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Network neighborhood for query Sequence : CAC1I_HUMAN

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CAC1I_HUMAN
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1G_HUMAN
θ value	0 (rank : 1)	NC score	0.951967 (rank : 4)
Query Neighborhood Hits	138	Target Neighborhood Hits	587	Shared Neighborhood Hits	78
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_HUMAN
θ value	0 (rank : 2)	NC score	0.977156 (rank : 3)
Query Neighborhood Hits	138	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
θ value	0 (rank : 3)	NC score	0.983744 (rank : 2)
Query Neighborhood Hits	138	Target Neighborhood Hits	230	Shared Neighborhood Hits	76
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	138	Target Neighborhood Hits	138	Shared Neighborhood Hits	138
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_HUMAN
θ value	6.95003e-85 (rank : 5)	NC score	0.913015 (rank : 5)
Query Neighborhood Hits	138	Target Neighborhood Hits	111	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN3A_HUMAN
θ value	5.8972e-76 (rank : 6)	NC score	0.897325 (rank : 15)
Query Neighborhood Hits	138	Target Neighborhood Hits	115	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN9A_HUMAN
θ value	1.31376e-75 (rank : 7)	NC score	0.893607 (rank : 21)
Query Neighborhood Hits	138	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SC11A_MOUSE
θ value	6.52014e-75 (rank : 8)	NC score	0.909697 (rank : 6)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1S_MOUSE
θ value	1.89707e-74 (rank : 9)	NC score	0.901279 (rank : 11)
Query Neighborhood Hits	138	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN2A_HUMAN
θ value	3.23591e-74 (rank : 10)	NC score	0.893438 (rank : 22)
Query Neighborhood Hits	138	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

CAC1C_MOUSE
θ value	7.20884e-74 (rank : 11)	NC score	0.894870 (rank : 20)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SCN4A_HUMAN
θ value	2.73936e-73 (rank : 12)	NC score	0.903197 (rank : 9)
Query Neighborhood Hits	138	Target Neighborhood Hits	133	Shared Neighborhood Hits	68
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN1A_HUMAN
θ value	3.57772e-73 (rank : 13)	NC score	0.893084 (rank : 23)
Query Neighborhood Hits	138	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1F_MOUSE
θ value	1.96316e-71 (rank : 14)	NC score	0.896459 (rank : 17)
Query Neighborhood Hits	138	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	1.96316e-71 (rank : 15)	NC score	0.900192 (rank : 13)
Query Neighborhood Hits	138	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN8A_HUMAN
θ value	9.74306e-71 (rank : 16)	NC score	0.891536 (rank : 26)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1D_HUMAN
θ value	1.27248e-70 (rank : 17)	NC score	0.900685 (rank : 12)
Query Neighborhood Hits	138	Target Neighborhood Hits	118	Shared Neighborhood Hits	62
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

SCN8A_MOUSE
θ value	1.27248e-70 (rank : 18)	NC score	0.889338 (rank : 29)
Query Neighborhood Hits	138	Target Neighborhood Hits	136	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1B_HUMAN
θ value	4.83544e-70 (rank : 19)	NC score	0.896546 (rank : 16)
Query Neighborhood Hits	138	Target Neighborhood Hits	257	Shared Neighborhood Hits	69
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_HUMAN
θ value	6.31527e-70 (rank : 20)	NC score	0.896416 (rank : 18)
Query Neighborhood Hits	138	Target Neighborhood Hits	141	Shared Neighborhood Hits	63
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_MOUSE
θ value	3.13423e-69 (rank : 21)	NC score	0.892839 (rank : 24)
Query Neighborhood Hits	138	Target Neighborhood Hits	351	Shared Neighborhood Hits	71
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SC10A_MOUSE
θ value	4.09345e-69 (rank : 22)	NC score	0.892828 (rank : 25)
Query Neighborhood Hits	138	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1E_HUMAN
θ value	2.03155e-68 (rank : 23)	NC score	0.904259 (rank : 8)
Query Neighborhood Hits	138	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	2.65329e-68 (rank : 24)	NC score	0.904291 (rank : 7)
Query Neighborhood Hits	138	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN5A_HUMAN
θ value	5.91091e-68 (rank : 25)	NC score	0.901370 (rank : 10)
Query Neighborhood Hits	138	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1C_HUMAN
θ value	7.71989e-68 (rank : 26)	NC score	0.888878 (rank : 30)
Query Neighborhood Hits	138	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

SC10A_HUMAN
θ value	1.90147e-66 (rank : 27)	NC score	0.890498 (rank : 28)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CAC1A_HUMAN
θ value	2.4834e-66 (rank : 28)	NC score	0.890930 (rank : 27)
Query Neighborhood Hits	138	Target Neighborhood Hits	387	Shared Neighborhood Hits	77
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	9.43692e-66 (rank : 29)	NC score	0.898151 (rank : 14)
Query Neighborhood Hits	138	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN7A_HUMAN
θ value	3.84025e-59 (rank : 30)	NC score	0.895687 (rank : 19)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

KCNB1_HUMAN
θ value	3.41135e-07 (rank : 31)	NC score	0.244408 (rank : 42)
Query Neighborhood Hits	138	Target Neighborhood Hits	169	Shared Neighborhood Hits	64
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	3.41135e-07 (rank : 32)	NC score	0.244474 (rank : 41)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNV2_HUMAN
θ value	4.45536e-07 (rank : 33)	NC score	0.270289 (rank : 36)
Query Neighborhood Hits	138	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
θ value	4.92598e-06 (rank : 34)	NC score	0.255048 (rank : 38)
Query Neighborhood Hits	138	Target Neighborhood Hits	212	Shared Neighborhood Hits	64
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

