Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : KCNQ1_HUMAN

For an explanation of this page, click here

KCNQ1_HUMAN
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNQ1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	99
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	0 (rank : 2)	NC score	0.993085 (rank : 2)
Query Neighborhood Hits	99	Target Neighborhood Hits	175	Shared Neighborhood Hits	82
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ5_HUMAN
θ value	2.2151e-115 (rank : 3)	NC score	0.964206 (rank : 3)
Query Neighborhood Hits	99	Target Neighborhood Hits	163	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ3_MOUSE
θ value	2.01279e-100 (rank : 4)	NC score	0.956824 (rank : 7)
Query Neighborhood Hits	99	Target Neighborhood Hits	105	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
θ value	3.4333e-100 (rank : 5)	NC score	0.955889 (rank : 8)
Query Neighborhood Hits	99	Target Neighborhood Hits	114	Shared Neighborhood Hits	72
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ2_MOUSE
θ value	3.55291e-97 (rank : 6)	NC score	0.961767 (rank : 6)
Query Neighborhood Hits	99	Target Neighborhood Hits	163	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ4_HUMAN
θ value	1.76329e-96 (rank : 7)	NC score	0.963623 (rank : 4)
Query Neighborhood Hits	99	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ2_HUMAN
θ value	9.6755e-95 (rank : 8)	NC score	0.963049 (rank : 5)
Query Neighborhood Hits	99	Target Neighborhood Hits	114	Shared Neighborhood Hits	73
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNA3_HUMAN
θ value	1.74391e-19 (rank : 9)	NC score	0.774342 (rank : 9)
Query Neighborhood Hits	99	Target Neighborhood Hits	101	Shared Neighborhood Hits	70
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	3.88503e-19 (rank : 10)	NC score	0.772977 (rank : 11)
Query Neighborhood Hits	99	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCND2_MOUSE
θ value	3.88503e-19 (rank : 11)	NC score	0.754173 (rank : 26)
Query Neighborhood Hits	99	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
θ value	5.07402e-19 (rank : 12)	NC score	0.754172 (rank : 27)
Query Neighborhood Hits	99	Target Neighborhood Hits	154	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNA2_HUMAN
θ value	6.62687e-19 (rank : 13)	NC score	0.769935 (rank : 18)
Query Neighborhood Hits	99	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	6.62687e-19 (rank : 14)	NC score	0.770094 (rank : 17)
Query Neighborhood Hits	99	Target Neighborhood Hits	102	Shared Neighborhood Hits	72
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA6_MOUSE
θ value	6.62687e-19 (rank : 15)	NC score	0.772214 (rank : 14)
Query Neighborhood Hits	99	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA4_MOUSE
θ value	8.65492e-19 (rank : 16)	NC score	0.773094 (rank : 10)
Query Neighborhood Hits	99	Target Neighborhood Hits	98	Shared Neighborhood Hits	69
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCND1_MOUSE
θ value	1.13037e-18 (rank : 17)	NC score	0.751261 (rank : 33)
Query Neighborhood Hits	99	Target Neighborhood Hits	165	Shared Neighborhood Hits	79
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCND1_HUMAN
θ value	1.47631e-18 (rank : 18)	NC score	0.752393 (rank : 30)
Query Neighborhood Hits	99	Target Neighborhood Hits	160	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNA1_HUMAN
θ value	1.92812e-18 (rank : 19)	NC score	0.772890 (rank : 12)
Query Neighborhood Hits	99	Target Neighborhood Hits	104	Shared Neighborhood Hits	71
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	1.92812e-18 (rank : 20)	NC score	0.772716 (rank : 13)
Query Neighborhood Hits	99	Target Neighborhood Hits	103	Shared Neighborhood Hits	71
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA5_MOUSE
θ value	3.28887e-18 (rank : 21)	NC score	0.769366 (rank : 19)
Query Neighborhood Hits	99	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCND3_HUMAN
θ value	4.29542e-18 (rank : 22)	NC score	0.753355 (rank : 29)
Query Neighborhood Hits	99	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	4.29542e-18 (rank : 23)	NC score	0.753779 (rank : 28)
Query Neighborhood Hits	99	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNA4_HUMAN
θ value	5.60996e-18 (rank : 24)	NC score	0.771306 (rank : 15)
Query Neighborhood Hits	99	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA6_HUMAN
θ value	5.60996e-18 (rank : 25)	NC score	0.770886 (rank : 16)
Query Neighborhood Hits	99	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_HUMAN
θ value	9.56915e-18 (rank : 26)	NC score	0.768079 (rank : 20)
Query Neighborhood Hits	99	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNB2_HUMAN
θ value	2.13179e-17 (rank : 27)	NC score	0.751155 (rank : 34)
Query Neighborhood Hits	99	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNB1_HUMAN
θ value	2.35696e-16 (rank : 28)	NC score	0.749933 (rank : 36)
Query Neighborhood Hits	99	Target Neighborhood Hits	169	Shared Neighborhood Hits	78
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	2.35696e-16 (rank : 29)	NC score	0.750006 (rank : 35)
Query Neighborhood Hits	99	Target Neighborhood Hits	154	Shared Neighborhood Hits	77
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNC3_HUMAN
θ value	2.35696e-16 (rank : 30)	NC score	0.752357 (rank : 31)
Query Neighborhood Hits	99	Target Neighborhood Hits	256	Shared Neighborhood Hits	74
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC1_MOUSE
θ value	3.07829e-16 (rank : 31)	NC score	0.758269 (rank : 23)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
θ value	4.02038e-16 (rank : 32)	NC score	0.757980 (rank : 24)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC3_MOUSE
θ value	4.02038e-16 (rank : 33)	NC score	0.752179 (rank : 32)
Query Neighborhood Hits	99	Target Neighborhood Hits	173	Shared Neighborhood Hits	73
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_HUMAN
θ value	8.95645e-16 (rank : 34)	NC score	0.762273 (rank : 22)
Query Neighborhood Hits	99	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNS3_HUMAN
θ value	1.52774e-15 (rank : 35)	NC score	0.749248 (rank : 38)
Query Neighborhood Hits	99	Target Neighborhood Hits	125	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNC4_MOUSE
θ value	2.60593e-15 (rank : 36)	NC score	0.763211 (rank : 21)
Query Neighborhood Hits	99	Target Neighborhood Hits	130	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG4_HUMAN
θ value	8.38298e-14 (rank : 37)	NC score	0.744189 (rank : 39)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNV2_HUMAN
θ value	1.09485e-13 (rank : 38)	NC score	0.732120 (rank : 43)
Query Neighborhood Hits	99	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNF1_HUMAN
θ value	7.09661e-13 (rank : 39)	NC score	0.749887 (rank : 37)
Query Neighborhood Hits	99	Target Neighborhood Hits	109	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNG2_HUMAN
θ value	2.0648e-12 (rank : 40)	NC score	0.755244 (rank : 25)
Query Neighborhood Hits	99	Target Neighborhood Hits	83	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG1_HUMAN
θ value	3.52202e-12 (rank : 41)	NC score	0.742602 (rank : 40)
Query Neighborhood Hits	99	Target Neighborhood Hits	103	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNS1_HUMAN
θ value	1.133e-10 (rank : 42)	NC score	0.731974 (rank : 44)
Query Neighborhood Hits	99	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG3_MOUSE
θ value	2.52405e-10 (rank : 43)	NC score	0.736971 (rank : 42)
Query Neighborhood Hits	99	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
θ value	3.29651e-10 (rank : 44)	NC score	0.738169 (rank : 41)
Query Neighborhood Hits	99	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNS2_HUMAN
θ value	3.29651e-10 (rank : 45)	NC score	0.731277 (rank : 46)
Query Neighborhood Hits	99	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	3.29651e-10 (rank : 46)	NC score	0.731684 (rank : 45)
Query Neighborhood Hits	99	Target Neighborhood Hits	130	Shared Neighborhood Hits	75
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS1_MOUSE
θ value	1.25267e-09 (rank : 47)	NC score	0.728445 (rank : 47)
Query Neighborhood Hits	99	Target Neighborhood Hits	114	Shared Neighborhood Hits	76
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNN4_MOUSE
θ value	6.87365e-08 (rank : 48)	NC score	0.443723 (rank : 48)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNN4_HUMAN
θ value	1.17247e-07 (rank : 49)	NC score	0.437071 (rank : 49)
Query Neighborhood Hits	99	Target Neighborhood Hits	90	Shared Neighborhood Hits	70
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNN1_HUMAN
θ value	0.00035302 (rank : 50)	NC score	0.346154 (rank : 52)
Query Neighborhood Hits	99	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_MOUSE
θ value	0.00298849 (rank : 51)	NC score	0.342836 (rank : 53)
Query Neighborhood Hits	99	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN2_HUMAN
θ value	0.00509761 (rank : 52)	NC score	0.342824 (rank : 54)
Query Neighborhood Hits	99	Target Neighborhood Hits	117	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	0.00509761 (rank : 53)	NC score	0.342798 (rank : 55)
Query Neighborhood Hits	99	Target Neighborhood Hits	120	Shared Neighborhood Hits	68
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_HUMAN
θ value	0.00665767 (rank : 54)	NC score	0.339069 (rank : 56)
Query Neighborhood Hits	99	Target Neighborhood Hits	216	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCMA1_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.425665 (rank : 51)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	68
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	0.0193708 (rank : 56)	NC score	0.426488 (rank : 50)
Query Neighborhood Hits	99	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNN3_MOUSE
θ value	0.0193708 (rank : 57)	NC score	0.331766 (rank : 57)
Query Neighborhood Hits	99	Target Neighborhood Hits	171	Shared Neighborhood Hits	69
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

