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Network neighborhood for query Sequence : TOP2B_HUMAN

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TOP2B_HUMAN
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TOP2A_HUMAN
θ value	0 (rank : 1)	NC score	0.970087 (rank : 4)
Query Neighborhood Hits	101	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2A_MOUSE
θ value	0 (rank : 2)	NC score	0.972273 (rank : 3)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2B_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	101
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_MOUSE
θ value	0 (rank : 4)	NC score	0.988656 (rank : 2)
Query Neighborhood Hits	101	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

IWS1_HUMAN
θ value	0.000461057 (rank : 5)	NC score	0.107928 (rank : 5)
Query Neighborhood Hits	101	Target Neighborhood Hits	1241	Shared Neighborhood Hits	50
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	0.000602161 (rank : 6)	NC score	0.098769 (rank : 6)
Query Neighborhood Hits	101	Target Neighborhood Hits	1258	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKA12_HUMAN
θ value	0.00390308 (rank : 7)	NC score	0.074969 (rank : 7)
Query Neighborhood Hits	101	Target Neighborhood Hits	825	Shared Neighborhood Hits	40
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ADDB_MOUSE
θ value	0.00665767 (rank : 8)	NC score	0.065832 (rank : 8)
Query Neighborhood Hits	101	Target Neighborhood Hits	574	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

PHF2_MOUSE
θ value	0.0193708 (rank : 9)	NC score	0.032821 (rank : 38)
Query Neighborhood Hits	101	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

NPAS4_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.045839 (rank : 24)
Query Neighborhood Hits	101	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

MPP8_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.031078 (rank : 41)
Query Neighborhood Hits	101	Target Neighborhood Hits	948	Shared Neighborhood Hits	30
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

FA8_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.020983 (rank : 62)
Query Neighborhood Hits	101	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

RRBP1_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.042716 (rank : 26)
Query Neighborhood Hits	101	Target Neighborhood Hits	1306	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

F10A1_HUMAN
θ value	0.47712 (rank : 14)	NC score	0.025129 (rank : 50)
Query Neighborhood Hits	101	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

AP3B2_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.039194 (rank : 27)
Query Neighborhood Hits	101	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

HTSF1_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.047483 (rank : 19)
Query Neighborhood Hits	101	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

MCM5_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.016747 (rank : 70)
Query Neighborhood Hits	101	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P33992, O60785, Q14578, Q9BTJ4, Q9BWL8	Gene names	MCM5, CDC46
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

NPAS4_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.038837 (rank : 28)
Query Neighborhood Hits	101	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PCNP_HUMAN
θ value	0.62314 (rank : 19)	NC score	0.054260 (rank : 16)
Query Neighborhood Hits	101	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WW12, Q6AI44, Q96CU3, Q9NS81	Gene names	PCNP
Domain Architecture	No domain graphic available
Description	PEST proteolytic signal-containing nuclear protein (PEST-containing nuclear protein) (PCNP).

RGS3_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.023235 (rank : 56)
Query Neighborhood Hits	101	Target Neighborhood Hits	1375	Shared Neighborhood Hits	22
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TAOK2_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.011861 (rank : 82)
Query Neighborhood Hits	101	Target Neighborhood Hits	1373	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

FA21C_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.046740 (rank : 20)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

CF206_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.052844 (rank : 18)
Query Neighborhood Hits	101	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1X1	Gene names	C6orf206, MRPS18AL1
Domain Architecture	No domain graphic available
Description	Protein C6orf206.

MEPE_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.036680 (rank : 30)
Query Neighborhood Hits	101	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

TERF2_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.060612 (rank : 9)
Query Neighborhood Hits	101	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

ZN638_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.031959 (rank : 39)
Query Neighborhood Hits	101	Target Neighborhood Hits	318	Shared Neighborhood Hits	12
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

TFAM_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.036274 (rank : 31)
Query Neighborhood Hits	101	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

TXND2_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.053676 (rank : 17)
Query Neighborhood Hits	101	Target Neighborhood Hits	793	Shared Neighborhood Hits	40
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

AF9_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.037254 (rank : 29)
Query Neighborhood Hits	101	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

AHI1_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.010917 (rank : 84)
Query Neighborhood Hits	101	Target Neighborhood Hits	537	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

CRBB3_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.017390 (rank : 69)
Query Neighborhood Hits	101	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJU9	Gene names	Crybb3
Domain Architecture
Description	Beta crystallin B3 (Beta-B3-crystallin).

