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Network neighborhood for query Sequence : EXO1_MOUSE

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EXO1_MOUSE
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXO1_HUMAN
θ value	0 (rank : 1)	NC score	0.955221 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

EXO1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

FEN1_HUMAN
θ value	2.5182e-18 (rank : 3)	NC score	0.589826 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).

FEN1_MOUSE
θ value	5.25075e-16 (rank : 4)	NC score	0.576834 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	P39749	Gene names	Fen1, Fen-1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1).

DSPP_MOUSE
θ value	4.92598e-06 (rank : 5)	NC score	0.161015 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

ERCC5_MOUSE
θ value	3.19293e-05 (rank : 6)	NC score	0.279759 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ERCC5_HUMAN
θ value	9.29e-05 (rank : 7)	NC score	0.275711 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

DSPP_HUMAN
θ value	0.00665767 (rank : 8)	NC score	0.135877 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	645	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SRRM2_MOUSE
θ value	0.0563607 (rank : 9)	NC score	0.059647 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CHD1_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.032024 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

PININ_MOUSE
θ value	0.125558 (rank : 11)	NC score	0.052815 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	777	Shared Neighborhood Hits	18
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

MUC13_MOUSE
θ value	0.163984 (rank : 12)	NC score	0.053032 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PPRB_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.068110 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	311	Shared Neighborhood Hits	17
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

BRPF1_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.035957 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	259	Shared Neighborhood Hits	9
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

DMP1_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.127106 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	498	Shared Neighborhood Hits	23
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

NCOA3_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.049435 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
θ value	0.279714 (rank : 17)	NC score	0.054687 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

ELK4_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.024173 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

PAX3_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.018629 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	513	Shared Neighborhood Hits	8
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PCX1_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.050595 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

PININ_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.044892 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PPIG_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.029210 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	670	Shared Neighborhood Hits	21
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TMCC1_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.026337 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	315	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

CM007_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.039750 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	422	Shared Neighborhood Hits	10
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

MBB1A_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.037943 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	665	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MYO9B_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.014274 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	641	Shared Neighborhood Hits	20
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TSKS_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.053129 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

NRG2_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.023321 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

PAX3_MOUSE
θ value	1.06291 (rank : 29)	NC score	0.016618 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	478	Shared Neighborhood Hits	6
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

SFRS4_MOUSE
θ value	1.06291 (rank : 30)	NC score	0.029999 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

TSKS_HUMAN
θ value	1.38821 (rank : 31)	NC score	0.048947 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

DMP1_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.093120 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

HIPK3_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.006002 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	857	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

APC_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.033027 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	603	Shared Neighborhood Hits	15
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CHD9_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.022147 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

MUC1_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.040061 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PPRB_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.063528 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	354	Shared Neighborhood Hits	24
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

AKAP6_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.034523 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	263	Shared Neighborhood Hits	15
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

C163B_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.012624 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

CD2L7_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.004538 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	1275	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CYLC1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.025654 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

MACF1_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.010510 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	1341	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.012927 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	1321	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

RBM15_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.023729 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	309	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

RIN3_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.022048 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

ACINU_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.037017 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ANR12_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.008844 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	1081	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CUL4B_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.012848 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

K0226_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.023331 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

M2GD_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.036877 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBT9, Q8R1S7	Gene names	Dmgdh
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

NELFE_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.025286 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

NF2L1_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.016119 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

PPR3A_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.029635 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MR9, Q8BUJ4, Q8BUL0	Gene names	Ppp1r3a, Pp1g
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RGL).

RNPS1_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.027831 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.027831 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SACS_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.018756 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

SC5A3_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.018224 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

SPRL1_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.026892 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

CB021_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.022303 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLN6, Q8BJN5, Q8BLP6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf21 homolog.

