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Network neighborhood for query Sequence : MYCN_HUMAN

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MYCN_HUMAN
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MYCN_HUMAN
θ value	2.33393e-165 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	127	Target Neighborhood Hits	127	Shared Neighborhood Hits	127
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
θ value	4.72459e-150 (rank : 2)	NC score	0.981433 (rank : 2)
Query Neighborhood Hits	127	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	4.77967e-110 (rank : 3)	NC score	0.950047 (rank : 3)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_MOUSE
θ value	8.06329e-33 (rank : 4)	NC score	0.827060 (rank : 4)
Query Neighborhood Hits	127	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
θ value	1.37539e-32 (rank : 5)	NC score	0.820426 (rank : 5)
Query Neighborhood Hits	127	Target Neighborhood Hits	146	Shared Neighborhood Hits	54
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL1_HUMAN
θ value	1.24688e-25 (rank : 6)	NC score	0.778661 (rank : 6)
Query Neighborhood Hits	127	Target Neighborhood Hits	146	Shared Neighborhood Hits	58
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
θ value	7.56453e-23 (rank : 7)	NC score	0.743515 (rank : 7)
Query Neighborhood Hits	127	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCL1_MOUSE
θ value	1.33526e-19 (rank : 8)	NC score	0.742050 (rank : 8)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCB_MOUSE
θ value	2.43908e-13 (rank : 9)	NC score	0.689254 (rank : 9)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
θ value	2.79066e-09 (rank : 10)	NC score	0.621615 (rank : 10)
Query Neighborhood Hits	127	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
θ value	8.11959e-09 (rank : 11)	NC score	0.613570 (rank : 11)
Query Neighborhood Hits	127	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

FIGLA_MOUSE
θ value	6.43352e-06 (rank : 12)	NC score	0.338721 (rank : 16)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

NFH_MOUSE
θ value	2.44474e-05 (rank : 13)	NC score	0.038134 (rank : 138)
Query Neighborhood Hits	127	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MNT_HUMAN
θ value	7.1131e-05 (rank : 14)	NC score	0.304686 (rank : 20)
Query Neighborhood Hits	127	Target Neighborhood Hits	496	Shared Neighborhood Hits	51
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_MOUSE
θ value	7.1131e-05 (rank : 15)	NC score	0.312423 (rank : 19)
Query Neighborhood Hits	127	Target Neighborhood Hits	432	Shared Neighborhood Hits	48
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SRBP2_HUMAN
θ value	7.1131e-05 (rank : 16)	NC score	0.290005 (rank : 23)
Query Neighborhood Hits	127	Target Neighborhood Hits	133	Shared Neighborhood Hits	40
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

FIGLA_HUMAN
θ value	0.000602161 (rank : 17)	NC score	0.320982 (rank : 17)
Query Neighborhood Hits	127	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

MITF_HUMAN
θ value	0.000602161 (rank : 18)	NC score	0.288869 (rank : 25)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	42
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

USF2_HUMAN
θ value	0.000602161 (rank : 19)	NC score	0.361386 (rank : 12)
Query Neighborhood Hits	127	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	0.000602161 (rank : 20)	NC score	0.359233 (rank : 13)
Query Neighborhood Hits	127	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MITF_MOUSE
θ value	0.00102713 (rank : 21)	NC score	0.286236 (rank : 27)
Query Neighborhood Hits	127	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

USF1_HUMAN
θ value	0.00134147 (rank : 22)	NC score	0.356055 (rank : 15)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.00134147 (rank : 23)	NC score	0.358516 (rank : 14)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TFE3_HUMAN
θ value	0.00298849 (rank : 24)	NC score	0.293634 (rank : 22)
Query Neighborhood Hits	127	Target Neighborhood Hits	190	Shared Neighborhood Hits	47
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

WBS14_HUMAN
θ value	0.00298849 (rank : 25)	NC score	0.175194 (rank : 48)
Query Neighborhood Hits	127	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

GRIN1_HUMAN
θ value	0.00390308 (rank : 26)	NC score	0.058631 (rank : 119)
Query Neighborhood Hits	127	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ASCL1_HUMAN
θ value	0.00509761 (rank : 27)	NC score	0.250606 (rank : 32)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

MAD4_HUMAN
θ value	0.00509761 (rank : 28)	NC score	0.289872 (rank : 24)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

TFAP4_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.314233 (rank : 18)
Query Neighborhood Hits	127	Target Neighborhood Hits	289	Shared Neighborhood Hits	48
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

ASCL1_MOUSE
θ value	0.0113563 (rank : 30)	NC score	0.238249 (rank : 37)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

BHLH8_HUMAN
θ value	0.0113563 (rank : 31)	NC score	0.241005 (rank : 35)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_MOUSE
θ value	0.0113563 (rank : 32)	NC score	0.247501 (rank : 34)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

PTF1A_MOUSE
θ value	0.0193708 (rank : 33)	NC score	0.187526 (rank : 45)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

SRBP1_HUMAN
θ value	0.0252991 (rank : 34)	NC score	0.250968 (rank : 31)
Query Neighborhood Hits	127	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MAD4_MOUSE
θ value	0.0330416 (rank : 35)	NC score	0.238531 (rank : 36)
Query Neighborhood Hits	127	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MXI1_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.300630 (rank : 21)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

OGFR_HUMAN
θ value	0.0563607 (rank : 37)	NC score	0.038704 (rank : 137)
Query Neighborhood Hits	127	Target Neighborhood Hits	1582	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SRBP1_MOUSE
θ value	0.0736092 (rank : 38)	NC score	0.237097 (rank : 38)
Query Neighborhood Hits	127	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ARNT_HUMAN
θ value	0.0961366 (rank : 39)	NC score	0.140270 (rank : 54)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	33
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	0.0961366 (rank : 40)	NC score	0.135805 (rank : 59)
Query Neighborhood Hits	127	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ASCL3_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.173750 (rank : 49)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

MLX_HUMAN
θ value	0.125558 (rank : 42)	NC score	0.268579 (rank : 29)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	0.125558 (rank : 43)	NC score	0.270075 (rank : 28)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MXI1_HUMAN
θ value	0.125558 (rank : 44)	NC score	0.288526 (rank : 26)
Query Neighborhood Hits	127	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

NDF2_HUMAN
θ value	0.125558 (rank : 45)	NC score	0.120114 (rank : 66)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	0.125558 (rank : 46)	NC score	0.119961 (rank : 67)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	36
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

PTF1A_HUMAN
θ value	0.163984 (rank : 47)	NC score	0.184899 (rank : 47)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

ARNT2_HUMAN
θ value	0.21417 (rank : 48)	NC score	0.127967 (rank : 63)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0.21417 (rank : 49)	NC score	0.128427 (rank : 61)
Query Neighborhood Hits	127	Target Neighborhood Hits	115	Shared Neighborhood Hits	33
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ATS13_HUMAN
θ value	0.21417 (rank : 50)	NC score	0.014809 (rank : 161)
Query Neighborhood Hits	127	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

DEND_MOUSE
θ value	0.21417 (rank : 51)	NC score	0.046402 (rank : 134)
Query Neighborhood Hits	127	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

ASCL3_MOUSE
θ value	0.279714 (rank : 52)	NC score	0.160347 (rank : 52)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

ID1_HUMAN
θ value	0.279714 (rank : 53)	NC score	0.130465 (rank : 60)
Query Neighborhood Hits	127	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ID1_MOUSE
θ value	0.279714 (rank : 54)	NC score	0.128009 (rank : 62)
Query Neighborhood Hits	127	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ITF2_HUMAN
θ value	0.279714 (rank : 55)	NC score	0.085149 (rank : 89)
Query Neighborhood Hits	127	Target Neighborhood Hits	168	Shared Neighborhood Hits	24
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

ITF2_MOUSE
θ value	0.279714 (rank : 56)	NC score	0.086380 (rank : 88)
Query Neighborhood Hits	127	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

PTN13_MOUSE
θ value	0.279714 (rank : 57)	NC score	0.010609 (rank : 173)
Query Neighborhood Hits	127	Target Neighborhood Hits	426	Shared Neighborhood Hits	5
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

ASCL2_MOUSE
θ value	0.365318 (rank : 58)	NC score	0.219993 (rank : 41)
Query Neighborhood Hits	127	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

GDIA_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.063529 (rank : 113)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P31150, P50394, Q7Z2G6, Q7Z2G9, Q7Z2H5, Q7Z2I6	Gene names	GDI1, OPHN2, RABGDIA, XAP4
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (XAP-4) (Oligophrenin- 2).

