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Network neighborhood for query Sequence : SCN7A_HUMAN

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SCN7A_HUMAN
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SC10A_HUMAN
θ value	0 (rank : 1)	NC score	0.981513 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC10A_MOUSE
θ value	0 (rank : 2)	NC score	0.980622 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC11A_HUMAN
θ value	0 (rank : 3)	NC score	0.983137 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	111	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	0 (rank : 4)	NC score	0.984827 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN1A_HUMAN
θ value	0 (rank : 5)	NC score	0.985313 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	56
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN2A_HUMAN
θ value	0 (rank : 6)	NC score	0.985672 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	56
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	0 (rank : 7)	NC score	0.986449 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN4A_HUMAN
θ value	0 (rank : 8)	NC score	0.989721 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
θ value	0 (rank : 9)	NC score	0.978532 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN7A_HUMAN
θ value	0 (rank : 10)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN8A_HUMAN
θ value	0 (rank : 11)	NC score	0.985606 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	0 (rank : 12)	NC score	0.985297 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
θ value	0 (rank : 13)	NC score	0.985220 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1C_MOUSE
θ value	5.67233e-95 (rank : 14)	NC score	0.851684 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	50
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1C_HUMAN
θ value	1.88829e-90 (rank : 15)	NC score	0.848490 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	158	Shared Neighborhood Hits	52
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1H_HUMAN
θ value	1.31987e-59 (rank : 16)	NC score	0.869295 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
θ value	1.7238e-59 (rank : 17)	NC score	0.876186 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	3.84025e-59 (rank : 18)	NC score	0.895687 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	138	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1E_MOUSE
θ value	8.55514e-59 (rank : 19)	NC score	0.862984 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	167	Shared Neighborhood Hits	50
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
θ value	1.45929e-58 (rank : 20)	NC score	0.862604 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_HUMAN
θ value	2.48917e-58 (rank : 21)	NC score	0.851338 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	2.48917e-58 (rank : 22)	NC score	0.859059 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	267	Shared Neighborhood Hits	61
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1F_MOUSE
θ value	3.59435e-57 (rank : 23)	NC score	0.850362 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	142	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1G_HUMAN
θ value	8.00737e-57 (rank : 24)	NC score	0.852488 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	587	Shared Neighborhood Hits	55
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1D_HUMAN
θ value	1.36585e-56 (rank : 25)	NC score	0.855685 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	56
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1F_HUMAN
θ value	1.78386e-56 (rank : 26)	NC score	0.849894 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_MOUSE
θ value	8.85319e-56 (rank : 27)	NC score	0.850112 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	351	Shared Neighborhood Hits	59
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1S_MOUSE
θ value	3.36421e-55 (rank : 28)	NC score	0.856526 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	54
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_HUMAN
θ value	1.66964e-54 (rank : 29)	NC score	0.853346 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	257	Shared Neighborhood Hits	56
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1S_HUMAN
θ value	2.18062e-54 (rank : 30)	NC score	0.855059 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	92	Shared Neighborhood Hits	53
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

KCNF1_HUMAN
θ value	0.0113563 (rank : 31)	NC score	0.217548 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNC4_HUMAN
θ value	0.0252991 (rank : 32)	NC score	0.114002 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNH2_HUMAN
θ value	0.0252991 (rank : 33)	NC score	0.018011 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	0.0252991 (rank : 34)	NC score	0.019201 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNA1_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.079537 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	45
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	0.0431538 (rank : 36)	NC score	0.080894 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	46
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNB2_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.197786 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

TRPV3_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.086090 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNC4_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.106469 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCND3_HUMAN
θ value	0.163984 (rank : 40)	NC score	0.162978 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.163118 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

PK2L1_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.267650 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCNA3_MOUSE
θ value	0.21417 (rank : 43)	NC score	0.069688 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

MEPE_HUMAN
θ value	0.21417 (rank : 44)	NC score	0.039495 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

KCNA5_MOUSE
θ value	0.365318 (rank : 45)	NC score	0.071493 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA3_HUMAN
θ value	0.47712 (rank : 46)	NC score	0.070266 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

