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Network neighborhood for query Sequence : KCNC3_MOUSE

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KCNC3_MOUSE
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNC3_HUMAN
θ value	0 (rank : 1)	NC score	0.995350 (rank : 2)
Query Neighborhood Hits	173	Target Neighborhood Hits	256	Shared Neighborhood Hits	150
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC1_MOUSE
θ value	4.84403e-179 (rank : 3)	NC score	0.990789 (rank : 3)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	117
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
θ value	6.32649e-179 (rank : 4)	NC score	0.990686 (rank : 4)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	117
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_MOUSE
θ value	7.508e-164 (rank : 5)	NC score	0.987994 (rank : 6)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC4_HUMAN
θ value	2.85304e-163 (rank : 6)	NC score	0.989055 (rank : 5)
Query Neighborhood Hits	173	Target Neighborhood Hits	141	Shared Neighborhood Hits	114
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNF1_HUMAN
θ value	4.10295e-61 (rank : 7)	NC score	0.942290 (rank : 7)
Query Neighborhood Hits	173	Target Neighborhood Hits	109	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCND2_HUMAN
θ value	4.53632e-60 (rank : 8)	NC score	0.939084 (rank : 10)
Query Neighborhood Hits	173	Target Neighborhood Hits	154	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	4.53632e-60 (rank : 9)	NC score	0.938974 (rank : 11)
Query Neighborhood Hits	173	Target Neighborhood Hits	156	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
θ value	3.84025e-59 (rank : 10)	NC score	0.936444 (rank : 17)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	3.84025e-59 (rank : 11)	NC score	0.936838 (rank : 16)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNS2_MOUSE
θ value	6.55044e-59 (rank : 12)	NC score	0.937505 (rank : 14)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	110
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_HUMAN
θ value	1.90589e-58 (rank : 13)	NC score	0.937632 (rank : 13)
Query Neighborhood Hits	173	Target Neighborhood Hits	129	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNG3_HUMAN
θ value	7.75577e-52 (rank : 14)	NC score	0.941521 (rank : 8)
Query Neighborhood Hits	173	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNB1_HUMAN
θ value	1.72781e-51 (rank : 15)	NC score	0.934117 (rank : 19)
Query Neighborhood Hits	173	Target Neighborhood Hits	169	Shared Neighborhood Hits	111
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	1.72781e-51 (rank : 16)	NC score	0.934733 (rank : 18)
Query Neighborhood Hits	173	Target Neighborhood Hits	154	Shared Neighborhood Hits	111
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNG3_MOUSE
θ value	2.94719e-51 (rank : 17)	NC score	0.941188 (rank : 9)
Query Neighborhood Hits	173	Target Neighborhood Hits	91	Shared Neighborhood Hits	83
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNA6_MOUSE
θ value	8.57503e-51 (rank : 18)	NC score	0.925347 (rank : 27)
Query Neighborhood Hits	173	Target Neighborhood Hits	106	Shared Neighborhood Hits	90
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNB2_HUMAN
θ value	9.48078e-50 (rank : 19)	NC score	0.932190 (rank : 21)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	113
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNA6_HUMAN
θ value	1.23823e-49 (rank : 20)	NC score	0.925388 (rank : 26)
Query Neighborhood Hits	173	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA4_HUMAN
θ value	1.73182e-43 (rank : 21)	NC score	0.921788 (rank : 32)
Query Neighborhood Hits	173	Target Neighborhood Hits	108	Shared Neighborhood Hits	84
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNV2_HUMAN
θ value	2.95404e-43 (rank : 22)	NC score	0.937381 (rank : 15)
Query Neighborhood Hits	173	Target Neighborhood Hits	137	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNA1_HUMAN
θ value	3.85808e-43 (rank : 23)	NC score	0.921851 (rank : 31)
Query Neighborhood Hits	173	Target Neighborhood Hits	104	Shared Neighborhood Hits	91
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA4_MOUSE
θ value	6.58091e-43 (rank : 24)	NC score	0.922183 (rank : 29)
Query Neighborhood Hits	173	Target Neighborhood Hits	98	Shared Neighborhood Hits	83
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA1_MOUSE
θ value	8.59492e-43 (rank : 25)	NC score	0.921861 (rank : 30)
Query Neighborhood Hits	173	Target Neighborhood Hits	103	Shared Neighborhood Hits	92
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA3_MOUSE
θ value	1.91475e-42 (rank : 26)	NC score	0.920151 (rank : 34)
Query Neighborhood Hits	173	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA3_HUMAN
θ value	4.2656e-42 (rank : 27)	NC score	0.920673 (rank : 33)
Query Neighborhood Hits	173	Target Neighborhood Hits	101	Shared Neighborhood Hits	89
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNG1_HUMAN
θ value	2.11701e-41 (rank : 28)	NC score	0.932219 (rank : 20)
Query Neighborhood Hits	173	Target Neighborhood Hits	103	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCND1_HUMAN
θ value	4.71619e-41 (rank : 29)	NC score	0.931643 (rank : 23)
Query Neighborhood Hits	173	Target Neighborhood Hits	160	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
θ value	1.79215e-40 (rank : 30)	NC score	0.930131 (rank : 24)
Query Neighborhood Hits	173	Target Neighborhood Hits	165	Shared Neighborhood Hits	119
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNA5_HUMAN
θ value	8.89434e-40 (rank : 31)	NC score	0.918021 (rank : 35)
Query Neighborhood Hits	173	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNS3_HUMAN
θ value	1.16164e-39 (rank : 32)	NC score	0.938166 (rank : 12)
Query Neighborhood Hits	173	Target Neighborhood Hits	125	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNA5_MOUSE
θ value	2.86122e-38 (rank : 33)	NC score	0.917472 (rank : 36)
Query Neighborhood Hits	173	Target Neighborhood Hits	119	Shared Neighborhood Hits	91
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNS1_HUMAN
θ value	3.73686e-38 (rank : 34)	NC score	0.932142 (rank : 22)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	99
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNA2_MOUSE
θ value	4.88048e-38 (rank : 35)	NC score	0.915031 (rank : 38)
Query Neighborhood Hits	173	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
θ value	8.32485e-38 (rank : 36)	NC score	0.914776 (rank : 39)
Query Neighborhood Hits	173	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNS1_MOUSE
θ value	1.01765e-35 (rank : 37)	NC score	0.929968 (rank : 25)
Query Neighborhood Hits	173	Target Neighborhood Hits	114	Shared Neighborhood Hits	97
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG4_HUMAN
θ value	1.57365e-28 (rank : 38)	NC score	0.923268 (rank : 28)
Query Neighborhood Hits	173	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNG2_HUMAN
θ value	8.08199e-25 (rank : 39)	NC score	0.915275 (rank : 37)
Query Neighborhood Hits	173	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNQ1_HUMAN
θ value	4.02038e-16 (rank : 40)	NC score	0.752179 (rank : 40)
Query Neighborhood Hits	173	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
θ value	4.02038e-16 (rank : 41)	NC score	0.725138 (rank : 42)
Query Neighborhood Hits	173	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	4.02038e-16 (rank : 42)	NC score	0.724277 (rank : 43)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ1_MOUSE
θ value	5.25075e-16 (rank : 43)	NC score	0.744790 (rank : 41)
Query Neighborhood Hits	173	Target Neighborhood Hits	175	Shared Neighborhood Hits	79
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ5_HUMAN
θ value	5.8054e-15 (rank : 44)	NC score	0.712925 (rank : 44)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ4_HUMAN
θ value	4.16044e-13 (rank : 45)	NC score	0.706812 (rank : 45)
Query Neighborhood Hits	173	Target Neighborhood Hits	136	Shared Neighborhood Hits	82
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ3_HUMAN
θ value	5.43371e-13 (rank : 46)	NC score	0.684019 (rank : 47)
Query Neighborhood Hits	173	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	5.43371e-13 (rank : 47)	NC score	0.685269 (rank : 46)
Query Neighborhood Hits	173	Target Neighborhood Hits	105	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCTD3_HUMAN
θ value	2.44474e-05 (rank : 48)	NC score	0.318386 (rank : 59)
Query Neighborhood Hits	173	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

KCMA1_HUMAN
θ value	0.000121331 (rank : 49)	NC score	0.466932 (rank : 49)
Query Neighborhood Hits	173	Target Neighborhood Hits	96	Shared Neighborhood Hits	70
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	0.000121331 (rank : 50)	NC score	0.467845 (rank : 48)
Query Neighborhood Hits	173	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCD14_HUMAN
θ value	0.00020696 (rank : 51)	NC score	0.269593 (rank : 68)
Query Neighborhood Hits	173	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BQ13	Gene names	KCTD14
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD14.

