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Network neighborhood for query Sequence : DRAP1_MOUSE

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DRAP1_MOUSE
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DRAP1_MOUSE
θ value	5.00389e-67 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DRAP1_HUMAN
θ value	4.10295e-61 (rank : 2)	NC score	0.980365 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

NFYC_HUMAN
θ value	1.17247e-07 (rank : 3)	NC score	0.533698 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

NFYC_MOUSE
θ value	1.17247e-07 (rank : 4)	NC score	0.572987 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

DPOE4_HUMAN
θ value	0.000158464 (rank : 5)	NC score	0.513292 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

DPOE4_MOUSE
θ value	0.000158464 (rank : 6)	NC score	0.514637 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQ36, Q3TJ13	Gene names	Pole4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

CHRC1_HUMAN
θ value	0.00869519 (rank : 7)	NC score	0.405346 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

CHRC1_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.370188 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKP8, Q91VG2	Gene names	Chrac1
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (YC-like protein 1) (YCL1) (NF-YC-like protein).

IWS1_MOUSE
θ value	0.125558 (rank : 9)	NC score	0.064680 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	1258	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

H2A1A_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.224108 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q96QV6	Gene names	HIST1H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-A.

H2AX_HUMAN
θ value	0.47712 (rank : 11)	NC score	0.221753 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P16104, Q4ZGJ7, Q6IAS5	Gene names	H2AFX, H2AX
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AX_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.220979 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P27661	Gene names	H2afx, H2a.x, H2ax, Hist5-2ax
Domain Architecture
Description	Histone H2A.x (H2a/x).

DEN2A_HUMAN
θ value	0.62314 (rank : 13)	NC score	0.032357 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

H2A1C_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.220020 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q93077, O00775, O00776, O00777, O00778, Q540R1	Gene names	HIST1H2AC, H2AFL
Domain Architecture
Description	Histone H2A type 1-C.

H2A2A_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.219854 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).

H2A2A_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.219854 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q6GSS7, P20670, Q811M3	Gene names	Hist2h2aa1
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2) (H2a-614) (H2a-615).

H2A2B_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.219448 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUE6	Gene names	HIST2H2AB
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B.

H2A2C_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.219798 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q16777, Q6DRA7, Q8IUE5	Gene names	HIST2H2AC, H2AFQ
Domain Architecture
Description	Histone H2A type 2-C (H2A-GL101) (H2A/r).

H2A2C_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.219798 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q64523, Q8CGP3	Gene names	Hist2h2ac, Hist2h2ab
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-C (H2a-613B).

H2A2B_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.217959 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q64522	Gene names
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B (H2a-613A).

H2A3_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.215768 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L7L0	Gene names	HIST3H2A
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A3_MOUSE
θ value	0.813845 (rank : 22)	NC score	0.215768 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFU2	Gene names	Hist3h2a
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

ZRF1_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.034497 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	457	Shared Neighborhood Hits	4
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

H2A1H_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.217291 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q96KK5	Gene names	HIST1H2AH, HIST1H2AI
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1J_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.217259 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q99878, Q5JXQ5	Gene names	HIST1H2AJ, H2AFE
Domain Architecture
Description	Histone H2A type 1-J.

H2A1_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.217383 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P0C0S8, P02261, Q2M1R2, Q76PA6	Gene names	HIST1H2AG, H2AFP
Domain Architecture	No domain graphic available
Description	Histone H2A type 1 (H2A.1).

H2A1D_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.213088 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P20671, P57754, Q6FGY6	Gene names	HIST1H2AD, H2AFG
Domain Architecture
Description	Histone H2A type 1-D (H2A.3).

H2A1E_HUMAN
θ value	1.81305 (rank : 28)	NC score	0.211729 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P28001, Q76P63	Gene names	HIST1H2AE, H2AFA
Domain Architecture
Description	Histone H2A type 1-E (H2A.2) (H2A/m).

H2A1F_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.211715 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGP5	Gene names	Hist1h2af
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-F.

H2A1H_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.211607 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGP6	Gene names	Hist1h2ah
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1K_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.211646 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGP7	Gene names	Hist1h2ak
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-K.

