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Network neighborhood for query Sequence : CAC1C_HUMAN

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CAC1C_HUMAN
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAC1A_HUMAN
θ value	0 (rank : 1)	NC score	0.943432 (rank : 13)
Query Neighborhood Hits	158	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	0 (rank : 2)	NC score	0.952074 (rank : 11)
Query Neighborhood Hits	158	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	0 (rank : 3)	NC score	0.953187 (rank : 10)
Query Neighborhood Hits	158	Target Neighborhood Hits	257	Shared Neighborhood Hits	59
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	0 (rank : 4)	NC score	0.947621 (rank : 12)
Query Neighborhood Hits	158	Target Neighborhood Hits	351	Shared Neighborhood Hits	58
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	158
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
θ value	0 (rank : 6)	NC score	0.997417 (rank : 2)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	97
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	0 (rank : 7)	NC score	0.993159 (rank : 4)
Query Neighborhood Hits	158	Target Neighborhood Hits	118	Shared Neighborhood Hits	59
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	0 (rank : 8)	NC score	0.956906 (rank : 9)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	57
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	0 (rank : 9)	NC score	0.956957 (rank : 8)
Query Neighborhood Hits	158	Target Neighborhood Hits	167	Shared Neighborhood Hits	56
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	0 (rank : 10)	NC score	0.991536 (rank : 7)
Query Neighborhood Hits	158	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	0 (rank : 11)	NC score	0.991921 (rank : 6)
Query Neighborhood Hits	158	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1S_HUMAN
θ value	0 (rank : 12)	NC score	0.993726 (rank : 3)
Query Neighborhood Hits	158	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_MOUSE
θ value	0 (rank : 13)	NC score	0.993102 (rank : 5)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN7A_HUMAN
θ value	1.88829e-90 (rank : 14)	NC score	0.848490 (rank : 19)
Query Neighborhood Hits	158	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SC11A_MOUSE
θ value	1.2268e-81 (rank : 15)	NC score	0.854321 (rank : 17)
Query Neighborhood Hits	158	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1I_HUMAN
θ value	7.71989e-68 (rank : 16)	NC score	0.888878 (rank : 14)
Query Neighborhood Hits	158	Target Neighborhood Hits	138	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_HUMAN
θ value	1.90147e-66 (rank : 17)	NC score	0.851551 (rank : 18)
Query Neighborhood Hits	158	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN3A_HUMAN
θ value	6.11685e-65 (rank : 18)	NC score	0.836907 (rank : 23)
Query Neighborhood Hits	158	Target Neighborhood Hits	115	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN2A_HUMAN
θ value	7.98882e-65 (rank : 19)	NC score	0.834164 (rank : 25)
Query Neighborhood Hits	158	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
θ value	1.04338e-64 (rank : 20)	NC score	0.833834 (rank : 26)
Query Neighborhood Hits	158	Target Neighborhood Hits	157	Shared Neighborhood Hits	60
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN4A_HUMAN
θ value	1.77973e-64 (rank : 21)	NC score	0.844145 (rank : 22)
Query Neighborhood Hits	158	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN1A_HUMAN
θ value	5.92465e-60 (rank : 22)	NC score	0.831669 (rank : 28)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN8A_HUMAN
θ value	6.55044e-59 (rank : 23)	NC score	0.832798 (rank : 27)
Query Neighborhood Hits	158	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	1.45929e-58 (rank : 24)	NC score	0.830152 (rank : 30)
Query Neighborhood Hits	158	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1H_HUMAN
θ value	1.90589e-58 (rank : 25)	NC score	0.859437 (rank : 16)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC10A_HUMAN
θ value	2.48917e-58 (rank : 26)	NC score	0.830420 (rank : 29)
Query Neighborhood Hits	158	Target Neighborhood Hits	116	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN5A_HUMAN
θ value	2.48917e-58 (rank : 27)	NC score	0.845448 (rank : 20)
Query Neighborhood Hits	158	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SC10A_MOUSE
θ value	3.25095e-58 (rank : 28)	NC score	0.834721 (rank : 24)
Query Neighborhood Hits	158	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1G_HUMAN
θ value	4.24587e-58 (rank : 29)	NC score	0.844169 (rank : 21)
Query Neighborhood Hits	158	Target Neighborhood Hits	587	Shared Neighborhood Hits	59
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1H_MOUSE
θ value	7.24236e-58 (rank : 30)	NC score	0.862526 (rank : 15)
Query Neighborhood Hits	158	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

PK2L2_HUMAN
θ value	2.36244e-08 (rank : 31)	NC score	0.389723 (rank : 31)
Query Neighborhood Hits	158	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_HUMAN
θ value	8.97725e-08 (rank : 32)	NC score	0.336289 (rank : 35)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

PK2L2_MOUSE
θ value	1.53129e-07 (rank : 33)	NC score	0.353315 (rank : 33)
Query Neighborhood Hits	158	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
θ value	2.88788e-06 (rank : 34)	NC score	0.355677 (rank : 32)
Query Neighborhood Hits	158	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

KCNF1_HUMAN
θ value	1.87187e-05 (rank : 35)	NC score	0.237582 (rank : 36)
Query Neighborhood Hits	158	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

PKD2_MOUSE
θ value	2.44474e-05 (rank : 36)	NC score	0.341152 (rank : 34)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

KCNB2_HUMAN
θ value	0.00102713 (rank : 37)	NC score	0.206996 (rank : 38)
Query Neighborhood Hits	158	Target Neighborhood Hits	212	Shared Neighborhood Hits	59
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNB1_HUMAN
θ value	0.00134147 (rank : 38)	NC score	0.194333 (rank : 42)
Query Neighborhood Hits	158	Target Neighborhood Hits	169	Shared Neighborhood Hits	57
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	0.00134147 (rank : 39)	NC score	0.194443 (rank : 41)
Query Neighborhood Hits	158	Target Neighborhood Hits	154	Shared Neighborhood Hits	58
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNS3_HUMAN
θ value	0.00134147 (rank : 40)	NC score	0.173293 (rank : 45)
Query Neighborhood Hits	158	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND1_MOUSE
θ value	0.00509761 (rank : 41)	NC score	0.160734 (rank : 48)
Query Neighborhood Hits	158	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNS2_HUMAN
θ value	0.0113563 (rank : 42)	NC score	0.195064 (rank : 40)
Query Neighborhood Hits	158	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS1_MOUSE
θ value	0.0193708 (rank : 43)	NC score	0.136162 (rank : 51)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	49
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCND3_HUMAN
θ value	0.0252991 (rank : 44)	NC score	0.176208 (rank : 44)
Query Neighborhood Hits	158	Target Neighborhood Hits	162	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.0252991 (rank : 45)	NC score	0.176363 (rank : 43)
Query Neighborhood Hits	158	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNQ4_HUMAN
θ value	0.0252991 (rank : 46)	NC score	0.096294 (rank : 62)
Query Neighborhood Hits	158	Target Neighborhood Hits	136	Shared Neighborhood Hits	38
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ2_MOUSE
θ value	0.0330416 (rank : 47)	NC score	0.064952 (rank : 79)
Query Neighborhood Hits	158	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNS2_MOUSE
θ value	0.0330416 (rank : 48)	NC score	0.198476 (rank : 39)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNV2_HUMAN
θ value	0.0330416 (rank : 49)	NC score	0.223221 (rank : 37)
Query Neighborhood Hits	158	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCND1_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.156378 (rank : 49)
Query Neighborhood Hits	158	Target Neighborhood Hits	160	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.169766 (rank : 47)
Query Neighborhood Hits	158	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.0431538 (rank : 52)	NC score	0.169915 (rank : 46)
Query Neighborhood Hits	158	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNQ2_HUMAN
θ value	0.0431538 (rank : 53)	NC score	0.068769 (rank : 75)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNS1_HUMAN
θ value	0.0431538 (rank : 54)	NC score	0.146699 (rank : 50)
Query Neighborhood Hits	158	Target Neighborhood Hits	116	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