KCTD4_MOUSE
θ value	0.00020696 (rank : 52)	NC score	0.329960 (rank : 55)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D7X1, Q8CCQ3, Q9CYK4	Gene names	Kctd4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD8_MOUSE
θ value	0.00020696 (rank : 53)	NC score	0.190954 (rank : 81)
Query Neighborhood Hits	173	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q50H33, Q8BR74, Q8C4C2, Q8C906, Q8C9B0, Q8CAA9	Gene names	Kctd8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCTD4_HUMAN
θ value	0.000270298 (rank : 54)	NC score	0.327935 (rank : 56)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WVF5	Gene names	KCTD4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD5_MOUSE
θ value	0.000461057 (rank : 55)	NC score	0.313280 (rank : 60)
Query Neighborhood Hits	173	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD3_MOUSE
θ value	0.00102713 (rank : 56)	NC score	0.299986 (rank : 64)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BFX3, Q6P7X4	Gene names	Kctd3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3.

KCNRG_MOUSE
θ value	0.00175202 (rank : 57)	NC score	0.293517 (rank : 66)
Query Neighborhood Hits	173	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q2TUM3, Q6P8J6, Q8C6V1	Gene names	Kcnrg, Clld4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCD15_HUMAN
θ value	0.00228821 (rank : 58)	NC score	0.334939 (rank : 52)
Query Neighborhood Hits	173	Target Neighborhood Hits	76	Shared Neighborhood Hits	64
SwissProt Accessions	Q96SI1, Q9BVI6	Gene names	KCTD15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCTD5_HUMAN
θ value	0.00228821 (rank : 59)	NC score	0.309611 (rank : 61)
Query Neighborhood Hits	173	Target Neighborhood Hits	66	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD8_HUMAN
θ value	0.00228821 (rank : 60)	NC score	0.179665 (rank : 82)
Query Neighborhood Hits	173	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZWB6	Gene names	KCTD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

SC11A_HUMAN
θ value	0.00228821 (rank : 61)	NC score	0.170685 (rank : 84)
Query Neighborhood Hits	173	Target Neighborhood Hits	111	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

KCD15_MOUSE
θ value	0.00509761 (rank : 62)	NC score	0.324683 (rank : 57)
Query Neighborhood Hits	173	Target Neighborhood Hits	78	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0E1	Gene names	Kctd15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCTD2_HUMAN
θ value	0.00665767 (rank : 63)	NC score	0.318850 (rank : 58)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCNT1_HUMAN
θ value	0.00869519 (rank : 64)	NC score	0.243055 (rank : 77)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCTD1_HUMAN
θ value	0.0148317 (rank : 65)	NC score	0.339988 (rank : 50)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	Q719H9	Gene names	KCTD1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD1_MOUSE
θ value	0.0148317 (rank : 66)	NC score	0.339988 (rank : 51)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	Q5M956, Q5EER9	Gene names	Kctd1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD6_HUMAN
θ value	0.0148317 (rank : 67)	NC score	0.330346 (rank : 54)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NC69, Q8NBS6, Q8TCA6	Gene names	KCTD6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD6_MOUSE
θ value	0.0148317 (rank : 68)	NC score	0.333771 (rank : 53)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BNL5, Q3TXX1	Gene names	Kctd6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

CAC1F_MOUSE
θ value	0.0193708 (rank : 69)	NC score	0.129875 (rank : 105)
Query Neighborhood Hits	173	Target Neighborhood Hits	142	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
θ value	0.0330416 (rank : 70)	NC score	0.128960 (rank : 106)
Query Neighborhood Hits	173	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

EP300_HUMAN
θ value	0.0431538 (rank : 71)	NC score	0.024155 (rank : 145)
Query Neighborhood Hits	173	Target Neighborhood Hits	821	Shared Neighborhood Hits	35
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CIC_HUMAN
θ value	0.0563607 (rank : 72)	NC score	0.018112 (rank : 151)
Query Neighborhood Hits	173	Target Neighborhood Hits	992	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

KCNRG_HUMAN
θ value	0.0563607 (rank : 73)	NC score	0.296145 (rank : 65)
Query Neighborhood Hits	173	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N5I3, Q8IU75, Q8N3Q9	Gene names	KCNRG, CLLD4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

SC10A_MOUSE
θ value	0.0563607 (rank : 74)	NC score	0.124903 (rank : 107)
Query Neighborhood Hits	173	Target Neighborhood Hits	107	Shared Neighborhood Hits	52
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

SC11A_MOUSE
θ value	0.0563607 (rank : 75)	NC score	0.153071 (rank : 92)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

KCNT1_MOUSE
θ value	0.0736092 (rank : 76)	NC score	0.157987 (rank : 89)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCTD9_MOUSE
θ value	0.0736092 (rank : 77)	NC score	0.233207 (rank : 78)
Query Neighborhood Hits	173	Target Neighborhood Hits	63	Shared Neighborhood Hits	51
SwissProt Accessions	Q80UN1	Gene names	Kctd9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

CAC1H_MOUSE
θ value	0.0961366 (rank : 78)	NC score	0.155417 (rank : 90)
Query Neighborhood Hits	173	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

MTSS1_MOUSE
θ value	0.0961366 (rank : 79)	NC score	0.037019 (rank : 143)
Query Neighborhood Hits	173	Target Neighborhood Hits	592	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

CAC1H_HUMAN
θ value	0.125558 (rank : 80)	NC score	0.151518 (rank : 94)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	59
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

KCD16_MOUSE
θ value	0.163984 (rank : 81)	NC score	0.163836 (rank : 86)
Query Neighborhood Hits	173	Target Neighborhood Hits	58	Shared Neighborhood Hits	42
SwissProt Accessions	Q5DTY9, Q78Y50	Gene names	Kctd16, Kiaa1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCD17_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.252601 (rank : 73)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

MTSS1_HUMAN
θ value	0.163984 (rank : 83)	NC score	0.037626 (rank : 142)
Query Neighborhood Hits	173	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CD248_HUMAN
θ value	0.21417 (rank : 84)	NC score	0.012213 (rank : 158)
Query Neighborhood Hits	173	Target Neighborhood Hits	679	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CEBPE_HUMAN
θ value	0.21417 (rank : 85)	NC score	0.023055 (rank : 147)
Query Neighborhood Hits	173	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

KCD16_HUMAN
θ value	0.21417 (rank : 86)	NC score	0.159063 (rank : 87)
Query Neighborhood Hits	173	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q68DU8, Q9P2M9	Gene names	KCTD16, KIAA1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCNKA_HUMAN
θ value	0.21417 (rank : 87)	NC score	0.206518 (rank : 80)
Query Neighborhood Hits	173	Target Neighborhood Hits	111	Shared Neighborhood Hits	67
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNN2_HUMAN
θ value	0.21417 (rank : 88)	NC score	0.258265 (rank : 70)
Query Neighborhood Hits	173	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	0.21417 (rank : 89)	NC score	0.258264 (rank : 71)
Query Neighborhood Hits	173	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_HUMAN
θ value	0.21417 (rank : 90)	NC score	0.252754 (rank : 72)
Query Neighborhood Hits	173	Target Neighborhood Hits	216	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
θ value	0.21417 (rank : 91)	NC score	0.251195 (rank : 74)
Query Neighborhood Hits	173	Target Neighborhood Hits	171	Shared Neighborhood Hits	69
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCTD9_HUMAN
θ value	0.21417 (rank : 92)	NC score	0.227045 (rank : 79)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q7L273, Q6NUM8, Q9NXV4	Gene names	KCTD9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

CAC1I_HUMAN
θ value	0.279714 (rank : 93)	NC score	0.152126 (rank : 93)
Query Neighborhood Hits	173	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

KCNN1_HUMAN
θ value	0.279714 (rank : 94)	NC score	0.247046 (rank : 76)
Query Neighborhood Hits	173	Target Neighborhood Hits	125	Shared Neighborhood Hits	65
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_MOUSE
θ value	0.279714 (rank : 95)	NC score	0.248264 (rank : 75)
Query Neighborhood Hits	173	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

PSL1_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.019833 (rank : 149)
Query Neighborhood Hits	173	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RECQ5_HUMAN
θ value	0.279714 (rank : 97)	NC score	0.016104 (rank : 154)
Query Neighborhood Hits	173	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

