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Network neighborhood for query Sequence : TTC28_HUMAN

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TTC28_HUMAN
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TTC28_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	271	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC28_MOUSE
θ value	0 (rank : 2)	NC score	0.962779 (rank : 2)
Query Neighborhood Hits	271	Target Neighborhood Hits	194	Shared Neighborhood Hits	111
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

GPSM2_HUMAN
θ value	9.83387e-39 (rank : 3)	NC score	0.677530 (rank : 3)
Query Neighborhood Hits	271	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

GPSM2_MOUSE
θ value	4.13158e-37 (rank : 4)	NC score	0.675008 (rank : 4)
Query Neighborhood Hits	271	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

GPSM1_MOUSE
θ value	2.50655e-34 (rank : 5)	NC score	0.668859 (rank : 5)
Query Neighborhood Hits	271	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	Q6IR34, Q61366, Q8BUK4, Q8BX78, Q8R0R9	Gene names	Gpsm1, Ags3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

GPSM1_HUMAN
θ value	4.72714e-33 (rank : 6)	NC score	0.665209 (rank : 6)
Query Neighborhood Hits	271	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q86YR5, Q86SR5, Q969T1, Q9UFS8	Gene names	GPSM1, AGS3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

RAPSN_HUMAN
θ value	3.89403e-11 (rank : 7)	NC score	0.415182 (rank : 7)
Query Neighborhood Hits	271	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
θ value	1.9326e-10 (rank : 8)	NC score	0.410012 (rank : 8)
Query Neighborhood Hits	271	Target Neighborhood Hits	92	Shared Neighborhood Hits	20
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

OGT1_HUMAN
θ value	6.21693e-09 (rank : 9)	NC score	0.378740 (rank : 9)
Query Neighborhood Hits	271	Target Neighborhood Hits	143	Shared Neighborhood Hits	59
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

S3TC2_MOUSE
θ value	8.11959e-09 (rank : 10)	NC score	0.308791 (rank : 10)
Query Neighborhood Hits	271	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

S3TC2_HUMAN
θ value	7.59969e-07 (rank : 11)	NC score	0.294556 (rank : 11)
Query Neighborhood Hits	271	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TF17, Q9H8I5	Gene names	SH3TC2, KIAA1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

TTC8_HUMAN
θ value	6.43352e-06 (rank : 12)	NC score	0.274058 (rank : 14)
Query Neighborhood Hits	271	Target Neighborhood Hits	56	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TAM2, Q86SY0, Q86TV9, Q86U26, Q8NDH9, Q96DG8	Gene names	TTC8, BBS8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein).

UTY_HUMAN
θ value	0.000121331 (rank : 13)	NC score	0.208194 (rank : 23)
Query Neighborhood Hits	271	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

KLC1_MOUSE
θ value	0.000158464 (rank : 14)	NC score	0.198811 (rank : 31)
Query Neighborhood Hits	271	Target Neighborhood Hits	357	Shared Neighborhood Hits	39
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

TTC8_MOUSE
θ value	0.00020696 (rank : 15)	NC score	0.253445 (rank : 18)
Query Neighborhood Hits	271	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VD72, Q9DCP7	Gene names	Ttc8, Bbs8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein homolog).

KLC1_HUMAN
θ value	0.00035302 (rank : 16)	NC score	0.193101 (rank : 35)
Query Neighborhood Hits	271	Target Neighborhood Hits	471	Shared Neighborhood Hits	41
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

UTY_MOUSE
θ value	0.00035302 (rank : 17)	NC score	0.209071 (rank : 22)
Query Neighborhood Hits	271	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

IFT88_HUMAN
θ value	0.000461057 (rank : 18)	NC score	0.279717 (rank : 13)
Query Neighborhood Hits	271	Target Neighborhood Hits	122	Shared Neighborhood Hits	50
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

UTX_HUMAN
θ value	0.000461057 (rank : 19)	NC score	0.206541 (rank : 25)
Query Neighborhood Hits	271	Target Neighborhood Hits	161	Shared Neighborhood Hits	43
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

IFT88_MOUSE
θ value	0.000602161 (rank : 20)	NC score	0.283688 (rank : 12)
Query Neighborhood Hits	271	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

KLC4_MOUSE
θ value	0.000602161 (rank : 21)	NC score	0.204948 (rank : 26)
Query Neighborhood Hits	271	Target Neighborhood Hits	336	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

MINK1_MOUSE
θ value	0.000602161 (rank : 22)	NC score	0.015978 (rank : 221)
Query Neighborhood Hits	271	Target Neighborhood Hits	1451	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

S3TC1_HUMAN
θ value	0.000602161 (rank : 23)	NC score	0.271081 (rank : 15)
Query Neighborhood Hits	271	Target Neighborhood Hits	78	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

BBS4_MOUSE
θ value	0.00102713 (rank : 24)	NC score	0.258380 (rank : 17)
Query Neighborhood Hits	271	Target Neighborhood Hits	95	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

TTC13_HUMAN
θ value	0.00102713 (rank : 25)	NC score	0.266788 (rank : 16)
Query Neighborhood Hits	271	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

NACAM_MOUSE
θ value	0.00134147 (rank : 26)	NC score	0.089699 (rank : 63)
Query Neighborhood Hits	271	Target Neighborhood Hits	1866	Shared Neighborhood Hits	122
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NPHP3_HUMAN
θ value	0.00134147 (rank : 27)	NC score	0.215108 (rank : 21)
Query Neighborhood Hits	271	Target Neighborhood Hits	304	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

BBS4_HUMAN
θ value	0.00175202 (rank : 28)	NC score	0.237216 (rank : 20)
Query Neighborhood Hits	271	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

CDC27_HUMAN
θ value	0.00228821 (rank : 29)	NC score	0.244985 (rank : 19)
Query Neighborhood Hits	271	Target Neighborhood Hits	139	Shared Neighborhood Hits	50
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

KLC4_HUMAN
θ value	0.00228821 (rank : 30)	NC score	0.201170 (rank : 30)
Query Neighborhood Hits	271	Target Neighborhood Hits	327	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

RAI1_MOUSE
θ value	0.00390308 (rank : 31)	NC score	0.063679 (rank : 88)
Query Neighborhood Hits	271	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TTC12_MOUSE
θ value	0.00390308 (rank : 32)	NC score	0.166965 (rank : 42)
Query Neighborhood Hits	271	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

CDC16_MOUSE
θ value	0.00509761 (rank : 33)	NC score	0.206807 (rank : 24)
Query Neighborhood Hits	271	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R349, Q9CYX9	Gene names	Cdc16
Domain Architecture
Description	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

EGR1_MOUSE
θ value	0.00509761 (rank : 34)	NC score	0.014893 (rank : 227)
Query Neighborhood Hits	271	Target Neighborhood Hits	816	Shared Neighborhood Hits	24
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

GRIN1_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.106351 (rank : 60)
Query Neighborhood Hits	271	Target Neighborhood Hits	681	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

EGR1_HUMAN
θ value	0.00665767 (rank : 36)	NC score	0.014026 (rank : 232)
Query Neighborhood Hits	271	Target Neighborhood Hits	788	Shared Neighborhood Hits	20
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

NPHP3_MOUSE
θ value	0.00869519 (rank : 37)	NC score	0.201632 (rank : 28)
Query Neighborhood Hits	271	Target Neighborhood Hits	335	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

TOM70_MOUSE
θ value	0.00869519 (rank : 38)	NC score	0.159565 (rank : 46)
Query Neighborhood Hits	271	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_HUMAN
θ value	0.0148317 (rank : 39)	NC score	0.161560 (rank : 45)
Query Neighborhood Hits	271	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

WNK4_HUMAN
θ value	0.0148317 (rank : 40)	NC score	0.022487 (rank : 187)
Query Neighborhood Hits	271	Target Neighborhood Hits	1043	Shared Neighborhood Hits	48
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

CDC16_HUMAN
θ value	0.0252991 (rank : 41)	NC score	0.196545 (rank : 33)
Query Neighborhood Hits	271	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q13042, Q96AE6, Q9Y564	Gene names	CDC16
Domain Architecture
Description	Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

IFIT1_HUMAN
θ value	0.0252991 (rank : 42)	NC score	0.089476 (rank : 64)
Query Neighborhood Hits	271	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

MAST4_HUMAN
θ value	0.0252991 (rank : 43)	NC score	0.020726 (rank : 194)
Query Neighborhood Hits	271	Target Neighborhood Hits	1804	Shared Neighborhood Hits	94
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

STIP1_MOUSE
θ value	0.0252991 (rank : 44)	NC score	0.201485 (rank : 29)
Query Neighborhood Hits	271	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

KLC3_MOUSE
θ value	0.0330416 (rank : 45)	NC score	0.195637 (rank : 34)
Query Neighborhood Hits	271	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q91W40, Q3TZ56	Gene names	Klc3
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3.

NOTC1_MOUSE
θ value	0.0330416 (rank : 46)	NC score	0.015394 (rank : 223)
Query Neighborhood Hits	271	Target Neighborhood Hits	916	Shared Neighborhood Hits	19
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TTC19_HUMAN
θ value	0.0330416 (rank : 47)	NC score	0.165346 (rank : 43)
Query Neighborhood Hits	271	Target Neighborhood Hits	40	Shared Neighborhood Hits	20
SwissProt Accessions	Q6DKK2, Q7L3U8, Q9NXB2	Gene names	TTC19
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 19 (TPR repeat protein 19).

ZBTB3_HUMAN
θ value	0.0330416 (rank : 48)	NC score	0.016671 (rank : 218)
Query Neighborhood Hits	271	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

EVL_HUMAN
θ value	0.0431538 (rank : 49)	NC score	0.064806 (rank : 85)
Query Neighborhood Hits	271	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

K0372_HUMAN
θ value	0.0431538 (rank : 50)	NC score	0.189021 (rank : 36)
Query Neighborhood Hits	271	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

KLC2_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.186347 (rank : 38)
Query Neighborhood Hits	271	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

APBP2_HUMAN
θ value	0.0563607 (rank : 52)	NC score	0.156471 (rank : 49)
Query Neighborhood Hits	271	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q92624, O95095, Q8WVC9	Gene names	APPBP2, KIAA0228, PAT1
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2) (Protein interacting with APP tail 1).

APBP2_MOUSE
θ value	0.0563607 (rank : 53)	NC score	0.156473 (rank : 48)
Query Neighborhood Hits	271	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DAX9, Q80U61	Gene names	Appbp2, Kiaa0228
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2).

KLC2_MOUSE
θ value	0.0563607 (rank : 54)	NC score	0.183504 (rank : 39)
Query Neighborhood Hits	271	Target Neighborhood Hits	244	Shared Neighborhood Hits	39
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

EVL_MOUSE
θ value	0.0736092 (rank : 55)	NC score	0.058976 (rank : 96)
Query Neighborhood Hits	271	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SGTB_HUMAN
θ value	0.0736092 (rank : 56)	NC score	0.141852 (rank : 54)
Query Neighborhood Hits	271	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EQ0	Gene names	SGTB, SGT2
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B (Small glutamine-rich protein with tetratricopeptide repeats 2).

CN037_MOUSE
θ value	0.0961366 (rank : 57)	NC score	0.086596 (rank : 65)
Query Neighborhood Hits	271	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

DNJC7_MOUSE
θ value	0.0961366 (rank : 58)	NC score	0.117770 (rank : 59)
Query Neighborhood Hits	271	Target Neighborhood Hits	211	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

FANCG_HUMAN
θ value	0.0961366 (rank : 59)	NC score	0.082341 (rank : 70)
Query Neighborhood Hits	271	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	O15287	Gene names	FANCG, XRCC9
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein (Protein FACG) (DNA-repair protein XRCC9).

IF140_HUMAN
θ value	0.0961366 (rank : 60)	NC score	0.081298 (rank : 72)
Query Neighborhood Hits	271	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

SI1L2_MOUSE
θ value	0.0961366 (rank : 61)	NC score	0.027224 (rank : 171)
Query Neighborhood Hits	271	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

STIP1_HUMAN
θ value	0.0961366 (rank : 62)	NC score	0.202792 (rank : 27)
Query Neighborhood Hits	271	Target Neighborhood Hits	147	Shared Neighborhood Hits	59
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

CP250_MOUSE
θ value	0.125558 (rank : 63)	NC score	0.028602 (rank : 165)
Query Neighborhood Hits	271	Target Neighborhood Hits	1583	Shared Neighborhood Hits	55
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

AFF1_MOUSE
θ value	0.163984 (rank : 64)	NC score	0.054988 (rank : 102)
Query Neighborhood Hits	271	Target Neighborhood Hits	351	Shared Neighborhood Hits	43
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

CDC23_MOUSE
θ value	0.163984 (rank : 65)	NC score	0.162710 (rank : 44)
Query Neighborhood Hits	271	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

TARA_MOUSE
θ value	0.21417 (rank : 66)	NC score	0.050245 (rank : 120)
Query Neighborhood Hits	271	Target Neighborhood Hits	1133	Shared Neighborhood Hits	75
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ZEP1_HUMAN
θ value	0.21417 (rank : 67)	NC score	0.024195 (rank : 180)
Query Neighborhood Hits	271	Target Neighborhood Hits	1036	Shared Neighborhood Hits	52
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

MUC1_MOUSE
θ value	0.279714 (rank : 68)	NC score	0.069176 (rank : 80)
Query Neighborhood Hits	271	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NCOA6_HUMAN
θ value	0.279714 (rank : 69)	NC score	0.066998 (rank : 82)
Query Neighborhood Hits	271	Target Neighborhood Hits	1202	Shared Neighborhood Hits	99
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RPB1_HUMAN
θ value	0.279714 (rank : 70)	NC score	0.061146 (rank : 91)
Query Neighborhood Hits	271	Target Neighborhood Hits	362	Shared Neighborhood Hits	43
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	0.279714 (rank : 71)	NC score	0.061074 (rank : 93)
Query Neighborhood Hits	271	Target Neighborhood Hits	363	Shared Neighborhood Hits	42
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

BIG1_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.030145 (rank : 158)
Query Neighborhood Hits	271	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CBL_MOUSE
θ value	0.365318 (rank : 73)	NC score	0.037572 (rank : 147)
Query Neighborhood Hits	271	Target Neighborhood Hits	426	Shared Neighborhood Hits	33
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

DNJC7_HUMAN
θ value	0.365318 (rank : 74)	NC score	0.104826 (rank : 61)
Query Neighborhood Hits	271	Target Neighborhood Hits	212	Shared Neighborhood Hits	41
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

MUC13_MOUSE
θ value	0.365318 (rank : 75)	NC score	0.054658 (rank : 103)
Query Neighborhood Hits	271	Target Neighborhood Hits	447	Shared Neighborhood Hits	37
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SGTB_MOUSE
θ value	0.365318 (rank : 76)	NC score	0.127084 (rank : 57)
Query Neighborhood Hits	271	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VD33	Gene names	Sgtb
Domain Architecture	No domain graphic available
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B.

