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Network neighborhood for query Sequence : TRPC2_MOUSE

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TRPC2_MOUSE
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPC2_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_HUMAN
θ value	6.86991e-125 (rank : 2)	NC score	0.946199 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	9.92011e-124 (rank : 3)	NC score	0.948796 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_HUMAN
θ value	3.52827e-121 (rank : 4)	NC score	0.942432 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC6_MOUSE
θ value	5.63297e-119 (rank : 5)	NC score	0.946115 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	9.30652e-114 (rank : 6)	NC score	0.947118 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	4.61877e-113 (rank : 7)	NC score	0.947627 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC4_MOUSE
θ value	4.04623e-109 (rank : 8)	NC score	0.947942 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC4_HUMAN
θ value	1.53757e-108 (rank : 9)	NC score	0.948122 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC5_MOUSE
θ value	3.10529e-101 (rank : 10)	NC score	0.947849 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
θ value	1.18001e-100 (rank : 11)	NC score	0.947630 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	122	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC1_HUMAN
θ value	3.0147e-88 (rank : 12)	NC score	0.940615 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	3.0147e-88 (rank : 13)	NC score	0.941288 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPM8_MOUSE
θ value	8.38298e-14 (rank : 14)	NC score	0.530121 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
θ value	4.16044e-13 (rank : 15)	NC score	0.526969 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM7_HUMAN
θ value	6.64225e-11 (rank : 16)	NC score	0.441360 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM7_MOUSE
θ value	3.29651e-10 (rank : 17)	NC score	0.444039 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM6_MOUSE
θ value	2.36244e-08 (rank : 18)	NC score	0.435137 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_HUMAN
θ value	3.08544e-08 (rank : 19)	NC score	0.412858 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

XRCC1_HUMAN
θ value	6.87365e-08 (rank : 20)	NC score	0.134812 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TRPV6_HUMAN
θ value	4.45536e-07 (rank : 21)	NC score	0.234559 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV6_MOUSE
θ value	7.59969e-07 (rank : 22)	NC score	0.220633 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

XRCC1_MOUSE
θ value	1.29631e-06 (rank : 23)	NC score	0.122541 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TRPV5_MOUSE
θ value	1.69304e-06 (rank : 24)	NC score	0.237084 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPM3_HUMAN
θ value	8.40245e-06 (rank : 25)	NC score	0.363806 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV3_HUMAN
θ value	1.09739e-05 (rank : 26)	NC score	0.313938 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	198	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPM2_MOUSE
θ value	7.1131e-05 (rank : 27)	NC score	0.414491 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPV5_HUMAN
θ value	7.1131e-05 (rank : 28)	NC score	0.206211 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	261	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV3_MOUSE
θ value	0.00020696 (rank : 29)	NC score	0.293945 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_MOUSE
θ value	0.00035302 (rank : 30)	NC score	0.261063 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	189	Shared Neighborhood Hits	38
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPM2_HUMAN
θ value	0.000461057 (rank : 31)	NC score	0.438888 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPV1_HUMAN
θ value	0.000786445 (rank : 32)	NC score	0.261385 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	184	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

RN126_HUMAN
θ value	0.0252991 (rank : 33)	NC score	0.042255 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
θ value	0.0252991 (rank : 34)	NC score	0.041325 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

TATD2_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.054302 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

MDC1_HUMAN
θ value	0.125558 (rank : 36)	NC score	0.017093 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TRPV4_HUMAN
θ value	0.163984 (rank : 37)	NC score	0.227115 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	150	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ANR25_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.029729 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	398	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASAH3_MOUSE
θ value	0.279714 (rank : 39)	NC score	0.027967 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4X1	Gene names	Asah3, Acer1
Domain Architecture	No domain graphic available
Description	Alkaline ceramidase 1 (EC 3.5.1.23) (Alkaline CDase-1) (AlkCDase 1) (maCER1) (Acylsphingosine deacylase 3) (N-acylsphingosine amidohydrolase 3).