SCN8A_HUMAN
θ value	0.0431538 (rank : 58)	NC score	0.073582 (rank : 105)
Query Neighborhood Hits	99	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	0.0431538 (rank : 59)	NC score	0.073361 (rank : 106)
Query Neighborhood Hits	99	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

KCNKA_HUMAN
θ value	0.0961366 (rank : 60)	NC score	0.208798 (rank : 58)
Query Neighborhood Hits	99	Target Neighborhood Hits	111	Shared Neighborhood Hits	70
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

CAC1H_MOUSE
θ value	0.21417 (rank : 61)	NC score	0.093499 (rank : 92)
Query Neighborhood Hits	99	Target Neighborhood Hits	230	Shared Neighborhood Hits	43
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

KCNK4_MOUSE
θ value	0.279714 (rank : 62)	NC score	0.119950 (rank : 87)
Query Neighborhood Hits	99	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

JIP4_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.020155 (rank : 134)
Query Neighborhood Hits	99	Target Neighborhood Hits	585	Shared Neighborhood Hits	7
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

KCNK6_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.170147 (rank : 63)
Query Neighborhood Hits	99	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNKF_HUMAN
θ value	0.47712 (rank : 65)	NC score	0.179357 (rank : 60)
Query Neighborhood Hits	99	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

CAC1S_MOUSE
θ value	0.813845 (rank : 66)	NC score	0.065992 (rank : 116)
Query Neighborhood Hits	99	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

PCLO_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.004263 (rank : 143)
Query Neighborhood Hits	99	Target Neighborhood Hits	2046	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

JIP4_MOUSE
θ value	1.06291 (rank : 68)	NC score	0.017159 (rank : 135)
Query Neighborhood Hits	99	Target Neighborhood Hits	593	Shared Neighborhood Hits	6
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

