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Network neighborhood for query Sequence : PEX5_HUMAN

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PEX5_HUMAN
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PEX5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

PEX5_MOUSE
θ value	0 (rank : 2)	NC score	0.994349 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

PEX5R_MOUSE
θ value	7.37397e-111 (rank : 3)	NC score	0.932094 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PEX5R_HUMAN
θ value	4.77967e-110 (rank : 4)	NC score	0.924539 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

OGT1_HUMAN
θ value	2.52405e-10 (rank : 5)	NC score	0.439872 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	143	Shared Neighborhood Hits	70
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

CDC27_HUMAN
θ value	1.53129e-07 (rank : 6)	NC score	0.392333 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	139	Shared Neighborhood Hits	61
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

BBS4_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.314332 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

K0372_HUMAN
θ value	0.00102713 (rank : 8)	NC score	0.324396 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	136	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

BBS4_MOUSE
θ value	0.00175202 (rank : 9)	NC score	0.314547 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

SGTA_MOUSE
θ value	0.00228821 (rank : 10)	NC score	0.243925 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BJU0, Q8BGA6, Q99L52	Gene names	Sgta, Sgt
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A.

CDC23_HUMAN
θ value	0.00509761 (rank : 11)	NC score	0.255954 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CDC23_MOUSE
θ value	0.00509761 (rank : 12)	NC score	0.255858 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

IFIT3_MOUSE
θ value	0.00509761 (rank : 13)	NC score	0.177045 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	Q64345, Q99L62	Gene names	Ifit3, Garg49, Ifi49
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (Glucocorticoid-attenuated response gene 49 protein) (GARG-49) (IRG2).

TF3C3_HUMAN
θ value	0.00509761 (rank : 14)	NC score	0.265987 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

SGTA_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.237398 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O43765, Q9BTZ9	Gene names	SGTA, SGT
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein) (UBP).

SGTB_HUMAN
θ value	0.0113563 (rank : 16)	NC score	0.227225 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q96EQ0	Gene names	SGTB, SGT2
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B (Small glutamine-rich protein with tetratricopeptide repeats 2).

SGTB_MOUSE
θ value	0.0148317 (rank : 17)	NC score	0.219831 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VD33	Gene names	Sgtb
Domain Architecture	No domain graphic available
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B.

STUB1_HUMAN
θ value	0.0148317 (rank : 18)	NC score	0.205236 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

STUB1_MOUSE
θ value	0.0148317 (rank : 19)	NC score	0.207472 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

TTC6_HUMAN
θ value	0.0193708 (rank : 20)	NC score	0.300098 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	54
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

DNJC7_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.173984 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

RBP2_MOUSE
θ value	0.0330416 (rank : 22)	NC score	0.087859 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

TTC13_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.274413 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

RBP2_HUMAN
θ value	0.0431538 (rank : 24)	NC score	0.089115 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

KLC3_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.147760 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P597, Q6GMU2, Q8NAL1, Q8WWJ9	Gene names	KLC3, KLC2, KLC2L
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3 (kinesin light chain 2) (KLC2-like).

IFT88_MOUSE
θ value	0.0736092 (rank : 26)	NC score	0.232339 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

IFIT1_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.131512 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q64282	Gene names	Ifit1, Garg16, Ifi56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (Glucocorticoid- attenuated response gene 16 protein) (GARG-16).

KLC3_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.143629 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	Q91W40, Q3TZ56	Gene names	Klc3
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3.

