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Network neighborhood for query Sequence : CAC1H_HUMAN

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CAC1H_HUMAN
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1G_HUMAN
θ value	0 (rank : 1)	NC score	0.951156 (rank : 4)
Query Neighborhood Hits	307	Target Neighborhood Hits	587	Shared Neighborhood Hits	127
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	307	Target Neighborhood Hits	307	Shared Neighborhood Hits	307
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
θ value	0 (rank : 3)	NC score	0.984657 (rank : 2)
Query Neighborhood Hits	307	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
θ value	0 (rank : 4)	NC score	0.977156 (rank : 3)
Query Neighborhood Hits	307	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_HUMAN
θ value	1.00358e-83 (rank : 5)	NC score	0.885626 (rank : 5)
Query Neighborhood Hits	307	Target Neighborhood Hits	111	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	1.11217e-74 (rank : 6)	NC score	0.884099 (rank : 6)
Query Neighborhood Hits	307	Target Neighborhood Hits	116	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1D_HUMAN
θ value	1.35953e-72 (rank : 7)	NC score	0.872910 (rank : 12)
Query Neighborhood Hits	307	Target Neighborhood Hits	118	Shared Neighborhood Hits	66
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

SCN4A_HUMAN
θ value	1.7756e-72 (rank : 8)	NC score	0.877043 (rank : 9)
Query Neighborhood Hits	307	Target Neighborhood Hits	133	Shared Neighborhood Hits	71
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN3A_HUMAN
θ value	2.31901e-72 (rank : 9)	NC score	0.870292 (rank : 15)
Query Neighborhood Hits	307	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN2A_HUMAN
θ value	3.95564e-72 (rank : 10)	NC score	0.866209 (rank : 22)
Query Neighborhood Hits	307	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

CAC1S_MOUSE
θ value	8.81223e-72 (rank : 11)	NC score	0.873680 (rank : 10)
Query Neighborhood Hits	307	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN9A_HUMAN
θ value	1.66191e-70 (rank : 12)	NC score	0.866034 (rank : 23)
Query Neighborhood Hits	307	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN1A_HUMAN
θ value	3.13423e-69 (rank : 13)	NC score	0.865624 (rank : 25)
Query Neighborhood Hits	307	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1E_HUMAN
θ value	3.4653e-68 (rank : 14)	NC score	0.877341 (rank : 8)
Query Neighborhood Hits	307	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	5.91091e-68 (rank : 15)	NC score	0.877552 (rank : 7)
Query Neighborhood Hits	307	Target Neighborhood Hits	167	Shared Neighborhood Hits	64
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1S_HUMAN
θ value	5.91091e-68 (rank : 16)	NC score	0.872252 (rank : 14)
Query Neighborhood Hits	307	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_MOUSE
θ value	3.83135e-67 (rank : 17)	NC score	0.867457 (rank : 20)
Query Neighborhood Hits	307	Target Neighborhood Hits	351	Shared Neighborhood Hits	93
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_MOUSE
θ value	1.6097e-65 (rank : 18)	NC score	0.865666 (rank : 24)
Query Neighborhood Hits	307	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1F_HUMAN
θ value	3.58603e-65 (rank : 19)	NC score	0.867686 (rank : 19)
Query Neighborhood Hits	307	Target Neighborhood Hits	141	Shared Neighborhood Hits	72
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SCN5A_HUMAN
θ value	5.17823e-64 (rank : 20)	NC score	0.873663 (rank : 11)
Query Neighborhood Hits	307	Target Neighborhood Hits	145	Shared Neighborhood Hits	67
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN8A_HUMAN
θ value	6.76295e-64 (rank : 21)	NC score	0.864236 (rank : 27)
Query Neighborhood Hits	307	Target Neighborhood Hits	135	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1F_MOUSE
θ value	1.15359e-63 (rank : 22)	NC score	0.867251 (rank : 21)
Query Neighborhood Hits	307	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1A_HUMAN
θ value	1.96772e-63 (rank : 23)	NC score	0.869069 (rank : 17)
Query Neighborhood Hits	307	Target Neighborhood Hits	387	Shared Neighborhood Hits	118
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SCN8A_MOUSE
θ value	2.56992e-63 (rank : 24)	NC score	0.861997 (rank : 29)
Query Neighborhood Hits	307	Target Neighborhood Hits	136	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1B_HUMAN
θ value	3.35642e-63 (rank : 25)	NC score	0.868752 (rank : 18)
Query Neighborhood Hits	307	Target Neighborhood Hits	257	Shared Neighborhood Hits	75
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_MOUSE
θ value	2.17557e-62 (rank : 26)	NC score	0.872762 (rank : 13)
Query Neighborhood Hits	307	Target Neighborhood Hits	267	Shared Neighborhood Hits	93
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

SC10A_MOUSE
θ value	4.53632e-60 (rank : 27)	NC score	0.864951 (rank : 26)
Query Neighborhood Hits	307	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN7A_HUMAN
θ value	1.31987e-59 (rank : 28)	NC score	0.869295 (rank : 16)
Query Neighborhood Hits	307	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SC10A_HUMAN
θ value	1.11734e-58 (rank : 29)	NC score	0.863336 (rank : 28)
Query Neighborhood Hits	307	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CAC1C_HUMAN
θ value	1.90589e-58 (rank : 30)	NC score	0.859437 (rank : 30)
Query Neighborhood Hits	307	Target Neighborhood Hits	158	Shared Neighborhood Hits	64
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

NFH_MOUSE
θ value	4.0297e-08 (rank : 31)	NC score	0.042615 (rank : 119)
Query Neighborhood Hits	307	Target Neighborhood Hits	2247	Shared Neighborhood Hits	146
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

KCNB1_HUMAN
θ value	5.81887e-07 (rank : 32)	NC score	0.242121 (rank : 40)
Query Neighborhood Hits	307	Target Neighborhood Hits	169	Shared Neighborhood Hits	63
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	5.81887e-07 (rank : 33)	NC score	0.242045 (rank : 41)
Query Neighborhood Hits	307	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNS2_MOUSE
θ value	3.77169e-06 (rank : 34)	NC score	0.249810 (rank : 38)
Query Neighborhood Hits	307	Target Neighborhood Hits	130	Shared Neighborhood Hits	62
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNV2_HUMAN
θ value	6.43352e-06 (rank : 35)	NC score	0.267503 (rank : 33)
Query Neighborhood Hits	307	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNS2_HUMAN
θ value	8.40245e-06 (rank : 36)	NC score	0.245381 (rank : 39)
Query Neighborhood Hits	307	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB2_HUMAN
θ value	1.09739e-05 (rank : 37)	NC score	0.252145 (rank : 36)
Query Neighborhood Hits	307	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS1_MOUSE
θ value	3.19293e-05 (rank : 38)	NC score	0.182987 (rank : 50)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
θ value	9.29e-05 (rank : 39)	NC score	0.191240 (rank : 49)
Query Neighborhood Hits	307	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_HUMAN
θ value	0.000158464 (rank : 40)	NC score	0.193736 (rank : 48)
Query Neighborhood Hits	307	Target Neighborhood Hits	116	Shared Neighborhood Hits	60
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

CJ012_HUMAN
θ value	0.00102713 (rank : 41)	NC score	0.055301 (rank : 95)
Query Neighborhood Hits	307	Target Neighborhood Hits	467	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

KCNC1_MOUSE
θ value	0.00175202 (rank : 42)	NC score	0.179656 (rank : 52)
Query Neighborhood Hits	307	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
θ value	0.00228821 (rank : 43)	NC score	0.180980 (rank : 51)
Query Neighborhood Hits	307	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNS3_HUMAN
θ value	0.00390308 (rank : 44)	NC score	0.214671 (rank : 43)
Query Neighborhood Hits	307	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

TPTE_HUMAN
θ value	0.00390308 (rank : 45)	NC score	0.141254 (rank : 59)
Query Neighborhood Hits	307	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCND2_MOUSE
θ value	0.00509761 (rank : 46)	NC score	0.198167 (rank : 46)
Query Neighborhood Hits	307	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
θ value	0.00665767 (rank : 47)	NC score	0.197726 (rank : 47)
Query Neighborhood Hits	307	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

MARCS_HUMAN
θ value	0.00869519 (rank : 48)	NC score	0.081359 (rank : 81)
Query Neighborhood Hits	307	Target Neighborhood Hits	204	Shared Neighborhood Hits	36
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

KCNF1_HUMAN
θ value	0.0148317 (rank : 49)	NC score	0.262557 (rank : 34)
Query Neighborhood Hits	307	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

RGS3_HUMAN
θ value	0.0148317 (rank : 50)	NC score	0.035344 (rank : 139)
Query Neighborhood Hits	307	Target Neighborhood Hits	1375	Shared Neighborhood Hits	119
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

CO5A1_HUMAN
θ value	0.0193708 (rank : 51)	NC score	0.053186 (rank : 98)
Query Neighborhood Hits	307	Target Neighborhood Hits	434	Shared Neighborhood Hits	75
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

ENAH_MOUSE
θ value	0.0193708 (rank : 52)	NC score	0.042874 (rank : 118)
Query Neighborhood Hits	307	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

MUC1_HUMAN
θ value	0.0193708 (rank : 53)	NC score	0.044349 (rank : 116)
Query Neighborhood Hits	307	Target Neighborhood Hits	975	Shared Neighborhood Hits	105
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PCLO_MOUSE
θ value	0.0252991 (rank : 54)	NC score	0.041533 (rank : 124)
Query Neighborhood Hits	307	Target Neighborhood Hits	2275	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

T240L_HUMAN
θ value	0.0330416 (rank : 55)	NC score	0.029892 (rank : 158)
Query Neighborhood Hits	307	Target Neighborhood Hits	132	Shared Neighborhood Hits	16
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

GRIN2_HUMAN
θ value	0.0431538 (rank : 56)	NC score	0.041016 (rank : 127)
Query Neighborhood Hits	307	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

SNPC4_HUMAN
θ value	0.0431538 (rank : 57)	NC score	0.045008 (rank : 112)
Query Neighborhood Hits	307	Target Neighborhood Hits	589	Shared Neighborhood Hits	80
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

ES8L1_MOUSE
θ value	0.0563607 (rank : 58)	NC score	0.017186 (rank : 205)
Query Neighborhood Hits	307	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

CO5A1_MOUSE
θ value	0.0736092 (rank : 59)	NC score	0.051217 (rank : 100)
Query Neighborhood Hits	307	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CTDP1_HUMAN
θ value	0.0736092 (rank : 60)	NC score	0.044718 (rank : 114)
Query Neighborhood Hits	307	Target Neighborhood Hits	416	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

KCNC3_HUMAN
θ value	0.0736092 (rank : 61)	NC score	0.155404 (rank : 56)
Query Neighborhood Hits	307	Target Neighborhood Hits	256	Shared Neighborhood Hits	81
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_HUMAN
θ value	0.0736092 (rank : 62)	NC score	0.165021 (rank : 55)
Query Neighborhood Hits	307	Target Neighborhood Hits	141	Shared Neighborhood Hits	58
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

AATK_MOUSE
θ value	0.0961366 (rank : 63)	NC score	0.007201 (rank : 263)
Query Neighborhood Hits	307	Target Neighborhood Hits	942	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

PK2L1_HUMAN
θ value	0.0961366 (rank : 64)	NC score	0.274069 (rank : 32)
Query Neighborhood Hits	307	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

CXXC6_HUMAN
θ value	0.125558 (rank : 65)	NC score	0.031606 (rank : 153)
Query Neighborhood Hits	307	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

KCNC3_MOUSE
θ value	0.125558 (rank : 66)	NC score	0.151518 (rank : 58)
Query Neighborhood Hits	307	Target Neighborhood Hits	173	Shared Neighborhood Hits	59
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

RREB1_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.005883 (rank : 272)
Query Neighborhood Hits	307	Target Neighborhood Hits	879	Shared Neighborhood Hits	41
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

CCD45_MOUSE
θ value	0.163984 (rank : 68)	NC score	0.017688 (rank : 202)
Query Neighborhood Hits	307	Target Neighborhood Hits	663	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CO1A1_MOUSE
θ value	0.163984 (rank : 69)	NC score	0.054347 (rank : 96)
Query Neighborhood Hits	307	Target Neighborhood Hits	457	Shared Neighborhood Hits	88
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

HIC1_HUMAN
θ value	0.163984 (rank : 70)	NC score	0.001057 (rank : 305)
Query Neighborhood Hits	307	Target Neighborhood Hits	838	Shared Neighborhood Hits	30
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

RPGR1_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.015381 (rank : 216)
Query Neighborhood Hits	307	Target Neighborhood Hits	578	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

AF10_MOUSE
θ value	0.21417 (rank : 72)	NC score	0.017538 (rank : 203)
Query Neighborhood Hits	307	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

CO1A2_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.044599 (rank : 115)
Query Neighborhood Hits	307	Target Neighborhood Hits	329	Shared Neighborhood Hits	66
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

GA2L1_MOUSE
θ value	0.21417 (rank : 74)	NC score	0.030559 (rank : 156)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

M3K15_HUMAN
θ value	0.21417 (rank : 75)	NC score	0.001273 (rank : 303)
Query Neighborhood Hits	307	Target Neighborhood Hits	914	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

NCA11_MOUSE
θ value	0.21417 (rank : 76)	NC score	0.013224 (rank : 229)
Query Neighborhood Hits	307	Target Neighborhood Hits	661	Shared Neighborhood Hits	40
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PK2L2_HUMAN
θ value	0.21417 (rank : 77)	NC score	0.289441 (rank : 31)
Query Neighborhood Hits	307	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TIF1B_HUMAN
θ value	0.21417 (rank : 78)	NC score	0.014499 (rank : 221)
Query Neighborhood Hits	307	Target Neighborhood Hits	312	Shared Neighborhood Hits	21
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

UBP43_HUMAN
θ value	0.21417 (rank : 79)	NC score	0.012984 (rank : 230)
Query Neighborhood Hits	307	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

CO4A4_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.041397 (rank : 126)
Query Neighborhood Hits	307	Target Neighborhood Hits	440	Shared Neighborhood Hits	71
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

KCND3_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.199330 (rank : 45)
Query Neighborhood Hits	307	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.279714 (rank : 82)	NC score	0.199511 (rank : 44)
Query Neighborhood Hits	307	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

TITIN_HUMAN
θ value	0.279714 (rank : 83)	NC score	0.003804 (rank : 285)
Query Neighborhood Hits	307	Target Neighborhood Hits	2923	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BASP_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.059185 (rank : 90)
Query Neighborhood Hits	307	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CO7A1_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.033365 (rank : 144)
Query Neighborhood Hits	307	Target Neighborhood Hits	807	Shared Neighborhood Hits	85
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

EDN3_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.032739 (rank : 146)
Query Neighborhood Hits	307	Target Neighborhood Hits	61	Shared Neighborhood Hits	15
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

NCOR2_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.035391 (rank : 138)
Query Neighborhood Hits	307	Target Neighborhood Hits	870	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

PAX9_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.016360 (rank : 209)
Query Neighborhood Hits	307	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

CO1A1_HUMAN
θ value	0.47712 (rank : 89)	NC score	0.050132 (rank : 103)
Query Neighborhood Hits	307	Target Neighborhood Hits	475	Shared Neighborhood Hits	86
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

