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Network neighborhood for query Sequence : TCFL5_HUMAN

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TCFL5_HUMAN
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TCFL5_HUMAN
θ value	3.96267e-181 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

BMAL1_HUMAN
θ value	0.0113563 (rank : 2)	NC score	0.205864 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	0.0113563 (rank : 3)	NC score	0.205259 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

MAD1_MOUSE
θ value	0.0113563 (rank : 4)	NC score	0.230905 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MLX_MOUSE
θ value	0.0563607 (rank : 5)	NC score	0.204771 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MXI1_HUMAN
θ value	0.0736092 (rank : 6)	NC score	0.225610 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
θ value	0.0736092 (rank : 7)	NC score	0.223373 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	19
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MNT_MOUSE
θ value	0.0961366 (rank : 8)	NC score	0.186407 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	432	Shared Neighborhood Hits	23
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MAD1_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.216170 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	68	Shared Neighborhood Hits	21
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

TFEB_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.195340 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.125558 (rank : 11)	NC score	0.196580 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	119	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MLX_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.191355 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

ARNT_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.193817 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.190103 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MNT_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.174868 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	496	Shared Neighborhood Hits	23
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

USF2_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.232648 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF1_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.232757 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	0.279714 (rank : 18)	NC score	0.232540 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

ARNT2_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.183829 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	0.47712 (rank : 20)	NC score	0.184628 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

USF2_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.220047 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

K0310_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.065014 (rank : 57)
Query Neighborhood Hits	43	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

MAD4_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.195729 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAP1B_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.033651 (rank : 80)
Query Neighborhood Hits	43	Target Neighborhood Hits	977	Shared Neighborhood Hits	10
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

CLOCK_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.132758 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.130633 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

NALDL_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.022089 (rank : 87)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQQ1, O43176	Gene names	NAALADL1, NAALADASEL, NAALADL
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).

PHAR1_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.038505 (rank : 79)
Query Neighborhood Hits	43	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

HAIR_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.022914 (rank : 85)
Query Neighborhood Hits	43	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

NPAS2_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.129367 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.127927 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

TTC16_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.022821 (rank : 86)
Query Neighborhood Hits	43	Target Neighborhood Hits	417	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

DCP1A_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.027546 (rank : 82)
Query Neighborhood Hits	43	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

MAP1A_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.020804 (rank : 88)
Query Neighborhood Hits	43	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PDXL2_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.025818 (rank : 83)
Query Neighborhood Hits	43	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PLRG1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.007951 (rank : 89)
Query Neighborhood Hits	43	Target Neighborhood Hits	318	Shared Neighborhood Hits	2
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.

WBS14_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.068592 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	273	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

IER5_MOUSE
θ value	8.99809 (rank : 38)	NC score	0.023890 (rank : 84)
Query Neighborhood Hits	43	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

MAX_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.145998 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MITF_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.158218 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.155810 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

PHAR1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.032707 (rank : 81)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

TFE3_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.160439 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	190	Shared Neighborhood Hits	31
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

AHR_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.068199 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.065126 (rank : 56)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

BHLH3_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.056871 (rank : 70)
Query Neighborhood Hits	43	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.054346 (rank : 77)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

EPAS1_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.078977 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.078190 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HEY1_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.065846 (rank : 53)
Query Neighborhood Hits	43	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.068125 (rank : 49)
Query Neighborhood Hits	43	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.070499 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.068575 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HIF1A_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.075848 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.075700 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

MAD3_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.153789 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.152605 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD4_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.152343 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAX_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.134367 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MYCL1_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.065700 (rank : 54)
Query Neighborhood Hits	43	Target Neighborhood Hits	146	Shared Neighborhood Hits	29
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.070082 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCN_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.062617 (rank : 59)
Query Neighborhood Hits	43	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCN_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.062015 (rank : 61)
Query Neighborhood Hits	43	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

MYCS_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.054725 (rank : 76)
Query Neighborhood Hits	43	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