SELPL_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.014411 (rank : 112)
Query Neighborhood Hits	158	Target Neighborhood Hits	588	Shared Neighborhood Hits	11
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RILP_HUMAN
θ value	0.125558 (rank : 56)	NC score	0.034011 (rank : 91)
Query Neighborhood Hits	158	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

NIPBL_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.033805 (rank : 92)
Query Neighborhood Hits	158	Target Neighborhood Hits	1311	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TP53B_MOUSE
θ value	0.279714 (rank : 58)	NC score	0.024042 (rank : 99)
Query Neighborhood Hits	158	Target Neighborhood Hits	644	Shared Neighborhood Hits	25
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

IWS1_MOUSE
θ value	0.47712 (rank : 59)	NC score	0.035299 (rank : 90)
Query Neighborhood Hits	158	Target Neighborhood Hits	1258	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

REL_MOUSE
θ value	0.47712 (rank : 60)	NC score	0.010631 (rank : 120)
Query Neighborhood Hits	158	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

SF3B1_HUMAN
θ value	0.47712 (rank : 61)	NC score	0.026677 (rank : 96)
Query Neighborhood Hits	158	Target Neighborhood Hits	341	Shared Neighborhood Hits	10
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	0.47712 (rank : 62)	NC score	0.026715 (rank : 95)
Query Neighborhood Hits	158	Target Neighborhood Hits	352	Shared Neighborhood Hits	10
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TPTE2_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.130599 (rank : 52)
Query Neighborhood Hits	158	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

ADDB_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.013852 (rank : 113)
Query Neighborhood Hits	158	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

DJBP_MOUSE
θ value	1.06291 (rank : 65)	NC score	0.057734 (rank : 86)
Query Neighborhood Hits	158	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

IWS1_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.019427 (rank : 102)
Query Neighborhood Hits	158	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MB3L2_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.017372 (rank : 104)
Query Neighborhood Hits	158	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

SEN34_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.021782 (rank : 100)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

ADDB_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.012371 (rank : 119)
Query Neighborhood Hits	158	Target Neighborhood Hits	574	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

APLP2_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.013382 (rank : 115)
Query Neighborhood Hits	158	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

CXA12_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.004858 (rank : 149)
Query Neighborhood Hits	158	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQU6, Q6TLV2, Q8BQS2, Q9EPM1	Gene names	Gja12
Domain Architecture	No domain graphic available
Description	Gap junction alpha-12 protein (Connexin-47) (Cx47).

FSCN1_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.015424 (rank : 107)
Query Neighborhood Hits	158	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

FSCN1_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.015542 (rank : 106)
Query Neighborhood Hits	158	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q61553, O09099, O09156	Gene names	Fscn1, Fan1, Snl
Domain Architecture
Description	Fascin (Singed-like protein).

ZFP13_MOUSE
θ value	1.38821 (rank : 74)	NC score	-0.004531 (rank : 182)
Query Neighborhood Hits	158	Target Neighborhood Hits	771	Shared Neighborhood Hits	6
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).

ANX11_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.004932 (rank : 146)
Query Neighborhood Hits	158	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

EHMT2_HUMAN
θ value	1.81305 (rank : 76)	NC score	0.001930 (rank : 167)
Query Neighborhood Hits	158	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

KCNG2_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.070328 (rank : 72)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNH4_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.007181 (rank : 132)
Query Neighborhood Hits	158	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNQ1_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.081093 (rank : 64)
Query Neighborhood Hits	158	Target Neighborhood Hits	175	Shared Neighborhood Hits	37
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

POT15_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.005558 (rank : 141)
Query Neighborhood Hits	158	Target Neighborhood Hits	893	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TENA_MOUSE
θ value	1.81305 (rank : 81)	NC score	0.000427 (rank : 176)
Query Neighborhood Hits	158	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TUR8_MOUSE
θ value	1.81305 (rank : 82)	NC score	0.028404 (rank : 94)
Query Neighborhood Hits	158	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

ANR21_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.005354 (rank : 143)
Query Neighborhood Hits	158	Target Neighborhood Hits	864	Shared Neighborhood Hits	23
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

AXN1_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.007143 (rank : 133)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

BSCL2_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.024496 (rank : 98)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

NASP_HUMAN
θ value	2.36792 (rank : 86)	NC score	0.018979 (rank : 103)
Query Neighborhood Hits	158	Target Neighborhood Hits	709	Shared Neighborhood Hits	28
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ACINU_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.014551 (rank : 111)
Query Neighborhood Hits	158	Target Neighborhood Hits	828	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AKAP9_HUMAN
θ value	3.0926 (rank : 88)	NC score	-0.001550 (rank : 178)
Query Neighborhood Hits	158	Target Neighborhood Hits	1710	Shared Neighborhood Hits	23
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CSTN1_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.004913 (rank : 147)
Query Neighborhood Hits	158	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

FANCJ_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.007314 (rank : 131)
Query Neighborhood Hits	158	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

GATA4_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.005308 (rank : 144)
Query Neighborhood Hits	158	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q08369, P97491, Q9QZK4	Gene names	Gata4, Gata-4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

RGS3_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.015385 (rank : 108)
Query Neighborhood Hits	158	Target Neighborhood Hits	1621	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AKA12_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.015329 (rank : 109)
Query Neighborhood Hits	158	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

APHC_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.009186 (rank : 124)
Query Neighborhood Hits	158	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUN7	Gene names	PHCA, APHC
Domain Architecture
Description	Alkaline phytoceramidase (EC 3.5.1.-) (aPHC) (Alkaline ceramidase) (Alkaline dihydroceramidase SB89).