UBP31_HUMAN
θ value	0.365318 (rank : 77)	NC score	0.029173 (rank : 163)
Query Neighborhood Hits	271	Target Neighborhood Hits	293	Shared Neighborhood Hits	31
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

DCP1A_HUMAN
θ value	0.47712 (rank : 78)	NC score	0.061095 (rank : 92)
Query Neighborhood Hits	271	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

K1802_MOUSE
θ value	0.47712 (rank : 79)	NC score	0.047263 (rank : 127)
Query Neighborhood Hits	271	Target Neighborhood Hits	1596	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KLC3_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.175959 (rank : 40)
Query Neighborhood Hits	271	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q6P597, Q6GMU2, Q8NAL1, Q8WWJ9	Gene names	KLC3, KLC2, KLC2L
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3 (kinesin light chain 2) (KLC2-like).

PO6F2_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.023338 (rank : 183)
Query Neighborhood Hits	271	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SGIP1_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.054487 (rank : 104)
Query Neighborhood Hits	271	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SRRM2_MOUSE
θ value	0.47712 (rank : 83)	NC score	0.078054 (rank : 74)
Query Neighborhood Hits	271	Target Neighborhood Hits	1470	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ANK3_HUMAN
θ value	0.62314 (rank : 84)	NC score	0.017427 (rank : 213)
Query Neighborhood Hits	271	Target Neighborhood Hits	853	Shared Neighborhood Hits	55
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

DPOLZ_HUMAN
θ value	0.62314 (rank : 85)	NC score	0.027040 (rank : 173)
Query Neighborhood Hits	271	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

SEN34_MOUSE
θ value	0.62314 (rank : 86)	NC score	0.039194 (rank : 146)
Query Neighborhood Hits	271	Target Neighborhood Hits	158	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

TAU_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.042210 (rank : 139)
Query Neighborhood Hits	271	Target Neighborhood Hits	448	Shared Neighborhood Hits	38
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TBCD4_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.021130 (rank : 193)
Query Neighborhood Hits	271	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

WNK4_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.016956 (rank : 215)
Query Neighborhood Hits	271	Target Neighborhood Hits	961	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

BAP1_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.048127 (rank : 124)
Query Neighborhood Hits	271	Target Neighborhood Hits	118	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

BSN_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.050074 (rank : 121)
Query Neighborhood Hits	271	Target Neighborhood Hits	1537	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CCNB3_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.023755 (rank : 181)
Query Neighborhood Hits	271	Target Neighborhood Hits	368	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

K1802_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.040852 (rank : 143)
Query Neighborhood Hits	271	Target Neighborhood Hits	1378	Shared Neighborhood Hits	80
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

LAMC2_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.019969 (rank : 199)
Query Neighborhood Hits	271	Target Neighborhood Hits	715	Shared Neighborhood Hits	18
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

NOTC1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.012044 (rank : 244)
Query Neighborhood Hits	271	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NPBL_MOUSE
θ value	0.813845 (rank : 96)	NC score	0.046594 (rank : 129)
Query Neighborhood Hits	271	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PAPOA_HUMAN
θ value	0.813845 (rank : 97)	NC score	0.021494 (rank : 192)
Query Neighborhood Hits	271	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	P51003, Q86SX4, Q86TV0, Q8IYF5, Q9BVU2	Gene names	PAPOLA, PAP
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase alpha).

PDZD2_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.046828 (rank : 128)
Query Neighborhood Hits	271	Target Neighborhood Hits	772	Shared Neighborhood Hits	68
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

SGTA_MOUSE
θ value	0.813845 (rank : 99)	NC score	0.122670 (rank : 58)
Query Neighborhood Hits	271	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJU0, Q8BGA6, Q99L52	Gene names	Sgta, Sgt
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A.

TTC12_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.130061 (rank : 56)
Query Neighborhood Hits	271	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

ZN318_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.036341 (rank : 148)
Query Neighborhood Hits	271	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

ABI2_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.020637 (rank : 195)
Query Neighborhood Hits	271	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

ARI5B_HUMAN
θ value	1.06291 (rank : 103)	NC score	0.034853 (rank : 150)
Query Neighborhood Hits	271	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

CAF1A_MOUSE
θ value	1.06291 (rank : 104)	NC score	0.027157 (rank : 172)
Query Neighborhood Hits	271	Target Neighborhood Hits	736	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CBP_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.044662 (rank : 134)
Query Neighborhood Hits	271	Target Neighborhood Hits	941	Shared Neighborhood Hits	65
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	1.06291 (rank : 106)	NC score	0.045805 (rank : 130)
Query Neighborhood Hits	271	Target Neighborhood Hits	1051	Shared Neighborhood Hits	81
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CDC23_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.147587 (rank : 52)
Query Neighborhood Hits	271	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CENPC_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.033964 (rank : 153)
Query Neighborhood Hits	271	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CHD9_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.014981 (rank : 226)
Query Neighborhood Hits	271	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CNTP4_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.018684 (rank : 207)
Query Neighborhood Hits	271	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CP250_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.026813 (rank : 174)
Query Neighborhood Hits	271	Target Neighborhood Hits	1805	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

HXB5_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.010245 (rank : 260)
Query Neighborhood Hits	271	Target Neighborhood Hits	332	Shared Neighborhood Hits	11
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

NFAC1_MOUSE
θ value	1.06291 (rank : 113)	NC score	0.019211 (rank : 204)
Query Neighborhood Hits	271	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

SAMD4_HUMAN
θ value	1.06291 (rank : 114)	NC score	0.030411 (rank : 157)
Query Neighborhood Hits	271	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SGTA_HUMAN
θ value	1.06291 (rank : 115)	NC score	0.130717 (rank : 55)
Query Neighborhood Hits	271	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	O43765, Q9BTZ9	Gene names	SGTA, SGT
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein) (UBP).

SPT5H_HUMAN
θ value	1.06291 (rank : 116)	NC score	0.049288 (rank : 123)
Query Neighborhood Hits	271	Target Neighborhood Hits	436	Shared Neighborhood Hits	37
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

SPT5H_MOUSE
θ value	1.06291 (rank : 117)	NC score	0.050356 (rank : 118)
Query Neighborhood Hits	271	Target Neighborhood Hits	437	Shared Neighborhood Hits	39
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

VAX2_HUMAN
θ value	1.06291 (rank : 118)	NC score	0.011219 (rank : 254)
Query Neighborhood Hits	271	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIW0	Gene names	VAX2
Domain Architecture
Description	Ventral anterior homeobox 2.

FOXJ3_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.011707 (rank : 248)
Query Neighborhood Hits	271	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

HRH1_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.000430 (rank : 297)
Query Neighborhood Hits	271	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	P70174, Q91V75, Q91XN0, Q91XN1, Q91XN2, Q91XN3	Gene names	Hrh1, Bphs
Domain Architecture
Description	Histamine H1 receptor.

MAGD4_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.022587 (rank : 185)
Query Neighborhood Hits	271	Target Neighborhood Hits	338	Shared Neighborhood Hits	43
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

MYST3_HUMAN
θ value	1.38821 (rank : 122)	NC score	0.022869 (rank : 184)
Query Neighborhood Hits	271	Target Neighborhood Hits	772	Shared Neighborhood Hits	50
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

NFH_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.024945 (rank : 179)
Query Neighborhood Hits	271	Target Neighborhood Hits	1242	Shared Neighborhood Hits	75
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NIPBL_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.045193 (rank : 132)
Query Neighborhood Hits	271	Target Neighborhood Hits	1311	Shared Neighborhood Hits	80
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

YETS2_MOUSE
θ value	1.38821 (rank : 125)	NC score	0.035176 (rank : 149)
Query Neighborhood Hits	271	Target Neighborhood Hits	278	Shared Neighborhood Hits	31
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

APC_MOUSE
θ value	1.81305 (rank : 126)	NC score	0.050412 (rank : 117)
Query Neighborhood Hits	271	Target Neighborhood Hits	441	Shared Neighborhood Hits	36
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

BRDT_MOUSE
θ value	1.81305 (rank : 127)	NC score	0.019801 (rank : 201)
Query Neighborhood Hits	271	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

DDX20_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.008422 (rank : 272)
Query Neighborhood Hits	271	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

GLI1_MOUSE
θ value	1.81305 (rank : 129)	NC score	0.003062 (rank : 293)
Query Neighborhood Hits	271	Target Neighborhood Hits	785	Shared Neighborhood Hits	18
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

HXB5_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.009545 (rank : 263)
Query Neighborhood Hits	271	Target Neighborhood Hits	337	Shared Neighborhood Hits	11
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

IRS2_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.029464 (rank : 161)
Query Neighborhood Hits	271	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

MAGE1_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.042115 (rank : 140)
Query Neighborhood Hits	271	Target Neighborhood Hits	1389	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NASP_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.047599 (rank : 126)
Query Neighborhood Hits	271	Target Neighborhood Hits	709	Shared Neighborhood Hits	49
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NOLC1_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.055204 (rank : 101)
Query Neighborhood Hits	271	Target Neighborhood Hits	452	Shared Neighborhood Hits	45
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PO121_MOUSE
θ value	1.81305 (rank : 135)	NC score	0.040741 (rank : 144)
Query Neighborhood Hits	271	Target Neighborhood Hits	345	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PTC1_MOUSE
θ value	1.81305 (rank : 136)	NC score	0.016030 (rank : 220)
Query Neighborhood Hits	271	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

RGS3_MOUSE
θ value	1.81305 (rank : 137)	NC score	0.041657 (rank : 141)
Query Neighborhood Hits	271	Target Neighborhood Hits	1621	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SF3A1_HUMAN
θ value	1.81305 (rank : 138)	NC score	0.028571 (rank : 166)
Query Neighborhood Hits	271	Target Neighborhood Hits	199	Shared Neighborhood Hits	17
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SPEG_MOUSE
θ value	1.81305 (rank : 139)	NC score	0.012462 (rank : 242)
Query Neighborhood Hits	271	Target Neighborhood Hits	1959	Shared Neighborhood Hits	81
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SRBP1_MOUSE
θ value	1.81305 (rank : 140)	NC score	0.028161 (rank : 169)
Query Neighborhood Hits	271	Target Neighborhood Hits	384	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TBX18_MOUSE
θ value	1.81305 (rank : 141)	NC score	0.009474 (rank : 265)
Query Neighborhood Hits	271	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TITIN_HUMAN
θ value	1.81305 (rank : 142)	NC score	0.010005 (rank : 262)
Query Neighborhood Hits	271	Target Neighborhood Hits	2923	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZFP27_MOUSE
θ value	1.81305 (rank : 143)	NC score	-0.000308 (rank : 298)
Query Neighborhood Hits	271	Target Neighborhood Hits	764	Shared Neighborhood Hits	11
SwissProt Accessions	P10077, Q6PCZ6, Q8CED4	Gene names	Zfp27, Mkr4, Zfp-27
Domain Architecture	No domain graphic available
Description	Zinc finger protein 27 (Zfp-27) (Protein mKR4).

AIP_MOUSE
θ value	2.36792 (rank : 144)	NC score	0.050340 (rank : 119)
Query Neighborhood Hits	271	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	O08915	Gene names	Aip
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein).

ALO17_HUMAN
θ value	2.36792 (rank : 145)	NC score	0.030680 (rank : 156)
Query Neighborhood Hits	271	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

CJ012_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.053507 (rank : 106)
Query Neighborhood Hits	271	Target Neighborhood Hits	467	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

DAB2_MOUSE
θ value	2.36792 (rank : 147)	NC score	0.029705 (rank : 160)
Query Neighborhood Hits	271	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

EMIL2_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.015058 (rank : 225)
Query Neighborhood Hits	271	Target Neighborhood Hits	573	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

ICAL_MOUSE
θ value	2.36792 (rank : 149)	NC score	0.034410 (rank : 152)
Query Neighborhood Hits	271	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

NDC1_MOUSE
θ value	2.36792 (rank : 150)	NC score	0.025834 (rank : 178)
Query Neighborhood Hits	271	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VCB1	Gene names	Tmem48, Ndc1
Domain Architecture	No domain graphic available
Description	Nucleoporin NDC1 (Transmembrane protein 48).

RBM4B_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.008710 (rank : 270)
Query Neighborhood Hits	271	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQ04	Gene names	RBM4B, RBM30
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4B (RNA-binding motif protein 4B) (RNA-binding protein 30) (RNA-binding motif protein 30).

