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Network neighborhood for query Sequence : TRPC5_HUMAN

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TRPC5_HUMAN
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPC4_HUMAN
θ value	0 (rank : 1)	NC score	0.990147 (rank : 3)
Query Neighborhood Hits	122	Target Neighborhood Hits	140	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	0 (rank : 2)	NC score	0.989897 (rank : 4)
Query Neighborhood Hits	122	Target Neighborhood Hits	141	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	0 (rank : 4)	NC score	0.999097 (rank : 2)
Query Neighborhood Hits	122	Target Neighborhood Hits	124	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC1_HUMAN
θ value	4.1007e-178 (rank : 5)	NC score	0.962708 (rank : 5)
Query Neighborhood Hits	122	Target Neighborhood Hits	91	Shared Neighborhood Hits	54
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	1.55827e-177 (rank : 6)	NC score	0.962613 (rank : 6)
Query Neighborhood Hits	122	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC3_HUMAN
θ value	6.17048e-150 (rank : 7)	NC score	0.947338 (rank : 9)
Query Neighborhood Hits	122	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	2.19465e-147 (rank : 8)	NC score	0.948531 (rank : 7)
Query Neighborhood Hits	122	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_HUMAN
θ value	4.90052e-139 (rank : 9)	NC score	0.940017 (rank : 13)
Query Neighborhood Hits	122	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	1.74296e-136 (rank : 10)	NC score	0.941500 (rank : 11)
Query Neighborhood Hits	122	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	2.20485e-131 (rank : 11)	NC score	0.940764 (rank : 12)
Query Neighborhood Hits	122	Target Neighborhood Hits	123	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	3.76091e-131 (rank : 12)	NC score	0.941940 (rank : 10)
Query Neighborhood Hits	122	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC2_MOUSE
θ value	1.18001e-100 (rank : 13)	NC score	0.947630 (rank : 8)
Query Neighborhood Hits	122	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPM8_HUMAN
θ value	1.42661e-21 (rank : 14)	NC score	0.576242 (rank : 15)
Query Neighborhood Hits	122	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
θ value	1.2077e-20 (rank : 15)	NC score	0.578442 (rank : 14)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM6_MOUSE
θ value	1.68911e-14 (rank : 16)	NC score	0.470178 (rank : 19)
Query Neighborhood Hits	122	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM2_HUMAN
θ value	2.88119e-14 (rank : 17)	NC score	0.492399 (rank : 16)
Query Neighborhood Hits	122	Target Neighborhood Hits	64	Shared Neighborhood Hits	33
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM7_MOUSE
θ value	2.88119e-14 (rank : 18)	NC score	0.477218 (rank : 17)
Query Neighborhood Hits	122	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
θ value	1.86753e-13 (rank : 19)	NC score	0.475208 (rank : 18)
Query Neighborhood Hits	122	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM2_MOUSE
θ value	9.26847e-13 (rank : 20)	NC score	0.466929 (rank : 20)
Query Neighborhood Hits	122	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM6_HUMAN
θ value	1.2105e-12 (rank : 21)	NC score	0.446853 (rank : 21)
Query Neighborhood Hits	122	Target Neighborhood Hits	91	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM3_HUMAN
θ value	1.06045e-08 (rank : 22)	NC score	0.400876 (rank : 22)
Query Neighborhood Hits	122	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV1_MOUSE
θ value	4.0297e-08 (rank : 23)	NC score	0.294764 (rank : 25)
Query Neighborhood Hits	122	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
θ value	2.88788e-06 (rank : 24)	NC score	0.289665 (rank : 26)
Query Neighborhood Hits	122	Target Neighborhood Hits	184	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV3_HUMAN
θ value	4.92598e-06 (rank : 25)	NC score	0.336674 (rank : 23)
Query Neighborhood Hits	122	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	1.09739e-05 (rank : 26)	NC score	0.316984 (rank : 24)
Query Neighborhood Hits	122	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV5_MOUSE
θ value	4.1701e-05 (rank : 27)	NC score	0.253627 (rank : 27)
Query Neighborhood Hits	122	Target Neighborhood Hits	278	Shared Neighborhood Hits	94
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_MOUSE
θ value	0.00035302 (rank : 28)	NC score	0.236823 (rank : 30)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	93
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV2_HUMAN
θ value	0.000461057 (rank : 29)	NC score	0.195140 (rank : 35)
Query Neighborhood Hits	122	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV6_HUMAN
θ value	0.00102713 (rank : 30)	NC score	0.245767 (rank : 28)
Query Neighborhood Hits	122	Target Neighborhood Hits	262	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV2_MOUSE
θ value	0.00665767 (rank : 31)	NC score	0.198286 (rank : 34)
Query Neighborhood Hits	122	Target Neighborhood Hits	111	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

ANKY2_MOUSE
θ value	0.00869519 (rank : 32)	NC score	0.130305 (rank : 40)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR21_HUMAN
θ value	0.0193708 (rank : 33)	NC score	0.085451 (rank : 61)
Query Neighborhood Hits	122	Target Neighborhood Hits	864	Shared Neighborhood Hits	85
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR35_HUMAN
θ value	0.0193708 (rank : 34)	NC score	0.073894 (rank : 84)
Query Neighborhood Hits	122	Target Neighborhood Hits	784	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

PKD2_MOUSE
θ value	0.0252991 (rank : 35)	NC score	0.161759 (rank : 38)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

POT15_HUMAN
θ value	0.0252991 (rank : 36)	NC score	0.083407 (rank : 66)
Query Neighborhood Hits	122	Target Neighborhood Hits	893	Shared Neighborhood Hits	84
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TRPV5_HUMAN
θ value	0.0252991 (rank : 37)	NC score	0.218240 (rank : 32)
Query Neighborhood Hits	122	Target Neighborhood Hits	261	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANKY2_HUMAN
θ value	0.0330416 (rank : 38)	NC score	0.106877 (rank : 44)
Query Neighborhood Hits	122	Target Neighborhood Hits	306	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

PKD2_HUMAN
θ value	0.0330416 (rank : 39)	NC score	0.162770 (rank : 37)
Query Neighborhood Hits	122	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

ANK1_HUMAN
θ value	0.0431538 (rank : 40)	NC score	0.113066 (rank : 42)
Query Neighborhood Hits	122	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	0.0431538 (rank : 41)	NC score	0.112810 (rank : 43)
Query Neighborhood Hits	122	Target Neighborhood Hits	430	Shared Neighborhood Hits	81
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

MPP8_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.067326 (rank : 96)
Query Neighborhood Hits	122	Target Neighborhood Hits	948	Shared Neighborhood Hits	76
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

TRPV4_HUMAN
θ value	0.0431538 (rank : 43)	NC score	0.243226 (rank : 29)
Query Neighborhood Hits	122	Target Neighborhood Hits	150	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ACBD6_MOUSE
θ value	0.0563607 (rank : 44)	NC score	0.119360 (rank : 41)
Query Neighborhood Hits	122	Target Neighborhood Hits	305	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