AT132_MOUSE
θ value	4.03905 (rank : 95)	NC score	0.003475 (rank : 159)
Query Neighborhood Hits	158	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CTG6, Q8CG98	Gene names	Atp13a2
Domain Architecture	No domain graphic available
Description	Probable cation-transporting ATPase 13A2 (EC 3.6.3.-).

CD20_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.008252 (rank : 128)
Query Neighborhood Hits	158	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P11836, P08984, Q13963	Gene names	MS4A1, CD20
Domain Architecture
Description	B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Leu-16) (Bp35).

KCNA6_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.076416 (rank : 68)
Query Neighborhood Hits	158	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNC4_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.120058 (rank : 55)
Query Neighborhood Hits	158	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

LEO1_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.013028 (rank : 116)
Query Neighborhood Hits	158	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MLL3_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.004243 (rank : 151)
Query Neighborhood Hits	158	Target Neighborhood Hits	1644	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYPN_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.003952 (rank : 153)
Query Neighborhood Hits	158	Target Neighborhood Hits	421	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

OR4B1_HUMAN
θ value	4.03905 (rank : 102)	NC score	-0.004195 (rank : 179)
Query Neighborhood Hits	158	Target Neighborhood Hits	652	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NGF8, Q6IF75, Q96R64	Gene names	OR4B1
Domain Architecture
Description	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106).

RNPC1_MOUSE
θ value	4.03905 (rank : 103)	NC score	0.003128 (rank : 162)
Query Neighborhood Hits	158	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

SMC3_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.003715 (rank : 155)
Query Neighborhood Hits	158	Target Neighborhood Hits	1186	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.003675 (rank : 157)
Query Neighborhood Hits	158	Target Neighborhood Hits	1187	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

TPR_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.001082 (rank : 173)
Query Neighborhood Hits	158	Target Neighborhood Hits	1921	Shared Neighborhood Hits	37
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TPTE_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.091427 (rank : 63)
Query Neighborhood Hits	158	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

ANX11_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.003668 (rank : 158)
Query Neighborhood Hits	158	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

DNL3_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.028612 (rank : 93)
Query Neighborhood Hits	158	Target Neighborhood Hits	49	Shared Neighborhood Hits	9
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

KCNQ1_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.068252 (rank : 76)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

MAP1B_MOUSE
θ value	5.27518 (rank : 111)	NC score	0.008738 (rank : 125)
Query Neighborhood Hits	158	Target Neighborhood Hits	977	Shared Neighborhood Hits	33
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PCX3_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.012770 (rank : 117)
Query Neighborhood Hits	158	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

RGS3_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.004047 (rank : 152)
Query Neighborhood Hits	158	Target Neighborhood Hits	1375	Shared Neighborhood Hits	21
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

APLP1_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.006666 (rank : 135)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

BUB1B_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.012728 (rank : 118)
Query Neighborhood Hits	158	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

CALD1_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.002484 (rank : 164)
Query Neighborhood Hits	158	Target Neighborhood Hits	959	Shared Neighborhood Hits	25
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CALX_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.005978 (rank : 140)
Query Neighborhood Hits	158	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

CDA7L_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.006077 (rank : 139)
Query Neighborhood Hits	158	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

CDR2_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.003250 (rank : 161)
Query Neighborhood Hits	158	Target Neighborhood Hits	404	Shared Neighborhood Hits	10
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

DNL3_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.025473 (rank : 97)
Query Neighborhood Hits	158	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

KCNC3_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.107844 (rank : 57)
Query Neighborhood Hits	158	Target Neighborhood Hits	256	Shared Neighborhood Hits	53
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.106282 (rank : 58)
Query Neighborhood Hits	158	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KLC2_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.004896 (rank : 148)
Query Neighborhood Hits	158	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

KLC2_MOUSE
θ value	6.88961 (rank : 124)	NC score	0.004945 (rank : 145)
Query Neighborhood Hits	158	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

LDOC1_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.021643 (rank : 101)
Query Neighborhood Hits	158	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPY9	Gene names	Ldoc1
Domain Architecture	No domain graphic available
Description	Protein LDOC1.

MTMR5_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.002473 (rank : 165)
Query Neighborhood Hits	158	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

MUC1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.006498 (rank : 136)
Query Neighborhood Hits	158	Target Neighborhood Hits	388	Shared Neighborhood Hits	15
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PKDRE_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.101153 (rank : 59)
Query Neighborhood Hits	158	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PROP_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.001055 (rank : 174)
Query Neighborhood Hits	158	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

RBBP6_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.016680 (rank : 105)
Query Neighborhood Hits	158	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

SEN34_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.013556 (rank : 114)
Query Neighborhood Hits	158	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

TXD13_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.008735 (rank : 126)
Query Neighborhood Hits	158	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

AP3B2_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.006820 (rank : 134)
Query Neighborhood Hits	158	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

APBA1_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.006119 (rank : 138)
Query Neighborhood Hits	158	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

B4GN3_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.003306 (rank : 160)
Query Neighborhood Hits	158	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

BAZ2B_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.001003 (rank : 175)
Query Neighborhood Hits	158	Target Neighborhood Hits	803	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BTC_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.008500 (rank : 127)
Query Neighborhood Hits	158	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CALX_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.005486 (rank : 142)
Query Neighborhood Hits	158	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

COFA1_MOUSE
θ value	8.99809 (rank : 139)	NC score	0.002041 (rank : 166)
Query Neighborhood Hits	158	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

CRKL_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.001619 (rank : 170)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	5
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

DGLA_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.010314 (rank : 121)
Query Neighborhood Hits	158	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4D2, Q6WQJ0	Gene names	NSDDR, C11orf11, KIAA0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

DGLA_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.009985 (rank : 122)
Query Neighborhood Hits	158	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

DJBP_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.015071 (rank : 110)
Query Neighborhood Hits	158	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

ES8L3_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.001893 (rank : 168)
Query Neighborhood Hits	158	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

FRG1_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.007574 (rank : 130)
Query Neighborhood Hits	158	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRG1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.007754 (rank : 129)
Query Neighborhood Hits	158	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

JHD1B_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.001861 (rank : 169)
Query Neighborhood Hits	158	Target Neighborhood Hits	214	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

KI21A_MOUSE
θ value	8.99809 (rank : 148)	NC score	-0.000315 (rank : 177)
Query Neighborhood Hits	158	Target Neighborhood Hits	1317	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KLC4_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.003792 (rank : 154)
Query Neighborhood Hits	158	Target Neighborhood Hits	327	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

MAST2_MOUSE
θ value	8.99809 (rank : 150)	NC score	-0.004313 (rank : 181)
Query Neighborhood Hits	158	Target Neighborhood Hits	1110	Shared Neighborhood Hits	11
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MYB_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.002967 (rank : 163)
Query Neighborhood Hits	158	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P06876, Q61929	Gene names	Myb
Domain Architecture
Description	Myb proto-oncogene protein (C-myb).