KCNK9_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.125164 (rank : 84)
Query Neighborhood Hits	99	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	1.06291 (rank : 70)	NC score	0.124365 (rank : 85)
Query Neighborhood Hits	99	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

ZN687_HUMAN
θ value	1.38821 (rank : 71)	NC score	-0.001151 (rank : 152)
Query Neighborhood Hits	99	Target Neighborhood Hits	1244	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

SC10A_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.062905 (rank : 120)
Query Neighborhood Hits	99	Target Neighborhood Hits	116	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CAC1H_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.086902 (rank : 99)
Query Neighborhood Hits	99	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

KCNK2_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.146804 (rank : 75)
Query Neighborhood Hits	99	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK3_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.160269 (rank : 68)
Query Neighborhood Hits	99	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.160222 (rank : 69)
Query Neighborhood Hits	99	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK5_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.154596 (rank : 71)
Query Neighborhood Hits	99	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNKG_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.170937 (rank : 62)
Query Neighborhood Hits	99	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

NRX2A_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.004674 (rank : 142)
Query Neighborhood Hits	99	Target Neighborhood Hits	614	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.008380 (rank : 139)
Query Neighborhood Hits	99	Target Neighborhood Hits	481	Shared Neighborhood Hits	8
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CAC1C_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.068252 (rank : 113)
Query Neighborhood Hits	99	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

HXA4_MOUSE
θ value	5.27518 (rank : 82)	NC score	-0.000627 (rank : 149)
Query Neighborhood Hits	99	Target Neighborhood Hits	379	Shared Neighborhood Hits	6
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

KCNK1_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.079856 (rank : 101)
Query Neighborhood Hits	99	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.078019 (rank : 102)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK2_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.142786 (rank : 77)
Query Neighborhood Hits	99	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

MAP1A_HUMAN
θ value	5.27518 (rank : 86)	NC score	-0.000122 (rank : 148)
Query Neighborhood Hits	99	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

P2RY2_MOUSE
θ value	5.27518 (rank : 87)	NC score	-0.000938 (rank : 151)
Query Neighborhood Hits	99	Target Neighborhood Hits	476	Shared Neighborhood Hits	3
SwissProt Accessions	P35383, O09031, Q9CPZ4	Gene names	P2ry2, P2ru1
Domain Architecture
Description	P2Y purinoceptor 2 (P2Y2) (P2U purinoceptor 1) (P2U1) (ATP receptor) (Purinergic receptor).

SNP25_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.011230 (rank : 137)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P60880, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	SNAP25, SNAP
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNP25_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.011230 (rank : 138)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P60879, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	Snap25, Snap
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

STX2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.003711 (rank : 144)
Query Neighborhood Hits	99	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

MYCL1_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.005497 (rank : 141)
Query Neighborhood Hits	99	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

RX_MOUSE
θ value	6.88961 (rank : 92)	NC score	-0.000931 (rank : 150)
Query Neighborhood Hits	99	Target Neighborhood Hits	429	Shared Neighborhood Hits	5
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SKIL_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.002312 (rank : 145)
Query Neighborhood Hits	99	Target Neighborhood Hits	460	Shared Neighborhood Hits	5
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

CSKI2_MOUSE
θ value	8.99809 (rank : 94)	NC score	-0.001886 (rank : 153)
Query Neighborhood Hits	99	Target Neighborhood Hits	812	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

KCNKH_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.184522 (rank : 59)
Query Neighborhood Hits	99	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

MAGI2_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.001926 (rank : 147)
Query Neighborhood Hits	99	Target Neighborhood Hits	373	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAGI2_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.002158 (rank : 146)
Query Neighborhood Hits	99	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

NDUAB_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.016106 (rank : 136)
Query Neighborhood Hits	99	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8B4	Gene names	Ndufa11
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase subunit B14.7) (Complex I-B14.7) (CI-B14.7).

TSC2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.005551 (rank : 140)
Query Neighborhood Hits	99	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

CAC1A_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.070663 (rank : 110)
Query Neighborhood Hits	99	Target Neighborhood Hits	387	Shared Neighborhood Hits	44
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.070809 (rank : 109)
Query Neighborhood Hits	99	Target Neighborhood Hits	267	Shared Neighborhood Hits	43
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.065096 (rank : 117)
Query Neighborhood Hits	99	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.072602 (rank : 107)
Query Neighborhood Hits	99	Target Neighborhood Hits	351	Shared Neighborhood Hits	39
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1C_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.068017 (rank : 114)
Query Neighborhood Hits	99	Target Neighborhood Hits	130	Shared Neighborhood Hits	30
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1D_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.063882 (rank : 118)
Query Neighborhood Hits	99	Target Neighborhood Hits	118	Shared Neighborhood Hits	35
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1E_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.059175 (rank : 124)
Query Neighborhood Hits	99	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.057649 (rank : 126)
Query Neighborhood Hits	99	Target Neighborhood Hits	167	Shared Neighborhood Hits	29
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1F_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.068665 (rank : 112)
Query Neighborhood Hits	99	Target Neighborhood Hits	141	Shared Neighborhood Hits	35
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.069524 (rank : 111)
Query Neighborhood Hits	99	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1G_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.070960 (rank : 108)
Query Neighborhood Hits	99	Target Neighborhood Hits	587	Shared Neighborhood Hits	37
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1I_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.089468 (rank : 95)
Query Neighborhood Hits	99	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1S_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.062018 (rank : 121)
Query Neighborhood Hits	99	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

KCD11_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.052319 (rank : 133)
Query Neighborhood Hits	99	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q693B1	Gene names	KCTD11, REN
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCD11_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.054021 (rank : 130)
Query Neighborhood Hits	99	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K485	Gene names	Kctd11, Ren
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCD14_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.090834 (rank : 94)
Query Neighborhood Hits	99	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BQ13	Gene names	KCTD14
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD14.