PK2L1_HUMAN
θ value	3.19293e-05 (rank : 35)	NC score	0.312251 (rank : 32)
Query Neighborhood Hits	138	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

TPTE2_HUMAN
θ value	3.19293e-05 (rank : 36)	NC score	0.192140 (rank : 48)
Query Neighborhood Hits	138	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS2_MOUSE
θ value	7.1131e-05 (rank : 37)	NC score	0.250472 (rank : 39)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	65
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	9.29e-05 (rank : 38)	NC score	0.245974 (rank : 40)
Query Neighborhood Hits	138	Target Neighborhood Hits	129	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS1_MOUSE
θ value	0.00134147 (rank : 39)	NC score	0.180481 (rank : 51)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

PK2L2_HUMAN
θ value	0.00228821 (rank : 40)	NC score	0.328321 (rank : 31)
Query Neighborhood Hits	138	Target Neighborhood Hits	90	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNC4_HUMAN
θ value	0.00390308 (rank : 41)	NC score	0.167895 (rank : 55)
Query Neighborhood Hits	138	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNF1_HUMAN
θ value	0.00390308 (rank : 42)	NC score	0.267766 (rank : 37)
Query Neighborhood Hits	138	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

TPTE_HUMAN
θ value	0.00390308 (rank : 43)	NC score	0.141845 (rank : 59)
Query Neighborhood Hits	138	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNS1_HUMAN
θ value	0.00665767 (rank : 44)	NC score	0.191897 (rank : 49)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS3_HUMAN
θ value	0.00665767 (rank : 45)	NC score	0.215523 (rank : 43)
Query Neighborhood Hits	138	Target Neighborhood Hits	125	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

PK2L2_MOUSE
θ value	0.00869519 (rank : 46)	NC score	0.294266 (rank : 33)
Query Neighborhood Hits	138	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNC1_MOUSE
θ value	0.0113563 (rank : 47)	NC score	0.180037 (rank : 52)
Query Neighborhood Hits	138	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNQ5_HUMAN
θ value	0.0113563 (rank : 48)	NC score	0.090878 (rank : 78)
Query Neighborhood Hits	138	Target Neighborhood Hits	163	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNC1_HUMAN
θ value	0.0148317 (rank : 49)	NC score	0.181487 (rank : 50)
Query Neighborhood Hits	138	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

PKD2_MOUSE
θ value	0.0148317 (rank : 50)	NC score	0.289000 (rank : 34)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
θ value	0.0563607 (rank : 51)	NC score	0.275273 (rank : 35)
Query Neighborhood Hits	138	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

AFF1_HUMAN
θ value	0.0736092 (rank : 52)	NC score	0.027018 (rank : 96)
Query Neighborhood Hits	138	Target Neighborhood Hits	506	Shared Neighborhood Hits	19
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

KCNC4_MOUSE
θ value	0.0736092 (rank : 53)	NC score	0.156776 (rank : 56)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

ZN409_HUMAN
θ value	0.0961366 (rank : 54)	NC score	0.011620 (rank : 117)
Query Neighborhood Hits	138	Target Neighborhood Hits	842	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

KCNC3_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.154465 (rank : 57)
Query Neighborhood Hits	138	Target Neighborhood Hits	256	Shared Neighborhood Hits	65
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

OGFR_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.018245 (rank : 104)
Query Neighborhood Hits	138	Target Neighborhood Hits	1582	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PCLO_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.023389 (rank : 98)
Query Neighborhood Hits	138	Target Neighborhood Hits	2046	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

KCNC3_MOUSE
θ value	0.279714 (rank : 58)	NC score	0.152126 (rank : 58)
Query Neighborhood Hits	138	Target Neighborhood Hits	173	Shared Neighborhood Hits	62
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

MEGF6_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.000924 (rank : 147)
Query Neighborhood Hits	138	Target Neighborhood Hits	671	Shared Neighborhood Hits	5
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KCND2_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.196803 (rank : 47)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.62314 (rank : 61)	NC score	0.197157 (rank : 46)
Query Neighborhood Hits	138	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

ACE2_MOUSE
θ value	0.813845 (rank : 62)	NC score	0.014894 (rank : 110)
Query Neighborhood Hits	138	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

MLL3_MOUSE
θ value	0.813845 (rank : 63)	NC score	0.013473 (rank : 112)
Query Neighborhood Hits	138	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NCOA6_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.017574 (rank : 106)
Query Neighborhood Hits	138	Target Neighborhood Hits	1202	Shared Neighborhood Hits	27
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.017967 (rank : 105)
Query Neighborhood Hits	138	Target Neighborhood Hits	1076	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

IWS1_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.030924 (rank : 92)
Query Neighborhood Hits	138	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KCND3_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.199939 (rank : 45)
Query Neighborhood Hits	138	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.200127 (rank : 44)
Query Neighborhood Hits	138	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

TRPM2_MOUSE
θ value	1.06291 (rank : 69)	NC score	0.021989 (rank : 99)
Query Neighborhood Hits	138	Target Neighborhood Hits	61	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TTBK1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.001525 (rank : 144)
Query Neighborhood Hits	138	Target Neighborhood Hits	1058	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

AMPH_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.014663 (rank : 111)
Query Neighborhood Hits	138	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

KCNA1_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.116636 (rank : 62)
Query Neighborhood Hits	138	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCND1_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.177171 (rank : 54)
Query Neighborhood Hits	138	Target Neighborhood Hits	160	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

