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Network neighborhood for query Sequence : IRK13_HUMAN

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IRK13_HUMAN
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRK13_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

IRK10_HUMAN
θ value	5.7252e-63 (rank : 2)	NC score	0.986411 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P78508, Q8N4I7, Q92808	Gene names	KCNJ10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassium channel Kir4.1).

IRK10_MOUSE
θ value	2.84138e-62 (rank : 3)	NC score	0.986372 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JM63	Gene names	Kcnj10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1).

IRK15_HUMAN
θ value	3.25095e-58 (rank : 4)	NC score	0.985766 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q99712, O00564, Q96L28, Q99446	Gene names	KCNJ15, KCNJ14
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2) (Kir1.3).

IRK15_MOUSE
θ value	5.54529e-58 (rank : 5)	NC score	0.985760 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	O88932, Q9JK34	Gene names	Kcnj15
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2).

IRK1_MOUSE
θ value	5.93839e-52 (rank : 6)	NC score	0.982895 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	O88335	Gene names	Kcnj1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK1_HUMAN
θ value	2.25659e-51 (rank : 7)	NC score	0.982612 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48048, Q6LD67	Gene names	KCNJ1, ROMK1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK2_HUMAN
θ value	1.91031e-50 (rank : 8)	NC score	0.973406 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P63252, O15110, P48049	Gene names	KCNJ2, HIRK1
Domain Architecture	No domain graphic available
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (Cardiac inward rectifier potassium channel) (IRK1).

IRK2_MOUSE
θ value	7.25919e-50 (rank : 9)	NC score	0.973049 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	P35561	Gene names	Kcnj2, Irk1
Domain Architecture
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1).

IRK9_MOUSE
θ value	3.37202e-47 (rank : 10)	NC score	0.974848 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P48543, Q9WUE1	Gene names	Kcnj9, Girk3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK9_HUMAN
θ value	1.28137e-46 (rank : 11)	NC score	0.974666 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q92806, Q5JW75	Gene names	KCNJ9, GIRK3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK14_HUMAN
θ value	3.72821e-46 (rank : 12)	NC score	0.974096 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK14_MOUSE
θ value	3.72821e-46 (rank : 13)	NC score	0.974081 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q8JZN3, Q8BMK3, Q8BXM0	Gene names	Kcnj14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK6_HUMAN
θ value	4.86918e-46 (rank : 14)	NC score	0.972903 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

IRK5_HUMAN
θ value	6.35935e-46 (rank : 15)	NC score	0.973170 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P48544, Q6DK13, Q6DK14, Q92807	Gene names	KCNJ5, GIRK4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK3_HUMAN
θ value	9.18288e-45 (rank : 16)	NC score	0.973032 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK3_MOUSE
θ value	1.19932e-44 (rank : 17)	NC score	0.973026 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P63250, P35562	Gene names	Kcnj3, Girk1
Domain Architecture	No domain graphic available
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK5_MOUSE
θ value	1.56636e-44 (rank : 18)	NC score	0.972881 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48545, P97508	Gene names	Kcnj5, Girk4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK12_HUMAN
θ value	1.01529e-43 (rank : 19)	NC score	0.971521 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14500, O43401, Q8NG63	Gene names	KCNJ12, IRK2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK12_MOUSE
θ value	1.01529e-43 (rank : 20)	NC score	0.971459 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P52187, Q9QYF2	Gene names	Kcnj12, Irk2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK4_HUMAN
θ value	1.62093e-41 (rank : 21)	NC score	0.972611 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

IRK4_MOUSE
θ value	2.76489e-41 (rank : 22)	NC score	0.972524 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P52189	Gene names	Kcnj4, Irk3
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK3).

IRK6_MOUSE
θ value	2.76489e-41 (rank : 23)	NC score	0.971152 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P48542, O70290, P70216, P70306, P70307, P70308, P70309, P70454, Q9QYH5	Gene names	Kcnj6, Girk2, Kcnj7, W
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2).

IRKI_HUMAN
θ value	3.05695e-40 (rank : 24)	NC score	0.970495 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	Q15756	Gene names	KCNJN1
Domain Architecture
Description	Inward rectifying K(+) channel negative regulator Kir2.2v.

IRK16_MOUSE
θ value	5.76516e-39 (rank : 25)	NC score	0.970768 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z307	Gene names	Kcnj16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK11_MOUSE
θ value	4.88048e-38 (rank : 26)	NC score	0.970171 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q61743, Q9QX21	Gene names	Kcnj11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2).

IRK16_HUMAN
θ value	4.88048e-38 (rank : 27)	NC score	0.970435 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPI9	Gene names	KCNJ16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK11_HUMAN
θ value	6.37413e-38 (rank : 28)	NC score	0.969954 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14654, Q58EX3	Gene names	KCNJ11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2) (IKATP).

IRK8_HUMAN
θ value	2.26708e-35 (rank : 29)	NC score	0.967327 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	Q15842, O00657	Gene names	KCNJ8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

IRK8_MOUSE
θ value	3.27365e-34 (rank : 30)	NC score	0.966796 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	32
SwissProt Accessions	P97794	Gene names	Kcnj8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

KCNH8_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.014596 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH4_HUMAN
θ value	0.813845 (rank : 32)	NC score	0.016836 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNG1_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.011608 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNC3_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.011489 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	256	Shared Neighborhood Hits	8
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.011655 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCND1_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.014095 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	160	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND1_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.015061 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	165	Shared Neighborhood Hits	13
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNN2_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.009523 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.009493 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

Hits sorted by NC score

IRK13_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

IRK10_HUMAN
NC score	0.986411 (rank : 2)	θ value	5.7252e-63 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	P78508, Q8N4I7, Q92808	Gene names	KCNJ10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassium channel Kir4.1).