CD2L5_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.002997 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	1011	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

FAK2_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.001316 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	851	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

GTSE1_MOUSE
θ value	5.27518 (rank : 62)	NC score	0.022200 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	245	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

IL16_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.014035 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IRK14_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.010273 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

M2GD_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.034493 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

PKCB1_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.021364 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	488	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SC5A3_MOUSE
θ value	5.27518 (rank : 67)	NC score	0.017239 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

TR240_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.016472 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

ACCN3_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.009049 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q6X1Y6, Q7TQH4	Gene names	Accn3, Asic3, Drasic
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 3 (Acid-sensing ion channel 3) (ASIC3) (Dorsal root ASIC) (DRASIC).

AFF1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.017006 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

DPOLZ_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.019588 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

JHD2B_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.011558 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

PTN13_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.012568 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	471	Shared Neighborhood Hits	20
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SFRS4_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.022790 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	384	Shared Neighborhood Hits	18
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

WHRN_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.009973 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	412	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

ZCPW1_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.017316 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

BAZ2B_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.016058 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	803	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

CHD9_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.021523 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

GP179_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.018868 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

I10R1_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.014425 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q13651	Gene names	IL10RA, IL10R
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

K0240_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.017533 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	211	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

K1267_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.015789 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

LRP12_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.004834 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MACOI_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.009230 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

NCOA2_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.037826 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NR1D1_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.004458 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

NUDT8_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.054481 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WV74, Q6ZW59	Gene names	NUDT8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

RBP2_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.012511 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

SRRM2_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.055243 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	1296	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

IWS1_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.058519 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	1241	Shared Neighborhood Hits	36
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

Hits sorted by NC score

EXO1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	89	Target Neighborhood Hits	89	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

EXO1_HUMAN
NC score	0.955221 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	89	Target Neighborhood Hits	82	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

FEN1_HUMAN
NC score	0.589826 (rank : 3)	θ value	2.5182e-18 (rank : 3)
Query Neighborhood Hits	89	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).

FEN1_MOUSE
NC score	0.576834 (rank : 4)	θ value	5.25075e-16 (rank : 4)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	P39749	Gene names	Fen1, Fen-1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1).

ERCC5_MOUSE
NC score	0.279759 (rank : 5)	θ value	3.19293e-05 (rank : 6)
Query Neighborhood Hits	89	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ERCC5_HUMAN
NC score	0.275711 (rank : 6)	θ value	9.29e-05 (rank : 7)
Query Neighborhood Hits	89	Target Neighborhood Hits	162	Shared Neighborhood Hits	9
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

DSPP_MOUSE
NC score	0.161015 (rank : 7)	θ value	4.92598e-06 (rank : 5)
Query Neighborhood Hits	89	Target Neighborhood Hits	491	Shared Neighborhood Hits	25
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.135877 (rank : 8)	θ value	0.00665767 (rank : 8)
Query Neighborhood Hits	89	Target Neighborhood Hits	645	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DMP1_MOUSE
NC score	0.127106 (rank : 9)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	89	Target Neighborhood Hits	498	Shared Neighborhood Hits	23
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

DMP1_HUMAN
NC score	0.093120 (rank : 10)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	89	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

PPRB_HUMAN
NC score	0.068110 (rank : 11)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	89	Target Neighborhood Hits	311	Shared Neighborhood Hits	17
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

PPRB_MOUSE
NC score	0.063528 (rank : 12)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	89	Target Neighborhood Hits	354	Shared Neighborhood Hits	24
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

SRRM2_MOUSE
NC score	0.059647 (rank : 13)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	89	Target Neighborhood Hits	1470	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

IWS1_HUMAN
NC score	0.058519 (rank : 14)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	89	Target Neighborhood Hits	1241	Shared Neighborhood Hits	36
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SRRM2_HUMAN
NC score	0.055243 (rank : 15)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	89	Target Neighborhood Hits	1296	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NCOA3_MOUSE
NC score	0.054687 (rank : 16)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	89	Target Neighborhood Hits	203	Shared Neighborhood Hits	14
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NUDT8_HUMAN
NC score	0.054481 (rank : 17)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	89	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WV74, Q6ZW59	Gene names	NUDT8
Domain Architecture	No domain graphic available
Description	Nucleoside diphosphate-linked moiety X motif 8, mitochondrial precursor (EC 3.6.1.-) (Nudix motif 8).

