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Network neighborhood for query Sequence : IRK14_HUMAN

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IRK14_HUMAN
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IRK14_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK14_MOUSE
θ value	0 (rank : 2)	NC score	0.999876 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q8JZN3, Q8BMK3, Q8BXM0	Gene names	Kcnj14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK2_HUMAN
θ value	9.54178e-143 (rank : 3)	NC score	0.996794 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	P63252, O15110, P48049	Gene names	KCNJ2, HIRK1
Domain Architecture	No domain graphic available
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (Cardiac inward rectifier potassium channel) (IRK1).

IRK2_MOUSE
θ value	2.77624e-142 (rank : 4)	NC score	0.996441 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	P35561	Gene names	Kcnj2, Irk1
Domain Architecture
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1).

IRK12_HUMAN
θ value	1.20984e-129 (rank : 5)	NC score	0.996399 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14500, O43401, Q8NG63	Gene names	KCNJ12, IRK2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK12_MOUSE
θ value	7.84197e-129 (rank : 6)	NC score	0.996232 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P52187, Q9QYF2	Gene names	Kcnj12, Irk2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK4_HUMAN
θ value	1.02419e-128 (rank : 7)	NC score	0.997165 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

IRK4_MOUSE
θ value	5.08302e-128 (rank : 8)	NC score	0.997105 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P52189	Gene names	Kcnj4, Irk3
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK3).

IRKI_HUMAN
θ value	5.44333e-122 (rank : 9)	NC score	0.995997 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	Q15756	Gene names	KCNJN1
Domain Architecture
Description	Inward rectifying K(+) channel negative regulator Kir2.2v.

IRK5_HUMAN
θ value	1.3501e-96 (rank : 10)	NC score	0.989514 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P48544, Q6DK13, Q6DK14, Q92807	Gene names	KCNJ5, GIRK4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK6_HUMAN
θ value	1.26366e-94 (rank : 11)	NC score	0.988940 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

IRK5_MOUSE
θ value	1.65039e-94 (rank : 12)	NC score	0.989591 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48545, P97508	Gene names	Kcnj5, Girk4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK9_HUMAN
θ value	8.19079e-94 (rank : 13)	NC score	0.990537 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q92806, Q5JW75	Gene names	KCNJ9, GIRK3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK9_MOUSE
θ value	8.19079e-94 (rank : 14)	NC score	0.990532 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48543, Q9WUE1	Gene names	Kcnj9, Girk3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK3_HUMAN
θ value	5.30912e-93 (rank : 15)	NC score	0.988584 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK3_MOUSE
θ value	6.93392e-93 (rank : 16)	NC score	0.988610 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P63250, P35562	Gene names	Kcnj3, Girk1
Domain Architecture	No domain graphic available
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK6_MOUSE
θ value	7.17548e-90 (rank : 17)	NC score	0.988490 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P48542, O70290, P70216, P70306, P70307, P70308, P70309, P70454, Q9QYH5	Gene names	Kcnj6, Girk2, Kcnj7, W
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2).

IRK16_MOUSE
θ value	3.81361e-83 (rank : 18)	NC score	0.988299 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z307	Gene names	Kcnj16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK11_HUMAN
θ value	1.10959e-82 (rank : 19)	NC score	0.986943 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14654, Q58EX3	Gene names	KCNJ11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2) (IKATP).

IRK16_HUMAN
θ value	1.89267e-82 (rank : 20)	NC score	0.988113 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPI9	Gene names	KCNJ16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK11_MOUSE
θ value	1.60224e-81 (rank : 21)	NC score	0.986949 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q61743, Q9QX21	Gene names	Kcnj11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2).

IRK8_MOUSE
θ value	1.8332e-77 (rank : 22)	NC score	0.985641 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P97794	Gene names	Kcnj8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

IRK8_HUMAN
θ value	2.02684e-76 (rank : 23)	NC score	0.985697 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	Q15842, O00657	Gene names	KCNJ8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

IRK1_MOUSE
θ value	4.99229e-75 (rank : 24)	NC score	0.985808 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	O88335	Gene names	Kcnj1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK1_HUMAN
θ value	5.51964e-74 (rank : 25)	NC score	0.985614 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48048, Q6LD67	Gene names	KCNJ1, ROMK1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK10_HUMAN
θ value	1.90147e-66 (rank : 26)	NC score	0.978580 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P78508, Q8N4I7, Q92808	Gene names	KCNJ10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassium channel Kir4.1).

IRK10_MOUSE
θ value	3.24342e-66 (rank : 27)	NC score	0.978698 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JM63	Gene names	Kcnj10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1).