PKD2_MOUSE
θ value	0.47712 (rank : 47)	NC score	0.248608 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	40
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

SEGN_HUMAN
θ value	0.47712 (rank : 48)	NC score	0.026503 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

KCND2_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.155114 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.155276 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

DZIP1_MOUSE
θ value	0.813845 (rank : 51)	NC score	0.013397 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	530	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

KCNQ4_HUMAN
θ value	0.813845 (rank : 52)	NC score	0.075006 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	45
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

RIF1_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.012981 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ZN318_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.019689 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	497	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

KCNA4_MOUSE
θ value	1.06291 (rank : 55)	NC score	0.056192 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	34
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNS2_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.189779 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

NPM2_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.018418 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SE8	Gene names	NPM2
Domain Architecture
Description	Nucleoplasmin-2.

TAXB1_HUMAN
θ value	1.06291 (rank : 58)	NC score	0.009494 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	829	Shared Neighborhood Hits	32
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TMF1_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.008353 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	987	Shared Neighborhood Hits	32
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

KCNA2_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.077179 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.078011 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

MKL1_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.012028 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	667	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MYH13_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.007861 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	1504	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PKD2_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.245715 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	43
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

TRPM2_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.016592 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

CP135_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.007413 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	1290	Shared Neighborhood Hits	32
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DDX23_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.003061 (rank : 147)
Query Neighborhood Hits	135	Target Neighborhood Hits	486	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

DRD1_MOUSE
θ value	1.81305 (rank : 68)	NC score	-0.000808 (rank : 156)
Query Neighborhood Hits	135	Target Neighborhood Hits	733	Shared Neighborhood Hits	3
SwissProt Accessions	Q61616, Q8C8P8	Gene names	Drd1, Drd1a, Gpcr15
Domain Architecture
Description	D(1A) dopamine receptor.

I17RA_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.010994 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

KCNA4_HUMAN
θ value	1.81305 (rank : 70)	NC score	0.055659 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA5_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.065813 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	124	Shared Neighborhood Hits	38
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA6_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.071763 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	42
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	1.81305 (rank : 73)	NC score	0.074927 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC1_HUMAN
θ value	1.81305 (rank : 74)	NC score	0.128919 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	58
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

PK2L2_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.286844 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPA1_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.005546 (rank : 138)
Query Neighborhood Hits	135	Target Neighborhood Hits	339	Shared Neighborhood Hits	11
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

TRPM8_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.041875 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

CALB2_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.026840 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
θ value	2.36792 (rank : 79)	NC score	0.027071 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

KCNC1_MOUSE
θ value	2.36792 (rank : 80)	NC score	0.126614 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	58
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNS2_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.184566 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

MAP1B_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.010640 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	977	Shared Neighborhood Hits	32
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYH6_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.007047 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	1426	Shared Neighborhood Hits	35
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	2.36792 (rank : 84)	NC score	0.007043 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	1501	Shared Neighborhood Hits	34
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.006763 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	1559	Shared Neighborhood Hits	32
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

TPR_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.008205 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	1921	Shared Neighborhood Hits	46
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ZC11A_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.012284 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

DRD1_HUMAN
θ value	3.0926 (rank : 88)	NC score	-0.001323 (rank : 157)
Query Neighborhood Hits	135	Target Neighborhood Hits	750	Shared Neighborhood Hits	3
SwissProt Accessions	P21728, Q4QRJ0	Gene names	DRD1
Domain Architecture
Description	D(1A) dopamine receptor.

KIF3A_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.002446 (rank : 150)
Query Neighborhood Hits	135	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

NCKX1_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.006104 (rank : 136)
Query Neighborhood Hits	135	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

RXINP_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.010458 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

CP135_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.006995 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	1278	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CROCC_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.007946 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	1460	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CT2NL_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.011657 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	1059	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

ERC2_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.006711 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	1156	Shared Neighborhood Hits	31
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.006729 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	1166	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

GPR64_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.002406 (rank : 152)
Query Neighborhood Hits	135	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

OAT6_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.004112 (rank : 144)
Query Neighborhood Hits	135	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UJ1	Gene names	Slc22a20, Gm963, Oat6
Domain Architecture	No domain graphic available
Description	Solute carrier family 22 member 20 (Organic anion transporter 6).

