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Network neighborhood for query Sequence : FANCG_HUMAN

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FANCG_HUMAN
SwissProt Accessions	O15287	Gene names	FANCG, XRCC9
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein (Protein FACG) (DNA-repair protein XRCC9).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FANCG_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O15287	Gene names	FANCG, XRCC9
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein (Protein FACG) (DNA-repair protein XRCC9).

FANCG_MOUSE
θ value	0 (rank : 2)	NC score	0.982915 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQR6	Gene names	Fancg
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein homolog (Protein FACG).

TOM70_HUMAN
θ value	0.00869519 (rank : 3)	NC score	0.103011 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TTC14_HUMAN
θ value	0.0193708 (rank : 4)	NC score	0.148227 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TOM70_MOUSE
θ value	0.0330416 (rank : 5)	NC score	0.094587 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TTC28_HUMAN
θ value	0.0961366 (rank : 6)	NC score	0.082341 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC28_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.079991 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ANXA4_HUMAN
θ value	2.36792 (rank : 8)	NC score	0.018112 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P09525, Q96F33, Q9BWK1	Gene names	ANXA4, ANX4
Domain Architecture
Description	Annexin A4 (Annexin IV) (Lipocortin IV) (Endonexin I) (Chromobindin-4) (Protein II) (P32.5) (Placental anticoagulant protein II) (PAP-II) (PP4-X) (35-beta calcimedin) (Carbohydrate-binding protein P33/P41) (P33/41).

ERCC2_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.041079 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P18074, Q8N721	Gene names	ERCC2, XPD, XPDC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

ERCC2_MOUSE
θ value	2.36792 (rank : 10)	NC score	0.041005 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08811, Q9DC01	Gene names	Ercc2, Xpd
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

ANXA4_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.016623 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P97429	Gene names	Anxa4, Anx4
Domain Architecture
Description	Annexin A4 (Annexin IV).

SRBP1_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.019830 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	384	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

FAS_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.017456 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

CHD8_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.007293 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CLC4F_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.006559 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	572	Shared Neighborhood Hits	2
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).

PIAS2_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.010989 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O75928, O75927, Q96BT5, Q96KE3	Gene names	PIAS2, PIASX
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (Miz1) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) (PIAS-NY protein).

FETUB_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.016171 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

Hits sorted by NC score

FANCG_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	O15287	Gene names	FANCG, XRCC9
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein (Protein FACG) (DNA-repair protein XRCC9).

FANCG_MOUSE
NC score	0.982915 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQR6	Gene names	Fancg
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein homolog (Protein FACG).

TTC14_HUMAN
NC score	0.148227 (rank : 3)	θ value	0.0193708 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q96N46, Q6UWJ7, Q8TF22	Gene names	TTC14, KIAA1980
Domain Architecture
Description	Tetratricopeptide repeat protein 14 (TPR repeat protein 14).

TOM70_HUMAN
NC score	0.103011 (rank : 4)	θ value	0.00869519 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	127	Shared Neighborhood Hits	7
SwissProt Accessions	O94826	Gene names	TOMM70A, KIAA0719
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TOM70_MOUSE
NC score	0.094587 (rank : 5)	θ value	0.0330416 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	102	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZW5	Gene names	Tomm70a, D16Wsu109e
Domain Architecture
Description	Mitochondrial precursor proteins import receptor (Translocase of outer membrane TOM70).

TTC28_HUMAN
NC score	0.082341 (rank : 6)	θ value	0.0961366 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	271	Shared Neighborhood Hits	6
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

TTC28_MOUSE
NC score	0.079991 (rank : 7)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	194	Shared Neighborhood Hits	5
SwissProt Accessions	Q80XJ3, Q6P9J6, Q80TL5, Q8BV10, Q8C0F2	Gene names	Ttc28, Kiaa1043
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

ERCC2_HUMAN
NC score	0.041079 (rank : 8)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P18074, Q8N721	Gene names	ERCC2, XPD, XPDC
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

ERCC2_MOUSE
NC score	0.041005 (rank : 9)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	O08811, Q9DC01	Gene names	Ercc2, Xpd
Domain Architecture
Description	TFIIH basal transcription factor complex helicase subunit (EC 3.6.1.-) (DNA-repair protein complementing XP-D cells) (Xeroderma pigmentosum group D-complementing protein) (CXPD) (DNA excision repair protein ERCC-2).

SRBP1_MOUSE
NC score	0.019830 (rank : 10)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	384	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ANXA4_HUMAN
NC score	0.018112 (rank : 11)	θ value	2.36792 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P09525, Q96F33, Q9BWK1	Gene names	ANXA4, ANX4
Domain Architecture
Description	Annexin A4 (Annexin IV) (Lipocortin IV) (Endonexin I) (Chromobindin-4) (Protein II) (P32.5) (Placental anticoagulant protein II) (PAP-II) (PP4-X) (35-beta calcimedin) (Carbohydrate-binding protein P33/P41) (P33/41).

FAS_MOUSE
NC score	0.017456 (rank : 12)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P19096, Q6PB72, Q8C4Z0, Q9EQR0	Gene names	Fasn
Domain Architecture	No domain graphic available
Description	Fatty acid synthase (EC 2.3.1.85) [Includes: [Acyl-carrier-protein] S- acetyltransferase (EC 2.3.1.38); [Acyl-carrier-protein] S- malonyltransferase (EC 2.3.1.39); 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41); 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100); 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61); Enoyl-[acyl-carrier-protein] reductase (EC 1.3.1.10); Oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14)].

ANXA4_MOUSE
NC score	0.016623 (rank : 13)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P97429	Gene names	Anxa4, Anx4
Domain Architecture
Description	Annexin A4 (Annexin IV).

FETUB_HUMAN
NC score	0.016171 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM5, Q1RMZ0, Q6DK58, Q6GRB6, Q9Y6Z0	Gene names	FETUB
Domain Architecture
Description	Fetuin-B precursor (Gugu) (IRL685) (16G2).

PIAS2_HUMAN
NC score	0.010989 (rank : 15)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	O75928, O75927, Q96BT5, Q96KE3	Gene names	PIAS2, PIASX
Domain Architecture	No domain graphic available
Description	Protein inhibitor of activated STAT2 (Protein inhibitor of activated STAT x) (Msx-interacting zinc finger protein) (Miz1) (DAB2-interacting protein) (DIP) (Androgen receptor-interacting protein 3) (ARIP3) (PIAS-NY protein).

CHD8_HUMAN
NC score	0.007293 (rank : 16)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CLC4F_MOUSE
NC score	0.006559 (rank : 17)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	572	Shared Neighborhood Hits	2
SwissProt Accessions	P70194, Q8BLZ8	Gene names	Clec4f, Clecsf13, Kclr
Domain Architecture
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13) (Kupffer cell receptor).