DNJC7_HUMAN
θ value	0.163984 (rank : 29)	NC score	0.167318 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	212	Shared Neighborhood Hits	48
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

RBP22_HUMAN
θ value	0.163984 (rank : 30)	NC score	0.104168 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RGPD8_HUMAN
θ value	0.163984 (rank : 31)	NC score	0.104405 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	19
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

TTC7A_MOUSE
θ value	0.163984 (rank : 32)	NC score	0.177739 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BGB2, Q80XT5	Gene names	Ttc7a, Ttc7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

KLC1_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.117315 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	471	Shared Neighborhood Hits	29
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

SPAG1_HUMAN
θ value	0.21417 (rank : 34)	NC score	0.160314 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	197	Shared Neighborhood Hits	47
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

SPAG1_MOUSE
θ value	0.21417 (rank : 35)	NC score	0.183927 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

KLC4_MOUSE
θ value	0.279714 (rank : 36)	NC score	0.110188 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	336	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

RBP26_HUMAN
θ value	0.279714 (rank : 37)	NC score	0.100701 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	146	Shared Neighborhood Hits	19
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

TRI35_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.013744 (rank : 121)
Query Neighborhood Hits	92	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

UTX_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.154294 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	161	Shared Neighborhood Hits	33
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

UTY_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.138330 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

UTY_MOUSE
θ value	0.47712 (rank : 41)	NC score	0.138485 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

CLCA_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.033658 (rank : 111)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

IFT88_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.199685 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	122	Shared Neighborhood Hits	51
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

KLC1_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.124341 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

F10A1_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.151453 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	312	Shared Neighborhood Hits	37
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

F10A1_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.166220 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q99L47, Q4FJT4	Gene names	St13, Fam10a1, Hip
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Protein ST13 homolog) (Protein FAM10A1).

F10A4_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.158404 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	249	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

F10A5_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.159439 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	277	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

KLC4_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.105636 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

NARGL_MOUSE
θ value	0.813845 (rank : 50)	NC score	0.079145 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

S3TC1_HUMAN
θ value	0.813845 (rank : 51)	NC score	0.057799 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

TOM70_HUMAN
θ value	0.813845 (rank : 52)	NC score	0.162846 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	127	Shared Neighborhood Hits	49
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
θ value	0.813845 (rank : 53)	NC score	0.159901 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TTC7A_HUMAN
θ value	0.813845 (rank : 54)	NC score	0.143480 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

CTR9_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.140336 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	383	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTR9_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.138717 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	427	Shared Neighborhood Hits	56
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

IF4B_MOUSE
θ value	1.06291 (rank : 57)	NC score	0.030232 (rank : 112)
Query Neighborhood Hits	92	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IFIT2_HUMAN
θ value	1.06291 (rank : 58)	NC score	0.114062 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P09913	Gene names	IFIT2, G10P2, IFI54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (ISG-54 K).

DREB_HUMAN
θ value	1.38821 (rank : 59)	NC score	0.021854 (rank : 117)
Query Neighborhood Hits	92	Target Neighborhood Hits	450	Shared Neighborhood Hits	5
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

IFIT3_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.160496 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

KLC2_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.108372 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

MAP1A_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.012529 (rank : 122)
Query Neighborhood Hits	92	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

TTC7B_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.123905 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

KLC2_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.103124 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	244	Shared Neighborhood Hits	25
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

NARGL_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.065524 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	222	Shared Neighborhood Hits	33
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

PPP5_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.083138 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P53041, Q16722	Gene names	PPP5C, PPP5
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT).

STIP1_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.177072 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	147	Shared Neighborhood Hits	56
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

MACF1_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.007250 (rank : 127)
Query Neighborhood Hits	92	Target Neighborhood Hits	1341	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	3.0926 (rank : 69)	NC score	0.008821 (rank : 126)
Query Neighborhood Hits	92	Target Neighborhood Hits	1321	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MYPN_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.006981 (rank : 128)
Query Neighborhood Hits	92	Target Neighborhood Hits	421	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

PPP5_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.081232 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	Q60676, O35299	Gene names	Ppp5c
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PPT).