PIGW_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.009703 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7B1, Q8N9G3	Gene names	PIGW
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-glycan biosynthesis class W protein (EC 2.3.-.-) (PIG-W).

PLEC1_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.003399 (rank : 146)
Query Neighborhood Hits	135	Target Neighborhood Hits	1326	Shared Neighborhood Hits	30
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SMC1A_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.006939 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	1346	Shared Neighborhood Hits	33
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.006657 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	1384	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TRPV1_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.021245 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

CALM_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.002530 (rank : 148)
Query Neighborhood Hits	135	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	5.27518 (rank : 105)	NC score	0.002530 (rank : 149)
Query Neighborhood Hits	135	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CKAP4_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.007957 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	596	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

ITPR1_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.009390 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.009375 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

KCMA1_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.031710 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	96	Shared Neighborhood Hits	37
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.031766 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNS1_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.106632 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	55
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

MYH4_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.007869 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	1377	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH9_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.005688 (rank : 137)
Query Neighborhood Hits	135	Target Neighborhood Hits	1762	Shared Neighborhood Hits	39
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SEGN_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.016543 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

SMC4_MOUSE
θ value	5.27518 (rank : 115)	NC score	0.007608 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	830	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

DSPP_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.002415 (rank : 151)
Query Neighborhood Hits	135	Target Neighborhood Hits	645	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

KCNC3_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.104609 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	256	Shared Neighborhood Hits	57
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MAP1B_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.007780 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	903	Shared Neighborhood Hits	24
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NKTR_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.004460 (rank : 142)
Query Neighborhood Hits	135	Target Neighborhood Hits	658	Shared Neighborhood Hits	17
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

RB6I2_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.007743 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	1584	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

TRPM2_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.019774 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM8_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.035930 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

CENPF_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.003758 (rank : 145)
Query Neighborhood Hits	135	Target Neighborhood Hits	1932	Shared Neighborhood Hits	38
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CF152_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.006983 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	704	Shared Neighborhood Hits	34
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

HUWE1_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.002016 (rank : 154)
Query Neighborhood Hits	135	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

KCNB1_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.176887 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	169	Shared Neighborhood Hits	62
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.177025 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	63
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNC3_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.102305 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	173	Shared Neighborhood Hits	56
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MOR2A_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.002304 (rank : 153)
Query Neighborhood Hits	135	Target Neighborhood Hits	220	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

MYH10_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.005413 (rank : 139)
Query Neighborhood Hits	135	Target Neighborhood Hits	1620	Shared Neighborhood Hits	36
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.005279 (rank : 140)
Query Neighborhood Hits	135	Target Neighborhood Hits	1612	Shared Neighborhood Hits	35
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.005206 (rank : 141)
Query Neighborhood Hits	135	Target Neighborhood Hits	1829	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TMCC3_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.006352 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

WWP1_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.004304 (rank : 143)
Query Neighborhood Hits	135	Target Neighborhood Hits	262	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

WWP1_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.001973 (rank : 155)
Query Neighborhood Hits	135	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

CABP5_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.052512 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

KCND1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.134626 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.136555 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNG1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.053167 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG3_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.078435 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.078657 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.055557 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.064037 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	175	Shared Neighborhood Hits	43
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.051970 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNS1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.123835 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	61
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS3_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.156037 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNV2_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.197135 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	137	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

PK2L2_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.250235 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKDRE_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.097757 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	64	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.070325 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TPTE2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.129866 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

TPTE_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.086284 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TRPC1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.057140 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.057228 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPV3_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.056818 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.051454 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.052805 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