SCN4A_HUMAN
θ value	0.279714 (rank : 98)	NC score	0.150766 (rank : 95)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	65
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

SCN5A_HUMAN
θ value	0.279714 (rank : 99)	NC score	0.119350 (rank : 113)
Query Neighborhood Hits	173	Target Neighborhood Hits	145	Shared Neighborhood Hits	49
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

CAC1S_MOUSE
θ value	0.365318 (rank : 100)	NC score	0.113366 (rank : 120)
Query Neighborhood Hits	173	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

KCD12_HUMAN
θ value	0.365318 (rank : 101)	NC score	0.154861 (rank : 91)
Query Neighborhood Hits	173	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCTD7_HUMAN
θ value	0.47712 (rank : 102)	NC score	0.261886 (rank : 69)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	55
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCTD7_MOUSE
θ value	0.47712 (rank : 103)	NC score	0.281901 (rank : 67)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCD12_MOUSE
θ value	0.62314 (rank : 104)	NC score	0.148792 (rank : 97)
Query Neighborhood Hits	173	Target Neighborhood Hits	66	Shared Neighborhood Hits	41
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

SCN8A_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.115535 (rank : 115)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.116003 (rank : 114)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

CAC1S_HUMAN
θ value	0.813845 (rank : 107)	NC score	0.112727 (rank : 121)
Query Neighborhood Hits	173	Target Neighborhood Hits	92	Shared Neighborhood Hits	49
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

E2F4_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.016646 (rank : 152)
Query Neighborhood Hits	173	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

MELPH_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.012925 (rank : 157)
Query Neighborhood Hits	173	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

BAT2_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.023918 (rank : 146)
Query Neighborhood Hits	173	Target Neighborhood Hits	947	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

RGS3_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.008285 (rank : 167)
Query Neighborhood Hits	173	Target Neighborhood Hits	1375	Shared Neighborhood Hits	26
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SCN8A_MOUSE
θ value	1.06291 (rank : 112)	NC score	0.114527 (rank : 116)
Query Neighborhood Hits	173	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

DIDO1_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.014596 (rank : 155)
Query Neighborhood Hits	173	Target Neighborhood Hits	960	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

KCNK2_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.135021 (rank : 102)
Query Neighborhood Hits	173	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNKH_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.175936 (rank : 83)
Query Neighborhood Hits	173	Target Neighborhood Hits	89	Shared Neighborhood Hits	62
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

PLCB2_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.004010 (rank : 178)
Query Neighborhood Hits	173	Target Neighborhood Hits	608	Shared Neighborhood Hits	9
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

PRDM1_HUMAN
θ value	1.38821 (rank : 117)	NC score	-0.004585 (rank : 193)
Query Neighborhood Hits	173	Target Neighborhood Hits	734	Shared Neighborhood Hits	5
SwissProt Accessions	O75626	Gene names	PRDM1, BLIMP1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1) (Positive regulatory domain I-binding factor 1) (PRDI- binding factor 1) (PRDI-BF1).

SPEG_MOUSE
θ value	1.38821 (rank : 118)	NC score	-0.003242 (rank : 190)
Query Neighborhood Hits	173	Target Neighborhood Hits	1959	Shared Neighborhood Hits	36
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

BAZ2A_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.006704 (rank : 173)
Query Neighborhood Hits	173	Target Neighborhood Hits	780	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BCL9_HUMAN
θ value	1.81305 (rank : 120)	NC score	0.008820 (rank : 166)
Query Neighborhood Hits	173	Target Neighborhood Hits	1008	Shared Neighborhood Hits	29
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

IRK13_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.011655 (rank : 159)
Query Neighborhood Hits	173	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

KCNK2_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.130772 (rank : 104)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

SCN3A_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.113564 (rank : 119)
Query Neighborhood Hits	173	Target Neighborhood Hits	115	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

ATX7_MOUSE
θ value	2.36792 (rank : 124)	NC score	0.019759 (rank : 150)
Query Neighborhood Hits	173	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CEL_HUMAN
θ value	2.36792 (rank : 125)	NC score	0.007637 (rank : 169)
Query Neighborhood Hits	173	Target Neighborhood Hits	896	Shared Neighborhood Hits	25
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CRIM1_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.002326 (rank : 181)
Query Neighborhood Hits	173	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

IF4B_MOUSE
θ value	2.36792 (rank : 127)	NC score	0.009340 (rank : 165)
Query Neighborhood Hits	173	Target Neighborhood Hits	368	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IRF3_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.009801 (rank : 162)
Query Neighborhood Hits	173	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

KCNKF_HUMAN
θ value	2.36792 (rank : 129)	NC score	0.165716 (rank : 85)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

TBCD1_HUMAN
θ value	2.36792 (rank : 130)	NC score	0.005105 (rank : 177)
Query Neighborhood Hits	173	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

CAC1A_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.124845 (rank : 108)
Query Neighborhood Hits	173	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1A_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.123641 (rank : 110)
Query Neighborhood Hits	173	Target Neighborhood Hits	267	Shared Neighborhood Hits	62
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1D_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.121572 (rank : 111)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CD2_HUMAN
θ value	3.0926 (rank : 134)	NC score	0.016350 (rank : 153)
Query Neighborhood Hits	173	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

COIA1_HUMAN
θ value	3.0926 (rank : 135)	NC score	0.006757 (rank : 172)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	24
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

DLG5_HUMAN
θ value	3.0926 (rank : 136)	NC score	-0.000285 (rank : 186)
Query Neighborhood Hits	173	Target Neighborhood Hits	1088	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

GR65_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.014528 (rank : 156)
Query Neighborhood Hits	173	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

HXB3_HUMAN
θ value	3.0926 (rank : 138)	NC score	-0.000083 (rank : 185)
Query Neighborhood Hits	173	Target Neighborhood Hits	559	Shared Neighborhood Hits	12
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

K2027_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.010050 (rank : 161)
Query Neighborhood Hits	173	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

KCNK3_HUMAN
θ value	3.0926 (rank : 140)	NC score	0.142870 (rank : 101)
Query Neighborhood Hits	173	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
θ value	3.0926 (rank : 141)	NC score	0.143376 (rank : 100)
Query Neighborhood Hits	173	Target Neighborhood Hits	93	Shared Neighborhood Hits	65
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

NCOR2_MOUSE
θ value	3.0926 (rank : 142)	NC score	0.007525 (rank : 170)
Query Neighborhood Hits	173	Target Neighborhood Hits	790	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SCAP_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.005445 (rank : 175)
Query Neighborhood Hits	173	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SIP1_MOUSE
θ value	3.0926 (rank : 144)	NC score	-0.005383 (rank : 194)
Query Neighborhood Hits	173	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

TARSH_HUMAN
θ value	3.0926 (rank : 145)	NC score	0.009627 (rank : 164)
Query Neighborhood Hits	173	Target Neighborhood Hits	768	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

BAT2_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.024659 (rank : 144)
Query Neighborhood Hits	173	Target Neighborhood Hits	931	Shared Neighborhood Hits	44
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

HXB3_MOUSE
θ value	4.03905 (rank : 147)	NC score	-0.000323 (rank : 187)
Query Neighborhood Hits	173	Target Neighborhood Hits	493	Shared Neighborhood Hits	8
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

KCNN4_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.300013 (rank : 63)
Query Neighborhood Hits	173	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNN4_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.302192 (rank : 62)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

CSKI2_MOUSE
θ value	5.27518 (rank : 150)	NC score	-0.001393 (rank : 188)
Query Neighborhood Hits	173	Target Neighborhood Hits	812	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

KCNK4_HUMAN
θ value	5.27518 (rank : 151)	NC score	0.067641 (rank : 135)
Query Neighborhood Hits	173	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK5_HUMAN
θ value	5.27518 (rank : 152)	NC score	0.134729 (rank : 103)
Query Neighborhood Hits	173	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNKG_HUMAN
θ value	5.27518 (rank : 153)	NC score	0.149624 (rank : 96)
Query Neighborhood Hits	173	Target Neighborhood Hits	90	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

PRGR_MOUSE
θ value	5.27518 (rank : 154)	NC score	0.000120 (rank : 184)
Query Neighborhood Hits	173	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SPR1A_MOUSE
θ value	5.27518 (rank : 155)	NC score	0.009652 (rank : 163)
Query Neighborhood Hits	173	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TXD11_HUMAN
θ value	5.27518 (rank : 156)	NC score	0.002741 (rank : 180)
Query Neighborhood Hits	173	Target Neighborhood Hits	402	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

WNK2_HUMAN
θ value	5.27518 (rank : 157)	NC score	-0.003725 (rank : 191)
Query Neighborhood Hits	173	Target Neighborhood Hits	1407	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

CAC1C_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.106282 (rank : 127)
Query Neighborhood Hits	173	Target Neighborhood Hits	158	Shared Neighborhood Hits	51
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

CF155_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.021889 (rank : 148)
Query Neighborhood Hits	173	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H8W2, Q5TG13	Gene names	C6orf155
Domain Architecture	No domain graphic available
Description	Protein C6orf155.

