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Network neighborhood for query Sequence : ARNT_MOUSE

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ARNT_MOUSE
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ARNT2_HUMAN
θ value	0 (rank : 1)	NC score	0.973755 (rank : 3)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0 (rank : 2)	NC score	0.972909 (rank : 4)
Query Neighborhood Hits	213	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
θ value	0 (rank : 3)	NC score	0.983049 (rank : 2)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	213	Target Neighborhood Hits	213	Shared Neighborhood Hits	213
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

BMAL1_MOUSE
θ value	2.08775e-89 (rank : 5)	NC score	0.922969 (rank : 6)
Query Neighborhood Hits	213	Target Neighborhood Hits	121	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

BMAL1_HUMAN
θ value	4.65103e-89 (rank : 6)	NC score	0.924801 (rank : 5)
Query Neighborhood Hits	213	Target Neighborhood Hits	115	Shared Neighborhood Hits	70
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

NPAS2_HUMAN
θ value	8.91499e-32 (rank : 7)	NC score	0.794288 (rank : 9)
Query Neighborhood Hits	213	Target Neighborhood Hits	150	Shared Neighborhood Hits	66
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

CLOCK_MOUSE
θ value	4.42448e-31 (rank : 8)	NC score	0.795993 (rank : 7)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
θ value	1.28732e-30 (rank : 9)	NC score	0.795021 (rank : 8)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	65
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

NPAS2_MOUSE
θ value	2.19584e-30 (rank : 10)	NC score	0.794218 (rank : 10)
Query Neighborhood Hits	213	Target Neighborhood Hits	132	Shared Neighborhood Hits	67
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

EPAS1_MOUSE
θ value	8.3442e-30 (rank : 11)	NC score	0.775106 (rank : 11)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
θ value	1.08979e-29 (rank : 12)	NC score	0.774905 (rank : 12)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HIF1A_HUMAN
θ value	5.06226e-27 (rank : 13)	NC score	0.762996 (rank : 13)
Query Neighborhood Hits	213	Target Neighborhood Hits	118	Shared Neighborhood Hits	47
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
θ value	1.47289e-26 (rank : 14)	NC score	0.762959 (rank : 14)
Query Neighborhood Hits	213	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

SIM1_HUMAN
θ value	1.6852e-22 (rank : 15)	NC score	0.729196 (rank : 15)
Query Neighborhood Hits	213	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	1.6852e-22 (rank : 16)	NC score	0.728266 (rank : 16)
Query Neighborhood Hits	213	Target Neighborhood Hits	69	Shared Neighborhood Hits	43
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_MOUSE
θ value	1.42661e-21 (rank : 17)	NC score	0.723508 (rank : 18)
Query Neighborhood Hits	213	Target Neighborhood Hits	75	Shared Neighborhood Hits	43
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SIM2_HUMAN
θ value	3.17815e-21 (rank : 18)	NC score	0.724561 (rank : 17)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

NPAS3_MOUSE
θ value	2.5182e-18 (rank : 19)	NC score	0.688880 (rank : 19)
Query Neighborhood Hits	213	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
θ value	1.63225e-17 (rank : 20)	NC score	0.682043 (rank : 20)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NCOA1_MOUSE
θ value	2.43908e-13 (rank : 21)	NC score	0.590805 (rank : 25)
Query Neighborhood Hits	213	Target Neighborhood Hits	196	Shared Neighborhood Hits	58
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
θ value	4.16044e-13 (rank : 22)	NC score	0.586688 (rank : 26)
Query Neighborhood Hits	213	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA3_HUMAN
θ value	4.16044e-13 (rank : 23)	NC score	0.555782 (rank : 27)
Query Neighborhood Hits	213	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

PER3_HUMAN
θ value	2.69671e-12 (rank : 24)	NC score	0.456994 (rank : 37)
Query Neighborhood Hits	213	Target Neighborhood Hits	479	Shared Neighborhood Hits	68
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER1_MOUSE
θ value	4.59992e-12 (rank : 25)	NC score	0.463075 (rank : 36)
Query Neighborhood Hits	213	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER1_HUMAN
θ value	6.00763e-12 (rank : 26)	NC score	0.466021 (rank : 35)
Query Neighborhood Hits	213	Target Neighborhood Hits	215	Shared Neighborhood Hits	42
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

NPAS1_MOUSE
θ value	3.89403e-11 (rank : 27)	NC score	0.662502 (rank : 21)
Query Neighborhood Hits	213	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NCOA3_MOUSE
θ value	8.67504e-11 (rank : 28)	NC score	0.517729 (rank : 29)
Query Neighborhood Hits	213	Target Neighborhood Hits	203	Shared Neighborhood Hits	46
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER2_HUMAN
θ value	1.133e-10 (rank : 29)	NC score	0.466771 (rank : 34)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	36
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

NPAS1_HUMAN
θ value	1.9326e-10 (rank : 30)	NC score	0.659219 (rank : 22)
Query Neighborhood Hits	213	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

PER3_MOUSE
θ value	2.52405e-10 (rank : 31)	NC score	0.477539 (rank : 33)
Query Neighborhood Hits	213	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_MOUSE
θ value	1.25267e-09 (rank : 32)	NC score	0.439796 (rank : 38)
Query Neighborhood Hits	213	Target Neighborhood Hits	325	Shared Neighborhood Hits	48
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

AHR_HUMAN
θ value	1.63604e-09 (rank : 33)	NC score	0.648789 (rank : 23)
Query Neighborhood Hits	213	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NPAS4_MOUSE
θ value	1.80886e-08 (rank : 34)	NC score	0.509251 (rank : 32)
Query Neighborhood Hits	213	Target Neighborhood Hits	245	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA2_MOUSE
θ value	4.0297e-08 (rank : 35)	NC score	0.509460 (rank : 31)
Query Neighborhood Hits	213	Target Neighborhood Hits	281	Shared Neighborhood Hits	47
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA2_HUMAN
θ value	8.97725e-08 (rank : 36)	NC score	0.510257 (rank : 30)
Query Neighborhood Hits	213	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

AHR_MOUSE
θ value	1.17247e-07 (rank : 37)	NC score	0.633881 (rank : 24)
Query Neighborhood Hits	213	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NPAS4_HUMAN
θ value	1.17247e-07 (rank : 38)	NC score	0.523713 (rank : 28)
Query Neighborhood Hits	213	Target Neighborhood Hits	214	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

TFE3_HUMAN
θ value	0.000158464 (rank : 39)	NC score	0.264010 (rank : 42)
Query Neighborhood Hits	213	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MYCL1_HUMAN
θ value	0.000270298 (rank : 40)	NC score	0.193988 (rank : 52)
Query Neighborhood Hits	213	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

USF1_HUMAN
θ value	0.000270298 (rank : 41)	NC score	0.273970 (rank : 40)
Query Neighborhood Hits	213	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.000270298 (rank : 42)	NC score	0.274151 (rank : 39)
Query Neighborhood Hits	213	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFEB_HUMAN
θ value	0.000461057 (rank : 43)	NC score	0.254243 (rank : 46)
Query Neighborhood Hits	213	Target Neighborhood Hits	111	Shared Neighborhood Hits	46
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.000461057 (rank : 44)	NC score	0.255152 (rank : 45)
Query Neighborhood Hits	213	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF2_HUMAN
θ value	0.000461057 (rank : 45)	NC score	0.265429 (rank : 41)
Query Neighborhood Hits	213	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

MITF_MOUSE
θ value	0.000602161 (rank : 46)	NC score	0.257365 (rank : 43)
Query Neighborhood Hits	213	Target Neighborhood Hits	115	Shared Neighborhood Hits	54
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MYCL1_MOUSE
θ value	0.000786445 (rank : 47)	NC score	0.199013 (rank : 51)
Query Neighborhood Hits	213	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

USF2_MOUSE
θ value	0.000786445 (rank : 48)	NC score	0.256665 (rank : 44)
Query Neighborhood Hits	213	Target Neighborhood Hits	173	Shared Neighborhood Hits	48
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MITF_HUMAN
θ value	0.00134147 (rank : 49)	NC score	0.251485 (rank : 47)
Query Neighborhood Hits	213	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLL3_MOUSE
θ value	0.00175202 (rank : 50)	NC score	0.057477 (rank : 91)
Query Neighborhood Hits	213	Target Neighborhood Hits	1399	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RFIP1_HUMAN
θ value	0.00175202 (rank : 51)	NC score	0.048648 (rank : 105)
Query Neighborhood Hits	213	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

FIGN_HUMAN
θ value	0.0113563 (rank : 52)	NC score	0.030515 (rank : 129)
Query Neighborhood Hits	213	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

HEY2_HUMAN
θ value	0.0113563 (rank : 53)	NC score	0.224806 (rank : 48)
Query Neighborhood Hits	213	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	0.0113563 (rank : 54)	NC score	0.221920 (rank : 49)
Query Neighborhood Hits	213	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

WNK1_HUMAN
θ value	0.0193708 (rank : 55)	NC score	0.010254 (rank : 191)
Query Neighborhood Hits	213	Target Neighborhood Hits	1158	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

HXA3_MOUSE
θ value	0.0252991 (rank : 56)	NC score	0.012937 (rank : 183)
Query Neighborhood Hits	213	Target Neighborhood Hits	558	Shared Neighborhood Hits	23
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

NCOA6_MOUSE
θ value	0.0252991 (rank : 57)	NC score	0.083013 (rank : 75)
Query Neighborhood Hits	213	Target Neighborhood Hits	1076	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NKX61_HUMAN
θ value	0.0252991 (rank : 58)	NC score	0.020515 (rank : 160)
Query Neighborhood Hits	213	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

MUC13_MOUSE
θ value	0.0330416 (rank : 59)	NC score	0.052144 (rank : 98)
Query Neighborhood Hits	213	Target Neighborhood Hits	447	Shared Neighborhood Hits	32
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

TARSH_HUMAN
θ value	0.0330416 (rank : 60)	NC score	0.057412 (rank : 92)
Query Neighborhood Hits	213	Target Neighborhood Hits	768	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MUC5B_HUMAN
θ value	0.0431538 (rank : 61)	NC score	0.036785 (rank : 119)
Query Neighborhood Hits	213	Target Neighborhood Hits	1020	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NUPL1_HUMAN
θ value	0.0431538 (rank : 62)	NC score	0.043132 (rank : 109)
Query Neighborhood Hits	213	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BVL2, O43160	Gene names	NUPL1, KIAA0410
Domain Architecture	No domain graphic available
Description	Nucleoporin p58/p45 (Nucleoporin-like 1).