SCN7A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 10)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	135
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN4A_HUMAN
NC score	0.989721 (rank : 2)	θ value	0 (rank : 8)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	66
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN3A_HUMAN
NC score	0.986449 (rank : 3)	θ value	0 (rank : 7)
Query Neighborhood Hits	135	Target Neighborhood Hits	115	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN2A_HUMAN
NC score	0.985672 (rank : 4)	θ value	0 (rank : 6)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	56
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN8A_HUMAN
NC score	0.985606 (rank : 5)	θ value	0 (rank : 11)
Query Neighborhood Hits	135	Target Neighborhood Hits	135	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN1A_HUMAN
NC score	0.985313 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	56
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN8A_MOUSE
NC score	0.985297 (rank : 7)	θ value	0 (rank : 12)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	57
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
NC score	0.985220 (rank : 8)	θ value	0 (rank : 13)
Query Neighborhood Hits	135	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SC11A_MOUSE
NC score	0.984827 (rank : 9)	θ value	0 (rank : 4)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.983137 (rank : 10)	θ value	0 (rank : 3)
Query Neighborhood Hits	135	Target Neighborhood Hits	111	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC10A_HUMAN
NC score	0.981513 (rank : 11)	θ value	0 (rank : 1)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SC10A_MOUSE
NC score	0.980622 (rank : 12)	θ value	0 (rank : 2)
Query Neighborhood Hits	135	Target Neighborhood Hits	107	Shared Neighborhood Hits	61
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN5A_HUMAN
NC score	0.978532 (rank : 13)	θ value	0 (rank : 9)
Query Neighborhood Hits	135	Target Neighborhood Hits	145	Shared Neighborhood Hits	54
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1I_HUMAN
NC score	0.895687 (rank : 14)	θ value	3.84025e-59 (rank : 18)
Query Neighborhood Hits	135	Target Neighborhood Hits	138	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.876186 (rank : 15)	θ value	1.7238e-59 (rank : 17)
Query Neighborhood Hits	135	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.869295 (rank : 16)	θ value	1.31987e-59 (rank : 16)
Query Neighborhood Hits	135	Target Neighborhood Hits	307	Shared Neighborhood Hits	60
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1E_MOUSE
NC score	0.862984 (rank : 17)	θ value	8.55514e-59 (rank : 19)
Query Neighborhood Hits	135	Target Neighborhood Hits	167	Shared Neighborhood Hits	50
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.862604 (rank : 18)	θ value	1.45929e-58 (rank : 20)
Query Neighborhood Hits	135	Target Neighborhood Hits	148	Shared Neighborhood Hits	51
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1A_MOUSE
NC score	0.859059 (rank : 19)	θ value	2.48917e-58 (rank : 22)
Query Neighborhood Hits	135	Target Neighborhood Hits	267	Shared Neighborhood Hits	61
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1S_MOUSE
NC score	0.856526 (rank : 20)	θ value	3.36421e-55 (rank : 28)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	54
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1D_HUMAN
NC score	0.855685 (rank : 21)	θ value	1.36585e-56 (rank : 25)
Query Neighborhood Hits	135	Target Neighborhood Hits	118	Shared Neighborhood Hits	56
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_HUMAN
NC score	0.855059 (rank : 22)	θ value	2.18062e-54 (rank : 30)
Query Neighborhood Hits	135	Target Neighborhood Hits	92	Shared Neighborhood Hits	53
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_HUMAN
NC score	0.853346 (rank : 23)	θ value	1.66964e-54 (rank : 29)
Query Neighborhood Hits	135	Target Neighborhood Hits	257	Shared Neighborhood Hits	56
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1G_HUMAN
NC score	0.852488 (rank : 24)	θ value	8.00737e-57 (rank : 24)
Query Neighborhood Hits	135	Target Neighborhood Hits	587	Shared Neighborhood Hits	55
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1C_MOUSE
NC score	0.851684 (rank : 25)	θ value	5.67233e-95 (rank : 14)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	50
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1A_HUMAN
NC score	0.851338 (rank : 26)	θ value	2.48917e-58 (rank : 21)
Query Neighborhood Hits	135	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1F_MOUSE
NC score	0.850362 (rank : 27)	θ value	3.59435e-57 (rank : 23)
Query Neighborhood Hits	135	Target Neighborhood Hits	142	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_MOUSE
NC score	0.850112 (rank : 28)	θ value	8.85319e-56 (rank : 27)
Query Neighborhood Hits	135	Target Neighborhood Hits	351	Shared Neighborhood Hits	59
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_HUMAN
NC score	0.849894 (rank : 29)	θ value	1.78386e-56 (rank : 26)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1C_HUMAN
NC score	0.848490 (rank : 30)	θ value	1.88829e-90 (rank : 15)
Query Neighborhood Hits	135	Target Neighborhood Hits	158	Shared Neighborhood Hits	52
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.286844 (rank : 31)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	135	Target Neighborhood Hits	90	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.267650 (rank : 32)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	135	Target Neighborhood Hits	132	Shared Neighborhood Hits	46
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.250235 (rank : 33)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	135	Target Neighborhood Hits	84	Shared Neighborhood Hits	38
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.248608 (rank : 34)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	40
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.245715 (rank : 35)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	43
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.217548 (rank : 36)	θ value	0.0113563 (rank : 31)
Query Neighborhood Hits	135	Target Neighborhood Hits	109	Shared Neighborhood Hits	62
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNB2_HUMAN
NC score	0.197786 (rank : 37)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	135	Target Neighborhood Hits	212	Shared Neighborhood Hits	62
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNV2_HUMAN
NC score	0.197135 (rank : 38)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	135	Target Neighborhood Hits	137	Shared Neighborhood Hits	61
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNS2_MOUSE
NC score	0.189779 (rank : 39)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	63
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.184566 (rank : 40)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	135	Target Neighborhood Hits	129	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.177025 (rank : 41)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	63
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.176887 (rank : 42)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	135	Target Neighborhood Hits	169	Shared Neighborhood Hits	62
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND3_MOUSE
NC score	0.163118 (rank : 43)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.162978 (rank : 44)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	135	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS3_HUMAN
NC score	0.156037 (rank : 45)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	135	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND2_MOUSE
NC score	0.155276 (rank : 46)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	135	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.155114 (rank : 47)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	135	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.136555 (rank : 48)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	135	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.134626 (rank : 49)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	135	Target Neighborhood Hits	160	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

