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Network neighborhood for query Sequence : TR240_HUMAN

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TR240_HUMAN
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

T240L_HUMAN
θ value	0 (rank : 1)	NC score	0.943001 (rank : 2)
Query Neighborhood Hits	99	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_MOUSE
θ value	0 (rank : 2)	NC score	0.940520 (rank : 3)
Query Neighborhood Hits	99	Target Neighborhood Hits	143	Shared Neighborhood Hits	13
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

TR240_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

SREC2_HUMAN
θ value	0.0431538 (rank : 4)	NC score	0.025002 (rank : 32)
Query Neighborhood Hits	99	Target Neighborhood Hits	645	Shared Neighborhood Hits	20
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NACAM_MOUSE
θ value	0.0736092 (rank : 5)	NC score	0.056857 (rank : 4)
Query Neighborhood Hits	99	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

UBP42_HUMAN
θ value	0.0961366 (rank : 6)	NC score	0.029864 (rank : 19)
Query Neighborhood Hits	99	Target Neighborhood Hits	445	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

ATX7_HUMAN
θ value	0.125558 (rank : 7)	NC score	0.054438 (rank : 6)
Query Neighborhood Hits	99	Target Neighborhood Hits	351	Shared Neighborhood Hits	16
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

MTSS1_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.050894 (rank : 7)
Query Neighborhood Hits	99	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

ANK3_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.015493 (rank : 64)
Query Neighborhood Hits	99	Target Neighborhood Hits	853	Shared Neighborhood Hits	21
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MAGD4_HUMAN
θ value	0.21417 (rank : 10)	NC score	0.024686 (rank : 35)
Query Neighborhood Hits	99	Target Neighborhood Hits	338	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

GFI1_MOUSE
θ value	0.279714 (rank : 11)	NC score	0.004180 (rank : 95)
Query Neighborhood Hits	99	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	P70338, O09063	Gene names	Gfi1, Gfi-1
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

CBP_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.037829 (rank : 11)
Query Neighborhood Hits	99	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SON_MOUSE
θ value	0.47712 (rank : 13)	NC score	0.040528 (rank : 10)
Query Neighborhood Hits	99	Target Neighborhood Hits	957	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

COHA1_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.036312 (rank : 12)
Query Neighborhood Hits	99	Target Neighborhood Hits	400	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

PGCA_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.024813 (rank : 34)
Query Neighborhood Hits	99	Target Neighborhood Hits	643	Shared Neighborhood Hits	16
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

TPX2_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.045071 (rank : 9)
Query Neighborhood Hits	99	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

DOT1L_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.046869 (rank : 8)
Query Neighborhood Hits	99	Target Neighborhood Hits	660	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

MUC1_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.030724 (rank : 16)
Query Neighborhood Hits	99	Target Neighborhood Hits	975	Shared Neighborhood Hits	28
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

TRI44_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.029862 (rank : 20)
Query Neighborhood Hits	99	Target Neighborhood Hits	393	Shared Neighborhood Hits	12
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

EGR1_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.005154 (rank : 92)
Query Neighborhood Hits	99	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

IF4G1_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.026010 (rank : 28)
Query Neighborhood Hits	99	Target Neighborhood Hits	347	Shared Neighborhood Hits	20
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

K1849_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.028292 (rank : 24)
Query Neighborhood Hits	99	Target Neighborhood Hits	335	Shared Neighborhood Hits	8
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MLL2_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.029637 (rank : 21)
Query Neighborhood Hits	99	Target Neighborhood Hits	1788	Shared Neighborhood Hits	43
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHC3_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.025130 (rank : 31)
Query Neighborhood Hits	99	Target Neighborhood Hits	218	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

TOP2B_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.026328 (rank : 27)
Query Neighborhood Hits	99	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TXND2_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.026550 (rank : 26)
Query Neighborhood Hits	99	Target Neighborhood Hits	793	Shared Neighborhood Hits	24
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CGRE1_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.030579 (rank : 17)
Query Neighborhood Hits	99	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

ENL_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.031089 (rank : 15)
Query Neighborhood Hits	99	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HCN3_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.011546 (rank : 78)
Query Neighborhood Hits	99	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

PKHG1_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.015016 (rank : 69)
Query Neighborhood Hits	99	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

SFR12_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.015868 (rank : 61)
Query Neighborhood Hits	99	Target Neighborhood Hits	553	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