DSPP_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.054523 (rank : 15)
Query Neighborhood Hits	101	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PCNP_MOUSE
θ value	1.81305 (rank : 33)	NC score	0.046574 (rank : 21)
Query Neighborhood Hits	101	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P8I4	Gene names	Pcnp
Domain Architecture	No domain graphic available
Description	PEST proteolytic signal-containing nuclear protein (PEST-containing nuclear protein) (PCNP).

TUFT1_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.017865 (rank : 68)
Query Neighborhood Hits	101	Target Neighborhood Hits	686	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CJ012_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.033449 (rank : 35)
Query Neighborhood Hits	101	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

H10_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.026765 (rank : 47)
Query Neighborhood Hits	101	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

LATS1_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.002604 (rank : 102)
Query Neighborhood Hits	101	Target Neighborhood Hits	1027	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

NOLC1_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.058012 (rank : 12)
Query Neighborhood Hits	101	Target Neighborhood Hits	452	Shared Neighborhood Hits	34
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

VPS72_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.030245 (rank : 43)
Query Neighborhood Hits	101	Target Neighborhood Hits	274	Shared Neighborhood Hits	15
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

AFF2_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.024727 (rank : 52)
Query Neighborhood Hits	101	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

CCND1_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.025690 (rank : 48)
Query Neighborhood Hits	101	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P25322	Gene names	Ccnd1, Cyl-1
Domain Architecture
Description	G1/S-specific cyclin-D1.

CDA7L_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.023333 (rank : 54)
Query Neighborhood Hits	101	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q922M5	Gene names	Cdca7l
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Transcription factor RAM2).

DSPP_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.045920 (rank : 23)
Query Neighborhood Hits	101	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HXD10_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.014723 (rank : 74)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	7
SwissProt Accessions	P28358	Gene names	HOXD10, HOX4D
Domain Architecture
Description	Homeobox protein Hox-D10 (Hox-4D) (Hox-4E).

MBB1A_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.046558 (rank : 22)
Query Neighborhood Hits	101	Target Neighborhood Hits	665	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

PARG_HUMAN
θ value	3.0926 (rank : 46)	NC score	0.034730 (rank : 33)
Query Neighborhood Hits	101	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

RECQ5_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.011606 (rank : 83)
Query Neighborhood Hits	101	Target Neighborhood Hits	390	Shared Neighborhood Hits	7
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

RRBP1_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.021521 (rank : 61)
Query Neighborhood Hits	101	Target Neighborhood Hits	1650	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SAMN1_MOUSE
θ value	3.0926 (rank : 49)	NC score	0.014726 (rank : 73)
Query Neighborhood Hits	101	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

SDPR_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.022083 (rank : 60)
Query Neighborhood Hits	101	Target Neighborhood Hits	485	Shared Neighborhood Hits	17
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

SET1A_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.028257 (rank : 46)
Query Neighborhood Hits	101	Target Neighborhood Hits	690	Shared Neighborhood Hits	24
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AHTF1_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.033291 (rank : 36)
Query Neighborhood Hits	101	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

CCND1_HUMAN
θ value	4.03905 (rank : 53)	NC score	0.020510 (rank : 63)
Query Neighborhood Hits	101	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P24385, Q6LEF0	Gene names	CCND1, BCL1, PRAD1
Domain Architecture
Description	G1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene).

CF152_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.009498 (rank : 90)
Query Neighborhood Hits	101	Target Neighborhood Hits	704	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

DDX10_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.006449 (rank : 97)
Query Neighborhood Hits	101	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

HRX_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.023342 (rank : 53)
Query Neighborhood Hits	101	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

HXD10_MOUSE
θ value	4.03905 (rank : 57)	NC score	0.014022 (rank : 76)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	8
SwissProt Accessions	P28359, Q91WU9	Gene names	Hoxd10, Hox-4.5, Hoxd-10
Domain Architecture
Description	Homeobox protein Hox-D10 (Hox-4.5) (Hox-5.3).