TRPV4_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.210318 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CNOT3_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.029904 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SC11A_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.021812 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	116	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

ANK3_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.045438 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	853	Shared Neighborhood Hits	34
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ZFP95_HUMAN
θ value	1.06291 (rank : 44)	NC score	-0.002212 (rank : 96)
Query Neighborhood Hits	84	Target Neighborhood Hits	775	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

K0562_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.020036 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

KSR1_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.000152 (rank : 94)
Query Neighborhood Hits	84	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

NPAS4_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.020929 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

SC11A_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.024979 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CNOT3_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.024140 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	504	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

NELF_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.018905 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NF2, Q8BPT0, Q8C9R5, Q9DBF4, Q9ERZ1	Gene names	Nelf, Jac
Domain Architecture	No domain graphic available
Description	Nasal embryonic luteinizing hormone-releasing hormone factor (Nasal embryonic LHRH factor) (Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein).

NPAS4_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.020175 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

ANK2_HUMAN
θ value	2.36792 (rank : 52)	NC score	0.036418 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	1615	Shared Neighborhood Hits	42
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ENAM_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.017083 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

CAN2_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.007308 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

PAX6_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.004222 (rank : 89)
Query Neighborhood Hits	84	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.004222 (rank : 90)
Query Neighborhood Hits	84	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

TARA_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.006780 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	1626	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

C2TA_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.010259 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	190	Shared Neighborhood Hits	7
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

GA2L2_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.009039 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

HRSL5_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.010830 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPX5, Q9CVQ2, Q9CVS0	Gene names	Hrasls5, Hrlp5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

MA1A1_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.007322 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P45700	Gene names	Man1a1, Man1a
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

REEP2_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.008298 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCD6	Gene names	Reep2
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 2.

SETX_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.009450 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

TRPA1_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.060441 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	339	Shared Neighborhood Hits	29
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

UBE3C_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.005751 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

CAN2_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.006606 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CYLD_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.010279 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

ALEX_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.009634 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	361	Shared Neighborhood Hits	7
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

CABP4_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.003272 (rank : 91)
Query Neighborhood Hits	84	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CN133_MOUSE
θ value	6.88961 (rank : 70)	NC score	0.009987 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ1, Q8BL55, Q8CIK4, Q91YI3	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf133 homolog.

FBX21_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.009569 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDH1, Q8BHA5, Q8CHC6	Gene names	Fbxo21, Fbx21, Kiaa0875
Domain Architecture	No domain graphic available
Description	F-box only protein 21.

LRC47_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.002373 (rank : 93)
Query Neighborhood Hits	84	Target Neighborhood Hits	299	Shared Neighborhood Hits	2
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

LSD1_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.005085 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	455	Shared Neighborhood Hits	3
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MDC1_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.013295 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	998	Shared Neighborhood Hits	18
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

RN5A_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.045907 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	899	Shared Neighborhood Hits	30
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ZN672_MOUSE
θ value	6.88961 (rank : 76)	NC score	-0.003277 (rank : 97)
Query Neighborhood Hits	84	Target Neighborhood Hits	738	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LH4, Q8BIR7	Gene names	Znf672, Zfp672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.

DGAT1_MOUSE
θ value	8.99809 (rank : 77)	NC score	0.006750 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2A7, Q9D7Q5	Gene names	Dgat1, Dgat
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase).

GON4L_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.005230 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	555	Shared Neighborhood Hits	6
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MFN2_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.005279 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

PSD10_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.014041 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	301	Shared Neighborhood Hits	17
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

RBBP8_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.008110 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	476	Shared Neighborhood Hits	4
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

RIMS1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.004426 (rank : 88)
Query Neighborhood Hits	84	Target Neighborhood Hits	437	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

ROBO3_HUMAN
θ value	8.99809 (rank : 83)	NC score	-0.001079 (rank : 95)
Query Neighborhood Hits	84	Target Neighborhood Hits	570	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

TTF2_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.002673 (rank : 92)
Query Neighborhood Hits	84	Target Neighborhood Hits	364	Shared Neighborhood Hits	5
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ACBD6_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.065848 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANK1_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.067419 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	416	Shared Neighborhood Hits	28
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.067379 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	430	Shared Neighborhood Hits	29
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANKS1_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.053716 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	438	Shared Neighborhood Hits	26
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANKY2_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.065821 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

PK2L1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.168088 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.099821 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.137708 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.120491 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.118911 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