TFE2_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.021739 (rank : 44)
Query Neighborhood Hits	99	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TLE3_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.018762 (rank : 52)
Query Neighborhood Hits	99	Target Neighborhood Hits	378	Shared Neighborhood Hits	16
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

TRI39_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.008387 (rank : 84)
Query Neighborhood Hits	99	Target Neighborhood Hits	691	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

VP13B_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.029320 (rank : 22)
Query Neighborhood Hits	99	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7G8, Q709C6, Q709C7, Q7Z7G4, Q7Z7G5, Q7Z7G6, Q7Z7G7, Q8NB77, Q9NWV1, Q9Y4E7	Gene names	VPS13B, CHS1, COH1, KIAA0532
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1).

WWP1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.015607 (rank : 62)
Query Neighborhood Hits	99	Target Neighborhood Hits	262	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

ZAN_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.022483 (rank : 41)
Query Neighborhood Hits	99	Target Neighborhood Hits	679	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

BRDT_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.016925 (rank : 55)
Query Neighborhood Hits	99	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

DGC14_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.026710 (rank : 25)
Query Neighborhood Hits	99	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

DOK7_MOUSE
θ value	3.0926 (rank : 40)	NC score	0.024490 (rank : 36)
Query Neighborhood Hits	99	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

ETV3_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.014549 (rank : 70)
Query Neighborhood Hits	99	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

MAP1A_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.017978 (rank : 53)
Query Neighborhood Hits	99	Target Neighborhood Hits	1626	Shared Neighborhood Hits	27
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MYT1_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.013277 (rank : 72)
Query Neighborhood Hits	99	Target Neighborhood Hits	475	Shared Neighborhood Hits	7
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

PCLO_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.030565 (rank : 18)
Query Neighborhood Hits	99	Target Neighborhood Hits	2046	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PREP_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.022330 (rank : 42)
Query Neighborhood Hits	99	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JRX3, O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6, Q9BVJ5, Q9UPP8	Gene names	PITRM1, KIAA1104, MP1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (hPreP) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1).

WEE1_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.004824 (rank : 93)
Query Neighborhood Hits	99	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

AYTL1_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.011057 (rank : 79)
Query Neighborhood Hits	99	Target Neighborhood Hits	140	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

DISC1_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.022083 (rank : 43)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q811T9, Q7TQ21, Q8CF87, Q8CF88, Q8CHP1, Q8CHP2	Gene names	Disc1
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 homolog.

FBLN2_MOUSE
θ value	4.03905 (rank : 49)	NC score	0.007958 (rank : 85)
Query Neighborhood Hits	99	Target Neighborhood Hits	505	Shared Neighborhood Hits	13
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

GOGB1_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.005607 (rank : 90)
Query Neighborhood Hits	99	Target Neighborhood Hits	2297	Shared Neighborhood Hits	27
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

K2027_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.025832 (rank : 30)
Query Neighborhood Hits	99	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MLL3_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.021013 (rank : 46)
Query Neighborhood Hits	99	Target Neighborhood Hits	1644	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TOP2B_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.023283 (rank : 38)
Query Neighborhood Hits	99	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TRI44_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.024904 (rank : 33)
Query Neighborhood Hits	99	Target Neighborhood Hits	327	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

ZC3H6_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.016584 (rank : 58)
Query Neighborhood Hits	99	Target Neighborhood Hits	239	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

ANR10_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.009365 (rank : 83)
Query Neighborhood Hits	99	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

CDKL5_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.001234 (rank : 98)
Query Neighborhood Hits	99	Target Neighborhood Hits	967	Shared Neighborhood Hits	10
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

EGR1_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.004219 (rank : 94)
Query Neighborhood Hits	99	Target Neighborhood Hits	816	Shared Neighborhood Hits	11
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

EXO1_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.016472 (rank : 59)
Query Neighborhood Hits	99	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

GCM1_MOUSE
θ value	5.27518 (rank : 60)	NC score	0.016607 (rank : 57)
Query Neighborhood Hits	99	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

MLL4_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.024100 (rank : 37)
Query Neighborhood Hits	99	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TLE3_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.016755 (rank : 56)
Query Neighborhood Hits	99	Target Neighborhood Hits	385	Shared Neighborhood Hits	15
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

ADFP_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.012544 (rank : 73)
Query Neighborhood Hits	99	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P43883	Gene names	Adfp, Adrp
Domain Architecture
Description	Adipophilin (Adipose differentiation-related protein) (ADRP).