OR6Y1_HUMAN
θ value	8.99809 (rank : 152)	NC score	-0.004224 (rank : 180)
Query Neighborhood Hits	158	Target Neighborhood Hits	701	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NGX8, Q6IFS0	Gene names	OR6Y1, OR6Y2
Domain Architecture
Description	Olfactory receptor 6Y1 (Olfactory receptor OR1-11).

SH2D3_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.006397 (rank : 137)
Query Neighborhood Hits	158	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

SKIL_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.001442 (rank : 171)
Query Neighborhood Hits	158	Target Neighborhood Hits	460	Shared Neighborhood Hits	13
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

T2R16_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.001294 (rank : 172)
Query Neighborhood Hits	158	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYV7, Q502V3, Q549U8, Q645W1	Gene names	TAS2R16
Domain Architecture
Description	Taste receptor type 2 member 16 (T2R16).

TCRG1_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.004301 (rank : 150)
Query Neighborhood Hits	158	Target Neighborhood Hits	929	Shared Neighborhood Hits	26
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TXD13_MOUSE
θ value	8.99809 (rank : 157)	NC score	0.009790 (rank : 123)
Query Neighborhood Hits	158	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

ZC3H8_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.003683 (rank : 156)
Query Neighborhood Hits	158	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

KCNA1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.078183 (rank : 66)
Query Neighborhood Hits	158	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.080231 (rank : 65)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.076410 (rank : 69)
Query Neighborhood Hits	158	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.077419 (rank : 67)
Query Neighborhood Hits	158	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.065308 (rank : 78)
Query Neighborhood Hits	158	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.064439 (rank : 80)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.055160 (rank : 88)
Query Neighborhood Hits	158	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.055437 (rank : 87)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.062798 (rank : 81)
Query Neighborhood Hits	158	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.067406 (rank : 77)
Query Neighborhood Hits	158	Target Neighborhood Hits	119	Shared Neighborhood Hits	37
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA6_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.069600 (rank : 74)
Query Neighborhood Hits	158	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNC1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.124204 (rank : 53)
Query Neighborhood Hits	158	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.122475 (rank : 54)
Query Neighborhood Hits	158	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.111557 (rank : 56)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.070873 (rank : 71)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG3_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.101055 (rank : 60)
Query Neighborhood Hits	158	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.099658 (rank : 61)
Query Neighborhood Hits	158	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG4_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.062654 (rank : 82)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ3_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.060717 (rank : 83)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	35
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.059645 (rank : 85)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ5_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.069916 (rank : 73)
Query Neighborhood Hits	158	Target Neighborhood Hits	163	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

MCLN2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.060453 (rank : 84)
Query Neighborhood Hits	158	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

PKDRE_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.072087 (rank : 70)
Query Neighborhood Hits	158	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

TRPV3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.051267 (rank : 89)
Query Neighborhood Hits	158	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

Hits sorted by NC score

CAC1C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	158
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
NC score	0.997417 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	97
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1S_HUMAN
NC score	0.993726 (rank : 3)	θ value	0 (rank : 12)
Query Neighborhood Hits	158	Target Neighborhood Hits	92	Shared Neighborhood Hits	60
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1D_HUMAN
NC score	0.993159 (rank : 4)	θ value	0 (rank : 7)
Query Neighborhood Hits	158	Target Neighborhood Hits	118	Shared Neighborhood Hits	59
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1S_MOUSE
NC score	0.993102 (rank : 5)	θ value	0 (rank : 13)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	60
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1F_MOUSE
NC score	0.991921 (rank : 6)	θ value	0 (rank : 11)
Query Neighborhood Hits	158	Target Neighborhood Hits	142	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.991536 (rank : 7)	θ value	0 (rank : 10)
Query Neighborhood Hits	158	Target Neighborhood Hits	141	Shared Neighborhood Hits	61
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1E_MOUSE
NC score	0.956957 (rank : 8)	θ value	0 (rank : 9)
Query Neighborhood Hits	158	Target Neighborhood Hits	167	Shared Neighborhood Hits	56
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_HUMAN
NC score	0.956906 (rank : 9)	θ value	0 (rank : 8)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	57
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1B_HUMAN
NC score	0.953187 (rank : 10)	θ value	0 (rank : 3)
Query Neighborhood Hits	158	Target Neighborhood Hits	257	Shared Neighborhood Hits	59
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_MOUSE
NC score	0.952074 (rank : 11)	θ value	0 (rank : 2)
Query Neighborhood Hits	158	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_MOUSE
NC score	0.947621 (rank : 12)	θ value	0 (rank : 4)
Query Neighborhood Hits	158	Target Neighborhood Hits	351	Shared Neighborhood Hits	58
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_HUMAN
NC score	0.943432 (rank : 13)	θ value	0 (rank : 1)
Query Neighborhood Hits	158	Target Neighborhood Hits	387	Shared Neighborhood Hits	62
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1I_HUMAN
NC score	0.888878 (rank : 14)	θ value	7.71989e-68 (rank : 16)
Query Neighborhood Hits	158	Target Neighborhood Hits	138	Shared Neighborhood Hits	59
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_MOUSE
NC score	0.862526 (rank : 15)	θ value	7.24236e-58 (rank : 30)
Query Neighborhood Hits	158	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