TRPA1_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.050383 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.159166 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	130	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.166624 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

Hits sorted by NC score

TRPC2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_MOUSE
NC score	0.948796 (rank : 2)	θ value	9.92011e-124 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC4_HUMAN
NC score	0.948122 (rank : 3)	θ value	1.53757e-108 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.947942 (rank : 4)	θ value	4.04623e-109 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	141	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.947849 (rank : 5)	θ value	3.10529e-101 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.947630 (rank : 6)	θ value	1.18001e-100 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	122	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC7_MOUSE
NC score	0.947627 (rank : 7)	θ value	4.61877e-113 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.947118 (rank : 8)	θ value	9.30652e-114 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	123	Shared Neighborhood Hits	36
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC3_HUMAN
NC score	0.946199 (rank : 9)	θ value	6.86991e-125 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC6_MOUSE
NC score	0.946115 (rank : 10)	θ value	5.63297e-119 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC6_HUMAN
NC score	0.942432 (rank : 11)	θ value	3.52827e-121 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC1_MOUSE
NC score	0.941288 (rank : 12)	θ value	3.0147e-88 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	87	Shared Neighborhood Hits	37
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.940615 (rank : 13)	θ value	3.0147e-88 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	91	Shared Neighborhood Hits	37
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPM8_MOUSE
NC score	0.530121 (rank : 14)	θ value	8.38298e-14 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
NC score	0.526969 (rank : 15)	θ value	4.16044e-13 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	65	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM7_MOUSE
NC score	0.444039 (rank : 16)	θ value	3.29651e-10 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	113	Shared Neighborhood Hits	33
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
NC score	0.441360 (rank : 17)	θ value	6.64225e-11 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	104	Shared Neighborhood Hits	32
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM2_HUMAN
NC score	0.438888 (rank : 18)	θ value	0.000461057 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM6_MOUSE
NC score	0.435137 (rank : 19)	θ value	2.36244e-08 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM2_MOUSE
NC score	0.414491 (rank : 20)	θ value	7.1131e-05 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM6_HUMAN
NC score	0.412858 (rank : 21)	θ value	3.08544e-08 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM3_HUMAN
NC score	0.363806 (rank : 22)	θ value	8.40245e-06 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPV3_HUMAN
NC score	0.313938 (rank : 23)	θ value	1.09739e-05 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	198	Shared Neighborhood Hits	40
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.293945 (rank : 24)	θ value	0.00020696 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_HUMAN
NC score	0.261385 (rank : 25)	θ value	0.000786445 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	184	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
NC score	0.261063 (rank : 26)	θ value	0.00035302 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	189	Shared Neighborhood Hits	38
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV5_MOUSE
NC score	0.237084 (rank : 27)	θ value	1.69304e-06 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
NC score	0.234559 (rank : 28)	θ value	4.45536e-07 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	262	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV4_HUMAN
NC score	0.227115 (rank : 29)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	150	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV6_MOUSE
NC score	0.220633 (rank : 30)	θ value	7.59969e-07 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	284	Shared Neighborhood Hits	38
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV4_MOUSE
NC score	0.210318 (rank : 31)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_HUMAN
NC score	0.206211 (rank : 32)	θ value	7.1131e-05 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	261	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

PK2L1_HUMAN
NC score	0.168088 (rank : 33)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	84	Target Neighborhood Hits	132	Shared Neighborhood Hits	26
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TRPV2_MOUSE
NC score	0.166624 (rank : 34)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV2_HUMAN
NC score	0.159166 (rank : 35)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	84	Target Neighborhood Hits	130	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PK2L2_MOUSE
NC score	0.137708 (rank : 36)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

XRCC1_HUMAN
NC score	0.134812 (rank : 37)	θ value	6.87365e-08 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

XRCC1_MOUSE
NC score	0.122541 (rank : 38)	θ value	1.29631e-06 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q60596, Q3THC5, Q5U435, Q7TNQ5	Gene names	Xrcc1, Xrcc-1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

PKD2_HUMAN
NC score	0.120491 (rank : 39)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	84	Target Neighborhood Hits	105	Shared Neighborhood Hits	24
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKD2_MOUSE
NC score	0.118911 (rank : 40)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	84	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PK2L2_HUMAN
NC score	0.099821 (rank : 41)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	84	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