AP3D1_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.015512 (rank : 63)
Query Neighborhood Hits	99	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

AP3D1_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.015145 (rank : 68)
Query Neighborhood Hits	99	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

CF155_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.031430 (rank : 14)
Query Neighborhood Hits	99	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W2, Q5TG13	Gene names	C6orf155
Domain Architecture	No domain graphic available
Description	Protein C6orf155.

DOK1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.012294 (rank : 75)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

FAT2_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.003917 (rank : 96)
Query Neighborhood Hits	99	Target Neighborhood Hits	507	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

K2002_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.012056 (rank : 76)
Query Neighborhood Hits	99	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

MTSS1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.034805 (rank : 13)
Query Neighborhood Hits	99	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

NADAP_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.019673 (rank : 50)
Query Neighborhood Hits	99	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

NOTC2_MOUSE
θ value	6.88961 (rank : 72)	NC score	0.006268 (rank : 88)
Query Neighborhood Hits	99	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PAK1_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.000807 (rank : 100)
Query Neighborhood Hits	99	Target Neighborhood Hits	873	Shared Neighborhood Hits	6
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).

PAK1_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.000873 (rank : 99)
Query Neighborhood Hits	99	Target Neighborhood Hits	878	Shared Neighborhood Hits	7
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

S22A3_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.007729 (rank : 86)
Query Neighborhood Hits	99	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTW5, Q9R209	Gene names	Slc22a3, Oct3
Domain Architecture
Description	Organic cation transporter 3 (Solute carrier family 22 member 3).

SAPS1_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.019606 (rank : 51)
Query Neighborhood Hits	99	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

SEM6C_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.005229 (rank : 91)
Query Neighborhood Hits	99	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

SON_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.028724 (rank : 23)
Query Neighborhood Hits	99	Target Neighborhood Hits	1568	Shared Neighborhood Hits	39
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPT5H_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.023233 (rank : 39)
Query Neighborhood Hits	99	Target Neighborhood Hits	436	Shared Neighborhood Hits	18
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.023068 (rank : 40)
Query Neighborhood Hits	99	Target Neighborhood Hits	437	Shared Neighborhood Hits	18
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

TLE4_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.015468 (rank : 66)
Query Neighborhood Hits	99	Target Neighborhood Hits	477	Shared Neighborhood Hits	13
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.015486 (rank : 65)
Query Neighborhood Hits	99	Target Neighborhood Hits	482	Shared Neighborhood Hits	13
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TRI39_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.006969 (rank : 87)
Query Neighborhood Hits	99	Target Neighborhood Hits	693	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TTLL5_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.010761 (rank : 80)
Query Neighborhood Hits	99	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

YETS2_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.020375 (rank : 47)
Query Neighborhood Hits	99	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

AXUD1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.010296 (rank : 82)
Query Neighborhood Hits	99	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P59054	Gene names	Axud1, Taip3
Domain Architecture	No domain graphic available
Description	Axin-1 up-regulated gene 1 protein (TGF-beta-induced apoptosis protein 3) (TAIP-3).

CSF1_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.016238 (rank : 60)
Query Neighborhood Hits	99	Target Neighborhood Hits	258	Shared Neighborhood Hits	11
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

FGD3_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.005999 (rank : 89)
Query Neighborhood Hits	99	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

GP112_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.010584 (rank : 81)
Query Neighborhood Hits	99	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

HTF4_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.013772 (rank : 71)
Query Neighborhood Hits	99	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

IWS1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.017140 (rank : 54)
Query Neighborhood Hits	99	Target Neighborhood Hits	1258	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K2027_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.021259 (rank : 45)
Query Neighborhood Hits	99	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MUCDL_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.019986 (rank : 49)
Query Neighborhood Hits	99	Target Neighborhood Hits	777	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

RBM12_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.025985 (rank : 29)
Query Neighborhood Hits	99	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RIMB2_HUMAN
θ value	8.99809 (rank : 95)	NC score	0.012298 (rank : 74)
Query Neighborhood Hits	99	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIMB2_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.011952 (rank : 77)
Query Neighborhood Hits	99	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

SSFA2_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.015346 (rank : 67)
Query Neighborhood Hits	99	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

TEX2_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.020117 (rank : 48)
Query Neighborhood Hits	99	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

TRIPB_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.003368 (rank : 97)
Query Neighborhood Hits	99	Target Neighborhood Hits	1587	Shared Neighborhood Hits	17
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

FM30A_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.055072 (rank : 5)
Query Neighborhood Hits	99	Target Neighborhood Hits	9	Shared Neighborhood Hits	1
SwissProt Accessions	Q9NZY2	Gene names	FAM30A, C14orf110
Domain Architecture	No domain graphic available
Description	Protein FAM30A.

