θ value	4.02038e-16 (rank : 10)	NC score	0.494015 (rank : 10)
Query Neighborhood Hits	104	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	5.25075e-16 (rank : 11)	NC score	0.492805 (rank : 11)
Query Neighborhood Hits	104	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	1.86753e-13 (rank : 12)	NC score	0.475208 (rank : 13)
Query Neighborhood Hits	104	Target Neighborhood Hits	122	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	1.86753e-13 (rank : 13)	NC score	0.475440 (rank : 12)
Query Neighborhood Hits	104	Target Neighborhood Hits	124	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC2_MOUSE
θ value	6.64225e-11 (rank : 14)	NC score	0.441360 (rank : 14)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

EF2K_MOUSE
θ value	1.47974e-10 (rank : 15)	NC score	0.326661 (rank : 23)
Query Neighborhood Hits	104	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

TRPC3_MOUSE
θ value	2.52405e-10 (rank : 16)	NC score	0.421239 (rank : 15)
Query Neighborhood Hits	104	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

EF2K_HUMAN
θ value	9.59137e-10 (rank : 17)	NC score	0.318571 (rank : 24)
Query Neighborhood Hits	104	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

TRPC6_HUMAN
θ value	1.63604e-09 (rank : 18)	NC score	0.388170 (rank : 18)
Query Neighborhood Hits	104	Target Neighborhood Hits	171	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	2.79066e-09 (rank : 19)	NC score	0.388692 (rank : 17)
Query Neighborhood Hits	104	Target Neighborhood Hits	171	Shared Neighborhood Hits	39
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	3.64472e-09 (rank : 20)	NC score	0.378681 (rank : 20)
Query Neighborhood Hits	104	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	3.64472e-09 (rank : 21)	NC score	0.379377 (rank : 19)
Query Neighborhood Hits	104	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC3_HUMAN
θ value	6.21693e-09 (rank : 22)	NC score	0.411242 (rank : 16)
Query Neighborhood Hits	104	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

PK2L1_HUMAN
θ value	0.000786445 (rank : 23)	NC score	0.138072 (rank : 31)
Query Neighborhood Hits	104	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPC1_HUMAN
θ value	0.00134147 (rank : 24)	NC score	0.353861 (rank : 22)
Query Neighborhood Hits	104	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	0.00134147 (rank : 25)	NC score	0.354114 (rank : 21)
Query Neighborhood Hits	104	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

PK2L2_MOUSE
θ value	0.00228821 (rank : 26)	NC score	0.116111 (rank : 39)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PCNT_MOUSE
θ value	0.00869519 (rank : 27)	NC score	0.043550 (rank : 46)
Query Neighborhood Hits	104	Target Neighborhood Hits	1207	Shared Neighborhood Hits	34
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

LUZP1_MOUSE
θ value	0.0193708 (rank : 28)	NC score	0.036778 (rank : 48)
Query Neighborhood Hits	104	Target Neighborhood Hits	940	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

TRPV3_MOUSE
θ value	0.0193708 (rank : 29)	NC score	0.212980 (rank : 25)
Query Neighborhood Hits	104	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

ACINU_HUMAN
θ value	0.0252991 (rank : 30)	NC score	0.044629 (rank : 45)
Query Neighborhood Hits	104	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PK2L2_HUMAN
θ value	0.0431538 (rank : 31)	NC score	0.099600 (rank : 40)
Query Neighborhood Hits	104	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV3_HUMAN
θ value	0.0431538 (rank : 32)	NC score	0.212401 (rank : 26)
Query Neighborhood Hits	104	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV6_HUMAN
θ value	0.0736092 (rank : 33)	NC score	0.147908 (rank : 29)
Query Neighborhood Hits	104	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

RGS1_MOUSE
θ value	0.125558 (rank : 34)	NC score	0.028088 (rank : 52)
Query Neighborhood Hits	104	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

AKAP9_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.036876 (rank : 47)
Query Neighborhood Hits	104	Target Neighborhood Hits	1710	Shared Neighborhood Hits	44
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CNGA1_HUMAN
θ value	0.163984 (rank : 36)	NC score	0.019098 (rank : 67)
Query Neighborhood Hits	104	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