BCOR_MOUSE
θ value	1.81305 (rank : 74)	NC score	0.007237 (rank : 129)
Query Neighborhood Hits	138	Target Neighborhood Hits	521	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

FYV1_HUMAN
θ value	1.81305 (rank : 75)	NC score	0.010852 (rank : 119)
Query Neighborhood Hits	138	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

HPS4_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.014951 (rank : 109)
Query Neighborhood Hits	138	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

KCNG3_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.136844 (rank : 60)
Query Neighborhood Hits	138	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

LGR4_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.000618 (rank : 148)
Query Neighborhood Hits	138	Target Neighborhood Hits	481	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

TAF2_HUMAN
θ value	1.81305 (rank : 79)	NC score	0.012647 (rank : 114)
Query Neighborhood Hits	138	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1X5, O43487, O43604, O60668, Q86WW7, Q8IWK4	Gene names	TAF2, CIF150, TAF2B
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (TBP-associated factor 150 kDa) (TAFII-150) (TAFII150) (150 kDa cofactor of initiator function).

ATX1_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.018473 (rank : 103)
Query Neighborhood Hits	138	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

BAT3_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.028897 (rank : 94)
Query Neighborhood Hits	138	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

CGRE1_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.017429 (rank : 107)
Query Neighborhood Hits	138	Target Neighborhood Hits	354	Shared Neighborhood Hits	13
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

HES1_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.009084 (rank : 125)
Query Neighborhood Hits	138	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

KCNA1_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.114362 (rank : 63)
Query Neighborhood Hits	138	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCND1_MOUSE
θ value	2.36792 (rank : 85)	NC score	0.177583 (rank : 53)
Query Neighborhood Hits	138	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

MCLN2_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.062362 (rank : 87)
Query Neighborhood Hits	138	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

RHG25_MOUSE
θ value	2.36792 (rank : 87)	NC score	0.003996 (rank : 137)
Query Neighborhood Hits	138	Target Neighborhood Hits	492	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

S36A1_MOUSE
θ value	2.36792 (rank : 88)	NC score	0.033148 (rank : 91)
Query Neighborhood Hits	138	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

TGON1_MOUSE
θ value	2.36792 (rank : 89)	NC score	0.011822 (rank : 116)
Query Neighborhood Hits	138	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

TRPM2_HUMAN
θ value	2.36792 (rank : 90)	NC score	0.015917 (rank : 108)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

ATX1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.021244 (rank : 100)
Query Neighborhood Hits	138	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

DCJ14_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.008834 (rank : 126)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q6Y2X3, Q66K17, Q96N59, Q96T63	Gene names	DNAJC14, DRIP78
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14 (Dopamine receptor-interacting protein of 78 kDa) (DRiP78).

EPN2_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.009808 (rank : 121)
Query Neighborhood Hits	138	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

HDAC4_HUMAN
θ value	3.0926 (rank : 94)	NC score	0.004010 (rank : 136)
Query Neighborhood Hits	138	Target Neighborhood Hits	390	Shared Neighborhood Hits	7
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

KCNA3_HUMAN
θ value	3.0926 (rank : 95)	NC score	0.101715 (rank : 72)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

LPP_HUMAN
θ value	3.0926 (rank : 96)	NC score	0.002321 (rank : 140)
Query Neighborhood Hits	138	Target Neighborhood Hits	775	Shared Neighborhood Hits	14
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

T240L_HUMAN
θ value	3.0926 (rank : 97)	NC score	0.019025 (rank : 102)
Query Neighborhood Hits	138	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ACM3_MOUSE
θ value	4.03905 (rank : 98)	NC score	-0.003274 (rank : 153)
Query Neighborhood Hits	138	Target Neighborhood Hits	932	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERZ3, Q64055	Gene names	Chrm3, Chrm-3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3 (Mm3 mAChR).

K0040_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.019615 (rank : 101)
Query Neighborhood Hits	138	Target Neighborhood Hits	2	Shared Neighborhood Hits	2
SwissProt Accessions	Q15053	Gene names	KIAA0040
Domain Architecture	No domain graphic available
Description	Protein KIAA0040.

KCNA5_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.102502 (rank : 69)
Query Neighborhood Hits	138	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNG3_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.135583 (rank : 61)
Query Neighborhood Hits	138	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNQ1_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.100409 (rank : 73)
Query Neighborhood Hits	138	Target Neighborhood Hits	175	Shared Neighborhood Hits	46
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

RECQ5_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.008107 (rank : 127)
Query Neighborhood Hits	138	Target Neighborhood Hits	390	Shared Neighborhood Hits	16
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RIMB1_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.001863 (rank : 142)
Query Neighborhood Hits	138	Target Neighborhood Hits	1479	Shared Neighborhood Hits	22
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZN750_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.013065 (rank : 113)
Query Neighborhood Hits	138	Target Neighborhood Hits	346	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

CFAH_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.004156 (rank : 135)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CSPG3_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.000292 (rank : 150)
Query Neighborhood Hits	138	Target Neighborhood Hits	657	Shared Neighborhood Hits	14
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EP15_HUMAN
θ value	5.27518 (rank : 108)	NC score	-0.001761 (rank : 151)
Query Neighborhood Hits	138	Target Neighborhood Hits	1021	Shared Neighborhood Hits	7
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

FHR1_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.005607 (rank : 131)
Query Neighborhood Hits	138	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FYV1_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.009119 (rank : 124)
Query Neighborhood Hits	138	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

K1383_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.011158 (rank : 118)
Query Neighborhood Hits	138	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