HAND2_HUMAN
θ value	0.47712 (rank : 60)	NC score	0.194363 (rank : 43)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
θ value	0.47712 (rank : 61)	NC score	0.194363 (rank : 44)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

HTF4_HUMAN
θ value	0.47712 (rank : 62)	NC score	0.078793 (rank : 97)
Query Neighborhood Hits	127	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

HAND1_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.166016 (rank : 51)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

HAND1_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.171338 (rank : 50)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	39
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HTF4_MOUSE
θ value	0.62314 (rank : 65)	NC score	0.077577 (rank : 99)
Query Neighborhood Hits	127	Target Neighborhood Hits	153	Shared Neighborhood Hits	21
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

NOL6_MOUSE
θ value	0.62314 (rank : 66)	NC score	0.032562 (rank : 140)
Query Neighborhood Hits	127	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

EPN3_MOUSE
θ value	0.813845 (rank : 67)	NC score	0.027184 (rank : 145)
Query Neighborhood Hits	127	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

GDIA_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.060480 (rank : 117)
Query Neighborhood Hits	127	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P50396, Q8VHM3, Q91Y71, Q96CX5	Gene names	Gdi1, Rabgdia
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1).

GDIB_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.060205 (rank : 118)
Query Neighborhood Hits	127	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q61598, Q541Z9, Q8C530, Q9D8M9	Gene names	Gdi2, Gdi3
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) (GDI-3).

MAD1_MOUSE
θ value	0.813845 (rank : 70)	NC score	0.208077 (rank : 42)
Query Neighborhood Hits	127	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

TFEB_HUMAN
θ value	0.813845 (rank : 71)	NC score	0.231732 (rank : 40)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	40
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.813845 (rank : 72)	NC score	0.232756 (rank : 39)
Query Neighborhood Hits	127	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

ZFP28_HUMAN
θ value	0.813845 (rank : 73)	NC score	-0.000950 (rank : 186)
Query Neighborhood Hits	127	Target Neighborhood Hits	843	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

CS007_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.031409 (rank : 141)
Query Neighborhood Hits	127	Target Neighborhood Hits	464	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

NGN3_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.115057 (rank : 68)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

ACINU_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.042919 (rank : 135)
Query Neighborhood Hits	127	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

ASCL2_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.185394 (rank : 46)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

FGFP3_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.039515 (rank : 136)
Query Neighborhood Hits	127	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

MAD3_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.248938 (rank : 33)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	31
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MYH6_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.013277 (rank : 165)
Query Neighborhood Hits	127	Target Neighborhood Hits	1426	Shared Neighborhood Hits	19
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PHLPP_HUMAN
θ value	1.81305 (rank : 81)	NC score	0.014047 (rank : 163)
Query Neighborhood Hits	127	Target Neighborhood Hits	604	Shared Neighborhood Hits	14
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

CASP_MOUSE
θ value	2.36792 (rank : 82)	NC score	0.020284 (rank : 152)
Query Neighborhood Hits	127	Target Neighborhood Hits	1152	Shared Neighborhood Hits	15
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.022399 (rank : 150)
Query Neighborhood Hits	127	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GDIB_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.051675 (rank : 129)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P50395, O43928, Q9UQM6	Gene names	GDI2, RABGDIB
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2).

MYH7_HUMAN
θ value	2.36792 (rank : 85)	NC score	0.013213 (rank : 166)
Query Neighborhood Hits	127	Target Neighborhood Hits	1559	Shared Neighborhood Hits	20
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PEPL_MOUSE
θ value	2.36792 (rank : 86)	NC score	0.012843 (rank : 167)
Query Neighborhood Hits	127	Target Neighborhood Hits	1105	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SMC4_HUMAN
θ value	2.36792 (rank : 87)	NC score	0.014867 (rank : 160)
Query Neighborhood Hits	127	Target Neighborhood Hits	937	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

CASP_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.019595 (rank : 153)
Query Neighborhood Hits	127	Target Neighborhood Hits	1131	Shared Neighborhood Hits	18
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CDS1_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.015286 (rank : 158)
Query Neighborhood Hits	127	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CUTL1_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.023569 (rank : 149)
Query Neighborhood Hits	127	Target Neighborhood Hits	1574	Shared Neighborhood Hits	29
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FOG1_MOUSE
θ value	3.0926 (rank : 91)	NC score	0.008176 (rank : 176)
Query Neighborhood Hits	127	Target Neighborhood Hits	1237	Shared Neighborhood Hits	23
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

MAD3_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.256197 (rank : 30)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

P80C_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.032952 (rank : 139)
Query Neighborhood Hits	127	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

SPIB_MOUSE
θ value	3.0926 (rank : 94)	NC score	0.027163 (rank : 146)
Query Neighborhood Hits	127	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

CAMKV_HUMAN
θ value	4.03905 (rank : 95)	NC score	-0.000340 (rank : 185)
Query Neighborhood Hits	127	Target Neighborhood Hits	1084	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

K0310_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.029809 (rank : 143)
Query Neighborhood Hits	127	Target Neighborhood Hits	420	Shared Neighborhood Hits	17
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MYH6_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.012532 (rank : 168)
Query Neighborhood Hits	127	Target Neighborhood Hits	1501	Shared Neighborhood Hits	22
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

ZN142_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.000066 (rank : 184)
Query Neighborhood Hits	127	Target Neighborhood Hits	1007	Shared Neighborhood Hits	14
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

HXB3_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.001649 (rank : 182)
Query Neighborhood Hits	127	Target Neighborhood Hits	493	Shared Neighborhood Hits	6
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

RHG05_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.015626 (rank : 157)
Query Neighborhood Hits	127	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.015180 (rank : 159)
Query Neighborhood Hits	127	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SALL1_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.001315 (rank : 183)
Query Neighborhood Hits	127	Target Neighborhood Hits	826	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

SALL4_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.001791 (rank : 181)
Query Neighborhood Hits	127	Target Neighborhood Hits	799	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJQ4	Gene names	SALL4
Domain Architecture
Description	Sal-like protein 4 (Zinc finger protein SALL4).