CTTB2_HUMAN
θ value	0.0563607 (rank : 45)	NC score	0.093139 (rank : 49)
Query Neighborhood Hits	122	Target Neighborhood Hits	1061	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ASZ1_MOUSE
θ value	0.0736092 (rank : 46)	NC score	0.083351 (rank : 67)
Query Neighborhood Hits	122	Target Neighborhood Hits	319	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TRPV4_MOUSE
θ value	0.0736092 (rank : 47)	NC score	0.225483 (rank : 31)
Query Neighborhood Hits	122	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CSKI1_MOUSE
θ value	0.0961366 (rank : 48)	NC score	0.069647 (rank : 91)
Query Neighborhood Hits	122	Target Neighborhood Hits	1031	Shared Neighborhood Hits	71
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RN5A_MOUSE
θ value	0.0961366 (rank : 49)	NC score	0.089512 (rank : 56)
Query Neighborhood Hits	122	Target Neighborhood Hits	899	Shared Neighborhood Hits	84
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

TFAM_HUMAN
θ value	0.0961366 (rank : 50)	NC score	0.038197 (rank : 172)
Query Neighborhood Hits	122	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

CSKI1_HUMAN
θ value	0.125558 (rank : 51)	NC score	0.069544 (rank : 92)
Query Neighborhood Hits	122	Target Neighborhood Hits	997	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TNKS1_HUMAN
θ value	0.125558 (rank : 52)	NC score	0.085402 (rank : 62)
Query Neighborhood Hits	122	Target Neighborhood Hits	477	Shared Neighborhood Hits	78
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANR44_HUMAN
θ value	0.163984 (rank : 53)	NC score	0.084763 (rank : 64)
Query Neighborhood Hits	122	Target Neighborhood Hits	318	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

PK2L2_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.141764 (rank : 39)
Query Neighborhood Hits	122	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

SC10A_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.033452 (rank : 174)
Query Neighborhood Hits	122	Target Neighborhood Hits	116	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

ANKS6_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.087746 (rank : 59)
Query Neighborhood Hits	122	Target Neighborhood Hits	411	Shared Neighborhood Hits	74
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR26_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.062409 (rank : 107)
Query Neighborhood Hits	122	Target Neighborhood Hits	1614	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR50_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.086429 (rank : 60)
Query Neighborhood Hits	122	Target Neighborhood Hits	361	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

SC10A_MOUSE
θ value	0.21417 (rank : 59)	NC score	0.030703 (rank : 176)
Query Neighborhood Hits	122	Target Neighborhood Hits	107	Shared Neighborhood Hits	22
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

TR143_MOUSE
θ value	0.21417 (rank : 60)	NC score	0.028132 (rank : 177)
Query Neighborhood Hits	122	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQB9, Q2NL43	Gene names	Tas2r143, T2r36, Tas2r43
Domain Architecture
Description	Taste receptor type 2 member 143 (T2R143) (Taste receptor type 2 member 43) (T2R43) (mT2R36).

AN36B_HUMAN
θ value	0.279714 (rank : 61)	NC score	0.099079 (rank : 46)
Query Neighborhood Hits	122	Target Neighborhood Hits	294	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

PK2L1_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.202660 (rank : 33)
Query Neighborhood Hits	122	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

IF2P_HUMAN
θ value	0.365318 (rank : 63)	NC score	0.025373 (rank : 179)
Query Neighborhood Hits	122	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

ANKR7_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.078089 (rank : 74)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	69
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR52_HUMAN
θ value	0.47712 (rank : 65)	NC score	0.092913 (rank : 50)
Query Neighborhood Hits	122	Target Neighborhood Hits	322	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	0.47712 (rank : 66)	NC score	0.092578 (rank : 51)
Query Neighborhood Hits	122	Target Neighborhood Hits	318	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

PK2L2_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.173846 (rank : 36)
Query Neighborhood Hits	122	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

POTE8_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.090650 (rank : 55)
Query Neighborhood Hits	122	Target Neighborhood Hits	337	Shared Neighborhood Hits	77
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

PRP4B_MOUSE
θ value	0.62314 (rank : 69)	NC score	0.003354 (rank : 193)
Query Neighborhood Hits	122	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TNKS2_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.082064 (rank : 68)
Query Neighborhood Hits	122	Target Neighborhood Hits	361	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

F120A_HUMAN
θ value	1.06291 (rank : 71)	NC score	0.015317 (rank : 183)
Query Neighborhood Hits	122	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

GP156_MOUSE
θ value	1.06291 (rank : 72)	NC score	0.031847 (rank : 175)
Query Neighborhood Hits	122	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

RAI1_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.012712 (rank : 185)
Query Neighborhood Hits	122	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TOM70_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.016601 (rank : 182)
Query Neighborhood Hits	122	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.017111 (rank : 181)
Query Neighborhood Hits	122	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

ASB14_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.057871 (rank : 114)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

EHMT1_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.091922 (rank : 52)
Query Neighborhood Hits	122	Target Neighborhood Hits	417	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SFRS6_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.007494 (rank : 190)
Query Neighborhood Hits	122	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

ACBD6_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.095624 (rank : 47)
Query Neighborhood Hits	122	Target Neighborhood Hits	304	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

AN13A_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.076496 (rank : 76)
Query Neighborhood Hits	122	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANFY1_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.076380 (rank : 77)
Query Neighborhood Hits	122	Target Neighborhood Hits	480	Shared Neighborhood Hits	79
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BARD1_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.073162 (rank : 86)
Query Neighborhood Hits	122	Target Neighborhood Hits	427	Shared Neighborhood Hits	69
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANK3_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.089374 (rank : 57)
Query Neighborhood Hits	122	Target Neighborhood Hits	853	Shared Neighborhood Hits	88
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANKK1_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.041725 (rank : 170)
Query Neighborhood Hits	122	Target Neighborhood Hits	1075	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ASZ1_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.076093 (rank : 78)
Query Neighborhood Hits	122	Target Neighborhood Hits	341	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

SYCP1_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.012385 (rank : 186)
Query Neighborhood Hits	122	Target Neighborhood Hits	1313	Shared Neighborhood Hits	29
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

BCOR_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.079467 (rank : 72)
Query Neighborhood Hits	122	Target Neighborhood Hits	609	Shared Neighborhood Hits	76
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.080469 (rank : 70)
Query Neighborhood Hits	122	Target Neighborhood Hits	521	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

GP156_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.024931 (rank : 180)
Query Neighborhood Hits	122	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

PRP4B_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.001382 (rank : 195)
Query Neighborhood Hits	122	Target Neighborhood Hits	1030	Shared Neighborhood Hits	15
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RAI14_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.067449 (rank : 95)
Query Neighborhood Hits	122	Target Neighborhood Hits	1367	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