LEUK_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.012544 (rank : 115)
Query Neighborhood Hits	138	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

RPTN_MOUSE
θ value	5.27518 (rank : 113)	NC score	0.010395 (rank : 120)
Query Neighborhood Hits	138	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

ZN509_MOUSE
θ value	5.27518 (rank : 114)	NC score	-0.005136 (rank : 155)
Query Neighborhood Hits	138	Target Neighborhood Hits	990	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

ZN598_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.009300 (rank : 122)
Query Neighborhood Hits	138	Target Neighborhood Hits	339	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

BAT3_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.028288 (rank : 95)
Query Neighborhood Hits	138	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

KCNA5_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.097583 (rank : 77)
Query Neighborhood Hits	138	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

LUZP1_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.001367 (rank : 146)
Query Neighborhood Hits	138	Target Neighborhood Hits	940	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MARK2_HUMAN
θ value	6.88961 (rank : 119)	NC score	-0.005271 (rank : 156)
Query Neighborhood Hits	138	Target Neighborhood Hits	1056	Shared Neighborhood Hits	10
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

RELN_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.004802 (rank : 133)
Query Neighborhood Hits	138	Target Neighborhood Hits	233	Shared Neighborhood Hits	5
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

STRN4_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.000299 (rank : 149)
Query Neighborhood Hits	138	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

TDRD6_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.007636 (rank : 128)
Query Neighborhood Hits	138	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

ZIMP7_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.009290 (rank : 123)
Query Neighborhood Hits	138	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ZN597_HUMAN
θ value	6.88961 (rank : 124)	NC score	-0.004863 (rank : 154)
Query Neighborhood Hits	138	Target Neighborhood Hits	722	Shared Neighborhood Hits	5
SwissProt Accessions	Q96LX8	Gene names	ZNF597
Domain Architecture	No domain graphic available
Description	Zinc finger protein 597.

ADA12_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.001802 (rank : 143)
Query Neighborhood Hits	138	Target Neighborhood Hits	474	Shared Neighborhood Hits	12
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ANKR9_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.005387 (rank : 132)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAZ2A_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.003379 (rank : 139)
Query Neighborhood Hits	138	Target Neighborhood Hits	780	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BIRC6_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.003399 (rank : 138)
Query Neighborhood Hits	138	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

BSN_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.030250 (rank : 93)
Query Neighborhood Hits	138	Target Neighborhood Hits	2057	Shared Neighborhood Hits	45
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CALD1_HUMAN
θ value	8.99809 (rank : 130)	NC score	-0.002184 (rank : 152)
Query Neighborhood Hits	138	Target Neighborhood Hits	959	Shared Neighborhood Hits	8
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CO5A3_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.001413 (rank : 145)
Query Neighborhood Hits	138	Target Neighborhood Hits	433	Shared Neighborhood Hits	14
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

DIDO1_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.024115 (rank : 97)
Query Neighborhood Hits	138	Target Neighborhood Hits	960	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

FOG1_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.004200 (rank : 134)
Query Neighborhood Hits	138	Target Neighborhood Hits	1237	Shared Neighborhood Hits	31
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GON4L_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.006204 (rank : 130)
Query Neighborhood Hits	138	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

KCNA2_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.111128 (rank : 64)
Query Neighborhood Hits	138	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNQ3_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.076790 (rank : 82)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	42
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.076013 (rank : 83)
Query Neighborhood Hits	138	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

PPE2_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.002224 (rank : 141)
Query Neighborhood Hits	138	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O14830, O14831	Gene names	PPEF2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

KCMA1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.050725 (rank : 90)
Query Neighborhood Hits	138	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.050842 (rank : 89)
Query Neighborhood Hits	138	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.109501 (rank : 65)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA3_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.099172 (rank : 75)
Query Neighborhood Hits	138	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.088067 (rank : 81)
Query Neighborhood Hits	138	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.088394 (rank : 80)
Query Neighborhood Hits	138	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA6_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.103988 (rank : 68)
Query Neighborhood Hits	138	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.106931 (rank : 66)
Query Neighborhood Hits	138	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.105748 (rank : 67)
Query Neighborhood Hits	138	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.101760 (rank : 71)
Query Neighborhood Hits	138	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.099408 (rank : 74)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.089468 (rank : 79)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.074944 (rank : 84)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	39
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.072092 (rank : 85)
Query Neighborhood Hits	138	Target Neighborhood Hits	163	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.101761 (rank : 70)
Query Neighborhood Hits	138	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

