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Network neighborhood for query Sequence : H2A2A_HUMAN

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H2A2A_HUMAN
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

H2A2A_HUMAN
θ value	2.57589e-55 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).

H2A2A_MOUSE
θ value	2.57589e-55 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q6GSS7, P20670, Q811M3	Gene names	Hist2h2aa1
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2) (H2a-614) (H2a-615).

H2A1_HUMAN
θ value	5.73848e-55 (rank : 3)	NC score	0.999952 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P0C0S8, P02261, Q2M1R2, Q76PA6	Gene names	HIST1H2AG, H2AFP
Domain Architecture	No domain graphic available
Description	Histone H2A type 1 (H2A.1).

H2A1C_HUMAN
θ value	1.2784e-54 (rank : 4)	NC score	0.999945 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q93077, O00775, O00776, O00777, O00778, Q540R1	Gene names	HIST1H2AC, H2AFL
Domain Architecture
Description	Histone H2A type 1-C.

H2A1D_HUMAN
θ value	1.2784e-54 (rank : 5)	NC score	0.999888 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P20671, P57754, Q6FGY6	Gene names	HIST1H2AD, H2AFG
Domain Architecture
Description	Histone H2A type 1-D (H2A.3).

H2A1E_HUMAN
θ value	2.84797e-54 (rank : 6)	NC score	0.999871 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P28001, Q76P63	Gene names	HIST1H2AE, H2AFA
Domain Architecture
Description	Histone H2A type 1-E (H2A.2) (H2A/m).

H2A1_MOUSE
θ value	2.84797e-54 (rank : 7)	NC score	0.999871 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P22752, P10812, Q5SZZ2	Gene names	Hist1h2ab
Domain Architecture
Description	Histone H2A type 1.

H2A3_HUMAN
θ value	2.84797e-54 (rank : 8)	NC score	0.999868 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q7L7L0	Gene names	HIST3H2A
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A3_MOUSE
θ value	2.84797e-54 (rank : 9)	NC score	0.999868 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BFU2	Gene names	Hist3h2a
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A1K_MOUSE
θ value	6.34462e-54 (rank : 10)	NC score	0.999870 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGP7	Gene names	Hist1h2ak
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-K.

H2A1F_MOUSE
θ value	1.08223e-53 (rank : 11)	NC score	0.999865 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGP5	Gene names	Hist1h2af
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-F.

H2A1H_HUMAN
θ value	1.08223e-53 (rank : 12)	NC score	0.999947 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KK5	Gene names	HIST1H2AH, HIST1H2AI
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1J_HUMAN
θ value	3.1488e-53 (rank : 13)	NC score	0.999940 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q99878, Q5JXQ5	Gene names	HIST1H2AJ, H2AFE
Domain Architecture
Description	Histone H2A type 1-J.

H2A1B_HUMAN
θ value	5.37103e-53 (rank : 14)	NC score	0.999785 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	38
SwissProt Accessions	P04908	Gene names	HIST1H2AB, H2AFM
Domain Architecture
Description	Histone H2A type 1-B.

H2A1H_MOUSE
θ value	5.37103e-53 (rank : 15)	NC score	0.999872 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGP6	Gene names	Hist1h2ah
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A2C_HUMAN
θ value	2.66562e-52 (rank : 16)	NC score	0.999876 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q16777, Q6DRA7, Q8IUE5	Gene names	HIST2H2AC, H2AFQ
Domain Architecture
Description	Histone H2A type 2-C (H2A-GL101) (H2A/r).

H2A2C_MOUSE
θ value	2.66562e-52 (rank : 17)	NC score	0.999876 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q64523, Q8CGP3	Gene names	Hist2h2ac, Hist2h2ab
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-C (H2a-613B).

H2A2B_MOUSE
θ value	1.72781e-51 (rank : 18)	NC score	0.999770 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q64522	Gene names
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B (H2a-613A).

H2A2B_HUMAN
θ value	3.84914e-51 (rank : 19)	NC score	0.999782 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUE6	Gene names	HIST2H2AB
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B.

H2A1A_HUMAN
θ value	5.02714e-51 (rank : 20)	NC score	0.999718 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q96QV6	Gene names	HIST1H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-A.