TPTE2_HUMAN
NC score	0.129866 (rank : 50)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	135	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNC1_HUMAN
NC score	0.128919 (rank : 51)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	58
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.126614 (rank : 52)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	135	Target Neighborhood Hits	133	Shared Neighborhood Hits	58
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNS1_HUMAN
NC score	0.123835 (rank : 53)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	135	Target Neighborhood Hits	116	Shared Neighborhood Hits	61
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_HUMAN
NC score	0.114002 (rank : 54)	θ value	0.0252991 (rank : 32)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	57
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS1_MOUSE
NC score	0.106632 (rank : 55)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	135	Target Neighborhood Hits	114	Shared Neighborhood Hits	55
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC4_MOUSE
NC score	0.106469 (rank : 56)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	135	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.104609 (rank : 57)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	135	Target Neighborhood Hits	256	Shared Neighborhood Hits	57
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.102305 (rank : 58)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	135	Target Neighborhood Hits	173	Shared Neighborhood Hits	56
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PKDRE_HUMAN
NC score	0.097757 (rank : 59)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	135	Target Neighborhood Hits	64	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TPTE_HUMAN
NC score	0.086284 (rank : 60)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	135	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

TRPV3_HUMAN
NC score	0.086090 (rank : 61)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	135	Target Neighborhood Hits	198	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCNA1_MOUSE
NC score	0.080894 (rank : 62)	θ value	0.0431538 (rank : 36)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	46
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.079537 (rank : 63)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	135	Target Neighborhood Hits	104	Shared Neighborhood Hits	45
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNG3_MOUSE
NC score	0.078657 (rank : 64)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	49
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
NC score	0.078435 (rank : 65)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA2_MOUSE
NC score	0.078011 (rank : 66)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	135	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.077179 (rank : 67)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNQ4_HUMAN
NC score	0.075006 (rank : 68)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	135	Target Neighborhood Hits	136	Shared Neighborhood Hits	45
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNA6_MOUSE
NC score	0.074927 (rank : 69)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	135	Target Neighborhood Hits	106	Shared Neighborhood Hits	45
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA6_HUMAN
NC score	0.071763 (rank : 70)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	135	Target Neighborhood Hits	100	Shared Neighborhood Hits	42
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_MOUSE
NC score	0.071493 (rank : 71)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	135	Target Neighborhood Hits	119	Shared Neighborhood Hits	42
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