Hits sorted by NC score

TR240_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	99	Target Neighborhood Hits	99	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

T240L_HUMAN
NC score	0.943001 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	99	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

T240L_MOUSE
NC score	0.940520 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	99	Target Neighborhood Hits	143	Shared Neighborhood Hits	13
SwissProt Accessions	Q6JPI3, Q3TRF4, Q3UQI8, Q80TM3, Q80WQ0	Gene names	Thrap2, Kiaa1025, Trap240l
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

NACAM_MOUSE
NC score	0.056857 (rank : 4)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	99	Target Neighborhood Hits	1866	Shared Neighborhood Hits	53
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

FM30A_HUMAN
NC score	0.055072 (rank : 5)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	99	Target Neighborhood Hits	9	Shared Neighborhood Hits	1
SwissProt Accessions	Q9NZY2	Gene names	FAM30A, C14orf110
Domain Architecture	No domain graphic available
Description	Protein FAM30A.

ATX7_HUMAN
NC score	0.054438 (rank : 6)	θ value	0.125558 (rank : 7)
Query Neighborhood Hits	99	Target Neighborhood Hits	351	Shared Neighborhood Hits	16
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

MTSS1_MOUSE
NC score	0.050894 (rank : 7)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	99	Target Neighborhood Hits	592	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

DOT1L_HUMAN
NC score	0.046869 (rank : 8)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	99	Target Neighborhood Hits	660	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

TPX2_HUMAN
NC score	0.045071 (rank : 9)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	99	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

SON_MOUSE
NC score	0.040528 (rank : 10)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	99	Target Neighborhood Hits	957	Shared Neighborhood Hits	30
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CBP_MOUSE
NC score	0.037829 (rank : 11)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	99	Target Neighborhood Hits	1051	Shared Neighborhood Hits	40
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

COHA1_HUMAN
NC score	0.036312 (rank : 12)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	99	Target Neighborhood Hits	400	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

MTSS1_HUMAN
NC score	0.034805 (rank : 13)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	99	Target Neighborhood Hits	504	Shared Neighborhood Hits	17
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CF155_HUMAN
NC score	0.031430 (rank : 14)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	99	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W2, Q5TG13	Gene names	C6orf155
Domain Architecture	No domain graphic available
Description	Protein C6orf155.

ENL_HUMAN
NC score	0.031089 (rank : 15)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	99	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MUC1_HUMAN
NC score	0.030724 (rank : 16)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	99	Target Neighborhood Hits	975	Shared Neighborhood Hits	28
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CGRE1_MOUSE
NC score	0.030579 (rank : 17)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	99	Target Neighborhood Hits	173	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R1U2, Q9D1K1	Gene names	Cgref1, Cgr11
Domain Architecture	No domain graphic available
Description	Cell growth regulator with EF hand domain 1 (Cell growth regulatory gene 11 protein).

PCLO_HUMAN
NC score	0.030565 (rank : 18)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	99	Target Neighborhood Hits	2046	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

UBP42_HUMAN
NC score	0.029864 (rank : 19)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	99	Target Neighborhood Hits	445	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

TRI44_HUMAN
NC score	0.029862 (rank : 20)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	99	Target Neighborhood Hits	393	Shared Neighborhood Hits	12
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

MLL2_HUMAN
NC score	0.029637 (rank : 21)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	99	Target Neighborhood Hits	1788	Shared Neighborhood Hits	43
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

VP13B_HUMAN
NC score	0.029320 (rank : 22)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	99	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z7G8, Q709C6, Q709C7, Q7Z7G4, Q7Z7G5, Q7Z7G6, Q7Z7G7, Q8NB77, Q9NWV1, Q9Y4E7	Gene names	VPS13B, CHS1, COH1, KIAA0532
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 13B (Cohen syndrome protein 1).