RUSC1_HUMAN
θ value	2.36792 (rank : 152)	NC score	0.019898 (rank : 200)
Query Neighborhood Hits	271	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

SRRM2_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.063137 (rank : 89)
Query Neighborhood Hits	271	Target Neighborhood Hits	1296	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TACC1_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.022135 (rank : 189)
Query Neighborhood Hits	271	Target Neighborhood Hits	597	Shared Neighborhood Hits	27
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TP53B_MOUSE
θ value	2.36792 (rank : 155)	NC score	0.051317 (rank : 114)
Query Neighborhood Hits	271	Target Neighborhood Hits	644	Shared Neighborhood Hits	64
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ABL1_MOUSE
θ value	3.0926 (rank : 156)	NC score	0.004737 (rank : 291)
Query Neighborhood Hits	271	Target Neighborhood Hits	1178	Shared Neighborhood Hits	40
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

AIP_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.050041 (rank : 122)
Query Neighborhood Hits	271	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O00170, Q99606	Gene names	AIP, XAP2
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2).

APC7_MOUSE
θ value	3.0926 (rank : 158)	NC score	0.086413 (rank : 66)
Query Neighborhood Hits	271	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

CTR9_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.157033 (rank : 47)
Query Neighborhood Hits	271	Target Neighborhood Hits	427	Shared Neighborhood Hits	79
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

GP1BA_HUMAN
θ value	3.0926 (rank : 160)	NC score	0.009247 (rank : 268)
Query Neighborhood Hits	271	Target Neighborhood Hits	407	Shared Neighborhood Hits	16
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

IF4B_MOUSE
θ value	3.0926 (rank : 161)	NC score	0.029461 (rank : 162)
Query Neighborhood Hits	271	Target Neighborhood Hits	368	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IL3B2_MOUSE
θ value	3.0926 (rank : 162)	NC score	0.020520 (rank : 197)
Query Neighborhood Hits	271	Target Neighborhood Hits	372	Shared Neighborhood Hits	23
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

LMO7_HUMAN
θ value	3.0926 (rank : 163)	NC score	0.022573 (rank : 186)
Query Neighborhood Hits	271	Target Neighborhood Hits	507	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

M3K3_MOUSE
θ value	3.0926 (rank : 164)	NC score	0.006394 (rank : 285)
Query Neighborhood Hits	271	Target Neighborhood Hits	876	Shared Neighborhood Hits	22
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

OPHN1_MOUSE
θ value	3.0926 (rank : 165)	NC score	0.013621 (rank : 235)
Query Neighborhood Hits	271	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

SGIP1_MOUSE
θ value	3.0926 (rank : 166)	NC score	0.045038 (rank : 133)
Query Neighborhood Hits	271	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

APC_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.054119 (rank : 105)
Query Neighborhood Hits	271	Target Neighborhood Hits	603	Shared Neighborhood Hits	56
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

ARNT_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.011686 (rank : 249)
Query Neighborhood Hits	271	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

CO039_HUMAN
θ value	4.03905 (rank : 169)	NC score	0.026620 (rank : 176)
Query Neighborhood Hits	271	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

CSKI2_HUMAN
θ value	4.03905 (rank : 170)	NC score	0.018279 (rank : 210)
Query Neighborhood Hits	271	Target Neighborhood Hits	747	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CUL7_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.021849 (rank : 190)
Query Neighborhood Hits	271	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DSG2_HUMAN
θ value	4.03905 (rank : 172)	NC score	0.002402 (rank : 296)
Query Neighborhood Hits	271	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q14126	Gene names	DSG2
Domain Architecture
Description	Desmoglein-2 precursor (HDGC).

DUET_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.005607 (rank : 288)
Query Neighborhood Hits	271	Target Neighborhood Hits	1220	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ETV5_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.011407 (rank : 251)
Query Neighborhood Hits	271	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

EXDL2_MOUSE
θ value	4.03905 (rank : 175)	NC score	0.028658 (rank : 164)
Query Neighborhood Hits	271	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

HES7_HUMAN
θ value	4.03905 (rank : 176)	NC score	0.018786 (rank : 206)
Query Neighborhood Hits	271	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

PA24D_HUMAN
θ value	4.03905 (rank : 177)	NC score	0.007599 (rank : 278)
Query Neighborhood Hits	271	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

PRG4_MOUSE
θ value	4.03905 (rank : 178)	NC score	0.051493 (rank : 113)
Query Neighborhood Hits	271	Target Neighborhood Hits	624	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SRRM1_MOUSE
θ value	4.03905 (rank : 179)	NC score	0.064555 (rank : 86)
Query Neighborhood Hits	271	Target Neighborhood Hits	966	Shared Neighborhood Hits	81
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TOP1M_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.016736 (rank : 216)
Query Neighborhood Hits	271	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q969P6	Gene names	TOP1MT
Domain Architecture
Description	DNA topoisomerase I, mitochondrial precursor (EC 5.99.1.2) (TOP1mt).

WDR22_MOUSE
θ value	4.03905 (rank : 181)	NC score	0.007761 (rank : 276)
Query Neighborhood Hits	271	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

5NT1B_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.020335 (rank : 198)
Query Neighborhood Hits	271	Target Neighborhood Hits	83	Shared Neighborhood Hits	14
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

ABCA1_MOUSE
θ value	5.27518 (rank : 183)	NC score	0.003454 (rank : 292)
Query Neighborhood Hits	271	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

AF10_HUMAN
θ value	5.27518 (rank : 184)	NC score	0.011033 (rank : 256)
Query Neighborhood Hits	271	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

ANC5_MOUSE
θ value	5.27518 (rank : 185)	NC score	0.027675 (rank : 170)
Query Neighborhood Hits	271	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

ARHGB_HUMAN
θ value	5.27518 (rank : 186)	NC score	0.013770 (rank : 234)
Query Neighborhood Hits	271	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

CABIN_HUMAN
θ value	5.27518 (rank : 187)	NC score	0.045659 (rank : 131)
Query Neighborhood Hits	271	Target Neighborhood Hits	490	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

CAC1E_HUMAN
θ value	5.27518 (rank : 188)	NC score	0.007638 (rank : 277)
Query Neighborhood Hits	271	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CK024_MOUSE
θ value	5.27518 (rank : 189)	NC score	0.043897 (rank : 135)
Query Neighborhood Hits	271	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

CNKR2_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.019482 (rank : 203)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	5.27518 (rank : 191)	NC score	0.019486 (rank : 202)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CSKI2_MOUSE
θ value	5.27518 (rank : 192)	NC score	0.018799 (rank : 205)
Query Neighborhood Hits	271	Target Neighborhood Hits	812	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CXCC1_MOUSE
θ value	5.27518 (rank : 193)	NC score	0.011745 (rank : 247)
Query Neighborhood Hits	271	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

ETV5_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.013119 (rank : 239)
Query Neighborhood Hits	271	Target Neighborhood Hits	328	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

FARP2_MOUSE
θ value	5.27518 (rank : 195)	NC score	0.006473 (rank : 283)
Query Neighborhood Hits	271	Target Neighborhood Hits	209	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

HCN1_MOUSE
θ value	5.27518 (rank : 196)	NC score	0.010514 (rank : 258)
Query Neighborhood Hits	271	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

JHD2C_HUMAN
θ value	5.27518 (rank : 197)	NC score	0.015800 (rank : 222)
Query Neighborhood Hits	271	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

LIPA3_HUMAN
θ value	5.27518 (rank : 198)	NC score	0.020556 (rank : 196)
Query Neighborhood Hits	271	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

LIPB2_MOUSE
θ value	5.27518 (rank : 199)	NC score	0.011657 (rank : 250)
Query Neighborhood Hits	271	Target Neighborhood Hits	570	Shared Neighborhood Hits	23
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

MAP2_HUMAN
θ value	5.27518 (rank : 200)	NC score	0.026695 (rank : 175)
Query Neighborhood Hits	271	Target Neighborhood Hits	348	Shared Neighborhood Hits	31
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

MARK2_HUMAN
θ value	5.27518 (rank : 201)	NC score	0.006669 (rank : 282)
Query Neighborhood Hits	271	Target Neighborhood Hits	1056	Shared Neighborhood Hits	36
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MEF2D_MOUSE
θ value	5.27518 (rank : 202)	NC score	0.014496 (rank : 231)
Query Neighborhood Hits	271	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MTG8R_HUMAN
θ value	5.27518 (rank : 203)	NC score	0.014872 (rank : 228)
Query Neighborhood Hits	271	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

NU214_HUMAN
θ value	5.27518 (rank : 204)	NC score	0.048083 (rank : 125)
Query Neighborhood Hits	271	Target Neighborhood Hits	657	Shared Neighborhood Hits	60
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PI5PA_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.028318 (rank : 167)
Query Neighborhood Hits	271	Target Neighborhood Hits	749	Shared Neighborhood Hits	57
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PPRB_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.033372 (rank : 154)
Query Neighborhood Hits	271	Target Neighborhood Hits	354	Shared Neighborhood Hits	39
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RAI14_MOUSE
θ value	5.27518 (rank : 207)	NC score	0.011965 (rank : 246)
Query Neighborhood Hits	271	Target Neighborhood Hits	1505	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RP1L1_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.031546 (rank : 155)
Query Neighborhood Hits	271	Target Neighborhood Hits	1072	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SYNP2_MOUSE
θ value	5.27518 (rank : 209)	NC score	0.018228 (rank : 211)
Query Neighborhood Hits	271	Target Neighborhood Hits	252	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

TEF_MOUSE
θ value	5.27518 (rank : 210)	NC score	0.011375 (rank : 252)
Query Neighborhood Hits	271	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

TTBK2_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.009305 (rank : 266)
Query Neighborhood Hits	271	Target Neighborhood Hits	822	Shared Neighborhood Hits	29
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

UBF1_MOUSE
θ value	5.27518 (rank : 212)	NC score	0.014662 (rank : 230)
Query Neighborhood Hits	271	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

VAX2_MOUSE
θ value	5.27518 (rank : 213)	NC score	0.008027 (rank : 274)
Query Neighborhood Hits	271	Target Neighborhood Hits	338	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTP9	Gene names	Vax2, Vex
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 2 (Ventral retina homeodomain protein).

ZC313_HUMAN
θ value	5.27518 (rank : 214)	NC score	0.028247 (rank : 168)
Query Neighborhood Hits	271	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

APC7_HUMAN
θ value	6.88961 (rank : 215)	NC score	0.078329 (rank : 73)
Query Neighborhood Hits	271	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

CD2L7_HUMAN
θ value	6.88961 (rank : 216)	NC score	0.006972 (rank : 281)
Query Neighborhood Hits	271	Target Neighborhood Hits	1275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

CTR9_HUMAN
θ value	6.88961 (rank : 217)	NC score	0.155294 (rank : 50)
Query Neighborhood Hits	271	Target Neighborhood Hits	383	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

DYNA_HUMAN
θ value	6.88961 (rank : 218)	NC score	0.014829 (rank : 229)
Query Neighborhood Hits	271	Target Neighborhood Hits	1194	Shared Neighborhood Hits	45
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

GMEB2_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.012720 (rank : 241)
Query Neighborhood Hits	271	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

IRX1_HUMAN
θ value	6.88961 (rank : 220)	NC score	0.006399 (rank : 284)
Query Neighborhood Hits	271	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

KI67_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.040906 (rank : 142)
Query Neighborhood Hits	271	Target Neighborhood Hits	581	Shared Neighborhood Hits	55
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LYPD3_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.017632 (rank : 212)
Query Neighborhood Hits	271	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	O95274, Q9UJ74	Gene names	LYPD3, C4.4A
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4).

MINT_MOUSE
θ value	6.88961 (rank : 223)	NC score	0.042353 (rank : 138)
Query Neighborhood Hits	271	Target Neighborhood Hits	1514	Shared Neighborhood Hits	95
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NARGL_MOUSE
θ value	6.88961 (rank : 224)	NC score	0.042979 (rank : 137)
Query Neighborhood Hits	271	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NCOA2_HUMAN
θ value	6.88961 (rank : 225)	NC score	0.018669 (rank : 208)
Query Neighborhood Hits	271	Target Neighborhood Hits	281	Shared Neighborhood Hits	34
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.016726 (rank : 217)
Query Neighborhood Hits	271	Target Neighborhood Hits	281	Shared Neighborhood Hits	25
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NEK4_MOUSE
θ value	6.88961 (rank : 227)	NC score	0.005006 (rank : 290)
Query Neighborhood Hits	271	Target Neighborhood Hits	899	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

PEX5_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.081941 (rank : 71)
Query Neighborhood Hits	271	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

PININ_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.018561 (rank : 209)
Query Neighborhood Hits	271	Target Neighborhood Hits	753	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RHG25_MOUSE
θ value	6.88961 (rank : 230)	NC score	0.013967 (rank : 233)
Query Neighborhood Hits	271	Target Neighborhood Hits	492	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SETBP_MOUSE
θ value	6.88961 (rank : 231)	NC score	0.034707 (rank : 151)
Query Neighborhood Hits	271	Target Neighborhood Hits	352	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

SETD2_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.015286 (rank : 224)
Query Neighborhood Hits	271	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SOX13_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.013203 (rank : 237)
Query Neighborhood Hits	271	Target Neighborhood Hits	464	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SPAG1_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.073077 (rank : 77)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

SPTA1_HUMAN
θ value	6.88961 (rank : 235)	NC score	0.010509 (rank : 259)
Query Neighborhood Hits	271	Target Neighborhood Hits	748	Shared Neighborhood Hits	24
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SPTA1_MOUSE
θ value	6.88961 (rank : 236)	NC score	0.011128 (rank : 255)
Query Neighborhood Hits	271	Target Neighborhood Hits	675	Shared Neighborhood Hits	20
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