LEO1_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.034098 (rank : 34)
Query Neighborhood Hits	101	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MARK3_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.000921 (rank : 104)
Query Neighborhood Hits	101	Target Neighborhood Hits	919	Shared Neighborhood Hits	8
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

MYPT1_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.007425 (rank : 95)
Query Neighborhood Hits	101	Target Neighborhood Hits	723	Shared Neighborhood Hits	13
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

RTP3_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.014178 (rank : 75)
Query Neighborhood Hits	101	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

TAOK2_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.005711 (rank : 99)
Query Neighborhood Hits	101	Target Neighborhood Hits	1172	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

TR240_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.023283 (rank : 55)
Query Neighborhood Hits	101	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

TTF1_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.045605 (rank : 25)
Query Neighborhood Hits	101	Target Neighborhood Hits	277	Shared Neighborhood Hits	14
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

CLGN_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.009952 (rank : 88)
Query Neighborhood Hits	101	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

DEK_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.032988 (rank : 37)
Query Neighborhood Hits	101	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

MLL2_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.018161 (rank : 66)
Query Neighborhood Hits	101	Target Neighborhood Hits	1788	Shared Neighborhood Hits	34
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYCD_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.013054 (rank : 79)
Query Neighborhood Hits	101	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

NP1L3_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.025000 (rank : 51)
Query Neighborhood Hits	101	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

PEX5_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.029681 (rank : 44)
Query Neighborhood Hits	101	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

SND1_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.018903 (rank : 65)
Query Neighborhood Hits	101	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q7KZF4, Q13122	Gene names	SND1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator) (EBNA2 coactivator p100).

SND1_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.018992 (rank : 64)
Query Neighborhood Hits	101	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q78PY7, Q3TT46, Q922L5, Q9R0S1	Gene names	Snd1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator).

ZBTB5_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.000974 (rank : 103)
Query Neighborhood Hits	101	Target Neighborhood Hits	811	Shared Neighborhood Hits	5
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

ACINU_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.022153 (rank : 59)
Query Neighborhood Hits	101	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF4_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.034743 (rank : 32)
Query Neighborhood Hits	101	Target Neighborhood Hits	611	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.031391 (rank : 40)
Query Neighborhood Hits	101	Target Neighborhood Hits	581	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AP3B1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.025631 (rank : 49)
Query Neighborhood Hits	101	Target Neighborhood Hits	283	Shared Neighborhood Hits	22
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

FMN2_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.013594 (rank : 78)
Query Neighborhood Hits	101	Target Neighborhood Hits	484	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

HN1L_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.014955 (rank : 72)
Query Neighborhood Hits	101	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PGH2	Gene names	D17Ertd441e
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

IF4B_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.022356 (rank : 57)
Query Neighborhood Hits	101	Target Neighborhood Hits	417	Shared Neighborhood Hits	24
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MBP_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.015670 (rank : 71)
Query Neighborhood Hits	101	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	P02686, Q15337, Q15338, Q15339, Q15340, Q6AI64, Q6FH37, Q6FI04, Q6PK23	Gene names	MBP
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein).

MCES_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.012830 (rank : 80)
Query Neighborhood Hits	101	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

NUAK1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.000256 (rank : 105)
Query Neighborhood Hits	101	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

RBBP5_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.010381 (rank : 86)
Query Neighborhood Hits	101	Target Neighborhood Hits	372	Shared Neighborhood Hits	8
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

TPR_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.006182 (rank : 98)
Query Neighborhood Hits	101	Target Neighborhood Hits	1921	Shared Neighborhood Hits	32
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

WAPL_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.030312 (rank : 42)
Query Neighborhood Hits	101	Target Neighborhood Hits	158	Shared Neighborhood Hits	16
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

ABP1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.010022 (rank : 87)
Query Neighborhood Hits	101	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZQ5, Q8R229, Q8VC36	Gene names	Abp1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase).

CT172_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.018004 (rank : 67)
Query Neighborhood Hits	101	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H410, Q5JW56, Q9H8P4	Gene names	C20orf172
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172.