H2A1_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.211729 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P22752, P10812, Q5SZZ2	Gene names	Hist1h2ab
Domain Architecture
Description	Histone H2A type 1.

H2A1B_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.210081 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	P04908	Gene names	HIST1H2AB, H2AFM
Domain Architecture
Description	Histone H2A type 1-B.

IWS1_HUMAN
θ value	2.36792 (rank : 34)	NC score	0.048440 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PSMD2_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.035038 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

TSP3_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.018931 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

ACK1_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.003121 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	1140	Shared Neighborhood Hits	7
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

AKTS1_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.042721 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q96B36, Q96BI4, Q96IK7, Q96NG2, Q9BWR5	Gene names	AKT1S1, PRAS40
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate).

TARA_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.024671 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TACC1_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.018995 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	667	Shared Neighborhood Hits	8
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

FBX34_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.022513 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

CBL_MOUSE
θ value	6.88961 (rank : 42)	NC score	0.024309 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	426	Shared Neighborhood Hits	5
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CD017_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.031850 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

EP15_HUMAN
θ value	6.88961 (rank : 44)	NC score	0.006990 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	1021	Shared Neighborhood Hits	7
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

OXRP_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.014740 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	544	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PLEC1_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.004049 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	1326	Shared Neighborhood Hits	6
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SEM4D_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.011536 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

TARA_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.023132 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	1133	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

XRCC1_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.028086 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

CBL_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.019727 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	353	Shared Neighborhood Hits	5
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBPD_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.009203 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CDS1_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.013676 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

DCDC2_MOUSE
θ value	8.99809 (rank : 53)	NC score	0.016328 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

MAGE1_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.005070 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	1389	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAP1B_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.024106 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	977	Shared Neighborhood Hits	11
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

SIP1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.003298 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
θ value	8.99809 (rank : 57)	NC score	0.003125 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	870	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

TOP2A_MOUSE
θ value	8.99809 (rank : 58)	NC score	0.012566 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TRIM9_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.009361 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TSP3_MOUSE
θ value	8.99809 (rank : 60)	NC score	0.015927 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

H2AFB_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.187193 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P98176, Q5TZB2, Q6FG78, Q96PR7	Gene names	H2AFB3, H2ABBD, H2AFB
Domain Architecture
Description	Histone H2A-Bbd (H2A Barr body-deficient) (H2A.Bbd).

H2AV_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.176208 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q71UI9, Q59GV8, Q6PK98	Gene names	H2AFV, H2AV
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AV_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.176208 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q3THW5, Q5NC92, Q6ZWU0	Gene names	H2afv, H2av
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AW_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.163034 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.163193 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.159685 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	48	Shared Neighborhood Hits	22
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.159733 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AZ_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.176229 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	P0C0S5, P17317, Q6I9U0	Gene names	H2AFZ, H2AZ
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AZ_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.176229 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	P0C0S6, P17317, Q3UA55, Q3UK43, Q68FD2	Gene names	H2afz, H2az
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

SOS1_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.051020 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	26
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS1_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.054859 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	281	Shared Neighborhood Hits	28
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

Hits sorted by NC score

DRAP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	5.00389e-67 (rank : 1)
Query Neighborhood Hits	60	Target Neighborhood Hits	60	Shared Neighborhood Hits	60
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DRAP1_HUMAN
NC score	0.980365 (rank : 2)	θ value	4.10295e-61 (rank : 2)
Query Neighborhood Hits	60	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

NFYC_MOUSE
NC score	0.572987 (rank : 3)	θ value	1.17247e-07 (rank : 4)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

NFYC_HUMAN
NC score	0.533698 (rank : 4)	θ value	1.17247e-07 (rank : 3)
Query Neighborhood Hits	60	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

DPOE4_MOUSE
NC score	0.514637 (rank : 5)	θ value	0.000158464 (rank : 6)
Query Neighborhood Hits	60	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQ36, Q3TJ13	Gene names	Pole4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

DPOE4_HUMAN
NC score	0.513292 (rank : 6)	θ value	0.000158464 (rank : 5)
Query Neighborhood Hits	60	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

CHRC1_HUMAN
NC score	0.405346 (rank : 7)	θ value	0.00869519 (rank : 7)
Query Neighborhood Hits	60	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

CHRC1_MOUSE
NC score	0.370188 (rank : 8)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	60	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JKP8, Q91VG2	Gene names	Chrac1
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (YC-like protein 1) (YCL1) (NF-YC-like protein).