NU153_HUMAN
θ value	0.0563607 (rank : 63)	NC score	0.060678 (rank : 85)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

PPRB_HUMAN
θ value	0.0563607 (rank : 64)	NC score	0.044460 (rank : 106)
Query Neighborhood Hits	213	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

MYC_HUMAN
θ value	0.0736092 (rank : 65)	NC score	0.132762 (rank : 65)
Query Neighborhood Hits	213	Target Neighborhood Hits	146	Shared Neighborhood Hits	39
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

SRBP1_HUMAN
θ value	0.0736092 (rank : 66)	NC score	0.169219 (rank : 57)
Query Neighborhood Hits	213	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

EP400_HUMAN
θ value	0.0961366 (rank : 67)	NC score	0.033588 (rank : 124)
Query Neighborhood Hits	213	Target Neighborhood Hits	556	Shared Neighborhood Hits	38
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FIGN_MOUSE
θ value	0.0961366 (rank : 68)	NC score	0.027910 (rank : 134)
Query Neighborhood Hits	213	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

LR37A_HUMAN
θ value	0.0961366 (rank : 69)	NC score	0.040497 (rank : 114)
Query Neighborhood Hits	213	Target Neighborhood Hits	720	Shared Neighborhood Hits	48
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

MYCN_HUMAN
θ value	0.0961366 (rank : 70)	NC score	0.135805 (rank : 62)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	34
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

SAPS1_MOUSE
θ value	0.0961366 (rank : 71)	NC score	0.022537 (rank : 153)
Query Neighborhood Hits	213	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

SRBS1_MOUSE
θ value	0.0961366 (rank : 72)	NC score	0.024254 (rank : 142)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MAD4_HUMAN
θ value	0.163984 (rank : 73)	NC score	0.131409 (rank : 68)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAX_MOUSE
θ value	0.163984 (rank : 74)	NC score	0.184764 (rank : 55)
Query Neighborhood Hits	213	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MUC7_HUMAN
θ value	0.163984 (rank : 75)	NC score	0.071421 (rank : 79)
Query Neighborhood Hits	213	Target Neighborhood Hits	538	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MYC_MOUSE
θ value	0.163984 (rank : 76)	NC score	0.131563 (rank : 67)
Query Neighborhood Hits	213	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

SRRM2_HUMAN
θ value	0.163984 (rank : 77)	NC score	0.054873 (rank : 96)
Query Neighborhood Hits	213	Target Neighborhood Hits	1296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ZIM10_HUMAN
θ value	0.163984 (rank : 78)	NC score	0.033861 (rank : 123)
Query Neighborhood Hits	213	Target Neighborhood Hits	577	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

HGS_HUMAN
θ value	0.21417 (rank : 79)	NC score	0.032315 (rank : 127)
Query Neighborhood Hits	213	Target Neighborhood Hits	517	Shared Neighborhood Hits	35
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MAP1B_MOUSE
θ value	0.21417 (rank : 80)	NC score	0.021834 (rank : 155)
Query Neighborhood Hits	213	Target Neighborhood Hits	977	Shared Neighborhood Hits	38
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MAX_HUMAN
θ value	0.21417 (rank : 81)	NC score	0.174494 (rank : 56)
Query Neighborhood Hits	213	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MYCN_MOUSE
θ value	0.21417 (rank : 82)	NC score	0.132797 (rank : 64)
Query Neighborhood Hits	213	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

SRRM2_MOUSE
θ value	0.21417 (rank : 83)	NC score	0.060093 (rank : 86)
Query Neighborhood Hits	213	Target Neighborhood Hits	1470	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TCFL5_HUMAN
θ value	0.21417 (rank : 84)	NC score	0.190103 (rank : 54)
Query Neighborhood Hits	213	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

HEY1_HUMAN
θ value	0.279714 (rank : 85)	NC score	0.192916 (rank : 53)
Query Neighborhood Hits	213	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	0.279714 (rank : 86)	NC score	0.200653 (rank : 50)
Query Neighborhood Hits	213	Target Neighborhood Hits	69	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

K0999_HUMAN
θ value	0.279714 (rank : 87)	NC score	0.002250 (rank : 210)
Query Neighborhood Hits	213	Target Neighborhood Hits	899	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

LDB3_HUMAN
θ value	0.279714 (rank : 88)	NC score	0.015930 (rank : 174)
Query Neighborhood Hits	213	Target Neighborhood Hits	497	Shared Neighborhood Hits	27
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

LMBL2_MOUSE
θ value	0.279714 (rank : 89)	NC score	0.021998 (rank : 154)
Query Neighborhood Hits	213	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P59178	Gene names	L3mbtl2
Domain Architecture
Description	Lethal(3)malignant brain tumor-like 2 protein (L(3)mbt-like 2 protein) (H-l(3)mbt-like protein).

BPTF_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.026748 (rank : 137)
Query Neighborhood Hits	213	Target Neighborhood Hits	786	Shared Neighborhood Hits	37
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CG1_HUMAN
θ value	0.365318 (rank : 91)	NC score	0.049861 (rank : 103)
Query Neighborhood Hits	213	Target Neighborhood Hits	222	Shared Neighborhood Hits	32
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

GTSE1_MOUSE
θ value	0.365318 (rank : 92)	NC score	0.036649 (rank : 120)
Query Neighborhood Hits	213	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

TCOF_MOUSE
θ value	0.365318 (rank : 93)	NC score	0.028203 (rank : 133)
Query Neighborhood Hits	213	Target Neighborhood Hits	471	Shared Neighborhood Hits	23
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

BHLH3_HUMAN
θ value	0.47712 (rank : 94)	NC score	0.134477 (rank : 63)
Query Neighborhood Hits	213	Target Neighborhood Hits	106	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	0.47712 (rank : 95)	NC score	0.132499 (rank : 66)
Query Neighborhood Hits	213	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

PO121_HUMAN
θ value	0.47712 (rank : 96)	NC score	0.044000 (rank : 108)
Query Neighborhood Hits	213	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

R3HD2_MOUSE
θ value	0.47712 (rank : 97)	NC score	0.044184 (rank : 107)
Query Neighborhood Hits	213	Target Neighborhood Hits	397	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

SRBP1_MOUSE
θ value	0.47712 (rank : 98)	NC score	0.151377 (rank : 60)
Query Neighborhood Hits	213	Target Neighborhood Hits	384	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TNIK_HUMAN
θ value	0.47712 (rank : 99)	NC score	0.000609 (rank : 215)
Query Neighborhood Hits	213	Target Neighborhood Hits	1570	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

BLNK_MOUSE
θ value	0.62314 (rank : 100)	NC score	0.022576 (rank : 152)
Query Neighborhood Hits	213	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

EP400_MOUSE
θ value	0.62314 (rank : 101)	NC score	0.029020 (rank : 131)
Query Neighborhood Hits	213	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

K0999_MOUSE
θ value	0.62314 (rank : 102)	NC score	0.001956 (rank : 211)
Query Neighborhood Hits	213	Target Neighborhood Hits	931	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

NU214_HUMAN
θ value	0.62314 (rank : 103)	NC score	0.050124 (rank : 102)
Query Neighborhood Hits	213	Target Neighborhood Hits	657	Shared Neighborhood Hits	56
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RUSC2_HUMAN
θ value	0.62314 (rank : 104)	NC score	0.023370 (rank : 150)
Query Neighborhood Hits	213	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SMG1_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.023999 (rank : 144)
Query Neighborhood Hits	213	Target Neighborhood Hits	231	Shared Neighborhood Hits	8
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

ZN326_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.025901 (rank : 139)
Query Neighborhood Hits	213	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

MYCS_MOUSE
θ value	0.813845 (rank : 107)	NC score	0.131277 (rank : 69)
Query Neighborhood Hits	213	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

NKX61_MOUSE
θ value	0.813845 (rank : 108)	NC score	0.015698 (rank : 177)
Query Neighborhood Hits	213	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NUP62_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.028758 (rank : 132)
Query Neighborhood Hits	213	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

PO6F2_MOUSE
θ value	0.813845 (rank : 110)	NC score	0.023501 (rank : 148)
Query Neighborhood Hits	213	Target Neighborhood Hits	639	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PODXL_HUMAN
θ value	0.813845 (rank : 111)	NC score	0.051360 (rank : 100)
Query Neighborhood Hits	213	Target Neighborhood Hits	191	Shared Neighborhood Hits	33
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RSNL2_HUMAN
θ value	0.813845 (rank : 112)	NC score	0.013497 (rank : 181)
Query Neighborhood Hits	213	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SC24B_HUMAN
θ value	0.813845 (rank : 113)	NC score	0.027304 (rank : 135)
Query Neighborhood Hits	213	Target Neighborhood Hits	108	Shared Neighborhood Hits	18
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SMG1_MOUSE
θ value	0.813845 (rank : 114)	NC score	0.024383 (rank : 141)
Query Neighborhood Hits	213	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SRBP2_HUMAN
θ value	0.813845 (rank : 115)	NC score	0.138344 (rank : 61)
Query Neighborhood Hits	213	Target Neighborhood Hits	133	Shared Neighborhood Hits	51
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

SYNE1_HUMAN
θ value	0.813845 (rank : 116)	NC score	0.003178 (rank : 207)
Query Neighborhood Hits	213	Target Neighborhood Hits	1484	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

BSN_MOUSE
θ value	1.06291 (rank : 117)	NC score	0.050495 (rank : 101)
Query Neighborhood Hits	213	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