DUS16_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.008026 (rank : 92)
Query Neighborhood Hits	101	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

ENAM_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.013633 (rank : 77)
Query Neighborhood Hits	101	Target Neighborhood Hits	229	Shared Neighborhood Hits	11
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

FMN2_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.010695 (rank : 85)
Query Neighborhood Hits	101	Target Neighborhood Hits	349	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

K1210_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.028645 (rank : 45)
Query Neighborhood Hits	101	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

MAP9_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.022318 (rank : 58)
Query Neighborhood Hits	101	Target Neighborhood Hits	529	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MBD2_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.007868 (rank : 93)
Query Neighborhood Hits	101	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

MYST4_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.012576 (rank : 81)
Query Neighborhood Hits	101	Target Neighborhood Hits	416	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PKNX1_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.008405 (rank : 91)
Query Neighborhood Hits	101	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	O70477	Gene names	Pknox1
Domain Architecture
Description	Homeobox protein PKNOX1 (PBX/knotted homeobox 1).

RAPH1_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.009498 (rank : 89)
Query Neighborhood Hits	101	Target Neighborhood Hits	593	Shared Neighborhood Hits	15
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

S29A1_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.007582 (rank : 94)
Query Neighborhood Hits	101	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q99808, Q9UJY2	Gene names	SLC29A1, ENT1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

SMC2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.005480 (rank : 100)
Query Neighborhood Hits	101	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SSDH_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.006781 (rank : 96)
Query Neighborhood Hits	101	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

STAM2_MOUSE
θ value	8.99809 (rank : 101)	NC score	0.004638 (rank : 101)
Query Neighborhood Hits	101	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

R51A1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.058525 (rank : 11)
Query Neighborhood Hits	101	Target Neighborhood Hits	164	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RBBP6_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.055312 (rank : 14)
Query Neighborhood Hits	101	Target Neighborhood Hits	1135	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

TGON2_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.056948 (rank : 13)
Query Neighborhood Hits	101	Target Neighborhood Hits	1037	Shared Neighborhood Hits	43
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.059262 (rank : 10)
Query Neighborhood Hits	101	Target Neighborhood Hits	828	Shared Neighborhood Hits	42
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

Hits sorted by NC score

TOP2B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	101
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_MOUSE
NC score	0.988656 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	101	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2A_MOUSE
NC score	0.972273 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	101	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2A_HUMAN
NC score	0.970087 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	101	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

IWS1_HUMAN
NC score	0.107928 (rank : 5)	θ value	0.000461057 (rank : 5)
Query Neighborhood Hits	101	Target Neighborhood Hits	1241	Shared Neighborhood Hits	50
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
NC score	0.098769 (rank : 6)	θ value	0.000602161 (rank : 6)
Query Neighborhood Hits	101	Target Neighborhood Hits	1258	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKA12_HUMAN
NC score	0.074969 (rank : 7)	θ value	0.00390308 (rank : 7)
Query Neighborhood Hits	101	Target Neighborhood Hits	825	Shared Neighborhood Hits	40
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ADDB_MOUSE
NC score	0.065832 (rank : 8)	θ value	0.00665767 (rank : 8)
Query Neighborhood Hits	101	Target Neighborhood Hits	574	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

TERF2_HUMAN
NC score	0.060612 (rank : 9)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	101	Target Neighborhood Hits	102	Shared Neighborhood Hits	8
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TXND2_MOUSE
NC score	0.059262 (rank : 10)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	101	Target Neighborhood Hits	828	Shared Neighborhood Hits	42
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

R51A1_MOUSE
NC score	0.058525 (rank : 11)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	101	Target Neighborhood Hits	164	Shared Neighborhood Hits	16
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

NOLC1_HUMAN
NC score	0.058012 (rank : 12)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	101	Target Neighborhood Hits	452	Shared Neighborhood Hits	34
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TGON2_HUMAN
NC score	0.056948 (rank : 13)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	101	Target Neighborhood Hits	1037	Shared Neighborhood Hits	43
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RBBP6_HUMAN
NC score	0.055312 (rank : 14)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	101	Target Neighborhood Hits	1135	Shared Neighborhood Hits	45
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

DSPP_MOUSE
NC score	0.054523 (rank : 15)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	101	Target Neighborhood Hits	491	Shared Neighborhood Hits	27
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PCNP_HUMAN
NC score	0.054260 (rank : 16)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	101	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WW12, Q6AI44, Q96CU3, Q9NS81	Gene names	PCNP
Domain Architecture	No domain graphic available
Description	PEST proteolytic signal-containing nuclear protein (PEST-containing nuclear protein) (PCNP).