DCP1A_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.007863 (rank : 168)
Query Neighborhood Hits	173	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

LPP_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.002229 (rank : 182)
Query Neighborhood Hits	173	Target Neighborhood Hits	775	Shared Neighborhood Hits	18
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PTPRN_MOUSE
θ value	6.88961 (rank : 162)	NC score	0.000541 (rank : 183)
Query Neighborhood Hits	173	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RIMB1_MOUSE
θ value	6.88961 (rank : 163)	NC score	-0.004357 (rank : 192)
Query Neighborhood Hits	173	Target Neighborhood Hits	1376	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SC24A_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.006099 (rank : 174)
Query Neighborhood Hits	173	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SPR1A_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.011409 (rank : 160)
Query Neighborhood Hits	173	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

CAC1C_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.110432 (rank : 122)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

SCN1A_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.107204 (rank : 126)
Query Neighborhood Hits	173	Target Neighborhood Hits	148	Shared Neighborhood Hits	46
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN2A_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.102375 (rank : 128)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN7A_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.102305 (rank : 129)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	56
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

SON_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.005381 (rank : 176)
Query Neighborhood Hits	173	Target Neighborhood Hits	1568	Shared Neighborhood Hits	31
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPR1B_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.007457 (rank : 171)
Query Neighborhood Hits	173	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

TRIM7_HUMAN
θ value	8.99809 (rank : 172)	NC score	-0.001904 (rank : 189)
Query Neighborhood Hits	173	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TXLNB_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.003483 (rank : 179)
Query Neighborhood Hits	173	Target Neighborhood Hits	912	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

CAC1B_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.114240 (rank : 117)
Query Neighborhood Hits	173	Target Neighborhood Hits	257	Shared Neighborhood Hits	55
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1B_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.124078 (rank : 109)
Query Neighborhood Hits	173	Target Neighborhood Hits	351	Shared Neighborhood Hits	62
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1E_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.108877 (rank : 125)
Query Neighborhood Hits	173	Target Neighborhood Hits	148	Shared Neighborhood Hits	49
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1E_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.109356 (rank : 123)
Query Neighborhood Hits	173	Target Neighborhood Hits	167	Shared Neighborhood Hits	50
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CAC1G_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.119982 (rank : 112)
Query Neighborhood Hits	173	Target Neighborhood Hits	587	Shared Neighborhood Hits	62
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

KCD10_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.064429 (rank : 140)
Query Neighborhood Hits	173	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H3F6, Q53HN2, Q59FV1, Q6PL47, Q96SU0	Gene names	KCTD10, ULR061
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

KCD10_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.067525 (rank : 136)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q922M3	Gene names	Kctd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

KCD11_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.145201 (rank : 99)
Query Neighborhood Hits	173	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	Q693B1	Gene names	KCTD11, REN
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCD11_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.147630 (rank : 98)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K485	Gene names	Kctd11, Ren
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCD13_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.067074 (rank : 137)
Query Neighborhood Hits	173	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZ19, Q96P93, Q96SA1	Gene names	KCTD13, PDIP1, POLDIP1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1) (TNFAIP1-like protein).

KCD13_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.066801 (rank : 138)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BGV7, Q6AXE9	Gene names	Kctd13, Poldip1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1).

KCD18_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.100398 (rank : 131)
Query Neighborhood Hits	173	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

KCNK4_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.079120 (rank : 133)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK6_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.113830 (rank : 118)
Query Neighborhood Hits	173	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK7_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.066420 (rank : 139)
Query Neighborhood Hits	173	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNK7_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.070153 (rank : 134)
Query Neighborhood Hits	173	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK9_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.100656 (rank : 130)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.099418 (rank : 132)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCTD2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.158144 (rank : 88)
Query Neighborhood Hits	173	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CEZ0	Gene names	Kctd2
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

SC10A_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.109154 (rank : 124)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

TNAP1_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.060843 (rank : 141)
Query Neighborhood Hits	173	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	Q13829	Gene names	TNFAIP1, EDP1
Domain Architecture
Description	BTB/POZ domain-containing protein TNFAIP1 (Tumor necrosis factor, alpha-induced protein 1, endothelial) (Protein B12).