GRIN1_MOUSE
θ value	1.06291 (rank : 118)	NC score	0.032880 (rank : 125)
Query Neighborhood Hits	213	Target Neighborhood Hits	337	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MAGE1_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.042901 (rank : 110)
Query Neighborhood Hits	213	Target Neighborhood Hits	1389	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MLL3_HUMAN
θ value	1.06291 (rank : 120)	NC score	0.057239 (rank : 93)
Query Neighborhood Hits	213	Target Neighborhood Hits	1644	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCLO_MOUSE
θ value	1.06291 (rank : 121)	NC score	0.032670 (rank : 126)
Query Neighborhood Hits	213	Target Neighborhood Hits	2275	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RBM14_MOUSE
θ value	1.06291 (rank : 122)	NC score	0.014403 (rank : 179)
Query Neighborhood Hits	213	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

SC24C_HUMAN
θ value	1.06291 (rank : 123)	NC score	0.036551 (rank : 121)
Query Neighborhood Hits	213	Target Neighborhood Hits	662	Shared Neighborhood Hits	52
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

BHLH2_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.125000 (rank : 70)
Query Neighborhood Hits	213	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	1.38821 (rank : 125)	NC score	0.124367 (rank : 71)
Query Neighborhood Hits	213	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

EP300_HUMAN
θ value	1.38821 (rank : 126)	NC score	0.038704 (rank : 116)
Query Neighborhood Hits	213	Target Neighborhood Hits	821	Shared Neighborhood Hits	56
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

HCN4_HUMAN
θ value	1.38821 (rank : 127)	NC score	0.015802 (rank : 175)
Query Neighborhood Hits	213	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HES4_HUMAN
θ value	1.38821 (rank : 128)	NC score	0.098514 (rank : 72)
Query Neighborhood Hits	213	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

PF21B_MOUSE
θ value	1.38821 (rank : 129)	NC score	0.030933 (rank : 128)
Query Neighborhood Hits	213	Target Neighborhood Hits	278	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PO6F2_HUMAN
θ value	1.38821 (rank : 130)	NC score	0.021757 (rank : 157)
Query Neighborhood Hits	213	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

TIEG3_MOUSE
θ value	1.38821 (rank : 131)	NC score	-0.000688 (rank : 218)
Query Neighborhood Hits	213	Target Neighborhood Hits	774	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

UBP2L_MOUSE
θ value	1.38821 (rank : 132)	NC score	0.039726 (rank : 115)
Query Neighborhood Hits	213	Target Neighborhood Hits	173	Shared Neighborhood Hits	22
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

NUPL_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.020780 (rank : 159)
Query Neighborhood Hits	213	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

UBR2_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.023596 (rank : 147)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

UBR2_MOUSE
θ value	1.81305 (rank : 135)	NC score	0.023680 (rank : 145)
Query Neighborhood Hits	213	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

ATN1_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.042594 (rank : 111)
Query Neighborhood Hits	213	Target Neighborhood Hits	676	Shared Neighborhood Hits	49
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

MILK1_HUMAN
θ value	2.36792 (rank : 137)	NC score	0.018478 (rank : 164)
Query Neighborhood Hits	213	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MINT_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.021815 (rank : 156)
Query Neighborhood Hits	213	Target Neighborhood Hits	1291	Shared Neighborhood Hits	56
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SRF_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.023427 (rank : 149)
Query Neighborhood Hits	213	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	P11831	Gene names	SRF
Domain Architecture
Description	Serum response factor (SRF).

TFE2_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.012980 (rank : 182)
Query Neighborhood Hits	213	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

WBS14_MOUSE
θ value	2.36792 (rank : 141)	NC score	0.037623 (rank : 118)
Query Neighborhood Hits	213	Target Neighborhood Hits	171	Shared Neighborhood Hits	27
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZIM10_MOUSE
θ value	2.36792 (rank : 142)	NC score	0.027282 (rank : 136)
Query Neighborhood Hits	213	Target Neighborhood Hits	430	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

ZN326_MOUSE
θ value	2.36792 (rank : 143)	NC score	0.021558 (rank : 158)
Query Neighborhood Hits	213	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

AP180_HUMAN
θ value	3.0926 (rank : 144)	NC score	0.020107 (rank : 162)
Query Neighborhood Hits	213	Target Neighborhood Hits	183	Shared Neighborhood Hits	21
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

B4GN3_MOUSE
θ value	3.0926 (rank : 145)	NC score	0.010101 (rank : 192)
Query Neighborhood Hits	213	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

COE3_MOUSE
θ value	3.0926 (rank : 146)	NC score	0.011109 (rank : 188)
Query Neighborhood Hits	213	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

FARP2_MOUSE
θ value	3.0926 (rank : 147)	NC score	0.003282 (rank : 205)
Query Neighborhood Hits	213	Target Neighborhood Hits	209	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

GAK_MOUSE
θ value	3.0926 (rank : 148)	NC score	0.001258 (rank : 212)
Query Neighborhood Hits	213	Target Neighborhood Hits	964	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

MAML1_MOUSE
θ value	3.0926 (rank : 149)	NC score	0.034377 (rank : 122)
Query Neighborhood Hits	213	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

NRDC_MOUSE
θ value	3.0926 (rank : 150)	NC score	0.020413 (rank : 161)
Query Neighborhood Hits	213	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

NUPL_MOUSE
θ value	3.0926 (rank : 151)	NC score	0.026519 (rank : 138)
Query Neighborhood Hits	213	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

PO121_MOUSE
θ value	3.0926 (rank : 152)	NC score	0.040562 (rank : 113)
Query Neighborhood Hits	213	Target Neighborhood Hits	345	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

RXRA_MOUSE
θ value	3.0926 (rank : 153)	NC score	0.002564 (rank : 209)
Query Neighborhood Hits	213	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

SETB1_HUMAN
θ value	3.0926 (rank : 154)	NC score	0.014487 (rank : 178)
Query Neighborhood Hits	213	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SMAP1_HUMAN
θ value	3.0926 (rank : 155)	NC score	0.012470 (rank : 184)
Query Neighborhood Hits	213	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SRF_MOUSE
θ value	3.0926 (rank : 156)	NC score	0.022812 (rank : 151)
Query Neighborhood Hits	213	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JM73	Gene names	Srf
Domain Architecture	No domain graphic available
Description	Serum response factor (SRF).

TAF6_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.018135 (rank : 166)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

UBP2L_HUMAN
θ value	3.0926 (rank : 158)	NC score	0.037715 (rank : 117)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

WNK1_MOUSE
θ value	3.0926 (rank : 159)	NC score	0.010582 (rank : 189)
Query Neighborhood Hits	213	Target Neighborhood Hits	1179	Shared Neighborhood Hits	53
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

LR37B_HUMAN
θ value	4.03905 (rank : 160)	NC score	0.017470 (rank : 168)
Query Neighborhood Hits	213	Target Neighborhood Hits	392	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

LTBP2_HUMAN
θ value	4.03905 (rank : 161)	NC score	0.003186 (rank : 206)
Query Neighborhood Hits	213	Target Neighborhood Hits	552	Shared Neighborhood Hits	17
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MSH4_MOUSE
θ value	4.03905 (rank : 162)	NC score	0.008611 (rank : 196)
Query Neighborhood Hits	213	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

RBM14_HUMAN
θ value	4.03905 (rank : 163)	NC score	0.011444 (rank : 186)
Query Neighborhood Hits	213	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

TAF3_HUMAN
θ value	4.03905 (rank : 164)	NC score	0.017554 (rank : 167)
Query Neighborhood Hits	213	Target Neighborhood Hits	568	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TARA_HUMAN
θ value	4.03905 (rank : 165)	NC score	0.041822 (rank : 112)
Query Neighborhood Hits	213	Target Neighborhood Hits	1626	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRIO_HUMAN
θ value	4.03905 (rank : 166)	NC score	-0.000283 (rank : 217)
Query Neighborhood Hits	213	Target Neighborhood Hits	1580	Shared Neighborhood Hits	26
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TTC28_HUMAN
θ value	4.03905 (rank : 167)	NC score	0.011686 (rank : 185)
Query Neighborhood Hits	213	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

XRN1_MOUSE
θ value	4.03905 (rank : 168)	NC score	0.009829 (rank : 193)
Query Neighborhood Hits	213	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

ZN516_HUMAN
θ value	4.03905 (rank : 169)	NC score	-0.003052 (rank : 225)
Query Neighborhood Hits	213	Target Neighborhood Hits	854	Shared Neighborhood Hits	21
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

ADRM1_HUMAN
θ value	5.27518 (rank : 170)	NC score	0.016922 (rank : 170)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

BSN_HUMAN
θ value	5.27518 (rank : 171)	NC score	0.051957 (rank : 99)
Query Neighborhood Hits	213	Target Neighborhood Hits	1537	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CAC1E_HUMAN
θ value	5.27518 (rank : 172)	NC score	0.002932 (rank : 208)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

CEND3_HUMAN
θ value	5.27518 (rank : 173)	NC score	0.006070 (rank : 203)
Query Neighborhood Hits	213	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

COE3_HUMAN
θ value	5.27518 (rank : 174)	NC score	0.011255 (rank : 187)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

CTTB2_HUMAN
θ value	5.27518 (rank : 175)	NC score	0.000463 (rank : 216)
Query Neighborhood Hits	213	Target Neighborhood Hits	1061	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DDEF2_MOUSE
θ value	5.27518 (rank : 176)	NC score	0.008358 (rank : 197)
Query Neighborhood Hits	213	Target Neighborhood Hits	625	Shared Neighborhood Hits	22
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DTX2_MOUSE
θ value	5.27518 (rank : 177)	NC score	0.007490 (rank : 198)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

ELF4_HUMAN
θ value	5.27518 (rank : 178)	NC score	0.006453 (rank : 200)
Query Neighborhood Hits	213	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

EYA3_HUMAN
θ value	5.27518 (rank : 179)	NC score	0.006401 (rank : 201)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

FGRL1_MOUSE
θ value	5.27518 (rank : 180)	NC score	0.001227 (rank : 213)
Query Neighborhood Hits	213	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

HCN4_MOUSE
θ value	5.27518 (rank : 181)	NC score	0.015945 (rank : 173)
Query Neighborhood Hits	213	Target Neighborhood Hits	284	Shared Neighborhood Hits	23
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MAD1_HUMAN
θ value	5.27518 (rank : 182)	NC score	0.048879 (rank : 104)
Query Neighborhood Hits	213	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MLX_MOUSE
θ value	5.27518 (rank : 183)	NC score	0.166800 (rank : 58)
Query Neighborhood Hits	213	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

NCA11_MOUSE
θ value	5.27518 (rank : 184)	NC score	0.003979 (rank : 204)
Query Neighborhood Hits	213	Target Neighborhood Hits	661	Shared Neighborhood Hits	27
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

ODBA_MOUSE
θ value	5.27518 (rank : 185)	NC score	0.009462 (rank : 194)
Query Neighborhood Hits	213	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P50136	Gene names	Bckdha
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha).