PKDRE_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.098614 (rank : 76)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PKDRE_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.069511 (rank : 86)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TRPV3_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.062206 (rank : 88)
Query Neighborhood Hits	138	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1I_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	138	Target Neighborhood Hits	138	Shared Neighborhood Hits	138
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.983744 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	138	Target Neighborhood Hits	230	Shared Neighborhood Hits	76
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.977156 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	138	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1G_HUMAN
NC score	0.951967 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	138	Target Neighborhood Hits	587	Shared Neighborhood Hits	78
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC11A_HUMAN
NC score	0.913015 (rank : 5)	θ value	6.95003e-85 (rank : 5)
Query Neighborhood Hits	138	Target Neighborhood Hits	111	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
NC score	0.909697 (rank : 6)	θ value	6.52014e-75 (rank : 8)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1E_MOUSE
NC score	0.904291 (rank : 7)	θ value	2.65329e-68 (rank : 24)
Query Neighborhood Hits	138	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.904259 (rank : 8)	θ value	2.03155e-68 (rank : 23)
Query Neighborhood Hits	138	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN4A_HUMAN
NC score	0.903197 (rank : 9)	θ value	2.73936e-73 (rank : 12)
Query Neighborhood Hits	138	Target Neighborhood Hits	133	Shared Neighborhood Hits	68
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
NC score	0.901370 (rank : 10)	θ value	5.91091e-68 (rank : 25)
Query Neighborhood Hits	138	Target Neighborhood Hits	145	Shared Neighborhood Hits	62
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1S_MOUSE
NC score	0.901279 (rank : 11)	θ value	1.89707e-74 (rank : 9)
Query Neighborhood Hits	138	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1D_HUMAN
NC score	0.900685 (rank : 12)	θ value	1.27248e-70 (rank : 17)
Query Neighborhood Hits	138	Target Neighborhood Hits	118	Shared Neighborhood Hits	62
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_HUMAN
NC score	0.900192 (rank : 13)	θ value	1.96316e-71 (rank : 15)
Query Neighborhood Hits	138	Target Neighborhood Hits	92	Shared Neighborhood Hits	59
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1A_MOUSE
NC score	0.898151 (rank : 14)	θ value	9.43692e-66 (rank : 29)
Query Neighborhood Hits	138	Target Neighborhood Hits	267	Shared Neighborhood Hits	75
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN3A_HUMAN
NC score	0.897325 (rank : 15)	θ value	5.8972e-76 (rank : 6)
Query Neighborhood Hits	138	Target Neighborhood Hits	115	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1B_HUMAN
NC score	0.896546 (rank : 16)	θ value	4.83544e-70 (rank : 19)
Query Neighborhood Hits	138	Target Neighborhood Hits	257	Shared Neighborhood Hits	69
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_MOUSE
NC score	0.896459 (rank : 17)	θ value	1.96316e-71 (rank : 14)
Query Neighborhood Hits	138	Target Neighborhood Hits	142	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.896416 (rank : 18)	θ value	6.31527e-70 (rank : 20)
Query Neighborhood Hits	138	Target Neighborhood Hits	141	Shared Neighborhood Hits	63
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SCN7A_HUMAN
NC score	0.895687 (rank : 19)	θ value	3.84025e-59 (rank : 30)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1C_MOUSE
NC score	0.894870 (rank : 20)	θ value	7.20884e-74 (rank : 11)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	56
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SCN9A_HUMAN
NC score	0.893607 (rank : 21)	θ value	1.31376e-75 (rank : 7)
Query Neighborhood Hits	138	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN2A_HUMAN
NC score	0.893438 (rank : 22)	θ value	3.23591e-74 (rank : 10)
Query Neighborhood Hits	138	Target Neighborhood Hits	157	Shared Neighborhood Hits	57
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN1A_HUMAN
NC score	0.893084 (rank : 23)	θ value	3.57772e-73 (rank : 13)
Query Neighborhood Hits	138	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1B_MOUSE
NC score	0.892839 (rank : 24)	θ value	3.13423e-69 (rank : 21)
Query Neighborhood Hits	138	Target Neighborhood Hits	351	Shared Neighborhood Hits	71
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

SC10A_MOUSE
NC score	0.892828 (rank : 25)	θ value	4.09345e-69 (rank : 22)
Query Neighborhood Hits	138	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN8A_HUMAN
NC score	0.891536 (rank : 26)	θ value	9.74306e-71 (rank : 16)
Query Neighborhood Hits	138	Target Neighborhood Hits	135	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1A_HUMAN
NC score	0.890930 (rank : 27)	θ value	2.4834e-66 (rank : 28)
Query Neighborhood Hits	138	Target Neighborhood Hits	387	Shared Neighborhood Hits	77
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SC10A_HUMAN
NC score	0.890498 (rank : 28)	θ value	1.90147e-66 (rank : 27)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
NC score	0.889338 (rank : 29)	θ value	1.27248e-70 (rank : 18)
Query Neighborhood Hits	138	Target Neighborhood Hits	136	Shared Neighborhood Hits	61
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1C_HUMAN
NC score	0.888878 (rank : 30)	θ value	7.71989e-68 (rank : 26)
Query Neighborhood Hits	138	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.328321 (rank : 31)	θ value	0.00228821 (rank : 40)
Query Neighborhood Hits	138	Target Neighborhood Hits	90	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.312251 (rank : 32)	θ value	3.19293e-05 (rank : 35)
Query Neighborhood Hits	138	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.294266 (rank : 33)	θ value	0.00869519 (rank : 46)
Query Neighborhood Hits	138	Target Neighborhood Hits	84	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.289000 (rank : 34)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.275273 (rank : 35)	θ value	0.0563607 (rank : 51)
Query Neighborhood Hits	138	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNV2_HUMAN
NC score	0.270289 (rank : 36)	θ value	4.45536e-07 (rank : 33)
Query Neighborhood Hits	138	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNF1_HUMAN
NC score	0.267766 (rank : 37)	θ value	0.00390308 (rank : 42)
Query Neighborhood Hits	138	Target Neighborhood Hits	109	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNB2_HUMAN
NC score	0.255048 (rank : 38)	θ value	4.92598e-06 (rank : 34)
Query Neighborhood Hits	138	Target Neighborhood Hits	212	Shared Neighborhood Hits	64
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.250472 (rank : 39)	θ value	7.1131e-05 (rank : 37)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	65
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.245974 (rank : 40)	θ value	9.29e-05 (rank : 38)
Query Neighborhood Hits	138	Target Neighborhood Hits	129	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.244474 (rank : 41)	θ value	3.41135e-07 (rank : 32)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.244408 (rank : 42)	θ value	3.41135e-07 (rank : 31)
Query Neighborhood Hits	138	Target Neighborhood Hits	169	Shared Neighborhood Hits	64
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNS3_HUMAN
NC score	0.215523 (rank : 43)	θ value	0.00665767 (rank : 45)
Query Neighborhood Hits	138	Target Neighborhood Hits	125	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND3_MOUSE
NC score	0.200127 (rank : 44)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	138	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.199939 (rank : 45)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	138	Target Neighborhood Hits	162	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.197157 (rank : 46)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	138	Target Neighborhood Hits	156	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.196803 (rank : 47)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	138	Target Neighborhood Hits	154	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