MYC_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.067639 (rank : 51)
Query Neighborhood Hits	43	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

MYC_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.070245 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

NCOA1_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.062012 (rank : 62)
Query Neighborhood Hits	43	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.062117 (rank : 60)
Query Neighborhood Hits	43	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA3_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.059109 (rank : 67)
Query Neighborhood Hits	43	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.051627 (rank : 78)
Query Neighborhood Hits	43	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NPAS1_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.060381 (rank : 65)
Query Neighborhood Hits	43	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS1_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.060532 (rank : 64)
Query Neighborhood Hits	43	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS3_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.063824 (rank : 58)
Query Neighborhood Hits	43	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.065597 (rank : 55)
Query Neighborhood Hits	43	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

PER1_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.055475 (rank : 73)
Query Neighborhood Hits	43	Target Neighborhood Hits	215	Shared Neighborhood Hits	12
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.056786 (rank : 71)
Query Neighborhood Hits	43	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.059229 (rank : 66)
Query Neighborhood Hits	43	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.058812 (rank : 69)
Query Neighborhood Hits	43	Target Neighborhood Hits	325	Shared Neighborhood Hits	15
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER3_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.055197 (rank : 74)
Query Neighborhood Hits	43	Target Neighborhood Hits	479	Shared Neighborhood Hits	11
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER3_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.059061 (rank : 68)
Query Neighborhood Hits	43	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

SIM1_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.069678 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.069764 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.070143 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.068799 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

SRBP1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.067982 (rank : 50)
Query Neighborhood Hits	43	Target Neighborhood Hits	225	Shared Neighborhood Hits	25
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.067114 (rank : 52)
Query Neighborhood Hits	43	Target Neighborhood Hits	384	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.060946 (rank : 63)
Query Neighborhood Hits	43	Target Neighborhood Hits	133	Shared Neighborhood Hits	26
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

TFAP4_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.054856 (rank : 75)
Query Neighborhood Hits	43	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

WBS14_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.056333 (rank : 72)
Query Neighborhood Hits	43	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

Hits sorted by NC score

TCFL5_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.96267e-181 (rank : 1)
Query Neighborhood Hits	43	Target Neighborhood Hits	43	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

USF1_HUMAN
NC score	0.232757 (rank : 2)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	28
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.232648 (rank : 3)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	43	Target Neighborhood Hits	155	Shared Neighborhood Hits	29
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF1_MOUSE
NC score	0.232540 (rank : 4)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	43	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

MAD1_MOUSE
NC score	0.230905 (rank : 5)	θ value	0.0113563 (rank : 4)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	P50538, Q60798, Q61825	Gene names	Mxd1, Mad, Mad1
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

MXI1_HUMAN
NC score	0.225610 (rank : 6)	θ value	0.0736092 (rank : 6)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	19
SwissProt Accessions	P50539, Q15887	Gene names	MXI1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

MXI1_MOUSE
NC score	0.223373 (rank : 7)	θ value	0.0736092 (rank : 7)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	19
SwissProt Accessions	P50540	Gene names	Mxi1
Domain Architecture
Description	MAX-interacting protein 1 (Protein MXI1).

USF2_MOUSE
NC score	0.220047 (rank : 8)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	43	Target Neighborhood Hits	173	Shared Neighborhood Hits	29
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

MAD1_HUMAN
NC score	0.216170 (rank : 9)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	43	Target Neighborhood Hits	68	Shared Neighborhood Hits	21
SwissProt Accessions	Q05195	Gene names	MXD1, MAD
Domain Architecture
Description	MAD protein (MAX dimerizer) (MAX dimerization protein 1).