KCD15_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.159420 (rank : 70)
Query Neighborhood Hits	99	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q96SI1, Q9BVI6	Gene names	KCTD15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCD15_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.153772 (rank : 72)
Query Neighborhood Hits	99	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K0E1	Gene names	Kctd15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCD17_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.101902 (rank : 90)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

KCNK4_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.093349 (rank : 93)
Query Neighborhood Hits	99	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK7_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.075671 (rank : 104)
Query Neighborhood Hits	99	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.077415 (rank : 103)
Query Neighborhood Hits	99	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNKC_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.058365 (rank : 125)
Query Neighborhood Hits	99	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNRG_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.122294 (rank : 86)
Query Neighborhood Hits	99	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N5I3, Q8IU75, Q8N3Q9	Gene names	KCNRG, CLLD4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCNRG_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.116379 (rank : 88)
Query Neighborhood Hits	99	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q2TUM3, Q6P8J6, Q8C6V1	Gene names	Kcnrg, Clld4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCNT1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.175104 (rank : 61)
Query Neighborhood Hits	99	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNT1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.102593 (rank : 89)
Query Neighborhood Hits	99	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCTD1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.166186 (rank : 64)
Query Neighborhood Hits	99	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q719H9	Gene names	KCTD1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.166186 (rank : 65)
Query Neighborhood Hits	99	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q5M956, Q5EER9	Gene names	Kctd1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD2_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.143098 (rank : 76)
Query Neighborhood Hits	99	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCTD2_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.052781 (rank : 131)
Query Neighborhood Hits	99	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CEZ0	Gene names	Kctd2
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCTD3_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.138788 (rank : 79)
Query Neighborhood Hits	99	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

KCTD3_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.127961 (rank : 82)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BFX3, Q6P7X4	Gene names	Kctd3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3.

KCTD4_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.149766 (rank : 74)
Query Neighborhood Hits	99	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WVF5	Gene names	KCTD4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD4_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.150530 (rank : 73)
Query Neighborhood Hits	99	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D7X1, Q8CCQ3, Q9CYK4	Gene names	Kctd4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD5_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.132044 (rank : 81)
Query Neighborhood Hits	99	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD5_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.134096 (rank : 80)
Query Neighborhood Hits	99	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD6_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.161046 (rank : 67)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NC69, Q8NBS6, Q8TCA6	Gene names	KCTD6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD6_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.162672 (rank : 66)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BNL5, Q3TXX1	Gene names	Kctd6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD7_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.125980 (rank : 83)
Query Neighborhood Hits	99	Target Neighborhood Hits	74	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCTD7_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.142103 (rank : 78)
Query Neighborhood Hits	99	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCTD8_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.052689 (rank : 132)
Query Neighborhood Hits	99	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	Q50H33, Q8BR74, Q8C4C2, Q8C906, Q8C9B0, Q8CAA9	Gene names	Kctd8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCTD9_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.086045 (rank : 100)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L273, Q6NUM8, Q9NXV4	Gene names	KCTD9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCTD9_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.088401 (rank : 97)
Query Neighborhood Hits	99	Target Neighborhood Hits	63	Shared Neighborhood Hits	24
SwissProt Accessions	Q80UN1	Gene names	Kctd9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

SC10A_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.067859 (rank : 115)
Query Neighborhood Hits	99	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC11A_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.099287 (rank : 91)
Query Neighborhood Hits	99	Target Neighborhood Hits	111	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

SC11A_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.089163 (rank : 96)
Query Neighborhood Hits	99	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

SCN1A_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.056032 (rank : 127)
Query Neighborhood Hits	99	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN2A_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.054953 (rank : 129)
Query Neighborhood Hits	99	Target Neighborhood Hits	157	Shared Neighborhood Hits	28
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.059853 (rank : 122)
Query Neighborhood Hits	99	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN4A_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.087535 (rank : 98)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.059465 (rank : 123)
Query Neighborhood Hits	99	Target Neighborhood Hits	145	Shared Neighborhood Hits	31
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN7A_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.055557 (rank : 128)
Query Neighborhood Hits	99	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN9A_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.063414 (rank : 119)
Query Neighborhood Hits	99	Target Neighborhood Hits	157	Shared Neighborhood Hits	32
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