AKAP9_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.010635 (rank : 188)
Query Neighborhood Hits	122	Target Neighborhood Hits	1710	Shared Neighborhood Hits	36
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR15_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.072504 (rank : 87)
Query Neighborhood Hits	122	Target Neighborhood Hits	478	Shared Neighborhood Hits	79
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ASB2_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.067628 (rank : 94)
Query Neighborhood Hits	122	Target Neighborhood Hits	309	Shared Neighborhood Hits	69
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CN145_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.010256 (rank : 189)
Query Neighborhood Hits	122	Target Neighborhood Hits	916	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CTRO_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.000458 (rank : 196)
Query Neighborhood Hits	122	Target Neighborhood Hits	2344	Shared Neighborhood Hits	31
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

POT14_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.074640 (rank : 83)
Query Neighborhood Hits	122	Target Neighborhood Hits	403	Shared Neighborhood Hits	66
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

RIPK4_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.043289 (rank : 167)
Query Neighborhood Hits	122	Target Neighborhood Hits	1094	Shared Neighborhood Hits	80
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

AN13B_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.043165 (rank : 168)
Query Neighborhood Hits	122	Target Neighborhood Hits	265	Shared Neighborhood Hits	61
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.043161 (rank : 169)
Query Neighborhood Hits	122	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

BARD1_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.085129 (rank : 63)
Query Neighborhood Hits	122	Target Neighborhood Hits	411	Shared Neighborhood Hits	69
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

BCL3_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.066839 (rank : 97)
Query Neighborhood Hits	122	Target Neighborhood Hits	324	Shared Neighborhood Hits	72
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

CT026_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.037585 (rank : 173)
Query Neighborhood Hits	122	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

EHMT2_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.078335 (rank : 73)
Query Neighborhood Hits	122	Target Neighborhood Hits	498	Shared Neighborhood Hits	75
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

MYH9_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.004196 (rank : 191)
Query Neighborhood Hits	122	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.003900 (rank : 192)
Query Neighborhood Hits	122	Target Neighborhood Hits	1829	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NIN_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.015042 (rank : 184)
Query Neighborhood Hits	122	Target Neighborhood Hits	1376	Shared Neighborhood Hits	31
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

UACA_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.045222 (rank : 166)
Query Neighborhood Hits	122	Target Neighborhood Hits	1622	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UACA_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.038722 (rank : 171)
Query Neighborhood Hits	122	Target Neighborhood Hits	1620	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AN30A_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.056412 (rank : 119)
Query Neighborhood Hits	122	Target Neighborhood Hits	1119	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

AN36A_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.059606 (rank : 112)
Query Neighborhood Hits	122	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANKS6_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.081743 (rank : 69)
Query Neighborhood Hits	122	Target Neighborhood Hits	435	Shared Neighborhood Hits	74
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR28_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.069045 (rank : 93)
Query Neighborhood Hits	122	Target Neighborhood Hits	314	Shared Neighborhood Hits	74
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR38_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.055024 (rank : 128)
Query Neighborhood Hits	122	Target Neighborhood Hits	443	Shared Neighborhood Hits	72
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

E41L2_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.002321 (rank : 194)
Query Neighborhood Hits	122	Target Neighborhood Hits	459	Shared Neighborhood Hits	13
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

EEA1_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.011250 (rank : 187)
Query Neighborhood Hits	122	Target Neighborhood Hits	1637	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

ROCK2_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.000276 (rank : 197)
Query Neighborhood Hits	122	Target Neighborhood Hits	2073	Shared Neighborhood Hits	30
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	6.88961 (rank : 118)	NC score	-0.000283 (rank : 198)
Query Neighborhood Hits	122	Target Neighborhood Hits	2072	Shared Neighborhood Hits	27
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

A20A2_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.050623 (rank : 159)
Query Neighborhood Hits	122	Target Neighborhood Hits	716	Shared Neighborhood Hits	74
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANKS1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.091710 (rank : 54)
Query Neighborhood Hits	122	Target Neighborhood Hits	438	Shared Neighborhood Hits	76
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

CAC1B_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.026801 (rank : 178)
Query Neighborhood Hits	122	Target Neighborhood Hits	257	Shared Neighborhood Hits	16
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRPA1_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.103589 (rank : 45)
Query Neighborhood Hits	122	Target Neighborhood Hits	339	Shared Neighborhood Hits	87
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ANFY1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.057134 (rank : 115)
Query Neighborhood Hits	122	Target Neighborhood Hits	480	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANK2_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.074724 (rank : 82)
Query Neighborhood Hits	122	Target Neighborhood Hits	1615	Shared Neighborhood Hits	92
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANKR1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.055668 (rank : 125)
Query Neighborhood Hits	122	Target Neighborhood Hits	308	Shared Neighborhood Hits	63
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.070309 (rank : 89)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR2_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.053290 (rank : 140)
Query Neighborhood Hits	122	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANKR2_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.052779 (rank : 142)
Query Neighborhood Hits	122	Target Neighborhood Hits	312	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR6_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.056876 (rank : 117)
Query Neighborhood Hits	122	Target Neighborhood Hits	439	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANKS1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.084437 (rank : 65)
Query Neighborhood Hits	122	Target Neighborhood Hits	453	Shared Neighborhood Hits	71
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANKS3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.050870 (rank : 157)
Query Neighborhood Hits	122	Target Neighborhood Hits	355	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR16_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.054984 (rank : 129)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR18_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.054096 (rank : 137)
Query Neighborhood Hits	122	Target Neighborhood Hits	1106	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR19_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.062083 (rank : 109)
Query Neighborhood Hits	122	Target Neighborhood Hits	276	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR22_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.050091 (rank : 165)
Query Neighborhood Hits	122	Target Neighborhood Hits	243	Shared Neighborhood Hits	58
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR25_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.058089 (rank : 113)
Query Neighborhood Hits	122	Target Neighborhood Hits	398	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR28_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.070055 (rank : 90)
Query Neighborhood Hits	122	Target Neighborhood Hits	314	Shared Neighborhood Hits	74
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR29_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.075849 (rank : 80)
Query Neighborhood Hits	122	Target Neighborhood Hits	294	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR32_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.051341 (rank : 154)
Query Neighborhood Hits	122	Target Neighborhood Hits	270	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR32_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.054900 (rank : 131)
Query Neighborhood Hits	122	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR33_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.050538 (rank : 160)
Query Neighborhood Hits	122	Target Neighborhood Hits	215	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR33_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.052180 (rank : 147)
Query Neighborhood Hits	122	Target Neighborhood Hits	225	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR39_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.051604 (rank : 150)
Query Neighborhood Hits	122	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.050493 (rank : 161)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR46_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.055313 (rank : 127)
Query Neighborhood Hits	122	Target Neighborhood Hits	281	Shared Neighborhood Hits	66
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR46_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.052746 (rank : 143)
Query Neighborhood Hits	122	Target Neighborhood Hits	274	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR49_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.054050 (rank : 138)
Query Neighborhood Hits	122	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANRA2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.055389 (rank : 126)
Query Neighborhood Hits	122	Target Neighborhood Hits	288	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.055856 (rank : 124)
Query Neighborhood Hits	122	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB15_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.065207 (rank : 100)
Query Neighborhood Hits	122	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB15_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.056103 (rank : 121)
Query Neighborhood Hits	122	Target Neighborhood Hits	292	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB16_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.050173 (rank : 163)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	62
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB16_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.050906 (rank : 156)
Query Neighborhood Hits	122	Target Neighborhood Hits	306	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.064474 (rank : 102)
Query Neighborhood Hits	122	Target Neighborhood Hits	291	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.073256 (rank : 85)
Query Neighborhood Hits	122	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB2_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.063515 (rank : 106)
Query Neighborhood Hits	122	Target Neighborhood Hits	321	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB3_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.088694 (rank : 58)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB3_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.080394 (rank : 71)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ASB6_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.054019 (rank : 139)
Query Neighborhood Hits	122	Target Neighborhood Hits	256	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB6_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.054162 (rank : 136)
Query Neighborhood Hits	122	Target Neighborhood Hits	264	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ASB7_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.056052 (rank : 122)
Query Neighborhood Hits	122	Target Neighborhood Hits	296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.056023 (rank : 123)
Query Neighborhood Hits	122	Target Neighborhood Hits	296	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB8_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.052660 (rank : 144)
Query Neighborhood Hits	122	Target Neighborhood Hits	294	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.051691 (rank : 149)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BCL3_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.056877 (rank : 116)
Query Neighborhood Hits	122	Target Neighborhood Hits	388	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