HS74L_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.010957 (rank : 123)
Query Neighborhood Hits	92	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

TOP2A_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.029654 (rank : 114)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

CEP55_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.006430 (rank : 129)
Query Neighborhood Hits	92	Target Neighborhood Hits	693	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

ESPL1_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.015017 (rank : 119)
Query Neighborhood Hits	92	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

IFIT1_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.098748 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	56	Shared Neighborhood Hits	34
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

STIP1_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.173407 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	154	Shared Neighborhood Hits	56
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

TOP2A_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.029025 (rank : 116)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2B_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.029681 (rank : 113)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.029130 (rank : 115)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

ASPH_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.041020 (rank : 110)
Query Neighborhood Hits	92	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

DNJC3_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.087237 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	223	Shared Neighborhood Hits	42
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DNJC3_MOUSE
θ value	6.88961 (rank : 83)	NC score	0.087665 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	230	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

IF4B_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.021069 (rank : 118)
Query Neighborhood Hits	92	Target Neighborhood Hits	417	Shared Neighborhood Hits	5
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TTC17_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.065669 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	118	Shared Neighborhood Hits	20
SwissProt Accessions	Q96AE7	Gene names	TTC17
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 17 (TPR repeat protein 17).

TTC3_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.057649 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	664	Shared Neighborhood Hits	29
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

TTLL4_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.009076 (rank : 125)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

G45IP_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.014148 (rank : 120)
Query Neighborhood Hits	92	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

HS74L_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.009167 (rank : 124)
Query Neighborhood Hits	92	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

TRHY_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.004303 (rank : 130)
Query Neighborhood Hits	92	Target Neighborhood Hits	1385	Shared Neighborhood Hits	21
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TTC16_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.081814 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	417	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TTC28_HUMAN
θ value	8.99809 (rank : 92)	NC score	0.074492 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	271	Shared Neighborhood Hits	45
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

APC7_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.078665 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

APC7_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.078480 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	56	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

CDC16_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.077661 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q13042, Q96AE6, Q9Y564	Gene names	CDC16
Domain Architecture
Description	Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

CDC16_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.076155 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R349, Q9CYX9	Gene names	Cdc16
Domain Architecture
Description	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

DYXC1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.081960 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	261	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

DYXC1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.083772 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	172	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

FKBP5_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.053272 (rank : 106)
Query Neighborhood Hits	92	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q13451	Gene names	FKBP5, AIG6, FKBP51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6).

FKBP5_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.052816 (rank : 109)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

FKBP8_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.058585 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q14318	Gene names	FKBP8, FKBP38
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8).

FKBP8_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.071552 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	O35465, Q99L93	Gene names	Fkbp8, Fkbp38, Sam11
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8) (muFKBP38).

IFIT2_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.076105 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	Q64112, Q62385	Gene names	Ifit2, Garg39, Ifi54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (Glucocorticoid- attenuated response gene 39 protein) (GARG-39).

IFIT5_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.084838 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	44	Shared Neighborhood Hits	25
SwissProt Accessions	Q13325	Gene names	IFIT5, RI58
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein).

NPHP3_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.087964 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	304	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

NPHP3_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.081358 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	335	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

OM34_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.095900 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	Q15785, Q9NTZ3	Gene names	TOMM34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit) (hTom34).

OM34_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.102945 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CYG7, Q3THD0, Q9D059	Gene names	Tomm34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit).

PPID_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.052887 (rank : 108)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

RANG_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.060913 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

RANG_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.061527 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

SUGT1_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.065707 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2Z0, Q5JAK5, Q6VXY6	Gene names	SUGT1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog (Sgt1) (Putative 40-6-3 protein).

SUGT1_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.084741 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CX34, Q3UF88, Q9CRE7, Q9D8M6	Gene names	Sugt1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog.

TTC12_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.101828 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

TTC12_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.103969 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	98	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

TTC14_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.087862 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TTC16_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.117675 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TTC1_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.090526 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	417	Shared Neighborhood Hits	39
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TTC1_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.099165 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TTC28_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.070289 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	194	Shared Neighborhood Hits	44
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC4_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.065408 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	O95801, Q9H3I2	Gene names	TTC4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

TTC4_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.084731 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3H9	Gene names	Ttc4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

TTC8_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.084504 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAM2, Q86SY0, Q86TV9, Q86U26, Q8NDH9, Q96DG8	Gene names	TTC8, BBS8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein).