H2A1A_HUMAN
NC score	0.224108 (rank : 9)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q96QV6	Gene names	HIST1H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-A.

H2AX_HUMAN
NC score	0.221753 (rank : 10)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P16104, Q4ZGJ7, Q6IAS5	Gene names	H2AFX, H2AX
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AX_MOUSE
NC score	0.220979 (rank : 11)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P27661	Gene names	H2afx, H2a.x, H2ax, Hist5-2ax
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2A1C_HUMAN
NC score	0.220020 (rank : 12)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q93077, O00775, O00776, O00777, O00778, Q540R1	Gene names	HIST1H2AC, H2AFL
Domain Architecture
Description	Histone H2A type 1-C.

H2A2A_HUMAN
NC score	0.219854 (rank : 13)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).

H2A2A_MOUSE
NC score	0.219854 (rank : 14)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q6GSS7, P20670, Q811M3	Gene names	Hist2h2aa1
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2) (H2a-614) (H2a-615).

H2A2C_HUMAN
NC score	0.219798 (rank : 15)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q16777, Q6DRA7, Q8IUE5	Gene names	HIST2H2AC, H2AFQ
Domain Architecture
Description	Histone H2A type 2-C (H2A-GL101) (H2A/r).

H2A2C_MOUSE
NC score	0.219798 (rank : 16)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q64523, Q8CGP3	Gene names	Hist2h2ac, Hist2h2ab
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-C (H2a-613B).

H2A2B_HUMAN
NC score	0.219448 (rank : 17)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IUE6	Gene names	HIST2H2AB
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B.

H2A2B_MOUSE
NC score	0.217959 (rank : 18)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q64522	Gene names
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B (H2a-613A).

H2A1_HUMAN
NC score	0.217383 (rank : 19)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	P0C0S8, P02261, Q2M1R2, Q76PA6	Gene names	HIST1H2AG, H2AFP
Domain Architecture	No domain graphic available
Description	Histone H2A type 1 (H2A.1).

H2A1H_HUMAN
NC score	0.217291 (rank : 20)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q96KK5	Gene names	HIST1H2AH, HIST1H2AI
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1J_HUMAN
NC score	0.217259 (rank : 21)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	26
SwissProt Accessions	Q99878, Q5JXQ5	Gene names	HIST1H2AJ, H2AFE
Domain Architecture
Description	Histone H2A type 1-J.

H2A3_HUMAN
NC score	0.215768 (rank : 22)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q7L7L0	Gene names	HIST3H2A
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A3_MOUSE
NC score	0.215768 (rank : 23)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFU2	Gene names	Hist3h2a
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A1D_HUMAN
NC score	0.213088 (rank : 24)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P20671, P57754, Q6FGY6	Gene names	HIST1H2AD, H2AFG
Domain Architecture
Description	Histone H2A type 1-D (H2A.3).

H2A1E_HUMAN
NC score	0.211729 (rank : 25)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P28001, Q76P63	Gene names	HIST1H2AE, H2AFA
Domain Architecture
Description	Histone H2A type 1-E (H2A.2) (H2A/m).

H2A1_MOUSE
NC score	0.211729 (rank : 26)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	P22752, P10812, Q5SZZ2	Gene names	Hist1h2ab
Domain Architecture
Description	Histone H2A type 1.

H2A1F_MOUSE
NC score	0.211715 (rank : 27)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGP5	Gene names	Hist1h2af
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-F.

H2A1K_MOUSE
NC score	0.211646 (rank : 28)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGP7	Gene names	Hist1h2ak
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-K.

