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Network neighborhood for query Sequence : TRPM8_MOUSE

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TRPM8_MOUSE
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPM2_HUMAN
θ value	0 (rank : 1)	NC score	0.937109 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
θ value	0 (rank : 2)	NC score	0.934318 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM8_HUMAN
θ value	0 (rank : 3)	NC score	0.995674 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM6_HUMAN
θ value	1.70393e-99 (rank : 5)	NC score	0.839091 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM3_HUMAN
θ value	1.60224e-81 (rank : 6)	NC score	0.849207 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM7_MOUSE
θ value	2.94036e-59 (rank : 7)	NC score	0.833225 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM7_HUMAN
θ value	5.0155e-59 (rank : 8)	NC score	0.841301 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_MOUSE
θ value	2.18062e-54 (rank : 9)	NC score	0.843088 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPC4_HUMAN
θ value	2.87452e-22 (rank : 10)	NC score	0.592624 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	3.75424e-22 (rank : 11)	NC score	0.591414 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	141	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_HUMAN
θ value	1.2077e-20 (rank : 12)	NC score	0.578442 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	122	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	1.2077e-20 (rank : 13)	NC score	0.578549 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	124	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC2_MOUSE
θ value	8.38298e-14 (rank : 14)	NC score	0.530121 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_HUMAN
θ value	1.74796e-11 (rank : 15)	NC score	0.498568 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	2.98157e-11 (rank : 16)	NC score	0.503130 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	131	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC1_HUMAN
θ value	2.13673e-09 (rank : 17)	NC score	0.475194 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	2.13673e-09 (rank : 18)	NC score	0.475596 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	87	Shared Neighborhood Hits	33
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC6_MOUSE
θ value	4.76016e-09 (rank : 19)	NC score	0.465590 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_MOUSE
θ value	8.11959e-09 (rank : 20)	NC score	0.458337 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	114	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC6_HUMAN
θ value	1.38499e-08 (rank : 21)	NC score	0.462201 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_HUMAN
θ value	4.0297e-08 (rank : 22)	NC score	0.456181 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	123	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPV3_HUMAN
θ value	9.92553e-07 (rank : 23)	NC score	0.309003 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	3.77169e-06 (rank : 24)	NC score	0.301726 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	3.19293e-05 (rank : 25)	NC score	0.243312 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	150	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	0.00020696 (rank : 26)	NC score	0.223488 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV1_HUMAN
θ value	0.000461057 (rank : 27)	NC score	0.245098 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	0.00509761 (rank : 28)	NC score	0.240020 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

CAC1B_MOUSE
θ value	0.0113563 (rank : 29)	NC score	0.069565 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	351	Shared Neighborhood Hits	17
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

TRPV2_MOUSE
θ value	0.0113563 (rank : 30)	NC score	0.185686 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CAC1B_HUMAN
θ value	0.0148317 (rank : 31)	NC score	0.070867 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	257	Shared Neighborhood Hits	20
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1E_HUMAN
θ value	0.0330416 (rank : 32)	NC score	0.062467 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	148	Shared Neighborhood Hits	16
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

TRPV2_HUMAN
θ value	0.0431538 (rank : 33)	NC score	0.169202 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CAC1E_MOUSE
θ value	0.0736092 (rank : 34)	NC score	0.061021 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

EI24_HUMAN
θ value	0.0961366 (rank : 35)	NC score	0.084591 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

EI24_MOUSE
θ value	0.0961366 (rank : 36)	NC score	0.084896 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q61070	Gene names	Ei24, Pig8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

TRPV6_MOUSE
θ value	0.0961366 (rank : 37)	NC score	0.178952 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	284	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV6_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.194192 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	262	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

PK2L1_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.124972 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

CAC1A_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.054732 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SC10A_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.048395 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1A_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.051813 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	387	Shared Neighborhood Hits	15
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN7A_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.041875 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	135	Shared Neighborhood Hits	20
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SC10A_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.044653 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	116	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC11A_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.044869 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

DYH11_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.010034 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	234	Shared Neighborhood Hits	6
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

NPAL2_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.019554 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H841	Gene names	NPAL2
Domain Architecture	No domain graphic available
Description	NIPA-like protein 2.