BMAL1_HUMAN
NC score	0.205864 (rank : 10)	θ value	0.0113563 (rank : 2)
Query Neighborhood Hits	43	Target Neighborhood Hits	115	Shared Neighborhood Hits	28
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.205259 (rank : 11)	θ value	0.0113563 (rank : 3)
Query Neighborhood Hits	43	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

MLX_MOUSE
NC score	0.204771 (rank : 12)	θ value	0.0563607 (rank : 5)
Query Neighborhood Hits	43	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TFEB_MOUSE
NC score	0.196580 (rank : 13)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	43	Target Neighborhood Hits	119	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

MAD4_HUMAN
NC score	0.195729 (rank : 14)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	43	Target Neighborhood Hits	94	Shared Neighborhood Hits	23
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

TFEB_HUMAN
NC score	0.195340 (rank : 15)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	43	Target Neighborhood Hits	111	Shared Neighborhood Hits	28
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

ARNT_HUMAN
NC score	0.193817 (rank : 16)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	28
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MLX_HUMAN
NC score	0.191355 (rank : 17)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	43	Target Neighborhood Hits	95	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

ARNT_MOUSE
NC score	0.190103 (rank : 18)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	43	Target Neighborhood Hits	213	Shared Neighborhood Hits	27
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

MNT_MOUSE
NC score	0.186407 (rank : 19)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	43	Target Neighborhood Hits	432	Shared Neighborhood Hits	23
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

ARNT2_MOUSE
NC score	0.184628 (rank : 20)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	43	Target Neighborhood Hits	115	Shared Neighborhood Hits	26
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.183829 (rank : 21)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	43	Target Neighborhood Hits	109	Shared Neighborhood Hits	25
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

MNT_HUMAN
NC score	0.174868 (rank : 22)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	43	Target Neighborhood Hits	496	Shared Neighborhood Hits	23
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

TFE3_HUMAN
NC score	0.160439 (rank : 23)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	43	Target Neighborhood Hits	190	Shared Neighborhood Hits	31
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
NC score	0.158218 (rank : 24)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	43	Target Neighborhood Hits	113	Shared Neighborhood Hits	31
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
NC score	0.155810 (rank : 25)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	43	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MAD3_HUMAN
NC score	0.153789 (rank : 26)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	43	Target Neighborhood Hits	92	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BW11, Q53HK1, Q7Z4Y0, Q8NDJ7, Q96ME3	Gene names	MXD3, MAD3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3) (Myx).

MAD3_MOUSE
NC score	0.152605 (rank : 27)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	43	Target Neighborhood Hits	94	Shared Neighborhood Hits	19
SwissProt Accessions	Q80US8, Q60947	Gene names	Mxd3, Mad3
Domain Architecture	No domain graphic available
Description	Max-interacting transcriptional repressor MAD3 (Max-associated protein 3) (MAX dimerization protein 3).

MAD4_MOUSE
NC score	0.152343 (rank : 28)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	43	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q60948	Gene names	Mxd4, Mad4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MAX_MOUSE
NC score	0.145998 (rank : 29)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	43	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

MAX_HUMAN
NC score	0.134367 (rank : 30)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	43	Target Neighborhood Hits	125	Shared Neighborhood Hits	27
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

CLOCK_MOUSE
NC score	0.132758 (rank : 31)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	43	Target Neighborhood Hits	148	Shared Neighborhood Hits	20
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.130633 (rank : 32)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	43	Target Neighborhood Hits	127	Shared Neighborhood Hits	20
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

NPAS2_HUMAN
NC score	0.129367 (rank : 33)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	43	Target Neighborhood Hits	150	Shared Neighborhood Hits	23
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
NC score	0.127927 (rank : 34)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	43	Target Neighborhood Hits	132	Shared Neighborhood Hits	22
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

EPAS1_HUMAN
NC score	0.078977 (rank : 35)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
NC score	0.078190 (rank : 36)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	43	Target Neighborhood Hits	94	Shared Neighborhood Hits	10
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HIF1A_HUMAN
NC score	0.075848 (rank : 37)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	43	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
NC score	0.075700 (rank : 38)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	43	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

HEY2_HUMAN
NC score	0.070499 (rank : 39)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	43	Target Neighborhood Hits	77	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