Hits sorted by NC score

KCNC3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	173	Target Neighborhood Hits	173	Shared Neighborhood Hits	173
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_HUMAN
NC score	0.995350 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	173	Target Neighborhood Hits	256	Shared Neighborhood Hits	150
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC1_MOUSE
NC score	0.990789 (rank : 3)	θ value	4.84403e-179 (rank : 3)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	117
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_HUMAN
NC score	0.990686 (rank : 4)	θ value	6.32649e-179 (rank : 4)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	117
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC4_HUMAN
NC score	0.989055 (rank : 5)	θ value	2.85304e-163 (rank : 6)
Query Neighborhood Hits	173	Target Neighborhood Hits	141	Shared Neighborhood Hits	114
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
NC score	0.987994 (rank : 6)	θ value	7.508e-164 (rank : 5)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	112
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNF1_HUMAN
NC score	0.942290 (rank : 7)	θ value	4.10295e-61 (rank : 7)
Query Neighborhood Hits	173	Target Neighborhood Hits	109	Shared Neighborhood Hits	92
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNG3_HUMAN
NC score	0.941521 (rank : 8)	θ value	7.75577e-52 (rank : 14)
Query Neighborhood Hits	173	Target Neighborhood Hits	91	Shared Neighborhood Hits	82
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
NC score	0.941188 (rank : 9)	θ value	2.94719e-51 (rank : 17)
Query Neighborhood Hits	173	Target Neighborhood Hits	91	Shared Neighborhood Hits	83
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCND2_HUMAN
NC score	0.939084 (rank : 10)	θ value	4.53632e-60 (rank : 8)
Query Neighborhood Hits	173	Target Neighborhood Hits	154	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
NC score	0.938974 (rank : 11)	θ value	4.53632e-60 (rank : 9)
Query Neighborhood Hits	173	Target Neighborhood Hits	156	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNS3_HUMAN
NC score	0.938166 (rank : 12)	θ value	1.16164e-39 (rank : 32)
Query Neighborhood Hits	173	Target Neighborhood Hits	125	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNS2_HUMAN
NC score	0.937632 (rank : 13)	θ value	1.90589e-58 (rank : 13)
Query Neighborhood Hits	173	Target Neighborhood Hits	129	Shared Neighborhood Hits	110
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
NC score	0.937505 (rank : 14)	θ value	6.55044e-59 (rank : 12)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	110
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNV2_HUMAN
NC score	0.937381 (rank : 15)	θ value	2.95404e-43 (rank : 22)
Query Neighborhood Hits	173	Target Neighborhood Hits	137	Shared Neighborhood Hits	112
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCND3_MOUSE
NC score	0.936838 (rank : 16)	θ value	3.84025e-59 (rank : 11)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.936444 (rank : 17)	θ value	3.84025e-59 (rank : 10)
Query Neighborhood Hits	173	Target Neighborhood Hits	162	Shared Neighborhood Hits	120
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNB1_MOUSE
NC score	0.934733 (rank : 18)	θ value	1.72781e-51 (rank : 16)
Query Neighborhood Hits	173	Target Neighborhood Hits	154	Shared Neighborhood Hits	111
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNB1_HUMAN
NC score	0.934117 (rank : 19)	θ value	1.72781e-51 (rank : 15)
Query Neighborhood Hits	173	Target Neighborhood Hits	169	Shared Neighborhood Hits	111
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNG1_HUMAN
NC score	0.932219 (rank : 20)	θ value	2.11701e-41 (rank : 28)
Query Neighborhood Hits	173	Target Neighborhood Hits	103	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNB2_HUMAN
NC score	0.932190 (rank : 21)	θ value	9.48078e-50 (rank : 19)
Query Neighborhood Hits	173	Target Neighborhood Hits	212	Shared Neighborhood Hits	113
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNS1_HUMAN
NC score	0.932142 (rank : 22)	θ value	3.73686e-38 (rank : 34)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	99
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCND1_HUMAN
NC score	0.931643 (rank : 23)	θ value	4.71619e-41 (rank : 29)
Query Neighborhood Hits	173	Target Neighborhood Hits	160	Shared Neighborhood Hits	119
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
NC score	0.930131 (rank : 24)	θ value	1.79215e-40 (rank : 30)
Query Neighborhood Hits	173	Target Neighborhood Hits	165	Shared Neighborhood Hits	119
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNS1_MOUSE
NC score	0.929968 (rank : 25)	θ value	1.01765e-35 (rank : 37)
Query Neighborhood Hits	173	Target Neighborhood Hits	114	Shared Neighborhood Hits	97
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNA6_HUMAN
NC score	0.925388 (rank : 26)	θ value	1.23823e-49 (rank : 20)
Query Neighborhood Hits	173	Target Neighborhood Hits	100	Shared Neighborhood Hits	87
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA6_MOUSE
NC score	0.925347 (rank : 27)	θ value	8.57503e-51 (rank : 18)
Query Neighborhood Hits	173	Target Neighborhood Hits	106	Shared Neighborhood Hits	90
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG4_HUMAN
NC score	0.923268 (rank : 28)	θ value	1.57365e-28 (rank : 38)
Query Neighborhood Hits	173	Target Neighborhood Hits	99	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNA4_MOUSE
NC score	0.922183 (rank : 29)	θ value	6.58091e-43 (rank : 24)
Query Neighborhood Hits	173	Target Neighborhood Hits	98	Shared Neighborhood Hits	83
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA1_MOUSE
NC score	0.921861 (rank : 30)	θ value	8.59492e-43 (rank : 25)
Query Neighborhood Hits	173	Target Neighborhood Hits	103	Shared Neighborhood Hits	92
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.921851 (rank : 31)	θ value	3.85808e-43 (rank : 23)
Query Neighborhood Hits	173	Target Neighborhood Hits	104	Shared Neighborhood Hits	91
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA4_HUMAN
NC score	0.921788 (rank : 32)	θ value	1.73182e-43 (rank : 21)
Query Neighborhood Hits	173	Target Neighborhood Hits	108	Shared Neighborhood Hits	84
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA3_HUMAN
NC score	0.920673 (rank : 33)	θ value	4.2656e-42 (rank : 27)
Query Neighborhood Hits	173	Target Neighborhood Hits	101	Shared Neighborhood Hits	89
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
NC score	0.920151 (rank : 34)	θ value	1.91475e-42 (rank : 26)
Query Neighborhood Hits	173	Target Neighborhood Hits	103	Shared Neighborhood Hits	88
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA5_HUMAN
NC score	0.918021 (rank : 35)	θ value	8.89434e-40 (rank : 31)
Query Neighborhood Hits	173	Target Neighborhood Hits	124	Shared Neighborhood Hits	88
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
NC score	0.917472 (rank : 36)	θ value	2.86122e-38 (rank : 33)
Query Neighborhood Hits	173	Target Neighborhood Hits	119	Shared Neighborhood Hits	91
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNG2_HUMAN
NC score	0.915275 (rank : 37)	θ value	8.08199e-25 (rank : 39)
Query Neighborhood Hits	173	Target Neighborhood Hits	83	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNA2_MOUSE
NC score	0.915031 (rank : 38)	θ value	4.88048e-38 (rank : 35)
Query Neighborhood Hits	173	Target Neighborhood Hits	102	Shared Neighborhood Hits	89
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA2_HUMAN
NC score	0.914776 (rank : 39)	θ value	8.32485e-38 (rank : 36)
Query Neighborhood Hits	173	Target Neighborhood Hits	101	Shared Neighborhood Hits	88
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNQ1_HUMAN
NC score	0.752179 (rank : 40)	θ value	4.02038e-16 (rank : 40)
Query Neighborhood Hits	173	Target Neighborhood Hits	99	Shared Neighborhood Hits	73
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
NC score	0.744790 (rank : 41)	θ value	5.25075e-16 (rank : 43)
Query Neighborhood Hits	173	Target Neighborhood Hits	175	Shared Neighborhood Hits	79
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ2_HUMAN
NC score	0.725138 (rank : 42)	θ value	4.02038e-16 (rank : 41)
Query Neighborhood Hits	173	Target Neighborhood Hits	114	Shared Neighborhood Hits	75
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.724277 (rank : 43)	θ value	4.02038e-16 (rank : 42)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ5_HUMAN
NC score	0.712925 (rank : 44)	θ value	5.8054e-15 (rank : 44)
Query Neighborhood Hits	173	Target Neighborhood Hits	163	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNQ4_HUMAN
NC score	0.706812 (rank : 45)	θ value	4.16044e-13 (rank : 45)
Query Neighborhood Hits	173	Target Neighborhood Hits	136	Shared Neighborhood Hits	82
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNQ3_MOUSE
NC score	0.685269 (rank : 46)	θ value	5.43371e-13 (rank : 47)
Query Neighborhood Hits	173	Target Neighborhood Hits	105	Shared Neighborhood Hits	74
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_HUMAN
NC score	0.684019 (rank : 47)	θ value	5.43371e-13 (rank : 46)
Query Neighborhood Hits	173	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCMA1_MOUSE
NC score	0.467845 (rank : 48)	θ value	0.000121331 (rank : 50)
Query Neighborhood Hits	173	Target Neighborhood Hits	94	Shared Neighborhood Hits	70
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.466932 (rank : 49)	θ value	0.000121331 (rank : 49)
Query Neighborhood Hits	173	Target Neighborhood Hits	96	Shared Neighborhood Hits	70
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCTD1_HUMAN
NC score	0.339988 (rank : 50)	θ value	0.0148317 (rank : 65)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	Q719H9	Gene names	KCTD1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCTD1_MOUSE
NC score	0.339988 (rank : 51)	θ value	0.0148317 (rank : 66)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	64
SwissProt Accessions	Q5M956, Q5EER9	Gene names	Kctd1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD1.

KCD15_HUMAN
NC score	0.334939 (rank : 52)	θ value	0.00228821 (rank : 58)
Query Neighborhood Hits	173	Target Neighborhood Hits	76	Shared Neighborhood Hits	64
SwissProt Accessions	Q96SI1, Q9BVI6	Gene names	KCTD15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCTD6_MOUSE
NC score	0.333771 (rank : 53)	θ value	0.0148317 (rank : 68)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BNL5, Q3TXX1	Gene names	Kctd6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD6_HUMAN
NC score	0.330346 (rank : 54)	θ value	0.0148317 (rank : 67)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NC69, Q8NBS6, Q8TCA6	Gene names	KCTD6
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD6.

KCTD4_MOUSE
NC score	0.329960 (rank : 55)	θ value	0.00020696 (rank : 52)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D7X1, Q8CCQ3, Q9CYK4	Gene names	Kctd4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCTD4_HUMAN
NC score	0.327935 (rank : 56)	θ value	0.000270298 (rank : 54)
Query Neighborhood Hits	173	Target Neighborhood Hits	72	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WVF5	Gene names	KCTD4
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD4.

KCD15_MOUSE
NC score	0.324683 (rank : 57)	θ value	0.00509761 (rank : 62)
Query Neighborhood Hits	173	Target Neighborhood Hits	78	Shared Neighborhood Hits	63
SwissProt Accessions	Q8K0E1	Gene names	Kctd15
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD15.

KCTD2_HUMAN
NC score	0.318850 (rank : 58)	θ value	0.00665767 (rank : 63)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	53
SwissProt Accessions	Q14681	Gene names	KCTD2, KIAA0176
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCTD3_HUMAN
NC score	0.318386 (rank : 59)	θ value	2.44474e-05 (rank : 48)
Query Neighborhood Hits	173	Target Neighborhood Hits	90	Shared Neighborhood Hits	60
SwissProt Accessions	Q9Y597, Q49AG7, Q504Q9, Q6PJN6, Q8ND58, Q8NDJ0, Q8WX16	Gene names	KCTD3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3 (NY-REN-45 antigen).

KCTD5_MOUSE
NC score	0.313280 (rank : 60)	θ value	0.000461057 (rank : 55)
Query Neighborhood Hits	173	Target Neighborhood Hits	64	Shared Neighborhood Hits	53
SwissProt Accessions	Q8VC57	Gene names	Kctd5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCTD5_HUMAN
NC score	0.309611 (rank : 61)	θ value	0.00228821 (rank : 59)
Query Neighborhood Hits	173	Target Neighborhood Hits	66	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NXV2	Gene names	KCTD5
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD5.