STAT1_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.014686 (rank : 80)
Query Neighborhood Hits	104	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

TRPV6_MOUSE
θ value	0.47712 (rank : 38)	NC score	0.132679 (rank : 33)
Query Neighborhood Hits	104	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

LAMA2_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.009671 (rank : 95)
Query Neighborhood Hits	104	Target Neighborhood Hits	1198	Shared Neighborhood Hits	25
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

SM1L2_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.019433 (rank : 65)
Query Neighborhood Hits	104	Target Neighborhood Hits	1019	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

TRPV5_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.129181 (rank : 35)
Query Neighborhood Hits	104	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV1_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.142636 (rank : 30)
Query Neighborhood Hits	104	Target Neighborhood Hits	184	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

CING_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.018458 (rank : 69)
Query Neighborhood Hits	104	Target Neighborhood Hits	1275	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

LMNA_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.025491 (rank : 58)
Query Neighborhood Hits	104	Target Neighborhood Hits	653	Shared Neighborhood Hits	27
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

LMNA_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.025629 (rank : 56)
Query Neighborhood Hits	104	Target Neighborhood Hits	661	Shared Neighborhood Hits	27
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

MYH7_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.012118 (rank : 88)
Query Neighborhood Hits	104	Target Neighborhood Hits	1559	Shared Neighborhood Hits	36
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RBM25_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.020222 (rank : 64)
Query Neighborhood Hits	104	Target Neighborhood Hits	682	Shared Neighborhood Hits	20
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TRPV2_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.097371 (rank : 41)
Query Neighborhood Hits	104	Target Neighborhood Hits	111	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

UBXD2_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.025577 (rank : 57)
Query Neighborhood Hits	104	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

KIF3B_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.014283 (rank : 81)
Query Neighborhood Hits	104	Target Neighborhood Hits	540	Shared Neighborhood Hits	23
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

KIF3B_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.013096 (rank : 83)
Query Neighborhood Hits	104	Target Neighborhood Hits	533	Shared Neighborhood Hits	22
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

LUZP1_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.028145 (rank : 51)
Query Neighborhood Hits	104	Target Neighborhood Hits	739	Shared Neighborhood Hits	26
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

SYNE1_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.021867 (rank : 61)
Query Neighborhood Hits	104	Target Neighborhood Hits	1484	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TRAK2_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.027667 (rank : 53)
Query Neighborhood Hits	104	Target Neighborhood Hits	476	Shared Neighborhood Hits	22
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

TRPV1_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.136525 (rank : 32)
Query Neighborhood Hits	104	Target Neighborhood Hits	189	Shared Neighborhood Hits	34
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ACINU_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.026828 (rank : 54)
Query Neighborhood Hits	104	Target Neighborhood Hits	712	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LMAN1_MOUSE
θ value	1.81305 (rank : 57)	NC score	0.026817 (rank : 55)
Query Neighborhood Hits	104	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D0F3	Gene names	Lman1, Ergic53
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (p58).

PHF12_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.012915 (rank : 84)
Query Neighborhood Hits	104	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BPAEA_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.016304 (rank : 76)
Query Neighborhood Hits	104	Target Neighborhood Hits	1369	Shared Neighborhood Hits	39
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

EEA1_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.018289 (rank : 70)
Query Neighborhood Hits	104	Target Neighborhood Hits	1796	Shared Neighborhood Hits	45
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

TRPV5_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.124194 (rank : 36)
Query Neighborhood Hits	104	Target Neighborhood Hits	278	Shared Neighborhood Hits	38
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

DEMA_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.010956 (rank : 90)
Query Neighborhood Hits	104	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

PROM1_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.020697 (rank : 62)
Query Neighborhood Hits	104	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

SENP1_MOUSE
θ value	3.0926 (rank : 64)	NC score	0.010822 (rank : 91)
Query Neighborhood Hits	104	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

SH3G1_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.007916 (rank : 102)
Query Neighborhood Hits	104	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

TXD11_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.022219 (rank : 60)
Query Neighborhood Hits	104	Target Neighborhood Hits	402	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

AT1B1_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.009160 (rank : 97)
Query Neighborhood Hits	104	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P05026, Q5TGZ3	Gene names	ATP1B1, ATP1B
Domain Architecture
Description	Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium- dependent ATPase beta-1 subunit).