SDPR_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.025945 (rank : 148)
Query Neighborhood Hits	127	Target Neighborhood Hits	485	Shared Neighborhood Hits	13
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TB182_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.030419 (rank : 142)
Query Neighborhood Hits	127	Target Neighborhood Hits	414	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TRIPB_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.013853 (rank : 164)
Query Neighborhood Hits	127	Target Neighborhood Hits	1587	Shared Neighborhood Hits	28
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

TTBK2_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.003709 (rank : 179)
Query Neighborhood Hits	127	Target Neighborhood Hits	811	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

WASF2_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.014698 (rank : 162)
Query Neighborhood Hits	127	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

CEL_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.009512 (rank : 174)
Query Neighborhood Hits	127	Target Neighborhood Hits	896	Shared Neighborhood Hits	21
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CO002_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.012487 (rank : 169)
Query Neighborhood Hits	127	Target Neighborhood Hits	387	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

CSKI1_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.008247 (rank : 175)
Query Neighborhood Hits	127	Target Neighborhood Hits	1031	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EPN1_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.028102 (rank : 144)
Query Neighborhood Hits	127	Target Neighborhood Hits	206	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

IL16_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.011426 (rank : 172)
Query Neighborhood Hits	127	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

IRS2_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.018518 (rank : 154)
Query Neighborhood Hits	127	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

OSBP2_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.015762 (rank : 156)
Query Neighborhood Hits	127	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

POT15_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.003741 (rank : 178)
Query Neighborhood Hits	127	Target Neighborhood Hits	893	Shared Neighborhood Hits	16
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

SRRM2_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.021151 (rank : 151)
Query Neighborhood Hits	127	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ETV3_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.011677 (rank : 171)
Query Neighborhood Hits	127	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

ID4_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.073985 (rank : 102)
Query Neighborhood Hits	127	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

ID4_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.072338 (rank : 106)
Query Neighborhood Hits	127	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	P41139	Gene names	Id4, Id-4, Idb4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

IWS1_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.026337 (rank : 147)
Query Neighborhood Hits	127	Target Neighborhood Hits	1258	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MAGD4_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.006184 (rank : 177)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

NPM2_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.012090 (rank : 170)
Query Neighborhood Hits	127	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q80W85, Q8BW23	Gene names	Npm2
Domain Architecture
Description	Nucleoplasmin-2.

PCLO_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.016560 (rank : 155)
Query Neighborhood Hits	127	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TTBK2_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.003334 (rank : 180)
Query Neighborhood Hits	127	Target Neighborhood Hits	822	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

WBS14_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.124875 (rank : 65)
Query Neighborhood Hits	127	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

ZN275_HUMAN
θ value	8.99809 (rank : 127)	NC score	-0.002311 (rank : 187)
Query Neighborhood Hits	127	Target Neighborhood Hits	761	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NSD4	Gene names	ZNF275
Domain Architecture	No domain graphic available
Description	Zinc finger protein 275.

ATOH1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.109769 (rank : 70)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

ATOH1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.110254 (rank : 69)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

BHLH3_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.051119 (rank : 131)
Query Neighborhood Hits	127	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH4_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.054284 (rank : 125)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.054077 (rank : 126)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BMAL1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.079257 (rank : 93)
Query Neighborhood Hits	127	Target Neighborhood Hits	115	Shared Neighborhood Hits	33
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.078797 (rank : 96)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

HEN1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.092814 (rank : 77)
Query Neighborhood Hits	127	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.094808 (rank : 73)
Query Neighborhood Hits	127	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.092616 (rank : 78)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.091896 (rank : 79)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEY1_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.050366 (rank : 132)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.051601 (rank : 130)
Query Neighborhood Hits	127	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.055388 (rank : 123)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.055631 (rank : 122)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

ID2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.063326 (rank : 114)
Query Neighborhood Hits	127	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	Q02363	Gene names	ID2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

ID2_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.058505 (rank : 120)
Query Neighborhood Hits	127	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P41136, O88604	Gene names	Id2, Id-2, Idb2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

LYL1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.093806 (rank : 75)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.094170 (rank : 74)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

MAD1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.143353 (rank : 53)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MUSC_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.072930 (rank : 104)
Query Neighborhood Hits	127	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

MUSC_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.073664 (rank : 103)
Query Neighborhood Hits	127	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MYF5_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.078929 (rank : 94)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF5_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.080936 (rank : 92)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

MYF6_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.090744 (rank : 83)
Query Neighborhood Hits	127	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

MYF6_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.086669 (rank : 87)
Query Neighborhood Hits	127	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

MYOD1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.076824 (rank : 101)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

MYOD1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.078046 (rank : 98)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

MYOG_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.087388 (rank : 85)
Query Neighborhood Hits	127	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.087196 (rank : 86)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

NDF1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.077163 (rank : 100)
Query Neighborhood Hits	127	Target Neighborhood Hits	186	Shared Neighborhood Hits	34
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.078871 (rank : 95)
Query Neighborhood Hits	127	Target Neighborhood Hits	209	Shared Neighborhood Hits	35
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF4_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.062880 (rank : 115)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

NDF4_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.063733 (rank : 112)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

NDF6_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.065808 (rank : 110)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.065618 (rank : 111)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

NGN1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.071207 (rank : 107)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

NGN1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.072773 (rank : 105)
Query Neighborhood Hits	127	Target Neighborhood Hits	87	Shared Neighborhood Hits	26
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

NGN2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.091715 (rank : 80)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.091248 (rank : 82)
Query Neighborhood Hits	127	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

NGN3_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.091705 (rank : 81)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

OLIG1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.050117 (rank : 133)
Query Neighborhood Hits	127	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

OLIG2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.051870 (rank : 128)
Query Neighborhood Hits	127	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

OLIG2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.052336 (rank : 127)
Query Neighborhood Hits	127	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

SCX_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.124919 (rank : 64)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

TAL1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.102063 (rank : 72)
Query Neighborhood Hits	127	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

TAL1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.105168 (rank : 71)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.084565 (rank : 90)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.084288 (rank : 91)
Query Neighborhood Hits	127	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

TCF15_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.089765 (rank : 84)
Query Neighborhood Hits	127	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

TCF15_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.093438 (rank : 76)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

TCF21_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.069471 (rank : 108)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.068632 (rank : 109)
Query Neighborhood Hits	127	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCFL5_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.062617 (rank : 116)
Query Neighborhood Hits	127	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.056963 (rank : 121)
Query Neighborhood Hits	127	Target Neighborhood Hits	161	Shared Neighborhood Hits	21
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

TFE2_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.054679 (rank : 124)
Query Neighborhood Hits	127	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

TWST1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.136354 (rank : 57)
Query Neighborhood Hits	127	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.136185 (rank : 58)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

TWST2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.137238 (rank : 55)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.137212 (rank : 56)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

Hits sorted by NC score

MYCN_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.33393e-165 (rank : 1)
Query Neighborhood Hits	127	Target Neighborhood Hits	127	Shared Neighborhood Hits	127
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
NC score	0.981433 (rank : 2)	θ value	4.72459e-150 (rank : 2)
Query Neighborhood Hits	127	Target Neighborhood Hits	125	Shared Neighborhood Hits	86
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
NC score	0.950047 (rank : 3)	θ value	4.77967e-110 (rank : 3)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_MOUSE
NC score	0.827060 (rank : 4)	θ value	8.06329e-33 (rank : 4)
Query Neighborhood Hits	127	Target Neighborhood Hits	125	Shared Neighborhood Hits	56
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_HUMAN
NC score	0.820426 (rank : 5)	θ value	1.37539e-32 (rank : 5)
Query Neighborhood Hits	127	Target Neighborhood Hits	146	Shared Neighborhood Hits	54
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYCL1_HUMAN
NC score	0.778661 (rank : 6)	θ value	1.24688e-25 (rank : 6)
Query Neighborhood Hits	127	Target Neighborhood Hits	146	Shared Neighborhood Hits	58
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL2_HUMAN
NC score	0.743515 (rank : 7)	θ value	7.56453e-23 (rank : 7)
Query Neighborhood Hits	127	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	P12525	Gene names	MYCL2
Domain Architecture
Description	L-myc-2 protein.

MYCL1_MOUSE
NC score	0.742050 (rank : 8)	θ value	1.33526e-19 (rank : 8)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	56
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCB_MOUSE
NC score	0.689254 (rank : 9)	θ value	2.43908e-13 (rank : 9)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P8Z1, Q9D6E3	Gene names	Mycb, Bmyc
Domain Architecture	No domain graphic available
Description	Protein B-Myc.