TTC8_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.085756 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VD72, Q9DCP7	Gene names	Ttc8, Bbs8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein homolog).

UN45A_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.055684 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

UN45A_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.066354 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	129	Shared Neighborhood Hits	34
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

UN45B_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.056802 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

UN45B_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.057937 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

WDTC1_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.053614 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	299	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

WDTC1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.052951 (rank : 107)
Query Neighborhood Hits	92	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

Hits sorted by NC score

PEX5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

PEX5_MOUSE
NC score	0.994349 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	71
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

PEX5R_MOUSE
NC score	0.932094 (rank : 3)	θ value	7.37397e-111 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PEX5R_HUMAN
NC score	0.924539 (rank : 4)	θ value	4.77967e-110 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

OGT1_HUMAN
NC score	0.439872 (rank : 5)	θ value	2.52405e-10 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	143	Shared Neighborhood Hits	70
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

CDC27_HUMAN
NC score	0.392333 (rank : 6)	θ value	1.53129e-07 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	139	Shared Neighborhood Hits	61
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

K0372_HUMAN
NC score	0.324396 (rank : 7)	θ value	0.00102713 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	136	Shared Neighborhood Hits	61
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

BBS4_MOUSE
NC score	0.314547 (rank : 8)	θ value	0.00175202 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	95	Shared Neighborhood Hits	54
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

BBS4_HUMAN
NC score	0.314332 (rank : 9)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	109	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

TTC6_HUMAN
NC score	0.300098 (rank : 10)	θ value	0.0193708 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	54
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

TTC13_HUMAN
NC score	0.274413 (rank : 11)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	117	Shared Neighborhood Hits	55
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

TF3C3_HUMAN
NC score	0.265987 (rank : 12)	θ value	0.00509761 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

CDC23_HUMAN
NC score	0.255954 (rank : 13)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CDC23_MOUSE
NC score	0.255858 (rank : 14)	θ value	0.00509761 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

SGTA_MOUSE
NC score	0.243925 (rank : 15)	θ value	0.00228821 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BJU0, Q8BGA6, Q99L52	Gene names	Sgta, Sgt
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A.

SGTA_HUMAN
NC score	0.237398 (rank : 16)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	O43765, Q9BTZ9	Gene names	SGTA, SGT
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein) (UBP).

IFT88_MOUSE
NC score	0.232339 (rank : 17)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

SGTB_HUMAN
NC score	0.227225 (rank : 18)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	96	Shared Neighborhood Hits	45
SwissProt Accessions	Q96EQ0	Gene names	SGTB, SGT2
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B (Small glutamine-rich protein with tetratricopeptide repeats 2).

SGTB_MOUSE
NC score	0.219831 (rank : 19)	θ value	0.0148317 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q8VD33	Gene names	Sgtb
Domain Architecture	No domain graphic available
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B.

STUB1_MOUSE
NC score	0.207472 (rank : 20)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

STUB1_HUMAN
NC score	0.205236 (rank : 21)	θ value	0.0148317 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	99	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

IFT88_HUMAN
NC score	0.199685 (rank : 22)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	122	Shared Neighborhood Hits	51
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

SPAG1_MOUSE
NC score	0.183927 (rank : 23)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	218	Shared Neighborhood Hits	51
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

TTC7A_MOUSE
NC score	0.177739 (rank : 24)	θ value	0.163984 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BGB2, Q80XT5	Gene names	Ttc7a, Ttc7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

STIP1_HUMAN
NC score	0.177072 (rank : 25)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	147	Shared Neighborhood Hits	56
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

IFIT3_MOUSE
NC score	0.177045 (rank : 26)	θ value	0.00509761 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	Q64345, Q99L62	Gene names	Ifit3, Garg49, Ifi49
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (Glucocorticoid-attenuated response gene 49 protein) (GARG-49) (IRG2).