BRD8_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.023460 (rank : 59)
Query Neighborhood Hits	104	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CC47_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.029192 (rank : 50)
Query Neighborhood Hits	104	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CCD47_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.032749 (rank : 49)
Query Neighborhood Hits	104	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

GCC2_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.012868 (rank : 85)
Query Neighborhood Hits	104	Target Neighborhood Hits	1619	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

HOOK1_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.012234 (rank : 87)
Query Neighborhood Hits	104	Target Neighborhood Hits	942	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MYST4_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.009879 (rank : 94)
Query Neighborhood Hits	104	Target Neighborhood Hits	416	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RCOR2_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.010116 (rank : 93)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

TPR_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.014763 (rank : 78)
Query Neighborhood Hits	104	Target Neighborhood Hits	1921	Shared Neighborhood Hits	42
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

DIAP2_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.008408 (rank : 101)
Query Neighborhood Hits	104	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

P73_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.008586 (rank : 100)
Query Neighborhood Hits	104	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

RAI14_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.019084 (rank : 68)
Query Neighborhood Hits	104	Target Neighborhood Hits	1367	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

TRPV4_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.132186 (rank : 34)
Query Neighborhood Hits	104	Target Neighborhood Hits	150	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

UBXD2_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.020330 (rank : 63)
Query Neighborhood Hits	104	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

3BP1_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.003908 (rank : 107)
Query Neighborhood Hits	104	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

CL011_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.010354 (rank : 92)
Query Neighborhood Hits	104	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8QZV7, Q99JT8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C12orf11 homolog.

CP7B1_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.006899 (rank : 105)
Query Neighborhood Hits	104	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q60991	Gene names	Cyp7b1
Domain Architecture
Description	Cytochrome P450 7B1 (EC 1.14.13.100) (25-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (HCT-1).

DIAP3_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.011665 (rank : 89)
Query Neighborhood Hits	104	Target Neighborhood Hits	209	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

GOGA4_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.012823 (rank : 86)
Query Neighborhood Hits	104	Target Neighborhood Hits	1939	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LIPS_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.009212 (rank : 96)
Query Neighborhood Hits	104	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

LMAN1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.019395 (rank : 66)
Query Neighborhood Hits	104	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	P49257, Q12895, Q8N5I7, Q9UQG1, Q9UQG2, Q9UQG3, Q9UQG4, Q9UQG5, Q9UQG6, Q9UQG7, Q9UQG8, Q9UQG9, Q9UQH0, Q9UQH1, Q9UQH2	Gene names	LMAN1, ERGIC53, F5F8D
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (Gp58) (Intracellular mannose- specific lectin MR60).

NOVA2_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.007160 (rank : 104)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

OR2H1_HUMAN
θ value	6.88961 (rank : 89)	NC score	-0.003080 (rank : 108)
Query Neighborhood Hits	104	Target Neighborhood Hits	755	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZK4, O43629, O43661, O43662, Q9GZK9	Gene names	OR2H1, OR2H6, OR2H8
Domain Architecture
Description	Olfactory receptor 2H1 (Hs6M1-16) (Olfactory receptor 6-2) (OR6-2) (OLFR42A-9004.14/9026.2).

RCOR2_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.008748 (rank : 99)
Query Neighborhood Hits	104	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

SH3G1_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.006309 (rank : 106)
Query Neighborhood Hits	104	Target Neighborhood Hits	291	Shared Neighborhood Hits	7
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

TRPV4_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.117652 (rank : 38)
Query Neighborhood Hits	104	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

BRD8_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.017844 (rank : 72)
Query Neighborhood Hits	104	Target Neighborhood Hits	422	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CCDC6_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.014693 (rank : 79)
Query Neighborhood Hits	104	Target Neighborhood Hits	723	Shared Neighborhood Hits	29
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CENPF_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.014790 (rank : 77)
Query Neighborhood Hits	104	Target Neighborhood Hits	1932	Shared Neighborhood Hits	42
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CKAP4_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.016312 (rank : 74)
Query Neighborhood Hits	104	Target Neighborhood Hits	592	Shared Neighborhood Hits	25
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