MYC_MOUSE
NC score	0.070245 (rank : 40)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	43	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	P01108, P70247, Q3UM70, Q61422	Gene names	Myc
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

SIM2_HUMAN
NC score	0.070143 (rank : 41)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	43	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

MYCL1_MOUSE
NC score	0.070082 (rank : 42)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	43	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

SIM1_MOUSE
NC score	0.069764 (rank : 43)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	43	Target Neighborhood Hits	69	Shared Neighborhood Hits	10
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM1_HUMAN
NC score	0.069678 (rank : 44)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	43	Target Neighborhood Hits	62	Shared Neighborhood Hits	10
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM2_MOUSE
NC score	0.068799 (rank : 45)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	43	Target Neighborhood Hits	75	Shared Neighborhood Hits	10
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

WBS14_HUMAN
NC score	0.068592 (rank : 46)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	43	Target Neighborhood Hits	273	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NP71, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9Y2P3	Gene names	MLXIPL, MIO, WBSCR14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein (WS basic-helix- loop-helix leucine zipper protein) (WS-bHLH) (Mlx interactor) (MLX- interacting protein-like).

HEY2_MOUSE
NC score	0.068575 (rank : 47)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	43	Target Neighborhood Hits	80	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

AHR_HUMAN
NC score	0.068199 (rank : 48)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	43	Target Neighborhood Hits	47	Shared Neighborhood Hits	12
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

HEY1_MOUSE
NC score	0.068125 (rank : 49)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	43	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

SRBP1_HUMAN
NC score	0.067982 (rank : 50)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	43	Target Neighborhood Hits	225	Shared Neighborhood Hits	25
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MYC_HUMAN
NC score	0.067639 (rank : 51)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	43	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	P01106, P01107, Q14026	Gene names	MYC
Domain Architecture
Description	Myc proto-oncogene protein (c-Myc) (Transcription factor p64).

SRBP1_MOUSE
NC score	0.067114 (rank : 52)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	43	Target Neighborhood Hits	384	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

HEY1_HUMAN
NC score	0.065846 (rank : 53)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	43	Target Neighborhood Hits	82	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

MYCL1_HUMAN
NC score	0.065700 (rank : 54)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	43	Target Neighborhood Hits	146	Shared Neighborhood Hits	29
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

NPAS3_MOUSE
NC score	0.065597 (rank : 55)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	43	Target Neighborhood Hits	103	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

AHR_MOUSE
NC score	0.065126 (rank : 56)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	43	Target Neighborhood Hits	55	Shared Neighborhood Hits	10
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

K0310_HUMAN
NC score	0.065014 (rank : 57)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	43	Target Neighborhood Hits	420	Shared Neighborhood Hits	8
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

NPAS3_HUMAN
NC score	0.063824 (rank : 58)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	43	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

MYCN_HUMAN
NC score	0.062617 (rank : 59)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	43	Target Neighborhood Hits	127	Shared Neighborhood Hits	24
SwissProt Accessions	P04198, Q6LDT9	Gene names	MYCN, NMYC
Domain Architecture
Description	N-myc proto-oncogene protein.

NCOA1_MOUSE
NC score	0.062117 (rank : 60)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	43	Target Neighborhood Hits	196	Shared Neighborhood Hits	16
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

MYCN_MOUSE
NC score	0.062015 (rank : 61)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	43	Target Neighborhood Hits	125	Shared Neighborhood Hits	22
SwissProt Accessions	P03966, Q61978	Gene names	Mycn, Nmyc, Nmyc1
Domain Architecture
Description	N-myc proto-oncogene protein.