ANK1_HUMAN
NC score	0.067419 (rank : 42)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	416	Shared Neighborhood Hits	28
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANK1_MOUSE
NC score	0.067379 (rank : 43)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	430	Shared Neighborhood Hits	29
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ACBD6_MOUSE
NC score	0.065848 (rank : 44)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKY2_MOUSE
NC score	0.065821 (rank : 45)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	84	Target Neighborhood Hits	316	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

TRPA1_HUMAN
NC score	0.060441 (rank : 46)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	339	Shared Neighborhood Hits	29
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TATD2_HUMAN
NC score	0.054302 (rank : 47)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	66	Shared Neighborhood Hits	3
SwissProt Accessions	Q93075	Gene names	TATDN2, KIAA0218
Domain Architecture	No domain graphic available
Description	TatD DNase domain-containing deoxyribonuclease 2 (EC 3.1.21.-).

ANKS1_HUMAN
NC score	0.053716 (rank : 48)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	84	Target Neighborhood Hits	438	Shared Neighborhood Hits	26
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

TRPA1_MOUSE
NC score	0.050383 (rank : 49)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	84	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

RN5A_MOUSE
NC score	0.045907 (rank : 50)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	899	Shared Neighborhood Hits	30
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANK3_HUMAN
NC score	0.045438 (rank : 51)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	853	Shared Neighborhood Hits	34
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

RN126_HUMAN
NC score	0.042255 (rank : 52)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BV68, Q9NWX1	Gene names	RNF126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

RN126_MOUSE
NC score	0.041325 (rank : 53)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	Q91YL2	Gene names	Rnf126
Domain Architecture	No domain graphic available
Description	RING finger protein 126.

ANK2_HUMAN
NC score	0.036418 (rank : 54)	θ value	2.36792 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	1615	Shared Neighborhood Hits	42
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CNOT3_HUMAN
NC score	0.029904 (rank : 55)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	425	Shared Neighborhood Hits	9
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ANR25_MOUSE
NC score	0.029729 (rank : 56)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	398	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASAH3_MOUSE
NC score	0.027967 (rank : 57)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R4X1	Gene names	Asah3, Acer1
Domain Architecture	No domain graphic available
Description	Alkaline ceramidase 1 (EC 3.5.1.23) (Alkaline CDase-1) (AlkCDase 1) (maCER1) (Acylsphingosine deacylase 3) (N-acylsphingosine amidohydrolase 3).

SC11A_HUMAN
NC score	0.024979 (rank : 58)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	111	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CNOT3_MOUSE
NC score	0.024140 (rank : 59)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	504	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

SC11A_MOUSE
NC score	0.021812 (rank : 60)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	116	Shared Neighborhood Hits	13
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

NPAS4_MOUSE
NC score	0.020929 (rank : 61)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NPAS4_HUMAN
NC score	0.020175 (rank : 62)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

K0562_MOUSE
NC score	0.020036 (rank : 63)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q80V31, Q6ZQ95	Gene names	Kiaa0562
Domain Architecture	No domain graphic available
Description	Protein KIAA0562.

NELF_MOUSE
NC score	0.018905 (rank : 64)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NF2, Q8BPT0, Q8C9R5, Q9DBF4, Q9ERZ1	Gene names	Nelf, Jac
Domain Architecture	No domain graphic available
Description	Nasal embryonic luteinizing hormone-releasing hormone factor (Nasal embryonic LHRH factor) (Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein).

MDC1_HUMAN
NC score	0.017093 (rank : 65)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ENAM_HUMAN
NC score	0.017083 (rank : 66)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	227	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRM1, Q9H3D1	Gene names	ENAM
Domain Architecture
Description	Enamelin precursor.

PSD10_HUMAN
NC score	0.014041 (rank : 67)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	301	Shared Neighborhood Hits	17
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

MDC1_MOUSE
NC score	0.013295 (rank : 68)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	998	Shared Neighborhood Hits	18
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

HRSL5_MOUSE
NC score	0.010830 (rank : 69)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CPX5, Q9CVQ2, Q9CVS0	Gene names	Hrasls5, Hrlp5
Domain Architecture
Description	HRAS-like suppressor 5 (H-rev107-like protein 5).