H2AX_HUMAN
θ value	6.7944e-48 (rank : 21)	NC score	0.998935 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P16104, Q4ZGJ7, Q6IAS5	Gene names	H2AFX, H2AX
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AX_MOUSE
θ value	1.97686e-47 (rank : 22)	NC score	0.998877 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P27661	Gene names	H2afx, H2a.x, H2ax, Hist5-2ax
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AW_HUMAN
θ value	2.96089e-35 (rank : 23)	NC score	0.941540 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_MOUSE
θ value	2.96089e-35 (rank : 24)	NC score	0.942021 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_HUMAN
θ value	1.37539e-32 (rank : 25)	NC score	0.925835 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

H2AY_MOUSE
θ value	1.37539e-32 (rank : 26)	NC score	0.926004 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AZ_HUMAN
θ value	1.2049e-28 (rank : 27)	NC score	0.977995 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	P0C0S5, P17317, Q6I9U0	Gene names	H2AFZ, H2AZ
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AZ_MOUSE
θ value	1.2049e-28 (rank : 28)	NC score	0.977995 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	P0C0S6, P17317, Q3UA55, Q3UK43, Q68FD2	Gene names	H2afz, H2az
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AV_HUMAN
θ value	1.57365e-28 (rank : 29)	NC score	0.977827 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q71UI9, Q59GV8, Q6PK98	Gene names	H2AFV, H2AV
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AV_MOUSE
θ value	1.57365e-28 (rank : 30)	NC score	0.977827 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q3THW5, Q5NC92, Q6ZWU0	Gene names	H2afv, H2av
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AFB_HUMAN
θ value	4.74913e-17 (rank : 31)	NC score	0.978098 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P98176, Q5TZB2, Q6FG78, Q96PR7	Gene names	H2AFB3, H2ABBD, H2AFB
Domain Architecture
Description	Histone H2A-Bbd (H2A Barr body-deficient) (H2A.Bbd).

SOS1_MOUSE
θ value	1.43324e-05 (rank : 32)	NC score	0.332016 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	281	Shared Neighborhood Hits	34
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS1_HUMAN
θ value	4.1701e-05 (rank : 33)	NC score	0.320543 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	274	Shared Neighborhood Hits	34
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS2_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.267484 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	193	Shared Neighborhood Hits	34
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

DRAP1_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.225484 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DRAP1_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.219854 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

ABTB2_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.066687 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	414	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ABTB2_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.061336 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	391	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

NFYC_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.051338 (rank : 47)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).

NFYC_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.057970 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	17
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

LRP16_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.052298 (rank : 46)
Query Neighborhood Hits	40	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

LRP16_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.052887 (rank : 45)
Query Neighborhood Hits	40	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

PAR14_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.061209 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR14_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.064600 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

PAR15_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.060898 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

PARP9_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.056368 (rank : 44)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

PARP9_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.067448 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

Hits sorted by NC score

H2A2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.57589e-55 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q6FI13, P20670	Gene names	HIST2H2AA3, H2AFO, HIST2H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2).

H2A2A_MOUSE
NC score	0.999962 (rank : 2)	θ value	2.57589e-55 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q6GSS7, P20670, Q811M3	Gene names	Hist2h2aa1
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-A (H2A.2) (H2a-614) (H2a-615).

H2A1_HUMAN
NC score	0.999952 (rank : 3)	θ value	5.73848e-55 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P0C0S8, P02261, Q2M1R2, Q76PA6	Gene names	HIST1H2AG, H2AFP
Domain Architecture	No domain graphic available
Description	Histone H2A type 1 (H2A.1).

H2A1H_HUMAN
NC score	0.999947 (rank : 4)	θ value	1.08223e-53 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q96KK5	Gene names	HIST1H2AH, HIST1H2AI
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1C_HUMAN
NC score	0.999945 (rank : 5)	θ value	1.2784e-54 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q93077, O00775, O00776, O00777, O00778, Q540R1	Gene names	HIST1H2AC, H2AFL
Domain Architecture
Description	Histone H2A type 1-C.

H2A1J_HUMAN
NC score	0.999940 (rank : 6)	θ value	3.1488e-53 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q99878, Q5JXQ5	Gene names	HIST1H2AJ, H2AFE
Domain Architecture
Description	Histone H2A type 1-J.

H2A1D_HUMAN
NC score	0.999888 (rank : 7)	θ value	1.2784e-54 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P20671, P57754, Q6FGY6	Gene names	HIST1H2AD, H2AFG
Domain Architecture
Description	Histone H2A type 1-D (H2A.3).