IRK15_HUMAN
θ value	3.96481e-64 (rank : 28)	NC score	0.979017 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q99712, O00564, Q96L28, Q99446	Gene names	KCNJ15, KCNJ14
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2) (Kir1.3).

IRK15_MOUSE
θ value	6.76295e-64 (rank : 29)	NC score	0.979009 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	O88932, Q9JK34	Gene names	Kcnj15
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2).

IRK13_HUMAN
θ value	3.72821e-46 (rank : 30)	NC score	0.974096 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

EXO1_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.010145 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

EXO1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.010273 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

LAC1_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.000794 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	P01843	Gene names
Domain Architecture
Description	Ig lambda-1 chain C region.

NOTC3_HUMAN
θ value	6.88961 (rank : 34)	NC score	-0.003215 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	1062	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOX5_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.003538 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

ITAE_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.005630 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P38570, Q9NZU9	Gene names	ITGAE
Domain Architecture
Description	Integrin alpha-E precursor (Mucosal lymphocyte 1 antigen) (HML-1 antigen) (Integrin alpha-IEL) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

Hits sorted by NC score

IRK14_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK14_MOUSE
NC score	0.999876 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	31
SwissProt Accessions	Q8JZN3, Q8BMK3, Q8BXM0	Gene names	Kcnj14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

IRK4_HUMAN
NC score	0.997165 (rank : 3)	θ value	1.02419e-128 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	P48050	Gene names	KCNJ4
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (Hippocampal inward rectifier) (HIR) (HRK1) (HIRK2).

IRK4_MOUSE
NC score	0.997105 (rank : 4)	θ value	5.08302e-128 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	38	Shared Neighborhood Hits	30
SwissProt Accessions	P52189	Gene names	Kcnj4, Irk3
Domain Architecture
Description	Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) (IRK3).

IRK2_HUMAN
NC score	0.996794 (rank : 5)	θ value	9.54178e-143 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	30
SwissProt Accessions	P63252, O15110, P48049	Gene names	KCNJ2, HIRK1
Domain Architecture	No domain graphic available
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (Cardiac inward rectifier potassium channel) (IRK1).

IRK2_MOUSE
NC score	0.996441 (rank : 6)	θ value	2.77624e-142 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	30
SwissProt Accessions	P35561	Gene names	Kcnj2, Irk1
Domain Architecture
Description	Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1).

IRK12_HUMAN
NC score	0.996399 (rank : 7)	θ value	1.20984e-129 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14500, O43401, Q8NG63	Gene names	KCNJ12, IRK2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRK12_MOUSE
NC score	0.996232 (rank : 8)	θ value	7.84197e-129 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	P52187, Q9QYF2	Gene names	Kcnj12, Irk2
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 12 (Potassium channel, inwardly rectifying subfamily J member 12) (Inward rectifier K(+) channel Kir2.2) (IRK2).

IRKI_HUMAN
NC score	0.995997 (rank : 9)	θ value	5.44333e-122 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	Q15756	Gene names	KCNJN1
Domain Architecture
Description	Inward rectifying K(+) channel negative regulator Kir2.2v.

IRK9_HUMAN
NC score	0.990537 (rank : 10)	θ value	8.19079e-94 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q92806, Q5JW75	Gene names	KCNJ9, GIRK3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK9_MOUSE
NC score	0.990532 (rank : 11)	θ value	8.19079e-94 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48543, Q9WUE1	Gene names	Kcnj9, Girk3
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 3 (GIRK3) (Potassium channel, inwardly rectifying subfamily J member 9) (Inwardly rectifier K(+) channel Kir3.3).

IRK5_MOUSE
NC score	0.989591 (rank : 12)	θ value	1.65039e-94 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48545, P97508	Gene names	Kcnj5, Girk4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK5_HUMAN
NC score	0.989514 (rank : 13)	θ value	1.3501e-96 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P48544, Q6DK13, Q6DK14, Q92807	Gene names	KCNJ5, GIRK4
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying subfamily J member 5) (Inward rectifier K(+) channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR).

IRK6_HUMAN
NC score	0.988940 (rank : 14)	θ value	1.26366e-94 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	33	Shared Neighborhood Hits	30
SwissProt Accessions	P48051, Q53WW6	Gene names	KCNJ6, GIRK2, KATP2, KCNJ7
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) (KATP-2) (BIR1).