MAX_HUMAN
NC score	0.621615 (rank : 10)	θ value	2.79066e-09 (rank : 10)
Query Neighborhood Hits	127	Target Neighborhood Hits	125	Shared Neighborhood Hits	52
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MAX_MOUSE
NC score	0.613570 (rank : 11)	θ value	8.11959e-09 (rank : 11)
Query Neighborhood Hits	127	Target Neighborhood Hits	139	Shared Neighborhood Hits	54
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

USF2_HUMAN
NC score	0.361386 (rank : 12)	θ value	0.000602161 (rank : 19)
Query Neighborhood Hits	127	Target Neighborhood Hits	155	Shared Neighborhood Hits	48
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
NC score	0.359233 (rank : 13)	θ value	0.000602161 (rank : 20)
Query Neighborhood Hits	127	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

USF1_MOUSE
NC score	0.358516 (rank : 14)	θ value	0.00134147 (rank : 23)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	41
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.356055 (rank : 15)	θ value	0.00134147 (rank : 22)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	41
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

FIGLA_MOUSE
NC score	0.338721 (rank : 16)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	O55208	Gene names	Figla
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

FIGLA_HUMAN
NC score	0.320982 (rank : 17)	θ value	0.000602161 (rank : 17)
Query Neighborhood Hits	127	Target Neighborhood Hits	108	Shared Neighborhood Hits	43
SwissProt Accessions	Q6QHK4	Gene names	FIGLA
Domain Architecture	No domain graphic available
Description	Factor in the germline alpha (Transcription factor FIGa) (FIGalpha).

TFAP4_HUMAN
NC score	0.314233 (rank : 18)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	127	Target Neighborhood Hits	289	Shared Neighborhood Hits	48
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

MNT_MOUSE
NC score	0.312423 (rank : 19)	θ value	7.1131e-05 (rank : 15)
Query Neighborhood Hits	127	Target Neighborhood Hits	432	Shared Neighborhood Hits	48
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MNT_HUMAN
NC score	0.304686 (rank : 20)	θ value	7.1131e-05 (rank : 14)
Query Neighborhood Hits	127	Target Neighborhood Hits	496	Shared Neighborhood Hits	51
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MXI1_MOUSE
NC score	0.300630 (rank : 21)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	36
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

TFE3_HUMAN
NC score	0.293634 (rank : 22)	θ value	0.00298849 (rank : 24)
Query Neighborhood Hits	127	Target Neighborhood Hits	190	Shared Neighborhood Hits	47
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

SRBP2_HUMAN
NC score	0.290005 (rank : 23)	θ value	7.1131e-05 (rank : 16)
Query Neighborhood Hits	127	Target Neighborhood Hits	133	Shared Neighborhood Hits	40
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

MAD4_HUMAN
NC score	0.289872 (rank : 24)	θ value	0.00509761 (rank : 28)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MITF_HUMAN
NC score	0.288869 (rank : 25)	θ value	0.000602161 (rank : 18)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	42
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MXI1_HUMAN
NC score	0.288526 (rank : 26)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	127	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MITF_MOUSE
NC score	0.286236 (rank : 27)	θ value	0.00102713 (rank : 21)
Query Neighborhood Hits	127	Target Neighborhood Hits	115	Shared Neighborhood Hits	42
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_MOUSE
NC score	0.270075 (rank : 28)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.268579 (rank : 29)	θ value	0.125558 (rank : 42)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MAD3_HUMAN
NC score	0.256197 (rank : 30)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

SRBP1_HUMAN
NC score	0.250968 (rank : 31)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	127	Target Neighborhood Hits	225	Shared Neighborhood Hits	40
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

ASCL1_HUMAN
NC score	0.250606 (rank : 32)	θ value	0.00509761 (rank : 27)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	34
SwissProt Accessions	P50553, Q9BQ30	Gene names	ASCL1, ASH1
Domain Architecture
Description	Achaete-scute homolog 1 (HASH1).

MAD3_MOUSE
NC score	0.248938 (rank : 33)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	127	Target Neighborhood Hits	94	Shared Neighborhood Hits	31
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

BHLH8_MOUSE
NC score	0.247501 (rank : 34)	θ value	0.0113563 (rank : 32)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYC3, Q9QYE4	Gene names	Bhlhb8, Mist1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

BHLH8_HUMAN
NC score	0.241005 (rank : 35)	θ value	0.0113563 (rank : 31)
Query Neighborhood Hits	127	Target Neighborhood Hits	123	Shared Neighborhood Hits	46
SwissProt Accessions	Q7RTS1	Gene names	BHLHB8, MIST1
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 8 (bHLHB8) (Muscle, intestine and stomach expression 1) (MIST-1).

MAD4_MOUSE
NC score	0.238531 (rank : 36)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	127	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

ASCL1_MOUSE
NC score	0.238249 (rank : 37)	θ value	0.0113563 (rank : 30)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	Q02067	Gene names	Ascl1, Ash1, Mash-1, Mash1
Domain Architecture
Description	Achaete-scute homolog 1 (Mash-1).

SRBP1_MOUSE
NC score	0.237097 (rank : 38)	θ value	0.0736092 (rank : 38)
Query Neighborhood Hits	127	Target Neighborhood Hits	384	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TFEB_MOUSE
NC score	0.232756 (rank : 39)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	127	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.231732 (rank : 40)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	40
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

ASCL2_MOUSE
NC score	0.219993 (rank : 41)	θ value	0.365318 (rank : 58)
Query Neighborhood Hits	127	Target Neighborhood Hits	98	Shared Neighborhood Hits	36
SwissProt Accessions	O35885, Q9WUJ7	Gene names	Ascl2, Mash2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash-2).

MAD1_MOUSE
NC score	0.208077 (rank : 42)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	127	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

HAND2_HUMAN
NC score	0.194363 (rank : 43)	θ value	0.47712 (rank : 60)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	P61296, O95300, O95301, P97833	Gene names	HAND2, DHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND).

HAND2_MOUSE
NC score	0.194363 (rank : 44)	θ value	0.47712 (rank : 61)
Query Neighborhood Hits	127	Target Neighborhood Hits	99	Shared Neighborhood Hits	43
SwissProt Accessions	Q61039, Q61100	Gene names	Hand2, Dhand, Hed, Thing2
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 2 (Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) (dHAND) (Helix-loop-helix transcription factor expressed in embryo and deciduum) (Thing-2).

PTF1A_MOUSE
NC score	0.187526 (rank : 45)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QX98, Q9QYF5, Q9QYF6	Gene names	Ptf1a, Ptf1p48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

ASCL2_HUMAN
NC score	0.185394 (rank : 46)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	33
SwissProt Accessions	Q99929, Q9UM68	Gene names	ASCL2
Domain Architecture
Description	Achaete-scute homolog 2 (Mash2) (HASH2).

PTF1A_HUMAN
NC score	0.184899 (rank : 47)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	39
SwissProt Accessions	Q7RTS3, Q9HC25	Gene names	PTF1A, PTF1P48
Domain Architecture	No domain graphic available
Description	Pancreas transcription factor 1 subunit alpha (Pancreas-specific transcription factor 1a) (bHLH transcription factor p48) (p48 DNA- binding subunit of transcription factor PTF1) (PTF1-p48).

WBS14_HUMAN
NC score	0.175194 (rank : 48)	θ value	0.00298849 (rank : 25)
Query Neighborhood Hits	127	Target Neighborhood Hits	273	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

ASCL3_HUMAN
NC score	0.173750 (rank : 49)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NQ33, Q8WYQ6	Gene names	ASCL3, HASH3, SGN1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1).