CAC1H_HUMAN
NC score	0.859437 (rank : 16)	θ value	1.90589e-58 (rank : 25)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	64
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SC11A_MOUSE
NC score	0.854321 (rank : 17)	θ value	1.2268e-81 (rank : 15)
Query Neighborhood Hits	158	Target Neighborhood Hits	116	Shared Neighborhood Hits	59
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SC11A_HUMAN
NC score	0.851551 (rank : 18)	θ value	1.90147e-66 (rank : 17)
Query Neighborhood Hits	158	Target Neighborhood Hits	111	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SCN7A_HUMAN
NC score	0.848490 (rank : 19)	θ value	1.88829e-90 (rank : 14)
Query Neighborhood Hits	158	Target Neighborhood Hits	135	Shared Neighborhood Hits	52
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN5A_HUMAN
NC score	0.845448 (rank : 20)	θ value	2.48917e-58 (rank : 27)
Query Neighborhood Hits	158	Target Neighborhood Hits	145	Shared Neighborhood Hits	59
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1G_HUMAN
NC score	0.844169 (rank : 21)	θ value	4.24587e-58 (rank : 29)
Query Neighborhood Hits	158	Target Neighborhood Hits	587	Shared Neighborhood Hits	59
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN4A_HUMAN
NC score	0.844145 (rank : 22)	θ value	1.77973e-64 (rank : 21)
Query Neighborhood Hits	158	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN3A_HUMAN
NC score	0.836907 (rank : 23)	θ value	6.11685e-65 (rank : 18)
Query Neighborhood Hits	158	Target Neighborhood Hits	115	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SC10A_MOUSE
NC score	0.834721 (rank : 24)	θ value	3.25095e-58 (rank : 28)
Query Neighborhood Hits	158	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SCN2A_HUMAN
NC score	0.834164 (rank : 25)	θ value	7.98882e-65 (rank : 19)
Query Neighborhood Hits	158	Target Neighborhood Hits	157	Shared Neighborhood Hits	59
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN9A_HUMAN
NC score	0.833834 (rank : 26)	θ value	1.04338e-64 (rank : 20)
Query Neighborhood Hits	158	Target Neighborhood Hits	157	Shared Neighborhood Hits	60
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN8A_HUMAN
NC score	0.832798 (rank : 27)	θ value	6.55044e-59 (rank : 23)
Query Neighborhood Hits	158	Target Neighborhood Hits	135	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN1A_HUMAN
NC score	0.831669 (rank : 28)	θ value	5.92465e-60 (rank : 22)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	60
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SC10A_HUMAN
NC score	0.830420 (rank : 29)	θ value	2.48917e-58 (rank : 26)
Query Neighborhood Hits	158	Target Neighborhood Hits	116	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

SCN8A_MOUSE
NC score	0.830152 (rank : 30)	θ value	1.45929e-58 (rank : 24)
Query Neighborhood Hits	158	Target Neighborhood Hits	136	Shared Neighborhood Hits	58
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

PK2L2_HUMAN
NC score	0.389723 (rank : 31)	θ value	2.36244e-08 (rank : 31)
Query Neighborhood Hits	158	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L1_HUMAN
NC score	0.355677 (rank : 32)	θ value	2.88788e-06 (rank : 34)
Query Neighborhood Hits	158	Target Neighborhood Hits	132	Shared Neighborhood Hits	38
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.353315 (rank : 33)	θ value	1.53129e-07 (rank : 33)
Query Neighborhood Hits	158	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PKD2_MOUSE
NC score	0.341152 (rank : 34)	θ value	2.44474e-05 (rank : 36)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	37
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

PKD2_HUMAN
NC score	0.336289 (rank : 35)	θ value	8.97725e-08 (rank : 32)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	35
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

KCNF1_HUMAN
NC score	0.237582 (rank : 36)	θ value	1.87187e-05 (rank : 35)
Query Neighborhood Hits	158	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNV2_HUMAN
NC score	0.223221 (rank : 37)	θ value	0.0330416 (rank : 49)
Query Neighborhood Hits	158	Target Neighborhood Hits	137	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNB2_HUMAN
NC score	0.206996 (rank : 38)	θ value	0.00102713 (rank : 37)
Query Neighborhood Hits	158	Target Neighborhood Hits	212	Shared Neighborhood Hits	59
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS2_MOUSE
NC score	0.198476 (rank : 39)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	58
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.195064 (rank : 40)	θ value	0.0113563 (rank : 42)
Query Neighborhood Hits	158	Target Neighborhood Hits	129	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB1_MOUSE
NC score	0.194443 (rank : 41)	θ value	0.00134147 (rank : 39)
Query Neighborhood Hits	158	Target Neighborhood Hits	154	Shared Neighborhood Hits	58
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.194333 (rank : 42)	θ value	0.00134147 (rank : 38)
Query Neighborhood Hits	158	Target Neighborhood Hits	169	Shared Neighborhood Hits	57
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCND3_MOUSE
NC score	0.176363 (rank : 43)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	158	Target Neighborhood Hits	162	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.176208 (rank : 44)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	158	Target Neighborhood Hits	162	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS3_HUMAN
NC score	0.173293 (rank : 45)	θ value	0.00134147 (rank : 40)
Query Neighborhood Hits	158	Target Neighborhood Hits	125	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCND2_MOUSE
NC score	0.169915 (rank : 46)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	158	Target Neighborhood Hits	156	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.169766 (rank : 47)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	158	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND1_MOUSE
NC score	0.160734 (rank : 48)	θ value	0.00509761 (rank : 41)
Query Neighborhood Hits	158	Target Neighborhood Hits	165	Shared Neighborhood Hits	56
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
NC score	0.156378 (rank : 49)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	158	Target Neighborhood Hits	160	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNS1_HUMAN
NC score	0.146699 (rank : 50)	θ value	0.0431538 (rank : 54)
Query Neighborhood Hits	158	Target Neighborhood Hits	116	Shared Neighborhood Hits	55
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS1_MOUSE
NC score	0.136162 (rank : 51)	θ value	0.0193708 (rank : 43)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	49
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

TPTE2_HUMAN
NC score	0.130599 (rank : 52)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	158	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q6XPS3, Q5VUH2, Q8WWL4, Q8WWL5	Gene names	TPTE2, TPIP
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (TPTE and PTEN homologous inositol lipid phosphatase) (Lipid phosphatase TPIP).

KCNC1_HUMAN
NC score	0.124204 (rank : 53)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	158	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
NC score	0.122475 (rank : 54)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	158	Target Neighborhood Hits	133	Shared Neighborhood Hits	52
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.120058 (rank : 55)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	158	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
NC score	0.111557 (rank : 56)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	50
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC3_HUMAN
NC score	0.107844 (rank : 57)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	158	Target Neighborhood Hits	256	Shared Neighborhood Hits	53
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.106282 (rank : 58)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	158	Target Neighborhood Hits	173	Shared Neighborhood Hits	51
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

PKDRE_HUMAN
NC score	0.101153 (rank : 59)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	158	Target Neighborhood Hits	64	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NTG1, O95850	Gene names	PKDREJ
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG3_HUMAN
NC score	0.101055 (rank : 60)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	158	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.099658 (rank : 61)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	158	Target Neighborhood Hits	91	Shared Neighborhood Hits	43
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNQ4_HUMAN
NC score	0.096294 (rank : 62)	θ value	0.0252991 (rank : 46)
Query Neighborhood Hits	158	Target Neighborhood Hits	136	Shared Neighborhood Hits	38
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

TPTE_HUMAN
NC score	0.091427 (rank : 63)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	158	Target Neighborhood Hits	53	Shared Neighborhood Hits	24
SwissProt Accessions	P56180, Q6XPS4, Q6XPS5, Q71JA8, Q8NCS8	Gene names	TPTE
Domain Architecture
Description	Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Transmembrane phosphatase with tensin homology) (Protein BJ-HCC-5).

