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Network neighborhood for query Sequence : CLOCK_MOUSE

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CLOCK_MOUSE
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CLOCK_HUMAN
θ value	0 (rank : 1)	NC score	0.993703 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	127	Shared Neighborhood Hits	106
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

CLOCK_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

NPAS2_HUMAN
θ value	0 (rank : 3)	NC score	0.967165 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	150	Shared Neighborhood Hits	72
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

NPAS2_MOUSE
θ value	0 (rank : 4)	NC score	0.967751 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	68
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

BMAL1_HUMAN
θ value	1.16164e-39 (rank : 5)	NC score	0.856373 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	62
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
θ value	5.76516e-39 (rank : 6)	NC score	0.852638 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

EPAS1_HUMAN
θ value	1.16434e-31 (rank : 7)	NC score	0.807894 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

ARNT_HUMAN
θ value	4.42448e-31 (rank : 8)	NC score	0.810328 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	63
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	4.42448e-31 (rank : 9)	NC score	0.795993 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

HIF1A_HUMAN
θ value	3.17079e-29 (rank : 10)	NC score	0.800620 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	118	Shared Neighborhood Hits	41
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

EPAS1_MOUSE
θ value	4.14116e-29 (rank : 11)	NC score	0.803980 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HIF1A_MOUSE
θ value	5.97985e-28 (rank : 12)	NC score	0.798932 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

ARNT2_MOUSE
θ value	1.37858e-24 (rank : 13)	NC score	0.796400 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	62
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
θ value	2.35151e-24 (rank : 14)	NC score	0.796005 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

SIM1_MOUSE
θ value	1.99067e-23 (rank : 15)	NC score	0.761162 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	69	Shared Neighborhood Hits	43
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM1_HUMAN
θ value	5.79196e-23 (rank : 16)	NC score	0.761158 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	62	Shared Neighborhood Hits	43
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM2_HUMAN
θ value	2.20094e-22 (rank : 17)	NC score	0.757698 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
θ value	4.9032e-22 (rank : 18)	NC score	0.756072 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

AHR_MOUSE
θ value	1.2077e-20 (rank : 19)	NC score	0.742730 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_HUMAN
θ value	4.58923e-20 (rank : 20)	NC score	0.750577 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NCOA2_HUMAN
θ value	4.29542e-18 (rank : 21)	NC score	0.602275 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	281	Shared Neighborhood Hits	43
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
θ value	4.29542e-18 (rank : 22)	NC score	0.600761 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NPAS3_MOUSE
θ value	4.29542e-18 (rank : 23)	NC score	0.721052 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
θ value	9.56915e-18 (rank : 24)	NC score	0.717795 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NCOA1_HUMAN
θ value	1.38178e-16 (rank : 25)	NC score	0.650948 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	1.38178e-16 (rank : 26)	NC score	0.653957 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	196	Shared Neighborhood Hits	47
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA3_HUMAN
θ value	9.90251e-15 (rank : 27)	NC score	0.605117 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	171	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NPAS1_MOUSE
θ value	2.20605e-14 (rank : 28)	NC score	0.704600 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
θ value	3.76295e-14 (rank : 29)	NC score	0.701195 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NCOA3_MOUSE
θ value	3.89403e-11 (rank : 30)	NC score	0.563509 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

PER3_MOUSE
θ value	4.76016e-09 (rank : 31)	NC score	0.427137 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_MOUSE
θ value	1.38499e-08 (rank : 32)	NC score	0.382767 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	325	Shared Neighborhood Hits	29
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER3_HUMAN
θ value	6.87365e-08 (rank : 33)	NC score	0.388430 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	479	Shared Neighborhood Hits	38
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_HUMAN
θ value	4.45536e-07 (rank : 34)	NC score	0.401413 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_HUMAN
θ value	2.21117e-06 (rank : 35)	NC score	0.393600 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	215	Shared Neighborhood Hits	37
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
θ value	2.21117e-06 (rank : 36)	NC score	0.389896 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

NPAS4_HUMAN
θ value	8.40245e-06 (rank : 37)	NC score	0.528483 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	214	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	1.43324e-05 (rank : 38)	NC score	0.514009 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	245	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

TFE3_HUMAN
θ value	7.1131e-05 (rank : 39)	NC score	0.235685 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	190	Shared Neighborhood Hits	41
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_HUMAN
θ value	0.000461057 (rank : 40)	NC score	0.226680 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	0.000602161 (rank : 41)	NC score	0.227693 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MLX_HUMAN
θ value	0.00228821 (rank : 42)	NC score	0.195161 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