DJBP_HUMAN
θ value	0.47712 (rank : 90)	NC score	0.019571 (rank : 191)
Query Neighborhood Hits	307	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

MLL3_MOUSE
θ value	0.47712 (rank : 91)	NC score	0.026343 (rank : 173)
Query Neighborhood Hits	307	Target Neighborhood Hits	1399	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PCLO_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.047866 (rank : 109)
Query Neighborhood Hits	307	Target Neighborhood Hits	2046	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

RGS3_MOUSE
θ value	0.47712 (rank : 93)	NC score	0.044978 (rank : 113)
Query Neighborhood Hits	307	Target Neighborhood Hits	1621	Shared Neighborhood Hits	140
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZFY16_HUMAN
θ value	0.47712 (rank : 94)	NC score	0.012086 (rank : 236)
Query Neighborhood Hits	307	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

BASP_HUMAN
θ value	0.62314 (rank : 95)	NC score	0.048531 (rank : 107)
Query Neighborhood Hits	307	Target Neighborhood Hits	321	Shared Neighborhood Hits	45
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

FA8A1_HUMAN
θ value	0.62314 (rank : 96)	NC score	0.032122 (rank : 149)
Query Neighborhood Hits	307	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

GP124_MOUSE
θ value	0.62314 (rank : 97)	NC score	0.006453 (rank : 270)
Query Neighborhood Hits	307	Target Neighborhood Hits	423	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

HCN4_MOUSE
θ value	0.62314 (rank : 98)	NC score	0.025642 (rank : 176)
Query Neighborhood Hits	307	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

CEP72_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.017910 (rank : 198)
Query Neighborhood Hits	307	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

DCE2_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.010262 (rank : 247)
Query Neighborhood Hits	307	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

LAP4_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.007229 (rank : 262)
Query Neighborhood Hits	307	Target Neighborhood Hits	608	Shared Neighborhood Hits	33
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MARCS_MOUSE
θ value	0.813845 (rank : 102)	NC score	0.049607 (rank : 105)
Query Neighborhood Hits	307	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

MBB1A_HUMAN
θ value	0.813845 (rank : 103)	NC score	0.033821 (rank : 143)
Query Neighborhood Hits	307	Target Neighborhood Hits	665	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MILK2_HUMAN
θ value	0.813845 (rank : 104)	NC score	0.019057 (rank : 192)
Query Neighborhood Hits	307	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NHERF_MOUSE
θ value	0.813845 (rank : 105)	NC score	0.011793 (rank : 237)
Query Neighborhood Hits	307	Target Neighborhood Hits	195	Shared Neighborhood Hits	13
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

PKD2_MOUSE
θ value	0.813845 (rank : 106)	NC score	0.251857 (rank : 37)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

S36A1_MOUSE
θ value	0.813845 (rank : 107)	NC score	0.037865 (rank : 134)
Query Neighborhood Hits	307	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

SREC2_MOUSE
θ value	0.813845 (rank : 108)	NC score	0.011576 (rank : 239)
Query Neighborhood Hits	307	Target Neighborhood Hits	605	Shared Neighborhood Hits	33
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CF057_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.027279 (rank : 169)
Query Neighborhood Hits	307	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VUM1	Gene names	C6orf57
Domain Architecture	No domain graphic available
Description	UPF0369 protein C6orf57 precursor.

CO002_HUMAN
θ value	1.06291 (rank : 110)	NC score	0.038293 (rank : 132)
Query Neighborhood Hits	307	Target Neighborhood Hits	387	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

COBA2_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.042396 (rank : 121)
Query Neighborhood Hits	307	Target Neighborhood Hits	408	Shared Neighborhood Hits	72
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

MAGE1_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.032268 (rank : 148)
Query Neighborhood Hits	307	Target Neighborhood Hits	1389	Shared Neighborhood Hits	127
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TAU_HUMAN
θ value	1.06291 (rank : 113)	NC score	0.050812 (rank : 101)
Query Neighborhood Hits	307	Target Neighborhood Hits	448	Shared Neighborhood Hits	81
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TNC6B_HUMAN
θ value	1.06291 (rank : 114)	NC score	0.030760 (rank : 155)
Query Neighborhood Hits	307	Target Neighborhood Hits	256	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

WASIP_HUMAN
θ value	1.06291 (rank : 115)	NC score	0.053247 (rank : 97)
Query Neighborhood Hits	307	Target Neighborhood Hits	458	Shared Neighborhood Hits	57
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

ZC3H5_HUMAN
θ value	1.06291 (rank : 116)	NC score	0.017906 (rank : 199)
Query Neighborhood Hits	307	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

5HT6R_HUMAN
θ value	1.38821 (rank : 117)	NC score	-0.000873 (rank : 317)
Query Neighborhood Hits	307	Target Neighborhood Hits	882	Shared Neighborhood Hits	4
SwissProt Accessions	P50406, Q13640	Gene names	HTR6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

5HT6R_MOUSE
θ value	1.38821 (rank : 118)	NC score	-0.000807 (rank : 316)
Query Neighborhood Hits	307	Target Neighborhood Hits	881	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1C8	Gene names	Htr6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

CO6A1_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.028128 (rank : 164)
Query Neighborhood Hits	307	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

MAST2_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.001131 (rank : 304)
Query Neighborhood Hits	307	Target Neighborhood Hits	1110	Shared Neighborhood Hits	46
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PK1L1_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.035642 (rank : 137)
Query Neighborhood Hits	307	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

SIPA1_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.015979 (rank : 210)
Query Neighborhood Hits	307	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
θ value	1.38821 (rank : 123)	NC score	0.015649 (rank : 211)
Query Neighborhood Hits	307	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

TAF4_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.048945 (rank : 106)
Query Neighborhood Hits	307	Target Neighborhood Hits	687	Shared Neighborhood Hits	70
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TAF5_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.001613 (rank : 300)
Query Neighborhood Hits	307	Target Neighborhood Hits	352	Shared Neighborhood Hits	8
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TRPV3_HUMAN
θ value	1.38821 (rank : 126)	NC score	0.062571 (rank : 87)
Query Neighborhood Hits	307	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

UBE4B_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.021211 (rank : 185)
Query Neighborhood Hits	307	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ZBT10_HUMAN
θ value	1.38821 (rank : 128)	NC score	-0.001078 (rank : 319)
Query Neighborhood Hits	307	Target Neighborhood Hits	831	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

COBA1_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.042225 (rank : 123)
Query Neighborhood Hits	307	Target Neighborhood Hits	491	Shared Neighborhood Hits	78
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA2_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.040758 (rank : 129)
Query Neighborhood Hits	307	Target Neighborhood Hits	501	Shared Neighborhood Hits	76
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CSKI1_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.012545 (rank : 232)
Query Neighborhood Hits	307	Target Neighborhood Hits	997	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DVL2_MOUSE
θ value	1.81305 (rank : 132)	NC score	0.010958 (rank : 241)
Query Neighborhood Hits	307	Target Neighborhood Hits	233	Shared Neighborhood Hits	24
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

GTSE1_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.029892 (rank : 157)
Query Neighborhood Hits	307	Target Neighborhood Hits	193	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

HCN2_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.020863 (rank : 188)
Query Neighborhood Hits	307	Target Neighborhood Hits	369	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

KCND1_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.176158 (rank : 53)
Query Neighborhood Hits	307	Target Neighborhood Hits	160	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

LDB3_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.012323 (rank : 234)
Query Neighborhood Hits	307	Target Neighborhood Hits	497	Shared Neighborhood Hits	39
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LIPA3_MOUSE
θ value	1.81305 (rank : 137)	NC score	0.004771 (rank : 278)
Query Neighborhood Hits	307	Target Neighborhood Hits	636	Shared Neighborhood Hits	18
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LRC41_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.014972 (rank : 219)
Query Neighborhood Hits	307	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

MAST1_MOUSE
θ value	1.81305 (rank : 139)	NC score	0.002750 (rank : 294)
Query Neighborhood Hits	307	Target Neighborhood Hits	1123	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MLL3_HUMAN
θ value	1.81305 (rank : 140)	NC score	0.022455 (rank : 182)
Query Neighborhood Hits	307	Target Neighborhood Hits	1644	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PKDRE_HUMAN
θ value	1.81305 (rank : 141)	NC score	0.090949 (rank : 77)
Query Neighborhood Hits	307	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PRDM8_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.008208 (rank : 257)
Query Neighborhood Hits	307	Target Neighborhood Hits	591	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NQV8, Q6IQ36	Gene names	PRDM8, PFM5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

SIA7A_MOUSE
θ value	1.81305 (rank : 143)	NC score	0.012815 (rank : 231)
Query Neighborhood Hits	307	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

TCGAP_HUMAN
θ value	1.81305 (rank : 144)	NC score	0.023788 (rank : 179)
Query Neighborhood Hits	307	Target Neighborhood Hits	872	Shared Neighborhood Hits	81
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TOIP2_MOUSE
θ value	1.81305 (rank : 145)	NC score	0.026737 (rank : 171)
Query Neighborhood Hits	307	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

ZIC2_MOUSE
θ value	1.81305 (rank : 146)	NC score	-0.002619 (rank : 323)
Query Neighborhood Hits	307	Target Neighborhood Hits	727	Shared Neighborhood Hits	15
SwissProt Accessions	Q62520	Gene names	Zic2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2).

BSN_MOUSE
θ value	2.36792 (rank : 147)	NC score	0.062018 (rank : 88)
Query Neighborhood Hits	307	Target Neighborhood Hits	2057	Shared Neighborhood Hits	169
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO039_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.034607 (rank : 141)
Query Neighborhood Hits	307	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CO2A1_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.046426 (rank : 110)
Query Neighborhood Hits	307	Target Neighborhood Hits	486	Shared Neighborhood Hits	80
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO5A2_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.040776 (rank : 128)
Query Neighborhood Hits	307	Target Neighborhood Hits	760	Shared Neighborhood Hits	96
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

GOGA3_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.000210 (rank : 310)
Query Neighborhood Hits	307	Target Neighborhood Hits	1317	Shared Neighborhood Hits	35
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GP179_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.036443 (rank : 136)
Query Neighborhood Hits	307	Target Neighborhood Hits	372	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

HCN4_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.028504 (rank : 163)
Query Neighborhood Hits	307	Target Neighborhood Hits	303	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HME2_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.000912 (rank : 306)
Query Neighborhood Hits	307	Target Neighborhood Hits	355	Shared Neighborhood Hits	9
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

JIP4_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.009318 (rank : 252)
Query Neighborhood Hits	307	Target Neighborhood Hits	585	Shared Neighborhood Hits	23
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

KCNA1_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.115828 (rank : 62)
Query Neighborhood Hits	307	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNG3_MOUSE
θ value	2.36792 (rank : 157)	NC score	0.135507 (rank : 61)
Query Neighborhood Hits	307	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNQ1_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.086902 (rank : 80)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

LAT3_MOUSE
θ value	2.36792 (rank : 159)	NC score	0.013388 (rank : 226)
Query Neighborhood Hits	307	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSM7, Q9D0H7	Gene names	Slc43a1, Lat3
Domain Architecture	No domain graphic available
Description	Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Solute carrier family 43 member 1).

MAP1B_HUMAN
θ value	2.36792 (rank : 160)	NC score	0.018648 (rank : 193)
Query Neighborhood Hits	307	Target Neighborhood Hits	903	Shared Neighborhood Hits	44
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MARK4_MOUSE
θ value	2.36792 (rank : 161)	NC score	-0.000945 (rank : 318)
Query Neighborhood Hits	307	Target Neighborhood Hits	898	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

MCLN2_MOUSE
θ value	2.36792 (rank : 162)	NC score	0.055333 (rank : 94)
Query Neighborhood Hits	307	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

MYCB_MOUSE
θ value	2.36792 (rank : 163)	NC score	0.014025 (rank : 223)
Query Neighborhood Hits	307	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

PK2L2_MOUSE
θ value	2.36792 (rank : 164)	NC score	0.256400 (rank : 35)
Query Neighborhood Hits	307	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

RP3A_HUMAN
θ value	2.36792 (rank : 165)	NC score	0.015533 (rank : 214)
Query Neighborhood Hits	307	Target Neighborhood Hits	305	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SRRM1_MOUSE
θ value	2.36792 (rank : 166)	NC score	0.057974 (rank : 93)
Query Neighborhood Hits	307	Target Neighborhood Hits	966	Shared Neighborhood Hits	93
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

ZNF71_HUMAN
θ value	2.36792 (rank : 167)	NC score	-0.004339 (rank : 326)
Query Neighborhood Hits	307	Target Neighborhood Hits	764	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQZ8, Q15919, Q9UC09, Q9UQD3	Gene names	ZNF71, EZFIT
Domain Architecture
Description	Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71) (ZNF47).

AATK_HUMAN
θ value	3.0926 (rank : 168)	NC score	0.007897 (rank : 259)
Query Neighborhood Hits	307	Target Neighborhood Hits	1243	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

BAT4_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.009858 (rank : 248)
Query Neighborhood Hits	307	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CGRE1_HUMAN
θ value	3.0926 (rank : 170)	NC score	0.039640 (rank : 130)
Query Neighborhood Hits	307	Target Neighborhood Hits	354	Shared Neighborhood Hits	57
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

CIZ1_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.020407 (rank : 189)
Query Neighborhood Hits	307	Target Neighborhood Hits	359	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

CO8A2_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.032774 (rank : 145)
Query Neighborhood Hits	307	Target Neighborhood Hits	299	Shared Neighborhood Hits	54
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

COBA1_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.042605 (rank : 120)
Query Neighborhood Hits	307	Target Neighborhood Hits	487	Shared Neighborhood Hits	76
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

CUTL1_MOUSE
θ value	3.0926 (rank : 174)	NC score	0.005399 (rank : 274)
Query Neighborhood Hits	307	Target Neighborhood Hits	1620	Shared Neighborhood Hits	65
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DGKK_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.024857 (rank : 178)
Query Neighborhood Hits	307	Target Neighborhood Hits	378	Shared Neighborhood Hits	41
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

EPN3_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.016445 (rank : 208)
Query Neighborhood Hits	307	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

INVS_HUMAN
θ value	3.0926 (rank : 177)	NC score	0.004565 (rank : 280)
Query Neighborhood Hits	307	Target Neighborhood Hits	455	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

INVS_MOUSE
θ value	3.0926 (rank : 178)	NC score	0.008051 (rank : 258)
Query Neighborhood Hits	307	Target Neighborhood Hits	609	Shared Neighborhood Hits	44
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

KBTBB_HUMAN
θ value	3.0926 (rank : 179)	NC score	0.006677 (rank : 268)
Query Neighborhood Hits	307	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

KCNC4_MOUSE
θ value	3.0926 (rank : 180)	NC score	0.153224 (rank : 57)
Query Neighborhood Hits	307	Target Neighborhood Hits	130	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNQ1_MOUSE
θ value	3.0926 (rank : 181)	NC score	0.097057 (rank : 74)
Query Neighborhood Hits	307	Target Neighborhood Hits	175	Shared Neighborhood Hits	53
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

MAP1B_MOUSE
θ value	3.0926 (rank : 182)	NC score	0.017775 (rank : 201)
Query Neighborhood Hits	307	Target Neighborhood Hits	977	Shared Neighborhood Hits	45
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAST1_HUMAN
θ value	3.0926 (rank : 183)	NC score	0.002197 (rank : 299)
Query Neighborhood Hits	307	Target Neighborhood Hits	1146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