CDN2D_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.051202 (rank : 155)
Query Neighborhood Hits	122	Target Neighborhood Hits	268	Shared Neighborhood Hits	63
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CLPB_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.050491 (rank : 162)
Query Neighborhood Hits	122	Target Neighborhood Hits	265	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

CSKI2_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.077124 (rank : 75)
Query Neighborhood Hits	122	Target Neighborhood Hits	747	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CSKI2_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.075938 (rank : 79)
Query Neighborhood Hits	122	Target Neighborhood Hits	812	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CT012_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.056828 (rank : 118)
Query Neighborhood Hits	122	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

EHMT2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.065731 (rank : 98)
Query Neighborhood Hits	122	Target Neighborhood Hits	750	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

FANK1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.063539 (rank : 105)
Query Neighborhood Hits	122	Target Neighborhood Hits	326	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

FANK1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.056128 (rank : 120)
Query Neighborhood Hits	122	Target Neighborhood Hits	325	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

GABP2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.071615 (rank : 88)
Query Neighborhood Hits	122	Target Neighborhood Hits	454	Shared Neighborhood Hits	73
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.074953 (rank : 81)
Query Neighborhood Hits	122	Target Neighborhood Hits	429	Shared Neighborhood Hits	73
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

IKBA_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.054640 (rank : 133)
Query Neighborhood Hits	122	Target Neighborhood Hits	280	Shared Neighborhood Hits	69
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBA_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.054179 (rank : 135)
Query Neighborhood Hits	122	Target Neighborhood Hits	283	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

IKBB_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.052300 (rank : 146)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

IKBB_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.053026 (rank : 141)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	68
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

IKBE_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.050149 (rank : 164)
Query Neighborhood Hits	122	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBE_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.054463 (rank : 134)
Query Neighborhood Hits	122	Target Neighborhood Hits	308	Shared Neighborhood Hits	68
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

INVS_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.063971 (rank : 104)
Query Neighborhood Hits	122	Target Neighborhood Hits	455	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.065225 (rank : 99)
Query Neighborhood Hits	122	Target Neighborhood Hits	609	Shared Neighborhood Hits	73
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

MIB1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.064485 (rank : 101)
Query Neighborhood Hits	122	Target Neighborhood Hits	470	Shared Neighborhood Hits	76
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.064472 (rank : 103)
Query Neighborhood Hits	122	Target Neighborhood Hits	471	Shared Neighborhood Hits	76
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.052551 (rank : 145)
Query Neighborhood Hits	122	Target Neighborhood Hits	438	Shared Neighborhood Hits	68
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

MIB2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.051438 (rank : 152)
Query Neighborhood Hits	122	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MTPN_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.051415 (rank : 153)
Query Neighborhood Hits	122	Target Neighborhood Hits	269	Shared Neighborhood Hits	59
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.051470 (rank : 151)
Query Neighborhood Hits	122	Target Neighborhood Hits	269	Shared Neighborhood Hits	59
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MYPT1_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.050649 (rank : 158)
Query Neighborhood Hits	122	Target Neighborhood Hits	539	Shared Neighborhood Hits	76
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MYPT2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.062401 (rank : 108)
Query Neighborhood Hits	122	Target Neighborhood Hits	707	Shared Neighborhood Hits	77
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PA2G6_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.054664 (rank : 132)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PA2G6_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.061665 (rank : 110)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

POT22_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.060275 (rank : 111)
Query Neighborhood Hits	122	Target Neighborhood Hits	266	Shared Neighborhood Hits	59
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

PSD10_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.054953 (rank : 130)
Query Neighborhood Hits	122	Target Neighborhood Hits	301	Shared Neighborhood Hits	67
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.052007 (rank : 148)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RN5A_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.091789 (rank : 53)
Query Neighborhood Hits	122	Target Neighborhood Hits	608	Shared Neighborhood Hits	76
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

TRPA1_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.094335 (rank : 48)
Query Neighborhood Hits	122	Target Neighborhood Hits	343	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