Hits sorted by NC score

KCNQ1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	99
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
NC score	0.993085 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	99	Target Neighborhood Hits	175	Shared Neighborhood Hits	82
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ5_HUMAN
NC score	0.964206 (rank : 3)	θ value	2.2151e-115 (rank : 3)
Query Neighborhood Hits	99	Target Neighborhood Hits	163	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ4_HUMAN
NC score	0.963623 (rank : 4)	θ value	1.76329e-96 (rank : 7)
Query Neighborhood Hits	99	Target Neighborhood Hits	136	Shared Neighborhood Hits	72
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ2_HUMAN
NC score	0.963049 (rank : 5)	θ value	9.6755e-95 (rank : 8)
Query Neighborhood Hits	99	Target Neighborhood Hits	114	Shared Neighborhood Hits	73
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.961767 (rank : 6)	θ value	3.55291e-97 (rank : 6)
Query Neighborhood Hits	99	Target Neighborhood Hits	163	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ3_MOUSE
NC score	0.956824 (rank : 7)	θ value	2.01279e-100 (rank : 4)
Query Neighborhood Hits	99	Target Neighborhood Hits	105	Shared Neighborhood Hits	72
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.955889 (rank : 8)	θ value	3.4333e-100 (rank : 5)
Query Neighborhood Hits	99	Target Neighborhood Hits	114	Shared Neighborhood Hits	72
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNA3_HUMAN
NC score	0.774342 (rank : 9)	θ value	1.74391e-19 (rank : 9)
Query Neighborhood Hits	99	Target Neighborhood Hits	101	Shared Neighborhood Hits	70
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA4_MOUSE
NC score	0.773094 (rank : 10)	θ value	8.65492e-19 (rank : 16)
Query Neighborhood Hits	99	Target Neighborhood Hits	98	Shared Neighborhood Hits	69
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA3_MOUSE
NC score	0.772977 (rank : 11)	θ value	3.88503e-19 (rank : 10)
Query Neighborhood Hits	99	Target Neighborhood Hits	103	Shared Neighborhood Hits	72
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA1_HUMAN
NC score	0.772890 (rank : 12)	θ value	1.92812e-18 (rank : 19)
Query Neighborhood Hits	99	Target Neighborhood Hits	104	Shared Neighborhood Hits	71
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
NC score	0.772716 (rank : 13)	θ value	1.92812e-18 (rank : 20)
Query Neighborhood Hits	99	Target Neighborhood Hits	103	Shared Neighborhood Hits	71
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA6_MOUSE
NC score	0.772214 (rank : 14)	θ value	6.62687e-19 (rank : 15)
Query Neighborhood Hits	99	Target Neighborhood Hits	106	Shared Neighborhood Hits	73
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA4_HUMAN
NC score	0.771306 (rank : 15)	θ value	5.60996e-18 (rank : 24)
Query Neighborhood Hits	99	Target Neighborhood Hits	108	Shared Neighborhood Hits	71
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA6_HUMAN
NC score	0.770886 (rank : 16)	θ value	5.60996e-18 (rank : 25)
Query Neighborhood Hits	99	Target Neighborhood Hits	100	Shared Neighborhood Hits	74
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA2_MOUSE
NC score	0.770094 (rank : 17)	θ value	6.62687e-19 (rank : 14)
Query Neighborhood Hits	99	Target Neighborhood Hits	102	Shared Neighborhood Hits	72
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.769935 (rank : 18)	θ value	6.62687e-19 (rank : 13)
Query Neighborhood Hits	99	Target Neighborhood Hits	101	Shared Neighborhood Hits	72
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA5_MOUSE
NC score	0.769366 (rank : 19)	θ value	3.28887e-18 (rank : 21)
Query Neighborhood Hits	99	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNA5_HUMAN
NC score	0.768079 (rank : 20)	θ value	9.56915e-18 (rank : 26)
Query Neighborhood Hits	99	Target Neighborhood Hits	124	Shared Neighborhood Hits	71
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNC4_MOUSE
NC score	0.763211 (rank : 21)	θ value	2.60593e-15 (rank : 36)
Query Neighborhood Hits	99	Target Neighborhood Hits	130	Shared Neighborhood Hits	73
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC4_HUMAN
NC score	0.762273 (rank : 22)	θ value	8.95645e-16 (rank : 34)
Query Neighborhood Hits	99	Target Neighborhood Hits	141	Shared Neighborhood Hits	74
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC1_MOUSE
NC score	0.758269 (rank : 23)	θ value	3.07829e-16 (rank : 31)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
NC score	0.757980 (rank : 24)	θ value	4.02038e-16 (rank : 32)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	74
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNG2_HUMAN
NC score	0.755244 (rank : 25)	θ value	2.0648e-12 (rank : 40)
Query Neighborhood Hits	99	Target Neighborhood Hits	83	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCND2_MOUSE
NC score	0.754173 (rank : 26)	θ value	3.88503e-19 (rank : 11)
Query Neighborhood Hits	99	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.754172 (rank : 27)	θ value	5.07402e-19 (rank : 12)
Query Neighborhood Hits	99	Target Neighborhood Hits	154	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_MOUSE
NC score	0.753779 (rank : 28)	θ value	4.29542e-18 (rank : 23)
Query Neighborhood Hits	99	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.753355 (rank : 29)	θ value	4.29542e-18 (rank : 22)
Query Neighborhood Hits	99	Target Neighborhood Hits	162	Shared Neighborhood Hits	77
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND1_HUMAN
NC score	0.752393 (rank : 30)	θ value	1.47631e-18 (rank : 18)
Query Neighborhood Hits	99	Target Neighborhood Hits	160	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNC3_HUMAN
NC score	0.752357 (rank : 31)	θ value	2.35696e-16 (rank : 30)
Query Neighborhood Hits	99	Target Neighborhood Hits	256	Shared Neighborhood Hits	74
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
NC score	0.752179 (rank : 32)	θ value	4.02038e-16 (rank : 33)
Query Neighborhood Hits	99	Target Neighborhood Hits	173	Shared Neighborhood Hits	73
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCND1_MOUSE
NC score	0.751261 (rank : 33)	θ value	1.13037e-18 (rank : 17)
Query Neighborhood Hits	99	Target Neighborhood Hits	165	Shared Neighborhood Hits	79
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNB2_HUMAN
NC score	0.751155 (rank : 34)	θ value	2.13179e-17 (rank : 27)
Query Neighborhood Hits	99	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNB1_MOUSE
NC score	0.750006 (rank : 35)	θ value	2.35696e-16 (rank : 29)
Query Neighborhood Hits	99	Target Neighborhood Hits	154	Shared Neighborhood Hits	77
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.749933 (rank : 36)	θ value	2.35696e-16 (rank : 28)
Query Neighborhood Hits	99	Target Neighborhood Hits	169	Shared Neighborhood Hits	78
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNF1_HUMAN
NC score	0.749887 (rank : 37)	θ value	7.09661e-13 (rank : 39)
Query Neighborhood Hits	99	Target Neighborhood Hits	109	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNS3_HUMAN
NC score	0.749248 (rank : 38)	θ value	1.52774e-15 (rank : 35)
Query Neighborhood Hits	99	Target Neighborhood Hits	125	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNG4_HUMAN
NC score	0.744189 (rank : 39)	θ value	8.38298e-14 (rank : 37)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNG1_HUMAN
NC score	0.742602 (rank : 40)	θ value	3.52202e-12 (rank : 41)