TSKS_MOUSE
NC score	0.053129 (rank : 18)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	89	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	O54887	Gene names	Stk22s1, Tsks
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

MUC13_MOUSE
NC score	0.053032 (rank : 19)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	89	Target Neighborhood Hits	447	Shared Neighborhood Hits	11
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

PININ_MOUSE
NC score	0.052815 (rank : 20)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	89	Target Neighborhood Hits	777	Shared Neighborhood Hits	18
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

PCX1_HUMAN
NC score	0.050595 (rank : 21)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	89	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

NCOA3_HUMAN
NC score	0.049435 (rank : 22)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	89	Target Neighborhood Hits	171	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

TSKS_HUMAN
NC score	0.048947 (rank : 23)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	89	Target Neighborhood Hits	220	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

PININ_HUMAN
NC score	0.044892 (rank : 24)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	89	Target Neighborhood Hits	753	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

MUC1_MOUSE
NC score	0.040061 (rank : 25)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	89	Target Neighborhood Hits	388	Shared Neighborhood Hits	11
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CM007_HUMAN
NC score	0.039750 (rank : 26)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	89	Target Neighborhood Hits	422	Shared Neighborhood Hits	10
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

MBB1A_HUMAN
NC score	0.037943 (rank : 27)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	89	Target Neighborhood Hits	665	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NCOA2_HUMAN
NC score	0.037826 (rank : 28)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	89	Target Neighborhood Hits	281	Shared Neighborhood Hits	17
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

ACINU_HUMAN
NC score	0.037017 (rank : 29)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	89	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

M2GD_MOUSE
NC score	0.036877 (rank : 30)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBT9, Q8R1S7	Gene names	Dmgdh
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

BRPF1_HUMAN
NC score	0.035957 (rank : 31)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	89	Target Neighborhood Hits	259	Shared Neighborhood Hits	9
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

AKAP6_HUMAN
NC score	0.034523 (rank : 32)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	89	Target Neighborhood Hits	263	Shared Neighborhood Hits	15
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

M2GD_HUMAN
NC score	0.034493 (rank : 33)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	89	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI17	Gene names	DMGDH
Domain Architecture
Description	Dimethylglycine dehydrogenase, mitochondrial precursor (EC 1.5.99.2) (ME2GLYDH).

APC_HUMAN
NC score	0.033027 (rank : 34)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	89	Target Neighborhood Hits	603	Shared Neighborhood Hits	15
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CHD1_HUMAN
NC score	0.032024 (rank : 35)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	89	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SFRS4_MOUSE
NC score	0.029999 (rank : 36)	θ value	1.06291 (rank : 30)
Query Neighborhood Hits	89	Target Neighborhood Hits	406	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

PPR3A_MOUSE
NC score	0.029635 (rank : 37)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	89	Target Neighborhood Hits	45	Shared Neighborhood Hits	6
SwissProt Accessions	Q99MR9, Q8BUJ4, Q8BUL0	Gene names	Ppp1r3a, Pp1g
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RGL).

PPIG_HUMAN
NC score	0.029210 (rank : 38)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	89	Target Neighborhood Hits	670	Shared Neighborhood Hits	21
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RNPS1_HUMAN
NC score	0.027831 (rank : 39)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	89	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.027831 (rank : 40)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	89	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

SPRL1_MOUSE
NC score	0.026892 (rank : 41)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	89	Target Neighborhood Hits	403	Shared Neighborhood Hits	14
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TMCC1_MOUSE
NC score	0.026337 (rank : 42)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	89	Target Neighborhood Hits	315	Shared Neighborhood Hits	4
SwissProt Accessions	Q69ZZ6, Q8CEF4	Gene names	Tmcc1, Kiaa0779
Domain Architecture	No domain graphic available
Description	Transmembrane and coiled-coil domains protein 1.