NDF6_MOUSE
θ value	3.0926 (rank : 184)	NC score	0.007171 (rank : 264)
Query Neighborhood Hits	307	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

NEST_HUMAN
θ value	3.0926 (rank : 185)	NC score	0.012374 (rank : 233)
Query Neighborhood Hits	307	Target Neighborhood Hits	1305	Shared Neighborhood Hits	78
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

PCSK7_MOUSE
θ value	3.0926 (rank : 186)	NC score	0.005101 (rank : 276)
Query Neighborhood Hits	307	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

PGCA_HUMAN
θ value	3.0926 (rank : 187)	NC score	0.022763 (rank : 180)
Query Neighborhood Hits	307	Target Neighborhood Hits	821	Shared Neighborhood Hits	72
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

RUSC2_MOUSE
θ value	3.0926 (rank : 188)	NC score	0.029313 (rank : 161)
Query Neighborhood Hits	307	Target Neighborhood Hits	305	Shared Neighborhood Hits	45
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SHAN2_MOUSE
θ value	3.0926 (rank : 189)	NC score	0.017775 (rank : 200)
Query Neighborhood Hits	307	Target Neighborhood Hits	446	Shared Neighborhood Hits	33
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SLC2B_HUMAN
θ value	3.0926 (rank : 190)	NC score	0.015084 (rank : 218)
Query Neighborhood Hits	307	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

TACC3_HUMAN
θ value	3.0926 (rank : 191)	NC score	0.013270 (rank : 227)
Query Neighborhood Hits	307	Target Neighborhood Hits	779	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TAU_MOUSE
θ value	3.0926 (rank : 192)	NC score	0.038463 (rank : 131)
Query Neighborhood Hits	307	Target Neighborhood Hits	502	Shared Neighborhood Hits	75
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CABIN_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.038140 (rank : 133)
Query Neighborhood Hits	307	Target Neighborhood Hits	490	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CO2A1_MOUSE
θ value	4.03905 (rank : 194)	NC score	0.043076 (rank : 117)
Query Neighborhood Hits	307	Target Neighborhood Hits	483	Shared Neighborhood Hits	73
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

COAA1_MOUSE
θ value	4.03905 (rank : 195)	NC score	0.032298 (rank : 147)
Query Neighborhood Hits	307	Target Neighborhood Hits	286	Shared Neighborhood Hits	49
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

DOT1L_HUMAN
θ value	4.03905 (rank : 196)	NC score	0.031762 (rank : 152)
Query Neighborhood Hits	307	Target Neighborhood Hits	660	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DSCL1_HUMAN
θ value	4.03905 (rank : 197)	NC score	0.004083 (rank : 283)
Query Neighborhood Hits	307	Target Neighborhood Hits	589	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

EGR1_HUMAN
θ value	4.03905 (rank : 198)	NC score	-0.002992 (rank : 325)
Query Neighborhood Hits	307	Target Neighborhood Hits	788	Shared Neighborhood Hits	21
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

GNAS1_HUMAN
θ value	4.03905 (rank : 199)	NC score	0.014548 (rank : 220)
Query Neighborhood Hits	307	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

IRAK1_HUMAN
θ value	4.03905 (rank : 200)	NC score	0.002583 (rank : 295)
Query Neighborhood Hits	307	Target Neighborhood Hits	820	Shared Neighborhood Hits	30
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	4.03905 (rank : 201)	NC score	-0.000095 (rank : 311)
Query Neighborhood Hits	307	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

KCNA1_HUMAN
θ value	4.03905 (rank : 202)	NC score	0.113463 (rank : 63)
Query Neighborhood Hits	307	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_HUMAN
θ value	4.03905 (rank : 203)	NC score	0.110069 (rank : 65)
Query Neighborhood Hits	307	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	4.03905 (rank : 204)	NC score	0.111427 (rank : 64)
Query Neighborhood Hits	307	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

M3K14_HUMAN
θ value	4.03905 (rank : 205)	NC score	-0.001229 (rank : 320)
Query Neighborhood Hits	307	Target Neighborhood Hits	887	Shared Neighborhood Hits	28
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

MILK1_MOUSE
θ value	4.03905 (rank : 206)	NC score	0.036458 (rank : 135)
Query Neighborhood Hits	307	Target Neighborhood Hits	788	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

PAR6G_HUMAN
θ value	4.03905 (rank : 207)	NC score	0.010471 (rank : 245)
Query Neighborhood Hits	307	Target Neighborhood Hits	159	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

PLCB3_HUMAN
θ value	4.03905 (rank : 208)	NC score	0.004315 (rank : 281)
Query Neighborhood Hits	307	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

PRRT3_HUMAN
θ value	4.03905 (rank : 209)	NC score	0.042385 (rank : 122)
Query Neighborhood Hits	307	Target Neighborhood Hits	998	Shared Neighborhood Hits	108
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PYGO2_HUMAN
θ value	4.03905 (rank : 210)	NC score	0.018272 (rank : 196)
Query Neighborhood Hits	307	Target Neighborhood Hits	189	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

SH24A_MOUSE
θ value	4.03905 (rank : 211)	NC score	0.010584 (rank : 243)
Query Neighborhood Hits	307	Target Neighborhood Hits	326	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

SYNPO_HUMAN
θ value	4.03905 (rank : 212)	NC score	0.020951 (rank : 187)
Query Neighborhood Hits	307	Target Neighborhood Hits	281	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

T2FA_HUMAN
θ value	4.03905 (rank : 213)	NC score	0.020131 (rank : 190)
Query Neighborhood Hits	307	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

TRPM2_MOUSE
θ value	4.03905 (rank : 214)	NC score	0.017143 (rank : 206)
Query Neighborhood Hits	307	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

AMPH_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.017325 (rank : 204)
Query Neighborhood Hits	307	Target Neighborhood Hits	455	Shared Neighborhood Hits	35
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ARSI_HUMAN
θ value	5.27518 (rank : 216)	NC score	0.004576 (rank : 279)
Query Neighborhood Hits	307	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

BAT2_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.048002 (rank : 108)
Query Neighborhood Hits	307	Target Neighborhood Hits	931	Shared Neighborhood Hits	100
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BFSP1_HUMAN
θ value	5.27518 (rank : 218)	NC score	0.003152 (rank : 291)
Query Neighborhood Hits	307	Target Neighborhood Hits	508	Shared Neighborhood Hits	13
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

CHSS3_HUMAN
θ value	5.27518 (rank : 219)	NC score	0.015375 (rank : 217)
Query Neighborhood Hits	307	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

CSPG3_HUMAN
θ value	5.27518 (rank : 220)	NC score	0.002479 (rank : 297)
Query Neighborhood Hits	307	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DOCK4_MOUSE
θ value	5.27518 (rank : 221)	NC score	0.009707 (rank : 250)
Query Neighborhood Hits	307	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

DVL2_HUMAN
θ value	5.27518 (rank : 222)	NC score	0.009771 (rank : 249)
Query Neighborhood Hits	307	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

EMIL1_MOUSE
θ value	5.27518 (rank : 223)	NC score	0.017131 (rank : 207)
Query Neighborhood Hits	307	Target Neighborhood Hits	214	Shared Neighborhood Hits	32
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

FGFR1_HUMAN
θ value	5.27518 (rank : 224)	NC score	-0.002577 (rank : 322)
Query Neighborhood Hits	307	Target Neighborhood Hits	1069	Shared Neighborhood Hits	22
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

GPTC8_HUMAN
θ value	5.27518 (rank : 225)	NC score	0.027032 (rank : 170)
Query Neighborhood Hits	307	Target Neighborhood Hits	366	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

IQEC2_MOUSE
θ value	5.27518 (rank : 226)	NC score	0.018521 (rank : 194)
Query Neighborhood Hits	307	Target Neighborhood Hits	417	Shared Neighborhood Hits	32
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

KCC2B_HUMAN
θ value	5.27518 (rank : 227)	NC score	-0.001336 (rank : 321)
Query Neighborhood Hits	307	Target Neighborhood Hits	866	Shared Neighborhood Hits	26
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

KCNG3_HUMAN
θ value	5.27518 (rank : 228)	NC score	0.136365 (rank : 60)
Query Neighborhood Hits	307	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

MAGD4_HUMAN
θ value	5.27518 (rank : 229)	NC score	0.009472 (rank : 251)
Query Neighborhood Hits	307	Target Neighborhood Hits	338	Shared Neighborhood Hits	44
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MTSS1_HUMAN
θ value	5.27518 (rank : 230)	NC score	0.021189 (rank : 186)
Query Neighborhood Hits	307	Target Neighborhood Hits	504	Shared Neighborhood Hits	59
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MYLK2_HUMAN
θ value	5.27518 (rank : 231)	NC score	0.000691 (rank : 307)
Query Neighborhood Hits	307	Target Neighborhood Hits	920	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

NDF6_HUMAN
θ value	5.27518 (rank : 232)	NC score	0.006166 (rank : 271)
Query Neighborhood Hits	307	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NU133_MOUSE
θ value	5.27518 (rank : 233)	NC score	0.007888 (rank : 260)
Query Neighborhood Hits	307	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

RPKL1_HUMAN
θ value	5.27518 (rank : 234)	NC score	-0.000148 (rank : 312)
Query Neighborhood Hits	307	Target Neighborhood Hits	708	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

SFTPD_MOUSE
θ value	5.27518 (rank : 235)	NC score	0.025965 (rank : 174)
Query Neighborhood Hits	307	Target Neighborhood Hits	217	Shared Neighborhood Hits	44
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

SPEG_HUMAN
θ value	5.27518 (rank : 236)	NC score	0.006960 (rank : 267)
Query Neighborhood Hits	307	Target Neighborhood Hits	1762	Shared Neighborhood Hits	102
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SREC2_HUMAN
θ value	5.27518 (rank : 237)	NC score	0.015548 (rank : 213)
Query Neighborhood Hits	307	Target Neighborhood Hits	645	Shared Neighborhood Hits	44
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

STIM2_HUMAN
θ value	5.27518 (rank : 238)	NC score	0.004983 (rank : 277)
Query Neighborhood Hits	307	Target Neighborhood Hits	420	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

TB182_HUMAN
θ value	5.27518 (rank : 239)	NC score	0.035122 (rank : 140)
Query Neighborhood Hits	307	Target Neighborhood Hits	414	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TXLNA_HUMAN
θ value	5.27518 (rank : 240)	NC score	0.009201 (rank : 253)
Query Neighborhood Hits	307	Target Neighborhood Hits	982	Shared Neighborhood Hits	63
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

ZFHX2_HUMAN
θ value	5.27518 (rank : 241)	NC score	0.006564 (rank : 269)
Query Neighborhood Hits	307	Target Neighborhood Hits	1178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

ZFY28_HUMAN
θ value	5.27518 (rank : 242)	NC score	0.009112 (rank : 255)
Query Neighborhood Hits	307	Target Neighborhood Hits	152	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

ZN497_HUMAN
θ value	5.27518 (rank : 243)	NC score	-0.004619 (rank : 327)
Query Neighborhood Hits	307	Target Neighborhood Hits	748	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZNH5, Q6ZTD2, Q9UIA8	Gene names	ZNF497
Domain Architecture	No domain graphic available
Description	Zinc finger protein 497.

ADA12_MOUSE
θ value	6.88961 (rank : 244)	NC score	0.003625 (rank : 287)
Query Neighborhood Hits	307	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ATBF1_HUMAN
θ value	6.88961 (rank : 245)	NC score	0.001403 (rank : 302)
Query Neighborhood Hits	307	Target Neighborhood Hits	1547	Shared Neighborhood Hits	60
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BAG3_MOUSE
θ value	6.88961 (rank : 246)	NC score	0.025570 (rank : 177)
Query Neighborhood Hits	307	Target Neighborhood Hits	513	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CLCN7_MOUSE
θ value	6.88961 (rank : 247)	NC score	0.003288 (rank : 290)
Query Neighborhood Hits	307	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	O70496	Gene names	Clcn7, Clc7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

CO3A1_HUMAN
θ value	6.88961 (rank : 248)	NC score	0.049726 (rank : 104)
Query Neighborhood Hits	307	Target Neighborhood Hits	452	Shared Neighborhood Hits	79
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO4A2_MOUSE
θ value	6.88961 (rank : 249)	NC score	0.031344 (rank : 154)
Query Neighborhood Hits	307	Target Neighborhood Hits	492	Shared Neighborhood Hits	69
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

COAA1_HUMAN
θ value	6.88961 (rank : 250)	NC score	0.032066 (rank : 150)
Query Neighborhood Hits	307	Target Neighborhood Hits	316	Shared Neighborhood Hits	58
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CS034_HUMAN
θ value	6.88961 (rank : 251)	NC score	0.015462 (rank : 215)
Query Neighborhood Hits	307	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NCQ2	Gene names	C19orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf34.

DUT_HUMAN
θ value	6.88961 (rank : 252)	NC score	0.021405 (rank : 184)
Query Neighborhood Hits	307	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

FGFR1_MOUSE
θ value	6.88961 (rank : 253)	NC score	-0.002671 (rank : 324)
Query Neighborhood Hits	307	Target Neighborhood Hits	1068	Shared Neighborhood Hits	22
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FOG1_HUMAN
θ value	6.88961 (rank : 254)	NC score	0.011666 (rank : 238)
Query Neighborhood Hits	307	Target Neighborhood Hits	981	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HXA2_HUMAN
θ value	6.88961 (rank : 255)	NC score	-0.000713 (rank : 315)
Query Neighborhood Hits	307	Target Neighborhood Hits	370	Shared Neighborhood Hits	19
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

IQEC2_HUMAN
θ value	6.88961 (rank : 256)	NC score	0.017998 (rank : 197)
Query Neighborhood Hits	307	Target Neighborhood Hits	403	Shared Neighborhood Hits	31
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

JIP4_MOUSE
θ value	6.88961 (rank : 257)	NC score	0.007863 (rank : 261)
Query Neighborhood Hits	307	Target Neighborhood Hits	593	Shared Neighborhood Hits	22
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

KCND1_MOUSE
θ value	6.88961 (rank : 258)	NC score	0.175900 (rank : 54)
Query Neighborhood Hits	307	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

MAP1A_HUMAN
θ value	6.88961 (rank : 259)	NC score	0.022030 (rank : 183)
Query Neighborhood Hits	307	Target Neighborhood Hits	1626	Shared Neighborhood Hits	89
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MUC5B_HUMAN
θ value	6.88961 (rank : 260)	NC score	0.011501 (rank : 240)
Query Neighborhood Hits	307	Target Neighborhood Hits	1020	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SALL3_HUMAN
θ value	6.88961 (rank : 261)	NC score	0.003569 (rank : 288)
Query Neighborhood Hits	307	Target Neighborhood Hits	1066	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SCAR3_MOUSE
θ value	6.88961 (rank : 262)	NC score	0.027881 (rank : 166)
Query Neighborhood Hits	307	Target Neighborhood Hits	239	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

SON_MOUSE
θ value	6.88961 (rank : 263)	NC score	0.033897 (rank : 142)
Query Neighborhood Hits	307	Target Neighborhood Hits	957	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