MAD1_MOUSE
θ value	6.88961 (rank : 186)	NC score	0.058467 (rank : 89)
Query Neighborhood Hits	213	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MAD3_HUMAN
θ value	6.88961 (rank : 187)	NC score	0.078608 (rank : 76)
Query Neighborhood Hits	213	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MLX_HUMAN
θ value	6.88961 (rank : 188)	NC score	0.160892 (rank : 59)
Query Neighborhood Hits	213	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MYCL2_HUMAN
θ value	6.88961 (rank : 189)	NC score	0.089262 (rank : 74)
Query Neighborhood Hits	213	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

NFRKB_HUMAN
θ value	6.88961 (rank : 190)	NC score	0.017210 (rank : 169)
Query Neighborhood Hits	213	Target Neighborhood Hits	211	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PFTK1_MOUSE
θ value	6.88961 (rank : 191)	NC score	-0.002663 (rank : 223)
Query Neighborhood Hits	213	Target Neighborhood Hits	835	Shared Neighborhood Hits	11
SwissProt Accessions	O35495, O35848	Gene names	Pftk1
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

PHLB1_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.015772 (rank : 176)
Query Neighborhood Hits	213	Target Neighborhood Hits	1038	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RANB3_MOUSE
θ value	6.88961 (rank : 193)	NC score	0.016617 (rank : 171)
Query Neighborhood Hits	213	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

RAPH1_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.025865 (rank : 140)
Query Neighborhood Hits	213	Target Neighborhood Hits	593	Shared Neighborhood Hits	38
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SDC3_MOUSE
θ value	6.88961 (rank : 195)	NC score	0.024015 (rank : 143)
Query Neighborhood Hits	213	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SFPQ_HUMAN
θ value	6.88961 (rank : 196)	NC score	0.018866 (rank : 163)
Query Neighborhood Hits	213	Target Neighborhood Hits	986	Shared Neighborhood Hits	44
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

ACK1_HUMAN
θ value	8.99809 (rank : 197)	NC score	-0.001149 (rank : 221)
Query Neighborhood Hits	213	Target Neighborhood Hits	1140	Shared Neighborhood Hits	33
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

CCAR1_HUMAN
θ value	8.99809 (rank : 198)	NC score	0.009106 (rank : 195)
Query Neighborhood Hits	213	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CJ006_HUMAN
θ value	8.99809 (rank : 199)	NC score	0.006288 (rank : 202)
Query Neighborhood Hits	213	Target Neighborhood Hits	122	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

ENAH_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.023628 (rank : 146)
Query Neighborhood Hits	213	Target Neighborhood Hits	919	Shared Neighborhood Hits	37
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FHOD1_HUMAN
θ value	8.99809 (rank : 201)	NC score	0.014265 (rank : 180)
Query Neighborhood Hits	213	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FHOD1_MOUSE
θ value	8.99809 (rank : 202)	NC score	0.016076 (rank : 172)
Query Neighborhood Hits	213	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

IF4G1_HUMAN
θ value	8.99809 (rank : 203)	NC score	0.007261 (rank : 199)
Query Neighborhood Hits	213	Target Neighborhood Hits	347	Shared Neighborhood Hits	17
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

LAMC3_MOUSE
θ value	8.99809 (rank : 204)	NC score	-0.000845 (rank : 220)
Query Neighborhood Hits	213	Target Neighborhood Hits	624	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTB1L_MOUSE
θ value	8.99809 (rank : 205)	NC score	0.000742 (rank : 214)
Query Neighborhood Hits	213	Target Neighborhood Hits	514	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

MCM3A_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.010396 (rank : 190)
Query Neighborhood Hits	213	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

MINK1_MOUSE
θ value	8.99809 (rank : 207)	NC score	-0.000729 (rank : 219)
Query Neighborhood Hits	213	Target Neighborhood Hits	1451	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

NUMBL_HUMAN
θ value	8.99809 (rank : 208)	NC score	0.018445 (rank : 165)
Query Neighborhood Hits	213	Target Neighborhood Hits	394	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

PRG4_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.029201 (rank : 130)
Query Neighborhood Hits	213	Target Neighborhood Hits	764	Shared Neighborhood Hits	42
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SP2_HUMAN
θ value	8.99809 (rank : 210)	NC score	-0.003650 (rank : 227)
Query Neighborhood Hits	213	Target Neighborhood Hits	747	Shared Neighborhood Hits	14
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.

SP4_HUMAN
θ value	8.99809 (rank : 211)	NC score	-0.002921 (rank : 224)
Query Neighborhood Hits	213	Target Neighborhood Hits	749	Shared Neighborhood Hits	17
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

SP4_MOUSE
θ value	8.99809 (rank : 212)	NC score	-0.003153 (rank : 226)
Query Neighborhood Hits	213	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

ZBTB4_HUMAN
θ value	8.99809 (rank : 213)	NC score	-0.001602 (rank : 222)
Query Neighborhood Hits	213	Target Neighborhood Hits	926	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

HES1_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.075333 (rank : 78)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.076143 (rank : 77)
Query Neighborhood Hits	213	Target Neighborhood Hits	78	Shared Neighborhood Hits	34
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES3_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.064924 (rank : 83)
Query Neighborhood Hits	213	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

HES5_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.092254 (rank : 73)
Query Neighborhood Hits	213	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

HES7_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.062167 (rank : 84)
Query Neighborhood Hits	213	Target Neighborhood Hits	72	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.059454 (rank : 87)
Query Neighborhood Hits	213	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MAD3_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.055509 (rank : 94)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	29
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD4_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.054888 (rank : 95)
Query Neighborhood Hits	213	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MNT_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.070986 (rank : 80)
Query Neighborhood Hits	213	Target Neighborhood Hits	496	Shared Neighborhood Hits	57
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.069487 (rank : 82)
Query Neighborhood Hits	213	Target Neighborhood Hits	432	Shared Neighborhood Hits	55
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MXI1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.058172 (rank : 90)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.059132 (rank : 88)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

NCOA6_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.069734 (rank : 81)
Query Neighborhood Hits	213	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SON_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.052339 (rank : 97)
Query Neighborhood Hits	213	Target Neighborhood Hits	1568	Shared Neighborhood Hits	103
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

Hits sorted by NC score

ARNT_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	213	Target Neighborhood Hits	213	Shared Neighborhood Hits	213
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_HUMAN
NC score	0.983049 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	86
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT2_HUMAN
NC score	0.973755 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	80
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
NC score	0.972909 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	213	Target Neighborhood Hits	115	Shared Neighborhood Hits	80
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

BMAL1_HUMAN
NC score	0.924801 (rank : 5)	θ value	4.65103e-89 (rank : 6)
Query Neighborhood Hits	213	Target Neighborhood Hits	115	Shared Neighborhood Hits	70
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.922969 (rank : 6)	θ value	2.08775e-89 (rank : 5)
Query Neighborhood Hits	213	Target Neighborhood Hits	121	Shared Neighborhood Hits	70
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

CLOCK_MOUSE
NC score	0.795993 (rank : 7)	θ value	4.42448e-31 (rank : 8)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	66
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.795021 (rank : 8)	θ value	1.28732e-30 (rank : 9)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	65
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

NPAS2_HUMAN
NC score	0.794288 (rank : 9)	θ value	8.91499e-32 (rank : 7)
Query Neighborhood Hits	213	Target Neighborhood Hits	150	Shared Neighborhood Hits	66
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
NC score	0.794218 (rank : 10)	θ value	2.19584e-30 (rank : 10)
Query Neighborhood Hits	213	Target Neighborhood Hits	132	Shared Neighborhood Hits	67
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

EPAS1_MOUSE
NC score	0.775106 (rank : 11)	θ value	8.3442e-30 (rank : 11)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	40
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
NC score	0.774905 (rank : 12)	θ value	1.08979e-29 (rank : 12)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	39
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

HIF1A_HUMAN
NC score	0.762996 (rank : 13)	θ value	5.06226e-27 (rank : 13)
Query Neighborhood Hits	213	Target Neighborhood Hits	118	Shared Neighborhood Hits	47
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
NC score	0.762959 (rank : 14)	θ value	1.47289e-26 (rank : 14)
Query Neighborhood Hits	213	Target Neighborhood Hits	90	Shared Neighborhood Hits	42
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

SIM1_HUMAN
NC score	0.729196 (rank : 15)	θ value	1.6852e-22 (rank : 15)
Query Neighborhood Hits	213	Target Neighborhood Hits	62	Shared Neighborhood Hits	42
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
NC score	0.728266 (rank : 16)	θ value	1.6852e-22 (rank : 16)
Query Neighborhood Hits	213	Target Neighborhood Hits	69	Shared Neighborhood Hits	43
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_HUMAN
NC score	0.724561 (rank : 17)	θ value	3.17815e-21 (rank : 18)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
NC score	0.723508 (rank : 18)	θ value	1.42661e-21 (rank : 17)
Query Neighborhood Hits	213	Target Neighborhood Hits	75	Shared Neighborhood Hits	43
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

NPAS3_MOUSE
NC score	0.688880 (rank : 19)	θ value	2.5182e-18 (rank : 19)
Query Neighborhood Hits	213	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
NC score	0.682043 (rank : 20)	θ value	1.63225e-17 (rank : 20)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_MOUSE
NC score	0.662502 (rank : 21)	θ value	3.89403e-11 (rank : 27)
Query Neighborhood Hits	213	Target Neighborhood Hits	63	Shared Neighborhood Hits	33
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.659219 (rank : 22)	θ value	1.9326e-10 (rank : 30)
Query Neighborhood Hits	213	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