HAND1_MOUSE
NC score	0.171338 (rank : 50)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	39
SwissProt Accessions	Q64279, Q61099	Gene names	Hand1, Ehand, Hxt, Thing1
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND) (Helix-loop-helix transcription factor expressed in extraembryonic mesoderm and trophoblast) (Thing-1) (Th1).

HAND1_HUMAN
NC score	0.166016 (rank : 51)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	O96004	Gene names	HAND1, EHAND
Domain Architecture
Description	Heart- and neural crest derivatives-expressed protein 1 (Extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1) (eHAND).

ASCL3_MOUSE
NC score	0.160347 (rank : 52)	θ value	0.279714 (rank : 52)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JJR7	Gene names	Ascl3, Mash3, Sgn1
Domain Architecture
Description	Achaete-scute homolog 3 (bHLH transcriptional regulator Sgn-1) (Mash- 3).

MAD1_HUMAN
NC score	0.143353 (rank : 53)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	27
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

ARNT_HUMAN
NC score	0.140270 (rank : 54)	θ value	0.0961366 (rank : 39)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	33
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

TWST2_HUMAN
NC score	0.137238 (rank : 55)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WVJ9	Gene names	TWIST2, DERMO1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST2_MOUSE
NC score	0.137212 (rank : 56)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	127	Target Neighborhood Hits	107	Shared Neighborhood Hits	38
SwissProt Accessions	Q9D030	Gene names	Twist2, Dermo1
Domain Architecture
Description	Twist-related protein 2 (Dermis expressed protein 1) (Dermo-1).

TWST1_HUMAN
NC score	0.136354 (rank : 57)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	127	Target Neighborhood Hits	93	Shared Neighborhood Hits	37
SwissProt Accessions	Q15672, Q92487, Q99804	Gene names	TWIST1, TWIST
Domain Architecture
Description	Twist-related protein 1 (H-twist).

TWST1_MOUSE
NC score	0.136185 (rank : 58)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	127	Target Neighborhood Hits	101	Shared Neighborhood Hits	37
SwissProt Accessions	P26687	Gene names	Twist1, Twist
Domain Architecture
Description	Twist-related protein 1 (M-twist).

ARNT_MOUSE
NC score	0.135805 (rank : 59)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	127	Target Neighborhood Hits	213	Shared Neighborhood Hits	34
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ID1_HUMAN
NC score	0.130465 (rank : 60)	θ value	0.279714 (rank : 53)
Query Neighborhood Hits	127	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	P41134, O00651, O00652, Q16371, Q16377, Q5TE66, Q5TE67, Q969Z7, Q9H0Z5, Q9H109	Gene names	ID1, ID
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ARNT2_MOUSE
NC score	0.128427 (rank : 61)	θ value	0.21417 (rank : 49)
Query Neighborhood Hits	127	Target Neighborhood Hits	115	Shared Neighborhood Hits	33
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ID1_MOUSE
NC score	0.128009 (rank : 62)	θ value	0.279714 (rank : 54)
Query Neighborhood Hits	127	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	P20067, Q61101, Q9D897	Gene names	Id1, Id, Id-1, Idb1
Domain Architecture
Description	DNA-binding protein inhibitor ID-1 (Inhibitor of DNA binding 1).

ARNT2_HUMAN
NC score	0.127967 (rank : 63)	θ value	0.21417 (rank : 48)
Query Neighborhood Hits	127	Target Neighborhood Hits	109	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

SCX_MOUSE
NC score	0.124919 (rank : 64)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	Q64124	Gene names	Scx
Domain Architecture
Description	Basic helix-loop-helix transcription factor scleraxis.

WBS14_MOUSE
NC score	0.124875 (rank : 65)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	127	Target Neighborhood Hits	171	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

NDF2_HUMAN
NC score	0.120114 (rank : 66)	θ value	0.125558 (rank : 45)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	36
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
NC score	0.119961 (rank : 67)	θ value	0.125558 (rank : 46)
Query Neighborhood Hits	127	Target Neighborhood Hits	111	Shared Neighborhood Hits	36
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NGN3_HUMAN
NC score	0.115057 (rank : 68)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y4Z2, Q9BY24	Gene names	NEUROG3, NGN3
Domain Architecture
Description	Neurogenin 3.

ATOH1_MOUSE
NC score	0.110254 (rank : 69)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	36
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

ATOH1_HUMAN
NC score	0.109769 (rank : 70)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	127	Target Neighborhood Hits	97	Shared Neighborhood Hits	35
SwissProt Accessions	Q92858	Gene names	ATOH1, ATH1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein hATH-1).

TAL1_MOUSE
NC score	0.105168 (rank : 71)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	127	Target Neighborhood Hits	110	Shared Neighborhood Hits	43
SwissProt Accessions	P22091	Gene names	Tal1, Scl, Tal-1
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein homolog (TAL-1 protein) (Stem cell protein).

TAL1_HUMAN
NC score	0.102063 (rank : 72)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	127	Target Neighborhood Hits	112	Shared Neighborhood Hits	41
SwissProt Accessions	P17542	Gene names	TAL1, SCL, TCL5
Domain Architecture
Description	T-cell acute lymphocytic leukemia-1 protein (TAL-1 protein) (Stem cell protein) (T-cell leukemia/lymphoma-5 protein).

HEN1_MOUSE
NC score	0.094808 (rank : 73)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	127	Target Neighborhood Hits	86	Shared Neighborhood Hits	33
SwissProt Accessions	Q02576	Gene names	Nhlh1, Hen1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

LYL1_MOUSE
NC score	0.094170 (rank : 74)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	127	Target Neighborhood Hits	102	Shared Neighborhood Hits	31
SwissProt Accessions	P27792	Gene names	Lyl1, Lyl-1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

LYL1_HUMAN
NC score	0.093806 (rank : 75)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	127	Target Neighborhood Hits	113	Shared Neighborhood Hits	34
SwissProt Accessions	P12980, O76102	Gene names	LYL1
Domain Architecture
Description	Protein lyl-1 (Lymphoblastic leukemia-derived sequence 1).

TCF15_MOUSE
NC score	0.093438 (rank : 76)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	27
SwissProt Accessions	Q60756, Q60788	Gene names	Tcf15, Bhlhec2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis) (Meso1).

HEN1_HUMAN
NC score	0.092814 (rank : 77)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	127	Target Neighborhood Hits	88	Shared Neighborhood Hits	33
SwissProt Accessions	Q02575	Gene names	NHLH1, HEN1
Domain Architecture
Description	Helix-loop-helix protein 1 (HEN1) (Nescient helix loop helix 1) (NSCL- 1).

HEN2_HUMAN
NC score	0.092616 (rank : 78)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q02577	Gene names	NHLH2, HEN2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

HEN2_MOUSE
NC score	0.091896 (rank : 79)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	33
SwissProt Accessions	Q64221	Gene names	Nhlh2, Hen2
Domain Architecture
Description	Helix-loop-helix protein 2 (HEN2) (Nescient helix loop helix 2) (NSCL- 2).

NGN2_HUMAN
NC score	0.091715 (rank : 80)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	127	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H2A3, Q8N416	Gene names	NEUROG2, NGN2
Domain Architecture	No domain graphic available
Description	Neurogenin 2.

NGN3_MOUSE
NC score	0.091705 (rank : 81)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	127	Target Neighborhood Hits	90	Shared Neighborhood Hits	31
SwissProt Accessions	P70661	Gene names	Neurog3, Ath4b, Atoh5, Ngn3
Domain Architecture
Description	Neurogenin 3 (Atonal protein homolog 5) (Helix-loop-helix protein mATH-4B) (MATH4B).

