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Network neighborhood for query Sequence : DPOE3_HUMAN

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DPOE3_HUMAN
SwissProt Accessions	Q9NRF9, Q5W0U1, Q8N758, Q8NCE5, Q9NR32	Gene names	POLE3, CHRAC17
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (Chromatin accessibility complex 17) (HuCHRAC17) (CHRAC-17) (Arsenic- transactivated protein) (AsTP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOE3_MOUSE
θ value	8.30557e-46 (rank : 1)	NC score	0.977565 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JKP7, Q8R198	Gene names	Pole3
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (YB-like protein 1) (YBL1) (NF-YB-like protein).

DPOE3_HUMAN
θ value	1.08474e-45 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NRF9, Q5W0U1, Q8N758, Q8NCE5, Q9NR32	Gene names	POLE3, CHRAC17
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (Chromatin accessibility complex 17) (HuCHRAC17) (CHRAC-17) (Arsenic- transactivated protein) (AsTP).

NFYB_HUMAN
θ value	3.18553e-13 (rank : 3)	NC score	0.721893 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P25208, Q96IY8	Gene names	NFYB, HAP3
Domain Architecture
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

NFYB_MOUSE
θ value	3.18553e-13 (rank : 4)	NC score	0.721882 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P63139, P22569, Q3UK54	Gene names	Nfyb
Domain Architecture	No domain graphic available
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

TBAP_HUMAN
θ value	6.21693e-09 (rank : 5)	NC score	0.675340 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q01658	Gene names	DR1
Domain Architecture
Description	TATA-binding protein-associated phosphoprotein (Down-regulator of transcription 1) (Dr1 protein) (Negative cofactor 2 beta) (NC2 beta).

TBAP_MOUSE
θ value	6.21693e-09 (rank : 6)	NC score	0.673168 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WV0, Q3UT14	Gene names	Dr1
Domain Architecture	No domain graphic available
Description	TATA-binding protein-associated phosphoprotein (Down-regulator of transcription 1) (Negative cofactor 2 beta) (NC2 beta).

CCD16_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.197477 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	190	Shared Neighborhood Hits	15
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

CCD16_MOUSE
θ value	0.0252991 (rank : 8)	NC score	0.196485 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CHRC1_MOUSE
θ value	0.0252991 (rank : 9)	NC score	0.220639 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JKP8, Q91VG2	Gene names	Chrac1
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (YC-like protein 1) (YCL1) (NF-YC-like protein).

MATR3_MOUSE
θ value	0.0431538 (rank : 10)	NC score	0.137557 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

SEC63_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.099679 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	586	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

DPOE4_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.224953 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

DPOE4_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.225717 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQ36, Q3TJ13	Gene names	Pole4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

LEO1_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.080758 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	958	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MATR3_HUMAN
θ value	0.0961366 (rank : 15)	NC score	0.139858 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

CNTRB_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.058087 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	1029	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

SEC63_MOUSE
θ value	0.47712 (rank : 17)	NC score	0.102281 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	601	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

OPTN_MOUSE
θ value	0.62314 (rank : 18)	NC score	0.048991 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	1120	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

LEO1_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.075170 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MAP1A_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.061826 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	1626	Shared Neighborhood Hits	37
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

AKA12_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.064547 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	825	Shared Neighborhood Hits	23
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

P52K_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.047649 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

PRG3_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.034542 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

CMGA_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.061103 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CROCC_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.034769 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	1460	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

ITSN1_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.036113 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	1757	Shared Neighborhood Hits	29
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

NFYC_HUMAN
θ value	1.81305 (rank : 27)	NC score	0.139917 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

NFYC_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.153193 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

CK5P2_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.039057 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	1433	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

ITSN1_MOUSE
θ value	2.36792 (rank : 30)	NC score	0.039401 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	1669	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

MYH6_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.031232 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	1501	Shared Neighborhood Hits	23
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.034191 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	1610	Shared Neighborhood Hits	30
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

F10A1_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.021020 (rank : 59)
Query Neighborhood Hits	54	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

KIF3A_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.027187 (rank : 55)
Query Neighborhood Hits	54	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

KIF3A_MOUSE
θ value	4.03905 (rank : 35)	NC score	0.028295 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	715	Shared Neighborhood Hits	28
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

NALP5_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.023796 (rank : 56)
Query Neighborhood Hits	54	Target Neighborhood Hits	560	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

TCAL5_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.037905 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	806	Shared Neighborhood Hits	25
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZBTB6_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.002185 (rank : 63)
Query Neighborhood Hits	54	Target Neighborhood Hits	805	Shared Neighborhood Hits	5
SwissProt Accessions	Q15916	Gene names	ZBTB6, ZID, ZNF482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain).