KCNN4_MOUSE
NC score	0.302192 (rank : 62)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	66
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNN4_HUMAN
NC score	0.300013 (rank : 63)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	173	Target Neighborhood Hits	90	Shared Neighborhood Hits	66
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCTD3_MOUSE
NC score	0.299986 (rank : 64)	θ value	0.00102713 (rank : 56)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BFX3, Q6P7X4	Gene names	Kctd3
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD3.

KCNRG_HUMAN
NC score	0.296145 (rank : 65)	θ value	0.0563607 (rank : 73)
Query Neighborhood Hits	173	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	Q8N5I3, Q8IU75, Q8N3Q9	Gene names	KCNRG, CLLD4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCNRG_MOUSE
NC score	0.293517 (rank : 66)	θ value	0.00175202 (rank : 57)
Query Neighborhood Hits	173	Target Neighborhood Hits	68	Shared Neighborhood Hits	57
SwissProt Accessions	Q2TUM3, Q6P8J6, Q8C6V1	Gene names	Kcnrg, Clld4
Domain Architecture	No domain graphic available
Description	Putative potassium channel regulatory protein (Potassium channel regulator) (Protein CLLD4).

KCTD7_MOUSE
NC score	0.281901 (rank : 67)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BJK1, Q3USA6, Q8C0S7	Gene names	Kctd7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCD14_HUMAN
NC score	0.269593 (rank : 68)	θ value	0.00020696 (rank : 51)
Query Neighborhood Hits	173	Target Neighborhood Hits	59	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BQ13	Gene names	KCTD14
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD14.

KCTD7_HUMAN
NC score	0.261886 (rank : 69)	θ value	0.47712 (rank : 102)
Query Neighborhood Hits	173	Target Neighborhood Hits	74	Shared Neighborhood Hits	55
SwissProt Accessions	Q96MP8, Q8IVR0	Gene names	KCTD7
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD7.

KCNN2_HUMAN
NC score	0.258265 (rank : 70)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	173	Target Neighborhood Hits	117	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.258264 (rank : 71)	θ value	0.21417 (rank : 89)
Query Neighborhood Hits	173	Target Neighborhood Hits	120	Shared Neighborhood Hits	65
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN3_HUMAN
NC score	0.252754 (rank : 72)	θ value	0.21417 (rank : 90)
Query Neighborhood Hits	173	Target Neighborhood Hits	216	Shared Neighborhood Hits	65
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCD17_HUMAN
NC score	0.252601 (rank : 73)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	173	Target Neighborhood Hits	85	Shared Neighborhood Hits	50
SwissProt Accessions	Q8N5Z5, O95517	Gene names	KCTD17
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD17.

KCNN3_MOUSE
NC score	0.251195 (rank : 74)	θ value	0.21417 (rank : 91)
Query Neighborhood Hits	173	Target Neighborhood Hits	171	Shared Neighborhood Hits	69
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCNN1_MOUSE
NC score	0.248264 (rank : 75)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	173	Target Neighborhood Hits	117	Shared Neighborhood Hits	67
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_HUMAN
NC score	0.247046 (rank : 76)	θ value	0.279714 (rank : 94)
Query Neighborhood Hits	173	Target Neighborhood Hits	125	Shared Neighborhood Hits	65
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNT1_HUMAN
NC score	0.243055 (rank : 77)	θ value	0.00869519 (rank : 64)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	60
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCTD9_MOUSE
NC score	0.233207 (rank : 78)	θ value	0.0736092 (rank : 77)
Query Neighborhood Hits	173	Target Neighborhood Hits	63	Shared Neighborhood Hits	51
SwissProt Accessions	Q80UN1	Gene names	Kctd9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCTD9_HUMAN
NC score	0.227045 (rank : 79)	θ value	0.21417 (rank : 92)
Query Neighborhood Hits	173	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q7L273, Q6NUM8, Q9NXV4	Gene names	KCTD9
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD9.

KCNKA_HUMAN
NC score	0.206518 (rank : 80)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	173	Target Neighborhood Hits	111	Shared Neighborhood Hits	67
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCTD8_MOUSE
NC score	0.190954 (rank : 81)	θ value	0.00020696 (rank : 53)
Query Neighborhood Hits	173	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	Q50H33, Q8BR74, Q8C4C2, Q8C906, Q8C9B0, Q8CAA9	Gene names	Kctd8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCTD8_HUMAN
NC score	0.179665 (rank : 82)	θ value	0.00228821 (rank : 60)
Query Neighborhood Hits	173	Target Neighborhood Hits	91	Shared Neighborhood Hits	42
SwissProt Accessions	Q6ZWB6	Gene names	KCTD8
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD8.

KCNKH_HUMAN
NC score	0.175936 (rank : 83)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	173	Target Neighborhood Hits	89	Shared Neighborhood Hits	62
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

SC11A_HUMAN
NC score	0.170685 (rank : 84)	θ value	0.00228821 (rank : 61)
Query Neighborhood Hits	173	Target Neighborhood Hits	111	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

KCNKF_HUMAN
NC score	0.165716 (rank : 85)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	173	Target Neighborhood Hits	87	Shared Neighborhood Hits	61
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCD16_MOUSE
NC score	0.163836 (rank : 86)	θ value	0.163984 (rank : 81)
Query Neighborhood Hits	173	Target Neighborhood Hits	58	Shared Neighborhood Hits	42
SwissProt Accessions	Q5DTY9, Q78Y50	Gene names	Kctd16, Kiaa1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCD16_HUMAN
NC score	0.159063 (rank : 87)	θ value	0.21417 (rank : 86)
Query Neighborhood Hits	173	Target Neighborhood Hits	60	Shared Neighborhood Hits	41
SwissProt Accessions	Q68DU8, Q9P2M9	Gene names	KCTD16, KIAA1317
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD16.

KCTD2_MOUSE
NC score	0.158144 (rank : 88)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	173	Target Neighborhood Hits	55	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CEZ0	Gene names	Kctd2
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD2.

KCNT1_MOUSE
NC score	0.157987 (rank : 89)	θ value	0.0736092 (rank : 76)
Query Neighborhood Hits	173	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

CAC1H_MOUSE
NC score	0.155417 (rank : 90)	θ value	0.0961366 (rank : 78)
Query Neighborhood Hits	173	Target Neighborhood Hits	230	Shared Neighborhood Hits	63
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

KCD12_HUMAN
NC score	0.154861 (rank : 91)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	173	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q96CX2	Gene names	KCTD12, C13orf2, KIAA1778, PFET1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

SC11A_MOUSE
NC score	0.153071 (rank : 92)	θ value	0.0563607 (rank : 75)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	60
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

CAC1I_HUMAN
NC score	0.152126 (rank : 93)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	173	Target Neighborhood Hits	138	Shared Neighborhood Hits	62
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1H_HUMAN
NC score	0.151518 (rank : 94)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	173	Target Neighborhood Hits	307	Shared Neighborhood Hits	59
SwissProt Accessions	O95180, O95802, Q8WWI6, Q96QI6, Q96RZ9, Q9NYY4, Q9NYY5	Gene names	CACNA1H
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2) (Low-voltage-activated calcium channel alpha1 3.2 subunit).

SCN4A_HUMAN
NC score	0.150766 (rank : 95)	θ value	0.279714 (rank : 98)
Query Neighborhood Hits	173	Target Neighborhood Hits	133	Shared Neighborhood Hits	65
SwissProt Accessions	P35499, Q15478, Q16447, Q7Z6B1	Gene names	SCN4A
Domain Architecture
Description	Sodium channel protein type 4 subunit alpha (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4) (Sodium channel protein, skeletal muscle subunit alpha) (SkM1).

KCNKG_HUMAN
NC score	0.149624 (rank : 96)	θ value	5.27518 (rank : 153)
Query Neighborhood Hits	173	Target Neighborhood Hits	90	Shared Neighborhood Hits	65
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCD12_MOUSE
NC score	0.148792 (rank : 97)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	173	Target Neighborhood Hits	66	Shared Neighborhood Hits	41
SwissProt Accessions	Q6WVG3	Gene names	Kctd12, Pfet1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain).

KCD11_MOUSE
NC score	0.147630 (rank : 98)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	173	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K485	Gene names	Kctd11, Ren
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCD11_HUMAN
NC score	0.145201 (rank : 99)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	173	Target Neighborhood Hits	50	Shared Neighborhood Hits	40
SwissProt Accessions	Q693B1	Gene names	KCTD11, REN
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD11.