SREC2_MOUSE
θ value	6.88961 (rank : 237)	NC score	0.011327 (rank : 253)
Query Neighborhood Hits	271	Target Neighborhood Hits	605	Shared Neighborhood Hits	29
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SSPO_MOUSE
θ value	6.88961 (rank : 238)	NC score	0.005554 (rank : 289)
Query Neighborhood Hits	271	Target Neighborhood Hits	800	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STUB1_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.083343 (rank : 68)
Query Neighborhood Hits	271	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

STUB1_MOUSE
θ value	6.88961 (rank : 240)	NC score	0.083325 (rank : 69)
Query Neighborhood Hits	271	Target Neighborhood Hits	97	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

AFF1_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.040577 (rank : 145)
Query Neighborhood Hits	271	Target Neighborhood Hits	506	Shared Neighborhood Hits	52
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

APOB_HUMAN
θ value	8.99809 (rank : 242)	NC score	0.011015 (rank : 257)
Query Neighborhood Hits	271	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

BSN_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.055456 (rank : 100)
Query Neighborhood Hits	271	Target Neighborhood Hits	2057	Shared Neighborhood Hits	124
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CAC1E_MOUSE
θ value	8.99809 (rank : 244)	NC score	0.007042 (rank : 280)
Query Neighborhood Hits	271	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CMTA2_MOUSE
θ value	8.99809 (rank : 245)	NC score	0.013123 (rank : 238)
Query Neighborhood Hits	271	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

DAB2_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.025908 (rank : 177)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	29
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

DVL1_MOUSE
θ value	8.99809 (rank : 247)	NC score	0.005822 (rank : 287)
Query Neighborhood Hits	271	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DYNA_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.012363 (rank : 243)
Query Neighborhood Hits	271	Target Neighborhood Hits	1084	Shared Neighborhood Hits	41
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EYA4_HUMAN
θ value	8.99809 (rank : 249)	NC score	0.011999 (rank : 245)
Query Neighborhood Hits	271	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

FOG1_MOUSE
θ value	8.99809 (rank : 250)	NC score	0.009261 (rank : 267)
Query Neighborhood Hits	271	Target Neighborhood Hits	1237	Shared Neighborhood Hits	53
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HCN1_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.008593 (rank : 271)
Query Neighborhood Hits	271	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

HCN2_MOUSE
θ value	8.99809 (rank : 252)	NC score	0.013318 (rank : 236)
Query Neighborhood Hits	271	Target Neighborhood Hits	278	Shared Neighborhood Hits	33
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

LAMP1_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.009493 (rank : 264)
Query Neighborhood Hits	271	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P11279	Gene names	LAMP1
Domain Architecture
Description	Lysosome-associated membrane glycoprotein 1 precursor (LAMP-1) (CD107a antigen).

MAK_HUMAN
θ value	8.99809 (rank : 254)	NC score	0.002501 (rank : 295)
Query Neighborhood Hits	271	Target Neighborhood Hits	857	Shared Neighborhood Hits	19
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

MRCKB_MOUSE
θ value	8.99809 (rank : 255)	NC score	0.006249 (rank : 286)
Query Neighborhood Hits	271	Target Neighborhood Hits	2180	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MUC2_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.030062 (rank : 159)
Query Neighborhood Hits	271	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

MY18A_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.008355 (rank : 273)
Query Neighborhood Hits	271	Target Neighborhood Hits	1929	Shared Neighborhood Hits	67
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYST3_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.017282 (rank : 214)
Query Neighborhood Hits	271	Target Neighborhood Hits	688	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NARGL_HUMAN
θ value	8.99809 (rank : 259)	NC score	0.043182 (rank : 136)
Query Neighborhood Hits	271	Target Neighborhood Hits	222	Shared Neighborhood Hits	33
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NHS_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.023590 (rank : 182)
Query Neighborhood Hits	271	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

NR1D1_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.002525 (rank : 294)
Query Neighborhood Hits	271	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

PEX5_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.074492 (rank : 75)
Query Neighborhood Hits	271	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

PTN23_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.016241 (rank : 219)
Query Neighborhood Hits	271	Target Neighborhood Hits	726	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PXK_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.013038 (rank : 240)
Query Neighborhood Hits	271	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

SM1L2_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.007527 (rank : 279)
Query Neighborhood Hits	271	Target Neighborhood Hits	1019	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SNAA_HUMAN
θ value	8.99809 (rank : 266)	NC score	0.008740 (rank : 269)
Query Neighborhood Hits	271	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P54920, Q96IK3, Q9BVJ3	Gene names	NAPA, SNAPA
Domain Architecture	No domain graphic available
Description	Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide- sensitive factor attachment protein, alpha).

TACC1_MOUSE
θ value	8.99809 (rank : 267)	NC score	0.022399 (rank : 188)
Query Neighborhood Hits	271	Target Neighborhood Hits	667	Shared Neighborhood Hits	34
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TF3C3_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.086020 (rank : 67)
Query Neighborhood Hits	271	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

TTBK2_MOUSE
θ value	8.99809 (rank : 269)	NC score	0.007970 (rank : 275)
Query Neighborhood Hits	271	Target Neighborhood Hits	811	Shared Neighborhood Hits	27
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

ZCH10_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.021633 (rank : 191)
Query Neighborhood Hits	271	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

ZO1_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.010048 (rank : 261)
Query Neighborhood Hits	271	Target Neighborhood Hits	474	Shared Neighborhood Hits	35
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

DYXC1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.050634 (rank : 116)
Query Neighborhood Hits	271	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

DYXC1_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.051583 (rank : 112)
Query Neighborhood Hits	271	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

F10A1_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.050979 (rank : 115)
Query Neighborhood Hits	271	Target Neighborhood Hits	117	Shared Neighborhood Hits	26
SwissProt Accessions	Q99L47, Q4FJT4	Gene names	St13, Fam10a1, Hip
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Protein ST13 homolog) (Protein FAM10A1).

F10A4_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.052998 (rank : 109)
Query Neighborhood Hits	271	Target Neighborhood Hits	249	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

F10A5_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.053504 (rank : 107)
Query Neighborhood Hits	271	Target Neighborhood Hits	277	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

GPSM3_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.170011 (rank : 41)
Query Neighborhood Hits	271	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4H4	Gene names	GPSM3, AGS4, C6orf9, G18
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 3 (Activator of G-protein signaling 4) (Protein G18) (G18.1b).

GPSM3_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.143637 (rank : 53)
Query Neighborhood Hits	271	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U1Z5, Q3U1M8, Q3UJZ5, Q8VDF9	Gene names	Gpsm3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 3.

IF3X_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.070424 (rank : 78)
Query Neighborhood Hits	271	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

MDC1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.051643 (rank : 111)
Query Neighborhood Hits	271	Target Neighborhood Hits	1446	Shared Neighborhood Hits	99
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NCOA6_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.053094 (rank : 108)
Query Neighborhood Hits	271	Target Neighborhood Hits	1076	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

OM34_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.059922 (rank : 94)
Query Neighborhood Hits	271	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	Q15785, Q9NTZ3	Gene names	TOMM34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit) (hTom34).

OM34_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.065973 (rank : 84)
Query Neighborhood Hits	271	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CYG7, Q3THD0, Q9D059	Gene names	Tomm34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit).

PCP2_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.198406 (rank : 32)
Query Neighborhood Hits	271	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IVA1, Q3KRG7	Gene names	PCP2
Domain Architecture
Description	Purkinje cell protein 2 homolog.

PCP2_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.188184 (rank : 37)
Query Neighborhood Hits	271	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P12660, P22941, Q3TV53	Gene names	Pcp2, Pcp-2
Domain Architecture
Description	Purkinje cell protein 2 (Protein PCD-5) (Purkinje cell-specific protein L7).

PEX5R_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.057396 (rank : 98)
Query Neighborhood Hits	271	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

PEX5R_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.059678 (rank : 95)
Query Neighborhood Hits	271	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

SPAG1_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.074376 (rank : 76)
Query Neighborhood Hits	271	Target Neighborhood Hits	218	Shared Neighborhood Hits	47
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

TARA_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.066881 (rank : 83)
Query Neighborhood Hits	271	Target Neighborhood Hits	1626	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TTC14_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.056976 (rank : 99)
Query Neighborhood Hits	271	Target Neighborhood Hits	274	Shared Neighborhood Hits	34
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TTC16_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.061457 (rank : 90)
Query Neighborhood Hits	271	Target Neighborhood Hits	417	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TTC16_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.057451 (rank : 97)
Query Neighborhood Hits	271	Target Neighborhood Hits	98	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TTC19_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.090066 (rank : 62)
Query Neighborhood Hits	271	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CC21	Gene names	Ttc19
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 19 (TPR repeat protein 19).

TTC1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.064201 (rank : 87)
Query Neighborhood Hits	271	Target Neighborhood Hits	417	Shared Neighborhood Hits	42
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TTC1_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.069696 (rank : 79)
Query Neighborhood Hits	271	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

TTC6_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.154271 (rank : 51)
Query Neighborhood Hits	271	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

UN45A_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.052541 (rank : 110)
Query Neighborhood Hits	271	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

UN45A_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.068670 (rank : 81)
Query Neighborhood Hits	271	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

Hits sorted by NC score

TTC28_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	271	Target Neighborhood Hits	271	Shared Neighborhood Hits	271
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC28_MOUSE
NC score	0.962779 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	271	Target Neighborhood Hits	194	Shared Neighborhood Hits	111
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

GPSM2_HUMAN
NC score	0.677530 (rank : 3)	θ value	9.83387e-39 (rank : 3)
Query Neighborhood Hits	271	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P81274, Q8N0Z5	Gene names	GPSM2, LGN
Domain Architecture
Description	G-protein signaling modulator 2 (Mosaic protein LGN).

GPSM2_MOUSE
NC score	0.675008 (rank : 4)	θ value	4.13158e-37 (rank : 4)
Query Neighborhood Hits	271	Target Neighborhood Hits	51	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VDU0, Q8BLX3	Gene names	Gpsm2, Lgn, Pins
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 2 (Pins homolog).

GPSM1_MOUSE
NC score	0.668859 (rank : 5)	θ value	2.50655e-34 (rank : 5)
Query Neighborhood Hits	271	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	Q6IR34, Q61366, Q8BUK4, Q8BX78, Q8R0R9	Gene names	Gpsm1, Ags3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

GPSM1_HUMAN
NC score	0.665209 (rank : 6)	θ value	4.72714e-33 (rank : 6)
Query Neighborhood Hits	271	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q86YR5, Q86SR5, Q969T1, Q9UFS8	Gene names	GPSM1, AGS3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 1 (Activator of G-protein signaling 3).

RAPSN_HUMAN
NC score	0.415182 (rank : 7)	θ value	3.89403e-11 (rank : 7)
Query Neighborhood Hits	271	Target Neighborhood Hits	84	Shared Neighborhood Hits	17
SwissProt Accessions	Q13702, Q9BTD9	Gene names	RAPSN
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RAPSN_MOUSE
NC score	0.410012 (rank : 8)	θ value	1.9326e-10 (rank : 8)
Query Neighborhood Hits	271	Target Neighborhood Hits	92	Shared Neighborhood Hits	20
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

OGT1_HUMAN
NC score	0.378740 (rank : 9)	θ value	6.21693e-09 (rank : 9)
Query Neighborhood Hits	271	Target Neighborhood Hits	143	Shared Neighborhood Hits	59
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

S3TC2_MOUSE
NC score	0.308791 (rank : 10)	θ value	8.11959e-09 (rank : 10)
Query Neighborhood Hits	271	Target Neighborhood Hits	83	Shared Neighborhood Hits	17
SwissProt Accessions	Q80VA5, Q8BWH2, Q8BXB8, Q8C0G6	Gene names	Sh3tc2, Kiaa1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

S3TC2_HUMAN
NC score	0.294556 (rank : 11)	θ value	7.59969e-07 (rank : 11)
Query Neighborhood Hits	271	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TF17, Q9H8I5	Gene names	SH3TC2, KIAA1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

IFT88_MOUSE
NC score	0.283688 (rank : 12)	θ value	0.000602161 (rank : 20)
Query Neighborhood Hits	271	Target Neighborhood Hits	124	Shared Neighborhood Hits	53
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

IFT88_HUMAN
NC score	0.279717 (rank : 13)	θ value	0.000461057 (rank : 18)
Query Neighborhood Hits	271	Target Neighborhood Hits	122	Shared Neighborhood Hits	50
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

TTC8_HUMAN
NC score	0.274058 (rank : 14)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	271	Target Neighborhood Hits	56	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TAM2, Q86SY0, Q86TV9, Q86U26, Q8NDH9, Q96DG8	Gene names	TTC8, BBS8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein).

S3TC1_HUMAN
NC score	0.271081 (rank : 15)	θ value	0.000602161 (rank : 23)
Query Neighborhood Hits	271	Target Neighborhood Hits	78	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TE82	Gene names	SH3TC1
Domain Architecture	No domain graphic available
Description	SH3 domain and tetratricopeptide repeats-containing protein 1.

TTC13_HUMAN
NC score	0.266788 (rank : 16)	θ value	0.00102713 (rank : 25)
Query Neighborhood Hits	271	Target Neighborhood Hits	117	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

BBS4_MOUSE
NC score	0.258380 (rank : 17)	θ value	0.00102713 (rank : 24)
Query Neighborhood Hits	271	Target Neighborhood Hits	95	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

TTC8_MOUSE
NC score	0.253445 (rank : 18)	θ value	0.00020696 (rank : 15)
Query Neighborhood Hits	271	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VD72, Q9DCP7	Gene names	Ttc8, Bbs8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein homolog).