MYH7_HUMAN
θ value	5.27518 (rank : 39)	NC score	0.033834 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	1559	Shared Neighborhood Hits	27
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_MOUSE
θ value	5.27518 (rank : 40)	NC score	0.032427 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	1600	Shared Neighborhood Hits	30
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NEK1_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.002564 (rank : 62)
Query Neighborhood Hits	54	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

PEG3_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.006290 (rank : 61)
Query Neighborhood Hits	54	Target Neighborhood Hits	1101	Shared Neighborhood Hits	13
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PEPL_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.030875 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	1141	Shared Neighborhood Hits	27
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

SMC1A_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.041805 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	1346	Shared Neighborhood Hits	29
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.042378 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	1384	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

ANR12_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.023699 (rank : 57)
Query Neighborhood Hits	54	Target Neighborhood Hits	1081	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

IWS1_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.035367 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	1258	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RAD50_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.034971 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	1317	Shared Neighborhood Hits	29
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TXLNB_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.032672 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	912	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

MYH6_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.030149 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	1426	Shared Neighborhood Hits	24
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

OPTN_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.050862 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	827	Shared Neighborhood Hits	26
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

PPIG_HUMAN
θ value	8.99809 (rank : 52)	NC score	0.027981 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	670	Shared Neighborhood Hits	26
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

RPTN_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.020978 (rank : 60)
Query Neighborhood Hits	54	Target Neighborhood Hits	406	Shared Neighborhood Hits	12
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

S6OS1_HUMAN
θ value	8.99809 (rank : 54)	NC score	0.022196 (rank : 58)
Query Neighborhood Hits	54	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1H7	Gene names	SIX6OS1, C14orf39
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

CHRC1_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.106537 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

NSBP1_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.069219 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

NUCKS_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.057250 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	143	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

PTMA_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.093326 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.086413 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.101128 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	111	Shared Neighborhood Hits	23
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.087995 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

RBM25_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.052503 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	682	Shared Neighborhood Hits	34
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RPGR1_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.061859 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	713	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

Hits sorted by NC score

DPOE3_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.08474e-45 (rank : 2)
Query Neighborhood Hits	54	Target Neighborhood Hits	54	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NRF9, Q5W0U1, Q8N758, Q8NCE5, Q9NR32	Gene names	POLE3, CHRAC17
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (Chromatin accessibility complex 17) (HuCHRAC17) (CHRAC-17) (Arsenic- transactivated protein) (AsTP).

DPOE3_MOUSE
NC score	0.977565 (rank : 2)	θ value	8.30557e-46 (rank : 1)
Query Neighborhood Hits	54	Target Neighborhood Hits	51	Shared Neighborhood Hits	36
SwissProt Accessions	Q9JKP7, Q8R198	Gene names	Pole3
Domain Architecture
Description	DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) (YB-like protein 1) (YBL1) (NF-YB-like protein).

NFYB_HUMAN
NC score	0.721893 (rank : 3)	θ value	3.18553e-13 (rank : 3)
Query Neighborhood Hits	54	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P25208, Q96IY8	Gene names	NFYB, HAP3
Domain Architecture
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

NFYB_MOUSE
NC score	0.721882 (rank : 4)	θ value	3.18553e-13 (rank : 4)
Query Neighborhood Hits	54	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P63139, P22569, Q3UK54	Gene names	Nfyb
Domain Architecture	No domain graphic available
Description	Nuclear transcription factor Y subunit beta (Nuclear transcription factor Y subunit B) (NF-YB) (CAAT-box DNA-binding protein subunit B).

TBAP_HUMAN
NC score	0.675340 (rank : 5)	θ value	6.21693e-09 (rank : 5)
Query Neighborhood Hits	54	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q01658	Gene names	DR1
Domain Architecture
Description	TATA-binding protein-associated phosphoprotein (Down-regulator of transcription 1) (Dr1 protein) (Negative cofactor 2 beta) (NC2 beta).

TBAP_MOUSE
NC score	0.673168 (rank : 6)	θ value	6.21693e-09 (rank : 6)
Query Neighborhood Hits	54	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q91WV0, Q3UT14	Gene names	Dr1
Domain Architecture	No domain graphic available
Description	TATA-binding protein-associated phosphoprotein (Down-regulator of transcription 1) (Negative cofactor 2 beta) (NC2 beta).