Query Neighborhood Hits	99	Target Neighborhood Hits	103	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNG3_HUMAN
NC score	0.738169 (rank : 41)	θ value	3.29651e-10 (rank : 44)
Query Neighborhood Hits	99	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.736971 (rank : 42)	θ value	2.52405e-10 (rank : 43)
Query Neighborhood Hits	99	Target Neighborhood Hits	91	Shared Neighborhood Hits	63
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNV2_HUMAN
NC score	0.732120 (rank : 43)	θ value	1.09485e-13 (rank : 38)
Query Neighborhood Hits	99	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNS1_HUMAN
NC score	0.731974 (rank : 44)	θ value	1.133e-10 (rank : 42)
Query Neighborhood Hits	99	Target Neighborhood Hits	116	Shared Neighborhood Hits	69
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNS2_MOUSE
NC score	0.731684 (rank : 45)	θ value	3.29651e-10 (rank : 46)
Query Neighborhood Hits	99	Target Neighborhood Hits	130	Shared Neighborhood Hits	75
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
NC score	0.731277 (rank : 46)	θ value	3.29651e-10 (rank : 45)
Query Neighborhood Hits	99	Target Neighborhood Hits	129	Shared Neighborhood Hits	75
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS1_MOUSE
NC score	0.728445 (rank : 47)	θ value	1.25267e-09 (rank : 47)
Query Neighborhood Hits	99	Target Neighborhood Hits	114	Shared Neighborhood Hits	76
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNN4_MOUSE
NC score	0.443723 (rank : 48)	θ value	6.87365e-08 (rank : 48)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	70
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNN4_HUMAN
NC score	0.437071 (rank : 49)	θ value	1.17247e-07 (rank : 49)
Query Neighborhood Hits	99	Target Neighborhood Hits	90	Shared Neighborhood Hits	70
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCMA1_MOUSE
NC score	0.426488 (rank : 50)	θ value	0.0193708 (rank : 56)
Query Neighborhood Hits	99	Target Neighborhood Hits	94	Shared Neighborhood Hits	68
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.425665 (rank : 51)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	68
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNN1_HUMAN
NC score	0.346154 (rank : 52)	θ value	0.00035302 (rank : 50)
Query Neighborhood Hits	99	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_MOUSE
NC score	0.342836 (rank : 53)	θ value	0.00298849 (rank : 51)
Query Neighborhood Hits	99	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN2_HUMAN
NC score	0.342824 (rank : 54)	θ value	0.00509761 (rank : 52)
Query Neighborhood Hits	99	Target Neighborhood Hits	117	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.342798 (rank : 55)	θ value	0.00509761 (rank : 53)
Query Neighborhood Hits	99	Target Neighborhood Hits	120	Shared Neighborhood Hits	68
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_HUMAN
NC score	0.339069 (rank : 56)	θ value	0.00665767 (rank : 54)
Query Neighborhood Hits	99	Target Neighborhood Hits	216	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
NC score	0.331766 (rank : 57)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	99	Target Neighborhood Hits	171	Shared Neighborhood Hits	69
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCNKA_HUMAN
NC score	0.208798 (rank : 58)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	99	Target Neighborhood Hits	111	Shared Neighborhood Hits	70
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKH_HUMAN
NC score	0.184522 (rank : 59)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	99	Target Neighborhood Hits	89	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNKF_HUMAN
NC score	0.179357 (rank : 60)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	99	Target Neighborhood Hits	87	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNT1_HUMAN
NC score	0.175104 (rank : 61)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	99	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNKG_HUMAN
NC score	0.170937 (rank : 62)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	99	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK6_HUMAN
NC score	0.170147 (rank : 63)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	99	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCTD1_HUMAN
NC score	0.166186 (rank : 64)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	99	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q719H9	Gene names	KCTD1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD1_MOUSE
NC score	0.166186 (rank : 65)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	99	Target Neighborhood Hits	74	Shared Neighborhood Hits	37
SwissProt Accessions	Q5M956, Q5EER9	Gene names	Kctd1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD6_MOUSE
NC score	0.162672 (rank : 66)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BNL5, Q3TXX1	Gene names	Kctd6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD6_HUMAN
NC score	0.161046 (rank : 67)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NC69, Q8NBS6, Q8TCA6	Gene names	KCTD6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCNK3_HUMAN
NC score	0.160269 (rank : 68)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	99	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.160222 (rank : 69)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	99	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCD15_HUMAN
NC score	0.159420 (rank : 70)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	99	Target Neighborhood Hits	76	Shared Neighborhood Hits	37
SwissProt Accessions	Q96SI1, Q9BVI6	Gene names	KCTD15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCNK5_HUMAN
NC score	0.154596 (rank : 71)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	99	Target Neighborhood Hits	102	Shared Neighborhood Hits	69
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCD15_MOUSE
NC score	0.153772 (rank : 72)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	99	Target Neighborhood Hits	78	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K0E1	Gene names	Kctd15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCTD4_MOUSE
NC score	0.150530 (rank : 73)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	99	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D7X1, Q8CCQ3, Q9CYK4	Gene names	Kctd4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD4_HUMAN
NC score	0.149766 (rank : 74)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	99	Target Neighborhood Hits	72	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WVF5	Gene names	KCTD4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCNK2_MOUSE
NC score	0.146804 (rank : 75)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	99	Target Neighborhood Hits	88	Shared Neighborhood Hits	62
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCTD2_HUMAN
NC score	0.143098 (rank : 76)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	99	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCNK2_HUMAN
NC score	0.142786 (rank : 77)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	99	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCTD7_MOUSE
NC score	0.142103 (rank : 78)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	99	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCTD3_HUMAN
NC score	0.138788 (rank : 79)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	99	Target Neighborhood Hits	90	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