TXND2_HUMAN
NC score	0.053676 (rank : 17)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	101	Target Neighborhood Hits	793	Shared Neighborhood Hits	40
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CF206_HUMAN
NC score	0.052844 (rank : 18)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	101	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1X1	Gene names	C6orf206, MRPS18AL1
Domain Architecture	No domain graphic available
Description	Protein C6orf206.

HTSF1_MOUSE
NC score	0.047483 (rank : 19)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	101	Target Neighborhood Hits	425	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BGC0, Q1WWK0, Q9CT41, Q9DAU3	Gene names	Htatsf1
Domain Architecture	No domain graphic available
Description	HIV Tat-specific factor 1 homolog.

FA21C_HUMAN
NC score	0.046740 (rank : 20)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	101	Target Neighborhood Hits	194	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

PCNP_MOUSE
NC score	0.046574 (rank : 21)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	101	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P8I4	Gene names	Pcnp
Domain Architecture	No domain graphic available
Description	PEST proteolytic signal-containing nuclear protein (PEST-containing nuclear protein) (PCNP).

MBB1A_HUMAN
NC score	0.046558 (rank : 22)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	101	Target Neighborhood Hits	665	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

DSPP_HUMAN
NC score	0.045920 (rank : 23)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	101	Target Neighborhood Hits	645	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NPAS4_HUMAN
NC score	0.045839 (rank : 24)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	101	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

TTF1_MOUSE
NC score	0.045605 (rank : 25)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	101	Target Neighborhood Hits	277	Shared Neighborhood Hits	14
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

RRBP1_HUMAN
NC score	0.042716 (rank : 26)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	101	Target Neighborhood Hits	1306	Shared Neighborhood Hits	31
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

AP3B2_HUMAN
NC score	0.039194 (rank : 27)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	101	Target Neighborhood Hits	246	Shared Neighborhood Hits	20
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

NPAS4_MOUSE
NC score	0.038837 (rank : 28)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	101	Target Neighborhood Hits	245	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

AF9_HUMAN
NC score	0.037254 (rank : 29)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	101	Target Neighborhood Hits	202	Shared Neighborhood Hits	17
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

MEPE_HUMAN
NC score	0.036680 (rank : 30)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	101	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NQ76	Gene names	MEPE
Domain Architecture
Description	Matrix extracellular phosphoglycoprotein precursor (Osteoblast/osteocyte factor 45) (OF45).

TFAM_HUMAN
NC score	0.036274 (rank : 31)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	101	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q00059	Gene names	TFAM, TCF6L2
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6-like 2).

AFF4_HUMAN
NC score	0.034743 (rank : 32)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	101	Target Neighborhood Hits	611	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

PARG_HUMAN
NC score	0.034730 (rank : 33)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	101	Target Neighborhood Hits	97	Shared Neighborhood Hits	14
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

LEO1_HUMAN
NC score	0.034098 (rank : 34)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	101	Target Neighborhood Hits	958	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

CJ012_HUMAN
NC score	0.033449 (rank : 35)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	101	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

AHTF1_HUMAN
NC score	0.033291 (rank : 36)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	101	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WYP5, Q7Z4E3, Q8IZA4, Q96EH9, Q9Y4Q6	Gene names	AHCTF1, ELYS, TMBS62
Domain Architecture	No domain graphic available
Description	AT-hook-containing transcription factor 1 (Embryonic large molecule derived from yolk sac).

DEK_HUMAN
NC score	0.032988 (rank : 37)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	101	Target Neighborhood Hits	199	Shared Neighborhood Hits	18
SwissProt Accessions	P35659, Q5TGV4, Q5TGV5	Gene names	DEK
Domain Architecture	No domain graphic available
Description	Protein DEK.

PHF2_MOUSE
NC score	0.032821 (rank : 38)	θ value	0.0193708 (rank : 9)
Query Neighborhood Hits	101	Target Neighborhood Hits	241	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ZN638_MOUSE
NC score	0.031959 (rank : 39)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	101	Target Neighborhood Hits	318	Shared Neighborhood Hits	12
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

AFF4_MOUSE
NC score	0.031391 (rank : 40)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	101	Target Neighborhood Hits	581	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

MPP8_HUMAN
NC score	0.031078 (rank : 41)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	101	Target Neighborhood Hits	948	Shared Neighborhood Hits	30
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