Hits sorted by NC score

TRPC5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	122	Target Neighborhood Hits	122	Shared Neighborhood Hits	122
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
NC score	0.999097 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	122	Target Neighborhood Hits	124	Shared Neighborhood Hits	113
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC4_HUMAN
NC score	0.990147 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	122	Target Neighborhood Hits	140	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.989897 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	122	Target Neighborhood Hits	141	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC1_HUMAN
NC score	0.962708 (rank : 5)	θ value	4.1007e-178 (rank : 5)
Query Neighborhood Hits	122	Target Neighborhood Hits	91	Shared Neighborhood Hits	54
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
NC score	0.962613 (rank : 6)	θ value	1.55827e-177 (rank : 6)
Query Neighborhood Hits	122	Target Neighborhood Hits	87	Shared Neighborhood Hits	52
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC3_MOUSE
NC score	0.948531 (rank : 7)	θ value	2.19465e-147 (rank : 8)
Query Neighborhood Hits	122	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC2_MOUSE
NC score	0.947630 (rank : 8)	θ value	1.18001e-100 (rank : 13)
Query Neighborhood Hits	122	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_HUMAN
NC score	0.947338 (rank : 9)	θ value	6.17048e-150 (rank : 7)
Query Neighborhood Hits	122	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC7_MOUSE
NC score	0.941940 (rank : 10)	θ value	3.76091e-131 (rank : 12)
Query Neighborhood Hits	122	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC6_MOUSE
NC score	0.941500 (rank : 11)	θ value	1.74296e-136 (rank : 10)
Query Neighborhood Hits	122	Target Neighborhood Hits	171	Shared Neighborhood Hits	71
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
NC score	0.940764 (rank : 12)	θ value	2.20485e-131 (rank : 11)
Query Neighborhood Hits	122	Target Neighborhood Hits	123	Shared Neighborhood Hits	66
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC6_HUMAN
NC score	0.940017 (rank : 13)	θ value	4.90052e-139 (rank : 9)
Query Neighborhood Hits	122	Target Neighborhood Hits	171	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPM8_MOUSE
NC score	0.578442 (rank : 14)	θ value	1.2077e-20 (rank : 15)
Query Neighborhood Hits	122	Target Neighborhood Hits	58	Shared Neighborhood Hits	38
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
NC score	0.576242 (rank : 15)	θ value	1.42661e-21 (rank : 14)
Query Neighborhood Hits	122	Target Neighborhood Hits	65	Shared Neighborhood Hits	40
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_HUMAN
NC score	0.492399 (rank : 16)	θ value	2.88119e-14 (rank : 17)
Query Neighborhood Hits	122	Target Neighborhood Hits	64	Shared Neighborhood Hits	33
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM7_MOUSE
NC score	0.477218 (rank : 17)	θ value	2.88119e-14 (rank : 18)
Query Neighborhood Hits	122	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
NC score	0.475208 (rank : 18)	θ value	1.86753e-13 (rank : 19)
Query Neighborhood Hits	122	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_MOUSE
NC score	0.470178 (rank : 19)	θ value	1.68911e-14 (rank : 16)
Query Neighborhood Hits	122	Target Neighborhood Hits	78	Shared Neighborhood Hits	30
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM2_MOUSE
NC score	0.466929 (rank : 20)	θ value	9.26847e-13 (rank : 20)
Query Neighborhood Hits	122	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM6_HUMAN
NC score	0.446853 (rank : 21)	θ value	1.2105e-12 (rank : 21)
Query Neighborhood Hits	122	Target Neighborhood Hits	91	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM3_HUMAN
NC score	0.400876 (rank : 22)	θ value	1.06045e-08 (rank : 22)
Query Neighborhood Hits	122	Target Neighborhood Hits	121	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV3_HUMAN
NC score	0.336674 (rank : 23)	θ value	4.92598e-06 (rank : 25)
Query Neighborhood Hits	122	Target Neighborhood Hits	198	Shared Neighborhood Hits	82
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.316984 (rank : 24)	θ value	1.09739e-05 (rank : 26)
Query Neighborhood Hits	122	Target Neighborhood Hits	188	Shared Neighborhood Hits	78
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_MOUSE
NC score	0.294764 (rank : 25)	θ value	4.0297e-08 (rank : 23)
Query Neighborhood Hits	122	Target Neighborhood Hits	189	Shared Neighborhood Hits	73
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
NC score	0.289665 (rank : 26)	θ value	2.88788e-06 (rank : 24)
Query Neighborhood Hits	122	Target Neighborhood Hits	184	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV5_MOUSE
NC score	0.253627 (rank : 27)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	122	Target Neighborhood Hits	278	Shared Neighborhood Hits	94
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
NC score	0.245767 (rank : 28)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	122	Target Neighborhood Hits	262	Shared Neighborhood Hits	93
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV4_HUMAN
NC score	0.243226 (rank : 29)	θ value	0.0431538 (rank : 43)
Query Neighborhood Hits	122	Target Neighborhood Hits	150	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV6_MOUSE
NC score	0.236823 (rank : 30)	θ value	0.00035302 (rank : 28)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	93
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV4_MOUSE
NC score	0.225483 (rank : 31)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	122	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_HUMAN
NC score	0.218240 (rank : 32)	θ value	0.0252991 (rank : 37)
Query Neighborhood Hits	122	Target Neighborhood Hits	261	Shared Neighborhood Hits	92
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

PK2L1_HUMAN
NC score	0.202660 (rank : 33)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	122	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPV2_MOUSE
NC score	0.198286 (rank : 34)	θ value	0.00665767 (rank : 31)
Query Neighborhood Hits	122	Target Neighborhood Hits	111	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV2_HUMAN
NC score	0.195140 (rank : 35)	θ value	0.000461057 (rank : 29)
Query Neighborhood Hits	122	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PK2L2_MOUSE
NC score	0.173846 (rank : 36)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	122	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
NC score	0.162770 (rank : 37)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	122	Target Neighborhood Hits	105	Shared Neighborhood Hits	30
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
NC score	0.161759 (rank : 38)	θ value	0.0252991 (rank : 35)
Query Neighborhood Hits	122	Target Neighborhood Hits	99	Shared Neighborhood Hits	25
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L2_HUMAN
NC score	0.141764 (rank : 39)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	122	Target Neighborhood Hits	90	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

ANKY2_MOUSE
NC score	0.130305 (rank : 40)	θ value	0.00869519 (rank : 32)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	68
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ACBD6_MOUSE
NC score	0.119360 (rank : 41)	θ value	0.0563607 (rank : 44)
Query Neighborhood Hits	122	Target Neighborhood Hits	305	Shared Neighborhood Hits	72
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANK1_HUMAN
NC score	0.113066 (rank : 42)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	122	Target Neighborhood Hits	416	Shared Neighborhood Hits	80
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.112810 (rank : 43)	θ value	0.0431538 (rank : 41)
Query Neighborhood Hits	122	Target Neighborhood Hits	430	Shared Neighborhood Hits	81
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANKY2_HUMAN
NC score	0.106877 (rank : 44)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	122	Target Neighborhood Hits	306	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

TRPA1_HUMAN
NC score	0.103589 (rank : 45)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	122	Target Neighborhood Hits	339	Shared Neighborhood Hits	87
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

AN36B_HUMAN
NC score	0.099079 (rank : 46)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	122	Target Neighborhood Hits	294	Shared Neighborhood Hits	76
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ACBD6_HUMAN
NC score	0.095624 (rank : 47)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	122	Target Neighborhood Hits	304	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

TRPA1_MOUSE
NC score	0.094335 (rank : 48)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	122	Target Neighborhood Hits	343	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

CTTB2_HUMAN
NC score	0.093139 (rank : 49)	θ value	0.0563607 (rank : 45)
Query Neighborhood Hits	122	Target Neighborhood Hits	1061	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR52_HUMAN
NC score	0.092913 (rank : 50)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	122	Target Neighborhood Hits	322	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
NC score	0.092578 (rank : 51)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	122	Target Neighborhood Hits	318	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

EHMT1_HUMAN
NC score	0.091922 (rank : 52)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	122	Target Neighborhood Hits	417	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