H2A1H_MOUSE
NC score	0.211607 (rank : 29)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	60	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CGP6	Gene names	Hist1h2ah
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1B_HUMAN
NC score	0.210081 (rank : 30)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	60	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	P04908	Gene names	HIST1H2AB, H2AFM
Domain Architecture
Description	Histone H2A type 1-B.

H2AFB_HUMAN
NC score	0.187193 (rank : 31)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	60	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P98176, Q5TZB2, Q6FG78, Q96PR7	Gene names	H2AFB3, H2ABBD, H2AFB
Domain Architecture
Description	Histone H2A-Bbd (H2A Barr body-deficient) (H2A.Bbd).

H2AZ_HUMAN
NC score	0.176229 (rank : 32)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	P0C0S5, P17317, Q6I9U0	Gene names	H2AFZ, H2AZ
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AZ_MOUSE
NC score	0.176229 (rank : 33)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	P0C0S6, P17317, Q3UA55, Q3UK43, Q68FD2	Gene names	H2afz, H2az
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AV_HUMAN
NC score	0.176208 (rank : 34)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q71UI9, Q59GV8, Q6PK98	Gene names	H2AFV, H2AV
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AV_MOUSE
NC score	0.176208 (rank : 35)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	60	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q3THW5, Q5NC92, Q6ZWU0	Gene names	H2afv, H2av
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AW_MOUSE
NC score	0.163193 (rank : 36)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	60	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_HUMAN
NC score	0.163034 (rank : 37)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	60	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_MOUSE
NC score	0.159733 (rank : 38)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	60	Target Neighborhood Hits	49	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AY_HUMAN
NC score	0.159685 (rank : 39)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	60	Target Neighborhood Hits	48	Shared Neighborhood Hits	22
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

IWS1_MOUSE
NC score	0.064680 (rank : 40)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	60	Target Neighborhood Hits	1258	Shared Neighborhood Hits	17
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SOS1_MOUSE
NC score	0.054859 (rank : 41)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	60	Target Neighborhood Hits	281	Shared Neighborhood Hits	28
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS1_HUMAN
NC score	0.051020 (rank : 42)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	26
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

IWS1_HUMAN
NC score	0.048440 (rank : 43)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	60	Target Neighborhood Hits	1241	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

AKTS1_HUMAN
NC score	0.042721 (rank : 44)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	60	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q96B36, Q96BI4, Q96IK7, Q96NG2, Q9BWR5	Gene names	AKT1S1, PRAS40
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate).

PSMD2_MOUSE
NC score	0.035038 (rank : 45)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	60	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VDM4	Gene names	Psmd2
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 2 (26S proteasome regulatory subunit RPN1) (26S proteasome regulatory subunit S2) (26S proteasome subunit p97).

ZRF1_HUMAN
NC score	0.034497 (rank : 46)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	60	Target Neighborhood Hits	457	Shared Neighborhood Hits	4
SwissProt Accessions	Q99543	Gene names	ZRF1, DNAJC2, MPHOSPH11, MPP11
Domain Architecture
Description	Zuotin-related factor 1 (M-phase phosphoprotein 11).

DEN2A_HUMAN
NC score	0.032357 (rank : 47)	θ value	0.62314 (rank : 13)
Query Neighborhood Hits	60	Target Neighborhood Hits	83	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULE3, Q1RMD5, Q86XY0	Gene names	DENND2A, KIAA1277
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2A.

CD017_HUMAN
NC score	0.031850 (rank : 48)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	60	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	Q53FE4, Q6FI84, Q6IS77, Q9H0D9	Gene names	C4orf17
Domain Architecture	No domain graphic available
Description	Protein C4orf17.

XRCC1_HUMAN
NC score	0.028086 (rank : 49)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	60	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	P18887, Q9HCB1	Gene names	XRCC1
Domain Architecture
Description	DNA-repair protein XRCC1 (X-ray repair cross-complementing protein 1).