KCNQ1_MOUSE
NC score	0.081093 (rank : 64)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	158	Target Neighborhood Hits	175	Shared Neighborhood Hits	37
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA1_MOUSE
NC score	0.080231 (rank : 65)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.078183 (rank : 66)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	158	Target Neighborhood Hits	104	Shared Neighborhood Hits	39
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA2_MOUSE
NC score	0.077419 (rank : 67)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	158	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA6_MOUSE
NC score	0.076416 (rank : 68)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	158	Target Neighborhood Hits	106	Shared Neighborhood Hits	39
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA2_HUMAN
NC score	0.076410 (rank : 69)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	158	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

PKDRE_MOUSE
NC score	0.072087 (rank : 70)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	158	Target Neighborhood Hits	76	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

KCNG1_HUMAN
NC score	0.070873 (rank : 71)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG2_HUMAN
NC score	0.070328 (rank : 72)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	158	Target Neighborhood Hits	83	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNQ5_HUMAN
NC score	0.069916 (rank : 73)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	158	Target Neighborhood Hits	163	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNA6_HUMAN
NC score	0.069600 (rank : 74)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	158	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNQ2_HUMAN
NC score	0.068769 (rank : 75)	θ value	0.0431538 (rank : 53)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	31
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ1_HUMAN
NC score	0.068252 (rank : 76)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	34
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNA5_MOUSE
NC score	0.067406 (rank : 77)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	158	Target Neighborhood Hits	119	Shared Neighborhood Hits	37
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA3_HUMAN
NC score	0.065308 (rank : 78)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	158	Target Neighborhood Hits	101	Shared Neighborhood Hits	35
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNQ2_MOUSE
NC score	0.064952 (rank : 79)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	158	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNA3_MOUSE
NC score	0.064439 (rank : 80)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	158	Target Neighborhood Hits	103	Shared Neighborhood Hits	33
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.062798 (rank : 81)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	158	Target Neighborhood Hits	124	Shared Neighborhood Hits	35
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNG4_HUMAN
NC score	0.062654 (rank : 82)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNQ3_HUMAN
NC score	0.060717 (rank : 83)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	158	Target Neighborhood Hits	114	Shared Neighborhood Hits	35
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

MCLN2_MOUSE
NC score	0.060453 (rank : 84)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	158	Target Neighborhood Hits	31	Shared Neighborhood Hits	17
SwissProt Accessions	Q8K595, Q3UCG4, Q8K2T6, Q9CQD3	Gene names	Mcoln2
Domain Architecture	No domain graphic available
Description	Mucolipin-2.

KCNQ3_MOUSE
NC score	0.059645 (rank : 85)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	158	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

DJBP_MOUSE
NC score	0.057734 (rank : 86)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	158	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

KCNA4_MOUSE
NC score	0.055437 (rank : 87)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	158	Target Neighborhood Hits	98	Shared Neighborhood Hits	28
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA4_HUMAN
NC score	0.055160 (rank : 88)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	158	Target Neighborhood Hits	108	Shared Neighborhood Hits	29
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

TRPV3_HUMAN
NC score	0.051267 (rank : 89)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	158	Target Neighborhood Hits	198	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

IWS1_MOUSE
NC score	0.035299 (rank : 90)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	158	Target Neighborhood Hits	1258	Shared Neighborhood Hits	41
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RILP_HUMAN
NC score	0.034011 (rank : 91)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	158	Target Neighborhood Hits	249	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NA2, Q71RE6, Q9BSL3, Q9BYS3	Gene names	RILP
Domain Architecture	No domain graphic available
Description	Rab-interacting lysosomal protein.

NIPBL_HUMAN
NC score	0.033805 (rank : 92)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	158	Target Neighborhood Hits	1311	Shared Neighborhood Hits	32
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

DNL3_HUMAN
NC score	0.028612 (rank : 93)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	158	Target Neighborhood Hits	49	Shared Neighborhood Hits	9
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

TUR8_MOUSE
NC score	0.028404 (rank : 94)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	158	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P19473	Gene names	Trap1a, P1a
Domain Architecture	No domain graphic available
Description	Tumor rejection antigen P815A.

SF3B1_MOUSE
NC score	0.026715 (rank : 95)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	158	Target Neighborhood Hits	352	Shared Neighborhood Hits	10
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_HUMAN
NC score	0.026677 (rank : 96)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	158	Target Neighborhood Hits	341	Shared Neighborhood Hits	10
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

DNL3_MOUSE
NC score	0.025473 (rank : 97)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	158	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

BSCL2_HUMAN
NC score	0.024496 (rank : 98)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	158	Target Neighborhood Hits	148	Shared Neighborhood Hits	10
SwissProt Accessions	Q96G97, Q96SV1, Q9BSQ0	Gene names	BSCL2
Domain Architecture	No domain graphic available
Description	Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein).

TP53B_MOUSE
NC score	0.024042 (rank : 99)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	158	Target Neighborhood Hits	644	Shared Neighborhood Hits	25
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SEN34_MOUSE
NC score	0.021782 (rank : 100)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	158	Target Neighborhood Hits	158	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

LDOC1_MOUSE
NC score	0.021643 (rank : 101)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	158	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPY9	Gene names	Ldoc1
Domain Architecture	No domain graphic available
Description	Protein LDOC1.

IWS1_HUMAN
NC score	0.019427 (rank : 102)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	158	Target Neighborhood Hits	1241	Shared Neighborhood Hits	34
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

NASP_HUMAN
NC score	0.018979 (rank : 103)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	158	Target Neighborhood Hits	709	Shared Neighborhood Hits	28
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

MB3L2_HUMAN
NC score	0.017372 (rank : 104)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	158	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NHZ7	Gene names	MBD3L2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 3-like 2 (MBD3-like 2).

RBBP6_HUMAN
NC score	0.016680 (rank : 105)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	158	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FSCN1_MOUSE
NC score	0.015542 (rank : 106)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	158	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q61553, O09099, O09156	Gene names	Fscn1, Fan1, Snl
Domain Architecture
Description	Fascin (Singed-like protein).