CDC27_HUMAN
NC score	0.244985 (rank : 19)	θ value	0.00228821 (rank : 29)
Query Neighborhood Hits	271	Target Neighborhood Hits	139	Shared Neighborhood Hits	50
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

BBS4_HUMAN
NC score	0.237216 (rank : 20)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	271	Target Neighborhood Hits	109	Shared Neighborhood Hits	48
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

NPHP3_HUMAN
NC score	0.215108 (rank : 21)	θ value	0.00134147 (rank : 27)
Query Neighborhood Hits	271	Target Neighborhood Hits	304	Shared Neighborhood Hits	48
SwissProt Accessions	Q7Z494, Q5JPE3, Q5JPE6, Q68D99, Q6NVH3, Q7Z492, Q7Z493, Q8N9R2, Q8NCM5, Q96N70, Q96NK2	Gene names	NPHP3, KIAA2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

UTY_MOUSE
NC score	0.209071 (rank : 22)	θ value	0.00035302 (rank : 17)
Query Neighborhood Hits	271	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

UTY_HUMAN
NC score	0.208194 (rank : 23)	θ value	0.000121331 (rank : 13)
Query Neighborhood Hits	271	Target Neighborhood Hits	89	Shared Neighborhood Hits	37
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

CDC16_MOUSE
NC score	0.206807 (rank : 24)	θ value	0.00509761 (rank : 33)
Query Neighborhood Hits	271	Target Neighborhood Hits	58	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R349, Q9CYX9	Gene names	Cdc16
Domain Architecture
Description	Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

UTX_HUMAN
NC score	0.206541 (rank : 25)	θ value	0.000461057 (rank : 19)
Query Neighborhood Hits	271	Target Neighborhood Hits	161	Shared Neighborhood Hits	43
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

KLC4_MOUSE
NC score	0.204948 (rank : 26)	θ value	0.000602161 (rank : 21)
Query Neighborhood Hits	271	Target Neighborhood Hits	336	Shared Neighborhood Hits	44
SwissProt Accessions	Q9DBS5, Q3TCC5	Gene names	Klc4, Knsl8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

STIP1_HUMAN
NC score	0.202792 (rank : 27)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	271	Target Neighborhood Hits	147	Shared Neighborhood Hits	59
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

NPHP3_MOUSE
NC score	0.201632 (rank : 28)	θ value	0.00869519 (rank : 37)
Query Neighborhood Hits	271	Target Neighborhood Hits	335	Shared Neighborhood Hits	43
SwissProt Accessions	Q7TNH6, Q69Z39, Q8C798, Q8C7Z3, Q9D6D1	Gene names	Nphp3, Kiaa2000
Domain Architecture	No domain graphic available
Description	Nephrocystin-3.

STIP1_MOUSE
NC score	0.201485 (rank : 29)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	271	Target Neighborhood Hits	154	Shared Neighborhood Hits	57
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

KLC4_HUMAN
NC score	0.201170 (rank : 30)	θ value	0.00228821 (rank : 30)
Query Neighborhood Hits	271	Target Neighborhood Hits	327	Shared Neighborhood Hits	41
SwissProt Accessions	Q9NSK0	Gene names	KLC4, KNSL8
Domain Architecture
Description	Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8).

KLC1_MOUSE
NC score	0.198811 (rank : 31)	θ value	0.000158464 (rank : 14)
Query Neighborhood Hits	271	Target Neighborhood Hits	357	Shared Neighborhood Hits	39
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

PCP2_HUMAN
NC score	0.198406 (rank : 32)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	271	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IVA1, Q3KRG7	Gene names	PCP2
Domain Architecture
Description	Purkinje cell protein 2 homolog.

CDC16_HUMAN
NC score	0.196545 (rank : 33)	θ value	0.0252991 (rank : 41)
Query Neighborhood Hits	271	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q13042, Q96AE6, Q9Y564	Gene names	CDC16
Domain Architecture
Description	Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6).

KLC3_MOUSE
NC score	0.195637 (rank : 34)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	271	Target Neighborhood Hits	135	Shared Neighborhood Hits	38
SwissProt Accessions	Q91W40, Q3TZ56	Gene names	Klc3
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3.

KLC1_HUMAN
NC score	0.193101 (rank : 35)	θ value	0.00035302 (rank : 16)
Query Neighborhood Hits	271	Target Neighborhood Hits	471	Shared Neighborhood Hits	41
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

K0372_HUMAN
NC score	0.189021 (rank : 36)	θ value	0.0431538 (rank : 50)
Query Neighborhood Hits	271	Target Neighborhood Hits	136	Shared Neighborhood Hits	53
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

PCP2_MOUSE
NC score	0.188184 (rank : 37)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	271	Target Neighborhood Hits	20	Shared Neighborhood Hits	5
SwissProt Accessions	P12660, P22941, Q3TV53	Gene names	Pcp2, Pcp-2
Domain Architecture
Description	Purkinje cell protein 2 (Protein PCD-5) (Purkinje cell-specific protein L7).

KLC2_HUMAN
NC score	0.186347 (rank : 38)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	271	Target Neighborhood Hits	227	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0B6, Q9H9C8, Q9HA20	Gene names	KLC2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

KLC2_MOUSE
NC score	0.183504 (rank : 39)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	271	Target Neighborhood Hits	244	Shared Neighborhood Hits	39
SwissProt Accessions	O88448	Gene names	Klc2
Domain Architecture
Description	Kinesin light chain 2 (KLC 2).

KLC3_HUMAN
NC score	0.175959 (rank : 40)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	271	Target Neighborhood Hits	137	Shared Neighborhood Hits	37
SwissProt Accessions	Q6P597, Q6GMU2, Q8NAL1, Q8WWJ9	Gene names	KLC3, KLC2, KLC2L
Domain Architecture	No domain graphic available
Description	Kinesin light chain 3 (kinesin light chain 2) (KLC2-like).

GPSM3_HUMAN
NC score	0.170011 (rank : 41)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	271	Target Neighborhood Hits	10	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y4H4	Gene names	GPSM3, AGS4, C6orf9, G18
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 3 (Activator of G-protein signaling 4) (Protein G18) (G18.1b).

TTC12_MOUSE
NC score	0.166965 (rank : 42)	θ value	0.00390308 (rank : 32)
Query Neighborhood Hits	271	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BW49	Gene names	Ttc12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

TTC19_HUMAN
NC score	0.165346 (rank : 43)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	271	Target Neighborhood Hits	40	Shared Neighborhood Hits	20
SwissProt Accessions	Q6DKK2, Q7L3U8, Q9NXB2	Gene names	TTC19
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 19 (TPR repeat protein 19).

CDC23_MOUSE
NC score	0.162710 (rank : 44)	θ value	0.163984 (rank : 65)
Query Neighborhood Hits	271	Target Neighborhood Hits	65	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

TOM70_HUMAN
NC score	0.161560 (rank : 45)	θ value	0.0148317 (rank : 39)
Query Neighborhood Hits	271	Target Neighborhood Hits	127	Shared Neighborhood Hits	41
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
NC score	0.159565 (rank : 46)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	271	Target Neighborhood Hits	102	Shared Neighborhood Hits	37
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

CTR9_MOUSE
NC score	0.157033 (rank : 47)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	271	Target Neighborhood Hits	427	Shared Neighborhood Hits	79
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

APBP2_MOUSE
NC score	0.156473 (rank : 48)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	271	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9DAX9, Q80U61	Gene names	Appbp2, Kiaa0228
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2).

APBP2_HUMAN
NC score	0.156471 (rank : 49)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	271	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q92624, O95095, Q8WVC9	Gene names	APPBP2, KIAA0228, PAT1
Domain Architecture	No domain graphic available
Description	Amyloid protein-binding protein 2 (Amyloid beta precursor protein- binding protein 2) (APP-BP2) (Protein interacting with APP tail 1).

CTR9_HUMAN
NC score	0.155294 (rank : 50)	θ value	6.88961 (rank : 217)
Query Neighborhood Hits	271	Target Neighborhood Hits	383	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

TTC6_HUMAN
NC score	0.154271 (rank : 51)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	271	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

CDC23_HUMAN
NC score	0.147587 (rank : 52)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	271	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

GPSM3_MOUSE
NC score	0.143637 (rank : 53)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	271	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q3U1Z5, Q3U1M8, Q3UJZ5, Q8VDF9	Gene names	Gpsm3
Domain Architecture	No domain graphic available
Description	G-protein signaling modulator 3.

SGTB_HUMAN
NC score	0.141852 (rank : 54)	θ value	0.0736092 (rank : 56)
Query Neighborhood Hits	271	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	Q96EQ0	Gene names	SGTB, SGT2
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B (Small glutamine-rich protein with tetratricopeptide repeats 2).

SGTA_HUMAN
NC score	0.130717 (rank : 55)	θ value	1.06291 (rank : 115)
Query Neighborhood Hits	271	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	O43765, Q9BTZ9	Gene names	SGTA, SGT
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A (Vpu-binding protein) (UBP).

TTC12_HUMAN
NC score	0.130061 (rank : 56)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	271	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H892, Q8N5H9, Q9NWY3	Gene names	TTC12
Domain Architecture
Description	Tetratricopeptide repeat protein 12 (TPR repeat protein 12).

SGTB_MOUSE
NC score	0.127084 (rank : 57)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	271	Target Neighborhood Hits	90	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VD33	Gene names	Sgtb
Domain Architecture	No domain graphic available
Description	Small glutamine-rich tetratricopeptide repeat-containing protein B.

SGTA_MOUSE
NC score	0.122670 (rank : 58)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	271	Target Neighborhood Hits	112	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BJU0, Q8BGA6, Q99L52	Gene names	Sgta, Sgt
Domain Architecture
Description	Small glutamine-rich tetratricopeptide repeat-containing protein A.

DNJC7_MOUSE
NC score	0.117770 (rank : 59)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	271	Target Neighborhood Hits	211	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYI3, Q3TKR1, Q8BPG3, Q8CIL2, Q9CT29, Q9D026	Gene names	Dnajc7, Ttc2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2) (MDj11).

GRIN1_HUMAN
NC score	0.106351 (rank : 60)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	271	Target Neighborhood Hits	681	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DNJC7_HUMAN
NC score	0.104826 (rank : 61)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	271	Target Neighborhood Hits	212	Shared Neighborhood Hits	41
SwissProt Accessions	Q99615	Gene names	DNAJC7, TPR2, TTC2
Domain Architecture
Description	DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2).

TTC19_MOUSE
NC score	0.090066 (rank : 62)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	271	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CC21	Gene names	Ttc19
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 19 (TPR repeat protein 19).

NACAM_MOUSE
NC score	0.089699 (rank : 63)	θ value	0.00134147 (rank : 26)
Query Neighborhood Hits	271	Target Neighborhood Hits	1866	Shared Neighborhood Hits	122
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

IFIT1_HUMAN
NC score	0.089476 (rank : 64)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	271	Target Neighborhood Hits	56	Shared Neighborhood Hits	28
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

CN037_MOUSE
NC score	0.086596 (rank : 65)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	271	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BT18, Q8BFQ7, Q8R1Q5, Q9D6C5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf37 homolog precursor.

APC7_MOUSE
NC score	0.086413 (rank : 66)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	271	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

TF3C3_HUMAN
NC score	0.086020 (rank : 67)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	271	Target Neighborhood Hits	90	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

STUB1_HUMAN
NC score	0.083343 (rank : 68)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	271	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNE7, O60526, Q969U2, Q9HBT1	Gene names	STUB1, CHIP
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP) (CLL- associated antigen KW-8) (Antigen NY-CO-7).

STUB1_MOUSE
NC score	0.083325 (rank : 69)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	271	Target Neighborhood Hits	97	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WUD1, Q9DCJ0	Gene names	Stub1, Chip
Domain Architecture	No domain graphic available
Description	STIP1 homology and U box-containing protein 1 (EC 6.3.2.-) (STIP1 homology and U-box-containing protein 1) (Carboxy terminus of Hsp70- interacting protein) (E3 ubiquitin protein ligase CHIP).

FANCG_HUMAN
NC score	0.082341 (rank : 70)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	271	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	O15287	Gene names	FANCG, XRCC9
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein (Protein FACG) (DNA-repair protein XRCC9).

PEX5_MOUSE
NC score	0.081941 (rank : 71)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	271	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

IF140_HUMAN
NC score	0.081298 (rank : 72)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	271	Target Neighborhood Hits	111	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RY7, O60332	Gene names	IFT140, KIAA0590, WDTC2
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 140 homolog (WD and tetratricopeptide repeats protein 2).

APC7_HUMAN
NC score	0.078329 (rank : 73)	θ value	6.88961 (rank : 215)
Query Neighborhood Hits	271	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

SRRM2_MOUSE
NC score	0.078054 (rank : 74)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	271	Target Neighborhood Hits	1470	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PEX5_HUMAN
NC score	0.074492 (rank : 75)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	271	Target Neighborhood Hits	92	Shared Neighborhood Hits	45
SwissProt Accessions	P50542, Q15115, Q15266	Gene names	PEX5, PXR1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor).

SPAG1_MOUSE
NC score	0.074376 (rank : 76)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	271	Target Neighborhood Hits	218	Shared Neighborhood Hits	47
SwissProt Accessions	Q80ZX8, Q8CCK7, Q9QZJ3, Q9QZJ4	Gene names	Spag1, Tpis
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS).