NGN2_MOUSE
NC score	0.091248 (rank : 82)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	127	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	P70447, P70237	Gene names	Neurog2, Ath4a, Atoh4, Ngn2
Domain Architecture
Description	Neurogenin 2 (Atonal protein homolog 4) (Helix-loop-helix protein mATH-4A) (MATH4A).

MYF6_HUMAN
NC score	0.090744 (rank : 83)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	127	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	P23409, Q53X80, Q6FHI9	Gene names	MYF6
Domain Architecture
Description	Myogenic factor 6 (Myf-6).

TCF15_HUMAN
NC score	0.089765 (rank : 84)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	127	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q12870, Q9NQQ1	Gene names	TCF15, BHLHEC2
Domain Architecture
Description	Transcription factor 15 (bHLH-EC2 protein) (Paraxis).

MYOG_HUMAN
NC score	0.087388 (rank : 85)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	127	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	P15173	Gene names	MYOG, MYF4
Domain Architecture
Description	Myogenin (Myogenic factor 4) (Myf-4).

MYOG_MOUSE
NC score	0.087196 (rank : 86)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	P12979	Gene names	Myog
Domain Architecture
Description	Myogenin (MYOD1-related protein).

MYF6_MOUSE
NC score	0.086669 (rank : 87)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	127	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	P15375	Gene names	Myf6, Myf-6
Domain Architecture
Description	Myogenic factor 6 (Myf-6) (Herculin).

ITF2_MOUSE
NC score	0.086380 (rank : 88)	θ value	0.279714 (rank : 56)
Query Neighborhood Hits	127	Target Neighborhood Hits	154	Shared Neighborhood Hits	23
SwissProt Accessions	Q60722, Q60721, Q62211, Q64072, Q80UE8	Gene names	Tcf4, Itf2, Sef2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (MITF-2) (SL3-3 enhancer factor 2) (SEF-2) (Class A helix-loop-helix transcription factor ME2).

ITF2_HUMAN
NC score	0.085149 (rank : 89)	θ value	0.279714 (rank : 55)
Query Neighborhood Hits	127	Target Neighborhood Hits	168	Shared Neighborhood Hits	24
SwissProt Accessions	P15884, Q15439, Q15440	Gene names	TCF4, ITF2, SEF2
Domain Architecture
Description	Transcription factor 4 (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2).

TAL2_HUMAN
NC score	0.084565 (rank : 90)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	26
SwissProt Accessions	Q16559	Gene names	TAL2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein (TAL-2 protein).

TAL2_MOUSE
NC score	0.084288 (rank : 91)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	127	Target Neighborhood Hits	79	Shared Neighborhood Hits	27
SwissProt Accessions	Q62282	Gene names	Tal2
Domain Architecture
Description	T-cell acute lymphocytic leukemia-2 protein homolog (TAL-2 protein).

MYF5_MOUSE
NC score	0.080936 (rank : 92)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	34
SwissProt Accessions	P24699, Q543W7	Gene names	Myf5, Myf-5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

BMAL1_HUMAN
NC score	0.079257 (rank : 93)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	127	Target Neighborhood Hits	115	Shared Neighborhood Hits	33
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

MYF5_HUMAN
NC score	0.078929 (rank : 94)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	34
SwissProt Accessions	P13349	Gene names	MYF5
Domain Architecture
Description	Myogenic factor 5 (Myf-5).

NDF1_MOUSE
NC score	0.078871 (rank : 95)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	127	Target Neighborhood Hits	209	Shared Neighborhood Hits	35
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

BMAL1_MOUSE
NC score	0.078797 (rank : 96)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	127	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

HTF4_HUMAN
NC score	0.078793 (rank : 97)	θ value	0.47712 (rank : 62)
Query Neighborhood Hits	127	Target Neighborhood Hits	152	Shared Neighborhood Hits	21
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

MYOD1_MOUSE
NC score	0.078046 (rank : 98)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	34
SwissProt Accessions	P10085	Gene names	Myod1, Myod
Domain Architecture
Description	Myoblast determination protein 1.

HTF4_MOUSE
NC score	0.077577 (rank : 99)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	127	Target Neighborhood Hits	153	Shared Neighborhood Hits	21
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

NDF1_HUMAN
NC score	0.077163 (rank : 100)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	127	Target Neighborhood Hits	186	Shared Neighborhood Hits	34
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

MYOD1_HUMAN
NC score	0.076824 (rank : 101)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	127	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	P15172	Gene names	MYOD1, MYF3, MYOD
Domain Architecture
Description	Myoblast determination protein 1 (Myogenic factor 3) (Myf-3).

ID4_HUMAN
NC score	0.073985 (rank : 102)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	127	Target Neighborhood Hits	67	Shared Neighborhood Hits	24
SwissProt Accessions	P47928, Q13005	Gene names	ID4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

MUSC_MOUSE
NC score	0.073664 (rank : 103)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	127	Target Neighborhood Hits	78	Shared Neighborhood Hits	26
SwissProt Accessions	O88940	Gene names	Msc, Myor
Domain Architecture
Description	Musculin (Myogenic repressor).

MUSC_HUMAN
NC score	0.072930 (rank : 104)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	127	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	O60682, O75946, Q9BRE7	Gene names	MSC, ABF1
Domain Architecture
Description	Musculin (Activated B-cell factor 1) (ABF-1).

NGN1_MOUSE
NC score	0.072773 (rank : 105)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	127	Target Neighborhood Hits	87	Shared Neighborhood Hits	26
SwissProt Accessions	P70660	Gene names	Neurog1, Ath4c, Neurod3, Ngn, Ngn1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein) (Helix-loop-helix protein mATH-4C) (MATH4C).

ID4_MOUSE
NC score	0.072338 (rank : 106)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	127	Target Neighborhood Hits	66	Shared Neighborhood Hits	24
SwissProt Accessions	P41139	Gene names	Id4, Id-4, Idb4
Domain Architecture
Description	DNA-binding protein inhibitor ID-4 (Inhibitor of DNA binding 4).

NGN1_HUMAN
NC score	0.071207 (rank : 107)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	127	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q92886, Q96HE1	Gene names	NEUROG1, NEUROD3, NGN, NGN1
Domain Architecture
Description	Neurogenin 1 (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenic basic-helix-loop-helix protein).

TCF21_HUMAN
NC score	0.069471 (rank : 108)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	127	Target Neighborhood Hits	68	Shared Neighborhood Hits	24
SwissProt Accessions	O43680, O43545, Q9BZ14	Gene names	TCF21, POD1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

TCF21_MOUSE
NC score	0.068632 (rank : 109)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	127	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	O35437, Q3U023	Gene names	Tcf21, Pod1
Domain Architecture
Description	Transcription factor 21 (Podocyte-expressed 1) (Pod-1) (Epicardin) (Capsulin).

NDF6_HUMAN
NC score	0.065808 (rank : 110)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	26
SwissProt Accessions	Q96NK8, Q9H3H6	Gene names	NEUROD6
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6).

NDF6_MOUSE
NC score	0.065618 (rank : 111)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	127	Target Neighborhood Hits	95	Shared Neighborhood Hits	26
SwissProt Accessions	P48986	Gene names	Neurod6, Ath2, Atoh2, Nex1
Domain Architecture
Description	Neurogenic differentiation factor 6 (NeuroD6) (Atonal protein homolog 2) (Helix-loop-helix protein mATH-2) (MATH2) (NEX-1 protein).

NDF4_MOUSE
NC score	0.063733 (rank : 112)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	127	Target Neighborhood Hits	105	Shared Neighborhood Hits	25
SwissProt Accessions	O09105	Gene names	Neurod4, Ath3, Atoh3
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4) (Atonal protein homolog 3) (Helix-loop-helix protein mATH-3) (MATH3).