STAR8_HUMAN
θ value	6.88961 (rank : 264)	NC score	0.007011 (rank : 266)
Query Neighborhood Hits	307	Target Neighborhood Hits	216	Shared Neighborhood Hits	21
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

ZAR1_MOUSE
θ value	6.88961 (rank : 265)	NC score	0.025681 (rank : 175)
Query Neighborhood Hits	307	Target Neighborhood Hits	254	Shared Neighborhood Hits	52
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

ZC11A_HUMAN
θ value	6.88961 (rank : 266)	NC score	0.010574 (rank : 244)
Query Neighborhood Hits	307	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ZC3H5_MOUSE
θ value	6.88961 (rank : 267)	NC score	0.015635 (rank : 212)
Query Neighborhood Hits	307	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

ZDHC1_HUMAN
θ value	6.88961 (rank : 268)	NC score	0.004092 (rank : 282)
Query Neighborhood Hits	307	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

ZN516_MOUSE
θ value	6.88961 (rank : 269)	NC score	0.005587 (rank : 273)
Query Neighborhood Hits	307	Target Neighborhood Hits	1197	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

ZN541_HUMAN
θ value	6.88961 (rank : 270)	NC score	0.010863 (rank : 242)
Query Neighborhood Hits	307	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

AF10_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.010422 (rank : 246)
Query Neighborhood Hits	307	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AUXI_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.014066 (rank : 222)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BNIPL_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.003773 (rank : 286)
Query Neighborhood Hits	307	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BSN_HUMAN
θ value	8.99809 (rank : 274)	NC score	0.051701 (rank : 99)
Query Neighborhood Hits	307	Target Neighborhood Hits	1537	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CO039_MOUSE
θ value	8.99809 (rank : 275)	NC score	0.027947 (rank : 165)
Query Neighborhood Hits	307	Target Neighborhood Hits	445	Shared Neighborhood Hits	49
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

CO1A2_MOUSE
θ value	8.99809 (rank : 276)	NC score	0.041447 (rank : 125)
Query Neighborhood Hits	307	Target Neighborhood Hits	388	Shared Neighborhood Hits	66
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO3A1_MOUSE
θ value	8.99809 (rank : 277)	NC score	0.046213 (rank : 111)
Query Neighborhood Hits	307	Target Neighborhood Hits	466	Shared Neighborhood Hits	79
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

CO8A2_MOUSE
θ value	8.99809 (rank : 278)	NC score	0.031854 (rank : 151)
Query Neighborhood Hits	307	Target Neighborhood Hits	273	Shared Neighborhood Hits	52
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

DCP1B_HUMAN
θ value	8.99809 (rank : 279)	NC score	0.009050 (rank : 256)
Query Neighborhood Hits	307	Target Neighborhood Hits	118	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

DZIP1_HUMAN
θ value	8.99809 (rank : 280)	NC score	0.002785 (rank : 293)
Query Neighborhood Hits	307	Target Neighborhood Hits	675	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

EPN2_HUMAN
θ value	8.99809 (rank : 281)	NC score	0.012203 (rank : 235)
Query Neighborhood Hits	307	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

ETV5_HUMAN
θ value	8.99809 (rank : 282)	NC score	0.002322 (rank : 298)
Query Neighborhood Hits	307	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

FOXE3_HUMAN
θ value	8.99809 (rank : 283)	NC score	0.000402 (rank : 309)
Query Neighborhood Hits	307	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	Q13461, Q5SVY9, Q9NQV9	Gene names	FOXE3, FKHL12, FREAC8
Domain Architecture
Description	Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead- related transcription factor 8) (FREAC-8).

FREA_MOUSE
θ value	8.99809 (rank : 284)	NC score	0.001598 (rank : 301)
Query Neighborhood Hits	307	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

FRS3_HUMAN
θ value	8.99809 (rank : 285)	NC score	0.009187 (rank : 254)
Query Neighborhood Hits	307	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

FRS3_MOUSE
θ value	8.99809 (rank : 286)	NC score	0.013534 (rank : 224)
Query Neighborhood Hits	307	Target Neighborhood Hits	168	Shared Neighborhood Hits	33
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

HSF1_HUMAN
θ value	8.99809 (rank : 287)	NC score	0.013231 (rank : 228)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

HXD11_MOUSE
θ value	8.99809 (rank : 288)	NC score	-0.000642 (rank : 314)
Query Neighborhood Hits	307	Target Neighborhood Hits	376	Shared Neighborhood Hits	16
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

HXK4_HUMAN
θ value	8.99809 (rank : 289)	NC score	0.002865 (rank : 292)
Query Neighborhood Hits	307	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

IRS2_MOUSE
θ value	8.99809 (rank : 290)	NC score	0.028638 (rank : 162)
Query Neighborhood Hits	307	Target Neighborhood Hits	248	Shared Neighborhood Hits	41
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

JHD2B_MOUSE
θ value	8.99809 (rank : 291)	NC score	0.005294 (rank : 275)
Query Neighborhood Hits	307	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

K0460_HUMAN
θ value	8.99809 (rank : 292)	NC score	0.013397 (rank : 225)
Query Neighborhood Hits	307	Target Neighborhood Hits	357	Shared Neighborhood Hits	26
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KCNA6_HUMAN
θ value	8.99809 (rank : 293)	NC score	0.104039 (rank : 68)
Query Neighborhood Hits	307	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KIRR2_HUMAN
θ value	8.99809 (rank : 294)	NC score	0.002480 (rank : 296)
Query Neighborhood Hits	307	Target Neighborhood Hits	321	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

MILK1_HUMAN
θ value	8.99809 (rank : 295)	NC score	0.029334 (rank : 160)
Query Neighborhood Hits	307	Target Neighborhood Hits	427	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MTSS1_MOUSE
θ value	8.99809 (rank : 296)	NC score	0.022630 (rank : 181)
Query Neighborhood Hits	307	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MYCB2_MOUSE
θ value	8.99809 (rank : 297)	NC score	0.007039 (rank : 265)
Query Neighborhood Hits	307	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

PRP1_HUMAN
θ value	8.99809 (rank : 298)	NC score	0.058275 (rank : 92)
Query Neighborhood Hits	307	Target Neighborhood Hits	385	Shared Neighborhood Hits	63
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

REXO1_HUMAN
θ value	8.99809 (rank : 299)	NC score	0.029886 (rank : 159)
Query Neighborhood Hits	307	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RP3A_MOUSE
θ value	8.99809 (rank : 300)	NC score	0.018328 (rank : 195)
Query Neighborhood Hits	307	Target Neighborhood Hits	510	Shared Neighborhood Hits	67
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

RPA1_HUMAN
θ value	8.99809 (rank : 301)	NC score	0.003436 (rank : 289)
Query Neighborhood Hits	307	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

SOX30_MOUSE
θ value	8.99809 (rank : 302)	NC score	0.003946 (rank : 284)
Query Neighborhood Hits	307	Target Neighborhood Hits	374	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TAF5_MOUSE
θ value	8.99809 (rank : 303)	NC score	-0.000380 (rank : 313)
Query Neighborhood Hits	307	Target Neighborhood Hits	366	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TRI47_HUMAN
θ value	8.99809 (rank : 304)	NC score	0.000554 (rank : 308)
Query Neighborhood Hits	307	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRPC4_HUMAN
θ value	8.99809 (rank : 305)	NC score	0.027609 (rank : 168)
Query Neighborhood Hits	307	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	8.99809 (rank : 306)	NC score	0.026629 (rank : 172)
Query Neighborhood Hits	307	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

ZAR1_HUMAN
θ value	8.99809 (rank : 307)	NC score	0.027867 (rank : 167)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	36
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

GGN_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.050469 (rank : 102)
Query Neighborhood Hits	307	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

KCNA3_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.100591 (rank : 71)
Query Neighborhood Hits	307	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.098576 (rank : 73)
Query Neighborhood Hits	307	Target Neighborhood Hits	103	Shared Neighborhood Hits	38
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.087594 (rank : 79)
Query Neighborhood Hits	307	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.087941 (rank : 78)
Query Neighborhood Hits	307	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.096465 (rank : 75)
Query Neighborhood Hits	307	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.100838 (rank : 70)
Query Neighborhood Hits	307	Target Neighborhood Hits	119	Shared Neighborhood Hits	44
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.106276 (rank : 67)
Query Neighborhood Hits	307	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.106405 (rank : 66)
Query Neighborhood Hits	307	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.102560 (rank : 69)
Query Neighborhood Hits	307	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG4_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.100031 (rank : 72)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ2_HUMAN
θ value	θ > 10 (rank : 319)	NC score	0.069009 (rank : 84)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	θ > 10 (rank : 320)	NC score	0.066594 (rank : 86)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 321)	NC score	0.069667 (rank : 83)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	42
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 322)	NC score	0.068745 (rank : 85)
Query Neighborhood Hits	307	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ4_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.093026 (rank : 76)
Query Neighborhood Hits	307	Target Neighborhood Hits	136	Shared Neighborhood Hits	46
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.080852 (rank : 82)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

PKD2_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.236064 (rank : 42)
Query Neighborhood Hits	307	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PKDRE_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.061383 (rank : 89)
Query Neighborhood Hits	307	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PRP5_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.058495 (rank : 91)
Query Neighborhood Hits	307	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

Hits sorted by NC score

CAC1H_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	307	Target Neighborhood Hits	307	Shared Neighborhood Hits	307
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

CAC1H_MOUSE
NC score	0.984657 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	307	Target Neighborhood Hits	230	Shared Neighborhood Hits	105
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1I_HUMAN
NC score	0.977156 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	307	Target Neighborhood Hits	138	Shared Neighborhood Hits	74
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1G_HUMAN
NC score	0.951156 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	307	Target Neighborhood Hits	587	Shared Neighborhood Hits	127
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SC11A_HUMAN
NC score	0.885626 (rank : 5)	θ value	1.00358e-83 (rank : 5)
Query Neighborhood Hits	307	Target Neighborhood Hits	111	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
NC score	0.884099 (rank : 6)	θ value	1.11217e-74 (rank : 6)
Query Neighborhood Hits	307	Target Neighborhood Hits	116	Shared Neighborhood Hits	70
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1E_MOUSE
NC score	0.877552 (rank : 7)	θ value	5.91091e-68 (rank : 15)
Query Neighborhood Hits	307	Target Neighborhood Hits	167	Shared Neighborhood Hits	64
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.877341 (rank : 8)	θ value	3.4653e-68 (rank : 14)
Query Neighborhood Hits	307	Target Neighborhood Hits	148	Shared Neighborhood Hits	63
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN4A_HUMAN
NC score	0.877043 (rank : 9)	θ value	1.7756e-72 (rank : 8)
Query Neighborhood Hits	307	Target Neighborhood Hits	133	Shared Neighborhood Hits	71
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

CAC1S_MOUSE
NC score	0.873680 (rank : 10)	θ value	8.81223e-72 (rank : 11)
Query Neighborhood Hits	307	Target Neighborhood Hits	98	Shared Neighborhood Hits	62
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN5A_HUMAN
NC score	0.873663 (rank : 11)	θ value	5.17823e-64 (rank : 20)
Query Neighborhood Hits	307	Target Neighborhood Hits	145	Shared Neighborhood Hits	67
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1D_HUMAN
NC score	0.872910 (rank : 12)	θ value	1.35953e-72 (rank : 7)
Query Neighborhood Hits	307	Target Neighborhood Hits	118	Shared Neighborhood Hits	66
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1A_MOUSE
NC score	0.872762 (rank : 13)	θ value	2.17557e-62 (rank : 26)
Query Neighborhood Hits	307	Target Neighborhood Hits	267	Shared Neighborhood Hits	93
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1S_HUMAN
NC score	0.872252 (rank : 14)	θ value	5.91091e-68 (rank : 16)
Query Neighborhood Hits	307	Target Neighborhood Hits	92	Shared Neighborhood Hits	61
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN3A_HUMAN
NC score	0.870292 (rank : 15)	θ value	2.31901e-72 (rank : 9)
Query Neighborhood Hits	307	Target Neighborhood Hits	115	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN7A_HUMAN
NC score	0.869295 (rank : 16)	θ value	1.31987e-59 (rank : 28)
Query Neighborhood Hits	307	Target Neighborhood Hits	135	Shared Neighborhood Hits	60
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1A_HUMAN
NC score	0.869069 (rank : 17)	θ value	1.96772e-63 (rank : 23)
Query Neighborhood Hits	307	Target Neighborhood Hits	387	Shared Neighborhood Hits	118
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
NC score	0.868752 (rank : 18)	θ value	3.35642e-63 (rank : 25)
Query Neighborhood Hits	307	Target Neighborhood Hits	257	Shared Neighborhood Hits	75
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_HUMAN
NC score	0.867686 (rank : 19)	θ value	3.58603e-65 (rank : 19)
Query Neighborhood Hits	307	Target Neighborhood Hits	141	Shared Neighborhood Hits	72
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1B_MOUSE
NC score	0.867457 (rank : 20)	θ value	3.83135e-67 (rank : 17)
Query Neighborhood Hits	307	Target Neighborhood Hits	351	Shared Neighborhood Hits	93
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1F_MOUSE
NC score	0.867251 (rank : 21)	θ value	1.15359e-63 (rank : 22)
Query Neighborhood Hits	307	Target Neighborhood Hits	142	Shared Neighborhood Hits	68
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SCN2A_HUMAN
NC score	0.866209 (rank : 22)	θ value	3.95564e-72 (rank : 10)
Query Neighborhood Hits	307	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
NC score	0.866034 (rank : 23)	θ value	1.66191e-70 (rank : 12)
Query Neighborhood Hits	307	Target Neighborhood Hits	157	Shared Neighborhood Hits	63
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1C_MOUSE
NC score	0.865666 (rank : 24)	θ value	1.6097e-65 (rank : 18)
Query Neighborhood Hits	307	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SCN1A_HUMAN
NC score	0.865624 (rank : 25)	θ value	3.13423e-69 (rank : 13)
Query Neighborhood Hits	307	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SC10A_MOUSE
NC score	0.864951 (rank : 26)	θ value	4.53632e-60 (rank : 27)
Query Neighborhood Hits	307	Target Neighborhood Hits	107	Shared Neighborhood Hits	65
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN8A_HUMAN
NC score	0.864236 (rank : 27)	θ value	6.76295e-64 (rank : 21)
Query Neighborhood Hits	307	Target Neighborhood Hits	135	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SC10A_HUMAN
NC score	0.863336 (rank : 28)	θ value	1.11734e-58 (rank : 29)
Query Neighborhood Hits	307	Target Neighborhood Hits	116	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
NC score	0.861997 (rank : 29)	θ value	2.56992e-63 (rank : 24)
Query Neighborhood Hits	307	Target Neighborhood Hits	136	Shared Neighborhood Hits	63
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1C_HUMAN
NC score	0.859437 (rank : 30)	θ value	1.90589e-58 (rank : 30)
Query Neighborhood Hits	307	Target Neighborhood Hits	158	Shared Neighborhood Hits	64
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

