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Network neighborhood for query Sequence : CDS1_HUMAN

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CDS1_HUMAN
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CDS1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CDS1_MOUSE
θ value	0 (rank : 2)	NC score	0.998472 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P98191, Q8CGZ1	Gene names	Cds1, Cds
Domain Architecture	No domain graphic available
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CDS2_HUMAN
θ value	0 (rank : 3)	NC score	0.993134 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	O95674, Q5TDY2, Q5TDY3, Q5TDY4, Q5TDY5, Q9BYK5, Q9NTT2	Gene names	CDS2
Domain Architecture
Description	Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-diglyceride synthetase 2) (CDP-diglyceride pyrophosphorylase 2) (CDP- diacylglycerol synthase 2) (CDS 2) (CTP:phosphatidate cytidylyltransferase 2) (CDP-DAG synthase 2) (CDP-DG synthetase 2).

CDS2_MOUSE
θ value	0 (rank : 4)	NC score	0.993455 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q99L43, Q3TMD1, Q6NSU1	Gene names	Cds2
Domain Architecture	No domain graphic available
Description	Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-diglyceride synthetase 2) (CDP-diglyceride pyrophosphorylase 2) (CDP- diacylglycerol synthase 2) (CDS 2) (CTP:phosphatidate cytidylyltransferase 2) (CDP-DAG synthase 2) (CDP-DG synthetase 2).

G109A_HUMAN
θ value	0.125558 (rank : 5)	NC score	0.035141 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	614	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDS4	Gene names	GPR109A, HM74A
Domain Architecture	No domain graphic available
Description	Nicotinic acid receptor 1 (G-protein coupled receptor 109A) (G-protein coupled receptor HM74A).

G109B_HUMAN
θ value	0.125558 (rank : 6)	NC score	0.038271 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	579	Shared Neighborhood Hits	6
SwissProt Accessions	P49019, Q8NGE4	Gene names	GPR109B
Domain Architecture
Description	Nicotinic acid receptor 2 (G-protein coupled receptor 109B) (G-protein coupled receptor HM74) (G-protein coupled receptor HM74B).

CN103_MOUSE
θ value	0.813845 (rank : 7)	NC score	0.032682 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XK6, Q8R1H5, Q9CWK6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf103 homolog.

RP1L1_HUMAN
θ value	1.81305 (rank : 8)	NC score	0.012768 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	1072	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MYCN_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.015286 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

CYB5_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.019862 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P00167	Gene names	CYB5
Domain Architecture
Description	Cytochrome b5.

CTL2_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.017907 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWA5, Q658V1, Q658Z2, Q6PJV7, Q8N2F0, Q9NY68	Gene names	SLC44A2, CTL2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

CTL2_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.026732 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BY89, Q8K2F1	Gene names	Slc44a2, Ctl2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

IL3B2_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.015203 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	372	Shared Neighborhood Hits	3
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

RIMS2_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.006389 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	376	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

DRAP1_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.013676 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

SET1A_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.006016 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	690	Shared Neighborhood Hits	2
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

Hits sorted by NC score

CDS1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CDS1_MOUSE
NC score	0.998472 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P98191, Q8CGZ1	Gene names	Cds1, Cds
Domain Architecture	No domain graphic available
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

CDS2_MOUSE
NC score	0.993455 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	Q99L43, Q3TMD1, Q6NSU1	Gene names	Cds2
Domain Architecture	No domain graphic available
Description	Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-diglyceride synthetase 2) (CDP-diglyceride pyrophosphorylase 2) (CDP- diacylglycerol synthase 2) (CDS 2) (CTP:phosphatidate cytidylyltransferase 2) (CDP-DAG synthase 2) (CDP-DG synthetase 2).

CDS2_HUMAN
NC score	0.993134 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	O95674, Q5TDY2, Q5TDY3, Q5TDY4, Q5TDY5, Q9BYK5, Q9NTT2	Gene names	CDS2
Domain Architecture
Description	Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-diglyceride synthetase 2) (CDP-diglyceride pyrophosphorylase 2) (CDP- diacylglycerol synthase 2) (CDS 2) (CTP:phosphatidate cytidylyltransferase 2) (CDP-DAG synthase 2) (CDP-DG synthetase 2).

G109B_HUMAN
NC score	0.038271 (rank : 5)	θ value	0.125558 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	579	Shared Neighborhood Hits	6
SwissProt Accessions	P49019, Q8NGE4	Gene names	GPR109B
Domain Architecture
Description	Nicotinic acid receptor 2 (G-protein coupled receptor 109B) (G-protein coupled receptor HM74) (G-protein coupled receptor HM74B).

G109A_HUMAN
NC score	0.035141 (rank : 6)	θ value	0.125558 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	614	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDS4	Gene names	GPR109A, HM74A
Domain Architecture	No domain graphic available
Description	Nicotinic acid receptor 1 (G-protein coupled receptor 109A) (G-protein coupled receptor HM74A).

CN103_MOUSE
NC score	0.032682 (rank : 7)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XK6, Q8R1H5, Q9CWK6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf103 homolog.

CTL2_MOUSE
NC score	0.026732 (rank : 8)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BY89, Q8K2F1	Gene names	Slc44a2, Ctl2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

CYB5_HUMAN
NC score	0.019862 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P00167	Gene names	CYB5
Domain Architecture
Description	Cytochrome b5.

CTL2_HUMAN
NC score	0.017907 (rank : 10)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IWA5, Q658V1, Q658Z2, Q6PJV7, Q8N2F0, Q9NY68	Gene names	SLC44A2, CTL2
Domain Architecture	No domain graphic available
Description	Choline transporter-like protein 2 (Solute carrier family 44 member 2).

MYCN_HUMAN
NC score	0.015286 (rank : 11)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	127	Shared Neighborhood Hits	2
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

IL3B2_MOUSE
NC score	0.015203 (rank : 12)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	372	Shared Neighborhood Hits	3
SwissProt Accessions	P26954	Gene names	Csf2rb2, Ai2ca, Il3r, Il3rb2
Domain Architecture
Description	Interleukin-3 receptor class 2 beta chain precursor (Interleukin-3 receptor class II beta chain) (Colony-stimulating factor 2 receptor, beta 2 chain).

DRAP1_MOUSE
NC score	0.013676 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

RP1L1_HUMAN
NC score	0.012768 (rank : 14)	θ value	1.81305 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	1072	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

RIMS2_MOUSE
NC score	0.006389 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	376	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EQZ7, Q8C433, Q8CCK2	Gene names	Rims2, Rab3ip2, Rim2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2) (Rab3-interacting protein 2).

SET1A_HUMAN
NC score	0.006016 (rank : 16)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	690	Shared Neighborhood Hits	2
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).