TPTE2_HUMAN
NC score	0.192140 (rank : 48)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	138	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_HUMAN
NC score	0.191897 (rank : 49)	θ value	0.00665767 (rank : 44)
Query Neighborhood Hits	138	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.181487 (rank : 50)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	138	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNS1_MOUSE
NC score	0.180481 (rank : 51)	θ value	0.00134147 (rank : 39)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_MOUSE
NC score	0.180037 (rank : 52)	θ value	0.0113563 (rank : 47)
Query Neighborhood Hits	138	Target Neighborhood Hits	133	Shared Neighborhood Hits	60
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCND1_MOUSE
NC score	0.177583 (rank : 53)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	138	Target Neighborhood Hits	165	Shared Neighborhood Hits	63
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.177171 (rank : 54)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	138	Target Neighborhood Hits	160	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNC4_HUMAN
NC score	0.167895 (rank : 55)	θ value	0.00390308 (rank : 41)
Query Neighborhood Hits	138	Target Neighborhood Hits	141	Shared Neighborhood Hits	59
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
NC score	0.156776 (rank : 56)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	138	Target Neighborhood Hits	130	Shared Neighborhood Hits	59
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.154465 (rank : 57)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	138	Target Neighborhood Hits	256	Shared Neighborhood Hits	65
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.152126 (rank : 58)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	138	Target Neighborhood Hits	173	Shared Neighborhood Hits	62
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TPTE_HUMAN
NC score	0.141845 (rank : 59)	θ value	0.00390308 (rank : 43)
Query Neighborhood Hits	138	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNG3_HUMAN
NC score	0.136844 (rank : 60)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	138	Target Neighborhood Hits	91	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.135583 (rank : 61)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	138	Target Neighborhood Hits	91	Shared Neighborhood Hits	51
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA1_MOUSE
NC score	0.116636 (rank : 62)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	138	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.114362 (rank : 63)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	138	Target Neighborhood Hits	104	Shared Neighborhood Hits	47
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_MOUSE
NC score	0.111128 (rank : 64)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	138	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.109501 (rank : 65)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA6_MOUSE
NC score	0.106931 (rank : 66)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	138	Target Neighborhood Hits	106	Shared Neighborhood Hits	47
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
NC score	0.105748 (rank : 67)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	138	Target Neighborhood Hits	103	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA6_HUMAN
NC score	0.103988 (rank : 68)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	138	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_MOUSE
NC score	0.102502 (rank : 69)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	138	Target Neighborhood Hits	119	Shared Neighborhood Hits	48
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNQ4_HUMAN
NC score	0.101761 (rank : 70)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	138	Target Neighborhood Hits	136	Shared Neighborhood Hits	48
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNG2_HUMAN
NC score	0.101760 (rank : 71)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	138	Target Neighborhood Hits	83	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA3_HUMAN
NC score	0.101715 (rank : 72)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	43
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNQ1_MOUSE
NC score	0.100409 (rank : 73)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	138	Target Neighborhood Hits	175	Shared Neighborhood Hits	46
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNG4_HUMAN
NC score	0.099408 (rank : 74)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	36
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA3_MOUSE
NC score	0.099172 (rank : 75)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	138	Target Neighborhood Hits	103	Shared Neighborhood Hits	41
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

PKDRE_HUMAN
NC score	0.098614 (rank : 76)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNA5_HUMAN
NC score	0.097583 (rank : 77)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	138	Target Neighborhood Hits	124	Shared Neighborhood Hits	42
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ5_HUMAN
NC score	0.090878 (rank : 78)	θ value	0.0113563 (rank : 48)
Query Neighborhood Hits	138	Target Neighborhood Hits	163	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ1_HUMAN
NC score	0.089468 (rank : 79)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA4_MOUSE
NC score	0.088394 (rank : 80)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	138	Target Neighborhood Hits	98	Shared Neighborhood Hits	37
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.088067 (rank : 81)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	138	Target Neighborhood Hits	108	Shared Neighborhood Hits	37
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ3_HUMAN
NC score	0.076790 (rank : 82)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	42
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.076013 (rank : 83)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	138	Target Neighborhood Hits	105	Shared Neighborhood Hits	42
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_HUMAN
NC score	0.074944 (rank : 84)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	138	Target Neighborhood Hits	114	Shared Neighborhood Hits	39
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.072092 (rank : 85)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	138	Target Neighborhood Hits	163	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

PKDRE_MOUSE
NC score	0.069511 (rank : 86)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	138	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

MCLN2_MOUSE
NC score	0.062362 (rank : 87)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	138	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

TRPV3_HUMAN
NC score	0.062206 (rank : 88)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	138	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

KCMA1_MOUSE
NC score	0.050842 (rank : 89)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	138	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.050725 (rank : 90)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	138	Target Neighborhood Hits	96	Shared Neighborhood Hits	36
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

S36A1_MOUSE
NC score	0.033148 (rank : 91)	θ value	2.36792 (rank : 88)
Query Neighborhood Hits	138	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

IWS1_MOUSE
NC score	0.030924 (rank : 92)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	138	Target Neighborhood Hits	1258	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BSN_MOUSE
NC score	0.030250 (rank : 93)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	138	Target Neighborhood Hits	2057	Shared Neighborhood Hits	45
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

BAT3_HUMAN
NC score	0.028897 (rank : 94)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	138	Target Neighborhood Hits	490	Shared Neighborhood Hits	23
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

BAT3_MOUSE
NC score	0.028288 (rank : 95)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	138	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1R2, Q8SNA3	Gene names	Bat3
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3).