TARA_HUMAN
NC score	0.024671 (rank : 50)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	60	Target Neighborhood Hits	1626	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CBL_MOUSE
NC score	0.024309 (rank : 51)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	60	Target Neighborhood Hits	426	Shared Neighborhood Hits	5
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

MAP1B_MOUSE
NC score	0.024106 (rank : 52)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	60	Target Neighborhood Hits	977	Shared Neighborhood Hits	11
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TARA_MOUSE
NC score	0.023132 (rank : 53)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	60	Target Neighborhood Hits	1133	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FBX34_MOUSE
NC score	0.022513 (rank : 54)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	60	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI1, Q9D290	Gene names	Fbxo34
Domain Architecture	No domain graphic available
Description	F-box only protein 34.

CBL_HUMAN
NC score	0.019727 (rank : 55)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	60	Target Neighborhood Hits	353	Shared Neighborhood Hits	5
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

TACC1_MOUSE
NC score	0.018995 (rank : 56)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	60	Target Neighborhood Hits	667	Shared Neighborhood Hits	8
SwissProt Accessions	Q6Y685, Q6Y686	Gene names	Tacc1
Domain Architecture	No domain graphic available
Description	Transforming acidic coiled-coil-containing protein 1.

TSP3_HUMAN
NC score	0.018931 (rank : 57)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	60	Target Neighborhood Hits	250	Shared Neighborhood Hits	4
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

DCDC2_MOUSE
NC score	0.016328 (rank : 58)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	60	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

TSP3_MOUSE
NC score	0.015927 (rank : 59)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	60	Target Neighborhood Hits	247	Shared Neighborhood Hits	4
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

OXRP_HUMAN
NC score	0.014740 (rank : 60)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	60	Target Neighborhood Hits	544	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

CDS1_HUMAN
NC score	0.013676 (rank : 61)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	60	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q92903, O00163	Gene names	CDS1, CDS
Domain Architecture
Description	Phosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-diglyceride synthetase 1) (CDP-diglyceride pyrophosphorylase 1) (CDP- diacylglycerol synthase 1) (CDS 1) (CTP:phosphatidate cytidylyltransferase 1) (CDP-DAG synthase 1) (CDP-DG synthetase 1).

TOP2A_MOUSE
NC score	0.012566 (rank : 62)	θ value	8.99809 (rank : 58)
Query Neighborhood Hits	60	Target Neighborhood Hits	101	Shared Neighborhood Hits	3
SwissProt Accessions	Q01320	Gene names	Top2a, Top-2, Top2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

SEM4D_MOUSE
NC score	0.011536 (rank : 63)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	60	Target Neighborhood Hits	143	Shared Neighborhood Hits	3
SwissProt Accessions	O09126	Gene names	Sema4d, Semacl2, Semaj
Domain Architecture
Description	Semaphorin-4D precursor (Semaphorin J) (Sema J) (Semaphorin C-like 2) (M-Sema G).

TRIM9_MOUSE
NC score	0.009361 (rank : 64)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	60	Target Neighborhood Hits	274	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

CBPD_MOUSE
NC score	0.009203 (rank : 65)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	60	Target Neighborhood Hits	62	Shared Neighborhood Hits	2
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

EP15_HUMAN
NC score	0.006990 (rank : 66)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	60	Target Neighborhood Hits	1021	Shared Neighborhood Hits	7
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

MAGE1_HUMAN
NC score	0.005070 (rank : 67)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	60	Target Neighborhood Hits	1389	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PLEC1_HUMAN
NC score	0.004049 (rank : 68)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	60	Target Neighborhood Hits	1326	Shared Neighborhood Hits	6
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SIP1_HUMAN
NC score	0.003298 (rank : 69)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	60	Target Neighborhood Hits	832	Shared Neighborhood Hits	6
SwissProt Accessions	O60315, Q9UED1	Gene names	ZFHX1B, KIAA0569, SIP1, ZFX1B
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1) (SMADIP1).

SIP1_MOUSE
NC score	0.003125 (rank : 70)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	60	Target Neighborhood Hits	870	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0G7	Gene names	Zfhx1b, Sip1, Zfx1b
Domain Architecture
Description	Zinc finger homeobox protein 1b (Smad-interacting protein 1).

ACK1_HUMAN
NC score	0.003121 (rank : 71)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	60	Target Neighborhood Hits	1140	Shared Neighborhood Hits	7
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).