EEA1_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.013222 (rank : 82)
Query Neighborhood Hits	104	Target Neighborhood Hits	1637	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GOGB1_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.018090 (rank : 71)
Query Neighborhood Hits	104	Target Neighborhood Hits	2297	Shared Neighborhood Hits	44
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MCLN2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.016310 (rank : 75)
Query Neighborhood Hits	104	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

S4A11_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.007717 (rank : 103)
Query Neighborhood Hits	104	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBS3, Q9BXF4, Q9NTW9	Gene names	SLC4A11, BTR1
Domain Architecture
Description	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Solute carrier family 4 member 11).

TRPV2_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.076152 (rank : 42)
Query Neighborhood Hits	104	Target Neighborhood Hits	130	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TXD11_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.016981 (rank : 73)
Query Neighborhood Hits	104	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

UBP8_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.009159 (rank : 98)
Query Neighborhood Hits	104	Target Neighborhood Hits	751	Shared Neighborhood Hits	26
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

ZN548_HUMAN
θ value	8.99809 (rank : 104)	NC score	-0.003664 (rank : 109)
Query Neighborhood Hits	104	Target Neighborhood Hits	739	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEK5, Q96M05	Gene names	ZNF548
Domain Architecture	No domain graphic available
Description	Zinc finger protein 548.

NUD9P_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.117929 (rank : 37)
Query Neighborhood Hits	104	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

NUDT9_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.154602 (rank : 28)
Query Neighborhood Hits	104	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.155964 (rank : 27)
Query Neighborhood Hits	104	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

PKD2_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.073989 (rank : 43)
Query Neighborhood Hits	104	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.068312 (rank : 44)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

Hits sorted by NC score

TRPM7_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	104	Target Neighborhood Hits	104	Shared Neighborhood Hits	104
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM7_MOUSE
NC score	0.995423 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	104	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM6_MOUSE
NC score	0.977476 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	104	Target Neighborhood Hits	78	Shared Neighborhood Hits	35
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_HUMAN
NC score	0.975906 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	104	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM3_HUMAN
NC score	0.961433 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	104	Target Neighborhood Hits	121	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM2_MOUSE
NC score	0.861586 (rank : 6)	θ value	1.52337e-140 (rank : 7)
Query Neighborhood Hits	104	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM2_HUMAN
NC score	0.858745 (rank : 7)	θ value	3.27947e-143 (rank : 6)
Query Neighborhood Hits	104	Target Neighborhood Hits	64	Shared Neighborhood Hits	33
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM8_HUMAN
NC score	0.845135 (rank : 8)	θ value	3.35642e-63 (rank : 8)
Query Neighborhood Hits	104	Target Neighborhood Hits	65	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
NC score	0.841301 (rank : 9)	θ value	5.0155e-59 (rank : 9)
Query Neighborhood Hits	104	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPC4_HUMAN
NC score	0.494015 (rank : 10)	θ value	4.02038e-16 (rank : 10)
Query Neighborhood Hits	104	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.492805 (rank : 11)	θ value	5.25075e-16 (rank : 11)
Query Neighborhood Hits	104	Target Neighborhood Hits	141	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.475440 (rank : 12)	θ value	1.86753e-13 (rank : 13)
Query Neighborhood Hits	104	Target Neighborhood Hits	124	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.475208 (rank : 13)	θ value	1.86753e-13 (rank : 12)
Query Neighborhood Hits	104	Target Neighborhood Hits	122	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC2_MOUSE
NC score	0.441360 (rank : 14)	θ value	6.64225e-11 (rank : 14)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_MOUSE
NC score	0.421239 (rank : 15)	θ value	2.52405e-10 (rank : 16)
Query Neighborhood Hits	104	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC3_HUMAN
NC score	0.411242 (rank : 16)	θ value	6.21693e-09 (rank : 22)
Query Neighborhood Hits	104	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.388692 (rank : 17)	θ value	2.79066e-09 (rank : 19)
Query Neighborhood Hits	104	Target Neighborhood Hits	171	Shared Neighborhood Hits	39
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC6_HUMAN
NC score	0.388170 (rank : 18)	θ value	1.63604e-09 (rank : 18)
Query Neighborhood Hits	104	Target Neighborhood Hits	171	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_MOUSE
NC score	0.379377 (rank : 19)	θ value	3.64472e-09 (rank : 21)
Query Neighborhood Hits	104	Target Neighborhood Hits	114	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.378681 (rank : 20)	θ value	3.64472e-09 (rank : 20)
Query Neighborhood Hits	104	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC1_MOUSE
NC score	0.354114 (rank : 21)	θ value	0.00134147 (rank : 25)
Query Neighborhood Hits	104	Target Neighborhood Hits	87	Shared Neighborhood Hits	34
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.353861 (rank : 22)	θ value	0.00134147 (rank : 24)
Query Neighborhood Hits	104	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