RN5A_HUMAN
NC score	0.091789 (rank : 53)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	122	Target Neighborhood Hits	608	Shared Neighborhood Hits	76
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANKS1_HUMAN
NC score	0.091710 (rank : 54)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	122	Target Neighborhood Hits	438	Shared Neighborhood Hits	76
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

POTE8_HUMAN
NC score	0.090650 (rank : 55)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	122	Target Neighborhood Hits	337	Shared Neighborhood Hits	77
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

RN5A_MOUSE
NC score	0.089512 (rank : 56)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	122	Target Neighborhood Hits	899	Shared Neighborhood Hits	84
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANK3_HUMAN
NC score	0.089374 (rank : 57)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	122	Target Neighborhood Hits	853	Shared Neighborhood Hits	88
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ASB3_HUMAN
NC score	0.088694 (rank : 58)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKS6_HUMAN
NC score	0.087746 (rank : 59)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	122	Target Neighborhood Hits	411	Shared Neighborhood Hits	74
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR50_HUMAN
NC score	0.086429 (rank : 60)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	122	Target Neighborhood Hits	361	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANR21_HUMAN
NC score	0.085451 (rank : 61)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	122	Target Neighborhood Hits	864	Shared Neighborhood Hits	85
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

TNKS1_HUMAN
NC score	0.085402 (rank : 62)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	122	Target Neighborhood Hits	477	Shared Neighborhood Hits	78
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

BARD1_MOUSE
NC score	0.085129 (rank : 63)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	122	Target Neighborhood Hits	411	Shared Neighborhood Hits	69
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR44_HUMAN
NC score	0.084763 (rank : 64)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	122	Target Neighborhood Hits	318	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANKS1_MOUSE
NC score	0.084437 (rank : 65)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	122	Target Neighborhood Hits	453	Shared Neighborhood Hits	71
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

POT15_HUMAN
NC score	0.083407 (rank : 66)	θ value	0.0252991 (rank : 36)
Query Neighborhood Hits	122	Target Neighborhood Hits	893	Shared Neighborhood Hits	84
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ASZ1_MOUSE
NC score	0.083351 (rank : 67)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	122	Target Neighborhood Hits	319	Shared Neighborhood Hits	64
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TNKS2_HUMAN
NC score	0.082064 (rank : 68)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	122	Target Neighborhood Hits	361	Shared Neighborhood Hits	78
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANKS6_MOUSE
NC score	0.081743 (rank : 69)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	122	Target Neighborhood Hits	435	Shared Neighborhood Hits	74
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

BCOR_MOUSE
NC score	0.080469 (rank : 70)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	122	Target Neighborhood Hits	521	Shared Neighborhood Hits	73
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ASB3_MOUSE
NC score	0.080394 (rank : 71)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	71
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

BCOR_HUMAN
NC score	0.079467 (rank : 72)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	122	Target Neighborhood Hits	609	Shared Neighborhood Hits	76
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

EHMT2_HUMAN
NC score	0.078335 (rank : 73)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	122	Target Neighborhood Hits	498	Shared Neighborhood Hits	75
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANKR7_HUMAN
NC score	0.078089 (rank : 74)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	69
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

CSKI2_HUMAN
NC score	0.077124 (rank : 75)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	122	Target Neighborhood Hits	747	Shared Neighborhood Hits	73
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

AN13A_HUMAN
NC score	0.076496 (rank : 76)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	122	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

ANFY1_MOUSE
NC score	0.076380 (rank : 77)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	122	Target Neighborhood Hits	480	Shared Neighborhood Hits	79
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASZ1_HUMAN
NC score	0.076093 (rank : 78)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	122	Target Neighborhood Hits	341	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

CSKI2_MOUSE
NC score	0.075938 (rank : 79)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	122	Target Neighborhood Hits	812	Shared Neighborhood Hits	74
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR29_HUMAN
NC score	0.075849 (rank : 80)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	122	Target Neighborhood Hits	294	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

GABP2_MOUSE
NC score	0.074953 (rank : 81)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	122	Target Neighborhood Hits	429	Shared Neighborhood Hits	73
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

ANK2_HUMAN
NC score	0.074724 (rank : 82)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	122	Target Neighborhood Hits	1615	Shared Neighborhood Hits	92
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

POT14_HUMAN
NC score	0.074640 (rank : 83)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	122	Target Neighborhood Hits	403	Shared Neighborhood Hits	66
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ANR35_HUMAN
NC score	0.073894 (rank : 84)	θ value	0.0193708 (rank : 34)
Query Neighborhood Hits	122	Target Neighborhood Hits	784	Shared Neighborhood Hits	79
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

ASB1_MOUSE
NC score	0.073256 (rank : 85)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	122	Target Neighborhood Hits	292	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

BARD1_HUMAN
NC score	0.073162 (rank : 86)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	122	Target Neighborhood Hits	427	Shared Neighborhood Hits	69
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR15_HUMAN
NC score	0.072504 (rank : 87)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	122	Target Neighborhood Hits	478	Shared Neighborhood Hits	79
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

GABP2_HUMAN
NC score	0.071615 (rank : 88)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	122	Target Neighborhood Hits	454	Shared Neighborhood Hits	73
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ANKR1_MOUSE
NC score	0.070309 (rank : 89)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	122	Target Neighborhood Hits	316	Shared Neighborhood Hits	68
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANR28_MOUSE
NC score	0.070055 (rank : 90)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	122	Target Neighborhood Hits	314	Shared Neighborhood Hits	74
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

CSKI1_MOUSE
NC score	0.069647 (rank : 91)	θ value	0.0961366 (rank : 48)
Query Neighborhood Hits	122	Target Neighborhood Hits	1031	Shared Neighborhood Hits	71
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_HUMAN
NC score	0.069544 (rank : 92)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	122	Target Neighborhood Hits	997	Shared Neighborhood Hits	71
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR28_HUMAN
NC score	0.069045 (rank : 93)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	122	Target Neighborhood Hits	314	Shared Neighborhood Hits	74
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB2_HUMAN
NC score	0.067628 (rank : 94)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	122	Target Neighborhood Hits	309	Shared Neighborhood Hits	69
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

RAI14_HUMAN
NC score	0.067449 (rank : 95)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	122	Target Neighborhood Hits	1367	Shared Neighborhood Hits	92
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

MPP8_HUMAN
NC score	0.067326 (rank : 96)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	122	Target Neighborhood Hits	948	Shared Neighborhood Hits	76
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

BCL3_HUMAN
NC score	0.066839 (rank : 97)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	122	Target Neighborhood Hits	324	Shared Neighborhood Hits	72
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

EHMT2_MOUSE
NC score	0.065731 (rank : 98)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	122	Target Neighborhood Hits	750	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

INVS_MOUSE
NC score	0.065225 (rank : 99)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	122	Target Neighborhood Hits	609	Shared Neighborhood Hits	73
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB15_HUMAN
NC score	0.065207 (rank : 100)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	122	Target Neighborhood Hits	305	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB1_HUMAN
NC score	0.064485 (rank : 101)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	122	Target Neighborhood Hits	470	Shared Neighborhood Hits	76
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