H2A2C_HUMAN
NC score	0.999876 (rank : 8)	θ value	2.66562e-52 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q16777, Q6DRA7, Q8IUE5	Gene names	HIST2H2AC, H2AFQ
Domain Architecture
Description	Histone H2A type 2-C (H2A-GL101) (H2A/r).

H2A2C_MOUSE
NC score	0.999876 (rank : 9)	θ value	2.66562e-52 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q64523, Q8CGP3	Gene names	Hist2h2ac, Hist2h2ab
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-C (H2a-613B).

H2A1H_MOUSE
NC score	0.999872 (rank : 10)	θ value	5.37103e-53 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGP6	Gene names	Hist1h2ah
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-H.

H2A1E_HUMAN
NC score	0.999871 (rank : 11)	θ value	2.84797e-54 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P28001, Q76P63	Gene names	HIST1H2AE, H2AFA
Domain Architecture
Description	Histone H2A type 1-E (H2A.2) (H2A/m).

H2A1_MOUSE
NC score	0.999871 (rank : 12)	θ value	2.84797e-54 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	P22752, P10812, Q5SZZ2	Gene names	Hist1h2ab
Domain Architecture
Description	Histone H2A type 1.

H2A1K_MOUSE
NC score	0.999870 (rank : 13)	θ value	6.34462e-54 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGP7	Gene names	Hist1h2ak
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-K.

H2A3_HUMAN
NC score	0.999868 (rank : 14)	θ value	2.84797e-54 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q7L7L0	Gene names	HIST3H2A
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A3_MOUSE
NC score	0.999868 (rank : 15)	θ value	2.84797e-54 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BFU2	Gene names	Hist3h2a
Domain Architecture	No domain graphic available
Description	Histone H2A type 3.

H2A1F_MOUSE
NC score	0.999865 (rank : 16)	θ value	1.08223e-53 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	38	Shared Neighborhood Hits	38
SwissProt Accessions	Q8CGP5	Gene names	Hist1h2af
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-F.

H2A1B_HUMAN
NC score	0.999785 (rank : 17)	θ value	5.37103e-53 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	38
SwissProt Accessions	P04908	Gene names	HIST1H2AB, H2AFM
Domain Architecture
Description	Histone H2A type 1-B.

H2A2B_HUMAN
NC score	0.999782 (rank : 18)	θ value	3.84914e-51 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q8IUE6	Gene names	HIST2H2AB
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B.

H2A2B_MOUSE
NC score	0.999770 (rank : 19)	θ value	1.72781e-51 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q64522	Gene names
Domain Architecture	No domain graphic available
Description	Histone H2A type 2-B (H2a-613A).

H2A1A_HUMAN
NC score	0.999718 (rank : 20)	θ value	5.02714e-51 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q96QV6	Gene names	HIST1H2AA
Domain Architecture	No domain graphic available
Description	Histone H2A type 1-A.

H2AX_HUMAN
NC score	0.998935 (rank : 21)	θ value	6.7944e-48 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P16104, Q4ZGJ7, Q6IAS5	Gene names	H2AFX, H2AX
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AX_MOUSE
NC score	0.998877 (rank : 22)	θ value	1.97686e-47 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	P27661	Gene names	H2afx, H2a.x, H2ax, Hist5-2ax
Domain Architecture
Description	Histone H2A.x (H2a/x).

H2AFB_HUMAN
NC score	0.978098 (rank : 23)	θ value	4.74913e-17 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P98176, Q5TZB2, Q6FG78, Q96PR7	Gene names	H2AFB3, H2ABBD, H2AFB
Domain Architecture
Description	Histone H2A-Bbd (H2A Barr body-deficient) (H2A.Bbd).

H2AZ_HUMAN
NC score	0.977995 (rank : 24)	θ value	1.2049e-28 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	P0C0S5, P17317, Q6I9U0	Gene names	H2AFZ, H2AZ
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AZ_MOUSE
NC score	0.977995 (rank : 25)	θ value	1.2049e-28 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	P0C0S6, P17317, Q3UA55, Q3UK43, Q68FD2	Gene names	H2afz, H2az
Domain Architecture	No domain graphic available
Description	Histone H2A.Z (H2A/z).

H2AV_HUMAN
NC score	0.977827 (rank : 26)	θ value	1.57365e-28 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q71UI9, Q59GV8, Q6PK98	Gene names	H2AFV, H2AV
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AV_MOUSE
NC score	0.977827 (rank : 27)	θ value	1.57365e-28 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	34	Shared Neighborhood Hits	34
SwissProt Accessions	Q3THW5, Q5NC92, Q6ZWU0	Gene names	H2afv, H2av
Domain Architecture	No domain graphic available
Description	Histone H2AV (H2A.F/Z).