DPOE4_MOUSE
NC score	0.225717 (rank : 7)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	54	Target Neighborhood Hits	13	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CQ36, Q3TJ13	Gene names	Pole4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

DPOE4_HUMAN
NC score	0.224953 (rank : 8)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	54	Target Neighborhood Hits	11	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NR33, Q53TR2	Gene names	POLE4
Domain Architecture
Description	DNA polymerase epsilon subunit 4 (EC 2.7.7.7) (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12).

CHRC1_MOUSE
NC score	0.220639 (rank : 9)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	54	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JKP8, Q91VG2	Gene names	Chrac1
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (DNA polymerase epsilon subunit p15) (YC-like protein 1) (YCL1) (NF-YC-like protein).

CCD16_HUMAN
NC score	0.197477 (rank : 10)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	54	Target Neighborhood Hits	190	Shared Neighborhood Hits	15
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

CCD16_MOUSE
NC score	0.196485 (rank : 11)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	54	Target Neighborhood Hits	218	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

NFYC_MOUSE
NC score	0.153193 (rank : 12)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	54	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

NFYC_HUMAN
NC score	0.139917 (rank : 13)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	54	Target Neighborhood Hits	46	Shared Neighborhood Hits	10
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

MATR3_HUMAN
NC score	0.139858 (rank : 14)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	54	Target Neighborhood Hits	325	Shared Neighborhood Hits	12
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MATR3_MOUSE
NC score	0.137557 (rank : 15)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	54	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

CHRC1_HUMAN
NC score	0.106537 (rank : 16)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	54	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRG0	Gene names	CHRAC1, CHRAC15
Domain Architecture
Description	Chromatin accessibility complex protein 1 (CHRAC-1) (CHRAC-15) (HuCHRAC15) (DNA polymerase epsilon subunit p15).

SEC63_MOUSE
NC score	0.102281 (rank : 17)	θ value	0.47712 (rank : 17)
Query Neighborhood Hits	54	Target Neighborhood Hits	601	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

PTMS_HUMAN
NC score	0.101128 (rank : 18)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	54	Target Neighborhood Hits	111	Shared Neighborhood Hits	23
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

SEC63_HUMAN
NC score	0.099679 (rank : 19)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	54	Target Neighborhood Hits	586	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

PTMA_HUMAN
NC score	0.093326 (rank : 20)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	54	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMS_MOUSE
NC score	0.087995 (rank : 21)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	54	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMA_MOUSE
NC score	0.086413 (rank : 22)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	54	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

LEO1_HUMAN
NC score	0.080758 (rank : 23)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	54	Target Neighborhood Hits	958	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
NC score	0.075170 (rank : 24)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	54	Target Neighborhood Hits	946	Shared Neighborhood Hits	23
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

NSBP1_HUMAN
NC score	0.069219 (rank : 25)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	54	Target Neighborhood Hits	251	Shared Neighborhood Hits	23
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

AKA12_HUMAN
NC score	0.064547 (rank : 26)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	54	Target Neighborhood Hits	825	Shared Neighborhood Hits	23
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

RPGR1_MOUSE
NC score	0.061859 (rank : 27)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	54	Target Neighborhood Hits	713	Shared Neighborhood Hits	40
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

MAP1A_HUMAN
NC score	0.061826 (rank : 28)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	54	Target Neighborhood Hits	1626	Shared Neighborhood Hits	37
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

CMGA_HUMAN
NC score	0.061103 (rank : 29)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	54	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CNTRB_MOUSE
NC score	0.058087 (rank : 30)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	54	Target Neighborhood Hits	1029	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NUCKS_HUMAN
NC score	0.057250 (rank : 31)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	54	Target Neighborhood Hits	143	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H1E3, Q9H1D6, Q9H723	Gene names	NUCKS1, NUCKS
Domain Architecture	No domain graphic available
Description	Nuclear ubiquitous casein and cyclin-dependent kinases substrate (P1).

RBM25_HUMAN
NC score	0.052503 (rank : 32)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	54	Target Neighborhood Hits	682	Shared Neighborhood Hits	34
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

OPTN_HUMAN
NC score	0.050862 (rank : 33)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	54	Target Neighborhood Hits	827	Shared Neighborhood Hits	26
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
NC score	0.048991 (rank : 34)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	54	Target Neighborhood Hits	1120	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

P52K_HUMAN
NC score	0.047649 (rank : 35)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	54	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

SMC1A_MOUSE
NC score	0.042378 (rank : 36)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	54	Target Neighborhood Hits	1384	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SMC1A_HUMAN
NC score	0.041805 (rank : 37)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	54	Target Neighborhood Hits	1346	Shared Neighborhood Hits	29
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

ITSN1_MOUSE
NC score	0.039401 (rank : 38)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	54	Target Neighborhood Hits	1669	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