ASB1_HUMAN
NC score	0.064474 (rank : 102)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	122	Target Neighborhood Hits	291	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

MIB1_MOUSE
NC score	0.064472 (rank : 103)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	122	Target Neighborhood Hits	471	Shared Neighborhood Hits	76
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

INVS_HUMAN
NC score	0.063971 (rank : 104)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	122	Target Neighborhood Hits	455	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

FANK1_HUMAN
NC score	0.063539 (rank : 105)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	122	Target Neighborhood Hits	326	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ASB2_MOUSE
NC score	0.063515 (rank : 106)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	122	Target Neighborhood Hits	321	Shared Neighborhood Hits	69
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR26_HUMAN
NC score	0.062409 (rank : 107)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	122	Target Neighborhood Hits	1614	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MYPT2_HUMAN
NC score	0.062401 (rank : 108)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	122	Target Neighborhood Hits	707	Shared Neighborhood Hits	77
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANR19_HUMAN
NC score	0.062083 (rank : 109)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	122	Target Neighborhood Hits	276	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

PA2G6_MOUSE
NC score	0.061665 (rank : 110)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	72
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

POT22_HUMAN
NC score	0.060275 (rank : 111)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	122	Target Neighborhood Hits	266	Shared Neighborhood Hits	59
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

AN36A_HUMAN
NC score	0.059606 (rank : 112)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	122	Target Neighborhood Hits	271	Shared Neighborhood Hits	64
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR25_MOUSE
NC score	0.058089 (rank : 113)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	122	Target Neighborhood Hits	398	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASB14_MOUSE
NC score	0.057871 (rank : 114)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANFY1_HUMAN
NC score	0.057134 (rank : 115)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	122	Target Neighborhood Hits	480	Shared Neighborhood Hits	69
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BCL3_MOUSE
NC score	0.056877 (rank : 116)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	122	Target Neighborhood Hits	388	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANKR6_HUMAN
NC score	0.056876 (rank : 117)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	122	Target Neighborhood Hits	439	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

CT012_MOUSE
NC score	0.056828 (rank : 118)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	122	Target Neighborhood Hits	229	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

AN30A_HUMAN
NC score	0.056412 (rank : 119)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	122	Target Neighborhood Hits	1119	Shared Neighborhood Hits	81
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

FANK1_MOUSE
NC score	0.056128 (rank : 120)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	122	Target Neighborhood Hits	325	Shared Neighborhood Hits	66
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ASB15_MOUSE
NC score	0.056103 (rank : 121)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	122	Target Neighborhood Hits	292	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB7_HUMAN
NC score	0.056052 (rank : 122)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	122	Target Neighborhood Hits	296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
NC score	0.056023 (rank : 123)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	122	Target Neighborhood Hits	296	Shared Neighborhood Hits	64
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANRA2_MOUSE
NC score	0.055856 (rank : 124)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	122	Target Neighborhood Hits	287	Shared Neighborhood Hits	65
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANKR1_HUMAN
NC score	0.055668 (rank : 125)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	122	Target Neighborhood Hits	308	Shared Neighborhood Hits	63
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANRA2_HUMAN
NC score	0.055389 (rank : 126)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	122	Target Neighborhood Hits	288	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANR46_HUMAN
NC score	0.055313 (rank : 127)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	122	Target Neighborhood Hits	281	Shared Neighborhood Hits	66
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR38_HUMAN
NC score	0.055024 (rank : 128)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	122	Target Neighborhood Hits	443	Shared Neighborhood Hits	72
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR16_HUMAN
NC score	0.054984 (rank : 129)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	60
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

PSD10_HUMAN
NC score	0.054953 (rank : 130)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	122	Target Neighborhood Hits	301	Shared Neighborhood Hits	67
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR32_MOUSE
NC score	0.054900 (rank : 131)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	122	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

PA2G6_HUMAN
NC score	0.054664 (rank : 132)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

IKBA_HUMAN
NC score	0.054640 (rank : 133)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	122	Target Neighborhood Hits	280	Shared Neighborhood Hits	69
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

IKBE_MOUSE
NC score	0.054463 (rank : 134)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	122	Target Neighborhood Hits	308	Shared Neighborhood Hits	68
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

IKBA_MOUSE
NC score	0.054179 (rank : 135)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	122	Target Neighborhood Hits	283	Shared Neighborhood Hits	68
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ASB6_MOUSE
NC score	0.054162 (rank : 136)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	122	Target Neighborhood Hits	264	Shared Neighborhood Hits	66
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR18_HUMAN
NC score	0.054096 (rank : 137)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	122	Target Neighborhood Hits	1106	Shared Neighborhood Hits	80
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

ANR49_MOUSE
NC score	0.054050 (rank : 138)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	122	Target Neighborhood Hits	285	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB6_HUMAN
NC score	0.054019 (rank : 139)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	122	Target Neighborhood Hits	256	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANKR2_HUMAN
NC score	0.053290 (rank : 140)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	122	Target Neighborhood Hits	321	Shared Neighborhood Hits	66
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

IKBB_MOUSE
NC score	0.053026 (rank : 141)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	68
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANKR2_MOUSE
NC score	0.052779 (rank : 142)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	122	Target Neighborhood Hits	312	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR46_MOUSE
NC score	0.052746 (rank : 143)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	122	Target Neighborhood Hits	274	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB8_HUMAN
NC score	0.052660 (rank : 144)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	122	Target Neighborhood Hits	294	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

MIB2_HUMAN
NC score	0.052551 (rank : 145)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	122	Target Neighborhood Hits	438	Shared Neighborhood Hits	68
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

IKBB_HUMAN
NC score	0.052300 (rank : 146)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	66
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ANR33_MOUSE
NC score	0.052180 (rank : 147)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	122	Target Neighborhood Hits	225	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

PSD10_MOUSE
NC score	0.052007 (rank : 148)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ASB8_MOUSE
NC score	0.051691 (rank : 149)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	122	Target Neighborhood Hits	293	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR39_HUMAN
NC score	0.051604 (rank : 150)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	122	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

MTPN_MOUSE
NC score	0.051470 (rank : 151)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	122	Target Neighborhood Hits	269	Shared Neighborhood Hits	59
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

MIB2_MOUSE
NC score	0.051438 (rank : 152)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	122	Target Neighborhood Hits	409	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

MTPN_HUMAN
NC score	0.051415 (rank : 153)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	122	Target Neighborhood Hits	269	Shared Neighborhood Hits	59
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANR32_HUMAN
NC score	0.051341 (rank : 154)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	122	Target Neighborhood Hits	270	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