DNJC7_MOUSE
NC score	0.173984 (rank : 27)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	211	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

STIP1_MOUSE
NC score	0.173407 (rank : 28)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	154	Shared Neighborhood Hits	56
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

DNJC7_HUMAN
NC score	0.167318 (rank : 29)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	212	Shared Neighborhood Hits	48
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

F10A1_MOUSE
NC score	0.166220 (rank : 30)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	117	Shared Neighborhood Hits	35
SwissProt Accessions	Q99L47, Q4FJT4	Gene names	St13, Fam10a1, Hip
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Protein ST13 homolog) (Protein FAM10A1).

TOM70_HUMAN
NC score	0.162846 (rank : 31)	θ value	0.813845 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	127	Shared Neighborhood Hits	49
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

IFIT3_HUMAN
NC score	0.160496 (rank : 32)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	83	Shared Neighborhood Hits	43
SwissProt Accessions	O14879, Q99634, Q9BSK7	Gene names	IFIT3, IFI60, IFIT4
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) (IFIT-4) (Interferon-induced 60 kDa protein) (IFI-60K) (ISG-60) (CIG49) (Retinoic acid-induced gene G protein) (RIG-G).

SPAG1_HUMAN
NC score	0.160314 (rank : 33)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	197	Shared Neighborhood Hits	47
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

TOM70_MOUSE
NC score	0.159901 (rank : 34)	θ value	0.813845 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	46
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

F10A5_HUMAN
NC score	0.159439 (rank : 35)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	277	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

F10A4_HUMAN
NC score	0.158404 (rank : 36)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	249	Shared Neighborhood Hits	33
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

UTX_HUMAN
NC score	0.154294 (rank : 37)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	161	Shared Neighborhood Hits	33
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

F10A1_HUMAN
NC score	0.151453 (rank : 38)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	312	Shared Neighborhood Hits	37
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

KLC3_HUMAN
NC score	0.147760 (rank : 39)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P597, Q6GMU2, Q8NAL1, Q8WWJ9	Gene names	KLC3, KLC2, KLC2L
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3 (kinesin light chain 2) (KLC2-like).

KLC3_MOUSE
NC score	0.143629 (rank : 40)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	26
SwissProt Accessions	Q91W40, Q3TZ56	Gene names	Klc3
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3.

TTC7A_HUMAN
NC score	0.143480 (rank : 41)	θ value	0.813845 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	79	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

CTR9_HUMAN
NC score	0.140336 (rank : 42)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	383	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTR9_MOUSE
NC score	0.138717 (rank : 43)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	427	Shared Neighborhood Hits	56
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

UTY_MOUSE
NC score	0.138485 (rank : 44)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

UTY_HUMAN
NC score	0.138330 (rank : 45)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

IFIT1_MOUSE
NC score	0.131512 (rank : 46)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q64282	Gene names	Ifit1, Garg16, Ifi56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (Glucocorticoid- attenuated response gene 16 protein) (GARG-16).

KLC1_MOUSE
NC score	0.124341 (rank : 47)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	357	Shared Neighborhood Hits	29
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

TTC7B_HUMAN
NC score	0.123905 (rank : 48)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

TTC16_MOUSE
NC score	0.117675 (rank : 49)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	92	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

KLC1_HUMAN
NC score	0.117315 (rank : 50)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	471	Shared Neighborhood Hits	29
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

IFIT2_HUMAN
NC score	0.114062 (rank : 51)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	27
SwissProt Accessions	P09913	Gene names	IFIT2, G10P2, IFI54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (ISG-54 K).