MYH4_MOUSE
θ value	5.27518 (rank : 48)	NC score	-0.000228 (rank : 67)
Query Neighborhood Hits	58	Target Neighborhood Hits	1476	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

TRPA1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.035584 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	339	Shared Neighborhood Hits	27
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ATP5H_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.026933 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O75947, Q9H3J4	Gene names	ATP5H
Domain Architecture
Description	ATP synthase D chain, mitochondrial (EC 3.6.3.14).

GOGA4_HUMAN
θ value	6.88961 (rank : 51)	NC score	-0.002030 (rank : 68)
Query Neighborhood Hits	58	Target Neighborhood Hits	2034	Shared Neighborhood Hits	5
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MPZL1_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.014685 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O95297, Q5R332, Q8IX11, Q9BWZ3, Q9NYK4, Q9UL20	Gene names	MPZL1, PZR
Domain Architecture	No domain graphic available
Description	Myelin protein zero-like protein 1 precursor (Protein zero-related).

MRGRG_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.005620 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SM5	Gene names	MRGPRG, GPR169, MRGG
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member G (G-protein coupled receptor 169).

CENPF_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.002341 (rank : 66)
Query Neighborhood Hits	58	Target Neighborhood Hits	1932	Shared Neighborhood Hits	11
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

FAIM2_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.009899 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWQ8, Q9UJY9, Q9Y2F7	Gene names	FAIM2, KIAA0950, LFG, TMBIM2
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2).

FAIM2_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.009995 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K097, Q3TY22, Q8K1F6, Q9D6K4	Gene names	Faim2, Kiaa0950, Lfg
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein).

MFA3L_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.004208 (rank : 65)
Query Neighborhood Hits	58	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

PKD2_HUMAN
θ value	8.99809 (rank : 58)	NC score	0.078415 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

EF2K_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.127071 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.131935 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

NUD9P_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.157758 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

NUDT9_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.208432 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.209862 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

PK2L2_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.079663 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.089101 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.070124 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	99	Shared Neighborhood Hits	27
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

TRPV5_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.166587 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	261	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV5_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.164707 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