SON_HUMAN
NC score	0.028724 (rank : 23)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	99	Target Neighborhood Hits	1568	Shared Neighborhood Hits	39
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

K1849_MOUSE
NC score	0.028292 (rank : 24)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	99	Target Neighborhood Hits	335	Shared Neighborhood Hits	8
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

DGC14_HUMAN
NC score	0.026710 (rank : 25)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	99	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

TXND2_HUMAN
NC score	0.026550 (rank : 26)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	99	Target Neighborhood Hits	793	Shared Neighborhood Hits	24
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TOP2B_MOUSE
NC score	0.026328 (rank : 27)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	99	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

IF4G1_HUMAN
NC score	0.026010 (rank : 28)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	99	Target Neighborhood Hits	347	Shared Neighborhood Hits	20
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

RBM12_HUMAN
NC score	0.025985 (rank : 29)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	99	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

K2027_HUMAN
NC score	0.025832 (rank : 30)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	99	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

PHC3_HUMAN
NC score	0.025130 (rank : 31)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	99	Target Neighborhood Hits	218	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

SREC2_HUMAN
NC score	0.025002 (rank : 32)	θ value	0.0431538 (rank : 4)
Query Neighborhood Hits	99	Target Neighborhood Hits	645	Shared Neighborhood Hits	20
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TRI44_MOUSE
NC score	0.024904 (rank : 33)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	99	Target Neighborhood Hits	327	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

PGCA_MOUSE
NC score	0.024813 (rank : 34)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	99	Target Neighborhood Hits	643	Shared Neighborhood Hits	16
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

MAGD4_HUMAN
NC score	0.024686 (rank : 35)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	99	Target Neighborhood Hits	338	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

DOK7_MOUSE
NC score	0.024490 (rank : 36)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	99	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

MLL4_HUMAN
NC score	0.024100 (rank : 37)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	99	Target Neighborhood Hits	722	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

TOP2B_HUMAN
NC score	0.023283 (rank : 38)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	99	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

SPT5H_HUMAN
NC score	0.023233 (rank : 39)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	99	Target Neighborhood Hits	436	Shared Neighborhood Hits	18
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
NC score	0.023068 (rank : 40)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	99	Target Neighborhood Hits	437	Shared Neighborhood Hits	18
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

ZAN_HUMAN
NC score	0.022483 (rank : 41)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	99	Target Neighborhood Hits	679	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

PREP_HUMAN
NC score	0.022330 (rank : 42)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	99	Target Neighborhood Hits	29	Shared Neighborhood Hits	4
SwissProt Accessions	Q5JRX3, O95204, Q2M2G6, Q4VBR1, Q5JRW7, Q7L5Z7, Q9BSI6, Q9BVJ5, Q9UPP8	Gene names	PITRM1, KIAA1104, MP1
Domain Architecture	No domain graphic available
Description	Presequence protease, mitochondrial precursor (EC 3.4.24.-) (hPreP) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1).

DISC1_MOUSE
NC score	0.022083 (rank : 43)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	99	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q811T9, Q7TQ21, Q8CF87, Q8CF88, Q8CHP1, Q8CHP2	Gene names	Disc1
Domain Architecture	No domain graphic available
Description	Disrupted in schizophrenia 1 homolog.

TFE2_MOUSE
NC score	0.021739 (rank : 44)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	99	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

K2027_MOUSE
NC score	0.021259 (rank : 45)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	99	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MLL3_HUMAN
NC score	0.021013 (rank : 46)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	99	Target Neighborhood Hits	1644	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

YETS2_HUMAN
NC score	0.020375 (rank : 47)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	99	Target Neighborhood Hits	212	Shared Neighborhood Hits	15
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

TEX2_HUMAN
NC score	0.020117 (rank : 48)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	99	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWB9, Q6AHZ5, Q8N3L0, Q9C0C5	Gene names	TEX2, KIAA1738
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 2 protein.

MUCDL_HUMAN
NC score	0.019986 (rank : 49)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	99	Target Neighborhood Hits	777	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

NADAP_HUMAN
NC score	0.019673 (rank : 50)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	99	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

SAPS1_HUMAN
NC score	0.019606 (rank : 51)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	99	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

TLE3_MOUSE
NC score	0.018762 (rank : 52)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	99	Target Neighborhood Hits	378	Shared Neighborhood Hits	16
SwissProt Accessions	Q08122, Q923A4	Gene names	Tle3, Esg
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG) (Grg-3).