FSCN1_HUMAN
NC score	0.015424 (rank : 107)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	158	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q16658, Q96IC5, Q9BRF1	Gene names	FSCN1, FAN1, HSN, SNL
Domain Architecture
Description	Fascin (Singed-like protein) (55 kDa actin-bundling protein) (p55).

RGS3_MOUSE
NC score	0.015385 (rank : 108)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	158	Target Neighborhood Hits	1621	Shared Neighborhood Hits	39
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

AKA12_HUMAN
NC score	0.015329 (rank : 109)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	158	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DJBP_HUMAN
NC score	0.015071 (rank : 110)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	158	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

ACINU_HUMAN
NC score	0.014551 (rank : 111)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	158	Target Neighborhood Hits	828	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SELPL_MOUSE
NC score	0.014411 (rank : 112)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	158	Target Neighborhood Hits	588	Shared Neighborhood Hits	11
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

ADDB_HUMAN
NC score	0.013852 (rank : 113)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	158	Target Neighborhood Hits	142	Shared Neighborhood Hits	10
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

SEN34_HUMAN
NC score	0.013556 (rank : 114)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	158	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BSV6, Q9BVT1, Q9H6H5	Gene names	TSEN34, LENG5, SEN34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (HsSen34) (Leukocyte receptor cluster member 5).

APLP2_HUMAN
NC score	0.013382 (rank : 115)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	158	Target Neighborhood Hits	193	Shared Neighborhood Hits	7
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

LEO1_MOUSE
NC score	0.013028 (rank : 116)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	158	Target Neighborhood Hits	946	Shared Neighborhood Hits	32
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PCX3_MOUSE
NC score	0.012770 (rank : 117)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	158	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VI59	Gene names	Pcnxl3
Domain Architecture
Description	Pecanex-like protein 3.

BUB1B_MOUSE
NC score	0.012728 (rank : 118)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	158	Target Neighborhood Hits	202	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

ADDB_MOUSE
NC score	0.012371 (rank : 119)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	158	Target Neighborhood Hits	574	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

REL_MOUSE
NC score	0.010631 (rank : 120)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	158	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

DGLA_HUMAN
NC score	0.010314 (rank : 121)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	158	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4D2, Q6WQJ0	Gene names	NSDDR, C11orf11, KIAA0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

DGLA_MOUSE
NC score	0.009985 (rank : 122)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	158	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q6WQJ1, Q6ZQ76	Gene names	Nsddr, Kiaa0659
Domain Architecture	No domain graphic available
Description	Sn1-specific diacylglycerol lipase alpha (EC 3.1.1.-) (DGL-alpha) (Neural stem cell-derived dendrite regulator).

TXD13_MOUSE
NC score	0.009790 (rank : 123)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	158	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

APHC_HUMAN
NC score	0.009186 (rank : 124)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	158	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUN7	Gene names	PHCA, APHC
Domain Architecture
Description	Alkaline phytoceramidase (EC 3.5.1.-) (aPHC) (Alkaline ceramidase) (Alkaline dihydroceramidase SB89).

MAP1B_MOUSE
NC score	0.008738 (rank : 125)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	158	Target Neighborhood Hits	977	Shared Neighborhood Hits	33
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TXD13_HUMAN
NC score	0.008735 (rank : 126)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	158	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

BTC_HUMAN
NC score	0.008500 (rank : 127)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	158	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

CD20_HUMAN
NC score	0.008252 (rank : 128)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	158	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	P11836, P08984, Q13963	Gene names	MS4A1, CD20
Domain Architecture
Description	B-lymphocyte antigen CD20 (B-lymphocyte surface antigen B1) (Leu-16) (Bp35).

FRG1_MOUSE
NC score	0.007754 (rank : 129)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	158	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FRG1_HUMAN
NC score	0.007574 (rank : 130)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	158	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

FANCJ_HUMAN
NC score	0.007314 (rank : 131)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	158	Target Neighborhood Hits	72	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BX63, Q8NCI5	Gene names	BRIP1, BACH1, FANCJ
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

KCNH4_HUMAN
NC score	0.007181 (rank : 132)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	158	Target Neighborhood Hits	177	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

AXN1_HUMAN
NC score	0.007143 (rank : 133)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	158	Target Neighborhood Hits	99	Shared Neighborhood Hits	4
SwissProt Accessions	O15169, Q4TT26, Q4TT27, Q86YA7, Q8WVW6, Q96S28	Gene names	AXIN1, AXIN
Domain Architecture
Description	Axin-1 (Axis inhibition protein 1) (hAxin).

AP3B2_HUMAN
NC score	0.006820 (rank : 134)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	158	Target Neighborhood Hits	246	Shared Neighborhood Hits	17
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

APLP1_MOUSE
NC score	0.006666 (rank : 135)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	158	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

MUC1_MOUSE
NC score	0.006498 (rank : 136)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	158	Target Neighborhood Hits	388	Shared Neighborhood Hits	15
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

SH2D3_HUMAN
NC score	0.006397 (rank : 137)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	158	Target Neighborhood Hits	188	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N5H7, Q5HYE5, Q6UY42, Q8N6X3, Q9Y2X5	Gene names	SH2D3C, NSP3
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 3C (Novel SH2-containing protein 3).

APBA1_HUMAN
NC score	0.006119 (rank : 138)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	158	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CDA7L_HUMAN
NC score	0.006077 (rank : 139)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	158	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GN5, Q6PIL4, Q86YT0, Q8IXN5, Q96C70, Q9H9A2, Q9NPV2	Gene names	CDCA7L, HR1, JPO2, R1
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2).

CALX_MOUSE
NC score	0.005978 (rank : 140)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	158	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	P35564	Gene names	Canx
Domain Architecture
Description	Calnexin precursor.

POT15_HUMAN
NC score	0.005558 (rank : 141)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	158	Target Neighborhood Hits	893	Shared Neighborhood Hits	22
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

CALX_HUMAN
NC score	0.005486 (rank : 142)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	158	Target Neighborhood Hits	96	Shared Neighborhood Hits	9
SwissProt Accessions	P27824	Gene names	CANX
Domain Architecture
Description	Calnexin precursor (Major histocompatibility complex class I antigen- binding protein p88) (p90) (IP90).

ANR21_HUMAN
NC score	0.005354 (rank : 143)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	158	Target Neighborhood Hits	864	Shared Neighborhood Hits	23
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

GATA4_MOUSE
NC score	0.005308 (rank : 144)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	158	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q08369, P97491, Q9QZK4	Gene names	Gata4, Gata-4
Domain Architecture
Description	Transcription factor GATA-4 (GATA-binding factor 4).

KLC2_MOUSE
NC score	0.004945 (rank : 145)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	158	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

ANX11_MOUSE
NC score	0.004932 (rank : 146)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	158	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	P97384	Gene names	Anxa11, Anx11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50).