AHR_HUMAN
NC score	0.648789 (rank : 23)	θ value	1.63604e-09 (rank : 33)
Query Neighborhood Hits	213	Target Neighborhood Hits	47	Shared Neighborhood Hits	35
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.633881 (rank : 24)	θ value	1.17247e-07 (rank : 37)
Query Neighborhood Hits	213	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NCOA1_MOUSE
NC score	0.590805 (rank : 25)	θ value	2.43908e-13 (rank : 21)
Query Neighborhood Hits	213	Target Neighborhood Hits	196	Shared Neighborhood Hits	58
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.586688 (rank : 26)	θ value	4.16044e-13 (rank : 22)
Query Neighborhood Hits	213	Target Neighborhood Hits	198	Shared Neighborhood Hits	56
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA3_HUMAN
NC score	0.555782 (rank : 27)	θ value	4.16044e-13 (rank : 23)
Query Neighborhood Hits	213	Target Neighborhood Hits	171	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NPAS4_HUMAN
NC score	0.523713 (rank : 28)	θ value	1.17247e-07 (rank : 38)
Query Neighborhood Hits	213	Target Neighborhood Hits	214	Shared Neighborhood Hits	61
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NCOA3_MOUSE
NC score	0.517729 (rank : 29)	θ value	8.67504e-11 (rank : 28)
Query Neighborhood Hits	213	Target Neighborhood Hits	203	Shared Neighborhood Hits	46
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NCOA2_HUMAN
NC score	0.510257 (rank : 30)	θ value	8.97725e-08 (rank : 36)
Query Neighborhood Hits	213	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
NC score	0.509460 (rank : 31)	θ value	4.0297e-08 (rank : 35)
Query Neighborhood Hits	213	Target Neighborhood Hits	281	Shared Neighborhood Hits	47
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NPAS4_MOUSE
NC score	0.509251 (rank : 32)	θ value	1.80886e-08 (rank : 34)
Query Neighborhood Hits	213	Target Neighborhood Hits	245	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PER3_MOUSE
NC score	0.477539 (rank : 33)	θ value	2.52405e-10 (rank : 31)
Query Neighborhood Hits	213	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_HUMAN
NC score	0.466771 (rank : 34)	θ value	1.133e-10 (rank : 29)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	36
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_HUMAN
NC score	0.466021 (rank : 35)	θ value	6.00763e-12 (rank : 26)
Query Neighborhood Hits	213	Target Neighborhood Hits	215	Shared Neighborhood Hits	42
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.463075 (rank : 36)	θ value	4.59992e-12 (rank : 25)
Query Neighborhood Hits	213	Target Neighborhood Hits	235	Shared Neighborhood Hits	45
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
NC score	0.456994 (rank : 37)	θ value	2.69671e-12 (rank : 24)
Query Neighborhood Hits	213	Target Neighborhood Hits	479	Shared Neighborhood Hits	68
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
NC score	0.439796 (rank : 38)	θ value	1.25267e-09 (rank : 32)
Query Neighborhood Hits	213	Target Neighborhood Hits	325	Shared Neighborhood Hits	48
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

USF1_MOUSE
NC score	0.274151 (rank : 39)	θ value	0.000270298 (rank : 42)
Query Neighborhood Hits	213	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.273970 (rank : 40)	θ value	0.000270298 (rank : 41)
Query Neighborhood Hits	213	Target Neighborhood Hits	70	Shared Neighborhood Hits	45
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.265429 (rank : 41)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	213	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

TFE3_HUMAN
NC score	0.264010 (rank : 42)	θ value	0.000158464 (rank : 39)
Query Neighborhood Hits	213	Target Neighborhood Hits	190	Shared Neighborhood Hits	52
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_MOUSE
NC score	0.257365 (rank : 43)	θ value	0.000602161 (rank : 46)
Query Neighborhood Hits	213	Target Neighborhood Hits	115	Shared Neighborhood Hits	54
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

USF2_MOUSE
NC score	0.256665 (rank : 44)	θ value	0.000786445 (rank : 48)
Query Neighborhood Hits	213	Target Neighborhood Hits	173	Shared Neighborhood Hits	48
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

TFEB_MOUSE
NC score	0.255152 (rank : 45)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	213	Target Neighborhood Hits	119	Shared Neighborhood Hits	49
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.254243 (rank : 46)	θ value	0.000461057 (rank : 43)
Query Neighborhood Hits	213	Target Neighborhood Hits	111	Shared Neighborhood Hits	46
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MITF_HUMAN
NC score	0.251485 (rank : 47)	θ value	0.00134147 (rank : 49)
Query Neighborhood Hits	213	Target Neighborhood Hits	113	Shared Neighborhood Hits	55
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

HEY2_HUMAN
NC score	0.224806 (rank : 48)	θ value	0.0113563 (rank : 53)
Query Neighborhood Hits	213	Target Neighborhood Hits	77	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.221920 (rank : 49)	θ value	0.0113563 (rank : 54)
Query Neighborhood Hits	213	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.200653 (rank : 50)	θ value	0.279714 (rank : 86)
Query Neighborhood Hits	213	Target Neighborhood Hits	69	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

MYCL1_MOUSE
NC score	0.199013 (rank : 51)	θ value	0.000786445 (rank : 47)
Query Neighborhood Hits	213	Target Neighborhood Hits	123	Shared Neighborhood Hits	42
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_HUMAN
NC score	0.193988 (rank : 52)	θ value	0.000270298 (rank : 40)
Query Neighborhood Hits	213	Target Neighborhood Hits	146	Shared Neighborhood Hits	42
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

HEY1_HUMAN
NC score	0.192916 (rank : 53)	θ value	0.279714 (rank : 85)
Query Neighborhood Hits	213	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

TCFL5_HUMAN
NC score	0.190103 (rank : 54)	θ value	0.21417 (rank : 84)
Query Neighborhood Hits	213	Target Neighborhood Hits	43	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

MAX_MOUSE
NC score	0.184764 (rank : 55)	θ value	0.163984 (rank : 74)
Query Neighborhood Hits	213	Target Neighborhood Hits	139	Shared Neighborhood Hits	41
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MAX_HUMAN
NC score	0.174494 (rank : 56)	θ value	0.21417 (rank : 81)
Query Neighborhood Hits	213	Target Neighborhood Hits	125	Shared Neighborhood Hits	40
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

SRBP1_HUMAN
NC score	0.169219 (rank : 57)	θ value	0.0736092 (rank : 66)
Query Neighborhood Hits	213	Target Neighborhood Hits	225	Shared Neighborhood Hits	60
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MLX_MOUSE
NC score	0.166800 (rank : 58)	θ value	5.27518 (rank : 183)
Query Neighborhood Hits	213	Target Neighborhood Hits	100	Shared Neighborhood Hits	44
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.160892 (rank : 59)	θ value	6.88961 (rank : 188)
Query Neighborhood Hits	213	Target Neighborhood Hits	95	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

SRBP1_MOUSE
NC score	0.151377 (rank : 60)	θ value	0.47712 (rank : 98)
Query Neighborhood Hits	213	Target Neighborhood Hits	384	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
NC score	0.138344 (rank : 61)	θ value	0.813845 (rank : 115)
Query Neighborhood Hits	213	Target Neighborhood Hits	133	Shared Neighborhood Hits	51
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MYCN_HUMAN
NC score	0.135805 (rank : 62)	θ value	0.0961366 (rank : 70)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	34
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

BHLH3_HUMAN
NC score	0.134477 (rank : 63)	θ value	0.47712 (rank : 94)
Query Neighborhood Hits	213	Target Neighborhood Hits	106	Shared Neighborhood Hits	41
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

MYCN_MOUSE
NC score	0.132797 (rank : 64)	θ value	0.21417 (rank : 82)
Query Neighborhood Hits	213	Target Neighborhood Hits	125	Shared Neighborhood Hits	36
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYC_HUMAN
NC score	0.132762 (rank : 65)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	213	Target Neighborhood Hits	146	Shared Neighborhood Hits	39
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

BHLH3_MOUSE
NC score	0.132499 (rank : 66)	θ value	0.47712 (rank : 95)
Query Neighborhood Hits	213	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

MYC_MOUSE
NC score	0.131563 (rank : 67)	θ value	0.163984 (rank : 76)
Query Neighborhood Hits	213	Target Neighborhood Hits	125	Shared Neighborhood Hits	32
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MAD4_HUMAN
NC score	0.131409 (rank : 68)	θ value	0.163984 (rank : 73)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MYCS_MOUSE
NC score	0.131277 (rank : 69)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	213	Target Neighborhood Hits	83	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

BHLH2_HUMAN
NC score	0.125000 (rank : 70)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	213	Target Neighborhood Hits	80	Shared Neighborhood Hits	43
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
NC score	0.124367 (rank : 71)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	213	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

HES4_HUMAN
NC score	0.098514 (rank : 72)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	213	Target Neighborhood Hits	58	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HES5_MOUSE
NC score	0.092254 (rank : 73)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	213	Target Neighborhood Hits	38	Shared Neighborhood Hits	25
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

MYCL2_HUMAN
NC score	0.089262 (rank : 74)	θ value	6.88961 (rank : 189)
Query Neighborhood Hits	213	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

NCOA6_MOUSE
NC score	0.083013 (rank : 75)	θ value	0.0252991 (rank : 57)
Query Neighborhood Hits	213	Target Neighborhood Hits	1076	Shared Neighborhood Hits	92
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MAD3_HUMAN
NC score	0.078608 (rank : 76)	θ value	6.88961 (rank : 187)
Query Neighborhood Hits	213	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

HES1_MOUSE
NC score	0.076143 (rank : 77)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	213	Target Neighborhood Hits	78	Shared Neighborhood Hits	34
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.075333 (rank : 78)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	31
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

MUC7_HUMAN
NC score	0.071421 (rank : 79)	θ value	0.163984 (rank : 75)
Query Neighborhood Hits	213	Target Neighborhood Hits	538	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

MNT_HUMAN
NC score	0.070986 (rank : 80)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	213	Target Neighborhood Hits	496	Shared Neighborhood Hits	57
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NCOA6_HUMAN
NC score	0.069734 (rank : 81)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	213	Target Neighborhood Hits	1202	Shared Neighborhood Hits	94
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MNT_MOUSE
NC score	0.069487 (rank : 82)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	213	Target Neighborhood Hits	432	Shared Neighborhood Hits	55
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