GDIA_HUMAN
NC score	0.063529 (rank : 113)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	P31150, P50394, Q7Z2G6, Q7Z2G9, Q7Z2H5, Q7Z2I6	Gene names	GDI1, OPHN2, RABGDIA, XAP4
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (XAP-4) (Oligophrenin- 2).

ID2_HUMAN
NC score	0.063326 (rank : 114)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	127	Target Neighborhood Hits	48	Shared Neighborhood Hits	20
SwissProt Accessions	Q02363	Gene names	ID2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

NDF4_HUMAN
NC score	0.062880 (rank : 115)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	127	Target Neighborhood Hits	91	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HD90	Gene names	NEUROD4
Domain Architecture
Description	Neurogenic differentiation factor 4 (NeuroD4).

TCFL5_HUMAN
NC score	0.062617 (rank : 116)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	127	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

GDIA_MOUSE
NC score	0.060480 (rank : 117)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	127	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P50396, Q8VHM3, Q91Y71, Q96CX5	Gene names	Gdi1, Rabgdia
Domain Architecture
Description	Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1).

GDIB_MOUSE
NC score	0.060205 (rank : 118)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	127	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q61598, Q541Z9, Q8C530, Q9D8M9	Gene names	Gdi2, Gdi3
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2) (GDI-3).

GRIN1_HUMAN
NC score	0.058631 (rank : 119)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	127	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

ID2_MOUSE
NC score	0.058505 (rank : 120)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	127	Target Neighborhood Hits	47	Shared Neighborhood Hits	20
SwissProt Accessions	P41136, O88604	Gene names	Id2, Id-2, Idb2
Domain Architecture
Description	DNA-binding protein inhibitor ID-2 (Inhibitor of DNA binding 2).

TFE2_HUMAN
NC score	0.056963 (rank : 121)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	127	Target Neighborhood Hits	161	Shared Neighborhood Hits	21
SwissProt Accessions	P15923, P15883, Q14208, Q14635, Q14636, Q9UPI9	Gene names	TCF3, E2A, ITF1
Domain Architecture
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Immunoglobulin transcription factor 1) (Transcription factor ITF-1) (Kappa-E2-binding factor).

HEY2_MOUSE
NC score	0.055631 (rank : 122)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	127	Target Neighborhood Hits	80	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY2_HUMAN
NC score	0.055388 (rank : 123)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	127	Target Neighborhood Hits	77	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

TFE2_MOUSE
NC score	0.054679 (rank : 124)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	127	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	P15806, Q3U153, Q8CAH9, Q8VCY4, Q922S2, Q99MB8, Q9CYJ4	Gene names	Tcf3, Alf2, Me2, Tcfe2a
Domain Architecture	No domain graphic available
Description	Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1).

BHLH4_HUMAN
NC score	0.054284 (rank : 125)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	127	Target Neighborhood Hits	70	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDY6	Gene names	BHLHB4
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

BHLH4_MOUSE
NC score	0.054077 (rank : 126)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	127	Target Neighborhood Hits	71	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BGW3, Q71MB7	Gene names	Bhlhb4, H20
Domain Architecture	No domain graphic available
Description	Class B basic helix-loop-helix protein 4 (bHLHB4).

OLIG2_MOUSE
NC score	0.052336 (rank : 127)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	127	Target Neighborhood Hits	74	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EQW6, Q9JKN4	Gene names	Olig2
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2).

OLIG2_HUMAN
NC score	0.051870 (rank : 128)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	127	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q13516, Q86X04, Q9NZ14	Gene names	OLIG2, BHLHB1, PRKCBP2, RACK17
Domain Architecture
Description	Oligodendrocyte transcription factor 2 (Oligo2) (Basic helix-loop- helix protein class B 1) (Protein kinase C-binding protein RACK17) (Protein kinase C-binding protein 2).

GDIB_HUMAN
NC score	0.051675 (rank : 129)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	127	Target Neighborhood Hits	14	Shared Neighborhood Hits	5
SwissProt Accessions	P50395, O43928, Q9UQM6	Gene names	GDI2, RABGDIB
Domain Architecture
Description	Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2).

HEY1_MOUSE
NC score	0.051601 (rank : 130)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	127	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

BHLH3_HUMAN
NC score	0.051119 (rank : 131)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	127	Target Neighborhood Hits	106	Shared Neighborhood Hits	27
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

HEY1_HUMAN
NC score	0.050366 (rank : 132)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	127	Target Neighborhood Hits	82	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

OLIG1_HUMAN
NC score	0.050117 (rank : 133)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	127	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TAK6, Q7RTS0	Gene names	OLIG1
Domain Architecture
Description	Oligodendrocyte transcription factor 1 (Oligo1).

DEND_MOUSE
NC score	0.046402 (rank : 134)	θ value	0.21417 (rank : 51)
Query Neighborhood Hits	127	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q80TS7	Gene names	Ddn, Kiaa0749
Domain Architecture	No domain graphic available
Description	Dendrin.

ACINU_HUMAN
NC score	0.042919 (rank : 135)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	127	Target Neighborhood Hits	828	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

FGFP3_HUMAN
NC score	0.039515 (rank : 136)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	127	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAT2, Q8NBN0	Gene names	FGFBP3, C10orf13
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor-binding protein 3 precursor (FGF-binding protein 3) (FGF-BP3) (FGFBP-3).

OGFR_HUMAN
NC score	0.038704 (rank : 137)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	127	Target Neighborhood Hits	1582	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

NFH_MOUSE
NC score	0.038134 (rank : 138)	θ value	2.44474e-05 (rank : 13)
Query Neighborhood Hits	127	Target Neighborhood Hits	2247	Shared Neighborhood Hits	42
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

P80C_HUMAN
NC score	0.032952 (rank : 139)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	127	Target Neighborhood Hits	73	Shared Neighborhood Hits	5
SwissProt Accessions	P38432	Gene names	COIL, CLN80
Domain Architecture	No domain graphic available
Description	Coilin (p80).

NOL6_MOUSE
NC score	0.032562 (rank : 140)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	127	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5K4, Q6PAN8, Q8C6V4, Q8R5K3, Q8VCG0, Q8WTY7	Gene names	Nol6
Domain Architecture	No domain graphic available
Description	Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap).

CS007_MOUSE
NC score	0.031409 (rank : 141)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	127	Target Neighborhood Hits	464	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

TB182_HUMAN
NC score	0.030419 (rank : 142)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	127	Target Neighborhood Hits	414	Shared Neighborhood Hits	12
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

K0310_HUMAN
NC score	0.029809 (rank : 143)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	127	Target Neighborhood Hits	420	Shared Neighborhood Hits	17
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

EPN1_HUMAN
NC score	0.028102 (rank : 144)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	127	Target Neighborhood Hits	206	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6I3, Q86ST3, Q9HA18	Gene names	EPN1
Domain Architecture
Description	Epsin-1 (EPS-15-interacting protein 1) (EH domain-binding mitotic phosphoprotein).

EPN3_MOUSE
NC score	0.027184 (rank : 145)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	127	Target Neighborhood Hits	312	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W69, Q9CV55	Gene names	Epn3
Domain Architecture
Description	Epsin-3 (EPS-15-interacting protein 3).

SPIB_MOUSE
NC score	0.027163 (rank : 146)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	127	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	O35906, O35907, O35909, O55199	Gene names	Spib
Domain Architecture	No domain graphic available
Description	Transcription factor Spi-B.