H2AW_MOUSE
NC score	0.942021 (rank : 28)	θ value	2.96089e-35 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	57	Shared Neighborhood Hits	36
SwissProt Accessions	Q8CCK0, Q3TNT4, Q925I6	Gene names	H2afy2, H2afy3
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AW_HUMAN
NC score	0.941540 (rank : 29)	θ value	2.96089e-35 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	56	Shared Neighborhood Hits	36
SwissProt Accessions	Q9P0M6, Q5SQT2	Gene names	H2AFY2, MACROH2A2
Domain Architecture
Description	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2).

H2AY_MOUSE
NC score	0.926004 (rank : 30)	θ value	1.37539e-32 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	49	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZQ8, Q91VZ2, Q9QZQ7	Gene names	H2afy
Domain Architecture	No domain graphic available
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y).

H2AY_HUMAN
NC score	0.925835 (rank : 31)	θ value	1.37539e-32 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	34
SwissProt Accessions	O75367, O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96	Gene names	H2AFY, MACROH2A1
Domain Architecture
Description	Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y) (Medulloblastoma antigen MU-MB-50.205).

SOS1_MOUSE
NC score	0.332016 (rank : 32)	θ value	1.43324e-05 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	281	Shared Neighborhood Hits	34
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

SOS1_HUMAN
NC score	0.320543 (rank : 33)	θ value	4.1701e-05 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	274	Shared Neighborhood Hits	34
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

SOS2_HUMAN
NC score	0.267484 (rank : 34)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	193	Shared Neighborhood Hits	34
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

DRAP1_HUMAN
NC score	0.225484 (rank : 35)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	Q14919, Q13448	Gene names	DRAP1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

DRAP1_MOUSE
NC score	0.219854 (rank : 36)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D6N5	Gene names	Drap1
Domain Architecture	No domain graphic available
Description	Dr1-associated corepressor (Dr1-associated protein 1) (Negative co- factor 2 alpha) (NC2 alpha).

PARP9_MOUSE
NC score	0.067448 (rank : 37)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CAS9, Q99LF9	Gene names	Parp9, Bal
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein homolog).

ABTB2_MOUSE
NC score	0.066687 (rank : 38)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	414	Shared Neighborhood Hits	27
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

PAR14_MOUSE
NC score	0.064600 (rank : 39)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	40	Target Neighborhood Hits	113	Shared Neighborhood Hits	4
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

ABTB2_HUMAN
NC score	0.061336 (rank : 40)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	391	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

PAR14_HUMAN
NC score	0.061209 (rank : 41)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	40	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	Q460N5, Q460N4, Q8J027, Q9H9X9, Q9NV60, Q9ULF2	Gene names	PARP14, BAL2, KIAA1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (B aggressive lymphoma protein 2).

PAR15_HUMAN
NC score	0.060898 (rank : 42)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	40	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q460N3, Q8N1K3	Gene names	PARP15, BAL3
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 15 (EC 2.4.2.30) (PARP-15) (B-aggressive lymphoma protein 3).

NFYC_MOUSE
NC score	0.057970 (rank : 43)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	17
SwissProt Accessions	P70353, O35088, Q6GU21	Gene names	Nfyc
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C).

PARP9_HUMAN
NC score	0.056368 (rank : 44)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IXQ6, Q8TCP3, Q9BZL8, Q9BZL9	Gene names	PARP9, BAL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 9 (EC 2.4.2.30) (PARP-9) (B aggressive lymphoma protein).

LRP16_MOUSE
NC score	0.052887 (rank : 45)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	40	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q922B1	Gene names	Lrp16
Domain Architecture
Description	Protein LRP16.

LRP16_HUMAN
NC score	0.052298 (rank : 46)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BQ69, Q9UH96	Gene names	LRP16
Domain Architecture
Description	Protein LRP16.

NFYC_HUMAN
NC score	0.051338 (rank : 47)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q13952, Q5T6K8, Q5T6L1, Q5TZR6, Q92869, Q9HBX1, Q9NXB5, Q9UM67, Q9UML0, Q9UMT7	Gene names	NFYC
Domain Architecture
Description	Nuclear transcription factor Y subunit gamma (Nuclear transcription factor Y subunit C) (NF-YC) (CAAT-box DNA-binding protein subunit C) (Transactivator HSM-1/2).