PK2L2_HUMAN
NC score	0.289441 (rank : 31)	θ value	0.21417 (rank : 77)
Query Neighborhood Hits	307	Target Neighborhood Hits	90	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.274069 (rank : 32)	θ value	0.0961366 (rank : 64)
Query Neighborhood Hits	307	Target Neighborhood Hits	132	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCNV2_HUMAN
NC score	0.267503 (rank : 33)	θ value	6.43352e-06 (rank : 35)
Query Neighborhood Hits	307	Target Neighborhood Hits	137	Shared Neighborhood Hits	60
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNF1_HUMAN
NC score	0.262557 (rank : 34)	θ value	0.0148317 (rank : 49)
Query Neighborhood Hits	307	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

PK2L2_MOUSE
NC score	0.256400 (rank : 35)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	307	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

KCNB2_HUMAN
NC score	0.252145 (rank : 36)	θ value	1.09739e-05 (rank : 37)
Query Neighborhood Hits	307	Target Neighborhood Hits	212	Shared Neighborhood Hits	67
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

PKD2_MOUSE
NC score	0.251857 (rank : 37)	θ value	0.813845 (rank : 106)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

KCNS2_MOUSE
NC score	0.249810 (rank : 38)	θ value	3.77169e-06 (rank : 34)
Query Neighborhood Hits	307	Target Neighborhood Hits	130	Shared Neighborhood Hits	62
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.245381 (rank : 39)	θ value	8.40245e-06 (rank : 36)
Query Neighborhood Hits	307	Target Neighborhood Hits	129	Shared Neighborhood Hits	61
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_HUMAN
NC score	0.242121 (rank : 40)	θ value	5.81887e-07 (rank : 32)
Query Neighborhood Hits	307	Target Neighborhood Hits	169	Shared Neighborhood Hits	63
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
NC score	0.242045 (rank : 41)	θ value	5.81887e-07 (rank : 33)
Query Neighborhood Hits	307	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

PKD2_HUMAN
NC score	0.236064 (rank : 42)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	307	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNS3_HUMAN
NC score	0.214671 (rank : 43)	θ value	0.00390308 (rank : 44)
Query Neighborhood Hits	307	Target Neighborhood Hits	125	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND3_MOUSE
NC score	0.199511 (rank : 44)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	307	Target Neighborhood Hits	162	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.199330 (rank : 45)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	307	Target Neighborhood Hits	162	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND2_MOUSE
NC score	0.198167 (rank : 46)	θ value	0.00509761 (rank : 46)
Query Neighborhood Hits	307	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.197726 (rank : 47)	θ value	0.00665767 (rank : 47)
Query Neighborhood Hits	307	Target Neighborhood Hits	154	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNS1_HUMAN
NC score	0.193736 (rank : 48)	θ value	0.000158464 (rank : 40)
Query Neighborhood Hits	307	Target Neighborhood Hits	116	Shared Neighborhood Hits	60
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
NC score	0.191240 (rank : 49)	θ value	9.29e-05 (rank : 39)
Query Neighborhood Hits	307	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNS1_MOUSE
NC score	0.182987 (rank : 50)	θ value	3.19293e-05 (rank : 38)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	54
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNC1_HUMAN
NC score	0.180980 (rank : 51)	θ value	0.00228821 (rank : 43)
Query Neighborhood Hits	307	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.179656 (rank : 52)	θ value	0.00175202 (rank : 42)
Query Neighborhood Hits	307	Target Neighborhood Hits	133	Shared Neighborhood Hits	57
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCND1_HUMAN
NC score	0.176158 (rank : 53)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	307	Target Neighborhood Hits	160	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
NC score	0.175900 (rank : 54)	θ value	6.88961 (rank : 258)
Query Neighborhood Hits	307	Target Neighborhood Hits	165	Shared Neighborhood Hits	60
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNC4_HUMAN
NC score	0.165021 (rank : 55)	θ value	0.0736092 (rank : 62)
Query Neighborhood Hits	307	Target Neighborhood Hits	141	Shared Neighborhood Hits	58
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC3_HUMAN
NC score	0.155404 (rank : 56)	θ value	0.0736092 (rank : 61)
Query Neighborhood Hits	307	Target Neighborhood Hits	256	Shared Neighborhood Hits	81
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_MOUSE
NC score	0.153224 (rank : 57)	θ value	3.0926 (rank : 180)
Query Neighborhood Hits	307	Target Neighborhood Hits	130	Shared Neighborhood Hits	55
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_MOUSE
NC score	0.151518 (rank : 58)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	307	Target Neighborhood Hits	173	Shared Neighborhood Hits	59
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

TPTE_HUMAN
NC score	0.141254 (rank : 59)	θ value	0.00390308 (rank : 45)
Query Neighborhood Hits	307	Target Neighborhood Hits	53	Shared Neighborhood Hits	25
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNG3_HUMAN
NC score	0.136365 (rank : 60)	θ value	5.27518 (rank : 228)
Query Neighborhood Hits	307	Target Neighborhood Hits	91	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.135507 (rank : 61)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	307	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA1_MOUSE
NC score	0.115828 (rank : 62)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	307	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.113463 (rank : 63)	θ value	4.03905 (rank : 202)
Query Neighborhood Hits	307	Target Neighborhood Hits	104	Shared Neighborhood Hits	44
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_MOUSE
NC score	0.111427 (rank : 64)	θ value	4.03905 (rank : 204)
Query Neighborhood Hits	307	Target Neighborhood Hits	102	Shared Neighborhood Hits	43
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.110069 (rank : 65)	θ value	4.03905 (rank : 203)
Query Neighborhood Hits	307	Target Neighborhood Hits	101	Shared Neighborhood Hits	42
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNG1_HUMAN
NC score	0.106405 (rank : 66)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	307	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNA6_MOUSE
NC score	0.106276 (rank : 67)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	307	Target Neighborhood Hits	106	Shared Neighborhood Hits	44
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA6_HUMAN
NC score	0.104039 (rank : 68)	θ value	8.99809 (rank : 293)
Query Neighborhood Hits	307	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNG2_HUMAN
NC score	0.102560 (rank : 69)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	307	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA5_MOUSE
NC score	0.100838 (rank : 70)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	307	Target Neighborhood Hits	119	Shared Neighborhood Hits	44
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA3_HUMAN
NC score	0.100591 (rank : 71)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	307	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNG4_HUMAN
NC score	0.100031 (rank : 72)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA3_MOUSE
NC score	0.098576 (rank : 73)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	307	Target Neighborhood Hits	103	Shared Neighborhood Hits	38
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNQ1_MOUSE
NC score	0.097057 (rank : 74)	θ value	3.0926 (rank : 181)
Query Neighborhood Hits	307	Target Neighborhood Hits	175	Shared Neighborhood Hits	53
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA5_HUMAN
NC score	0.096465 (rank : 75)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	307	Target Neighborhood Hits	124	Shared Neighborhood Hits	40
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNQ4_HUMAN
NC score	0.093026 (rank : 76)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	307	Target Neighborhood Hits	136	Shared Neighborhood Hits	46
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

PKDRE_HUMAN
NC score	0.090949 (rank : 77)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	307	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNA4_MOUSE
NC score	0.087941 (rank : 78)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	307	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.087594 (rank : 79)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	307	Target Neighborhood Hits	108	Shared Neighborhood Hits	33
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNQ1_HUMAN
NC score	0.086902 (rank : 80)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	42
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

MARCS_HUMAN
NC score	0.081359 (rank : 81)	θ value	0.00869519 (rank : 48)
Query Neighborhood Hits	307	Target Neighborhood Hits	204	Shared Neighborhood Hits	36
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

KCNQ5_HUMAN
NC score	0.080852 (rank : 82)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ3_HUMAN
NC score	0.069667 (rank : 83)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	42
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_HUMAN
NC score	0.069009 (rank : 84)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	43
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_MOUSE
NC score	0.068745 (rank : 85)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	307	Target Neighborhood Hits	105	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_MOUSE
NC score	0.066594 (rank : 86)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

TRPV3_HUMAN
NC score	0.062571 (rank : 87)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	307	Target Neighborhood Hits	198	Shared Neighborhood Hits	27
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

BSN_MOUSE
NC score	0.062018 (rank : 88)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	307	Target Neighborhood Hits	2057	Shared Neighborhood Hits	169
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PKDRE_MOUSE
NC score	0.061383 (rank : 89)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	307	Target Neighborhood Hits	76	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

BASP_MOUSE
NC score	0.059185 (rank : 90)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	307	Target Neighborhood Hits	260	Shared Neighborhood Hits	37
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

PRP5_HUMAN
NC score	0.058495 (rank : 91)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	307	Target Neighborhood Hits	108	Shared Neighborhood Hits	27
SwissProt Accessions	P04281	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide IB-1.

PRP1_HUMAN
NC score	0.058275 (rank : 92)	θ value	8.99809 (rank : 298)
Query Neighborhood Hits	307	Target Neighborhood Hits	385	Shared Neighborhood Hits	63
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

SRRM1_MOUSE
NC score	0.057974 (rank : 93)	θ value	2.36792 (rank : 166)
Query Neighborhood Hits	307	Target Neighborhood Hits	966	Shared Neighborhood Hits	93
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

MCLN2_MOUSE
NC score	0.055333 (rank : 94)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	307	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

CJ012_HUMAN
NC score	0.055301 (rank : 95)	θ value	0.00102713 (rank : 41)
Query Neighborhood Hits	307	Target Neighborhood Hits	467	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CO1A1_MOUSE
NC score	0.054347 (rank : 96)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	307	Target Neighborhood Hits	457	Shared Neighborhood Hits	88
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

WASIP_HUMAN
NC score	0.053247 (rank : 97)	θ value	1.06291 (rank : 115)
Query Neighborhood Hits	307	Target Neighborhood Hits	458	Shared Neighborhood Hits	57
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

CO5A1_HUMAN
NC score	0.053186 (rank : 98)	θ value	0.0193708 (rank : 51)
Query Neighborhood Hits	307	Target Neighborhood Hits	434	Shared Neighborhood Hits	75
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

BSN_HUMAN
NC score	0.051701 (rank : 99)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	307	Target Neighborhood Hits	1537	Shared Neighborhood Hits	130
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CO5A1_MOUSE
NC score	0.051217 (rank : 100)	θ value	0.0736092 (rank : 59)
Query Neighborhood Hits	307	Target Neighborhood Hits	419	Shared Neighborhood Hits	70
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

TAU_HUMAN
NC score	0.050812 (rank : 101)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	307	Target Neighborhood Hits	448	Shared Neighborhood Hits	81
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

GGN_HUMAN
NC score	0.050469 (rank : 102)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	307	Target Neighborhood Hits	269	Shared Neighborhood Hits	37
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CO1A1_HUMAN
NC score	0.050132 (rank : 103)	θ value	0.47712 (rank : 89)
Query Neighborhood Hits	307	Target Neighborhood Hits	475	Shared Neighborhood Hits	86
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO3A1_HUMAN
NC score	0.049726 (rank : 104)	θ value	6.88961 (rank : 248)
Query Neighborhood Hits	307	Target Neighborhood Hits	452	Shared Neighborhood Hits	79
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

MARCS_MOUSE
NC score	0.049607 (rank : 105)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	307	Target Neighborhood Hits	227	Shared Neighborhood Hits	32
SwissProt Accessions	P26645	Gene names	Marcks, Macs
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS).

TAF4_HUMAN
NC score	0.048945 (rank : 106)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	307	Target Neighborhood Hits	687	Shared Neighborhood Hits	70
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

BASP_HUMAN
NC score	0.048531 (rank : 107)	θ value	0.62314 (rank : 95)
Query Neighborhood Hits	307	Target Neighborhood Hits	321	Shared Neighborhood Hits	45
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_HUMAN
NC score	0.048002 (rank : 108)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	307	Target Neighborhood Hits	931	Shared Neighborhood Hits	100
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

PCLO_HUMAN
NC score	0.047866 (rank : 109)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	307	Target Neighborhood Hits	2046	Shared Neighborhood Hits	121
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CO2A1_HUMAN
NC score	0.046426 (rank : 110)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	307	Target Neighborhood Hits	486	Shared Neighborhood Hits	80
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO3A1_MOUSE
NC score	0.046213 (rank : 111)	θ value	8.99809 (rank : 277)
Query Neighborhood Hits	307	Target Neighborhood Hits	466	Shared Neighborhood Hits	79
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

SNPC4_HUMAN
NC score	0.045008 (rank : 112)	θ value	0.0431538 (rank : 57)
Query Neighborhood Hits	307	Target Neighborhood Hits	589	Shared Neighborhood Hits	80
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

RGS3_MOUSE
NC score	0.044978 (rank : 113)	θ value	0.47712 (rank : 93)
Query Neighborhood Hits	307	Target Neighborhood Hits	1621	Shared Neighborhood Hits	140
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CTDP1_HUMAN
NC score	0.044718 (rank : 114)	θ value	0.0736092 (rank : 60)
Query Neighborhood Hits	307	Target Neighborhood Hits	416	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

CO1A2_HUMAN
NC score	0.044599 (rank : 115)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	307	Target Neighborhood Hits	329	Shared Neighborhood Hits	66
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

MUC1_HUMAN
NC score	0.044349 (rank : 116)	θ value	0.0193708 (rank : 53)
Query Neighborhood Hits	307	Target Neighborhood Hits	975	Shared Neighborhood Hits	105
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CO2A1_MOUSE
NC score	0.043076 (rank : 117)	θ value	4.03905 (rank : 194)
Query Neighborhood Hits	307	Target Neighborhood Hits	483	Shared Neighborhood Hits	73
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

ENAH_MOUSE
NC score	0.042874 (rank : 118)	θ value	0.0193708 (rank : 52)
Query Neighborhood Hits	307	Target Neighborhood Hits	919	Shared Neighborhood Hits	63
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

NFH_MOUSE
NC score	0.042615 (rank : 119)	θ value	4.0297e-08 (rank : 31)
Query Neighborhood Hits	307	Target Neighborhood Hits	2247	Shared Neighborhood Hits	146
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

COBA1_MOUSE
NC score	0.042605 (rank : 120)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	307	Target Neighborhood Hits	487	Shared Neighborhood Hits	76
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA2_HUMAN
NC score	0.042396 (rank : 121)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	307	Target Neighborhood Hits	408	Shared Neighborhood Hits	72
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

PRRT3_HUMAN
NC score	0.042385 (rank : 122)	θ value	4.03905 (rank : 209)
Query Neighborhood Hits	307	Target Neighborhood Hits	998	Shared Neighborhood Hits	108
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

COBA1_HUMAN
NC score	0.042225 (rank : 123)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	307	Target Neighborhood Hits	491	Shared Neighborhood Hits	78
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

PCLO_MOUSE
NC score	0.041533 (rank : 124)	θ value	0.0252991 (rank : 54)
Query Neighborhood Hits	307	Target Neighborhood Hits	2275	Shared Neighborhood Hits	155
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CO1A2_MOUSE
NC score	0.041447 (rank : 125)	θ value	8.99809 (rank : 276)
Query Neighborhood Hits	307	Target Neighborhood Hits	388	Shared Neighborhood Hits	66
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO4A4_HUMAN
NC score	0.041397 (rank : 126)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	307	Target Neighborhood Hits	440	Shared Neighborhood Hits	71
SwissProt Accessions	P53420	Gene names	COL4A4
Domain Architecture
Description	Collagen alpha-4(IV) chain precursor.