PKDRE_MOUSE
NC score	0.070325 (rank : 72)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	135	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNA3_HUMAN
NC score	0.070266 (rank : 73)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
NC score	0.069688 (rank : 74)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.065813 (rank : 75)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	135	Target Neighborhood Hits	124	Shared Neighborhood Hits	38
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ1_MOUSE
NC score	0.064037 (rank : 76)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	135	Target Neighborhood Hits	175	Shared Neighborhood Hits	43
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

TRPC1_MOUSE
NC score	0.057228 (rank : 77)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	135	Target Neighborhood Hits	87	Shared Neighborhood Hits	17
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.057140 (rank : 78)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	135	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPV3_MOUSE
NC score	0.056818 (rank : 79)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	135	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

KCNA4_MOUSE
NC score	0.056192 (rank : 80)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	135	Target Neighborhood Hits	98	Shared Neighborhood Hits	34
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.055659 (rank : 81)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	135	Target Neighborhood Hits	108	Shared Neighborhood Hits	34
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ1_HUMAN
NC score	0.055557 (rank : 82)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	39
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNG1_HUMAN
NC score	0.053167 (rank : 83)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	135	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

TRPV4_MOUSE
NC score	0.052805 (rank : 84)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	135	Target Neighborhood Hits	117	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

CABP5_MOUSE
NC score	0.052512 (rank : 85)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	135	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

KCNQ5_HUMAN
NC score	0.051970 (rank : 86)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	135	Target Neighborhood Hits	163	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

TRPV4_HUMAN
NC score	0.051454 (rank : 87)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	135	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPM8_MOUSE
NC score	0.041875 (rank : 88)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	135	Target Neighborhood Hits	58	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

MEPE_HUMAN
NC score	0.039495 (rank : 89)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	135	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

TRPM8_HUMAN
NC score	0.035930 (rank : 90)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	135	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

KCMA1_MOUSE
NC score	0.031766 (rank : 91)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	135	Target Neighborhood Hits	94	Shared Neighborhood Hits	37
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.031710 (rank : 92)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	135	Target Neighborhood Hits	96	Shared Neighborhood Hits	37
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

CALB2_MOUSE
NC score	0.027071 (rank : 93)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	135	Target Neighborhood Hits	141	Shared Neighborhood Hits	16
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CALB2_HUMAN
NC score	0.026840 (rank : 94)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	135	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

SEGN_HUMAN
NC score	0.026503 (rank : 95)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	135	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

TRPV1_MOUSE
NC score	0.021245 (rank : 96)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	135	Target Neighborhood Hits	189	Shared Neighborhood Hits	14
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPM2_MOUSE
NC score	0.019774 (rank : 97)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	135	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

ZN318_HUMAN
NC score	0.019689 (rank : 98)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	135	Target Neighborhood Hits	497	Shared Neighborhood Hits	19
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

KCNH2_MOUSE
NC score	0.019201 (rank : 99)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	135	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

NPM2_HUMAN
NC score	0.018418 (rank : 100)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	135	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	Q86SE8	Gene names	NPM2
Domain Architecture
Description	Nucleoplasmin-2.

KCNH2_HUMAN
NC score	0.018011 (rank : 101)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	135	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

TRPM2_HUMAN
NC score	0.016592 (rank : 102)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	135	Target Neighborhood Hits	64	Shared Neighborhood Hits	10
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

SEGN_MOUSE
NC score	0.016543 (rank : 103)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	135	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

DZIP1_MOUSE
NC score	0.013397 (rank : 104)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	135	Target Neighborhood Hits	530	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

RIF1_MOUSE
NC score	0.012981 (rank : 105)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	135	Target Neighborhood Hits	315	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PR54, Q6T8D9, Q7TPD8, Q8BTU2, Q8C408, Q9CS77	Gene names	Rif1
Domain Architecture	No domain graphic available
Description	Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) (mRif1).