KLC4_MOUSE
NC score	0.110188 (rank : 52)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	336	Shared Neighborhood Hits	27
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

KLC2_HUMAN
NC score	0.108372 (rank : 53)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	227	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

KLC4_HUMAN
NC score	0.105636 (rank : 54)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	327	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

RGPD8_HUMAN
NC score	0.104405 (rank : 55)	θ value	0.163984 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	19
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

RBP22_HUMAN
NC score	0.104168 (rank : 56)	θ value	0.163984 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

TTC12_MOUSE
NC score	0.103969 (rank : 57)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	92	Target Neighborhood Hits	98	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

KLC2_MOUSE
NC score	0.103124 (rank : 58)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	244	Shared Neighborhood Hits	25
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

OM34_MOUSE
NC score	0.102945 (rank : 59)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	39
SwissProt Accessions	Q9CYG7, Q3THD0, Q9D059	Gene names	Tomm34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit).

TTC12_HUMAN
NC score	0.101828 (rank : 60)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

RBP26_HUMAN
NC score	0.100701 (rank : 61)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	146	Shared Neighborhood Hits	19
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

TTC1_MOUSE
NC score	0.099165 (rank : 62)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	92	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

IFIT1_HUMAN
NC score	0.098748 (rank : 63)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	56	Shared Neighborhood Hits	34
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

OM34_HUMAN
NC score	0.095900 (rank : 64)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	37
SwissProt Accessions	Q15785, Q9NTZ3	Gene names	TOMM34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit) (hTom34).

TTC1_HUMAN
NC score	0.090526 (rank : 65)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	92	Target Neighborhood Hits	417	Shared Neighborhood Hits	39
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

RBP2_HUMAN
NC score	0.089115 (rank : 66)	θ value	0.0431538 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	249	Shared Neighborhood Hits	17
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

NPHP3_HUMAN
NC score	0.087964 (rank : 67)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	92	Target Neighborhood Hits	304	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

TTC14_HUMAN
NC score	0.087862 (rank : 68)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	92	Target Neighborhood Hits	274	Shared Neighborhood Hits	32
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

RBP2_MOUSE
NC score	0.087859 (rank : 69)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	232	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

DNJC3_MOUSE
NC score	0.087665 (rank : 70)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	230	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DNJC3_HUMAN
NC score	0.087237 (rank : 71)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	223	Shared Neighborhood Hits	42
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

TTC8_MOUSE
NC score	0.085756 (rank : 72)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	92	Target Neighborhood Hits	55	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VD72, Q9DCP7	Gene names	Ttc8, Bbs8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein homolog).

IFIT5_HUMAN
NC score	0.084838 (rank : 73)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	92	Target Neighborhood Hits	44	Shared Neighborhood Hits	25
SwissProt Accessions	Q13325	Gene names	IFIT5, RI58
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Retinoic acid- and interferon-inducible 58 kDa protein).

SUGT1_MOUSE
NC score	0.084741 (rank : 74)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	92	Target Neighborhood Hits	73	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CX34, Q3UF88, Q9CRE7, Q9D8M6	Gene names	Sugt1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog.

TTC4_MOUSE
NC score	0.084731 (rank : 75)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R3H9	Gene names	Ttc4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

TTC8_HUMAN
NC score	0.084504 (rank : 76)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	92	Target Neighborhood Hits	56	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAM2, Q86SY0, Q86TV9, Q86U26, Q8NDH9, Q96DG8	Gene names	TTC8, BBS8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein).

DYXC1_MOUSE
NC score	0.083772 (rank : 77)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	92	Target Neighborhood Hits	172	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

PPP5_HUMAN
NC score	0.083138 (rank : 78)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P53041, Q16722	Gene names	PPP5C, PPP5
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PP-T) (PPT).

DYXC1_HUMAN
NC score	0.081960 (rank : 79)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	92	Target Neighborhood Hits	261	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

TTC16_HUMAN
NC score	0.081814 (rank : 80)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	417	Shared Neighborhood Hits	45
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

NPHP3_MOUSE
NC score	0.081358 (rank : 81)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	92	Target Neighborhood Hits	335	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

PPP5_MOUSE
NC score	0.081232 (rank : 82)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	100	Shared Neighborhood Hits	37
SwissProt Accessions	Q60676, O35299	Gene names	Ppp5c
Domain Architecture
Description	Serine/threonine-protein phosphatase 5 (EC 3.1.3.16) (PP5) (Protein phosphatase T) (PPT).