KCTD5_MOUSE
NC score	0.134096 (rank : 80)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	99	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD5_HUMAN
NC score	0.132044 (rank : 81)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	99	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD3_MOUSE
NC score	0.127961 (rank : 82)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BFX3, Q6P7X4	Gene names	Kctd3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3.

KCTD7_HUMAN
NC score	0.125980 (rank : 83)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	99	Target Neighborhood Hits	74	Shared Neighborhood Hits	28
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCNK9_HUMAN
NC score	0.125164 (rank : 84)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	99	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
NC score	0.124365 (rank : 85)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	99	Target Neighborhood Hits	86	Shared Neighborhood Hits	61
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNRG_HUMAN
NC score	0.122294 (rank : 86)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	99	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N5I3, Q8IU75, Q8N3Q9	Gene names	KCNRG, CLLD4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCNK4_MOUSE
NC score	0.119950 (rank : 87)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	99	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNRG_MOUSE
NC score	0.116379 (rank : 88)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	99	Target Neighborhood Hits	68	Shared Neighborhood Hits	30
SwissProt Accessions	Q2TUM3, Q6P8J6, Q8C6V1	Gene names	Kcnrg, Clld4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCNT1_MOUSE
NC score	0.102593 (rank : 89)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	99	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCD17_HUMAN
NC score	0.101902 (rank : 90)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

SC11A_HUMAN
NC score	0.099287 (rank : 91)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	99	Target Neighborhood Hits	111	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

CAC1H_MOUSE
NC score	0.093499 (rank : 92)	θ value	0.21417 (rank : 61)
Query Neighborhood Hits	99	Target Neighborhood Hits	230	Shared Neighborhood Hits	43
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

KCNK4_HUMAN
NC score	0.093349 (rank : 93)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	99	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCD14_HUMAN
NC score	0.090834 (rank : 94)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	99	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BQ13	Gene names	KCTD14
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD14.

CAC1I_HUMAN
NC score	0.089468 (rank : 95)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	99	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

SC11A_MOUSE
NC score	0.089163 (rank : 96)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	99	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

KCTD9_MOUSE
NC score	0.088401 (rank : 97)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	99	Target Neighborhood Hits	63	Shared Neighborhood Hits	24
SwissProt Accessions	Q80UN1	Gene names	Kctd9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

SCN4A_HUMAN
NC score	0.087535 (rank : 98)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

CAC1H_HUMAN
NC score	0.086902 (rank : 99)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	99	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

KCTD9_HUMAN
NC score	0.086045 (rank : 100)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L273, Q6NUM8, Q9NXV4	Gene names	KCTD9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCNK1_HUMAN
NC score	0.079856 (rank : 101)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	99	Target Neighborhood Hits	68	Shared Neighborhood Hits	43
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
NC score	0.078019 (rank : 102)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	99	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK7_MOUSE
NC score	0.077415 (rank : 103)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	99	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK7_HUMAN
NC score	0.075671 (rank : 104)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	99	Target Neighborhood Hits	42	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

SCN8A_HUMAN
NC score	0.073582 (rank : 105)	θ value	0.0431538 (rank : 58)
Query Neighborhood Hits	99	Target Neighborhood Hits	135	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.073361 (rank : 106)	θ value	0.0431538 (rank : 59)
Query Neighborhood Hits	99	Target Neighborhood Hits	136	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1B_MOUSE
NC score	0.072602 (rank : 107)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	99	Target Neighborhood Hits	351	Shared Neighborhood Hits	39
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1G_HUMAN
NC score	0.070960 (rank : 108)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	99	Target Neighborhood Hits	587	Shared Neighborhood Hits	37
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CAC1A_MOUSE
NC score	0.070809 (rank : 109)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	99	Target Neighborhood Hits	267	Shared Neighborhood Hits	43
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_HUMAN
NC score	0.070663 (rank : 110)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	99	Target Neighborhood Hits	387	Shared Neighborhood Hits	44
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1F_MOUSE
NC score	0.069524 (rank : 111)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	99	Target Neighborhood Hits	142	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.068665 (rank : 112)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	99	Target Neighborhood Hits	141	Shared Neighborhood Hits	35
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1C_HUMAN
NC score	0.068252 (rank : 113)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	99	Target Neighborhood Hits	158	Shared Neighborhood Hits	34
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CAC1C_MOUSE
NC score	0.068017 (rank : 114)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	99	Target Neighborhood Hits	130	Shared Neighborhood Hits	30
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SC10A_MOUSE
NC score	0.067859 (rank : 115)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	99	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1S_MOUSE
NC score	0.065992 (rank : 116)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	99	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1B_HUMAN
NC score	0.065096 (rank : 117)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	99	Target Neighborhood Hits	257	Shared Neighborhood Hits	36
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1D_HUMAN
NC score	0.063882 (rank : 118)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	99	Target Neighborhood Hits	118	Shared Neighborhood Hits	35
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

SCN9A_HUMAN
NC score	0.063414 (rank : 119)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	99	Target Neighborhood Hits	157	Shared Neighborhood Hits	32
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SC10A_HUMAN
NC score	0.062905 (rank : 120)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	99	Target Neighborhood Hits	116	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CAC1S_HUMAN
NC score	0.062018 (rank : 121)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	99	Target Neighborhood Hits	92	Shared Neighborhood Hits	32
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