MAP1A_HUMAN
NC score	0.017978 (rank : 53)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	99	Target Neighborhood Hits	1626	Shared Neighborhood Hits	27
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

IWS1_MOUSE
NC score	0.017140 (rank : 54)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	99	Target Neighborhood Hits	1258	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BRDT_MOUSE
NC score	0.016925 (rank : 55)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	99	Target Neighborhood Hits	243	Shared Neighborhood Hits	11
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

TLE3_HUMAN
NC score	0.016755 (rank : 56)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	99	Target Neighborhood Hits	385	Shared Neighborhood Hits	15
SwissProt Accessions	Q04726, Q8IVV6, Q8WVR2, Q9HCM5	Gene names	TLE3, KIAA1547
Domain Architecture
Description	Transducin-like enhancer protein 3 (ESG3).

GCM1_MOUSE
NC score	0.016607 (rank : 57)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	99	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P70348, O09103	Gene names	Gcm1, Gcma
Domain Architecture
Description	Chorion-specific transcription factor GCMa (Glial cells missing homolog 1) (GCM motif protein 1) (mGCMa) (mGCM1).

ZC3H6_MOUSE
NC score	0.016584 (rank : 58)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	99	Target Neighborhood Hits	239	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

EXO1_MOUSE
NC score	0.016472 (rank : 59)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	99	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

CSF1_HUMAN
NC score	0.016238 (rank : 60)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	99	Target Neighborhood Hits	258	Shared Neighborhood Hits	11
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

SFR12_HUMAN
NC score	0.015868 (rank : 61)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	99	Target Neighborhood Hits	553	Shared Neighborhood Hits	7
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

WWP1_HUMAN
NC score	0.015607 (rank : 62)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	99	Target Neighborhood Hits	262	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H0M0, O00307, Q96BP4	Gene names	WWP1
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (WW domain- containing protein 1) (Atropin-1-interacting protein 5) (AIP5).

AP3D1_HUMAN
NC score	0.015512 (rank : 63)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	99	Target Neighborhood Hits	254	Shared Neighborhood Hits	12
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

ANK3_HUMAN
NC score	0.015493 (rank : 64)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	99	Target Neighborhood Hits	853	Shared Neighborhood Hits	21
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

TLE4_MOUSE
NC score	0.015486 (rank : 65)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	99	Target Neighborhood Hits	482	Shared Neighborhood Hits	13
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.015468 (rank : 66)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	99	Target Neighborhood Hits	477	Shared Neighborhood Hits	13
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

SSFA2_HUMAN
NC score	0.015346 (rank : 67)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	99	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	P28290, Q96E36	Gene names	SSFA2, CS1
Domain Architecture	No domain graphic available
Description	Sperm-specific antigen 2 (Cleavage signal-1 protein) (CS-1).

AP3D1_MOUSE
NC score	0.015145 (rank : 68)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	99	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O54774	Gene names	Ap3d1, Ap3d
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin) (mBLVR1).

PKHG1_HUMAN
NC score	0.015016 (rank : 69)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	99	Target Neighborhood Hits	174	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

ETV3_HUMAN
NC score	0.014549 (rank : 70)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	99	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

HTF4_HUMAN
NC score	0.013772 (rank : 71)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	99	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

MYT1_HUMAN
NC score	0.013277 (rank : 72)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	99	Target Neighborhood Hits	475	Shared Neighborhood Hits	7
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

ADFP_MOUSE
NC score	0.012544 (rank : 73)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	99	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P43883	Gene names	Adfp, Adrp
Domain Architecture
Description	Adipophilin (Adipose differentiation-related protein) (ADRP).

RIMB2_HUMAN
NC score	0.012298 (rank : 74)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	99	Target Neighborhood Hits	263	Shared Neighborhood Hits	7
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

DOK1_HUMAN
NC score	0.012294 (rank : 75)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	99	Target Neighborhood Hits	85	Shared Neighborhood Hits	5
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

K2002_MOUSE
NC score	0.012056 (rank : 76)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	99	Target Neighborhood Hits	267	Shared Neighborhood Hits	4
SwissProt Accessions	Q69Z38, Q8R365	Gene names	Kiaa2002
Domain Architecture	No domain graphic available
Description	Uncharacterized tyrosine-protein kinase KIAA2002 (EC 2.7.10.2).