AFF1_HUMAN
NC score	0.027018 (rank : 96)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	138	Target Neighborhood Hits	506	Shared Neighborhood Hits	19
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

DIDO1_HUMAN
NC score	0.024115 (rank : 97)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	138	Target Neighborhood Hits	960	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PCLO_HUMAN
NC score	0.023389 (rank : 98)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	138	Target Neighborhood Hits	2046	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

TRPM2_MOUSE
NC score	0.021989 (rank : 99)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	138	Target Neighborhood Hits	61	Shared Neighborhood Hits	9
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

ATX1_MOUSE
NC score	0.021244 (rank : 100)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	138	Target Neighborhood Hits	264	Shared Neighborhood Hits	10
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

K0040_HUMAN
NC score	0.019615 (rank : 101)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	138	Target Neighborhood Hits	2	Shared Neighborhood Hits	2
SwissProt Accessions	Q15053	Gene names	KIAA0040
Domain Architecture	No domain graphic available
Description	Protein KIAA0040.

T240L_HUMAN
NC score	0.019025 (rank : 102)	θ value	3.0926 (rank : 97)
Query Neighborhood Hits	138	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

ATX1_HUMAN
NC score	0.018473 (rank : 103)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	138	Target Neighborhood Hits	79	Shared Neighborhood Hits	8
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

OGFR_HUMAN
NC score	0.018245 (rank : 104)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	138	Target Neighborhood Hits	1582	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NCOA6_MOUSE
NC score	0.017967 (rank : 105)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	138	Target Neighborhood Hits	1076	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.017574 (rank : 106)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	138	Target Neighborhood Hits	1202	Shared Neighborhood Hits	27
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

CGRE1_HUMAN
NC score	0.017429 (rank : 107)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	138	Target Neighborhood Hits	354	Shared Neighborhood Hits	13
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

TRPM2_HUMAN
NC score	0.015917 (rank : 108)	θ value	2.36792 (rank : 90)
Query Neighborhood Hits	138	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

HPS4_MOUSE
NC score	0.014951 (rank : 109)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	138	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q99KG7	Gene names	Hps4, Le
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein homolog (Light-ear protein) (Le protein).

ACE2_MOUSE
NC score	0.014894 (rank : 110)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	138	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R0I0, Q99N70, Q99N71	Gene names	Ace2
Domain Architecture	No domain graphic available
Description	Angiotensin-converting enzyme 2 precursor (EC 3.4.17.-) (ACE-related carboxypeptidase).

AMPH_MOUSE
NC score	0.014663 (rank : 111)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	138	Target Neighborhood Hits	291	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQF7, Q8R1C4	Gene names	Amph, Amph1
Domain Architecture
Description	Amphiphysin.

MLL3_MOUSE
NC score	0.013473 (rank : 112)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	138	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

ZN750_MOUSE
NC score	0.013065 (rank : 113)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	138	Target Neighborhood Hits	346	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

TAF2_HUMAN
NC score	0.012647 (rank : 114)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	138	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P1X5, O43487, O43604, O60668, Q86WW7, Q8IWK4	Gene names	TAF2, CIF150, TAF2B
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) (TBP-associated factor 150 kDa) (TAFII-150) (TAFII150) (150 kDa cofactor of initiator function).

LEUK_HUMAN
NC score	0.012544 (rank : 115)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	138	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P16150	Gene names	SPN, CD43
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Galactoglycoprotein) (GALGP) (CD43 antigen).

TGON1_MOUSE
NC score	0.011822 (rank : 116)	θ value	2.36792 (rank : 89)
Query Neighborhood Hits	138	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

ZN409_HUMAN
NC score	0.011620 (rank : 117)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	138	Target Neighborhood Hits	842	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

K1383_HUMAN
NC score	0.011158 (rank : 118)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	138	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2G4, Q58EZ9, Q5VV83	Gene names	KIAA1383
Domain Architecture	No domain graphic available
Description	Protein KIAA1383.

FYV1_HUMAN
NC score	0.010852 (rank : 119)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	138	Target Neighborhood Hits	217	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

RPTN_MOUSE
NC score	0.010395 (rank : 120)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	138	Target Neighborhood Hits	650	Shared Neighborhood Hits	17
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

EPN2_HUMAN
NC score	0.009808 (rank : 121)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	138	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

ZN598_HUMAN
NC score	0.009300 (rank : 122)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	138	Target Neighborhood Hits	339	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UK7, Q8IW49, Q8N3D9, Q96FG3, Q9H7J3	Gene names	ZNF598
Domain Architecture	No domain graphic available
Description	Zinc finger protein 598.

ZIMP7_MOUSE
NC score	0.009290 (rank : 123)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	138	Target Neighborhood Hits	566	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

FYV1_MOUSE
NC score	0.009119 (rank : 124)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	138	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

HES1_MOUSE
NC score	0.009084 (rank : 125)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	138	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

DCJ14_HUMAN
NC score	0.008834 (rank : 126)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	138	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q6Y2X3, Q66K17, Q96N59, Q96T63	Gene names	DNAJC14, DRIP78
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 14 (Dopamine receptor-interacting protein of 78 kDa) (DRiP78).