IWS1_MOUSE
NC score	0.026337 (rank : 147)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	127	Target Neighborhood Hits	1258	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SDPR_MOUSE
NC score	0.025945 (rank : 148)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	127	Target Neighborhood Hits	485	Shared Neighborhood Hits	13
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

CUTL1_HUMAN
NC score	0.023569 (rank : 149)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	127	Target Neighborhood Hits	1574	Shared Neighborhood Hits	29
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
NC score	0.022399 (rank : 150)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	127	Target Neighborhood Hits	1620	Shared Neighborhood Hits	25
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

SRRM2_MOUSE
NC score	0.021151 (rank : 151)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	127	Target Neighborhood Hits	1470	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CASP_MOUSE
NC score	0.020284 (rank : 152)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	127	Target Neighborhood Hits	1152	Shared Neighborhood Hits	15
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
NC score	0.019595 (rank : 153)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	127	Target Neighborhood Hits	1131	Shared Neighborhood Hits	18
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

IRS2_MOUSE
NC score	0.018518 (rank : 154)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	127	Target Neighborhood Hits	248	Shared Neighborhood Hits	14
SwissProt Accessions	P81122	Gene names	Irs2
Domain Architecture	No domain graphic available
Description	Insulin receptor substrate 2 (IRS-2) (4PS).

PCLO_MOUSE
NC score	0.016560 (rank : 155)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	127	Target Neighborhood Hits	2275	Shared Neighborhood Hits	42
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

OSBP2_HUMAN
NC score	0.015762 (rank : 156)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	127	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

RHG05_HUMAN
NC score	0.015626 (rank : 157)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	127	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

CDS1_HUMAN
NC score	0.015286 (rank : 158)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	127	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

RHG05_MOUSE
NC score	0.015180 (rank : 159)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	127	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

SMC4_HUMAN
NC score	0.014867 (rank : 160)	θ value	2.36792 (rank : 87)
Query Neighborhood Hits	127	Target Neighborhood Hits	937	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

ATS13_HUMAN
NC score	0.014809 (rank : 161)	θ value	0.21417 (rank : 50)
Query Neighborhood Hits	127	Target Neighborhood Hits	238	Shared Neighborhood Hits	6
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

WASF2_HUMAN
NC score	0.014698 (rank : 162)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	127	Target Neighborhood Hits	280	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6W5, O60794, Q9UDY7	Gene names	WASF2, WAVE2
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 2 (WASP-family protein member 2) (Protein WAVE-2) (Verprolin homology domain-containing protein 2).

PHLPP_HUMAN
NC score	0.014047 (rank : 163)	θ value	1.81305 (rank : 81)
Query Neighborhood Hits	127	Target Neighborhood Hits	604	Shared Neighborhood Hits	14
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

TRIPB_HUMAN
NC score	0.013853 (rank : 164)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	127	Target Neighborhood Hits	1587	Shared Neighborhood Hits	28
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

MYH6_HUMAN
NC score	0.013277 (rank : 165)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	127	Target Neighborhood Hits	1426	Shared Neighborhood Hits	19
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
NC score	0.013213 (rank : 166)	θ value	2.36792 (rank : 85)
Query Neighborhood Hits	127	Target Neighborhood Hits	1559	Shared Neighborhood Hits	20
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PEPL_MOUSE
NC score	0.012843 (rank : 167)	θ value	2.36792 (rank : 86)
Query Neighborhood Hits	127	Target Neighborhood Hits	1105	Shared Neighborhood Hits	21
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

MYH6_MOUSE
NC score	0.012532 (rank : 168)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	127	Target Neighborhood Hits	1501	Shared Neighborhood Hits	22
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CO002_HUMAN
NC score	0.012487 (rank : 169)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	127	Target Neighborhood Hits	387	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

NPM2_MOUSE
NC score	0.012090 (rank : 170)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	127	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q80W85, Q8BW23	Gene names	Npm2
Domain Architecture
Description	Nucleoplasmin-2.

ETV3_HUMAN
NC score	0.011677 (rank : 171)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	127	Target Neighborhood Hits	312	Shared Neighborhood Hits	11
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

IL16_HUMAN
NC score	0.011426 (rank : 172)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	127	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q14005, Q16435, Q9UP18	Gene names	IL16
Domain Architecture
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

PTN13_MOUSE
NC score	0.010609 (rank : 173)	θ value	0.279714 (rank : 57)
Query Neighborhood Hits	127	Target Neighborhood Hits	426	Shared Neighborhood Hits	5
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

CEL_HUMAN
NC score	0.009512 (rank : 174)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	127	Target Neighborhood Hits	896	Shared Neighborhood Hits	21
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

CSKI1_MOUSE
NC score	0.008247 (rank : 175)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	127	Target Neighborhood Hits	1031	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FOG1_MOUSE
NC score	0.008176 (rank : 176)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	127	Target Neighborhood Hits	1237	Shared Neighborhood Hits	23
SwissProt Accessions	O35615	Gene names	Zfpm1, Fog, Fog1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

MAGD4_HUMAN
NC score	0.006184 (rank : 177)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	127	Target Neighborhood Hits	338	Shared Neighborhood Hits	15
SwissProt Accessions	Q96JG8, Q8WXW4, Q9BQ84, Q9BYH3, Q9BYH4	Gene names	MAGED4, KIAA1859, MAGEE1
Domain Architecture
Description	Melanoma-associated antigen D4 (MAGE-D4 antigen) (MAGE-E1 antigen).

POT15_HUMAN
NC score	0.003741 (rank : 178)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	127	Target Neighborhood Hits	893	Shared Neighborhood Hits	16
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TTBK2_MOUSE
NC score	0.003709 (rank : 179)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	127	Target Neighborhood Hits	811	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UVR3, Q3TSR6, Q3UFW0, Q571D1, Q8BKA4, Q924U8	Gene names	Ttbk2, Kiaa0847, Ttbk1
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2.

TTBK2_HUMAN
NC score	0.003334 (rank : 180)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	127	Target Neighborhood Hits	822	Shared Neighborhood Hits	12
SwissProt Accessions	Q6IQ55, O94932, Q6ZN52, Q8IVV1	Gene names	TTBK2, KIAA0847
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 2 (EC 2.7.11.1).

SALL4_HUMAN
NC score	0.001791 (rank : 181)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	127	Target Neighborhood Hits	799	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJQ4	Gene names	SALL4
Domain Architecture
Description	Sal-like protein 4 (Zinc finger protein SALL4).

HXB3_MOUSE
NC score	0.001649 (rank : 182)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	127	Target Neighborhood Hits	493	Shared Neighborhood Hits	6
SwissProt Accessions	P09026, P10285, Q4PJ06, Q61680	Gene names	Hoxb3, Hox-2.7, Hoxb-3
Domain Architecture
Description	Homeobox protein Hox-B3 (Hox-2.7) (Homeobox protein MH-23).

SALL1_MOUSE
NC score	0.001315 (rank : 183)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	127	Target Neighborhood Hits	826	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ER74, Q920R5	Gene names	Sall1, Sal3
Domain Architecture
Description	Sal-like protein 1 (Zinc finger protein Spalt-3) (Sal-3) (MSal-3).

ZN142_HUMAN
NC score	0.000066 (rank : 184)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	127	Target Neighborhood Hits	1007	Shared Neighborhood Hits	14
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

CAMKV_HUMAN
NC score	-0.000340 (rank : 185)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	127	Target Neighborhood Hits	1084	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCB2, Q6FIB8, Q8NBS8, Q8NC85, Q8NDU4, Q8WTT8, Q9BQC9, Q9H0Q5	Gene names	CAMKV
Domain Architecture	No domain graphic available
Description	CaM kinase-like vesicle-associated protein.

ZFP28_HUMAN
NC score	-0.000950 (rank : 186)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	127	Target Neighborhood Hits	843	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

ZN275_HUMAN
NC score	-0.002311 (rank : 187)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	127	Target Neighborhood Hits	761	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NSD4	Gene names	ZNF275
Domain Architecture	No domain graphic available
Description	Zinc finger protein 275.