NARGL_MOUSE
NC score	0.079145 (rank : 83)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	175	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

APC7_HUMAN
NC score	0.078665 (rank : 84)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	92	Target Neighborhood Hits	57	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

APC7_MOUSE
NC score	0.078480 (rank : 85)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	92	Target Neighborhood Hits	56	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

CDC16_HUMAN
NC score	0.077661 (rank : 86)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	92	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q13042, Q96AE6, Q9Y564	Gene names	CDC16
Domain Architecture
Description	Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

CDC16_MOUSE
NC score	0.076155 (rank : 87)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	92	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R349, Q9CYX9	Gene names	Cdc16
Domain Architecture
Description	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

IFIT2_MOUSE
NC score	0.076105 (rank : 88)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	Q64112, Q62385	Gene names	Ifit2, Garg39, Ifi54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (Glucocorticoid- attenuated response gene 39 protein) (GARG-39).

TTC28_HUMAN
NC score	0.074492 (rank : 89)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	271	Shared Neighborhood Hits	45
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

FKBP8_MOUSE
NC score	0.071552 (rank : 90)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	92	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	O35465, Q99L93	Gene names	Fkbp8, Fkbp38, Sam11
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8) (muFKBP38).

TTC28_MOUSE
NC score	0.070289 (rank : 91)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	92	Target Neighborhood Hits	194	Shared Neighborhood Hits	44
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

UN45A_MOUSE
NC score	0.066354 (rank : 92)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	92	Target Neighborhood Hits	129	Shared Neighborhood Hits	34
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

SUGT1_HUMAN
NC score	0.065707 (rank : 93)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	92	Target Neighborhood Hits	66	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2Z0, Q5JAK5, Q6VXY6	Gene names	SUGT1
Domain Architecture
Description	Suppressor of G2 allele of SKP1 homolog (Sgt1) (Putative 40-6-3 protein).

TTC17_HUMAN
NC score	0.065669 (rank : 94)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	118	Shared Neighborhood Hits	20
SwissProt Accessions	Q96AE7	Gene names	TTC17
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 17 (TPR repeat protein 17).

NARGL_HUMAN
NC score	0.065524 (rank : 95)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	222	Shared Neighborhood Hits	33
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

TTC4_HUMAN
NC score	0.065408 (rank : 96)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	92	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	O95801, Q9H3I2	Gene names	TTC4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

RANG_MOUSE
NC score	0.061527 (rank : 97)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	92	Target Neighborhood Hits	15	Shared Neighborhood Hits	5
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RANG_HUMAN
NC score	0.060913 (rank : 98)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	92	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

FKBP8_HUMAN
NC score	0.058585 (rank : 99)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	92	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q14318	Gene names	FKBP8, FKBP38
Domain Architecture
Description	38 kDa FK506-binding protein homolog (FKBPR38) (FK506-binding protein 8).

UN45B_MOUSE
NC score	0.057937 (rank : 100)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

S3TC1_HUMAN
NC score	0.057799 (rank : 101)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

TTC3_HUMAN
NC score	0.057649 (rank : 102)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	664	Shared Neighborhood Hits	29
SwissProt Accessions	P53804, O60767, P78476, P78477	Gene names	TTC3, TPRD
Domain Architecture
Description	Tetratricopeptide repeat protein 3 (TPR repeat protein 3) (TPR repeat protein D).