WAPL_MOUSE
NC score	0.030312 (rank : 42)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	101	Target Neighborhood Hits	158	Shared Neighborhood Hits	16
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

VPS72_HUMAN
NC score	0.030245 (rank : 43)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	101	Target Neighborhood Hits	274	Shared Neighborhood Hits	15
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

PEX5_HUMAN
NC score	0.029681 (rank : 44)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	101	Target Neighborhood Hits	92	Shared Neighborhood Hits	7
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

K1210_HUMAN
NC score	0.028645 (rank : 45)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	101	Target Neighborhood Hits	219	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

SET1A_HUMAN
NC score	0.028257 (rank : 46)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	101	Target Neighborhood Hits	690	Shared Neighborhood Hits	24
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

H10_HUMAN
NC score	0.026765 (rank : 47)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	101	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	P07305	Gene names	H1F0, H1FV
Domain Architecture
Description	Histone H1.0 (H1(0)) (Histone H1').

CCND1_MOUSE
NC score	0.025690 (rank : 48)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	101	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	P25322	Gene names	Ccnd1, Cyl-1
Domain Architecture
Description	G1/S-specific cyclin-D1.

AP3B1_HUMAN
NC score	0.025631 (rank : 49)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	101	Target Neighborhood Hits	283	Shared Neighborhood Hits	22
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

F10A1_HUMAN
NC score	0.025129 (rank : 50)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	101	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

NP1L3_MOUSE
NC score	0.025000 (rank : 51)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	101	Target Neighborhood Hits	233	Shared Neighborhood Hits	19
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

AFF2_HUMAN
NC score	0.024727 (rank : 52)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	101	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

HRX_HUMAN
NC score	0.023342 (rank : 53)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	101	Target Neighborhood Hits	825	Shared Neighborhood Hits	31
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CDA7L_MOUSE
NC score	0.023333 (rank : 54)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	101	Target Neighborhood Hits	42	Shared Neighborhood Hits	9
SwissProt Accessions	Q922M5	Gene names	Cdca7l
Domain Architecture	No domain graphic available
Description	Cell division cycle-associated 7-like protein (Transcription factor RAM2).

TR240_HUMAN
NC score	0.023283 (rank : 55)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	101	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHV7, O60334	Gene names	THRAP1, ARC250, KIAA0593, TRAP240
Domain Architecture
Description	Thyroid hormone receptor-associated protein complex 240 kDa component (Trap240) (Thyroid hormone receptor-associated protein 1) (Vitamin D3 receptor-interacting protein complex component DRIP250) (DRIP 250) (Activator-recruited cofactor 250 kDa component) (ARC250).

RGS3_HUMAN
NC score	0.023235 (rank : 56)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	101	Target Neighborhood Hits	1375	Shared Neighborhood Hits	22
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

IF4B_HUMAN
NC score	0.022356 (rank : 57)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	101	Target Neighborhood Hits	417	Shared Neighborhood Hits	24
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MAP9_MOUSE
NC score	0.022318 (rank : 58)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	101	Target Neighborhood Hits	529	Shared Neighborhood Hits	28
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

ACINU_HUMAN
NC score	0.022153 (rank : 59)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	101	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

SDPR_MOUSE
NC score	0.022083 (rank : 60)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	101	Target Neighborhood Hits	485	Shared Neighborhood Hits	17
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

RRBP1_MOUSE
NC score	0.021521 (rank : 61)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	101	Target Neighborhood Hits	1650	Shared Neighborhood Hits	34
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

FA8_HUMAN
NC score	0.020983 (rank : 62)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	101	Target Neighborhood Hits	112	Shared Neighborhood Hits	7
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

CCND1_HUMAN
NC score	0.020510 (rank : 63)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	101	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P24385, Q6LEF0	Gene names	CCND1, BCL1, PRAD1
Domain Architecture
Description	G1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene).

SND1_MOUSE
NC score	0.018992 (rank : 64)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	101	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q78PY7, Q3TT46, Q922L5, Q9R0S1	Gene names	Snd1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator).

SND1_HUMAN
NC score	0.018903 (rank : 65)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	101	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q7KZF4, Q13122	Gene names	SND1
Domain Architecture	No domain graphic available
Description	Staphylococcal nuclease domain-containing protein 1 (p100 co- activator) (100 kDa coactivator) (EBNA2 coactivator p100).