CK5P2_HUMAN
NC score	0.039057 (rank : 39)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	54	Target Neighborhood Hits	1433	Shared Neighborhood Hits	31
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

TCAL5_HUMAN
NC score	0.037905 (rank : 40)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	54	Target Neighborhood Hits	806	Shared Neighborhood Hits	25
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ITSN1_HUMAN
NC score	0.036113 (rank : 41)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	54	Target Neighborhood Hits	1757	Shared Neighborhood Hits	29
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

IWS1_MOUSE
NC score	0.035367 (rank : 42)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	54	Target Neighborhood Hits	1258	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RAD50_HUMAN
NC score	0.034971 (rank : 43)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	54	Target Neighborhood Hits	1317	Shared Neighborhood Hits	29
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CROCC_MOUSE
NC score	0.034769 (rank : 44)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	54	Target Neighborhood Hits	1460	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

PRG3_MOUSE
NC score	0.034542 (rank : 45)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	54	Target Neighborhood Hits	103	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JL95, Q3SXA9	Gene names	Prg3, Mbp2
Domain Architecture	No domain graphic available
Description	Proteoglycan 3 precursor (Eosinophil major basic protein 2).

MYH8_HUMAN
NC score	0.034191 (rank : 46)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	54	Target Neighborhood Hits	1610	Shared Neighborhood Hits	30
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH7_HUMAN
NC score	0.033834 (rank : 47)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	54	Target Neighborhood Hits	1559	Shared Neighborhood Hits	27
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

TXLNB_HUMAN
NC score	0.032672 (rank : 48)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	54	Target Neighborhood Hits	912	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

MYH8_MOUSE
NC score	0.032427 (rank : 49)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	54	Target Neighborhood Hits	1600	Shared Neighborhood Hits	30
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH6_MOUSE
NC score	0.031232 (rank : 50)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	54	Target Neighborhood Hits	1501	Shared Neighborhood Hits	23
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PEPL_HUMAN
NC score	0.030875 (rank : 51)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	54	Target Neighborhood Hits	1141	Shared Neighborhood Hits	27
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

MYH6_HUMAN
NC score	0.030149 (rank : 52)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	54	Target Neighborhood Hits	1426	Shared Neighborhood Hits	24
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

KIF3A_MOUSE
NC score	0.028295 (rank : 53)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	54	Target Neighborhood Hits	715	Shared Neighborhood Hits	28
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

PPIG_HUMAN
NC score	0.027981 (rank : 54)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	54	Target Neighborhood Hits	670	Shared Neighborhood Hits	26
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

KIF3A_HUMAN
NC score	0.027187 (rank : 55)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	54	Target Neighborhood Hits	704	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

NALP5_MOUSE
NC score	0.023796 (rank : 56)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	54	Target Neighborhood Hits	560	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

ANR12_HUMAN
NC score	0.023699 (rank : 57)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	54	Target Neighborhood Hits	1081	Shared Neighborhood Hits	27
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

S6OS1_HUMAN
NC score	0.022196 (rank : 58)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	54	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N1H7	Gene names	SIX6OS1, C14orf39
Domain Architecture	No domain graphic available
Description	Protein SIX6OS1 (Six6 opposite strand transcript 1).

F10A1_HUMAN
NC score	0.021020 (rank : 59)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	54	Target Neighborhood Hits	312	Shared Neighborhood Hits	6
SwissProt Accessions	P50502, O14999	Gene names	ST13, FAM10A1, HIP, SNC6
Domain Architecture
Description	Hsc70-interacting protein (Hip) (Suppression of tumorigenicity protein 13) (Putative tumor suppressor ST13) (Protein FAM10A1) (Progesterone receptor-associated p48 protein) (NY-REN-33 antigen).

RPTN_HUMAN
NC score	0.020978 (rank : 60)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	54	Target Neighborhood Hits	406	Shared Neighborhood Hits	12
SwissProt Accessions	Q6XPR3	Gene names	RPTN
Domain Architecture	No domain graphic available
Description	Repetin.

PEG3_MOUSE
NC score	0.006290 (rank : 61)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	54	Target Neighborhood Hits	1101	Shared Neighborhood Hits	13
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

NEK1_MOUSE
NC score	0.002564 (rank : 62)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	54	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	P51954	Gene names	Nek1
Domain Architecture
Description	Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (NimA-related protein kinase 1).

ZBTB6_HUMAN
NC score	0.002185 (rank : 63)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	54	Target Neighborhood Hits	805	Shared Neighborhood Hits	5
SwissProt Accessions	Q15916	Gene names	ZBTB6, ZID, ZNF482
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 6 (Zinc finger protein 482) (Zinc finger protein with interaction domain).