HES3_MOUSE
NC score	0.064924 (rank : 83)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	213	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

HES7_HUMAN
NC score	0.062167 (rank : 84)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	213	Target Neighborhood Hits	72	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

NU153_HUMAN
NC score	0.060678 (rank : 85)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	213	Target Neighborhood Hits	227	Shared Neighborhood Hits	31
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

SRRM2_MOUSE
NC score	0.060093 (rank : 86)	θ value	0.21417 (rank : 83)
Query Neighborhood Hits	213	Target Neighborhood Hits	1470	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

HES7_MOUSE
NC score	0.059454 (rank : 87)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	213	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MXI1_MOUSE
NC score	0.059132 (rank : 88)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	213	Target Neighborhood Hits	109	Shared Neighborhood Hits	35
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MAD1_MOUSE
NC score	0.058467 (rank : 89)	θ value	6.88961 (rank : 186)
Query Neighborhood Hits	213	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MXI1_HUMAN
NC score	0.058172 (rank : 90)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	34
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MLL3_MOUSE
NC score	0.057477 (rank : 91)	θ value	0.00175202 (rank : 50)
Query Neighborhood Hits	213	Target Neighborhood Hits	1399	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TARSH_HUMAN
NC score	0.057412 (rank : 92)	θ value	0.0330416 (rank : 60)
Query Neighborhood Hits	213	Target Neighborhood Hits	768	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MLL3_HUMAN
NC score	0.057239 (rank : 93)	θ value	1.06291 (rank : 120)
Query Neighborhood Hits	213	Target Neighborhood Hits	1644	Shared Neighborhood Hits	88
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MAD3_MOUSE
NC score	0.055509 (rank : 94)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	213	Target Neighborhood Hits	94	Shared Neighborhood Hits	29
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD4_MOUSE
NC score	0.054888 (rank : 95)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	213	Target Neighborhood Hits	65	Shared Neighborhood Hits	26
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

SRRM2_HUMAN
NC score	0.054873 (rank : 96)	θ value	0.163984 (rank : 77)
Query Neighborhood Hits	213	Target Neighborhood Hits	1296	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SON_HUMAN
NC score	0.052339 (rank : 97)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	213	Target Neighborhood Hits	1568	Shared Neighborhood Hits	103
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

MUC13_MOUSE
NC score	0.052144 (rank : 98)	θ value	0.0330416 (rank : 59)
Query Neighborhood Hits	213	Target Neighborhood Hits	447	Shared Neighborhood Hits	32
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

BSN_HUMAN
NC score	0.051957 (rank : 99)	θ value	5.27518 (rank : 171)
Query Neighborhood Hits	213	Target Neighborhood Hits	1537	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PODXL_HUMAN
NC score	0.051360 (rank : 100)	θ value	0.813845 (rank : 111)
Query Neighborhood Hits	213	Target Neighborhood Hits	191	Shared Neighborhood Hits	33
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

BSN_MOUSE
NC score	0.050495 (rank : 101)	θ value	1.06291 (rank : 117)
Query Neighborhood Hits	213	Target Neighborhood Hits	2057	Shared Neighborhood Hits	94
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

NU214_HUMAN
NC score	0.050124 (rank : 102)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	213	Target Neighborhood Hits	657	Shared Neighborhood Hits	56
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

CG1_HUMAN
NC score	0.049861 (rank : 103)	θ value	0.365318 (rank : 91)
Query Neighborhood Hits	213	Target Neighborhood Hits	222	Shared Neighborhood Hits	32
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

MAD1_HUMAN
NC score	0.048879 (rank : 104)	θ value	5.27518 (rank : 182)
Query Neighborhood Hits	213	Target Neighborhood Hits	68	Shared Neighborhood Hits	26
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

RFIP1_HUMAN
NC score	0.048648 (rank : 105)	θ value	0.00175202 (rank : 51)
Query Neighborhood Hits	213	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q6WKZ4, Q6AZK4, Q6WKZ2, Q6WKZ6, Q86YV4, Q8TDL1, Q9H642	Gene names	RAB11FIP1, RCP
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein).

PPRB_HUMAN
NC score	0.044460 (rank : 106)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	213	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

R3HD2_MOUSE
NC score	0.044184 (rank : 107)	θ value	0.47712 (rank : 97)
Query Neighborhood Hits	213	Target Neighborhood Hits	397	Shared Neighborhood Hits	40
SwissProt Accessions	Q80TM6, Q80YB1, Q8BLS5, Q9CW50	Gene names	R3hdm2, Kiaa1002
Domain Architecture
Description	R3H domain-containing protein 2.

PO121_HUMAN
NC score	0.044000 (rank : 108)	θ value	0.47712 (rank : 96)
Query Neighborhood Hits	213	Target Neighborhood Hits	344	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

NUPL1_HUMAN
NC score	0.043132 (rank : 109)	θ value	0.0431538 (rank : 62)
Query Neighborhood Hits	213	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BVL2, O43160	Gene names	NUPL1, KIAA0410
Domain Architecture	No domain graphic available
Description	Nucleoporin p58/p45 (Nucleoporin-like 1).

MAGE1_HUMAN
NC score	0.042901 (rank : 110)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	213	Target Neighborhood Hits	1389	Shared Neighborhood Hits	100
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ATN1_HUMAN
NC score	0.042594 (rank : 111)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	213	Target Neighborhood Hits	676	Shared Neighborhood Hits	49
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

TARA_HUMAN
NC score	0.041822 (rank : 112)	θ value	4.03905 (rank : 165)
Query Neighborhood Hits	213	Target Neighborhood Hits	1626	Shared Neighborhood Hits	97
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PO121_MOUSE
NC score	0.040562 (rank : 113)	θ value	3.0926 (rank : 152)
Query Neighborhood Hits	213	Target Neighborhood Hits	345	Shared Neighborhood Hits	36
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

LR37A_HUMAN
NC score	0.040497 (rank : 114)	θ value	0.0961366 (rank : 69)
Query Neighborhood Hits	213	Target Neighborhood Hits	720	Shared Neighborhood Hits	48
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

UBP2L_MOUSE
NC score	0.039726 (rank : 115)	θ value	1.38821 (rank : 132)
Query Neighborhood Hits	213	Target Neighborhood Hits	173	Shared Neighborhood Hits	22
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

EP300_HUMAN
NC score	0.038704 (rank : 116)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	213	Target Neighborhood Hits	821	Shared Neighborhood Hits	56
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

UBP2L_HUMAN
NC score	0.037715 (rank : 117)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	213	Target Neighborhood Hits	170	Shared Neighborhood Hits	22
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

WBS14_MOUSE
NC score	0.037623 (rank : 118)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	213	Target Neighborhood Hits	171	Shared Neighborhood Hits	27
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

MUC5B_HUMAN
NC score	0.036785 (rank : 119)	θ value	0.0431538 (rank : 61)
Query Neighborhood Hits	213	Target Neighborhood Hits	1020	Shared Neighborhood Hits	58
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

GTSE1_MOUSE
NC score	0.036649 (rank : 120)	θ value	0.365318 (rank : 92)
Query Neighborhood Hits	213	Target Neighborhood Hits	245	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

SC24C_HUMAN
NC score	0.036551 (rank : 121)	θ value	1.06291 (rank : 123)
Query Neighborhood Hits	213	Target Neighborhood Hits	662	Shared Neighborhood Hits	52
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MAML1_MOUSE
NC score	0.034377 (rank : 122)	θ value	3.0926 (rank : 149)
Query Neighborhood Hits	213	Target Neighborhood Hits	279	Shared Neighborhood Hits	37
SwissProt Accessions	Q6T264, Q505D8, Q5SUC2, Q6PDK3, Q6ZQG5, Q8BIU5, Q8R3T0	Gene names	Maml1, Kiaa0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

ZIM10_HUMAN
NC score	0.033861 (rank : 123)	θ value	0.163984 (rank : 78)
Query Neighborhood Hits	213	Target Neighborhood Hits	577	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULJ6, Q7Z7E6	Gene names	RAI17, KIAA1224, ZIMP10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

EP400_HUMAN
NC score	0.033588 (rank : 124)	θ value	0.0961366 (rank : 67)
Query Neighborhood Hits	213	Target Neighborhood Hits	556	Shared Neighborhood Hits	38
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

GRIN1_MOUSE
NC score	0.032880 (rank : 125)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	213	Target Neighborhood Hits	337	Shared Neighborhood Hits	38
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

PCLO_MOUSE
NC score	0.032670 (rank : 126)	θ value	1.06291 (rank : 121)
Query Neighborhood Hits	213	Target Neighborhood Hits	2275	Shared Neighborhood Hits	93
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

HGS_HUMAN
NC score	0.032315 (rank : 127)	θ value	0.21417 (rank : 79)
Query Neighborhood Hits	213	Target Neighborhood Hits	517	Shared Neighborhood Hits	35
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

PF21B_MOUSE
NC score	0.030933 (rank : 128)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	213	Target Neighborhood Hits	278	Shared Neighborhood Hits	36
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

FIGN_HUMAN
NC score	0.030515 (rank : 129)	θ value	0.0113563 (rank : 52)
Query Neighborhood Hits	213	Target Neighborhood Hits	176	Shared Neighborhood Hits	14
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

PRG4_HUMAN
NC score	0.029201 (rank : 130)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	213	Target Neighborhood Hits	764	Shared Neighborhood Hits	42
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

EP400_MOUSE
NC score	0.029020 (rank : 131)	θ value	0.62314 (rank : 101)
Query Neighborhood Hits	213	Target Neighborhood Hits	592	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

NUP62_HUMAN
NC score	0.028758 (rank : 132)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	213	Target Neighborhood Hits	195	Shared Neighborhood Hits	14
SwissProt Accessions	P37198, Q503A4, Q96C43, Q9NSL1	Gene names	NUP62
Domain Architecture
Description	Nuclear pore glycoprotein p62 (62 kDa nucleoporin).