CYLC1_HUMAN
NC score	0.025654 (rank : 43)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	89	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

NELFE_HUMAN
NC score	0.025286 (rank : 44)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	89	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	P18615, Q5JP74, Q5JP75, Q96F56, Q9NPK2	Gene names	RDBP, NELFE, RD
Domain Architecture
Description	Negative elongation factor E (NELF-E) (RD protein).

ELK4_HUMAN
NC score	0.024173 (rank : 45)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	89	Target Neighborhood Hits	184	Shared Neighborhood Hits	3
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

RBM15_HUMAN
NC score	0.023729 (rank : 46)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	89	Target Neighborhood Hits	309	Shared Neighborhood Hits	14
SwissProt Accessions	Q96T37, Q5D058, Q96PE4, Q96SC5, Q96SC6, Q96SC9, Q96SD0, Q96T38, Q9BRA5, Q9H6R8, Q9H9Y0	Gene names	RBM15, OTT
Domain Architecture
Description	Putative RNA-binding protein 15 (RNA-binding motif protein 15) (One- twenty two protein).

K0226_HUMAN
NC score	0.023331 (rank : 47)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	89	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	Q92622	Gene names	KIAA0226
Domain Architecture	No domain graphic available
Description	Protein KIAA0226.

NRG2_HUMAN
NC score	0.023321 (rank : 48)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	89	Target Neighborhood Hits	419	Shared Neighborhood Hits	5
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

SFRS4_HUMAN
NC score	0.022790 (rank : 49)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	89	Target Neighborhood Hits	384	Shared Neighborhood Hits	18
SwissProt Accessions	Q08170, Q5VXP1, Q9BUA4, Q9UEB5	Gene names	SFRS4, SRP75
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB).

CB021_MOUSE
NC score	0.022303 (rank : 50)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	89	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLN6, Q8BJN5, Q8BLP6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf21 homolog.

GTSE1_MOUSE
NC score	0.022200 (rank : 51)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	89	Target Neighborhood Hits	245	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

CHD9_HUMAN
NC score	0.022147 (rank : 52)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	89	Target Neighborhood Hits	343	Shared Neighborhood Hits	14
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

RIN3_HUMAN
NC score	0.022048 (rank : 53)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	89	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

CHD9_MOUSE
NC score	0.021523 (rank : 54)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	89	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

PKCB1_HUMAN
NC score	0.021364 (rank : 55)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	89	Target Neighborhood Hits	488	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

DPOLZ_MOUSE
NC score	0.019588 (rank : 56)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	89	Target Neighborhood Hits	169	Shared Neighborhood Hits	12
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

GP179_HUMAN
NC score	0.018868 (rank : 57)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	89	Target Neighborhood Hits	372	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

SACS_MOUSE
NC score	0.018756 (rank : 58)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLC8	Gene names	Sacs
Domain Architecture
Description	Sacsin.

PAX3_HUMAN
NC score	0.018629 (rank : 59)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	89	Target Neighborhood Hits	513	Shared Neighborhood Hits	8
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

SC5A3_HUMAN
NC score	0.018224 (rank : 60)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	89	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P53794, O43489	Gene names	SLC5A3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

K0240_MOUSE
NC score	0.017533 (rank : 61)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	89	Target Neighborhood Hits	211	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

ZCPW1_MOUSE
NC score	0.017316 (rank : 62)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	89	Target Neighborhood Hits	307	Shared Neighborhood Hits	8
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

SC5A3_MOUSE
NC score	0.017239 (rank : 63)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	89	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JKZ2	Gene names	Slc5a3
Domain Architecture
Description	Sodium/myo-inositol cotransporter (Na(+)/myo-inositol cotransporter).

AFF1_HUMAN
NC score	0.017006 (rank : 64)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	89	Target Neighborhood Hits	506	Shared Neighborhood Hits	18
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

PAX3_MOUSE
NC score	0.016618 (rank : 65)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	89	Target Neighborhood Hits	478	Shared Neighborhood Hits	6
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

TR240_HUMAN
NC score	0.016472 (rank : 66)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	89	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

NF2L1_MOUSE
NC score	0.016119 (rank : 67)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	89	Target Neighborhood Hits	185	Shared Neighborhood Hits	3
SwissProt Accessions	Q61985, O70234	Gene names	Nfe2l1, Nrf1
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1).