GRIN2_HUMAN
NC score	0.041016 (rank : 127)	θ value	0.0431538 (rank : 56)
Query Neighborhood Hits	307	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	O60269, Q5SVF0	Gene names	GPRIN2, KIAA0514
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 2 (GRIN2).

CO5A2_HUMAN
NC score	0.040776 (rank : 128)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	307	Target Neighborhood Hits	760	Shared Neighborhood Hits	96
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

COBA2_MOUSE
NC score	0.040758 (rank : 129)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	307	Target Neighborhood Hits	501	Shared Neighborhood Hits	76
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

CGRE1_HUMAN
NC score	0.039640 (rank : 130)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	307	Target Neighborhood Hits	354	Shared Neighborhood Hits	57
SwissProt Accessions	Q99674	Gene names	CGREF1, CGR11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

TAU_MOUSE
NC score	0.038463 (rank : 131)	θ value	3.0926 (rank : 192)
Query Neighborhood Hits	307	Target Neighborhood Hits	502	Shared Neighborhood Hits	75
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

CO002_HUMAN
NC score	0.038293 (rank : 132)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	307	Target Neighborhood Hits	387	Shared Neighborhood Hits	58
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CABIN_HUMAN
NC score	0.038140 (rank : 133)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	307	Target Neighborhood Hits	490	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

S36A1_MOUSE
NC score	0.037865 (rank : 134)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	307	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4D3, Q811N9	Gene names	Slc36a1, Pat1
Domain Architecture	No domain graphic available
Description	Proton-coupled amino acid transporter 1 (Proton/amino acid transporter 1) (Solute carrier family 36 member 1).

MILK1_MOUSE
NC score	0.036458 (rank : 135)	θ value	4.03905 (rank : 206)
Query Neighborhood Hits	307	Target Neighborhood Hits	788	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

GP179_HUMAN
NC score	0.036443 (rank : 136)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	307	Target Neighborhood Hits	372	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

PK1L1_HUMAN
NC score	0.035642 (rank : 137)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	307	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

NCOR2_HUMAN
NC score	0.035391 (rank : 138)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	307	Target Neighborhood Hits	870	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

RGS3_HUMAN
NC score	0.035344 (rank : 139)	θ value	0.0148317 (rank : 50)
Query Neighborhood Hits	307	Target Neighborhood Hits	1375	Shared Neighborhood Hits	119
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TB182_HUMAN
NC score	0.035122 (rank : 140)	θ value	5.27518 (rank : 239)
Query Neighborhood Hits	307	Target Neighborhood Hits	414	Shared Neighborhood Hits	64
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

CO039_HUMAN
NC score	0.034607 (rank : 141)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	307	Target Neighborhood Hits	264	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

SON_MOUSE
NC score	0.033897 (rank : 142)	θ value	6.88961 (rank : 263)
Query Neighborhood Hits	307	Target Neighborhood Hits	957	Shared Neighborhood Hits	92
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MBB1A_HUMAN
NC score	0.033821 (rank : 143)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	307	Target Neighborhood Hits	665	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CO7A1_HUMAN
NC score	0.033365 (rank : 144)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	307	Target Neighborhood Hits	807	Shared Neighborhood Hits	85
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO8A2_HUMAN
NC score	0.032774 (rank : 145)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	307	Target Neighborhood Hits	299	Shared Neighborhood Hits	54
SwissProt Accessions	P25067, Q8TEJ5	Gene names	COL8A2
Domain Architecture
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

EDN3_HUMAN
NC score	0.032739 (rank : 146)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	307	Target Neighborhood Hits	61	Shared Neighborhood Hits	15
SwissProt Accessions	P14138, Q03229	Gene names	EDN3
Domain Architecture
Description	Endothelin-3 precursor (ET-3) (Preproendothelin-3) (PPET3).

COAA1_MOUSE
NC score	0.032298 (rank : 147)	θ value	4.03905 (rank : 195)
Query Neighborhood Hits	307	Target Neighborhood Hits	286	Shared Neighborhood Hits	49
SwissProt Accessions	Q05306	Gene names	Col10a1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

MAGE1_HUMAN
NC score	0.032268 (rank : 148)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	307	Target Neighborhood Hits	1389	Shared Neighborhood Hits	127
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FA8A1_HUMAN
NC score	0.032122 (rank : 149)	θ value	0.62314 (rank : 96)
Query Neighborhood Hits	307	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UBU6	Gene names	FAM8A1, AHCP
Domain Architecture	No domain graphic available
Description	Protein FAM8A1 (Autosomal highly conserved protein).

COAA1_HUMAN
NC score	0.032066 (rank : 150)	θ value	6.88961 (rank : 250)
Query Neighborhood Hits	307	Target Neighborhood Hits	316	Shared Neighborhood Hits	58
SwissProt Accessions	Q03692	Gene names	COL10A1
Domain Architecture
Description	Collagen alpha-1(X) chain precursor.

CO8A2_MOUSE
NC score	0.031854 (rank : 151)	θ value	8.99809 (rank : 278)
Query Neighborhood Hits	307	Target Neighborhood Hits	273	Shared Neighborhood Hits	52
SwissProt Accessions	P25318, Q68ED0, Q6KAQ4, Q6P1C4	Gene names	Col8a2
Domain Architecture	No domain graphic available
Description	Collagen alpha-2(VIII) chain precursor (Endothelial collagen).

DOT1L_HUMAN
NC score	0.031762 (rank : 152)	θ value	4.03905 (rank : 196)
Query Neighborhood Hits	307	Target Neighborhood Hits	660	Shared Neighborhood Hits	68
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

CXXC6_HUMAN
NC score	0.031606 (rank : 153)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	307	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

CO4A2_MOUSE
NC score	0.031344 (rank : 154)	θ value	6.88961 (rank : 249)
Query Neighborhood Hits	307	Target Neighborhood Hits	492	Shared Neighborhood Hits	69
SwissProt Accessions	P08122, Q61375	Gene names	Col4a2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

TNC6B_HUMAN
NC score	0.030760 (rank : 155)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	307	Target Neighborhood Hits	256	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

GA2L1_MOUSE
NC score	0.030559 (rank : 156)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	307	Target Neighborhood Hits	114	Shared Neighborhood Hits	19
SwissProt Accessions	Q8JZP9, Q5SVG0, Q8K573	Gene names	Gas2l1
Domain Architecture	No domain graphic available
Description	GAS2-like protein 1 (Growth arrest-specific 2-like 1).

GTSE1_HUMAN
NC score	0.029892 (rank : 157)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	307	Target Neighborhood Hits	193	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NYZ3, Q53GX5, Q5R3I6, Q6DHX4, Q9BRE0, Q9UGZ9, Q9Y557	Gene names	GTSE1
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (B99 homolog).

T240L_HUMAN
NC score	0.029892 (rank : 158)	θ value	0.0330416 (rank : 55)
Query Neighborhood Hits	307	Target Neighborhood Hits	132	Shared Neighborhood Hits	16
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

REXO1_HUMAN
NC score	0.029886 (rank : 159)	θ value	8.99809 (rank : 299)
Query Neighborhood Hits	307	Target Neighborhood Hits	242	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

MILK1_HUMAN
NC score	0.029334 (rank : 160)	θ value	8.99809 (rank : 295)
Query Neighborhood Hits	307	Target Neighborhood Hits	427	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RUSC2_MOUSE
NC score	0.029313 (rank : 161)	θ value	3.0926 (rank : 188)
Query Neighborhood Hits	307	Target Neighborhood Hits	305	Shared Neighborhood Hits	45
SwissProt Accessions	Q80U22, Q8R1D6	Gene names	Rusc2, Kiaa0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

IRS2_MOUSE
NC score	0.028638 (rank : 162)	θ value	8.99809 (rank : 290)
Query Neighborhood Hits	307	Target Neighborhood Hits	248	Shared Neighborhood Hits	41
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

HCN4_HUMAN
NC score	0.028504 (rank : 163)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	307	Target Neighborhood Hits	303	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

CO6A1_HUMAN
NC score	0.028128 (rank : 164)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	307	Target Neighborhood Hits	264	Shared Neighborhood Hits	41
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO039_MOUSE
NC score	0.027947 (rank : 165)	θ value	8.99809 (rank : 275)
Query Neighborhood Hits	307	Target Neighborhood Hits	445	Shared Neighborhood Hits	49
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SCAR3_MOUSE
NC score	0.027881 (rank : 166)	θ value	6.88961 (rank : 262)
Query Neighborhood Hits	307	Target Neighborhood Hits	239	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C850, Q8C6N1	Gene names	Scara3
Domain Architecture	No domain graphic available
Description	Scavenger receptor class A member 3.

ZAR1_HUMAN
NC score	0.027867 (rank : 167)	θ value	8.99809 (rank : 307)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	36
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

TRPC4_HUMAN
NC score	0.027609 (rank : 168)	θ value	8.99809 (rank : 305)
Query Neighborhood Hits	307	Target Neighborhood Hits	140	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

CF057_HUMAN
NC score	0.027279 (rank : 169)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	307	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VUM1	Gene names	C6orf57
Domain Architecture	No domain graphic available
Description	UPF0369 protein C6orf57 precursor.

GPTC8_HUMAN
NC score	0.027032 (rank : 170)	θ value	5.27518 (rank : 225)
Query Neighborhood Hits	307	Target Neighborhood Hits	366	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

TOIP2_MOUSE
NC score	0.026737 (rank : 171)	θ value	1.81305 (rank : 145)
Query Neighborhood Hits	307	Target Neighborhood Hits	115	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYU6, Q6NY10, Q8BJP0	Gene names	Tor1aip2
Domain Architecture	No domain graphic available
Description	Torsin-1A-interacting protein 2.

TRPC4_MOUSE
NC score	0.026629 (rank : 172)	θ value	8.99809 (rank : 306)
Query Neighborhood Hits	307	Target Neighborhood Hits	141	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

MLL3_MOUSE
NC score	0.026343 (rank : 173)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	307	Target Neighborhood Hits	1399	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SFTPD_MOUSE
NC score	0.025965 (rank : 174)	θ value	5.27518 (rank : 235)
Query Neighborhood Hits	307	Target Neighborhood Hits	217	Shared Neighborhood Hits	44
SwissProt Accessions	P50404	Gene names	Sftpd, Sftp4
Domain Architecture
Description	Pulmonary surfactant-associated protein D precursor (SP-D) (PSP-D).

ZAR1_MOUSE
NC score	0.025681 (rank : 175)	θ value	6.88961 (rank : 265)
Query Neighborhood Hits	307	Target Neighborhood Hits	254	Shared Neighborhood Hits	52
SwissProt Accessions	Q80SU3	Gene names	Zar1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

HCN4_MOUSE
NC score	0.025642 (rank : 176)	θ value	0.62314 (rank : 98)
Query Neighborhood Hits	307	Target Neighborhood Hits	284	Shared Neighborhood Hits	43
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

BAG3_MOUSE
NC score	0.025570 (rank : 177)	θ value	6.88961 (rank : 246)
Query Neighborhood Hits	307	Target Neighborhood Hits	513	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

DGKK_HUMAN
NC score	0.024857 (rank : 178)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	307	Target Neighborhood Hits	378	Shared Neighborhood Hits	41
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

TCGAP_HUMAN
NC score	0.023788 (rank : 179)	θ value	1.81305 (rank : 144)
Query Neighborhood Hits	307	Target Neighborhood Hits	872	Shared Neighborhood Hits	81
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

PGCA_HUMAN
NC score	0.022763 (rank : 180)	θ value	3.0926 (rank : 187)
Query Neighborhood Hits	307	Target Neighborhood Hits	821	Shared Neighborhood Hits	72
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

MTSS1_MOUSE
NC score	0.022630 (rank : 181)	θ value	8.99809 (rank : 296)
Query Neighborhood Hits	307	Target Neighborhood Hits	592	Shared Neighborhood Hits	64
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MLL3_HUMAN
NC score	0.022455 (rank : 182)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	307	Target Neighborhood Hits	1644	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAP1A_HUMAN
NC score	0.022030 (rank : 183)	θ value	6.88961 (rank : 259)
Query Neighborhood Hits	307	Target Neighborhood Hits	1626	Shared Neighborhood Hits	89
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

DUT_HUMAN
NC score	0.021405 (rank : 184)	θ value	6.88961 (rank : 252)
Query Neighborhood Hits	307	Target Neighborhood Hits	52	Shared Neighborhood Hits	23
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

UBE4B_HUMAN
NC score	0.021211 (rank : 185)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	307	Target Neighborhood Hits	158	Shared Neighborhood Hits	23
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

MTSS1_HUMAN
NC score	0.021189 (rank : 186)	θ value	5.27518 (rank : 230)
Query Neighborhood Hits	307	Target Neighborhood Hits	504	Shared Neighborhood Hits	59
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

SYNPO_HUMAN
NC score	0.020951 (rank : 187)	θ value	4.03905 (rank : 212)
Query Neighborhood Hits	307	Target Neighborhood Hits	281	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N3V7, O15271, Q9UPX1	Gene names	SYNPO, KIAA1029
Domain Architecture	No domain graphic available
Description	Synaptopodin.

HCN2_HUMAN
NC score	0.020863 (rank : 188)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	307	Target Neighborhood Hits	369	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

CIZ1_HUMAN
NC score	0.020407 (rank : 189)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	307	Target Neighborhood Hits	359	Shared Neighborhood Hits	25
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

T2FA_HUMAN
NC score	0.020131 (rank : 190)	θ value	4.03905 (rank : 213)
Query Neighborhood Hits	307	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	P35269, Q9BWN0	Gene names	GTF2F1, RAP74
Domain Architecture
Description	Transcription initiation factor IIF alpha subunit (EC 2.7.11.1) (TFIIF-alpha) (Transcription initiation factor RAP74) (General transcription factor IIF polypeptide 1 74 kDa subunit protein).