EF2K_MOUSE
NC score	0.326661 (rank : 23)	θ value	1.47974e-10 (rank : 15)
Query Neighborhood Hits	104	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_HUMAN
NC score	0.318571 (rank : 24)	θ value	9.59137e-10 (rank : 17)
Query Neighborhood Hits	104	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

TRPV3_MOUSE
NC score	0.212980 (rank : 25)	θ value	0.0193708 (rank : 29)
Query Neighborhood Hits	104	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.212401 (rank : 26)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	104	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

NUDT9_MOUSE
NC score	0.155964 (rank : 27)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	104	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_HUMAN
NC score	0.154602 (rank : 28)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	104	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

TRPV6_HUMAN
NC score	0.147908 (rank : 29)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	104	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV1_HUMAN
NC score	0.142636 (rank : 30)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	104	Target Neighborhood Hits	184	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

PK2L1_HUMAN
NC score	0.138072 (rank : 31)	θ value	0.000786445 (rank : 23)
Query Neighborhood Hits	104	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPV1_MOUSE
NC score	0.136525 (rank : 32)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	104	Target Neighborhood Hits	189	Shared Neighborhood Hits	34
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV6_MOUSE
NC score	0.132679 (rank : 33)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	104	Target Neighborhood Hits	284	Shared Neighborhood Hits	37
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV4_HUMAN
NC score	0.132186 (rank : 34)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	104	Target Neighborhood Hits	150	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_HUMAN
NC score	0.129181 (rank : 35)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	104	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV5_MOUSE
NC score	0.124194 (rank : 36)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	104	Target Neighborhood Hits	278	Shared Neighborhood Hits	38
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

NUD9P_HUMAN
NC score	0.117929 (rank : 37)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	104	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

TRPV4_MOUSE
NC score	0.117652 (rank : 38)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	104	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

PK2L2_MOUSE
NC score	0.116111 (rank : 39)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	104	Target Neighborhood Hits	84	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_HUMAN
NC score	0.099600 (rank : 40)	θ value	0.0431538 (rank : 31)
Query Neighborhood Hits	104	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV2_MOUSE
NC score	0.097371 (rank : 41)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	104	Target Neighborhood Hits	111	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV2_HUMAN
NC score	0.076152 (rank : 42)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	104	Target Neighborhood Hits	130	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PKD2_HUMAN
NC score	0.073989 (rank : 43)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	104	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
NC score	0.068312 (rank : 44)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	104	Target Neighborhood Hits	99	Shared Neighborhood Hits	20
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

ACINU_HUMAN
NC score	0.044629 (rank : 45)	θ value	0.0252991 (rank : 30)
Query Neighborhood Hits	104	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

PCNT_MOUSE
NC score	0.043550 (rank : 46)	θ value	0.00869519 (rank : 27)
Query Neighborhood Hits	104	Target Neighborhood Hits	1207	Shared Neighborhood Hits	34
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

AKAP9_HUMAN
NC score	0.036876 (rank : 47)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	104	Target Neighborhood Hits	1710	Shared Neighborhood Hits	44
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