IRK3_MOUSE
NC score	0.988610 (rank : 15)	θ value	6.93392e-93 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P63250, P35562	Gene names	Kcnj3, Girk1
Domain Architecture	No domain graphic available
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK3_HUMAN
NC score	0.988584 (rank : 16)	θ value	5.30912e-93 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	37	Shared Neighborhood Hits	30
SwissProt Accessions	P48549, Q8TBI0	Gene names	KCNJ3, GIRK1
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).

IRK6_MOUSE
NC score	0.988490 (rank : 17)	θ value	7.17548e-90 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P48542, O70290, P70216, P70306, P70307, P70308, P70309, P70454, Q9QYH5	Gene names	Kcnj6, Girk2, Kcnj7, W
Domain Architecture
Description	G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2).

IRK16_MOUSE
NC score	0.988299 (rank : 18)	θ value	3.81361e-83 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z307	Gene names	Kcnj16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK16_HUMAN
NC score	0.988113 (rank : 19)	θ value	1.89267e-82 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NPI9	Gene names	KCNJ16
Domain Architecture
Description	Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1).

IRK11_MOUSE
NC score	0.986949 (rank : 20)	θ value	1.60224e-81 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	32	Shared Neighborhood Hits	30
SwissProt Accessions	Q61743, Q9QX21	Gene names	Kcnj11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2).

IRK11_HUMAN
NC score	0.986943 (rank : 21)	θ value	1.10959e-82 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	Q14654, Q58EX3	Gene names	KCNJ11
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2) (IKATP).

IRK1_MOUSE
NC score	0.985808 (rank : 22)	θ value	4.99229e-75 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	O88335	Gene names	Kcnj1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK8_HUMAN
NC score	0.985697 (rank : 23)	θ value	2.02684e-76 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	Q15842, O00657	Gene names	KCNJ8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

IRK8_MOUSE
NC score	0.985641 (rank : 24)	θ value	1.8332e-77 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	34	Shared Neighborhood Hits	30
SwissProt Accessions	P97794	Gene names	Kcnj8
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) (uKATP-1).

IRK1_HUMAN
NC score	0.985614 (rank : 25)	θ value	5.51964e-74 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	31	Shared Neighborhood Hits	30
SwissProt Accessions	P48048, Q6LD67	Gene names	KCNJ1, ROMK1
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 1 (Potassium channel, inwardly rectifying subfamily J member 1) (ATP-regulated potassium channel ROM-K) (Kir1.1).

IRK15_HUMAN
NC score	0.979017 (rank : 26)	θ value	3.96481e-64 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q99712, O00564, Q96L28, Q99446	Gene names	KCNJ15, KCNJ14
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2) (Kir1.3).

IRK15_MOUSE
NC score	0.979009 (rank : 27)	θ value	6.76295e-64 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	30
SwissProt Accessions	O88932, Q9JK34	Gene names	Kcnj15
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 15 (Potassium channel, inwardly rectifying subfamily J member 15) (Inward rectifier K(+) channel Kir4.2).

IRK10_MOUSE
NC score	0.978698 (rank : 28)	θ value	3.24342e-66 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JM63	Gene names	Kcnj10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir4.1).

IRK10_HUMAN
NC score	0.978580 (rank : 29)	θ value	1.90147e-66 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	40	Shared Neighborhood Hits	31
SwissProt Accessions	P78508, Q8N4I7, Q92808	Gene names	KCNJ10
Domain Architecture
Description	ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) (ATP-dependent inwardly rectifying potassium channel Kir4.1).

IRK13_HUMAN
NC score	0.974096 (rank : 30)	θ value	3.72821e-46 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	30
SwissProt Accessions	O60928, O76023, Q8N3Y4	Gene names	KCNJ13
Domain Architecture
Description	Inward rectifier potassium channel 13 (Potassium channel, inwardly rectifying subfamily J member 13) (Inward rectifier K(+) channel Kir7.1).

EXO1_MOUSE
NC score	0.010273 (rank : 31)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

EXO1_HUMAN
NC score	0.010145 (rank : 32)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

ITAE_HUMAN
NC score	0.005630 (rank : 33)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P38570, Q9NZU9	Gene names	ITGAE
Domain Architecture
Description	Integrin alpha-E precursor (Mucosal lymphocyte 1 antigen) (HML-1 antigen) (Integrin alpha-IEL) (CD103 antigen) [Contains: Integrin alpha-E light chain; Integrin alpha-E heavy chain].

NOX5_HUMAN
NC score	0.003538 (rank : 34)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

LAC1_MOUSE
NC score	0.000794 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	P01843	Gene names
Domain Architecture
Description	Ig lambda-1 chain C region.

NOTC3_HUMAN
NC score	-0.003215 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	1062	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].