UN45B_HUMAN
NC score	0.056802 (rank : 103)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

UN45A_HUMAN
NC score	0.055684 (rank : 104)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	92	Target Neighborhood Hits	122	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

WDTC1_HUMAN
NC score	0.053614 (rank : 105)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	92	Target Neighborhood Hits	299	Shared Neighborhood Hits	26
SwissProt Accessions	Q8N5D0, Q9NV87, Q9UPW4	Gene names	WDTC1, KIAA1037
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

FKBP5_HUMAN
NC score	0.053272 (rank : 106)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	92	Target Neighborhood Hits	107	Shared Neighborhood Hits	34
SwissProt Accessions	Q13451	Gene names	FKBP5, AIG6, FKBP51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51) (54 kDa progesterone receptor-associated immunophilin) (FKBP54) (P54) (FF1 antigen) (HSP90-binding immunophilin) (Androgen-regulated protein 6).

WDTC1_MOUSE
NC score	0.052951 (rank : 107)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	92	Target Neighborhood Hits	298	Shared Neighborhood Hits	25
SwissProt Accessions	Q80ZK9	Gene names	Wdtc1
Domain Architecture
Description	WD and tetratricopeptide repeats protein 1.

PPID_HUMAN
NC score	0.052887 (rank : 108)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	30
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

FKBP5_MOUSE
NC score	0.052816 (rank : 109)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	92	Target Neighborhood Hits	97	Shared Neighborhood Hits	37
SwissProt Accessions	Q64378	Gene names	Fkbp5, Fkbp51
Domain Architecture
Description	FK506-binding protein 5 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (51 kDa FK506-binding protein) (FKBP- 51).

ASPH_HUMAN
NC score	0.041020 (rank : 110)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CLCA_HUMAN
NC score	0.033658 (rank : 111)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	90	Shared Neighborhood Hits	5
SwissProt Accessions	P09496	Gene names	CLTA
Domain Architecture
Description	Clathrin light chain A (Lca).

IF4B_MOUSE
NC score	0.030232 (rank : 112)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TOP2B_HUMAN
NC score	0.029681 (rank : 113)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2A_HUMAN
NC score	0.029654 (rank : 114)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	135	Shared Neighborhood Hits	5
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TOP2B_MOUSE
NC score	0.029130 (rank : 115)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2A_MOUSE
NC score	0.029025 (rank : 116)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	101	Shared Neighborhood Hits	5
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

DREB_HUMAN
NC score	0.021854 (rank : 117)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	450	Shared Neighborhood Hits	5
SwissProt Accessions	Q16643	Gene names	DBN1
Domain Architecture
Description	Drebrin (Developmentally-regulated brain protein).

IF4B_HUMAN
NC score	0.021069 (rank : 118)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	417	Shared Neighborhood Hits	5
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

ESPL1_MOUSE
NC score	0.015017 (rank : 119)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P60330	Gene names	Espl1, Esp1, Kiaa0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

G45IP_HUMAN
NC score	0.014148 (rank : 120)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TAE8, Q8IVM3, Q8TE51, Q969P9, Q9BSM6	Gene names	GADD45GIP1, PLINP1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1 (CR6-interacting factor 1) (CRIF1) (CKII beta-associating protein) (Papillomavirus L2-interacting nuclear protein 1) (PLINP-1).

TRI35_HUMAN
NC score	0.013744 (rank : 121)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	382	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

MAP1A_HUMAN
NC score	0.012529 (rank : 122)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

HS74L_MOUSE
NC score	0.010957 (rank : 123)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	P48722, P97854, Q8BQD0, Q8CC45, Q91X29	Gene names	Hspa4l, Apg1, Hsp4l, Osp94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

HS74L_HUMAN
NC score	0.009167 (rank : 124)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

TTLL4_MOUSE
NC score	0.009076 (rank : 125)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q80UG8, Q5U4C4	Gene names	Ttll4, Kiaa0173
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 4.

MACF4_HUMAN
NC score	0.008821 (rank : 126)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	1321	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.007250 (rank : 127)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	1341	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MYPN_MOUSE
NC score	0.006981 (rank : 128)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	421	Shared Neighborhood Hits	2
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

CEP55_MOUSE
NC score	0.006430 (rank : 129)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	693	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

TRHY_HUMAN
NC score	0.004303 (rank : 130)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	1385	Shared Neighborhood Hits	21
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.