CYLD_MOUSE
NC score	0.010279 (rank : 70)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

C2TA_HUMAN
NC score	0.010259 (rank : 71)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	190	Shared Neighborhood Hits	7
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CN133_MOUSE
NC score	0.009987 (rank : 72)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGQ1, Q8BL55, Q8CIK4, Q91YI3	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf133 homolog.

ALEX_HUMAN
NC score	0.009634 (rank : 73)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	361	Shared Neighborhood Hits	7
SwissProt Accessions	P84996	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

FBX21_MOUSE
NC score	0.009569 (rank : 74)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDH1, Q8BHA5, Q8CHC6	Gene names	Fbxo21, Fbx21, Kiaa0875
Domain Architecture	No domain graphic available
Description	F-box only protein 21.

SETX_HUMAN
NC score	0.009450 (rank : 75)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

GA2L2_MOUSE
NC score	0.009039 (rank : 76)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	395	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SSG4	Gene names	Gas2l2
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2).

REEP2_MOUSE
NC score	0.008298 (rank : 77)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCD6	Gene names	Reep2
Domain Architecture	No domain graphic available
Description	Receptor expression-enhancing protein 2.

RBBP8_HUMAN
NC score	0.008110 (rank : 78)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	476	Shared Neighborhood Hits	4
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

MA1A1_MOUSE
NC score	0.007322 (rank : 79)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	P45700	Gene names	Man1a1, Man1a
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

CAN2_MOUSE
NC score	0.007308 (rank : 80)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

TARA_HUMAN
NC score	0.006780 (rank : 81)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	1626	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

DGAT1_MOUSE
NC score	0.006750 (rank : 82)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2A7, Q9D7Q5	Gene names	Dgat1, Dgat
Domain Architecture
Description	Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Diglyceride acyltransferase).

CAN2_HUMAN
NC score	0.006606 (rank : 83)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

UBE3C_HUMAN
NC score	0.005751 (rank : 84)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q15386, Q8TC15, Q96CR4, Q9UDU3	Gene names	UBE3C, KIAA0010
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3C (EC 6.3.2.-).

MFN2_HUMAN
NC score	0.005279 (rank : 85)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	O95140, O95572, Q5JXC3, Q5JXC4, Q9H131, Q9NSX8	Gene names	MFN2, CPRP1, KIAA0214
Domain Architecture
Description	Transmembrane GTPase MFN2 (EC 3.6.5.-) (Mitofusin-2).

GON4L_HUMAN
NC score	0.005230 (rank : 86)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	555	Shared Neighborhood Hits	6
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

LSD1_HUMAN
NC score	0.005085 (rank : 87)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	455	Shared Neighborhood Hits	3
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

RIMS1_HUMAN
NC score	0.004426 (rank : 88)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	437	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

PAX6_HUMAN
NC score	0.004222 (rank : 89)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
NC score	0.004222 (rank : 90)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	383	Shared Neighborhood Hits	4
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

CABP4_HUMAN
NC score	0.003272 (rank : 91)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

TTF2_MOUSE
NC score	0.002673 (rank : 92)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	364	Shared Neighborhood Hits	5
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

LRC47_MOUSE
NC score	0.002373 (rank : 93)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	299	Shared Neighborhood Hits	2
SwissProt Accessions	Q505F5, Q3U380, Q6ZPW2, Q9CUZ0	Gene names	Lrrc47, Kiaa1185
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 47.

KSR1_MOUSE
NC score	0.000152 (rank : 94)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

ROBO3_HUMAN
NC score	-0.001079 (rank : 95)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	570	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

ZFP95_HUMAN
NC score	-0.002212 (rank : 96)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	775	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2L8	Gene names	ZFP95, KIAA1015
Domain Architecture
Description	Zinc finger protein 95 homolog (Zfp-95).

ZN672_MOUSE
NC score	-0.003277 (rank : 97)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	738	Shared Neighborhood Hits	3
SwissProt Accessions	Q99LH4, Q8BIR7	Gene names	Znf672, Zfp672
Domain Architecture	No domain graphic available
Description	Zinc finger protein 672.