NCOA1_HUMAN
NC score	0.062012 (rank : 62)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	43	Target Neighborhood Hits	198	Shared Neighborhood Hits	15
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

SRBP2_HUMAN
NC score	0.060946 (rank : 63)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	43	Target Neighborhood Hits	133	Shared Neighborhood Hits	26
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

NPAS1_MOUSE
NC score	0.060532 (rank : 64)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	43	Target Neighborhood Hits	63	Shared Neighborhood Hits	10
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.060381 (rank : 65)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	43	Target Neighborhood Hits	77	Shared Neighborhood Hits	12
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

PER2_HUMAN
NC score	0.059229 (rank : 66)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	43	Target Neighborhood Hits	170	Shared Neighborhood Hits	13
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

NCOA3_HUMAN
NC score	0.059109 (rank : 67)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	43	Target Neighborhood Hits	171	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

PER3_MOUSE
NC score	0.059061 (rank : 68)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	43	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_MOUSE
NC score	0.058812 (rank : 69)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	43	Target Neighborhood Hits	325	Shared Neighborhood Hits	15
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

BHLH3_HUMAN
NC score	0.056871 (rank : 70)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	43	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

PER1_MOUSE
NC score	0.056786 (rank : 71)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	43	Target Neighborhood Hits	235	Shared Neighborhood Hits	13
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

WBS14_MOUSE
NC score	0.056333 (rank : 72)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	43	Target Neighborhood Hits	171	Shared Neighborhood Hits	12
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

PER1_HUMAN
NC score	0.055475 (rank : 73)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	43	Target Neighborhood Hits	215	Shared Neighborhood Hits	12
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER3_HUMAN
NC score	0.055197 (rank : 74)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	43	Target Neighborhood Hits	479	Shared Neighborhood Hits	11
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

TFAP4_HUMAN
NC score	0.054856 (rank : 75)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	43	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

MYCS_MOUSE
NC score	0.054725 (rank : 76)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	43	Target Neighborhood Hits	83	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

BHLH3_MOUSE
NC score	0.054346 (rank : 77)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

NCOA3_MOUSE
NC score	0.051627 (rank : 78)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	43	Target Neighborhood Hits	203	Shared Neighborhood Hits	10
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PHAR1_MOUSE
NC score	0.038505 (rank : 79)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	43	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q2M3X8, Q80VL9, Q8C873	Gene names	Phactr1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 1.

MAP1B_MOUSE
NC score	0.033651 (rank : 80)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	43	Target Neighborhood Hits	977	Shared Neighborhood Hits	10
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

PHAR1_HUMAN
NC score	0.032707 (rank : 81)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	43	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	Q9C0D0, Q3MJ93, Q5JSJ2	Gene names	PHACTR1, KIAA1733, RPEL1
Domain Architecture
Description	Phosphatase and actin regulator 1.

DCP1A_HUMAN
NC score	0.027546 (rank : 82)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	43	Target Neighborhood Hits	228	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

PDXL2_MOUSE
NC score	0.025818 (rank : 83)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	43	Target Neighborhood Hits	213	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

IER5_MOUSE
NC score	0.023890 (rank : 84)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	43	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

HAIR_HUMAN
NC score	0.022914 (rank : 85)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	43	Target Neighborhood Hits	172	Shared Neighborhood Hits	3
SwissProt Accessions	O43593, Q96H33, Q9NPE1	Gene names	HR
Domain Architecture
Description	Protein hairless.

TTC16_HUMAN
NC score	0.022821 (rank : 86)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	43	Target Neighborhood Hits	417	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

NALDL_HUMAN
NC score	0.022089 (rank : 87)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	43	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UQQ1, O43176	Gene names	NAALADL1, NAALADASEL, NAALADL
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).

MAP1A_HUMAN
NC score	0.020804 (rank : 88)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	43	Target Neighborhood Hits	1626	Shared Neighborhood Hits	7
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PLRG1_HUMAN
NC score	0.007951 (rank : 89)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	43	Target Neighborhood Hits	318	Shared Neighborhood Hits	2
SwissProt Accessions	O43660, Q8WUD8	Gene names	PLRG1
Domain Architecture
Description	Pleiotropic regulator 1.