CSTN1_MOUSE
NC score	0.004913 (rank : 147)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	158	Target Neighborhood Hits	175	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EPL2	Gene names	Clstn1, Cs1, Cstn1
Domain Architecture
Description	Calsyntenin-1 precursor.

KLC2_HUMAN
NC score	0.004896 (rank : 148)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	158	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

CXA12_MOUSE
NC score	0.004858 (rank : 149)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	158	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQU6, Q6TLV2, Q8BQS2, Q9EPM1	Gene names	Gja12
Domain Architecture	No domain graphic available
Description	Gap junction alpha-12 protein (Connexin-47) (Cx47).

TCRG1_HUMAN
NC score	0.004301 (rank : 150)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	158	Target Neighborhood Hits	929	Shared Neighborhood Hits	26
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

MLL3_HUMAN
NC score	0.004243 (rank : 151)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	158	Target Neighborhood Hits	1644	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RGS3_HUMAN
NC score	0.004047 (rank : 152)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	158	Target Neighborhood Hits	1375	Shared Neighborhood Hits	21
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MYPN_MOUSE
NC score	0.003952 (rank : 153)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	158	Target Neighborhood Hits	421	Shared Neighborhood Hits	7
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

KLC4_HUMAN
NC score	0.003792 (rank : 154)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	158	Target Neighborhood Hits	327	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

SMC3_HUMAN
NC score	0.003715 (rank : 155)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	158	Target Neighborhood Hits	1186	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

ZC3H8_MOUSE
NC score	0.003683 (rank : 156)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	158	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JJ48, Q80X92	Gene names	Zc3h8, Fliz1, Zc3hdc8
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 8 (Fetal liver zinc finger protein 1).

SMC3_MOUSE
NC score	0.003675 (rank : 157)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	158	Target Neighborhood Hits	1187	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ANX11_HUMAN
NC score	0.003668 (rank : 158)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	158	Target Neighborhood Hits	192	Shared Neighborhood Hits	6
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

AT132_MOUSE
NC score	0.003475 (rank : 159)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	158	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CTG6, Q8CG98	Gene names	Atp13a2
Domain Architecture	No domain graphic available
Description	Probable cation-transporting ATPase 13A2 (EC 3.6.3.-).

B4GN3_MOUSE
NC score	0.003306 (rank : 160)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	158	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

CDR2_HUMAN
NC score	0.003250 (rank : 161)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	158	Target Neighborhood Hits	404	Shared Neighborhood Hits	10
SwissProt Accessions	Q01850, Q13977	Gene names	CDR2, PCD17
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related protein 2 (Paraneoplastic cerebellar degeneration-associated antigen) (Major Yo paraneoplastic antigen).

RNPC1_MOUSE
NC score	0.003128 (rank : 162)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	158	Target Neighborhood Hits	190	Shared Neighborhood Hits	2
SwissProt Accessions	Q62176, Q922Z2	Gene names	Rnpc1, Seb4, Seb4l
Domain Architecture
Description	RNA-binding region-containing protein 1 (ssDNA-binding protein SEB4).

MYB_MOUSE
NC score	0.002967 (rank : 163)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	158	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P06876, Q61929	Gene names	Myb
Domain Architecture
Description	Myb proto-oncogene protein (C-myb).

CALD1_HUMAN
NC score	0.002484 (rank : 164)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	158	Target Neighborhood Hits	959	Shared Neighborhood Hits	25
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

MTMR5_HUMAN
NC score	0.002473 (rank : 165)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	158	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

COFA1_MOUSE
NC score	0.002041 (rank : 166)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	158	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	O35206, Q9EQD9	Gene names	Col15a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV)].

EHMT2_HUMAN
NC score	0.001930 (rank : 167)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	158	Target Neighborhood Hits	498	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ES8L3_HUMAN
NC score	0.001893 (rank : 168)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	158	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE67, Q5T8Q6, Q5T8Q7, Q5T8Q8, Q96E47, Q9H719	Gene names	EPS8L3, EPS8R3
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 3 (Epidermal growth factor receptor pathway substrate 8-related protein 3) (EPS8-like protein 3).

JHD1B_MOUSE
NC score	0.001861 (rank : 169)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	158	Target Neighborhood Hits	214	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

CRKL_MOUSE
NC score	0.001619 (rank : 170)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	158	Target Neighborhood Hits	307	Shared Neighborhood Hits	5
SwissProt Accessions	P47941, Q3TQ18, Q8BGC5	Gene names	Crkl, Crkol
Domain Architecture
Description	Crk-like protein.

SKIL_HUMAN
NC score	0.001442 (rank : 171)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	158	Target Neighborhood Hits	460	Shared Neighborhood Hits	13
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

T2R16_HUMAN
NC score	0.001294 (rank : 172)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	158	Target Neighborhood Hits	64	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYV7, Q502V3, Q549U8, Q645W1	Gene names	TAS2R16
Domain Architecture
Description	Taste receptor type 2 member 16 (T2R16).

TPR_HUMAN
NC score	0.001082 (rank : 173)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	158	Target Neighborhood Hits	1921	Shared Neighborhood Hits	37
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

PROP_MOUSE
NC score	0.001055 (rank : 174)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	158	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

BAZ2B_HUMAN
NC score	0.001003 (rank : 175)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	158	Target Neighborhood Hits	803	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

TENA_MOUSE
NC score	0.000427 (rank : 176)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	158	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

KI21A_MOUSE
NC score	-0.000315 (rank : 177)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	158	Target Neighborhood Hits	1317	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

AKAP9_HUMAN
NC score	-0.001550 (rank : 178)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	158	Target Neighborhood Hits	1710	Shared Neighborhood Hits	23
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

OR4B1_HUMAN
NC score	-0.004195 (rank : 179)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	158	Target Neighborhood Hits	652	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NGF8, Q6IF75, Q96R64	Gene names	OR4B1
Domain Architecture
Description	Olfactory receptor 4B1 (OST208) (Olfactory receptor OR11-106).

OR6Y1_HUMAN
NC score	-0.004224 (rank : 180)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	158	Target Neighborhood Hits	701	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NGX8, Q6IFS0	Gene names	OR6Y1, OR6Y2
Domain Architecture
Description	Olfactory receptor 6Y1 (Olfactory receptor OR1-11).

MAST2_MOUSE
NC score	-0.004313 (rank : 181)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	158	Target Neighborhood Hits	1110	Shared Neighborhood Hits	11
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

ZFP13_MOUSE
NC score	-0.004531 (rank : 182)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	158	Target Neighborhood Hits	771	Shared Neighborhood Hits	6
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).