RIMB2_MOUSE
NC score	0.011952 (rank : 77)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	99	Target Neighborhood Hits	246	Shared Neighborhood Hits	6
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

HCN3_MOUSE
NC score	0.011546 (rank : 78)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	99	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	O88705	Gene names	Hcn3, Hac3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 (Hyperpolarization-activated cation channel 3) (HAC-3).

AYTL1_HUMAN
NC score	0.011057 (rank : 79)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	99	Target Neighborhood Hits	140	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

TTLL5_HUMAN
NC score	0.010761 (rank : 80)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	99	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

GP112_HUMAN
NC score	0.010584 (rank : 81)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	99	Target Neighborhood Hits	441	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

AXUD1_MOUSE
NC score	0.010296 (rank : 82)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	99	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	P59054	Gene names	Axud1, Taip3
Domain Architecture	No domain graphic available
Description	Axin-1 up-regulated gene 1 protein (TGF-beta-induced apoptosis protein 3) (TAIP-3).

ANR10_HUMAN
NC score	0.009365 (rank : 83)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	99	Target Neighborhood Hits	289	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

TRI39_MOUSE
NC score	0.008387 (rank : 84)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	99	Target Neighborhood Hits	691	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

FBLN2_MOUSE
NC score	0.007958 (rank : 85)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	99	Target Neighborhood Hits	505	Shared Neighborhood Hits	13
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

S22A3_MOUSE
NC score	0.007729 (rank : 86)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	99	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTW5, Q9R209	Gene names	Slc22a3, Oct3
Domain Architecture
Description	Organic cation transporter 3 (Solute carrier family 22 member 3).

TRI39_HUMAN
NC score	0.006969 (rank : 87)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	99	Target Neighborhood Hits	693	Shared Neighborhood Hits	8
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

NOTC2_MOUSE
NC score	0.006268 (rank : 88)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	99	Target Neighborhood Hits	1069	Shared Neighborhood Hits	14
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FGD3_MOUSE
NC score	0.005999 (rank : 89)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	99	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

GOGB1_HUMAN
NC score	0.005607 (rank : 90)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	99	Target Neighborhood Hits	2297	Shared Neighborhood Hits	27
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

SEM6C_HUMAN
NC score	0.005229 (rank : 91)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	99	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T2, Q5JR71, Q8WXT8, Q8WXT9, Q8WXU0, Q96JF8	Gene names	SEMA6C, KIAA1869, SEMAY
Domain Architecture
Description	Semaphorin-6C precursor (Semaphorin Y) (Sema Y).

EGR1_HUMAN
NC score	0.005154 (rank : 92)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	99	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

WEE1_MOUSE
NC score	0.004824 (rank : 93)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	99	Target Neighborhood Hits	794	Shared Neighborhood Hits	5
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

EGR1_MOUSE
NC score	0.004219 (rank : 94)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	99	Target Neighborhood Hits	816	Shared Neighborhood Hits	11
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

GFI1_MOUSE
NC score	0.004180 (rank : 95)	θ value	0.279714 (rank : 11)
Query Neighborhood Hits	99	Target Neighborhood Hits	736	Shared Neighborhood Hits	4
SwissProt Accessions	P70338, O09063	Gene names	Gfi1, Gfi-1
Domain Architecture	No domain graphic available
Description	Zinc finger protein Gfi-1 (Growth factor independence 1).

FAT2_HUMAN
NC score	0.003917 (rank : 96)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	99	Target Neighborhood Hits	507	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

TRIPB_HUMAN
NC score	0.003368 (rank : 97)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	99	Target Neighborhood Hits	1587	Shared Neighborhood Hits	17
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CDKL5_HUMAN
NC score	0.001234 (rank : 98)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	99	Target Neighborhood Hits	967	Shared Neighborhood Hits	10
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

PAK1_MOUSE
NC score	0.000873 (rank : 99)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	99	Target Neighborhood Hits	878	Shared Neighborhood Hits	7
SwissProt Accessions	O88643	Gene names	Pak1, Paka
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK) (CDC42/RAC effector kinase PAK-A).

PAK1_HUMAN
NC score	0.000807 (rank : 100)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	99	Target Neighborhood Hits	873	Shared Neighborhood Hits	6
SwissProt Accessions	Q13153, O75561, Q13567, Q32M53, Q32M54, Q86W79	Gene names	PAK1
Domain Architecture
Description	Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (p21-activated kinase 1) (PAK-1) (P65-PAK) (Alpha-PAK).