MLL2_HUMAN
NC score	0.018161 (rank : 66)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	101	Target Neighborhood Hits	1788	Shared Neighborhood Hits	34
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CT172_HUMAN
NC score	0.018004 (rank : 67)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	101	Target Neighborhood Hits	47	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H410, Q5JW56, Q9H8P4	Gene names	C20orf172
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf172.

TUFT1_HUMAN
NC score	0.017865 (rank : 68)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	101	Target Neighborhood Hits	686	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CRBB3_MOUSE
NC score	0.017390 (rank : 69)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	101	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JJU9	Gene names	Crybb3
Domain Architecture
Description	Beta crystallin B3 (Beta-B3-crystallin).

MCM5_HUMAN
NC score	0.016747 (rank : 70)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	101	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P33992, O60785, Q14578, Q9BTJ4, Q9BWL8	Gene names	MCM5, CDC46
Domain Architecture
Description	DNA replication licensing factor MCM5 (CDC46 homolog) (P1-CDC46).

MBP_HUMAN
NC score	0.015670 (rank : 71)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	101	Target Neighborhood Hits	33	Shared Neighborhood Hits	6
SwissProt Accessions	P02686, Q15337, Q15338, Q15339, Q15340, Q6AI64, Q6FH37, Q6FI04, Q6PK23	Gene names	MBP
Domain Architecture
Description	Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane encephalitogenic protein).

HN1L_MOUSE
NC score	0.014955 (rank : 72)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	101	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PGH2	Gene names	D17Ertd441e
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

SAMN1_MOUSE
NC score	0.014726 (rank : 73)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	101	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	P57725, Q8C6S2	Gene names	Samsn1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1).

HXD10_HUMAN
NC score	0.014723 (rank : 74)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	7
SwissProt Accessions	P28358	Gene names	HOXD10, HOX4D
Domain Architecture
Description	Homeobox protein Hox-D10 (Hox-4D) (Hox-4E).

RTP3_MOUSE
NC score	0.014178 (rank : 75)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	101	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

HXD10_MOUSE
NC score	0.014022 (rank : 76)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	101	Target Neighborhood Hits	392	Shared Neighborhood Hits	8
SwissProt Accessions	P28359, Q91WU9	Gene names	Hoxd10, Hox-4.5, Hoxd-10
Domain Architecture
Description	Homeobox protein Hox-D10 (Hox-4.5) (Hox-5.3).

ENAM_MOUSE
NC score	0.013633 (rank : 77)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	101	Target Neighborhood Hits	229	Shared Neighborhood Hits	11
SwissProt Accessions	O55196	Gene names	Enam
Domain Architecture	No domain graphic available
Description	Enamelin precursor.

FMN2_HUMAN
NC score	0.013594 (rank : 78)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	101	Target Neighborhood Hits	484	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

MYCD_HUMAN
NC score	0.013054 (rank : 79)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	101	Target Neighborhood Hits	167	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MCES_HUMAN
NC score	0.012830 (rank : 80)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	101	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	O43148, O94996, Q9UIJ9	Gene names	RNMT, KIAA0398
Domain Architecture	No domain graphic available
Description	mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (mRNA (guanine- N(7)-)-methyltransferase) (RG7MT1) (mRNA cap methyltransferase) (hcm1p) (hCMT1) (hMet).

MYST4_MOUSE
NC score	0.012576 (rank : 81)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	101	Target Neighborhood Hits	416	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

TAOK2_MOUSE
NC score	0.011861 (rank : 82)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	101	Target Neighborhood Hits	1373	Shared Neighborhood Hits	19
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

RECQ5_HUMAN
NC score	0.011606 (rank : 83)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	101	Target Neighborhood Hits	390	Shared Neighborhood Hits	7
SwissProt Accessions	O94762, Q9P1W7, Q9UNC8	Gene names	RECQL5, RECQ5
Domain Architecture
Description	ATP-dependent DNA helicase Q5 (EC 3.6.1.-) (RecQ protein-like 5) (RecQ5).

AHI1_HUMAN
NC score	0.010917 (rank : 84)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	101	Target Neighborhood Hits	537	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

FMN2_MOUSE
NC score	0.010695 (rank : 85)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	101	Target Neighborhood Hits	349	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

RBBP5_HUMAN
NC score	0.010381 (rank : 86)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	101	Target Neighborhood Hits	372	Shared Neighborhood Hits	8
SwissProt Accessions	Q15291	Gene names	RBBP5, RBQ3
Domain Architecture
Description	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3).