DJBP_HUMAN
NC score	0.019571 (rank : 191)	θ value	0.47712 (rank : 90)
Query Neighborhood Hits	307	Target Neighborhood Hits	156	Shared Neighborhood Hits	7
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

MILK2_HUMAN
NC score	0.019057 (rank : 192)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	307	Target Neighborhood Hits	457	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MAP1B_HUMAN
NC score	0.018648 (rank : 193)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	307	Target Neighborhood Hits	903	Shared Neighborhood Hits	44
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

IQEC2_MOUSE
NC score	0.018521 (rank : 194)	θ value	5.27518 (rank : 226)
Query Neighborhood Hits	307	Target Neighborhood Hits	417	Shared Neighborhood Hits	32
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

RP3A_MOUSE
NC score	0.018328 (rank : 195)	θ value	8.99809 (rank : 300)
Query Neighborhood Hits	307	Target Neighborhood Hits	510	Shared Neighborhood Hits	67
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

PYGO2_HUMAN
NC score	0.018272 (rank : 196)	θ value	4.03905 (rank : 210)
Query Neighborhood Hits	307	Target Neighborhood Hits	189	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

IQEC2_HUMAN
NC score	0.017998 (rank : 197)	θ value	6.88961 (rank : 256)
Query Neighborhood Hits	307	Target Neighborhood Hits	403	Shared Neighborhood Hits	31
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

CEP72_HUMAN
NC score	0.017910 (rank : 198)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	307	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P209, Q9BV03, Q9BWM3, Q9NVR4	Gene names	CEP72, KIAA1519
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

ZC3H5_HUMAN
NC score	0.017906 (rank : 199)	θ value	1.06291 (rank : 116)
Query Neighborhood Hits	307	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q9C0B0	Gene names	ZC3H5, KIAA1753, ZC3HDC5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

SHAN2_MOUSE
NC score	0.017775 (rank : 200)	θ value	3.0926 (rank : 189)
Query Neighborhood Hits	307	Target Neighborhood Hits	446	Shared Neighborhood Hits	33
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

MAP1B_MOUSE
NC score	0.017775 (rank : 201)	θ value	3.0926 (rank : 182)
Query Neighborhood Hits	307	Target Neighborhood Hits	977	Shared Neighborhood Hits	45
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CCD45_MOUSE
NC score	0.017688 (rank : 202)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	307	Target Neighborhood Hits	663	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

AF10_MOUSE
NC score	0.017538 (rank : 203)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	307	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AMPH_HUMAN
NC score	0.017325 (rank : 204)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	307	Target Neighborhood Hits	455	Shared Neighborhood Hits	35
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

ES8L1_MOUSE
NC score	0.017186 (rank : 205)	θ value	0.0563607 (rank : 58)
Query Neighborhood Hits	307	Target Neighborhood Hits	143	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

TRPM2_MOUSE
NC score	0.017143 (rank : 206)	θ value	4.03905 (rank : 214)
Query Neighborhood Hits	307	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

EMIL1_MOUSE
NC score	0.017131 (rank : 207)	θ value	5.27518 (rank : 223)
Query Neighborhood Hits	307	Target Neighborhood Hits	214	Shared Neighborhood Hits	32
SwissProt Accessions	Q99K41	Gene names	Emilin1
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

EPN3_MOUSE
NC score	0.016445 (rank : 208)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	307	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

PAX9_HUMAN
NC score	0.016360 (rank : 209)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	307	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

SIPA1_HUMAN
NC score	0.015979 (rank : 210)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	307	Target Neighborhood Hits	250	Shared Neighborhood Hits	19
SwissProt Accessions	Q96FS4, O14518, O60484, O60618	Gene names	SIPA1, SPA1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1) (p130 SPA-1).

SIPA1_MOUSE
NC score	0.015649 (rank : 211)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	307	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	P46062, P70204	Gene names	Sipa1, Spa-1, Spa1
Domain Architecture
Description	Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase- activating protein Spa-1).

ZC3H5_MOUSE
NC score	0.015635 (rank : 212)	θ value	6.88961 (rank : 267)
Query Neighborhood Hits	307	Target Neighborhood Hits	136	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

SREC2_HUMAN
NC score	0.015548 (rank : 213)	θ value	5.27518 (rank : 237)
Query Neighborhood Hits	307	Target Neighborhood Hits	645	Shared Neighborhood Hits	44
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

RP3A_HUMAN
NC score	0.015533 (rank : 214)	θ value	2.36792 (rank : 165)
Query Neighborhood Hits	307	Target Neighborhood Hits	305	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CS034_HUMAN
NC score	0.015462 (rank : 215)	θ value	6.88961 (rank : 251)
Query Neighborhood Hits	307	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NCQ2	Gene names	C19orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf34.

RPGR1_HUMAN
NC score	0.015381 (rank : 216)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	307	Target Neighborhood Hits	578	Shared Neighborhood Hits	16
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CHSS3_HUMAN
NC score	0.015375 (rank : 217)	θ value	5.27518 (rank : 219)
Query Neighborhood Hits	307	Target Neighborhood Hits	97	Shared Neighborhood Hits	18
SwissProt Accessions	Q70JA7, Q76L22, Q86Y52	Gene names	CSS3, CHSY2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate synthase 3 (EC 2.4.1.175) (Glucuronosyl-N- acetylgalactosaminyl-proteoglycan 4-beta-N- acetylgalactosaminyltransferase II) (Chondroitin synthase 2) (N- acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II) (EC 2.4.1.226) (Chondroitin glucuronyltransferase II) (N- acetylgalactosaminyltransferase II) (Carbohydrate synthase 2).

SLC2B_HUMAN
NC score	0.015084 (rank : 218)	θ value	3.0926 (rank : 190)
Query Neighborhood Hits	307	Target Neighborhood Hits	214	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEV8, Q9Y4D6	Gene names	EXPH5, KIAA0624, SLAC2B
Domain Architecture	No domain graphic available
Description	Slp homolog lacking C2 domains b (Exophilin-5).

LRC41_HUMAN
NC score	0.014972 (rank : 219)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	307	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q15345, Q71RA8, Q9BSM0	Gene names	LRRC41, MUF1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 41 (Protein Muf1).

GNAS1_HUMAN
NC score	0.014548 (rank : 220)	θ value	4.03905 (rank : 199)
Query Neighborhood Hits	307	Target Neighborhood Hits	278	Shared Neighborhood Hits	43
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

TIF1B_HUMAN
NC score	0.014499 (rank : 221)	θ value	0.21417 (rank : 78)
Query Neighborhood Hits	307	Target Neighborhood Hits	312	Shared Neighborhood Hits	21
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

AUXI_HUMAN
NC score	0.014066 (rank : 222)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	307	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	O75061, Q32M66, Q4G0K1, Q5T614, Q5T615	Gene names	DNAJC6, KIAA0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

MYCB_MOUSE
NC score	0.014025 (rank : 223)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	307	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

FRS3_MOUSE
NC score	0.013534 (rank : 224)	θ value	8.99809 (rank : 286)
Query Neighborhood Hits	307	Target Neighborhood Hits	168	Shared Neighborhood Hits	33
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

K0460_HUMAN
NC score	0.013397 (rank : 225)	θ value	8.99809 (rank : 292)
Query Neighborhood Hits	307	Target Neighborhood Hits	357	Shared Neighborhood Hits	26
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LAT3_MOUSE
NC score	0.013388 (rank : 226)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	307	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSM7, Q9D0H7	Gene names	Slc43a1, Lat3
Domain Architecture	No domain graphic available
Description	Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Solute carrier family 43 member 1).

TACC3_HUMAN
NC score	0.013270 (rank : 227)	θ value	3.0926 (rank : 191)
Query Neighborhood Hits	307	Target Neighborhood Hits	779	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

HSF1_HUMAN
NC score	0.013231 (rank : 228)	θ value	8.99809 (rank : 287)
Query Neighborhood Hits	307	Target Neighborhood Hits	163	Shared Neighborhood Hits	20
SwissProt Accessions	Q00613	Gene names	HSF1, HSTF1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

NCA11_MOUSE
NC score	0.013224 (rank : 229)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	307	Target Neighborhood Hits	661	Shared Neighborhood Hits	40
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

UBP43_HUMAN
NC score	0.012984 (rank : 230)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	307	Target Neighborhood Hits	144	Shared Neighborhood Hits	15
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

SIA7A_MOUSE
NC score	0.012815 (rank : 231)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	307	Target Neighborhood Hits	203	Shared Neighborhood Hits	19
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

CSKI1_HUMAN
NC score	0.012545 (rank : 232)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	307	Target Neighborhood Hits	997	Shared Neighborhood Hits	81
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

NEST_HUMAN
NC score	0.012374 (rank : 233)	θ value	3.0926 (rank : 185)
Query Neighborhood Hits	307	Target Neighborhood Hits	1305	Shared Neighborhood Hits	78
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

LDB3_HUMAN
NC score	0.012323 (rank : 234)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	307	Target Neighborhood Hits	497	Shared Neighborhood Hits	39
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

EPN2_HUMAN
NC score	0.012203 (rank : 235)	θ value	8.99809 (rank : 281)
Query Neighborhood Hits	307	Target Neighborhood Hits	156	Shared Neighborhood Hits	21
SwissProt Accessions	O95208, O95207, Q9H7Z2, Q9UPT7	Gene names	EPN2, KIAA1065
Domain Architecture
Description	Epsin-2 (EPS-15-interacting protein 2).

ZFY16_HUMAN
NC score	0.012086 (rank : 236)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	307	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z3T8, O15023, Q7LAU7, Q86T69, Q8N5L3, Q8NEK3	Gene names	ZFYVE16, KIAA0305
Domain Architecture	No domain graphic available
Description	Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome- associated FYVE domain protein).

NHERF_MOUSE
NC score	0.011793 (rank : 237)	θ value	0.813845 (rank : 105)
Query Neighborhood Hits	307	Target Neighborhood Hits	195	Shared Neighborhood Hits	13
SwissProt Accessions	P70441	Gene names	Slc9a3r1, Nherf
Domain Architecture
Description	Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).

FOG1_HUMAN
NC score	0.011666 (rank : 238)	θ value	6.88961 (rank : 254)
Query Neighborhood Hits	307	Target Neighborhood Hits	981	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SREC2_MOUSE
NC score	0.011576 (rank : 239)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	307	Target Neighborhood Hits	605	Shared Neighborhood Hits	33
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

MUC5B_HUMAN
NC score	0.011501 (rank : 240)	θ value	6.88961 (rank : 260)
Query Neighborhood Hits	307	Target Neighborhood Hits	1020	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

DVL2_MOUSE
NC score	0.010958 (rank : 241)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	307	Target Neighborhood Hits	233	Shared Neighborhood Hits	24
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

ZN541_HUMAN
NC score	0.010863 (rank : 242)	θ value	6.88961 (rank : 270)
Query Neighborhood Hits	307	Target Neighborhood Hits	203	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H0D2, Q8NDK8	Gene names	ZNF541
Domain Architecture	No domain graphic available
Description	Zinc finger protein 541.

SH24A_MOUSE
NC score	0.010584 (rank : 243)	θ value	4.03905 (rank : 211)
Query Neighborhood Hits	307	Target Neighborhood Hits	326	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

ZC11A_HUMAN
NC score	0.010574 (rank : 244)	θ value	6.88961 (rank : 266)
Query Neighborhood Hits	307	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

PAR6G_HUMAN
NC score	0.010471 (rank : 245)	θ value	4.03905 (rank : 207)
Query Neighborhood Hits	307	Target Neighborhood Hits	159	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BYG4	Gene names	PARD6G, PAR6G
Domain Architecture
Description	Partitioning defective 6 homolog gamma (PAR-6 gamma) (PAR6D).

AF10_HUMAN
NC score	0.010422 (rank : 246)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	307	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

DCE2_HUMAN
NC score	0.010262 (rank : 247)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	307	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q05329, Q9UD87	Gene names	GAD2, GAD65
Domain Architecture
Description	Glutamate decarboxylase 2 (EC 4.1.1.15) (Glutamate decarboxylase 65 kDa isoform) (GAD-65) (65 kDa glutamic acid decarboxylase).

BAT4_HUMAN
NC score	0.009858 (rank : 248)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	307	Target Neighborhood Hits	157	Shared Neighborhood Hits	4
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

DVL2_HUMAN
NC score	0.009771 (rank : 249)	θ value	5.27518 (rank : 222)
Query Neighborhood Hits	307	Target Neighborhood Hits	223	Shared Neighborhood Hits	21
SwissProt Accessions	O14641	Gene names	DVL2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

DOCK4_MOUSE
NC score	0.009707 (rank : 250)	θ value	5.27518 (rank : 221)
Query Neighborhood Hits	307	Target Neighborhood Hits	210	Shared Neighborhood Hits	25
SwissProt Accessions	P59764	Gene names	Dock4, Kiaa0716
Domain Architecture
Description	Dedicator of cytokinesis protein 4.

MAGD4_HUMAN
NC score	0.009472 (rank : 251)	θ value	5.27518 (rank : 229)
Query Neighborhood Hits	307	Target Neighborhood Hits	338	Shared Neighborhood Hits	44
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

JIP4_HUMAN
NC score	0.009318 (rank : 252)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	307	Target Neighborhood Hits	585	Shared Neighborhood Hits	23
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

TXLNA_HUMAN
NC score	0.009201 (rank : 253)	θ value	5.27518 (rank : 240)
Query Neighborhood Hits	307	Target Neighborhood Hits	982	Shared Neighborhood Hits	63
SwissProt Accessions	P40222, Q66K62, Q86T54, Q86T85, Q86T86, Q86Y86, Q86YW3, Q8N2Y3	Gene names	TXLNA, TXLN
Domain Architecture	No domain graphic available
Description	Alpha-taxilin.

FRS3_HUMAN
NC score	0.009187 (rank : 254)	θ value	8.99809 (rank : 285)
Query Neighborhood Hits	307	Target Neighborhood Hits	76	Shared Neighborhood Hits	9
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

ZFY28_HUMAN
NC score	0.009112 (rank : 255)	θ value	5.27518 (rank : 242)
Query Neighborhood Hits	307	Target Neighborhood Hits	152	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HCC9	Gene names	ZFYVE28, KIAA1643
Domain Architecture
Description	Zinc finger FYVE domain-containing protein 28.

DCP1B_HUMAN
NC score	0.009050 (rank : 256)	θ value	8.99809 (rank : 279)
Query Neighborhood Hits	307	Target Neighborhood Hits	118	Shared Neighborhood Hits	20
SwissProt Accessions	Q8IZD4, Q86XH9, Q96BP8, Q96MZ8	Gene names	DCP1B
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1B (EC 3.-.-.-).

PRDM8_HUMAN
NC score	0.008208 (rank : 257)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	307	Target Neighborhood Hits	591	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NQV8, Q6IQ36	Gene names	PRDM8, PFM5
Domain Architecture	No domain graphic available
Description	PR domain zinc finger protein 8 (PR domain-containing protein 8).

INVS_MOUSE
NC score	0.008051 (rank : 258)	θ value	3.0926 (rank : 178)
Query Neighborhood Hits	307	Target Neighborhood Hits	609	Shared Neighborhood Hits	44
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

AATK_HUMAN
NC score	0.007897 (rank : 259)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	307	Target Neighborhood Hits	1243	Shared Neighborhood Hits	86
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

NU133_MOUSE
NC score	0.007888 (rank : 260)	θ value	5.27518 (rank : 233)
Query Neighborhood Hits	307	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R0G9	Gene names	Nup133
Domain Architecture
Description	Nuclear pore complex protein Nup133 (Nucleoporin Nup133) (133 kDa nucleoporin).

JIP4_MOUSE
NC score	0.007863 (rank : 261)	θ value	6.88961 (rank : 257)
Query Neighborhood Hits	307	Target Neighborhood Hits	593	Shared Neighborhood Hits	22
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

LAP4_HUMAN
NC score	0.007229 (rank : 262)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	307	Target Neighborhood Hits	608	Shared Neighborhood Hits	33
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

AATK_MOUSE
NC score	0.007201 (rank : 263)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	307	Target Neighborhood Hits	942	Shared Neighborhood Hits	54
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

NDF6_MOUSE
NC score	0.007171 (rank : 264)	θ value	3.0926 (rank : 184)
Query Neighborhood Hits	307	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

MYCB2_MOUSE
NC score	0.007039 (rank : 265)	θ value	8.99809 (rank : 297)
Query Neighborhood Hits	307	Target Neighborhood Hits	307	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

STAR8_HUMAN
NC score	0.007011 (rank : 266)	θ value	6.88961 (rank : 264)
Query Neighborhood Hits	307	Target Neighborhood Hits	216	Shared Neighborhood Hits	21
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

SPEG_HUMAN
NC score	0.006960 (rank : 267)	θ value	5.27518 (rank : 236)
Query Neighborhood Hits	307	Target Neighborhood Hits	1762	Shared Neighborhood Hits	102
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

KBTBB_HUMAN
NC score	0.006677 (rank : 268)	θ value	3.0926 (rank : 179)
Query Neighborhood Hits	307	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	O94819	Gene names	KBTBD11, KIAA0711, KLHDC7C
Domain Architecture	No domain graphic available
Description	Kelch repeat and BTB domain-containing protein 11 (Kelch domain- containing protein 7B).