SPAG1_HUMAN
NC score	0.073077 (rank : 77)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	41
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

IF3X_HUMAN
NC score	0.070424 (rank : 78)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	271	Target Neighborhood Hits	44	Shared Neighborhood Hits	14
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

TTC1_MOUSE
NC score	0.069696 (rank : 79)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	271	Target Neighborhood Hits	145	Shared Neighborhood Hits	33
SwissProt Accessions	Q91Z38, Q3TLM0	Gene names	Ttc1
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

MUC1_MOUSE
NC score	0.069176 (rank : 80)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	271	Target Neighborhood Hits	388	Shared Neighborhood Hits	39
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

UN45A_MOUSE
NC score	0.068670 (rank : 81)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	271	Target Neighborhood Hits	129	Shared Neighborhood Hits	36
SwissProt Accessions	Q99KD5, Q3TKV6, Q8BFT3, Q8C157	Gene names	Unc45a, Smap1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Stromal membrane-associated protein 1) (Smap-1).

NCOA6_HUMAN
NC score	0.066998 (rank : 82)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	271	Target Neighborhood Hits	1202	Shared Neighborhood Hits	99
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

TARA_HUMAN
NC score	0.066881 (rank : 83)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	271	Target Neighborhood Hits	1626	Shared Neighborhood Hits	119
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

OM34_MOUSE
NC score	0.065973 (rank : 84)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	271	Target Neighborhood Hits	82	Shared Neighborhood Hits	31
SwissProt Accessions	Q9CYG7, Q3THD0, Q9D059	Gene names	Tomm34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit).

EVL_HUMAN
NC score	0.064806 (rank : 85)	θ value	0.0431538 (rank : 49)
Query Neighborhood Hits	271	Target Neighborhood Hits	260	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SRRM1_MOUSE
NC score	0.064555 (rank : 86)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	271	Target Neighborhood Hits	966	Shared Neighborhood Hits	81
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TTC1_HUMAN
NC score	0.064201 (rank : 87)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	271	Target Neighborhood Hits	417	Shared Neighborhood Hits	42
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

RAI1_MOUSE
NC score	0.063679 (rank : 88)	θ value	0.00390308 (rank : 31)
Query Neighborhood Hits	271	Target Neighborhood Hits	344	Shared Neighborhood Hits	34
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SRRM2_HUMAN
NC score	0.063137 (rank : 89)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	271	Target Neighborhood Hits	1296	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TTC16_HUMAN
NC score	0.061457 (rank : 90)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	271	Target Neighborhood Hits	417	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

RPB1_HUMAN
NC score	0.061146 (rank : 91)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	271	Target Neighborhood Hits	362	Shared Neighborhood Hits	43
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

DCP1A_HUMAN
NC score	0.061095 (rank : 92)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	271	Target Neighborhood Hits	228	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

RPB1_MOUSE
NC score	0.061074 (rank : 93)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	271	Target Neighborhood Hits	363	Shared Neighborhood Hits	42
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

OM34_HUMAN
NC score	0.059922 (rank : 94)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	271	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	Q15785, Q9NTZ3	Gene names	TOMM34
Domain Architecture
Description	Mitochondrial import receptor subunit TOM34 (Translocase of outer membrane 34 kDa subunit) (hTom34).

PEX5R_MOUSE
NC score	0.059678 (rank : 95)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	271	Target Neighborhood Hits	80	Shared Neighborhood Hits	37
SwissProt Accessions	Q8C437, Q8CA31, Q9DAA1, Q9JMB9	Gene names	Pex5l, Pex2, Pex5r, Pxr2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

EVL_MOUSE
NC score	0.058976 (rank : 96)	θ value	0.0736092 (rank : 55)
Query Neighborhood Hits	271	Target Neighborhood Hits	203	Shared Neighborhood Hits	25
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

TTC16_MOUSE
NC score	0.057451 (rank : 97)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	271	Target Neighborhood Hits	98	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

PEX5R_HUMAN
NC score	0.057396 (rank : 98)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	271	Target Neighborhood Hits	102	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IYB4, Q9NQD1, Q9P2U3, Q9P2U4	Gene names	PEX5L, PEX5R, PXR2
Domain Architecture
Description	PEX5-related protein (Peroxin-5-related protein) (Pex5Rp) (PEX5-like protein) (PEX2-related protein).

TTC14_HUMAN
NC score	0.056976 (rank : 99)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	271	Target Neighborhood Hits	274	Shared Neighborhood Hits	34
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

BSN_MOUSE
NC score	0.055456 (rank : 100)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	271	Target Neighborhood Hits	2057	Shared Neighborhood Hits	124
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NOLC1_HUMAN
NC score	0.055204 (rank : 101)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	271	Target Neighborhood Hits	452	Shared Neighborhood Hits	45
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

AFF1_MOUSE
NC score	0.054988 (rank : 102)	θ value	0.163984 (rank : 64)
Query Neighborhood Hits	271	Target Neighborhood Hits	351	Shared Neighborhood Hits	43
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MUC13_MOUSE
NC score	0.054658 (rank : 103)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	271	Target Neighborhood Hits	447	Shared Neighborhood Hits	37
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

SGIP1_HUMAN
NC score	0.054487 (rank : 104)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	271	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

APC_HUMAN
NC score	0.054119 (rank : 105)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	271	Target Neighborhood Hits	603	Shared Neighborhood Hits	56
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

CJ012_HUMAN
NC score	0.053507 (rank : 106)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	271	Target Neighborhood Hits	467	Shared Neighborhood Hits	53
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

F10A5_HUMAN
NC score	0.053504 (rank : 107)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	271	Target Neighborhood Hits	277	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NFI4	Gene names	FAM10A5
Domain Architecture	No domain graphic available
Description	Protein FAM10A5.

NCOA6_MOUSE
NC score	0.053094 (rank : 108)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	271	Target Neighborhood Hits	1076	Shared Neighborhood Hits	82
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

F10A4_HUMAN
NC score	0.052998 (rank : 109)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	271	Target Neighborhood Hits	249	Shared Neighborhood Hits	34
SwissProt Accessions	Q8IZP2	Gene names	FAM10A4
Domain Architecture	No domain graphic available
Description	Protein FAM10A4.

UN45A_HUMAN
NC score	0.052541 (rank : 110)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	271	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3U1, Q7L3Y6, Q9H3U8, Q9NSE8, Q9NSE9	Gene names	UNC45A, SMAP1
Domain Architecture	No domain graphic available
Description	UNC45 homolog A (UNC-45A) (Smooth muscle cell-associated protein 1) (SMAP-1).

MDC1_HUMAN
NC score	0.051643 (rank : 111)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	271	Target Neighborhood Hits	1446	Shared Neighborhood Hits	99
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

DYXC1_MOUSE
NC score	0.051583 (rank : 112)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	271	Target Neighborhood Hits	172	Shared Neighborhood Hits	28
SwissProt Accessions	Q8R368	Gene names	Dyx1c1, Ekn1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein homolog.

PRG4_MOUSE
NC score	0.051493 (rank : 113)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	271	Target Neighborhood Hits	624	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TP53B_MOUSE
NC score	0.051317 (rank : 114)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	271	Target Neighborhood Hits	644	Shared Neighborhood Hits	64
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

F10A1_MOUSE
NC score	0.050979 (rank : 115)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	271	Target Neighborhood Hits	117	Shared Neighborhood Hits	26
SwissProt Accessions	Q99L47, Q4FJT4	Gene names	St13, Fam10a1, Hip
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Protein ST13 homolog) (Protein FAM10A1).

DYXC1_HUMAN
NC score	0.050634 (rank : 116)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	271	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

APC_MOUSE
NC score	0.050412 (rank : 117)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	271	Target Neighborhood Hits	441	Shared Neighborhood Hits	36
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

SPT5H_MOUSE
NC score	0.050356 (rank : 118)	θ value	1.06291 (rank : 117)
Query Neighborhood Hits	271	Target Neighborhood Hits	437	Shared Neighborhood Hits	39
SwissProt Accessions	O55201, Q3UJ77, Q3UJH1, Q3UKD7, Q3UM54, Q6PB73, Q6PDP0, Q6PFR4	Gene names	Supt5h
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (DRB sensitivity-inducing factor large subunit) (DSIF large subunit).

AIP_MOUSE
NC score	0.050340 (rank : 119)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	271	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	O08915	Gene names	Aip
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein).

TARA_MOUSE
NC score	0.050245 (rank : 120)	θ value	0.21417 (rank : 66)
Query Neighborhood Hits	271	Target Neighborhood Hits	1133	Shared Neighborhood Hits	75
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BSN_HUMAN
NC score	0.050074 (rank : 121)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	271	Target Neighborhood Hits	1537	Shared Neighborhood Hits	107
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

AIP_HUMAN
NC score	0.050041 (rank : 122)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	271	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	O00170, Q99606	Gene names	AIP, XAP2
Domain Architecture
Description	AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor- interacting protein) (Immunophilin homolog ARA9) (HBV-X-associated protein 2).

SPT5H_HUMAN
NC score	0.049288 (rank : 123)	θ value	1.06291 (rank : 116)
Query Neighborhood Hits	271	Target Neighborhood Hits	436	Shared Neighborhood Hits	37
SwissProt Accessions	O00267, O43279, Q59G52, Q99639	Gene names	SUPT5H, SPT5, SPT5H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (DSIF p160) (Tat- cotransactivator 1 protein) (Tat-CT1 protein).

BAP1_MOUSE
NC score	0.048127 (rank : 124)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	271	Target Neighborhood Hits	118	Shared Neighborhood Hits	20
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

NU214_HUMAN
NC score	0.048083 (rank : 125)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	271	Target Neighborhood Hits	657	Shared Neighborhood Hits	60
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

NASP_HUMAN
NC score	0.047599 (rank : 126)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	271	Target Neighborhood Hits	709	Shared Neighborhood Hits	49
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

K1802_MOUSE
NC score	0.047263 (rank : 127)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	271	Target Neighborhood Hits	1596	Shared Neighborhood Hits	90
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PDZD2_HUMAN
NC score	0.046828 (rank : 128)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	271	Target Neighborhood Hits	772	Shared Neighborhood Hits	68
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

NPBL_MOUSE
NC score	0.046594 (rank : 129)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	271	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CBP_MOUSE
NC score	0.045805 (rank : 130)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	271	Target Neighborhood Hits	1051	Shared Neighborhood Hits	81
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CABIN_HUMAN
NC score	0.045659 (rank : 131)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	271	Target Neighborhood Hits	490	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6J0, Q9Y460	Gene names	CABIN1, KIAA0330
Domain Architecture
Description	Calcineurin-binding protein Cabin 1 (Calcineurin inhibitor) (CAIN).

NIPBL_HUMAN
NC score	0.045193 (rank : 132)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	271	Target Neighborhood Hits	1311	Shared Neighborhood Hits	80
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SGIP1_MOUSE
NC score	0.045038 (rank : 133)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	271	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

CBP_HUMAN
NC score	0.044662 (rank : 134)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	271	Target Neighborhood Hits	941	Shared Neighborhood Hits	65
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CK024_MOUSE
NC score	0.043897 (rank : 135)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	271	Target Neighborhood Hits	307	Shared Neighborhood Hits	43
SwissProt Accessions	Q9D8N1, Q8VCP2	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 homolog precursor.

NARGL_HUMAN
NC score	0.043182 (rank : 136)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	271	Target Neighborhood Hits	222	Shared Neighborhood Hits	33
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NARGL_MOUSE
NC score	0.042979 (rank : 137)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	271	Target Neighborhood Hits	175	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

MINT_MOUSE
NC score	0.042353 (rank : 138)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	271	Target Neighborhood Hits	1514	Shared Neighborhood Hits	95
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TAU_HUMAN
NC score	0.042210 (rank : 139)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	271	Target Neighborhood Hits	448	Shared Neighborhood Hits	38
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

MAGE1_HUMAN
NC score	0.042115 (rank : 140)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	271	Target Neighborhood Hits	1389	Shared Neighborhood Hits	98
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RGS3_MOUSE
NC score	0.041657 (rank : 141)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	271	Target Neighborhood Hits	1621	Shared Neighborhood Hits	100
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

KI67_HUMAN
NC score	0.040906 (rank : 142)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	271	Target Neighborhood Hits	581	Shared Neighborhood Hits	55
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

K1802_HUMAN
NC score	0.040852 (rank : 143)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	271	Target Neighborhood Hits	1378	Shared Neighborhood Hits	80
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PO121_MOUSE
NC score	0.040741 (rank : 144)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	271	Target Neighborhood Hits	345	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

AFF1_HUMAN
NC score	0.040577 (rank : 145)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	271	Target Neighborhood Hits	506	Shared Neighborhood Hits	52
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SEN34_MOUSE
NC score	0.039194 (rank : 146)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	271	Target Neighborhood Hits	158	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

CBL_MOUSE
NC score	0.037572 (rank : 147)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	271	Target Neighborhood Hits	426	Shared Neighborhood Hits	33
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

ZN318_HUMAN
NC score	0.036341 (rank : 148)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	271	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	Q5VUA4, O94796, Q4G0E4, Q8NEM6, Q9UNU8, Q9Y2W9	Gene names	ZNF318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Endocrine regulatory protein).

YETS2_MOUSE
NC score	0.035176 (rank : 149)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	271	Target Neighborhood Hits	278	Shared Neighborhood Hits	31
SwissProt Accessions	Q3TUF7, Q6PGF8, Q80TI2, Q8CG86	Gene names	Yeats2, Kiaa1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

ARI5B_HUMAN
NC score	0.034853 (rank : 150)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	271	Target Neighborhood Hits	328	Shared Neighborhood Hits	31
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

SETBP_MOUSE
NC score	0.034707 (rank : 151)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	271	Target Neighborhood Hits	352	Shared Neighborhood Hits	42
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ICAL_MOUSE
NC score	0.034410 (rank : 152)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	271	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	P51125, Q9EQV4, Q9EQV5, Q9QXQ3, Q9QXQ4, Q9R0N1	Gene names	Cast
Domain Architecture
Description	Calpastatin (Calpain inhibitor).