IRK10_MOUSE
NC score	0.986372 (rank : 3)	θ value	2.84138e-62 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	40	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JM63	Gene names	Kcnj10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1).

IRK15_HUMAN
NC score	0.985766 (rank : 4)	θ value	3.25095e-58 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q99712, O00564, Q96L28, Q99446	Gene names	KCNJ15, KCNJ14
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2) (Kir1.3).

IRK15_MOUSE
NC score	0.985760 (rank : 5)	θ value	5.54529e-58 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	O88932, Q9JK34	Gene names	Kcnj15
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2).

IRK1_MOUSE
NC score	0.982895 (rank : 6)	θ value	5.93839e-52 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	O88335	Gene names	Kcnj1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK1_HUMAN
NC score	0.982612 (rank : 7)	θ value	2.25659e-51 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48048, Q6LD67	Gene names	KCNJ1, ROMK1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK9_MOUSE
NC score	0.974848 (rank : 8)	θ value	3.37202e-47 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	P48543, Q9WUE1	Gene names	Kcnj9, Girk3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK9_HUMAN
NC score	0.974666 (rank : 9)	θ value	1.28137e-46 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	32	Shared Neighborhood Hits	31
SwissProt Accessions	Q92806, Q5JW75	Gene names	KCNJ9, GIRK3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK14_HUMAN
NC score	0.974096 (rank : 10)	θ value	3.72821e-46 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK14_MOUSE
NC score	0.974081 (rank : 11)	θ value	3.72821e-46 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q8JZN3, Q8BMK3, Q8BXM0	Gene names	Kcnj14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK2_HUMAN
NC score	0.973406 (rank : 12)	θ value	1.91031e-50 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	P63252, O15110, P48049	Gene names	KCNJ2, HIRK1
Domain Architecture	No domain graphic available
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (Cardiac inward rectifier potassium channel) (IRK1).

IRK5_HUMAN
NC score	0.973170 (rank : 13)	θ value	6.35935e-46 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P48544, Q6DK13, Q6DK14, Q92807	Gene names	KCNJ5, GIRK4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK2_MOUSE
NC score	0.973049 (rank : 14)	θ value	7.25919e-50 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	P35561	Gene names	Kcnj2, Irk1
Domain Architecture
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1).

IRK3_HUMAN
NC score	0.973032 (rank : 15)	θ value	9.18288e-45 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK3_MOUSE
NC score	0.973026 (rank : 16)	θ value	1.19932e-44 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P63250, P35562	Gene names	Kcnj3, Girk1
Domain Architecture	No domain graphic available
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK6_HUMAN
NC score	0.972903 (rank : 17)	θ value	4.86918e-46 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

IRK5_MOUSE
NC score	0.972881 (rank : 18)	θ value	1.56636e-44 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48545, P97508	Gene names	Kcnj5, Girk4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK4_HUMAN
NC score	0.972611 (rank : 19)	θ value	1.62093e-41 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

IRK4_MOUSE
NC score	0.972524 (rank : 20)	θ value	2.76489e-41 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P52189	Gene names	Kcnj4, Irk3
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK3).

IRK12_HUMAN
NC score	0.971521 (rank : 21)	θ value	1.01529e-43 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14500, O43401, Q8NG63	Gene names	KCNJ12, IRK2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK12_MOUSE
NC score	0.971459 (rank : 22)	θ value	1.01529e-43 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P52187, Q9QYF2	Gene names	Kcnj12, Irk2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK6_MOUSE
NC score	0.971152 (rank : 23)	θ value	2.76489e-41 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P48542, O70290, P70216, P70306, P70307, P70308, P70309, P70454, Q9QYH5	Gene names	Kcnj6, Girk2, Kcnj7, W
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2).

IRK16_MOUSE
NC score	0.970768 (rank : 24)	θ value	5.76516e-39 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z307	Gene names	Kcnj16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRKI_HUMAN
NC score	0.970495 (rank : 25)	θ value	3.05695e-40 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	Q15756	Gene names	KCNJN1
Domain Architecture
Description	Inward rectifying K(+) channel negative regulator Kir2.2v.

IRK16_HUMAN
NC score	0.970435 (rank : 26)	θ value	4.88048e-38 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPI9	Gene names	KCNJ16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK11_MOUSE
NC score	0.970171 (rank : 27)	θ value	4.88048e-38 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q61743, Q9QX21	Gene names	Kcnj11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2).

IRK11_HUMAN
NC score	0.969954 (rank : 28)	θ value	6.37413e-38 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14654, Q58EX3	Gene names	KCNJ11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2) (IKATP).

IRK8_HUMAN
NC score	0.967327 (rank : 29)	θ value	2.26708e-35 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	Q15842, O00657	Gene names	KCNJ8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

IRK8_MOUSE
NC score	0.966796 (rank : 30)	θ value	3.27365e-34 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	34	Shared Neighborhood Hits	32
SwissProt Accessions	P97794	Gene names	Kcnj8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

KCNH4_HUMAN
NC score	0.016836 (rank : 31)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCND1_MOUSE
NC score	0.015061 (rank : 32)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	165	Shared Neighborhood Hits	13
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNH8_HUMAN
NC score	0.014596 (rank : 33)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCND1_HUMAN
NC score	0.014095 (rank : 34)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	160	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNC3_MOUSE
NC score	0.011655 (rank : 35)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	173	Shared Neighborhood Hits	8
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNG1_HUMAN
NC score	0.011608 (rank : 36)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNC3_HUMAN
NC score	0.011489 (rank : 37)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	256	Shared Neighborhood Hits	8
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNN2_HUMAN
NC score	0.009523 (rank : 38)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
NC score	0.009493 (rank : 39)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).