ZFHX2_HUMAN
NC score	0.006564 (rank : 269)	θ value	5.27518 (rank : 241)
Query Neighborhood Hits	307	Target Neighborhood Hits	1178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

GP124_MOUSE
NC score	0.006453 (rank : 270)	θ value	0.62314 (rank : 97)
Query Neighborhood Hits	307	Target Neighborhood Hits	423	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

NDF6_HUMAN
NC score	0.006166 (rank : 271)	θ value	5.27518 (rank : 232)
Query Neighborhood Hits	307	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

RREB1_HUMAN
NC score	0.005883 (rank : 272)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	307	Target Neighborhood Hits	879	Shared Neighborhood Hits	41
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

ZN516_MOUSE
NC score	0.005587 (rank : 273)	θ value	6.88961 (rank : 269)
Query Neighborhood Hits	307	Target Neighborhood Hits	1197	Shared Neighborhood Hits	86
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

CUTL1_MOUSE
NC score	0.005399 (rank : 274)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	307	Target Neighborhood Hits	1620	Shared Neighborhood Hits	65
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

JHD2B_MOUSE
NC score	0.005294 (rank : 275)	θ value	8.99809 (rank : 291)
Query Neighborhood Hits	307	Target Neighborhood Hits	115	Shared Neighborhood Hits	9
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

PCSK7_MOUSE
NC score	0.005101 (rank : 276)	θ value	3.0926 (rank : 186)
Query Neighborhood Hits	307	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q61139, O08577	Gene names	Pcsk7, Pc7
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 7 precursor (EC 3.4.21.-) (Proprotein convertase PC7) (Subtilisin/kexin-like protease PC7) (Prohormone convertase PC7) (Subtilisin-like proprotein convertase 7) (SPC7).

STIM2_HUMAN
NC score	0.004983 (rank : 277)	θ value	5.27518 (rank : 238)
Query Neighborhood Hits	307	Target Neighborhood Hits	420	Shared Neighborhood Hits	13
SwissProt Accessions	Q9P246, Q96BF1, Q9BQH2, Q9H8R1	Gene names	STIM2, KIAA1482
Domain Architecture
Description	Stromal interaction molecule 2 precursor.

LIPA3_MOUSE
NC score	0.004771 (rank : 278)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	307	Target Neighborhood Hits	636	Shared Neighborhood Hits	18
SwissProt Accessions	P60469	Gene names	Ppfia3
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

ARSI_HUMAN
NC score	0.004576 (rank : 279)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	307	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q5FYB1	Gene names	ARSI
Domain Architecture	No domain graphic available
Description	Arylsulfatase I precursor (EC 3.1.6.-) (ASI).

INVS_HUMAN
NC score	0.004565 (rank : 280)	θ value	3.0926 (rank : 177)
Query Neighborhood Hits	307	Target Neighborhood Hits	455	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

PLCB3_HUMAN
NC score	0.004315 (rank : 281)	θ value	4.03905 (rank : 208)
Query Neighborhood Hits	307	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q01970	Gene names	PLCB3
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 3 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-3) (PLC-beta-3).

ZDHC1_HUMAN
NC score	0.004092 (rank : 282)	θ value	6.88961 (rank : 268)
Query Neighborhood Hits	307	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WTX9, O15461	Gene names	ZDHHC1, C16orf1, ZNF377
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC1 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 1) (DHHC-1) (Zinc finger protein 377) (DHHC- domain-containing cysteine-rich protein 1).

DSCL1_HUMAN
NC score	0.004083 (rank : 283)	θ value	4.03905 (rank : 197)
Query Neighborhood Hits	307	Target Neighborhood Hits	589	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

SOX30_MOUSE
NC score	0.003946 (rank : 284)	θ value	8.99809 (rank : 302)
Query Neighborhood Hits	307	Target Neighborhood Hits	374	Shared Neighborhood Hits	25
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

TITIN_HUMAN
NC score	0.003804 (rank : 285)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	307	Target Neighborhood Hits	2923	Shared Neighborhood Hits	87
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

BNIPL_HUMAN
NC score	0.003773 (rank : 286)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	307	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

ADA12_MOUSE
NC score	0.003625 (rank : 287)	θ value	6.88961 (rank : 244)
Query Neighborhood Hits	307	Target Neighborhood Hits	474	Shared Neighborhood Hits	37
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

SALL3_HUMAN
NC score	0.003569 (rank : 288)	θ value	6.88961 (rank : 261)
Query Neighborhood Hits	307	Target Neighborhood Hits	1066	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

RPA1_HUMAN
NC score	0.003436 (rank : 289)	θ value	8.99809 (rank : 301)
Query Neighborhood Hits	307	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	O95602, Q9UEH0, Q9UFT9	Gene names	POLR1A
Domain Architecture
Description	DNA-directed RNA polymerase I largest subunit (EC 2.7.7.6) (RNA polymerase I 194 kDa subunit) (RPA194).

CLCN7_MOUSE
NC score	0.003288 (rank : 290)	θ value	6.88961 (rank : 247)
Query Neighborhood Hits	307	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	O70496	Gene names	Clcn7, Clc7
Domain Architecture
Description	Chloride channel protein 7 (ClC-7).

BFSP1_HUMAN
NC score	0.003152 (rank : 291)	θ value	5.27518 (rank : 218)
Query Neighborhood Hits	307	Target Neighborhood Hits	508	Shared Neighborhood Hits	13
SwissProt Accessions	Q12934, O43595, O76034, Q9HBX4	Gene names	BFSP1
Domain Architecture
Description	Filensin (Beaded filament structural protein 1) (Lens fiber cell beaded-filament structural protein CP 115) (CP115) (Lens intermediate filament-like heavy) (LIFL-H).

HXK4_HUMAN
NC score	0.002865 (rank : 292)	θ value	8.99809 (rank : 289)
Query Neighborhood Hits	307	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P35557, Q05810	Gene names	GCK
Domain Architecture
Description	Glucokinase (EC 2.7.1.2) (Hexokinase-4) (Hexokinase type IV) (HK IV) (HK4) (Hexokinase-D).

DZIP1_HUMAN
NC score	0.002785 (rank : 293)	θ value	8.99809 (rank : 280)
Query Neighborhood Hits	307	Target Neighborhood Hits	675	Shared Neighborhood Hits	15
SwissProt Accessions	Q86YF9, Q8WY45, Q8WY46, Q9UGA5, Q9Y2K0	Gene names	DZIP1, DZIP, DZIP2, KIAA0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1/2).

MAST1_MOUSE
NC score	0.002750 (rank : 294)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	307	Target Neighborhood Hits	1123	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

IRAK1_HUMAN
NC score	0.002583 (rank : 295)	θ value	4.03905 (rank : 200)
Query Neighborhood Hits	307	Target Neighborhood Hits	820	Shared Neighborhood Hits	30
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

KIRR2_HUMAN
NC score	0.002480 (rank : 296)	θ value	8.99809 (rank : 294)
Query Neighborhood Hits	307	Target Neighborhood Hits	321	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

CSPG3_HUMAN
NC score	0.002479 (rank : 297)	θ value	5.27518 (rank : 220)
Query Neighborhood Hits	307	Target Neighborhood Hits	676	Shared Neighborhood Hits	40
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ETV5_HUMAN
NC score	0.002322 (rank : 298)	θ value	8.99809 (rank : 282)
Query Neighborhood Hits	307	Target Neighborhood Hits	181	Shared Neighborhood Hits	12
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

MAST1_HUMAN
NC score	0.002197 (rank : 299)	θ value	3.0926 (rank : 183)
Query Neighborhood Hits	307	Target Neighborhood Hits	1146	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

TAF5_HUMAN
NC score	0.001613 (rank : 300)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	307	Target Neighborhood Hits	352	Shared Neighborhood Hits	8
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

FREA_MOUSE
NC score	0.001598 (rank : 301)	θ value	8.99809 (rank : 284)
Query Neighborhood Hits	307	Target Neighborhood Hits	147	Shared Neighborhood Hits	16
SwissProt Accessions	Q61574, Q8C5N7	Gene names	Fkhl18, Fkh3, Freac10
Domain Architecture	No domain graphic available
Description	Forkhead-related transcription factor 10 (FREAC-10) (Forkhead-like 18 protein) (Transcription factor FKH-3).

ATBF1_HUMAN
NC score	0.001403 (rank : 302)	θ value	6.88961 (rank : 245)
Query Neighborhood Hits	307	Target Neighborhood Hits	1547	Shared Neighborhood Hits	60
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

M3K15_HUMAN
NC score	0.001273 (rank : 303)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	307	Target Neighborhood Hits	914	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZN16, Q5JPR4, Q6ZMV3	Gene names	MAP3K15
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 15 (EC 2.7.11.25) (MAPK/ERK kinase kinase 15) (MEK kinase 15) (MEKK 15).

MAST2_MOUSE
NC score	0.001131 (rank : 304)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	307	Target Neighborhood Hits	1110	Shared Neighborhood Hits	46
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

HIC1_HUMAN
NC score	0.001057 (rank : 305)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	307	Target Neighborhood Hits	838	Shared Neighborhood Hits	30
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

HME2_HUMAN
NC score	0.000912 (rank : 306)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	307	Target Neighborhood Hits	355	Shared Neighborhood Hits	9
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

MYLK2_HUMAN
NC score	0.000691 (rank : 307)	θ value	5.27518 (rank : 231)
Query Neighborhood Hits	307	Target Neighborhood Hits	920	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

TRI47_HUMAN
NC score	0.000554 (rank : 308)	θ value	8.99809 (rank : 304)
Query Neighborhood Hits	307	Target Neighborhood Hits	286	Shared Neighborhood Hits	4
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

FOXE3_HUMAN
NC score	0.000402 (rank : 309)	θ value	8.99809 (rank : 283)
Query Neighborhood Hits	307	Target Neighborhood Hits	112	Shared Neighborhood Hits	8
SwissProt Accessions	Q13461, Q5SVY9, Q9NQV9	Gene names	FOXE3, FKHL12, FREAC8
Domain Architecture
Description	Forkhead box protein E3 (Forkhead-related protein FKHL12) (Forkhead- related transcription factor 8) (FREAC-8).

GOGA3_HUMAN
NC score	0.000210 (rank : 310)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	307	Target Neighborhood Hits	1317	Shared Neighborhood Hits	35
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

IRAK1_MOUSE
NC score	-0.000095 (rank : 311)	θ value	4.03905 (rank : 201)
Query Neighborhood Hits	307	Target Neighborhood Hits	784	Shared Neighborhood Hits	22
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

RPKL1_HUMAN
NC score	-0.000148 (rank : 312)	θ value	5.27518 (rank : 234)
Query Neighborhood Hits	307	Target Neighborhood Hits	708	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

TAF5_MOUSE
NC score	-0.000380 (rank : 313)	θ value	8.99809 (rank : 303)
Query Neighborhood Hits	307	Target Neighborhood Hits	366	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

HXD11_MOUSE
NC score	-0.000642 (rank : 314)	θ value	8.99809 (rank : 288)
Query Neighborhood Hits	307	Target Neighborhood Hits	376	Shared Neighborhood Hits	16
SwissProt Accessions	P23813	Gene names	Hoxd11, Hox-4.6, Hoxd-11
Domain Architecture
Description	Homeobox protein Hox-D11 (Hox-4.6) (Hox-5.5).

HXA2_HUMAN
NC score	-0.000713 (rank : 315)	θ value	6.88961 (rank : 255)
Query Neighborhood Hits	307	Target Neighborhood Hits	370	Shared Neighborhood Hits	19
SwissProt Accessions	O43364	Gene names	HOXA2
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-A2.

5HT6R_MOUSE
NC score	-0.000807 (rank : 316)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	307	Target Neighborhood Hits	881	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R1C8	Gene names	Htr6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

5HT6R_HUMAN
NC score	-0.000873 (rank : 317)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	307	Target Neighborhood Hits	882	Shared Neighborhood Hits	4
SwissProt Accessions	P50406, Q13640	Gene names	HTR6
Domain Architecture
Description	5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6).

MARK4_MOUSE
NC score	-0.000945 (rank : 318)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	307	Target Neighborhood Hits	898	Shared Neighborhood Hits	27
SwissProt Accessions	Q8CIP4, Q80T81	Gene names	Mark4, Kiaa1860
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1).

ZBT10_HUMAN
NC score	-0.001078 (rank : 319)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	307	Target Neighborhood Hits	831	Shared Neighborhood Hits	15
SwissProt Accessions	Q96DT7, Q86W96, Q8IXI9, Q96MH9	Gene names	ZBTB10, RINZF, RINZFC
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 10 (Zinc finger protein RIN ZF).

M3K14_HUMAN
NC score	-0.001229 (rank : 320)	θ value	4.03905 (rank : 205)
Query Neighborhood Hits	307	Target Neighborhood Hits	887	Shared Neighborhood Hits	28
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

KCC2B_HUMAN
NC score	-0.001336 (rank : 321)	θ value	5.27518 (rank : 227)
Query Neighborhood Hits	307	Target Neighborhood Hits	866	Shared Neighborhood Hits	26
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

FGFR1_HUMAN
NC score	-0.002577 (rank : 322)	θ value	5.27518 (rank : 224)
Query Neighborhood Hits	307	Target Neighborhood Hits	1069	Shared Neighborhood Hits	22
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

ZIC2_MOUSE
NC score	-0.002619 (rank : 323)	θ value	1.81305 (rank : 146)
Query Neighborhood Hits	307	Target Neighborhood Hits	727	Shared Neighborhood Hits	15
SwissProt Accessions	Q62520	Gene names	Zic2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2).

FGFR1_MOUSE
NC score	-0.002671 (rank : 324)	θ value	6.88961 (rank : 253)
Query Neighborhood Hits	307	Target Neighborhood Hits	1068	Shared Neighborhood Hits	22
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

EGR1_HUMAN
NC score	-0.002992 (rank : 325)	θ value	4.03905 (rank : 198)
Query Neighborhood Hits	307	Target Neighborhood Hits	788	Shared Neighborhood Hits	21
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

ZNF71_HUMAN
NC score	-0.004339 (rank : 326)	θ value	2.36792 (rank : 167)
Query Neighborhood Hits	307	Target Neighborhood Hits	764	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQZ8, Q15919, Q9UC09, Q9UQD3	Gene names	ZNF71, EZFIT
Domain Architecture
Description	Endothelial zinc finger protein induced by tumor necrosis factor alpha (Zinc finger protein 71) (ZNF47).

ZN497_HUMAN
NC score	-0.004619 (rank : 327)	θ value	5.27518 (rank : 243)
Query Neighborhood Hits	307	Target Neighborhood Hits	748	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZNH5, Q6ZTD2, Q9UIA8	Gene names	ZNF497
Domain Architecture	No domain graphic available
Description	Zinc finger protein 497.