CENPC_MOUSE
NC score	0.033964 (rank : 153)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	271	Target Neighborhood Hits	154	Shared Neighborhood Hits	15
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

PPRB_MOUSE
NC score	0.033372 (rank : 154)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	271	Target Neighborhood Hits	354	Shared Neighborhood Hits	39
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RP1L1_HUMAN
NC score	0.031546 (rank : 155)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	271	Target Neighborhood Hits	1072	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ALO17_HUMAN
NC score	0.030680 (rank : 156)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	271	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

SAMD4_HUMAN
NC score	0.030411 (rank : 157)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	271	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

BIG1_HUMAN
NC score	0.030145 (rank : 158)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	271	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

MUC2_HUMAN
NC score	0.030062 (rank : 159)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	271	Target Neighborhood Hits	906	Shared Neighborhood Hits	61
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

DAB2_MOUSE
NC score	0.029705 (rank : 160)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	271	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

IRS2_MOUSE
NC score	0.029464 (rank : 161)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	271	Target Neighborhood Hits	248	Shared Neighborhood Hits	24
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

IF4B_MOUSE
NC score	0.029461 (rank : 162)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	271	Target Neighborhood Hits	368	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

UBP31_HUMAN
NC score	0.029173 (rank : 163)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	271	Target Neighborhood Hits	293	Shared Neighborhood Hits	31
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

EXDL2_MOUSE
NC score	0.028658 (rank : 164)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	271	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VEG4	Gene names	Exdl2
Domain Architecture
Description	Exonuclease 3'-5' domain-like-containing protein 2.

CP250_MOUSE
NC score	0.028602 (rank : 165)	θ value	0.125558 (rank : 63)
Query Neighborhood Hits	271	Target Neighborhood Hits	1583	Shared Neighborhood Hits	55
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

SF3A1_HUMAN
NC score	0.028571 (rank : 166)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	271	Target Neighborhood Hits	199	Shared Neighborhood Hits	17
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

PI5PA_HUMAN
NC score	0.028318 (rank : 167)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	271	Target Neighborhood Hits	749	Shared Neighborhood Hits	57
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

ZC313_HUMAN
NC score	0.028247 (rank : 168)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	271	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

SRBP1_MOUSE
NC score	0.028161 (rank : 169)	θ value	1.81305 (rank : 140)
Query Neighborhood Hits	271	Target Neighborhood Hits	384	Shared Neighborhood Hits	30
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ANC5_MOUSE
NC score	0.027675 (rank : 170)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	271	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BTZ4, Q3TGA7, Q80UJ6, Q80W43, Q8BWW7, Q8C0F7, Q9CRX0, Q9CSL1, Q9JJB8	Gene names	Anapc5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

SI1L2_MOUSE
NC score	0.027224 (rank : 171)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	271	Target Neighborhood Hits	124	Shared Neighborhood Hits	9
SwissProt Accessions	Q80TE4, Q6PDY1	Gene names	Sipa1l2, Kiaa0545
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 2.

CAF1A_MOUSE
NC score	0.027157 (rank : 172)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	271	Target Neighborhood Hits	736	Shared Neighborhood Hits	36
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

DPOLZ_HUMAN
NC score	0.027040 (rank : 173)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	271	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

CP250_HUMAN
NC score	0.026813 (rank : 174)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	271	Target Neighborhood Hits	1805	Shared Neighborhood Hits	68
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MAP2_HUMAN
NC score	0.026695 (rank : 175)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	271	Target Neighborhood Hits	348	Shared Neighborhood Hits	31
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

CO039_HUMAN
NC score	0.026620 (rank : 176)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	271	Target Neighborhood Hits	264	Shared Neighborhood Hits	25
SwissProt Accessions	Q6ZRI6, Q71JB1, Q7L3S0, Q8N3F2, Q96FB6, Q9NTU5	Gene names	C15orf39
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39.

DAB2_HUMAN
NC score	0.025908 (rank : 177)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	29
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

NDC1_MOUSE
NC score	0.025834 (rank : 178)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	271	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VCB1	Gene names	Tmem48, Ndc1
Domain Architecture	No domain graphic available
Description	Nucleoporin NDC1 (Transmembrane protein 48).

NFH_HUMAN
NC score	0.024945 (rank : 179)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	271	Target Neighborhood Hits	1242	Shared Neighborhood Hits	75
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ZEP1_HUMAN
NC score	0.024195 (rank : 180)	θ value	0.21417 (rank : 67)
Query Neighborhood Hits	271	Target Neighborhood Hits	1036	Shared Neighborhood Hits	52
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

CCNB3_HUMAN
NC score	0.023755 (rank : 181)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	271	Target Neighborhood Hits	368	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

NHS_HUMAN
NC score	0.023590 (rank : 182)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	271	Target Neighborhood Hits	198	Shared Neighborhood Hits	24
SwissProt Accessions	Q6T4R5, Q5J7Q0, Q5J7Q1, Q68DR5	Gene names	NHS
Domain Architecture	No domain graphic available
Description	Nance-Horan syndrome protein (Congenital cataracts and dental anomalies protein).

PO6F2_HUMAN
NC score	0.023338 (rank : 183)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	271	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

MYST3_HUMAN
NC score	0.022869 (rank : 184)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	271	Target Neighborhood Hits	772	Shared Neighborhood Hits	50
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MAGD4_HUMAN
NC score	0.022587 (rank : 185)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	271	Target Neighborhood Hits	338	Shared Neighborhood Hits	43
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

LMO7_HUMAN
NC score	0.022573 (rank : 186)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	271	Target Neighborhood Hits	507	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

WNK4_HUMAN
NC score	0.022487 (rank : 187)	θ value	0.0148317 (rank : 40)
Query Neighborhood Hits	271	Target Neighborhood Hits	1043	Shared Neighborhood Hits	48
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TACC1_MOUSE
NC score	0.022399 (rank : 188)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	271	Target Neighborhood Hits	667	Shared Neighborhood Hits	34
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TACC1_HUMAN
NC score	0.022135 (rank : 189)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	271	Target Neighborhood Hits	597	Shared Neighborhood Hits	27
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

CUL7_HUMAN
NC score	0.021849 (rank : 190)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	271	Target Neighborhood Hits	41	Shared Neighborhood Hits	5
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

ZCH10_MOUSE
NC score	0.021633 (rank : 191)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	271	Target Neighborhood Hits	133	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

PAPOA_HUMAN
NC score	0.021494 (rank : 192)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	271	Target Neighborhood Hits	75	Shared Neighborhood Hits	11
SwissProt Accessions	P51003, Q86SX4, Q86TV0, Q8IYF5, Q9BVU2	Gene names	PAPOLA, PAP
Domain Architecture	No domain graphic available
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase alpha).

TBCD4_HUMAN
NC score	0.021130 (rank : 193)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	271	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

MAST4_HUMAN
NC score	0.020726 (rank : 194)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	271	Target Neighborhood Hits	1804	Shared Neighborhood Hits	94
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ABI2_HUMAN
NC score	0.020637 (rank : 195)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	271	Target Neighborhood Hits	350	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYB9, Q13147, Q13249, Q13801, Q9BV70	Gene names	ABI2, ARGBPIA
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1).

LIPA3_HUMAN
NC score	0.020556 (rank : 196)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	271	Target Neighborhood Hits	828	Shared Neighborhood Hits	34
SwissProt Accessions	O75145, Q9H8B5, Q9UEW4	Gene names	PPFIA3, KIAA0654
Domain Architecture
Description	Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3).

IL3B2_MOUSE
NC score	0.020520 (rank : 197)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	271	Target Neighborhood Hits	372	Shared Neighborhood Hits	23
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

5NT1B_HUMAN
NC score	0.020335 (rank : 198)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	271	Target Neighborhood Hits	83	Shared Neighborhood Hits	14
SwissProt Accessions	Q96P26, Q8N9W3, Q8NA26, Q96DU5, Q96KE6, Q96M25, Q96SA3	Gene names	NT5C1B, AIRP
Domain Architecture
Description	Cytosolic 5'-nucleotidase 1B (EC 3.1.3.5) (Cytosolic 5'-nucleotidase IB) (cN1B) (cN-IB) (Autoimmune infertility-related protein).

LAMC2_HUMAN
NC score	0.019969 (rank : 199)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	271	Target Neighborhood Hits	715	Shared Neighborhood Hits	18
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

RUSC1_HUMAN
NC score	0.019898 (rank : 200)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	271	Target Neighborhood Hits	226	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

BRDT_MOUSE
NC score	0.019801 (rank : 201)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	271	Target Neighborhood Hits	243	Shared Neighborhood Hits	18
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CNKR2_MOUSE
NC score	0.019486 (rank : 202)	θ value	5.27518 (rank : 191)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.019482 (rank : 203)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	271	Target Neighborhood Hits	197	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

NFAC1_MOUSE
NC score	0.019211 (rank : 204)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	271	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	O88942, O70345	Gene names	Nfatc1, Nfat2, Nfatc
Domain Architecture
Description	Nuclear factor of activated T-cells, cytoplasmic 1 (NFAT transcription complex cytosolic component) (NF-ATc1) (NF-ATc).

CSKI2_MOUSE
NC score	0.018799 (rank : 205)	θ value	5.27518 (rank : 192)
Query Neighborhood Hits	271	Target Neighborhood Hits	812	Shared Neighborhood Hits	45
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

HES7_HUMAN
NC score	0.018786 (rank : 206)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	271	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

CNTP4_MOUSE
NC score	0.018684 (rank : 207)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	271	Target Neighborhood Hits	193	Shared Neighborhood Hits	5
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

NCOA2_HUMAN
NC score	0.018669 (rank : 208)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	271	Target Neighborhood Hits	281	Shared Neighborhood Hits	34
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

PININ_HUMAN
NC score	0.018561 (rank : 209)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	271	Target Neighborhood Hits	753	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CSKI2_HUMAN
NC score	0.018279 (rank : 210)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	271	Target Neighborhood Hits	747	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SYNP2_MOUSE
NC score	0.018228 (rank : 211)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	271	Target Neighborhood Hits	252	Shared Neighborhood Hits	20
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

LYPD3_HUMAN
NC score	0.017632 (rank : 212)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	271	Target Neighborhood Hits	43	Shared Neighborhood Hits	9
SwissProt Accessions	O95274, Q9UJ74	Gene names	LYPD3, C4.4A
Domain Architecture	No domain graphic available
Description	Ly6/PLAUR domain-containing protein 3 precursor (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4).

ANK3_HUMAN
NC score	0.017427 (rank : 213)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	271	Target Neighborhood Hits	853	Shared Neighborhood Hits	55
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MYST3_MOUSE
NC score	0.017282 (rank : 214)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	271	Target Neighborhood Hits	688	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

WNK4_MOUSE
NC score	0.016956 (rank : 215)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	271	Target Neighborhood Hits	961	Shared Neighborhood Hits	37
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TOP1M_HUMAN
NC score	0.016736 (rank : 216)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	271	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	Q969P6	Gene names	TOP1MT
Domain Architecture
Description	DNA topoisomerase I, mitochondrial precursor (EC 5.99.1.2) (TOP1mt).

NCOA2_MOUSE
NC score	0.016726 (rank : 217)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	271	Target Neighborhood Hits	281	Shared Neighborhood Hits	25
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

ZBTB3_HUMAN
NC score	0.016671 (rank : 218)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	271	Target Neighborhood Hits	910	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

PTN23_MOUSE
NC score	0.016241 (rank : 219)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	271	Target Neighborhood Hits	726	Shared Neighborhood Hits	54
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTC1_MOUSE
NC score	0.016030 (rank : 220)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	271	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q61115	Gene names	Ptch1, Ptch
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

MINK1_MOUSE
NC score	0.015978 (rank : 221)	θ value	0.000602161 (rank : 22)
Query Neighborhood Hits	271	Target Neighborhood Hits	1451	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

JHD2C_HUMAN
NC score	0.015800 (rank : 222)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	271	Target Neighborhood Hits	279	Shared Neighborhood Hits	25
SwissProt Accessions	Q15652, Q5SQZ8, Q5SQZ9, Q5SR00, Q7Z3E7, Q8N3U0, Q96KB9, Q9P2G7	Gene names	JMJD1C, JHDM2C, KIAA1380, TRIP8
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TRIP-8).

NOTC1_MOUSE
NC score	0.015394 (rank : 223)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	271	Target Neighborhood Hits	916	Shared Neighborhood Hits	19
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SETD2_HUMAN
NC score	0.015286 (rank : 224)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	271	Target Neighborhood Hits	412	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EMIL2_HUMAN
NC score	0.015058 (rank : 225)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	271	Target Neighborhood Hits	573	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

CHD9_MOUSE
NC score	0.014981 (rank : 226)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	271	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

EGR1_MOUSE
NC score	0.014893 (rank : 227)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	271	Target Neighborhood Hits	816	Shared Neighborhood Hits	24
SwissProt Accessions	P08046, Q61777	Gene names	Egr1, Egr-1, Krox-24
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A).

MTG8R_HUMAN
NC score	0.014872 (rank : 228)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	271	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

DYNA_HUMAN
NC score	0.014829 (rank : 229)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	271	Target Neighborhood Hits	1194	Shared Neighborhood Hits	45
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

UBF1_MOUSE
NC score	0.014662 (rank : 230)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	271	Target Neighborhood Hits	419	Shared Neighborhood Hits	22
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

MEF2D_MOUSE
NC score	0.014496 (rank : 231)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	271	Target Neighborhood Hits	146	Shared Neighborhood Hits	14
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

EGR1_HUMAN
NC score	0.014026 (rank : 232)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	271	Target Neighborhood Hits	788	Shared Neighborhood Hits	20
SwissProt Accessions	P18146	Gene names	EGR1, ZNF225
Domain Architecture
Description	Early growth response protein 1 (EGR-1) (Krox-24 protein) (Transcription factor Zif268) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Zinc finger protein 225) (AT225).