TCOF_MOUSE
NC score	0.028203 (rank : 133)	θ value	0.365318 (rank : 93)
Query Neighborhood Hits	213	Target Neighborhood Hits	471	Shared Neighborhood Hits	23
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

FIGN_MOUSE
NC score	0.027910 (rank : 134)	θ value	0.0961366 (rank : 68)
Query Neighborhood Hits	213	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

SC24B_HUMAN
NC score	0.027304 (rank : 135)	θ value	0.813845 (rank : 113)
Query Neighborhood Hits	213	Target Neighborhood Hits	108	Shared Neighborhood Hits	18
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

ZIM10_MOUSE
NC score	0.027282 (rank : 136)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	213	Target Neighborhood Hits	430	Shared Neighborhood Hits	28
SwissProt Accessions	Q6P1E1, Q6PDK9, Q6PF85, Q8BW47	Gene names	Rai17, Zimp10
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 17 (PIAS-like protein Zimp10).

BPTF_HUMAN
NC score	0.026748 (rank : 137)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	213	Target Neighborhood Hits	786	Shared Neighborhood Hits	37
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

NUPL_MOUSE
NC score	0.026519 (rank : 138)	θ value	3.0926 (rank : 151)
Query Neighborhood Hits	213	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

ZN326_HUMAN
NC score	0.025901 (rank : 139)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	213	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q5BKZ1, Q5VW93, Q5VW94, Q5VW96, Q5VW97, Q6NSA2, Q7Z638, Q7Z6C2	Gene names	ZNF326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326.

RAPH1_HUMAN
NC score	0.025865 (rank : 140)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	213	Target Neighborhood Hits	593	Shared Neighborhood Hits	38
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

SMG1_MOUSE
NC score	0.024383 (rank : 141)	θ value	0.813845 (rank : 114)
Query Neighborhood Hits	213	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SRBS1_MOUSE
NC score	0.024254 (rank : 142)	θ value	0.0961366 (rank : 72)
Query Neighborhood Hits	213	Target Neighborhood Hits	409	Shared Neighborhood Hits	21
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SDC3_MOUSE
NC score	0.024015 (rank : 143)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	213	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q64519, Q3UDD9, Q6ZQA4, Q7TQD4	Gene names	Sdc3, Kiaa0468
Domain Architecture
Description	Syndecan-3 precursor (SYND3).

SMG1_HUMAN
NC score	0.023999 (rank : 144)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	213	Target Neighborhood Hits	231	Shared Neighborhood Hits	8
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

UBR2_MOUSE
NC score	0.023680 (rank : 145)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	213	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

ENAH_MOUSE
NC score	0.023628 (rank : 146)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	213	Target Neighborhood Hits	919	Shared Neighborhood Hits	37
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

UBR2_HUMAN
NC score	0.023596 (rank : 147)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

PO6F2_MOUSE
NC score	0.023501 (rank : 148)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	213	Target Neighborhood Hits	639	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SRF_HUMAN
NC score	0.023427 (rank : 149)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	213	Target Neighborhood Hits	43	Shared Neighborhood Hits	6
SwissProt Accessions	P11831	Gene names	SRF
Domain Architecture
Description	Serum response factor (SRF).

RUSC2_HUMAN
NC score	0.023370 (rank : 150)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	213	Target Neighborhood Hits	205	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SRF_MOUSE
NC score	0.022812 (rank : 151)	θ value	3.0926 (rank : 156)
Query Neighborhood Hits	213	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JM73	Gene names	Srf
Domain Architecture	No domain graphic available
Description	Serum response factor (SRF).

BLNK_MOUSE
NC score	0.022576 (rank : 152)	θ value	0.62314 (rank : 100)
Query Neighborhood Hits	213	Target Neighborhood Hits	296	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QUN3, O88504	Gene names	Blnk, Bash, Ly57, Slp65
Domain Architecture	No domain graphic available
Description	B-cell linker protein (Cytoplasmic adapter protein) (B-cell adapter containing SH2 domain protein) (B-cell adapter containing Src homology 2 domain protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65) (Lymphocyte antigen 57).

SAPS1_MOUSE
NC score	0.022537 (rank : 153)	θ value	0.0961366 (rank : 71)
Query Neighborhood Hits	213	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

LMBL2_MOUSE
NC score	0.021998 (rank : 154)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	213	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P59178	Gene names	L3mbtl2
Domain Architecture
Description	Lethal(3)malignant brain tumor-like 2 protein (L(3)mbt-like 2 protein) (H-l(3)mbt-like protein).

MAP1B_MOUSE
NC score	0.021834 (rank : 155)	θ value	0.21417 (rank : 80)
Query Neighborhood Hits	213	Target Neighborhood Hits	977	Shared Neighborhood Hits	38
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MINT_HUMAN
NC score	0.021815 (rank : 156)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	213	Target Neighborhood Hits	1291	Shared Neighborhood Hits	56
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PO6F2_HUMAN
NC score	0.021757 (rank : 157)	θ value	1.38821 (rank : 130)
Query Neighborhood Hits	213	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

ZN326_MOUSE
NC score	0.021558 (rank : 158)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	213	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	O88291, Q8BSJ5, Q8K1X9, Q9CYG9	Gene names	Znf326, Zan75, Zfp326
Domain Architecture	No domain graphic available
Description	Zinc finger protein 326 (Zinc finger protein-associated with nuclear matrix of 75 kDa).

NUPL_HUMAN
NC score	0.020780 (rank : 159)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	213	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NKX61_HUMAN
NC score	0.020515 (rank : 160)	θ value	0.0252991 (rank : 58)
Query Neighborhood Hits	213	Target Neighborhood Hits	431	Shared Neighborhood Hits	19
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NRDC_MOUSE
NC score	0.020413 (rank : 161)	θ value	3.0926 (rank : 150)
Query Neighborhood Hits	213	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

AP180_HUMAN
NC score	0.020107 (rank : 162)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	213	Target Neighborhood Hits	183	Shared Neighborhood Hits	21
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

SFPQ_HUMAN
NC score	0.018866 (rank : 163)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	213	Target Neighborhood Hits	986	Shared Neighborhood Hits	44
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

MILK1_HUMAN
NC score	0.018478 (rank : 164)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	213	Target Neighborhood Hits	427	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N3F8, Q5TI16, Q7RTP5, Q8N3N8, Q9BVL9, Q9BY92, Q9UH43, Q9UH44, Q9UH45	Gene names	MIRAB13, KIAA1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NUMBL_HUMAN
NC score	0.018445 (rank : 165)	θ value	8.99809 (rank : 208)
Query Neighborhood Hits	213	Target Neighborhood Hits	394	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y6R0, Q7Z4J9	Gene names	NUMBL
Domain Architecture
Description	Numb-like protein (Numb-R).

TAF6_HUMAN
NC score	0.018135 (rank : 166)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	213	Target Neighborhood Hits	127	Shared Neighborhood Hits	14
SwissProt Accessions	P49848	Gene names	TAF6, TAF2E, TAFII70
Domain Architecture
Description	Transcription initiation factor TFIID subunit 6 (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII- 80) (TAFII80).

TAF3_HUMAN
NC score	0.017554 (rank : 167)	θ value	4.03905 (rank : 164)
Query Neighborhood Hits	213	Target Neighborhood Hits	568	Shared Neighborhood Hits	28
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

LR37B_HUMAN
NC score	0.017470 (rank : 168)	θ value	4.03905 (rank : 160)
Query Neighborhood Hits	213	Target Neighborhood Hits	392	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

NFRKB_HUMAN
NC score	0.017210 (rank : 169)	θ value	6.88961 (rank : 190)
Query Neighborhood Hits	213	Target Neighborhood Hits	211	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

ADRM1_HUMAN
NC score	0.016922 (rank : 170)	θ value	5.27518 (rank : 170)
Query Neighborhood Hits	213	Target Neighborhood Hits	81	Shared Neighborhood Hits	9
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

RANB3_MOUSE
NC score	0.016617 (rank : 171)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	213	Target Neighborhood Hits	123	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CT10, Q3TIS4, Q3U2G4, Q3UYG7	Gene names	Ranbp3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

FHOD1_MOUSE
NC score	0.016076 (rank : 172)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	213	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

HCN4_MOUSE
NC score	0.015945 (rank : 173)	θ value	5.27518 (rank : 181)
Query Neighborhood Hits	213	Target Neighborhood Hits	284	Shared Neighborhood Hits	23
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

LDB3_HUMAN
NC score	0.015930 (rank : 174)	θ value	0.279714 (rank : 88)
Query Neighborhood Hits	213	Target Neighborhood Hits	497	Shared Neighborhood Hits	27
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

HCN4_HUMAN
NC score	0.015802 (rank : 175)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	213	Target Neighborhood Hits	303	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

PHLB1_HUMAN
NC score	0.015772 (rank : 176)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	213	Target Neighborhood Hits	1038	Shared Neighborhood Hits	46
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

NKX61_MOUSE
NC score	0.015698 (rank : 177)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	213	Target Neighborhood Hits	439	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

SETB1_HUMAN
NC score	0.014487 (rank : 178)	θ value	3.0926 (rank : 154)
Query Neighborhood Hits	213	Target Neighborhood Hits	141	Shared Neighborhood Hits	7
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

RBM14_MOUSE
NC score	0.014403 (rank : 179)	θ value	1.06291 (rank : 122)
Query Neighborhood Hits	213	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C2Q3, Q3TJB6, Q91Z21, Q9DBI6	Gene names	Rbm14
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14).

FHOD1_HUMAN
NC score	0.014265 (rank : 180)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	213	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y613, Q59F76, Q6Y1F2, Q76MS8, Q8N521	Gene names	FHOD1, FHOS
Domain Architecture
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

RSNL2_HUMAN
NC score	0.013497 (rank : 181)	θ value	0.813845 (rank : 112)
Query Neighborhood Hits	213	Target Neighborhood Hits	136	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TFE2_HUMAN
NC score	0.012980 (rank : 182)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	213	Target Neighborhood Hits	161	Shared Neighborhood Hits	13
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

HXA3_MOUSE
NC score	0.012937 (rank : 183)	θ value	0.0252991 (rank : 56)
Query Neighborhood Hits	213	Target Neighborhood Hits	558	Shared Neighborhood Hits	23
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

SMAP1_HUMAN
NC score	0.012470 (rank : 184)	θ value	3.0926 (rank : 155)
Query Neighborhood Hits	213	Target Neighborhood Hits	98	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

TTC28_HUMAN
NC score	0.011686 (rank : 185)	θ value	4.03905 (rank : 167)
Query Neighborhood Hits	213	Target Neighborhood Hits	271	Shared Neighborhood Hits	17
SwissProt Accessions	Q96AY4, O95928, O95929, Q9NTE4, Q9UG31, Q9UGG5, Q9UPV8, Q9Y3S5	Gene names	TTC28, KIAA1043
Domain Architecture
Description	Tetratricopeptide repeat protein 28 (TPR repeat protein 28).