BAZ2B_HUMAN
NC score	0.016058 (rank : 68)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	89	Target Neighborhood Hits	803	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

K1267_HUMAN
NC score	0.015789 (rank : 69)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	89	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

I10R1_HUMAN
NC score	0.014425 (rank : 70)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	89	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q13651	Gene names	IL10RA, IL10R
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

MYO9B_HUMAN
NC score	0.014274 (rank : 71)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	89	Target Neighborhood Hits	641	Shared Neighborhood Hits	20
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

IL16_HUMAN
NC score	0.014035 (rank : 72)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	89	Target Neighborhood Hits	207	Shared Neighborhood Hits	7
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

MACF4_HUMAN
NC score	0.012927 (rank : 73)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	89	Target Neighborhood Hits	1321	Shared Neighborhood Hits	16
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CUL4B_HUMAN
NC score	0.012848 (rank : 74)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	89	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

C163B_HUMAN
NC score	0.012624 (rank : 75)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	89	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

PTN13_HUMAN
NC score	0.012568 (rank : 76)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	89	Target Neighborhood Hits	471	Shared Neighborhood Hits	20
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

RBP2_MOUSE
NC score	0.012511 (rank : 77)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	89	Target Neighborhood Hits	232	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

JHD2B_MOUSE
NC score	0.011558 (rank : 78)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	89	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q6ZPY7, Q2VPQ5, Q5U5V7, Q6P9K3, Q8CCE2, Q8K2A5, Q9CU57	Gene names	Jmjd1b, Jhdm2b, Kiaa1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B).

MACF1_HUMAN
NC score	0.010510 (rank : 79)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	89	Target Neighborhood Hits	1341	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

IRK14_HUMAN
NC score	0.010273 (rank : 80)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	89	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UNX9	Gene names	KCNJ14
Domain Architecture	No domain graphic available
Description	ATP-sensitive inward rectifier potassium channel 14 (Potassium channel, inwardly rectifying subfamily J member 14) (Inward rectifier K(+) channel Kir2.4) (IRK4).

WHRN_MOUSE
NC score	0.009973 (rank : 81)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	89	Target Neighborhood Hits	412	Shared Neighborhood Hits	9
SwissProt Accessions	Q80VW5, Q80TC2, Q80VW4	Gene names	Whrn, Kiaa1526
Domain Architecture	No domain graphic available
Description	Whirlin.

MACOI_HUMAN
NC score	0.009230 (rank : 82)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	89	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5G2, Q2TLX5, Q2TLX6, Q9NVG6	Gene names	TMEM57
Domain Architecture	No domain graphic available
Description	Macoilin (Transmembrane protein 57).

ACCN3_MOUSE
NC score	0.009049 (rank : 83)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	89	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q6X1Y6, Q7TQH4	Gene names	Accn3, Asic3, Drasic
Domain Architecture	No domain graphic available
Description	Amiloride-sensitive cation channel 3 (Acid-sensing ion channel 3) (ASIC3) (Dorsal root ASIC) (DRASIC).

ANR12_HUMAN
NC score	0.008844 (rank : 84)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	89	Target Neighborhood Hits	1081	Shared Neighborhood Hits	18
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

HIPK3_MOUSE
NC score	0.006002 (rank : 85)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	89	Target Neighborhood Hits	857	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

LRP12_HUMAN
NC score	0.004834 (rank : 86)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	89	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CD2L7_HUMAN
NC score	0.004538 (rank : 87)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	89	Target Neighborhood Hits	1275	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

NR1D1_HUMAN
NC score	0.004458 (rank : 88)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	89	Target Neighborhood Hits	140	Shared Neighborhood Hits	4
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

CD2L5_MOUSE
NC score	0.002997 (rank : 89)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	89	Target Neighborhood Hits	1011	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

FAK2_MOUSE
NC score	0.001316 (rank : 90)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	89	Target Neighborhood Hits	851	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).