Hits sorted by NC score

TRPM8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	58	Target Neighborhood Hits	58	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM8_HUMAN
NC score	0.995674 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	58	Target Neighborhood Hits	65	Shared Neighborhood Hits	53
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM2_HUMAN
NC score	0.937109 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	58	Target Neighborhood Hits	64	Shared Neighborhood Hits	31
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
NC score	0.934318 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	58	Target Neighborhood Hits	61	Shared Neighborhood Hits	33
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM3_HUMAN
NC score	0.849207 (rank : 5)	θ value	1.60224e-81 (rank : 6)
Query Neighborhood Hits	58	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM6_MOUSE
NC score	0.843088 (rank : 6)	θ value	2.18062e-54 (rank : 9)
Query Neighborhood Hits	58	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM7_HUMAN
NC score	0.841301 (rank : 7)	θ value	5.0155e-59 (rank : 8)
Query Neighborhood Hits	58	Target Neighborhood Hits	104	Shared Neighborhood Hits	34
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_HUMAN
NC score	0.839091 (rank : 8)	θ value	1.70393e-99 (rank : 5)
Query Neighborhood Hits	58	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM7_MOUSE
NC score	0.833225 (rank : 9)	θ value	2.94036e-59 (rank : 7)
Query Neighborhood Hits	58	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPC4_HUMAN
NC score	0.592624 (rank : 10)	θ value	2.87452e-22 (rank : 10)
Query Neighborhood Hits	58	Target Neighborhood Hits	140	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.591414 (rank : 11)	θ value	3.75424e-22 (rank : 11)
Query Neighborhood Hits	58	Target Neighborhood Hits	141	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.578549 (rank : 12)	θ value	1.2077e-20 (rank : 13)
Query Neighborhood Hits	58	Target Neighborhood Hits	124	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.578442 (rank : 13)	θ value	1.2077e-20 (rank : 12)
Query Neighborhood Hits	58	Target Neighborhood Hits	122	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC2_MOUSE
NC score	0.530121 (rank : 14)	θ value	8.38298e-14 (rank : 14)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_MOUSE
NC score	0.503130 (rank : 15)	θ value	2.98157e-11 (rank : 16)
Query Neighborhood Hits	58	Target Neighborhood Hits	131	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC3_HUMAN
NC score	0.498568 (rank : 16)	θ value	1.74796e-11 (rank : 15)
Query Neighborhood Hits	58	Target Neighborhood Hits	137	Shared Neighborhood Hits	33
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC1_MOUSE
NC score	0.475596 (rank : 17)	θ value	2.13673e-09 (rank : 18)
Query Neighborhood Hits	58	Target Neighborhood Hits	87	Shared Neighborhood Hits	33
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.475194 (rank : 18)	θ value	2.13673e-09 (rank : 17)
Query Neighborhood Hits	58	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC6_MOUSE
NC score	0.465590 (rank : 19)	θ value	4.76016e-09 (rank : 19)
Query Neighborhood Hits	58	Target Neighborhood Hits	171	Shared Neighborhood Hits	33
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC6_HUMAN
NC score	0.462201 (rank : 20)	θ value	1.38499e-08 (rank : 21)
Query Neighborhood Hits	58	Target Neighborhood Hits	171	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_MOUSE
NC score	0.458337 (rank : 21)	θ value	8.11959e-09 (rank : 20)
Query Neighborhood Hits	58	Target Neighborhood Hits	114	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.456181 (rank : 22)	θ value	4.0297e-08 (rank : 22)
Query Neighborhood Hits	58	Target Neighborhood Hits	123	Shared Neighborhood Hits	35
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPV3_HUMAN
NC score	0.309003 (rank : 23)	θ value	9.92553e-07 (rank : 23)
Query Neighborhood Hits	58	Target Neighborhood Hits	198	Shared Neighborhood Hits	39
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.301726 (rank : 24)	θ value	3.77169e-06 (rank : 24)
Query Neighborhood Hits	58	Target Neighborhood Hits	188	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV1_HUMAN
NC score	0.245098 (rank : 25)	θ value	0.000461057 (rank : 27)
Query Neighborhood Hits	58	Target Neighborhood Hits	184	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV4_HUMAN
NC score	0.243312 (rank : 26)	θ value	3.19293e-05 (rank : 25)
Query Neighborhood Hits	58	Target Neighborhood Hits	150	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV1_MOUSE
NC score	0.240020 (rank : 27)	θ value	0.00509761 (rank : 28)
Query Neighborhood Hits	58	Target Neighborhood Hits	189	Shared Neighborhood Hits	36
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV4_MOUSE
NC score	0.223488 (rank : 28)	θ value	0.00020696 (rank : 26)
Query Neighborhood Hits	58	Target Neighborhood Hits	117	Shared Neighborhood Hits	37
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

NUDT9_MOUSE
NC score	0.209862 (rank : 29)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	58	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_HUMAN
NC score	0.208432 (rank : 30)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	58	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

TRPV6_HUMAN
NC score	0.194192 (rank : 31)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	58	Target Neighborhood Hits	262	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV2_MOUSE
NC score	0.185686 (rank : 32)	θ value	0.0113563 (rank : 30)
Query Neighborhood Hits	58	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV6_MOUSE
NC score	0.178952 (rank : 33)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	58	Target Neighborhood Hits	284	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV2_HUMAN
NC score	0.169202 (rank : 34)	θ value	0.0431538 (rank : 33)
Query Neighborhood Hits	58	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV5_HUMAN
NC score	0.166587 (rank : 35)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	58	Target Neighborhood Hits	261	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV5_MOUSE
NC score	0.164707 (rank : 36)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	58	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

NUD9P_HUMAN
NC score	0.157758 (rank : 37)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	58	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

EF2K_MOUSE
NC score	0.131935 (rank : 38)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	58	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_HUMAN
NC score	0.127071 (rank : 39)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	58	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

PK2L1_HUMAN
NC score	0.124972 (rank : 40)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	58	Target Neighborhood Hits	132	Shared Neighborhood Hits	34
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.089101 (rank : 41)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	58	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

EI24_MOUSE
NC score	0.084896 (rank : 42)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	58	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q61070	Gene names	Ei24, Pig8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

EI24_HUMAN
NC score	0.084591 (rank : 43)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	58	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	O14681	Gene names	EI24, PIG8
Domain Architecture
Description	Etoposide-induced protein 2.4 (p53-induced protein 8).