LUZP1_MOUSE
NC score	0.036778 (rank : 48)	θ value	0.0193708 (rank : 28)
Query Neighborhood Hits	104	Target Neighborhood Hits	940	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CCD47_HUMAN
NC score	0.032749 (rank : 49)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	104	Target Neighborhood Hits	119	Shared Neighborhood Hits	5
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

CC47_MOUSE
NC score	0.029192 (rank : 50)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	104	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

LUZP1_HUMAN
NC score	0.028145 (rank : 51)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	104	Target Neighborhood Hits	739	Shared Neighborhood Hits	26
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

RGS1_MOUSE
NC score	0.028088 (rank : 52)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	104	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JL25, Q3TBD1, Q3TC18, Q3TD56	Gene names	Rgs1
Domain Architecture
Description	Regulator of G-protein signaling 1 (RGS1).

TRAK2_HUMAN
NC score	0.027667 (rank : 53)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	104	Target Neighborhood Hits	476	Shared Neighborhood Hits	22
SwissProt Accessions	O60296, Q8WVH7, Q96NS2, Q9C0K5, Q9C0K6	Gene names	TRAK2, ALS2CR3, KIAA0549
Domain Architecture
Description	Trafficking kinesin-binding protein 2 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein).

ACINU_MOUSE
NC score	0.026828 (rank : 54)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	104	Target Neighborhood Hits	712	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LMAN1_MOUSE
NC score	0.026817 (rank : 55)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	104	Target Neighborhood Hits	87	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D0F3	Gene names	Lman1, Ergic53
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (p58).

LMNA_MOUSE
NC score	0.025629 (rank : 56)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	104	Target Neighborhood Hits	661	Shared Neighborhood Hits	27
SwissProt Accessions	P48678, P11516, P97859, Q3TIH0, Q3TTS8, Q3UCA0, Q3UCJ8, Q91WF2, Q9DC21	Gene names	Lmna, Lmn1
Domain Architecture
Description	Lamin-A/C.

UBXD2_HUMAN
NC score	0.025577 (rank : 57)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	104	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q92575, Q8IYM5	Gene names	UBXD2, KIAA0242, UBXDC1
Domain Architecture
Description	UBX domain-containing protein 2.

LMNA_HUMAN
NC score	0.025491 (rank : 58)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	104	Target Neighborhood Hits	653	Shared Neighborhood Hits	27
SwissProt Accessions	P02545, P02546, Q969I8, Q96JA2	Gene names	LMNA, LMN1
Domain Architecture
Description	Lamin-A/C (70 kDa lamin) (NY-REN-32 antigen).

BRD8_HUMAN
NC score	0.023460 (rank : 59)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	104	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

TXD11_HUMAN
NC score	0.022219 (rank : 60)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	104	Target Neighborhood Hits	402	Shared Neighborhood Hits	15
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

SYNE1_HUMAN
NC score	0.021867 (rank : 61)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	104	Target Neighborhood Hits	1484	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

PROM1_MOUSE
NC score	0.020697 (rank : 62)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	104	Target Neighborhood Hits	77	Shared Neighborhood Hits	8
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

UBXD2_MOUSE
NC score	0.020330 (rank : 63)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	104	Target Neighborhood Hits	183	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VCH8, Q8BW17	Gene names	Ubxd2, Ubxdc1
Domain Architecture
Description	UBX domain-containing protein 2.

RBM25_HUMAN
NC score	0.020222 (rank : 64)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	104	Target Neighborhood Hits	682	Shared Neighborhood Hits	20
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

SM1L2_HUMAN
NC score	0.019433 (rank : 65)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	104	Target Neighborhood Hits	1019	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

LMAN1_HUMAN
NC score	0.019395 (rank : 66)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	104	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	P49257, Q12895, Q8N5I7, Q9UQG1, Q9UQG2, Q9UQG3, Q9UQG4, Q9UQG5, Q9UQG6, Q9UQG7, Q9UQG8, Q9UQG9, Q9UQH0, Q9UQH1, Q9UQH2	Gene names	LMAN1, ERGIC53, F5F8D
Domain Architecture
Description	ERGIC-53 protein precursor (ER-Golgi intermediate compartment 53 kDa protein) (Lectin, mannose-binding 1) (Gp58) (Intracellular mannose- specific lectin MR60).

