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Network neighborhood for query Sequence : FEN1_HUMAN

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FEN1_HUMAN
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FEN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).

FEN1_MOUSE
θ value	3.82926e-184 (rank : 2)	NC score	0.998090 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P39749	Gene names	Fen1, Fen-1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1).

EXO1_HUMAN
θ value	8.65492e-19 (rank : 3)	NC score	0.588467 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

EXO1_MOUSE
θ value	2.5182e-18 (rank : 4)	NC score	0.589826 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

ERCC5_MOUSE
θ value	1.42992e-13 (rank : 5)	NC score	0.486712 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

ERCC5_HUMAN
θ value	9.26847e-13 (rank : 6)	NC score	0.491835 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

RAI14_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.015615 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	1505	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

LRC45_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.024147 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	933	Shared Neighborhood Hits	6
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

OLR1_MOUSE
θ value	2.36792 (rank : 9)	NC score	0.026439 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

SPAG5_HUMAN
θ value	3.0926 (rank : 10)	NC score	0.017193 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	625	Shared Neighborhood Hits	5
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

NIM1_HUMAN
θ value	8.99809 (rank : 11)	NC score	-0.000093 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	850	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

NUCB2_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.019227 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	459	Shared Neighborhood Hits	4
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

Hits sorted by NC score

FEN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	P39748	Gene names	FEN1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1) (Maturation factor 1) (MF1) (hFEN-1) (DNase IV).

FEN1_MOUSE
NC score	0.998090 (rank : 2)	θ value	3.82926e-184 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P39749	Gene names	Fen1, Fen-1
Domain Architecture
Description	Flap endonuclease 1 (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (FEN-1).

EXO1_MOUSE
NC score	0.589826 (rank : 3)	θ value	2.5182e-18 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	89	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

EXO1_HUMAN
NC score	0.588467 (rank : 4)	θ value	8.65492e-19 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UQ84, O60545, O75214, O75466, Q5T396, Q96IJ1, Q9UG38, Q9UNW0	Gene names	EXO1, EXOI, HEX1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (hExo1) (Exonuclease I) (hExoI).

ERCC5_HUMAN
NC score	0.491835 (rank : 5)	θ value	9.26847e-13 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

ERCC5_MOUSE
NC score	0.486712 (rank : 6)	θ value	1.42992e-13 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	206	Shared Neighborhood Hits	7
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

OLR1_MOUSE
NC score	0.026439 (rank : 7)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	596	Shared Neighborhood Hits	6
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

LRC45_HUMAN
NC score	0.024147 (rank : 8)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	933	Shared Neighborhood Hits	6
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NUCB2_MOUSE
NC score	0.019227 (rank : 9)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	459	Shared Neighborhood Hits	4
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

SPAG5_HUMAN
NC score	0.017193 (rank : 10)	θ value	3.0926 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	625	Shared Neighborhood Hits	5
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

RAI14_MOUSE
NC score	0.015615 (rank : 11)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	1505	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

NIM1_HUMAN
NC score	-0.000093 (rank : 12)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	850	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).