PK2L2_HUMAN
NC score	0.079663 (rank : 44)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	58	Target Neighborhood Hits	90	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
NC score	0.078415 (rank : 45)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	58	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

CAC1B_HUMAN
NC score	0.070867 (rank : 46)	θ value	0.0148317 (rank : 31)
Query Neighborhood Hits	58	Target Neighborhood Hits	257	Shared Neighborhood Hits	20
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PKD2_MOUSE
NC score	0.070124 (rank : 47)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	58	Target Neighborhood Hits	99	Shared Neighborhood Hits	27
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

CAC1B_MOUSE
NC score	0.069565 (rank : 48)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	58	Target Neighborhood Hits	351	Shared Neighborhood Hits	17
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1E_HUMAN
NC score	0.062467 (rank : 49)	θ value	0.0330416 (rank : 32)
Query Neighborhood Hits	58	Target Neighborhood Hits	148	Shared Neighborhood Hits	16
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
NC score	0.061021 (rank : 50)	θ value	0.0736092 (rank : 34)
Query Neighborhood Hits	58	Target Neighborhood Hits	167	Shared Neighborhood Hits	16
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.054732 (rank : 51)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	58	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_HUMAN
NC score	0.051813 (rank : 52)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	58	Target Neighborhood Hits	387	Shared Neighborhood Hits	15
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SC10A_MOUSE
NC score	0.048395 (rank : 53)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	58	Target Neighborhood Hits	107	Shared Neighborhood Hits	25
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC11A_MOUSE
NC score	0.044869 (rank : 54)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	58	Target Neighborhood Hits	116	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC10A_HUMAN
NC score	0.044653 (rank : 55)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	58	Target Neighborhood Hits	116	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN7A_HUMAN
NC score	0.041875 (rank : 56)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	58	Target Neighborhood Hits	135	Shared Neighborhood Hits	20
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

TRPA1_HUMAN
NC score	0.035584 (rank : 57)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	58	Target Neighborhood Hits	339	Shared Neighborhood Hits	27
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ATP5H_HUMAN
NC score	0.026933 (rank : 58)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	58	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	O75947, Q9H3J4	Gene names	ATP5H
Domain Architecture
Description	ATP synthase D chain, mitochondrial (EC 3.6.3.14).

NPAL2_HUMAN
NC score	0.019554 (rank : 59)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	58	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H841	Gene names	NPAL2
Domain Architecture	No domain graphic available
Description	NIPA-like protein 2.

MPZL1_HUMAN
NC score	0.014685 (rank : 60)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	58	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	O95297, Q5R332, Q8IX11, Q9BWZ3, Q9NYK4, Q9UL20	Gene names	MPZL1, PZR
Domain Architecture	No domain graphic available
Description	Myelin protein zero-like protein 1 precursor (Protein zero-related).

DYH11_HUMAN
NC score	0.010034 (rank : 61)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	58	Target Neighborhood Hits	234	Shared Neighborhood Hits	6
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

FAIM2_MOUSE
NC score	0.009995 (rank : 62)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	58	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K097, Q3TY22, Q8K1F6, Q9D6K4	Gene names	Faim2, Kiaa0950, Lfg
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein).

FAIM2_HUMAN
NC score	0.009899 (rank : 63)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	58	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BWQ8, Q9UJY9, Q9Y2F7	Gene names	FAIM2, KIAA0950, LFG, TMBIM2
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2).

MRGRG_HUMAN
NC score	0.005620 (rank : 64)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	58	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SM5	Gene names	MRGPRG, GPR169, MRGG
Domain Architecture	No domain graphic available
Description	Mas-related G-protein coupled receptor member G (G-protein coupled receptor 169).

MFA3L_MOUSE
NC score	0.004208 (rank : 65)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	58	Target Neighborhood Hits	214	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

CENPF_HUMAN
NC score	0.002341 (rank : 66)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	58	Target Neighborhood Hits	1932	Shared Neighborhood Hits	11
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MYH4_MOUSE
NC score	-0.000228 (rank : 67)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	58	Target Neighborhood Hits	1476	Shared Neighborhood Hits	6
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

GOGA4_HUMAN
NC score	-0.002030 (rank : 68)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	58	Target Neighborhood Hits	2034	Shared Neighborhood Hits	5
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).