ZC11A_HUMAN
NC score	0.012284 (rank : 106)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	135	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

MKL1_MOUSE
NC score	0.012028 (rank : 107)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	135	Target Neighborhood Hits	667	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CT2NL_HUMAN
NC score	0.011657 (rank : 108)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	135	Target Neighborhood Hits	1059	Shared Neighborhood Hits	35
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

I17RA_MOUSE
NC score	0.010994 (rank : 109)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	135	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q60943	Gene names	IL17ra, Il17r
Domain Architecture	No domain graphic available
Description	Interleukin-17 receptor A precursor (IL-17 receptor).

MAP1B_MOUSE
NC score	0.010640 (rank : 110)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	135	Target Neighborhood Hits	977	Shared Neighborhood Hits	32
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RXINP_MOUSE
NC score	0.010458 (rank : 111)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

PIGW_HUMAN
NC score	0.009703 (rank : 112)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	135	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q7Z7B1, Q8N9G3	Gene names	PIGW
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-glycan biosynthesis class W protein (EC 2.3.-.-) (PIG-W).

TAXB1_HUMAN
NC score	0.009494 (rank : 113)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	135	Target Neighborhood Hits	829	Shared Neighborhood Hits	32
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

ITPR1_HUMAN
NC score	0.009390 (rank : 114)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	135	Target Neighborhood Hits	90	Shared Neighborhood Hits	9
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.009375 (rank : 115)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	135	Target Neighborhood Hits	99	Shared Neighborhood Hits	9
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

TMF1_HUMAN
NC score	0.008353 (rank : 116)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	135	Target Neighborhood Hits	987	Shared Neighborhood Hits	32
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TPR_HUMAN
NC score	0.008205 (rank : 117)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	135	Target Neighborhood Hits	1921	Shared Neighborhood Hits	46
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CKAP4_MOUSE
NC score	0.007957 (rank : 118)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	135	Target Neighborhood Hits	596	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CROCC_MOUSE
NC score	0.007946 (rank : 119)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	135	Target Neighborhood Hits	1460	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MYH4_HUMAN
NC score	0.007869 (rank : 120)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	135	Target Neighborhood Hits	1377	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH13_HUMAN
NC score	0.007861 (rank : 121)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	135	Target Neighborhood Hits	1504	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MAP1B_HUMAN
NC score	0.007780 (rank : 122)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	135	Target Neighborhood Hits	903	Shared Neighborhood Hits	24
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

RB6I2_HUMAN
NC score	0.007743 (rank : 123)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	135	Target Neighborhood Hits	1584	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SMC4_MOUSE
NC score	0.007608 (rank : 124)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	135	Target Neighborhood Hits	830	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG47, Q8BTS7, Q8BTY9, Q99K21	Gene names	Smc4l1, Capc, Smc4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (XCAP-C homolog).

CP135_HUMAN
NC score	0.007413 (rank : 125)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	135	Target Neighborhood Hits	1290	Shared Neighborhood Hits	32
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH6_HUMAN
NC score	0.007047 (rank : 126)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	135	Target Neighborhood Hits	1426	Shared Neighborhood Hits	35
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
NC score	0.007043 (rank : 127)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	135	Target Neighborhood Hits	1501	Shared Neighborhood Hits	34
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CP135_MOUSE
NC score	0.006995 (rank : 128)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	135	Target Neighborhood Hits	1278	Shared Neighborhood Hits	34
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CF152_HUMAN
NC score	0.006983 (rank : 129)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	135	Target Neighborhood Hits	704	Shared Neighborhood Hits	34
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

SMC1A_HUMAN
NC score	0.006939 (rank : 130)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	135	Target Neighborhood Hits	1346	Shared Neighborhood Hits	33
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

MYH7_HUMAN
NC score	0.006763 (rank : 131)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	135	Target Neighborhood Hits	1559	Shared Neighborhood Hits	32
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