KCNK3_MOUSE
NC score	0.143376 (rank : 100)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	173	Target Neighborhood Hits	93	Shared Neighborhood Hits	65
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK3_HUMAN
NC score	0.142870 (rank : 101)	θ value	3.0926 (rank : 140)
Query Neighborhood Hits	173	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK2_MOUSE
NC score	0.135021 (rank : 102)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	173	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK5_HUMAN
NC score	0.134729 (rank : 103)	θ value	5.27518 (rank : 152)
Query Neighborhood Hits	173	Target Neighborhood Hits	102	Shared Neighborhood Hits	65
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNK2_HUMAN
NC score	0.130772 (rank : 104)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

CAC1F_MOUSE
NC score	0.129875 (rank : 105)	θ value	0.0193708 (rank : 69)
Query Neighborhood Hits	173	Target Neighborhood Hits	142	Shared Neighborhood Hits	52
SwissProt Accessions	Q9JIS7	Gene names	Cacna1f
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

CAC1F_HUMAN
NC score	0.128960 (rank : 106)	θ value	0.0330416 (rank : 70)
Query Neighborhood Hits	173	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	O60840, O43901	Gene names	CACNA1F, CACNAF1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage- gated calcium channel subunit alpha Cav1.4).

SC10A_MOUSE
NC score	0.124903 (rank : 107)	θ value	0.0563607 (rank : 74)
Query Neighborhood Hits	173	Target Neighborhood Hits	107	Shared Neighborhood Hits	52
SwissProt Accessions	Q6QIY3, Q62243, Q6EWG7, Q6KCH7, Q703F9	Gene names	Scn10a, Pn3, Sns
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (Sensory neuron sodium channel).

CAC1A_HUMAN
NC score	0.124845 (rank : 108)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	173	Target Neighborhood Hits	387	Shared Neighborhood Hits	65
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1B_MOUSE
NC score	0.124078 (rank : 109)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	173	Target Neighborhood Hits	351	Shared Neighborhood Hits	62
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CAC1A_MOUSE
NC score	0.123641 (rank : 110)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	173	Target Neighborhood Hits	267	Shared Neighborhood Hits	62
SwissProt Accessions	P97445	Gene names	Cacna1a, Cach4, Cacn3, Cacnl1a4, Ccha1a
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CAC1D_HUMAN
NC score	0.121572 (rank : 111)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	53
SwissProt Accessions	Q01668, Q13916, Q13931	Gene names	CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1D (Voltage- gated calcium channel subunit alpha Cav1.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 2).

CAC1G_HUMAN
NC score	0.119982 (rank : 112)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	173	Target Neighborhood Hits	587	Shared Neighborhood Hits	62
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

SCN5A_HUMAN
NC score	0.119350 (rank : 113)	θ value	0.279714 (rank : 99)
Query Neighborhood Hits	173	Target Neighborhood Hits	145	Shared Neighborhood Hits	49
SwissProt Accessions	Q14524	Gene names	SCN5A
Domain Architecture
Description	Sodium channel protein type 5 subunit alpha (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (Sodium channel protein, cardiac muscle alpha-subunit) (HH1).

SCN9A_HUMAN
NC score	0.116003 (rank : 114)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	50
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN8A_HUMAN
NC score	0.115535 (rank : 115)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
NC score	0.114527 (rank : 116)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	173	Target Neighborhood Hits	136	Shared Neighborhood Hits	52
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

CAC1B_HUMAN
NC score	0.114240 (rank : 117)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	173	Target Neighborhood Hits	257	Shared Neighborhood Hits	55
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

KCNK6_HUMAN
NC score	0.113830 (rank : 118)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	173	Target Neighborhood Hits	79	Shared Neighborhood Hits	52
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

SCN3A_HUMAN
NC score	0.113564 (rank : 119)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	173	Target Neighborhood Hits	115	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

CAC1S_MOUSE
NC score	0.113366 (rank : 120)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	173	Target Neighborhood Hits	98	Shared Neighborhood Hits	52
SwissProt Accessions	Q02789, Q99240	Gene names	Cacna1s, Cach1, Cach1b, Cacn1, Cacnl1a3
Domain Architecture	No domain graphic available
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1S_HUMAN
NC score	0.112727 (rank : 121)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	173	Target Neighborhood Hits	92	Shared Neighborhood Hits	49
SwissProt Accessions	Q13698, Q12896, Q13934	Gene names	CACNA1S, CACH1, CACN1, CACNL1A3
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1S (Voltage- gated calcium channel subunit alpha Cav1.1) (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle).

CAC1C_MOUSE
NC score	0.110432 (rank : 122)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	173	Target Neighborhood Hits	130	Shared Neighborhood Hits	47
SwissProt Accessions	Q01815, Q04476, Q61242, Q99242	Gene names	Cacna1c, Cach2, Cacn2, Cacnl1a1, Cchl1a1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Mouse brain class C) (MBC) (MELC-CC).

CAC1E_MOUSE
NC score	0.109356 (rank : 123)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	173	Target Neighborhood Hits	167	Shared Neighborhood Hits	50
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SC10A_HUMAN
NC score	0.109154 (rank : 124)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	173	Target Neighborhood Hits	116	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y5Y9	Gene names	SCN10A, PN3
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 10 subunit alpha (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8) (Peripheral nerve sodium channel 3) (hPN3).

CAC1E_HUMAN
NC score	0.108877 (rank : 125)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	173	Target Neighborhood Hits	148	Shared Neighborhood Hits	49
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

SCN1A_HUMAN
NC score	0.107204 (rank : 126)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	173	Target Neighborhood Hits	148	Shared Neighborhood Hits	46
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

CAC1C_HUMAN
NC score	0.106282 (rank : 127)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	173	Target Neighborhood Hits	158	Shared Neighborhood Hits	51
SwissProt Accessions	Q13936, Q13917, Q13918, Q13919, Q13920, Q13921, Q13922, Q13923, Q13924, Q13925, Q13926, Q13927, Q13928, Q13929, Q13930, Q13932, Q13933, Q14743, Q14744, Q15877, Q99025, Q99241, Q99875	Gene names	CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
Domain Architecture
Description	Voltage-dependent L-type calcium channel subunit alpha-1C (Voltage- gated calcium channel subunit alpha Cav1.2) (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle).

SCN2A_HUMAN
NC score	0.102375 (rank : 128)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	173	Target Neighborhood Hits	157	Shared Neighborhood Hits	46
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN7A_HUMAN
NC score	0.102305 (rank : 129)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	173	Target Neighborhood Hits	135	Shared Neighborhood Hits	56
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

KCNK9_HUMAN
NC score	0.100656 (rank : 130)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCD18_HUMAN
NC score	0.100398 (rank : 131)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	173	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

KCNK9_MOUSE
NC score	0.099418 (rank : 132)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	173	Target Neighborhood Hits	86	Shared Neighborhood Hits	58
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK4_MOUSE
NC score	0.079120 (rank : 133)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	173	Target Neighborhood Hits	118	Shared Neighborhood Hits	49
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK7_MOUSE
NC score	0.070153 (rank : 134)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	173	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK4_HUMAN
NC score	0.067641 (rank : 135)	θ value	5.27518 (rank : 151)
Query Neighborhood Hits	173	Target Neighborhood Hits	109	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCD10_MOUSE
NC score	0.067525 (rank : 136)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q922M3	Gene names	Kctd10
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

KCD13_HUMAN
NC score	0.067074 (rank : 137)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	173	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WZ19, Q96P93, Q96SA1	Gene names	KCTD13, PDIP1, POLDIP1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1) (TNFAIP1-like protein).

KCD13_MOUSE
NC score	0.066801 (rank : 138)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	173	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BGV7, Q6AXE9	Gene names	Kctd13, Poldip1
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD13 (Polymerase delta-interacting protein 1).

KCNK7_HUMAN
NC score	0.066420 (rank : 139)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	173	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCD10_HUMAN
NC score	0.064429 (rank : 140)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	173	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H3F6, Q53HN2, Q59FV1, Q6PL47, Q96SU0	Gene names	KCTD10, ULR061
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD10.

TNAP1_HUMAN
NC score	0.060843 (rank : 141)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	173	Target Neighborhood Hits	44	Shared Neighborhood Hits	27
SwissProt Accessions	Q13829	Gene names	TNFAIP1, EDP1
Domain Architecture
Description	BTB/POZ domain-containing protein TNFAIP1 (Tumor necrosis factor, alpha-induced protein 1, endothelial) (Protein B12).