CNGA1_HUMAN
NC score	0.019098 (rank : 67)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	104	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

RAI14_HUMAN
NC score	0.019084 (rank : 68)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	104	Target Neighborhood Hits	1367	Shared Neighborhood Hits	54
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

CING_HUMAN
NC score	0.018458 (rank : 69)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	104	Target Neighborhood Hits	1275	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

EEA1_HUMAN
NC score	0.018289 (rank : 70)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	104	Target Neighborhood Hits	1796	Shared Neighborhood Hits	45
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGB1_HUMAN
NC score	0.018090 (rank : 71)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	104	Target Neighborhood Hits	2297	Shared Neighborhood Hits	44
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

BRD8_MOUSE
NC score	0.017844 (rank : 72)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	104	Target Neighborhood Hits	422	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

TXD11_MOUSE
NC score	0.016981 (rank : 73)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	104	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

CKAP4_HUMAN
NC score	0.016312 (rank : 74)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	104	Target Neighborhood Hits	592	Shared Neighborhood Hits	25
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

MCLN2_HUMAN
NC score	0.016310 (rank : 75)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	104	Target Neighborhood Hits	23	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZK6, Q8N9R3	Gene names	MCOLN2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

BPAEA_HUMAN
NC score	0.016304 (rank : 76)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	104	Target Neighborhood Hits	1369	Shared Neighborhood Hits	39
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENPF_HUMAN
NC score	0.014790 (rank : 77)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	104	Target Neighborhood Hits	1932	Shared Neighborhood Hits	42
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

TPR_HUMAN
NC score	0.014763 (rank : 78)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	104	Target Neighborhood Hits	1921	Shared Neighborhood Hits	42
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCDC6_HUMAN
NC score	0.014693 (rank : 79)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	104	Target Neighborhood Hits	723	Shared Neighborhood Hits	29
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

STAT1_HUMAN
NC score	0.014686 (rank : 80)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	104	Target Neighborhood Hits	128	Shared Neighborhood Hits	14
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

KIF3B_HUMAN
NC score	0.014283 (rank : 81)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	104	Target Neighborhood Hits	540	Shared Neighborhood Hits	23
SwissProt Accessions	O15066	Gene names	KIF3B, KIAA0359
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) (HH0048).

EEA1_MOUSE
NC score	0.013222 (rank : 82)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	104	Target Neighborhood Hits	1637	Shared Neighborhood Hits	40
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

KIF3B_MOUSE
NC score	0.013096 (rank : 83)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	104	Target Neighborhood Hits	533	Shared Neighborhood Hits	22
SwissProt Accessions	Q61771	Gene names	Kif3b
Domain Architecture
Description	Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B).

PHF12_MOUSE
NC score	0.012915 (rank : 84)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	104	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

GCC2_MOUSE
NC score	0.012868 (rank : 85)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	104	Target Neighborhood Hits	1619	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA4_MOUSE
NC score	0.012823 (rank : 86)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	104	Target Neighborhood Hits	1939	Shared Neighborhood Hits	44
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HOOK1_HUMAN
NC score	0.012234 (rank : 87)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	104	Target Neighborhood Hits	942	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

MYH7_HUMAN
NC score	0.012118 (rank : 88)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	104	Target Neighborhood Hits	1559	Shared Neighborhood Hits	36
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

DIAP3_HUMAN
NC score	0.011665 (rank : 89)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	104	Target Neighborhood Hits	209	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DEMA_MOUSE
NC score	0.010956 (rank : 90)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	104	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WV69	Gene names	Epb49, Epb4.9
Domain Architecture
Description	Dematin (Erythrocyte membrane protein band 4.9).

SENP1_MOUSE
NC score	0.010822 (rank : 91)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	104	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P59110	Gene names	Senp1
Domain Architecture
Description	Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1).

CL011_MOUSE
NC score	0.010354 (rank : 92)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	104	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q8QZV7, Q99JT8	Gene names
Domain Architecture	No domain graphic available
Description	Protein C12orf11 homolog.