ABP1_MOUSE
NC score	0.010022 (rank : 87)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	101	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q8JZQ5, Q8R229, Q8VC36	Gene names	Abp1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase).

CLGN_HUMAN
NC score	0.009952 (rank : 88)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	101	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	O14967	Gene names	CLGN
Domain Architecture
Description	Calmegin precursor.

RAPH1_HUMAN
NC score	0.009498 (rank : 89)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	101	Target Neighborhood Hits	593	Shared Neighborhood Hits	15
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

CF152_HUMAN
NC score	0.009498 (rank : 90)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	101	Target Neighborhood Hits	704	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VQ0, Q9BWX7	Gene names	C6orf152
Domain Architecture	No domain graphic available
Description	Protein C6orf152.

PKNX1_MOUSE
NC score	0.008405 (rank : 91)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	101	Target Neighborhood Hits	103	Shared Neighborhood Hits	5
SwissProt Accessions	O70477	Gene names	Pknox1
Domain Architecture
Description	Homeobox protein PKNOX1 (PBX/knotted homeobox 1).

DUS16_HUMAN
NC score	0.008026 (rank : 92)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	101	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

MBD2_HUMAN
NC score	0.007868 (rank : 93)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	101	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UBB5, O95242, Q9UIS8	Gene names	MBD2
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2) (Demethylase) (DMTase).

S29A1_HUMAN
NC score	0.007582 (rank : 94)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	101	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q99808, Q9UJY2	Gene names	SLC29A1, ENT1
Domain Architecture
Description	Equilibrative nucleoside transporter 1 (Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter) (Equilibrative NBMPR-sensitive nucleoside transporter) (Nucleoside transporter, es-type) (Solute carrier family 29 member 1).

MYPT1_HUMAN
NC score	0.007425 (rank : 95)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	101	Target Neighborhood Hits	723	Shared Neighborhood Hits	13
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

SSDH_HUMAN
NC score	0.006781 (rank : 96)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	101	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	P51649	Gene names	ALDH5A1, SSADH
Domain Architecture
Description	Succinate semialdehyde dehydrogenase, mitochondrial precursor (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase).

DDX10_HUMAN
NC score	0.006449 (rank : 97)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	101	Target Neighborhood Hits	210	Shared Neighborhood Hits	12
SwissProt Accessions	Q13206, Q5BJD8	Gene names	DDX10
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX10 (EC 3.6.1.-) (DEAD box protein 10).

TPR_HUMAN
NC score	0.006182 (rank : 98)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	101	Target Neighborhood Hits	1921	Shared Neighborhood Hits	32
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

TAOK2_HUMAN
NC score	0.005711 (rank : 99)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	101	Target Neighborhood Hits	1172	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

SMC2_HUMAN
NC score	0.005480 (rank : 100)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	101	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

STAM2_MOUSE
NC score	0.004638 (rank : 101)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	101	Target Neighborhood Hits	285	Shared Neighborhood Hits	5
SwissProt Accessions	O88811, Q8C8Y4	Gene names	Stam2, Hbp
Domain Architecture	No domain graphic available
Description	Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein).

LATS1_MOUSE
NC score	0.002604 (rank : 102)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	101	Target Neighborhood Hits	1027	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

ZBTB5_HUMAN
NC score	0.000974 (rank : 103)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	101	Target Neighborhood Hits	811	Shared Neighborhood Hits	5
SwissProt Accessions	O15062	Gene names	ZBTB5, KIAA0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5.

MARK3_MOUSE
NC score	0.000921 (rank : 104)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	101	Target Neighborhood Hits	919	Shared Neighborhood Hits	8
SwissProt Accessions	Q03141, Q3TM40, Q3V1U3, Q8C6G9, Q8R375, Q9JKE4	Gene names	Mark3, Emk2, Mpk10
Domain Architecture	No domain graphic available
Description	MAP/microtubule affinity-regulating kinase 3 (EC 2.7.11.1) (MPK-10) (ELKL motif kinase 2).

NUAK1_HUMAN
NC score	0.000256 (rank : 105)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	101	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).