RECQ5_HUMAN
NC score	0.008107 (rank : 127)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	138	Target Neighborhood Hits	390	Shared Neighborhood Hits	16
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

TDRD6_MOUSE
NC score	0.007636 (rank : 128)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	138	Target Neighborhood Hits	82	Shared Neighborhood Hits	4
SwissProt Accessions	P61407	Gene names	Tdrd6
Domain Architecture
Description	Tudor domain-containing protein 6.

BCOR_MOUSE
NC score	0.007237 (rank : 129)	θ value	1.81305 (rank : 74)
Query Neighborhood Hits	138	Target Neighborhood Hits	521	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

GON4L_MOUSE
NC score	0.006204 (rank : 130)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	138	Target Neighborhood Hits	455	Shared Neighborhood Hits	15
SwissProt Accessions	Q9DB00, Q80TB4, Q91YI9	Gene names	Gon4l, Gon4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

FHR1_HUMAN
NC score	0.005607 (rank : 131)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	138	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

ANKR9_HUMAN
NC score	0.005387 (rank : 132)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	138	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

RELN_HUMAN
NC score	0.004802 (rank : 133)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	138	Target Neighborhood Hits	233	Shared Neighborhood Hits	5
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

FOG1_MOUSE
NC score	0.004200 (rank : 134)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	138	Target Neighborhood Hits	1237	Shared Neighborhood Hits	31
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

CFAH_HUMAN
NC score	0.004156 (rank : 135)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	138	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

HDAC4_HUMAN
NC score	0.004010 (rank : 136)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	138	Target Neighborhood Hits	390	Shared Neighborhood Hits	7
SwissProt Accessions	P56524, Q9UND6	Gene names	HDAC4, KIAA0288
Domain Architecture
Description	Histone deacetylase 4 (HD4).

RHG25_MOUSE
NC score	0.003996 (rank : 137)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	138	Target Neighborhood Hits	492	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

BIRC6_HUMAN
NC score	0.003399 (rank : 138)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	138	Target Neighborhood Hits	161	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NR09, Q9ULD1	Gene names	BIRC6, KIAA1289
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 6 (Ubiquitin-conjugating BIR-domain enzyme apollon).

BAZ2A_HUMAN
NC score	0.003379 (rank : 139)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	138	Target Neighborhood Hits	780	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

LPP_HUMAN
NC score	0.002321 (rank : 140)	θ value	3.0926 (rank : 96)
Query Neighborhood Hits	138	Target Neighborhood Hits	775	Shared Neighborhood Hits	14
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PPE2_HUMAN
NC score	0.002224 (rank : 141)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	138	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O14830, O14831	Gene names	PPEF2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

RIMB1_HUMAN
NC score	0.001863 (rank : 142)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	138	Target Neighborhood Hits	1479	Shared Neighborhood Hits	22
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ADA12_MOUSE
NC score	0.001802 (rank : 143)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	138	Target Neighborhood Hits	474	Shared Neighborhood Hits	12
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

TTBK1_HUMAN
NC score	0.001525 (rank : 144)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	138	Target Neighborhood Hits	1058	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

CO5A3_HUMAN
NC score	0.001413 (rank : 145)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	138	Target Neighborhood Hits	433	Shared Neighborhood Hits	14
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

LUZP1_MOUSE
NC score	0.001367 (rank : 146)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	138	Target Neighborhood Hits	940	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MEGF6_HUMAN
NC score	0.000924 (rank : 147)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	138	Target Neighborhood Hits	671	Shared Neighborhood Hits	5
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

LGR4_HUMAN
NC score	0.000618 (rank : 148)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	138	Target Neighborhood Hits	481	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXB1, Q9NYD1	Gene names	LGR4, GPR48
Domain Architecture
Description	Leucine-rich repeat-containing G-protein coupled receptor 4 precursor (G-protein coupled receptor 48).

STRN4_HUMAN
NC score	0.000299 (rank : 149)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	138	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NRL3	Gene names	STRN4, ZIN
Domain Architecture
Description	Striatin-4 (Zinedin).

CSPG3_MOUSE
NC score	0.000292 (rank : 150)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	138	Target Neighborhood Hits	657	Shared Neighborhood Hits	14
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

EP15_HUMAN
NC score	-0.001761 (rank : 151)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	138	Target Neighborhood Hits	1021	Shared Neighborhood Hits	7
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CALD1_HUMAN
NC score	-0.002184 (rank : 152)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	138	Target Neighborhood Hits	959	Shared Neighborhood Hits	8
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

ACM3_MOUSE
NC score	-0.003274 (rank : 153)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	138	Target Neighborhood Hits	932	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERZ3, Q64055	Gene names	Chrm3, Chrm-3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3 (Mm3 mAChR).

ZN597_HUMAN
NC score	-0.004863 (rank : 154)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	138	Target Neighborhood Hits	722	Shared Neighborhood Hits	5
SwissProt Accessions	Q96LX8	Gene names	ZNF597
Domain Architecture	No domain graphic available
Description	Zinc finger protein 597.

ZN509_MOUSE
NC score	-0.005136 (rank : 155)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	138	Target Neighborhood Hits	990	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

MARK2_HUMAN
NC score	-0.005271 (rank : 156)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	138	Target Neighborhood Hits	1056	Shared Neighborhood Hits	10
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).