MTSS1_HUMAN
NC score	0.037626 (rank : 142)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	173	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MTSS1_MOUSE
NC score	0.037019 (rank : 143)	θ value	0.0961366 (rank : 79)
Query Neighborhood Hits	173	Target Neighborhood Hits	592	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

BAT2_HUMAN
NC score	0.024659 (rank : 144)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	173	Target Neighborhood Hits	931	Shared Neighborhood Hits	44
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

EP300_HUMAN
NC score	0.024155 (rank : 145)	θ value	0.0431538 (rank : 71)
Query Neighborhood Hits	173	Target Neighborhood Hits	821	Shared Neighborhood Hits	35
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

BAT2_MOUSE
NC score	0.023918 (rank : 146)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	173	Target Neighborhood Hits	947	Shared Neighborhood Hits	36
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CEBPE_HUMAN
NC score	0.023055 (rank : 147)	θ value	0.21417 (rank : 85)
Query Neighborhood Hits	173	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CF155_HUMAN
NC score	0.021889 (rank : 148)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	173	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H8W2, Q5TG13	Gene names	C6orf155
Domain Architecture	No domain graphic available
Description	Protein C6orf155.

PSL1_HUMAN
NC score	0.019833 (rank : 149)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	173	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

ATX7_MOUSE
NC score	0.019759 (rank : 150)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	173	Target Neighborhood Hits	328	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CIC_HUMAN
NC score	0.018112 (rank : 151)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	173	Target Neighborhood Hits	992	Shared Neighborhood Hits	34
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

E2F4_HUMAN
NC score	0.016646 (rank : 152)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	173	Target Neighborhood Hits	188	Shared Neighborhood Hits	6
SwissProt Accessions	Q16254, Q12991, Q15328	Gene names	E2F4
Domain Architecture
Description	Transcription factor E2F4 (E2F-4).

CD2_HUMAN
NC score	0.016350 (rank : 153)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	173	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	P06729, Q96TE5	Gene names	CD2
Domain Architecture
Description	T-cell surface antigen CD2 precursor (T-cell surface antigen T11/Leu- 5) (LFA-2) (LFA-3 receptor) (Erythrocyte receptor) (Rosette receptor).

RECQ5_HUMAN
NC score	0.016104 (rank : 154)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	173	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

DIDO1_HUMAN
NC score	0.014596 (rank : 155)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	173	Target Neighborhood Hits	960	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GR65_HUMAN
NC score	0.014528 (rank : 156)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	173	Target Neighborhood Hits	148	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BQQ3, Q8N272, Q96H42	Gene names	GORASP1, GRASP65
Domain Architecture	No domain graphic available
Description	Golgi reassembly-stacking protein 1 (Golgi reassembly-stacking protein of 65 kDa) (GRASP65) (Golgi peripheral membrane protein p65) (Golgi phosphoprotein 5) (GOLPH5).

MELPH_HUMAN
NC score	0.012925 (rank : 157)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	173	Target Neighborhood Hits	145	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

CD248_HUMAN
NC score	0.012213 (rank : 158)	θ value	0.21417 (rank : 84)
Query Neighborhood Hits	173	Target Neighborhood Hits	679	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

IRK13_HUMAN
NC score	0.011655 (rank : 159)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	173	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

SPR1A_HUMAN
NC score	0.011409 (rank : 160)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	173	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	P35321, Q9UDG4	Gene names	SPRR1A
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein IA) (SPR-IA) (SPRK) (19 kDa pancornulin).

K2027_HUMAN
NC score	0.010050 (rank : 161)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	173	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

IRF3_HUMAN
NC score	0.009801 (rank : 162)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	173	Target Neighborhood Hits	129	Shared Neighborhood Hits	7
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

SPR1A_MOUSE
NC score	0.009652 (rank : 163)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	173	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

TARSH_HUMAN
NC score	0.009627 (rank : 164)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	173	Target Neighborhood Hits	768	Shared Neighborhood Hits	24
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

IF4B_MOUSE
NC score	0.009340 (rank : 165)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	173	Target Neighborhood Hits	368	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

BCL9_HUMAN
NC score	0.008820 (rank : 166)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	173	Target Neighborhood Hits	1008	Shared Neighborhood Hits	29
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

RGS3_HUMAN
NC score	0.008285 (rank : 167)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	173	Target Neighborhood Hits	1375	Shared Neighborhood Hits	26
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

DCP1A_HUMAN
NC score	0.007863 (rank : 168)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	173	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

CEL_HUMAN
NC score	0.007637 (rank : 169)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	173	Target Neighborhood Hits	896	Shared Neighborhood Hits	25
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NCOR2_MOUSE
NC score	0.007525 (rank : 170)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	173	Target Neighborhood Hits	790	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

SPR1B_MOUSE
NC score	0.007457 (rank : 171)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	173	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

COIA1_HUMAN
NC score	0.006757 (rank : 172)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	173	Target Neighborhood Hits	447	Shared Neighborhood Hits	24
SwissProt Accessions	P39060, Q9UK38, Q9Y6Q7, Q9Y6Q8	Gene names	COL18A1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

BAZ2A_HUMAN
NC score	0.006704 (rank : 173)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	173	Target Neighborhood Hits	780	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

SC24A_MOUSE
NC score	0.006099 (rank : 174)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	173	Target Neighborhood Hits	394	Shared Neighborhood Hits	18
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SCAP_HUMAN
NC score	0.005445 (rank : 175)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	173	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

SON_HUMAN
NC score	0.005381 (rank : 176)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	173	Target Neighborhood Hits	1568	Shared Neighborhood Hits	31
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TBCD1_HUMAN
NC score	0.005105 (rank : 177)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	173	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

PLCB2_HUMAN
NC score	0.004010 (rank : 178)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	173	Target Neighborhood Hits	608	Shared Neighborhood Hits	9
SwissProt Accessions	Q00722	Gene names	PLCB2
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-2) (PLC-beta-2).

TXLNB_HUMAN
NC score	0.003483 (rank : 179)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	173	Target Neighborhood Hits	912	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

TXD11_HUMAN
NC score	0.002741 (rank : 180)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	173	Target Neighborhood Hits	402	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

CRIM1_HUMAN
NC score	0.002326 (rank : 181)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	173	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

LPP_HUMAN
NC score	0.002229 (rank : 182)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	173	Target Neighborhood Hits	775	Shared Neighborhood Hits	18
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PTPRN_MOUSE
NC score	0.000541 (rank : 183)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	173	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PRGR_MOUSE
NC score	0.000120 (rank : 184)	θ value	5.27518 (rank : 154)
Query Neighborhood Hits	173	Target Neighborhood Hits	286	Shared Neighborhood Hits	7
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

HXB3_HUMAN
NC score	-0.000083 (rank : 185)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	173	Target Neighborhood Hits	559	Shared Neighborhood Hits	12
SwissProt Accessions	P14651, O95615, P17484	Gene names	HOXB3, HOX2G
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2G) (Hox-2.7).

DLG5_HUMAN
NC score	-0.000285 (rank : 186)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	173	Target Neighborhood Hits	1088	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

HXB3_MOUSE
NC score	-0.000323 (rank : 187)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	173	Target Neighborhood Hits	493	Shared Neighborhood Hits	8
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

CSKI2_MOUSE
NC score	-0.001393 (rank : 188)	θ value	5.27518 (rank : 150)
Query Neighborhood Hits	173	Target Neighborhood Hits	812	Shared Neighborhood Hits	19
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TRIM7_HUMAN
NC score	-0.001904 (rank : 189)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	173	Target Neighborhood Hits	336	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

SPEG_MOUSE
NC score	-0.003242 (rank : 190)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	173	Target Neighborhood Hits	1959	Shared Neighborhood Hits	36
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

WNK2_HUMAN
NC score	-0.003725 (rank : 191)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	173	Target Neighborhood Hits	1407	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

RIMB1_MOUSE
NC score	-0.004357 (rank : 192)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	173	Target Neighborhood Hits	1376	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PRDM1_HUMAN
NC score	-0.004585 (rank : 193)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	173	Target Neighborhood Hits	734	Shared Neighborhood Hits	5
SwissProt Accessions	O75626	Gene names	PRDM1, BLIMP1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1) (Positive regulatory domain I-binding factor 1) (PRDI- binding factor 1) (PRDI-BF1).

SIP1_MOUSE
NC score	-0.005383 (rank : 194)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	173	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).