SCN3A_HUMAN
NC score	0.059853 (rank : 122)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	99	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN5A_HUMAN
NC score	0.059465 (rank : 123)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	99	Target Neighborhood Hits	145	Shared Neighborhood Hits	31
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1E_HUMAN
NC score	0.059175 (rank : 124)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	99	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

KCNKC_HUMAN
NC score	0.058365 (rank : 125)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	99	Target Neighborhood Hits	51	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

CAC1E_MOUSE
NC score	0.057649 (rank : 126)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	99	Target Neighborhood Hits	167	Shared Neighborhood Hits	29
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN1A_HUMAN
NC score	0.056032 (rank : 127)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	99	Target Neighborhood Hits	148	Shared Neighborhood Hits	29
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN7A_HUMAN
NC score	0.055557 (rank : 128)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	99	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SCN2A_HUMAN
NC score	0.054953 (rank : 129)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	99	Target Neighborhood Hits	157	Shared Neighborhood Hits	28
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

KCD11_MOUSE
NC score	0.054021 (rank : 130)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	99	Target Neighborhood Hits	47	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K485	Gene names	Kctd11, Ren
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCTD2_MOUSE
NC score	0.052781 (rank : 131)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	99	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CEZ0	Gene names	Kctd2
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCTD8_MOUSE
NC score	0.052689 (rank : 132)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	99	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	Q50H33, Q8BR74, Q8C4C2, Q8C906, Q8C9B0, Q8CAA9	Gene names	Kctd8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCD11_HUMAN
NC score	0.052319 (rank : 133)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	99	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q693B1	Gene names	KCTD11, REN
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

JIP4_HUMAN
NC score	0.020155 (rank : 134)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	99	Target Neighborhood Hits	585	Shared Neighborhood Hits	7
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

JIP4_MOUSE
NC score	0.017159 (rank : 135)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	99	Target Neighborhood Hits	593	Shared Neighborhood Hits	6
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

NDUAB_MOUSE
NC score	0.016106 (rank : 136)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	99	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8B4	Gene names	Ndufa11
Domain Architecture	No domain graphic available
Description	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (EC 1.6.5.3) (EC 1.6.99.3) (NADH-ubiquinone oxidoreductase subunit B14.7) (Complex I-B14.7) (CI-B14.7).

SNP25_HUMAN
NC score	0.011230 (rank : 137)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P60880, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	SNAP25, SNAP
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

SNP25_MOUSE
NC score	0.011230 (rank : 138)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	99	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	P60879, P13795, P36974, P70557, P70558, Q8IXK3, Q96FM2, Q9BR45	Gene names	Snap25, Snap
Domain Architecture
Description	Synaptosomal-associated protein 25 (SNAP-25) (Synaptosomal-associated 25 kDa protein) (Super protein) (SUP).

NRX2B_HUMAN
NC score	0.008380 (rank : 139)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	99	Target Neighborhood Hits	481	Shared Neighborhood Hits	8
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

TSC2_HUMAN
NC score	0.005551 (rank : 140)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	99	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

MYCL1_MOUSE
NC score	0.005497 (rank : 141)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	99	Target Neighborhood Hits	123	Shared Neighborhood Hits	2
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NRX2A_HUMAN
NC score	0.004674 (rank : 142)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	99	Target Neighborhood Hits	614	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PCLO_HUMAN
NC score	0.004263 (rank : 143)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	99	Target Neighborhood Hits	2046	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

STX2_HUMAN
NC score	0.003711 (rank : 144)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	99	Target Neighborhood Hits	158	Shared Neighborhood Hits	2
SwissProt Accessions	P32856, Q86VW8	Gene names	STX2, EPIM
Domain Architecture
Description	Syntaxin-2 (Epimorphin).

SKIL_HUMAN
NC score	0.002312 (rank : 145)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	99	Target Neighborhood Hits	460	Shared Neighborhood Hits	5
SwissProt Accessions	P12757, O00464, P12756, Q07501	Gene names	SKIL, SNO
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

MAGI2_MOUSE
NC score	0.002158 (rank : 146)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	99	Target Neighborhood Hits	370	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVQ1, Q3UH81, Q6GT88, Q8BYT1, Q8CA85	Gene names	Magi2, Acvrinp1, Aip1, Arip1
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Activin receptor-interacting protein 1) (Acvrip1).

MAGI2_HUMAN
NC score	0.001926 (rank : 147)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	99	Target Neighborhood Hits	373	Shared Neighborhood Hits	3
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MAP1A_HUMAN
NC score	-0.000122 (rank : 148)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	99	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

HXA4_MOUSE
NC score	-0.000627 (rank : 149)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	99	Target Neighborhood Hits	379	Shared Neighborhood Hits	6
SwissProt Accessions	P06798, Q61684, Q64388, Q8BPE6	Gene names	Hoxa4, Hox-1.4, Hoxa-4
Domain Architecture
Description	Homeobox protein Hox-A4 (Hox-1.4) (Homeobox protein MH-3).

RX_MOUSE
NC score	-0.000931 (rank : 150)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	99	Target Neighborhood Hits	429	Shared Neighborhood Hits	5
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

P2RY2_MOUSE
NC score	-0.000938 (rank : 151)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	99	Target Neighborhood Hits	476	Shared Neighborhood Hits	3
SwissProt Accessions	P35383, O09031, Q9CPZ4	Gene names	P2ry2, P2ru1
Domain Architecture
Description	P2Y purinoceptor 2 (P2Y2) (P2U purinoceptor 1) (P2U1) (ATP receptor) (Purinergic receptor).

ZN687_HUMAN
NC score	-0.001151 (rank : 152)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	99	Target Neighborhood Hits	1244	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

CSKI2_MOUSE
NC score	-0.001886 (rank : 153)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	99	Target Neighborhood Hits	812	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.