SRBP1_MOUSE
θ value	0.00228821 (rank : 43)	NC score	0.153676 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP1_HUMAN
θ value	0.00298849 (rank : 44)	NC score	0.165606 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	225	Shared Neighborhood Hits	41
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MLX_MOUSE
θ value	0.00390308 (rank : 45)	NC score	0.196144 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

TFEB_HUMAN
θ value	0.00390308 (rank : 46)	NC score	0.210108 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	0.00390308 (rank : 47)	NC score	0.211072 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

SRBP2_HUMAN
θ value	0.00665767 (rank : 48)	NC score	0.146642 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	39
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

NFAT5_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.046176 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

ZN185_HUMAN
θ value	0.0252991 (rank : 50)	NC score	0.067458 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

MLL2_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.043134 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	1788	Shared Neighborhood Hits	56
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ZBT24_MOUSE
θ value	0.0736092 (rank : 52)	NC score	-0.000342 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	894	Shared Neighborhood Hits	13
SwissProt Accessions	Q80X44, Q3UIB7, Q7TPC4, Q8CJC9	Gene names	Zbtb24, Bif1, Bsg1, Znf450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450) (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1).

CCD91_MOUSE
θ value	0.0961366 (rank : 53)	NC score	0.036000 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	699	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CDKL5_HUMAN
θ value	0.0961366 (rank : 54)	NC score	-0.000981 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	967	Shared Neighborhood Hits	4
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

PCQAP_HUMAN
θ value	0.0961366 (rank : 55)	NC score	0.069016 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	549	Shared Neighborhood Hits	41
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

HNF1B_MOUSE
θ value	0.125558 (rank : 56)	NC score	0.036426 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

MYH9_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.030186 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	1762	Shared Neighborhood Hits	48
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	0.163984 (rank : 58)	NC score	0.029362 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	1829	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SP3_HUMAN
θ value	0.21417 (rank : 59)	NC score	0.005001 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	737	Shared Neighborhood Hits	14
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

HEY2_HUMAN
θ value	0.279714 (rank : 60)	NC score	0.168126 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.165378 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

INVO_HUMAN
θ value	0.365318 (rank : 62)	NC score	0.031044 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	636	Shared Neighborhood Hits	37
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

DCP1A_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.050568 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

HEY1_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.162368 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	0.47712 (rank : 65)	NC score	0.167419 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

K0423_MOUSE
θ value	0.47712 (rank : 66)	NC score	0.027692 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

NCOA6_HUMAN
θ value	0.47712 (rank : 67)	NC score	0.060456 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	1202	Shared Neighborhood Hits	44
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RUFY2_HUMAN
θ value	0.47712 (rank : 68)	NC score	0.030311 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	1208	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RUFY2_MOUSE
θ value	0.47712 (rank : 69)	NC score	0.032475 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	820	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SP3_MOUSE
θ value	0.47712 (rank : 70)	NC score	0.004693 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	O70494, Q68FF2, Q8CF64, Q8K378	Gene names	Sp3
Domain Architecture	No domain graphic available
Description	Transcription factor Sp3.

TNC6B_HUMAN
θ value	0.47712 (rank : 71)	NC score	0.038805 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	256	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

NFKB2_HUMAN
θ value	0.62314 (rank : 72)	NC score	0.019427 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NFKB2_MOUSE
θ value	0.62314 (rank : 73)	NC score	0.018988 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

DACT1_HUMAN
θ value	0.813845 (rank : 74)	NC score	0.036040 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

HNF1B_HUMAN
θ value	0.813845 (rank : 75)	NC score	0.035509 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

MAX_MOUSE
θ value	0.813845 (rank : 76)	NC score	0.115347 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

ATX2L_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.026776 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	443	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

EMIL3_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.036436 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

HES5_MOUSE
θ value	1.06291 (rank : 79)	NC score	0.117486 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

MLL3_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.035702 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	1644	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYH11_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.023915 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	1806	Shared Neighborhood Hits	47
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	1.06291 (rank : 82)	NC score	0.023602 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	1777	Shared Neighborhood Hits	43
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

AKAP1_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.017873 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

BHLH3_HUMAN
θ value	1.38821 (rank : 84)	NC score	0.117387 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
θ value	1.38821 (rank : 85)	NC score	0.115418 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

INVO_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.028994 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	474	Shared Neighborhood Hits	29
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

MYH10_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.024737 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	1620	Shared Neighborhood Hits	45
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.024513 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	1612	Shared Neighborhood Hits	44
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RUFY1_HUMAN
θ value	1.38821 (rank : 89)	NC score	0.030731 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	848	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