RBM14_HUMAN
NC score	0.011444 (rank : 186)	θ value	4.03905 (rank : 163)
Query Neighborhood Hits	213	Target Neighborhood Hits	213	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PK6, O75932, Q53GV1, Q68DQ9, Q96PK5	Gene names	RBM14, SIP
Domain Architecture	No domain graphic available
Description	RNA-binding protein 14 (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein).

COE3_HUMAN
NC score	0.011255 (rank : 187)	θ value	5.27518 (rank : 174)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_MOUSE
NC score	0.011109 (rank : 188)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	213	Target Neighborhood Hits	60	Shared Neighborhood Hits	7
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

WNK1_MOUSE
NC score	0.010582 (rank : 189)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	213	Target Neighborhood Hits	1179	Shared Neighborhood Hits	53
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

MCM3A_MOUSE
NC score	0.010396 (rank : 190)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	213	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUU9	Gene names	Mcm3ap, Ganp, Map80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

WNK1_HUMAN
NC score	0.010254 (rank : 191)	θ value	0.0193708 (rank : 55)
Query Neighborhood Hits	213	Target Neighborhood Hits	1158	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

B4GN3_MOUSE
NC score	0.010101 (rank : 192)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	213	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8S8	Gene names	B4galnt3
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 2 (EC 2.4.1.244) (NGalNAc-T2) (Beta- 1,4-N-acetylgalactosaminyltransferase III) (Beta4GalNAc-T3) (Beta4GalNAcT3).

XRN1_MOUSE
NC score	0.009829 (rank : 193)	θ value	4.03905 (rank : 168)
Query Neighborhood Hits	213	Target Neighborhood Hits	64	Shared Neighborhood Hits	4
SwissProt Accessions	P97789, O35651, P97790, Q3TE44, Q3TRE9, Q3UQL5	Gene names	Xrn1, Dhm2, Exo, Sep1
Domain Architecture	No domain graphic available
Description	5'-3' exoribonuclease 1 (EC 3.1.11.-) (mXRN1) (Strand-exchange protein 1 homolog) (Protein Dhm2).

ODBA_MOUSE
NC score	0.009462 (rank : 194)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	213	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P50136	Gene names	Bckdha
Domain Architecture
Description	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial precursor (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha).

CCAR1_HUMAN
NC score	0.009106 (rank : 195)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	213	Target Neighborhood Hits	444	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

MSH4_MOUSE
NC score	0.008611 (rank : 196)	θ value	4.03905 (rank : 162)
Query Neighborhood Hits	213	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q99MT2, Q920J1	Gene names	Msh4
Domain Architecture
Description	MutS protein homolog 4 (mMsh4).

DDEF2_MOUSE
NC score	0.008358 (rank : 197)	θ value	5.27518 (rank : 176)
Query Neighborhood Hits	213	Target Neighborhood Hits	625	Shared Neighborhood Hits	22
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DTX2_MOUSE
NC score	0.007490 (rank : 198)	θ value	5.27518 (rank : 177)
Query Neighborhood Hits	213	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3P2, Q9CZV3, Q9ER07, Q9ER08	Gene names	Dtx2
Domain Architecture
Description	Protein deltex-2 (Deltex-2) (Deltex2) (mDTX2).

IF4G1_HUMAN
NC score	0.007261 (rank : 199)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	213	Target Neighborhood Hits	347	Shared Neighborhood Hits	17
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ELF4_HUMAN
NC score	0.006453 (rank : 200)	θ value	5.27518 (rank : 178)
Query Neighborhood Hits	213	Target Neighborhood Hits	87	Shared Neighborhood Hits	8
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

EYA3_HUMAN
NC score	0.006401 (rank : 201)	θ value	5.27518 (rank : 179)
Query Neighborhood Hits	213	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

CJ006_HUMAN
NC score	0.006288 (rank : 202)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	213	Target Neighborhood Hits	122	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IX21, Q5W0L8, Q9NPE8	Gene names	C10orf6
Domain Architecture	No domain graphic available
Description	Protein C10orf6.

CEND3_HUMAN
NC score	0.006070 (rank : 203)	θ value	5.27518 (rank : 173)
Query Neighborhood Hits	213	Target Neighborhood Hits	275	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

NCA11_MOUSE
NC score	0.003979 (rank : 204)	θ value	5.27518 (rank : 184)
Query Neighborhood Hits	213	Target Neighborhood Hits	661	Shared Neighborhood Hits	27
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

FARP2_MOUSE
NC score	0.003282 (rank : 205)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	213	Target Neighborhood Hits	209	Shared Neighborhood Hits	9
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

LTBP2_HUMAN
NC score	0.003186 (rank : 206)	θ value	4.03905 (rank : 161)
Query Neighborhood Hits	213	Target Neighborhood Hits	552	Shared Neighborhood Hits	17
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SYNE1_HUMAN
NC score	0.003178 (rank : 207)	θ value	0.813845 (rank : 116)
Query Neighborhood Hits	213	Target Neighborhood Hits	1484	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CAC1E_HUMAN
NC score	0.002932 (rank : 208)	θ value	5.27518 (rank : 172)
Query Neighborhood Hits	213	Target Neighborhood Hits	148	Shared Neighborhood Hits	9
SwissProt Accessions	Q15878, Q14580, Q14581	Gene names	CACNA1E, CACH6, CACNL1A6
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

RXRA_MOUSE
NC score	0.002564 (rank : 209)	θ value	3.0926 (rank : 153)
Query Neighborhood Hits	213	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

K0999_HUMAN
NC score	0.002250 (rank : 210)	θ value	0.279714 (rank : 87)
Query Neighborhood Hits	213	Target Neighborhood Hits	899	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2K2, Q59FY2, Q5M9N1, Q6P3R6, Q8IYM8, Q9HA50	Gene names	KIAA0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

K0999_MOUSE
NC score	0.001956 (rank : 211)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	213	Target Neighborhood Hits	931	Shared Neighborhood Hits	22
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

GAK_MOUSE
NC score	0.001258 (rank : 212)	θ value	3.0926 (rank : 148)
Query Neighborhood Hits	213	Target Neighborhood Hits	964	Shared Neighborhood Hits	20
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

FGRL1_MOUSE
NC score	0.001227 (rank : 213)	θ value	5.27518 (rank : 180)
Query Neighborhood Hits	213	Target Neighborhood Hits	325	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

LTB1L_MOUSE
NC score	0.000742 (rank : 214)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	213	Target Neighborhood Hits	514	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

TNIK_HUMAN
NC score	0.000609 (rank : 215)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	213	Target Neighborhood Hits	1570	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

CTTB2_HUMAN
NC score	0.000463 (rank : 216)	θ value	5.27518 (rank : 175)
Query Neighborhood Hits	213	Target Neighborhood Hits	1061	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

TRIO_HUMAN
NC score	-0.000283 (rank : 217)	θ value	4.03905 (rank : 166)
Query Neighborhood Hits	213	Target Neighborhood Hits	1580	Shared Neighborhood Hits	26
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TIEG3_MOUSE
NC score	-0.000688 (rank : 218)	θ value	1.38821 (rank : 131)
Query Neighborhood Hits	213	Target Neighborhood Hits	774	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K1S5, Q8BI37	Gene names	Tieg3, Tieg2b
Domain Architecture
Description	Transforming growth factor-beta-inducible early growth response protein 3 (TGFB-inducible early growth response protein 3) (TIEG-3) (TGFB-inducible early growth response protein 2b).

MINK1_MOUSE
NC score	-0.000729 (rank : 219)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	213	Target Neighborhood Hits	1451	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

LAMC3_MOUSE
NC score	-0.000845 (rank : 220)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	213	Target Neighborhood Hits	624	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ACK1_HUMAN
NC score	-0.001149 (rank : 221)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	213	Target Neighborhood Hits	1140	Shared Neighborhood Hits	33
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ZBTB4_HUMAN
NC score	-0.001602 (rank : 222)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	213	Target Neighborhood Hits	926	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

PFTK1_MOUSE
NC score	-0.002663 (rank : 223)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	213	Target Neighborhood Hits	835	Shared Neighborhood Hits	11
SwissProt Accessions	O35495, O35848	Gene names	Pftk1
Domain Architecture
Description	Serine/threonine-protein kinase PFTAIRE-1 (EC 2.7.11.22).

SP4_HUMAN
NC score	-0.002921 (rank : 224)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	213	Target Neighborhood Hits	749	Shared Neighborhood Hits	17
SwissProt Accessions	Q02446, O60402	Gene names	SP4
Domain Architecture
Description	Transcription factor Sp4 (SPR-1).

ZN516_HUMAN
NC score	-0.003052 (rank : 225)	θ value	4.03905 (rank : 169)
Query Neighborhood Hits	213	Target Neighborhood Hits	854	Shared Neighborhood Hits	21
SwissProt Accessions	Q92618	Gene names	ZNF516, KIAA0222
Domain Architecture	No domain graphic available
Description	Zinc finger protein 516.

SP4_MOUSE
NC score	-0.003153 (rank : 226)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	213	Target Neighborhood Hits	759	Shared Neighborhood Hits	17
SwissProt Accessions	Q62445	Gene names	Sp4
Domain Architecture
Description	Transcription factor Sp4.

SP2_HUMAN
NC score	-0.003650 (rank : 227)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	213	Target Neighborhood Hits	747	Shared Neighborhood Hits	14
SwissProt Accessions	Q02086	Gene names	SP2, KIAA0048
Domain Architecture
Description	Transcription factor Sp2.