ERC2_MOUSE
NC score	0.006729 (rank : 132)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	135	Target Neighborhood Hits	1166	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

ERC2_HUMAN
NC score	0.006711 (rank : 133)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	135	Target Neighborhood Hits	1156	Shared Neighborhood Hits	31
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

SMC1A_MOUSE
NC score	0.006657 (rank : 134)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	135	Target Neighborhood Hits	1384	Shared Neighborhood Hits	34
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TMCC3_HUMAN
NC score	0.006352 (rank : 135)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	135	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULS5, Q8IWB2	Gene names	TMCC3, KIAA1145
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 3.

NCKX1_HUMAN
NC score	0.006104 (rank : 136)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	135	Target Neighborhood Hits	223	Shared Neighborhood Hits	5
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

MYH9_HUMAN
NC score	0.005688 (rank : 137)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	135	Target Neighborhood Hits	1762	Shared Neighborhood Hits	39
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TRPA1_HUMAN
NC score	0.005546 (rank : 138)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	135	Target Neighborhood Hits	339	Shared Neighborhood Hits	11
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

MYH10_HUMAN
NC score	0.005413 (rank : 139)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	135	Target Neighborhood Hits	1620	Shared Neighborhood Hits	36
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.005279 (rank : 140)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	135	Target Neighborhood Hits	1612	Shared Neighborhood Hits	35
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH9_MOUSE
NC score	0.005206 (rank : 141)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	135	Target Neighborhood Hits	1829	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

NKTR_HUMAN
NC score	0.004460 (rank : 142)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	135	Target Neighborhood Hits	658	Shared Neighborhood Hits	17
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

WWP1_HUMAN
NC score	0.004304 (rank : 143)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	135	Target Neighborhood Hits	262	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

OAT6_MOUSE
NC score	0.004112 (rank : 144)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	135	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UJ1	Gene names	Slc22a20, Gm963, Oat6
Domain Architecture	No domain graphic available
Description	Solute carrier family 22 member 20 (Organic anion transporter 6).

CENPF_HUMAN
NC score	0.003758 (rank : 145)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	135	Target Neighborhood Hits	1932	Shared Neighborhood Hits	38
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PLEC1_HUMAN
NC score	0.003399 (rank : 146)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	135	Target Neighborhood Hits	1326	Shared Neighborhood Hits	30
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

DDX23_HUMAN
NC score	0.003061 (rank : 147)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	135	Target Neighborhood Hits	486	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

CALM_HUMAN
NC score	0.002530 (rank : 148)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	135	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.002530 (rank : 149)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	135	Target Neighborhood Hits	232	Shared Neighborhood Hits	7
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

KIF3A_HUMAN
NC score	0.002446 (rank : 150)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	135	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

DSPP_HUMAN
NC score	0.002415 (rank : 151)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	135	Target Neighborhood Hits	645	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GPR64_HUMAN
NC score	0.002406 (rank : 152)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	135	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

MOR2A_MOUSE
NC score	0.002304 (rank : 153)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	135	Target Neighborhood Hits	220	Shared Neighborhood Hits	7
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

HUWE1_HUMAN
NC score	0.002016 (rank : 154)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	135	Target Neighborhood Hits	443	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

WWP1_MOUSE
NC score	0.001973 (rank : 155)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	135	Target Neighborhood Hits	138	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BZZ3, Q8BIV9, Q8VDP8	Gene names	Wwp1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1).

DRD1_MOUSE
NC score	-0.000808 (rank : 156)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	135	Target Neighborhood Hits	733	Shared Neighborhood Hits	3
SwissProt Accessions	Q61616, Q8C8P8	Gene names	Drd1, Drd1a, Gpcr15
Domain Architecture
Description	D(1A) dopamine receptor.

DRD1_HUMAN
NC score	-0.001323 (rank : 157)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	135	Target Neighborhood Hits	750	Shared Neighborhood Hits	3
SwissProt Accessions	P21728, Q4QRJ0	Gene names	DRD1
Domain Architecture
Description	D(1A) dopamine receptor.