RHG25_MOUSE
NC score	0.013967 (rank : 233)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	271	Target Neighborhood Hits	492	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

ARHGB_HUMAN
NC score	0.013770 (rank : 234)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	271	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	O15085	Gene names	ARHGEF11, KIAA0380
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF).

OPHN1_MOUSE
NC score	0.013621 (rank : 235)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	271	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

HCN2_MOUSE
NC score	0.013318 (rank : 236)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	271	Target Neighborhood Hits	278	Shared Neighborhood Hits	33
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

SOX13_HUMAN
NC score	0.013203 (rank : 237)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	271	Target Neighborhood Hits	464	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

CMTA2_MOUSE
NC score	0.013123 (rank : 238)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	271	Target Neighborhood Hits	216	Shared Neighborhood Hits	18
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ETV5_MOUSE
NC score	0.013119 (rank : 239)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	271	Target Neighborhood Hits	328	Shared Neighborhood Hits	25
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

PXK_HUMAN
NC score	0.013038 (rank : 240)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	271	Target Neighborhood Hits	216	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z7A4, Q3BCH4, Q3BCH5, Q3BCH6, Q3BDW1, Q45L83, Q59EX3, Q6PK17, Q6ZN39, Q96CA3, Q96R07, Q9NXB8	Gene names	PXK
Domain Architecture	No domain graphic available
Description	PX domain-containing protein kinase-like protein (Modulator of Na,K- ATPase) (MONaKA).

GMEB2_MOUSE
NC score	0.012720 (rank : 241)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	271	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

SPEG_MOUSE
NC score	0.012462 (rank : 242)	θ value	1.81305 (rank : 139)
Query Neighborhood Hits	271	Target Neighborhood Hits	1959	Shared Neighborhood Hits	81
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DYNA_MOUSE
NC score	0.012363 (rank : 243)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	271	Target Neighborhood Hits	1084	Shared Neighborhood Hits	41
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

NOTC1_HUMAN
NC score	0.012044 (rank : 244)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	271	Target Neighborhood Hits	906	Shared Neighborhood Hits	19
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

EYA4_HUMAN
NC score	0.011999 (rank : 245)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	271	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

RAI14_MOUSE
NC score	0.011965 (rank : 246)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	271	Target Neighborhood Hits	1505	Shared Neighborhood Hits	60
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CXCC1_MOUSE
NC score	0.011745 (rank : 247)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	271	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

FOXJ3_HUMAN
NC score	0.011707 (rank : 248)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	271	Target Neighborhood Hits	177	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UPW0, Q9NSS7	Gene names	FOXJ3, KIAA1041
Domain Architecture
Description	Forkhead box protein J3.

ARNT_MOUSE
NC score	0.011686 (rank : 249)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	271	Target Neighborhood Hits	213	Shared Neighborhood Hits	17
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

LIPB2_MOUSE
NC score	0.011657 (rank : 250)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	271	Target Neighborhood Hits	570	Shared Neighborhood Hits	23
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

ETV5_HUMAN
NC score	0.011407 (rank : 251)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	271	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

TEF_MOUSE
NC score	0.011375 (rank : 252)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	271	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JLC6, Q3U426, Q3UGF4, Q3UM49, Q3URC8, Q6QHT6, Q8C6I0, Q8VD02	Gene names	Tef
Domain Architecture	No domain graphic available
Description	Thyrotroph embryonic factor.

SREC2_MOUSE
NC score	0.011327 (rank : 253)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	271	Target Neighborhood Hits	605	Shared Neighborhood Hits	29
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

VAX2_HUMAN
NC score	0.011219 (rank : 254)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	271	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIW0	Gene names	VAX2
Domain Architecture
Description	Ventral anterior homeobox 2.

SPTA1_MOUSE
NC score	0.011128 (rank : 255)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	271	Target Neighborhood Hits	675	Shared Neighborhood Hits	20
SwissProt Accessions	P08032, P97502	Gene names	Spta1, Spna1, Spta
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

AF10_HUMAN
NC score	0.011033 (rank : 256)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	271	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

APOB_HUMAN
NC score	0.011015 (rank : 257)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	271	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	P04114, O00502, P78479, P78480, P78481, Q13779, Q13785, Q13786, Q13787, Q13788, Q7Z600, Q9UMN0	Gene names	APOB
Domain Architecture
Description	Apolipoprotein B-100 precursor (Apo B-100) [Contains: Apolipoprotein B-48 (Apo B-48)].

HCN1_MOUSE
NC score	0.010514 (rank : 258)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	271	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

SPTA1_HUMAN
NC score	0.010509 (rank : 259)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	271	Target Neighborhood Hits	748	Shared Neighborhood Hits	24
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

HXB5_HUMAN
NC score	0.010245 (rank : 260)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	271	Target Neighborhood Hits	332	Shared Neighborhood Hits	11
SwissProt Accessions	P09067, P09069	Gene names	HOXB5, HOX2A
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2A) (HHO.C10) (HU-1).

ZO1_HUMAN
NC score	0.010048 (rank : 261)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	271	Target Neighborhood Hits	474	Shared Neighborhood Hits	35
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

TITIN_HUMAN
NC score	0.010005 (rank : 262)	θ value	1.81305 (rank : 142)
Query Neighborhood Hits	271	Target Neighborhood Hits	2923	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

HXB5_MOUSE
NC score	0.009545 (rank : 263)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	271	Target Neighborhood Hits	337	Shared Neighborhood Hits	11
SwissProt Accessions	P09079, Q3ZAY8	Gene names	Hoxb5, Hox-2.1, Hoxb-5
Domain Architecture
Description	Homeobox protein Hox-B5 (Hox-2.1) (MU-1) (H24.1).

LAMP1_HUMAN
NC score	0.009493 (rank : 264)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	271	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	P11279	Gene names	LAMP1
Domain Architecture
Description	Lysosome-associated membrane glycoprotein 1 precursor (LAMP-1) (CD107a antigen).

TBX18_MOUSE
NC score	0.009474 (rank : 265)	θ value	1.81305 (rank : 141)
Query Neighborhood Hits	271	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPZ6	Gene names	Tbx18
Domain Architecture
Description	T-box transcription factor TBX18 (T-box protein 18).

TTBK2_HUMAN
NC score	0.009305 (rank : 266)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	271	Target Neighborhood Hits	822	Shared Neighborhood Hits	29
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

FOG1_MOUSE
NC score	0.009261 (rank : 267)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	271	Target Neighborhood Hits	1237	Shared Neighborhood Hits	53
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

GP1BA_HUMAN
NC score	0.009247 (rank : 268)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	271	Target Neighborhood Hits	407	Shared Neighborhood Hits	16
SwissProt Accessions	P07359, Q14441, Q16469, Q8N1F3, Q8NG39, Q9HDC7, Q9UEK1, Q9UQS4	Gene names	GP1BA
Domain Architecture
Description	Platelet glycoprotein Ib alpha chain precursor (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (Antigen CD42b-alpha) (CD42b antigen) [Contains: Glycocalicin].

SNAA_HUMAN
NC score	0.008740 (rank : 269)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	271	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P54920, Q96IK3, Q9BVJ3	Gene names	NAPA, SNAPA
Domain Architecture	No domain graphic available
Description	Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide- sensitive factor attachment protein, alpha).

RBM4B_HUMAN
NC score	0.008710 (rank : 270)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	271	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQ04	Gene names	RBM4B, RBM30
Domain Architecture	No domain graphic available
Description	RNA-binding protein 4B (RNA-binding motif protein 4B) (RNA-binding protein 30) (RNA-binding motif protein 30).

HCN1_HUMAN
NC score	0.008593 (rank : 271)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	271	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

DDX20_MOUSE
NC score	0.008422 (rank : 272)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	271	Target Neighborhood Hits	177	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JJY4, Q9JIK4	Gene names	Ddx20, Dp103, Gemin3
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.-) (DEAD box protein 20) (DEAD box protein DP 103) (Component of gems 3) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1).

MY18A_HUMAN
NC score	0.008355 (rank : 273)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	271	Target Neighborhood Hits	1929	Shared Neighborhood Hits	67
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

VAX2_MOUSE
NC score	0.008027 (rank : 274)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	271	Target Neighborhood Hits	338	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTP9	Gene names	Vax2, Vex
Domain Architecture	No domain graphic available
Description	Ventral anterior homeobox 2 (Ventral retina homeodomain protein).

TTBK2_MOUSE
NC score	0.007970 (rank : 275)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	271	Target Neighborhood Hits	811	Shared Neighborhood Hits	27
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

WDR22_MOUSE
NC score	0.007761 (rank : 276)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	271	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	Q80T85, Q80VT3, Q80ZW6, Q8BIP8, Q8BVK5, Q8K0Q6	Gene names	Wdr22, Kiaa1824
Domain Architecture
Description	WD repeat protein 22.

CAC1E_HUMAN
NC score	0.007638 (rank : 277)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	271	Target Neighborhood Hits	148	Shared Neighborhood Hits	13
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

PA24D_HUMAN
NC score	0.007599 (rank : 278)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	271	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XP0, Q8N176	Gene names	PLA2G4D
Domain Architecture	No domain graphic available
Description	Cytosolic phospholipase A2 delta (EC 3.1.1.4) (cPLA2-delta) (Phospholipase A2 group IVD).

SM1L2_HUMAN
NC score	0.007527 (rank : 279)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	271	Target Neighborhood Hits	1019	Shared Neighborhood Hits	36
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

CAC1E_MOUSE
NC score	0.007042 (rank : 280)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	271	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CD2L7_HUMAN
NC score	0.006972 (rank : 281)	θ value	6.88961 (rank : 216)
Query Neighborhood Hits	271	Target Neighborhood Hits	1275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NYV4, O94978	Gene names	CRKRS, CRK7, KIAA0904
Domain Architecture
Description	Cell division cycle 2-related protein kinase 7 (EC 2.7.11.22) (CDC2- related protein kinase 7) (Cdc2-related kinase, arginine/serine-rich) (CrkRS).

MARK2_HUMAN
NC score	0.006669 (rank : 282)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	271	Target Neighborhood Hits	1056	Shared Neighborhood Hits	36
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

FARP2_MOUSE
NC score	0.006473 (rank : 283)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	271	Target Neighborhood Hits	209	Shared Neighborhood Hits	18
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

IRX1_HUMAN
NC score	0.006399 (rank : 284)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	271	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	P78414, Q7Z2F8, Q8N312	Gene names	IRX1, IRXA1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-1 (Iroquois homeobox protein 1) (Homeodomain protein IRXA1).

M3K3_MOUSE
NC score	0.006394 (rank : 285)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	271	Target Neighborhood Hits	876	Shared Neighborhood Hits	22
SwissProt Accessions	Q61084	Gene names	Map3k3, Mekk3
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3).

MRCKB_MOUSE
NC score	0.006249 (rank : 286)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	271	Target Neighborhood Hits	2180	Shared Neighborhood Hits	64
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

DVL1_MOUSE
NC score	0.005822 (rank : 287)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	271	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	P51141, Q60868	Gene names	Dvl1, Dvl
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1).

DUET_HUMAN
NC score	0.005607 (rank : 288)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	271	Target Neighborhood Hits	1220	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

SSPO_MOUSE
NC score	0.005554 (rank : 289)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	271	Target Neighborhood Hits	800	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

NEK4_MOUSE
NC score	0.005006 (rank : 290)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	271	Target Neighborhood Hits	899	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

ABL1_MOUSE
NC score	0.004737 (rank : 291)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	271	Target Neighborhood Hits	1178	Shared Neighborhood Hits	40
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABCA1_MOUSE
NC score	0.003454 (rank : 292)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	271	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	P41233	Gene names	Abca1, Abc1
Domain Architecture
Description	ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ATP-binding cassette 1) (ABC-1).

GLI1_MOUSE
NC score	0.003062 (rank : 293)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	271	Target Neighborhood Hits	785	Shared Neighborhood Hits	18
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

NR1D1_HUMAN
NC score	0.002525 (rank : 294)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	271	Target Neighborhood Hits	140	Shared Neighborhood Hits	9
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

MAK_HUMAN
NC score	0.002501 (rank : 295)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	271	Target Neighborhood Hits	857	Shared Neighborhood Hits	19
SwissProt Accessions	P20794, Q9NUH7	Gene names	MAK
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase).

DSG2_HUMAN
NC score	0.002402 (rank : 296)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	271	Target Neighborhood Hits	192	Shared Neighborhood Hits	5
SwissProt Accessions	Q14126	Gene names	DSG2
Domain Architecture
Description	Desmoglein-2 precursor (HDGC).

HRH1_MOUSE
NC score	0.000430 (rank : 297)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	271	Target Neighborhood Hits	896	Shared Neighborhood Hits	4
SwissProt Accessions	P70174, Q91V75, Q91XN0, Q91XN1, Q91XN2, Q91XN3	Gene names	Hrh1, Bphs
Domain Architecture
Description	Histamine H1 receptor.

ZFP27_MOUSE
NC score	-0.000308 (rank : 298)	θ value	1.81305 (rank : 143)
Query Neighborhood Hits	271	Target Neighborhood Hits	764	Shared Neighborhood Hits	11
SwissProt Accessions	P10077, Q6PCZ6, Q8CED4	Gene names	Zfp27, Mkr4, Zfp-27
Domain Architecture	No domain graphic available
Description	Zinc finger protein 27 (Zfp-27) (Protein mKR4).