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Network neighborhood for query Sequence : DPOE4_HUMAN

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DPOE4_HUMAN
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOE4_HUMAN
θ value	3.26607e-42 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

DPOE4_MOUSE
θ value	6.81017e-40 (rank : 2)	NC score	0.997276 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQ36, Q3TJ13	Gene names	Pole4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

NFYC_HUMAN
θ value	3.29651e-10 (rank : 3)	NC score	0.681587 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

NFYC_MOUSE
θ value	3.29651e-10 (rank : 4)	NC score	0.728018 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

CHRC1_HUMAN
θ value	6.87365e-08 (rank : 5)	NC score	0.696595 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

CHRC1_MOUSE
θ value	1.69304e-06 (rank : 6)	NC score	0.680208 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKP8, Q91VG2	Gene names	Chrac1
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (YC-like protein 1) (YCL1) (NF-YC-like protein).

DRAP1_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.521430 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DRAP1_MOUSE
θ value	0.000158464 (rank : 8)	NC score	0.513292 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DPOE3_MOUSE
θ value	0.0736092 (rank : 9)	NC score	0.232923 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JKP7, Q8R198	Gene names	Pole3
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (YB-like protein 1) (YBL1) (NF-YB-like protein).

DPOE3_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.224953 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRF9, Q5W0U1, Q8N758, Q8NCE5, Q9NR32	Gene names	POLE3, CHRAC17
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (Chromatin accessibility complex 17) (HuCHRAC17) (CHRAC-17) (Arsenic- transactivated protein) (AsTP).

MRCKB_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.001766 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	2239	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NFYB_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.054019 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P25208, Q96IY8	Gene names	NFYB, HAP3
Domain Architecture
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

NFYB_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.050810 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P63139, P22569, Q3UK54	Gene names	Nfyb
Domain Architecture	No domain graphic available
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

Hits sorted by NC score

DPOE4_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.26607e-42 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

DPOE4_MOUSE
NC score	0.997276 (rank : 2)	θ value	6.81017e-40 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQ36, Q3TJ13	Gene names	Pole4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

NFYC_MOUSE
NC score	0.728018 (rank : 3)	θ value	3.29651e-10 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

CHRC1_HUMAN
NC score	0.696595 (rank : 4)	θ value	6.87365e-08 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

NFYC_HUMAN
NC score	0.681587 (rank : 5)	θ value	3.29651e-10 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

CHRC1_MOUSE
NC score	0.680208 (rank : 6)	θ value	1.69304e-06 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKP8, Q91VG2	Gene names	Chrac1
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (YC-like protein 1) (YCL1) (NF-YC-like protein).

DRAP1_HUMAN
NC score	0.521430 (rank : 7)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DRAP1_MOUSE
NC score	0.513292 (rank : 8)	θ value	0.000158464 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DPOE3_MOUSE
NC score	0.232923 (rank : 9)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JKP7, Q8R198	Gene names	Pole3
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (YB-like protein 1) (YBL1) (NF-YB-like protein).

DPOE3_HUMAN
NC score	0.224953 (rank : 10)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NRF9, Q5W0U1, Q8N758, Q8NCE5, Q9NR32	Gene names	POLE3, CHRAC17
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (Chromatin accessibility complex 17) (HuCHRAC17) (CHRAC-17) (Arsenic- transactivated protein) (AsTP).

NFYB_HUMAN
NC score	0.054019 (rank : 11)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	P25208, Q96IY8	Gene names	NFYB, HAP3
Domain Architecture
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

NFYB_MOUSE
NC score	0.050810 (rank : 12)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	P63139, P22569, Q3UK54	Gene names	Nfyb
Domain Architecture	No domain graphic available
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

MRCKB_HUMAN
NC score	0.001766 (rank : 13)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	2239	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).