CDN2D_HUMAN
NC score	0.051202 (rank : 155)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	122	Target Neighborhood Hits	268	Shared Neighborhood Hits	63
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB16_MOUSE
NC score	0.050906 (rank : 156)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	122	Target Neighborhood Hits	306	Shared Neighborhood Hits	65
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANKS3_HUMAN
NC score	0.050870 (rank : 157)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	122	Target Neighborhood Hits	355	Shared Neighborhood Hits	65
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

MYPT1_MOUSE
NC score	0.050649 (rank : 158)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	122	Target Neighborhood Hits	539	Shared Neighborhood Hits	76
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

A20A2_HUMAN
NC score	0.050623 (rank : 159)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	122	Target Neighborhood Hits	716	Shared Neighborhood Hits	74
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANR33_HUMAN
NC score	0.050538 (rank : 160)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	122	Target Neighborhood Hits	215	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR39_MOUSE
NC score	0.050493 (rank : 161)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	122	Target Neighborhood Hits	284	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

CLPB_HUMAN
NC score	0.050491 (rank : 162)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	122	Target Neighborhood Hits	265	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ASB16_HUMAN
NC score	0.050173 (rank : 163)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	122	Target Neighborhood Hits	286	Shared Neighborhood Hits	62
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

IKBE_HUMAN
NC score	0.050149 (rank : 164)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	122	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ANR22_HUMAN
NC score	0.050091 (rank : 165)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	122	Target Neighborhood Hits	243	Shared Neighborhood Hits	58
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

UACA_HUMAN
NC score	0.045222 (rank : 166)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	122	Target Neighborhood Hits	1622	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

RIPK4_HUMAN
NC score	0.043289 (rank : 167)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	122	Target Neighborhood Hits	1094	Shared Neighborhood Hits	80
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

AN13B_HUMAN
NC score	0.043165 (rank : 168)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	122	Target Neighborhood Hits	265	Shared Neighborhood Hits	61
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
NC score	0.043161 (rank : 169)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	122	Target Neighborhood Hits	276	Shared Neighborhood Hits	61
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANKK1_HUMAN
NC score	0.041725 (rank : 170)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	122	Target Neighborhood Hits	1075	Shared Neighborhood Hits	77
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

UACA_MOUSE
NC score	0.038722 (rank : 171)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	122	Target Neighborhood Hits	1620	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

TFAM_HUMAN
NC score	0.038197 (rank : 172)	θ value	0.0961366 (rank : 50)
Query Neighborhood Hits	122	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

CT026_HUMAN
NC score	0.037585 (rank : 173)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	122	Target Neighborhood Hits	25	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NHU2, Q5TE18, Q8N5R9, Q96M59, Q9BQL2, Q9H127, Q9H128, Q9NQH4, Q9UFV8, Q9Y4V7	Gene names	C20orf26
Domain Architecture
Description	Uncharacterized protein C20orf26.

SC10A_HUMAN
NC score	0.033452 (rank : 174)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	122	Target Neighborhood Hits	116	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

GP156_MOUSE
NC score	0.031847 (rank : 175)	θ value	1.06291 (rank : 72)
Query Neighborhood Hits	122	Target Neighborhood Hits	95	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

SC10A_MOUSE
NC score	0.030703 (rank : 176)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	122	Target Neighborhood Hits	107	Shared Neighborhood Hits	22
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

TR143_MOUSE
NC score	0.028132 (rank : 177)	θ value	0.21417 (rank : 60)
Query Neighborhood Hits	122	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TQB9, Q2NL43	Gene names	Tas2r143, T2r36, Tas2r43
Domain Architecture
Description	Taste receptor type 2 member 143 (T2R143) (Taste receptor type 2 member 43) (T2R43) (mT2R36).

CAC1B_HUMAN
NC score	0.026801 (rank : 178)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	122	Target Neighborhood Hits	257	Shared Neighborhood Hits	16
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

IF2P_HUMAN
NC score	0.025373 (rank : 179)	θ value	0.365318 (rank : 63)
Query Neighborhood Hits	122	Target Neighborhood Hits	889	Shared Neighborhood Hits	24
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

GP156_HUMAN
NC score	0.024931 (rank : 180)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	122	Target Neighborhood Hits	84	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

TOM70_MOUSE
NC score	0.017111 (rank : 181)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	122	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_HUMAN
NC score	0.016601 (rank : 182)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	122	Target Neighborhood Hits	127	Shared Neighborhood Hits	3
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

F120A_HUMAN
NC score	0.015317 (rank : 183)	θ value	1.06291 (rank : 71)
Query Neighborhood Hits	122	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZB2, O60649, Q14688, Q4VXF4, Q4VXF5, Q4VXG2, Q96I21, Q9NZB1	Gene names	FAM120A, C9orf10, KIAA0183
Domain Architecture	No domain graphic available
Description	UPF0318 protein FAM120A.

NIN_MOUSE
NC score	0.015042 (rank : 184)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	122	Target Neighborhood Hits	1376	Shared Neighborhood Hits	31
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

RAI1_HUMAN
NC score	0.012712 (rank : 185)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	122	Target Neighborhood Hits	360	Shared Neighborhood Hits	6
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SYCP1_HUMAN
NC score	0.012385 (rank : 186)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	122	Target Neighborhood Hits	1313	Shared Neighborhood Hits	29
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EEA1_MOUSE
NC score	0.011250 (rank : 187)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	122	Target Neighborhood Hits	1637	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

AKAP9_HUMAN
NC score	0.010635 (rank : 188)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	122	Target Neighborhood Hits	1710	Shared Neighborhood Hits	36
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CN145_MOUSE
NC score	0.010256 (rank : 189)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	122	Target Neighborhood Hits	916	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

SFRS6_HUMAN
NC score	0.007494 (rank : 190)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	122	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	Q13247, Q13244, Q13245, Q96J06, Q9UJB8, Q9Y3N7	Gene names	SFRS6, SRP55
Domain Architecture
Description	Splicing factor, arginine/serine-rich 6 (Pre-mRNA-splicing factor SRP55).

MYH9_HUMAN
NC score	0.004196 (rank : 191)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	122	Target Neighborhood Hits	1762	Shared Neighborhood Hits	31
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
NC score	0.003900 (rank : 192)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	122	Target Neighborhood Hits	1829	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

PRP4B_MOUSE
NC score	0.003354 (rank : 193)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	122	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

E41L2_MOUSE
NC score	0.002321 (rank : 194)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	122	Target Neighborhood Hits	459	Shared Neighborhood Hits	13
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

PRP4B_HUMAN
NC score	0.001382 (rank : 195)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	122	Target Neighborhood Hits	1030	Shared Neighborhood Hits	15
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

CTRO_MOUSE
NC score	0.000458 (rank : 196)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	122	Target Neighborhood Hits	2344	Shared Neighborhood Hits	31
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ROCK2_HUMAN
NC score	0.000276 (rank : 197)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	122	Target Neighborhood Hits	2073	Shared Neighborhood Hits	30
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
NC score	-0.000283 (rank : 198)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	122	Target Neighborhood Hits	2072	Shared Neighborhood Hits	27
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).