RCOR2_MOUSE
NC score	0.010116 (rank : 93)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	104	Target Neighborhood Hits	107	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

MYST4_MOUSE
NC score	0.009879 (rank : 94)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	104	Target Neighborhood Hits	416	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

LAMA2_MOUSE
NC score	0.009671 (rank : 95)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	104	Target Neighborhood Hits	1198	Shared Neighborhood Hits	25
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LIPS_MOUSE
NC score	0.009212 (rank : 96)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	104	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	P54310, P97866, Q3TE34, Q6GU16	Gene names	Lipe
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

AT1B1_HUMAN
NC score	0.009160 (rank : 97)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	104	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P05026, Q5TGZ3	Gene names	ATP1B1, ATP1B
Domain Architecture
Description	Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium- dependent ATPase beta-1 subunit).

UBP8_HUMAN
NC score	0.009159 (rank : 98)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	104	Target Neighborhood Hits	751	Shared Neighborhood Hits	26
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

RCOR2_HUMAN
NC score	0.008748 (rank : 99)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	104	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

P73_HUMAN
NC score	0.008586 (rank : 100)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	104	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	O15350, O15351, Q5TBV5, Q5TBV6, Q8NHW9, Q8TDY5, Q8TDY6, Q9NTK8	Gene names	TP73, P73
Domain Architecture
Description	Tumor protein p73 (p53-like transcription factor) (p53-related protein).

DIAP2_MOUSE
NC score	0.008408 (rank : 101)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	104	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

SH3G1_HUMAN
NC score	0.007916 (rank : 102)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	104	Target Neighborhood Hits	307	Shared Neighborhood Hits	7
SwissProt Accessions	Q99961, Q99668	Gene names	SH3GL1, CNSA1, SH3D2B
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (Extra eleven-nineteen leukemia fusion gene) (EEN) (EEN fusion partner of MLL).

S4A11_HUMAN
NC score	0.007717 (rank : 103)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	104	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NBS3, Q9BXF4, Q9NTW9	Gene names	SLC4A11, BTR1
Domain Architecture
Description	Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Solute carrier family 4 member 11).

NOVA2_HUMAN
NC score	0.007160 (rank : 104)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	104	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNW9, O43267, Q9UEA1	Gene names	NOVA2, ANOVA, NOVA3
Domain Architecture
Description	RNA-binding protein Nova-2 (Neuro-oncological ventral antigen 2) (Astrocytic NOVA1-like RNA-binding protein).

CP7B1_MOUSE
NC score	0.006899 (rank : 105)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	104	Target Neighborhood Hits	106	Shared Neighborhood Hits	4
SwissProt Accessions	Q60991	Gene names	Cyp7b1
Domain Architecture
Description	Cytochrome P450 7B1 (EC 1.14.13.100) (25-hydroxycholesterol 7-alpha- hydroxylase) (Oxysterol 7-alpha-hydroxylase) (HCT-1).

SH3G1_MOUSE
NC score	0.006309 (rank : 106)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	104	Target Neighborhood Hits	291	Shared Neighborhood Hits	7
SwissProt Accessions	Q62419	Gene names	Sh3gl1, Sh3d2b
Domain Architecture
Description	SH3-containing GRB2-like protein 1 (Endophilin-2) (Endophilin-A2) (SH3 domain protein 2B) (SH3p8).

3BP1_MOUSE
NC score	0.003908 (rank : 107)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	104	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

OR2H1_HUMAN
NC score	-0.003080 (rank : 108)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	104	Target Neighborhood Hits	755	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZK4, O43629, O43661, O43662, Q9GZK9	Gene names	OR2H1, OR2H6, OR2H8
Domain Architecture
Description	Olfactory receptor 2H1 (Hs6M1-16) (Olfactory receptor 6-2) (OR6-2) (OLFR42A-9004.14/9026.2).

ZN548_HUMAN
NC score	-0.003664 (rank : 109)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	104	Target Neighborhood Hits	739	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEK5, Q96M05	Gene names	ZNF548
Domain Architecture	No domain graphic available
Description	Zinc finger protein 548.