ZEP1_MOUSE
θ value	1.38821 (rank : 90)	NC score	0.006585 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	1063	Shared Neighborhood Hits	21
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

HES3_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.086471 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

PARP1_MOUSE
θ value	1.81305 (rank : 92)	NC score	0.018144 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PKNX2_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.012678 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

REL_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.021055 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

RPTN_MOUSE
θ value	1.81305 (rank : 95)	NC score	0.016375 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SMRC1_HUMAN
θ value	1.81305 (rank : 96)	NC score	0.012942 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	375	Shared Neighborhood Hits	17
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

BHLH2_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.109400 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.107885 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

MYH14_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.021883 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	1225	Shared Neighborhood Hits	34
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYOC_MOUSE
θ value	2.36792 (rank : 100)	NC score	0.016641 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	232	Shared Neighborhood Hits	17
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

RUFY1_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.025927 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	765	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

SH24A_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.024368 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	326	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

ATX2L_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.023895 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	401	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

MAX_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.101234 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

PP16A_MOUSE
θ value	3.0926 (rank : 105)	NC score	0.003906 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	318	Shared Neighborhood Hits	7
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

TCFL5_HUMAN
θ value	3.0926 (rank : 106)	NC score	0.132758 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

ANR26_MOUSE
θ value	4.03905 (rank : 107)	NC score	0.013006 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	1554	Shared Neighborhood Hits	44
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

C8AP2_MOUSE
θ value	4.03905 (rank : 108)	NC score	0.016071 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	405	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

DMD_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.015474 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	1111	Shared Neighborhood Hits	31
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

HCN1_MOUSE
θ value	4.03905 (rank : 110)	NC score	0.012176 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	172	Shared Neighborhood Hits	15
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

MYCL1_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.087227 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.092621 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

PKNX2_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.010433 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

UACA_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.012320 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	1622	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ZBTB4_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.003071 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	926	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

CENPE_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.011748 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	2060	Shared Neighborhood Hits	48
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CENPF_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.012816 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	1932	Shared Neighborhood Hits	46
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CENPQ_HUMAN
θ value	5.27518 (rank : 118)	NC score	0.027729 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

ETV5_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.005862 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	328	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

MDC1_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.016924 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	1446	Shared Neighborhood Hits	43
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MUC5B_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.017244 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	1020	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SAFB2_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.013628 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	720	Shared Neighborhood Hits	28
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SC24A_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.021431 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SH24A_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.021100 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

WNK1_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.001824 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	1179	Shared Neighborhood Hits	26
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

CP250_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.013022 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	1805	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DMD_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.014867 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	1135	Shared Neighborhood Hits	31
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

EMIL3_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.029687 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

EMSY_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.053289 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	296	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

EMSY_MOUSE
θ value	6.88961 (rank : 130)	NC score	0.050153 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	294	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

GOGA5_MOUSE
θ value	6.88961 (rank : 131)	NC score	0.016093 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	1434	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

KIF3A_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.006049 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYO10_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.018700 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	920	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PCQAP_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.035893 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	506	Shared Neighborhood Hits	39
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

TANK_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.011725 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q92844, Q92885	Gene names	TANK, ITRAF
Domain Architecture
Description	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF).

TFAP4_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.051301 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TPR_HUMAN
θ value	6.88961 (rank : 137)	NC score	0.014354 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	1921	Shared Neighborhood Hits	49
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

UBQL2_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.006682 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

ALO17_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.007439 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	317	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

ATF2_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.009209 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

BMF_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.015662 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LC9, Q2M396, Q6NT30, Q6NT56, Q6P9F6, Q7Z7D4, Q7Z7D5, Q9H7K7	Gene names	BMF
Domain Architecture	No domain graphic available
Description	Bcl-2-modifying factor.

CE110_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.008574 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

EGR3_HUMAN
θ value	8.99809 (rank : 143)	NC score	-0.001149 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	746	Shared Neighborhood Hits	11
SwissProt Accessions	Q06889	Gene names	EGR3, PILOT
Domain Architecture	No domain graphic available
Description	Early growth response protein 3 (EGR-3) (Zinc finger protein pilot).

EGR3_MOUSE
θ value	8.99809 (rank : 144)	NC score	-0.001137 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	P43300, Q9R276	Gene names	Egr3, Egr-3
Domain Architecture
Description	Early growth response protein 3 (EGR-3).

GON4L_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.017661 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	555	Shared Neighborhood Hits	25
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

NCOA6_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.065462 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	1076	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

SETBP_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.016218 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

ZBT16_HUMAN
θ value	8.99809 (rank : 148)	NC score	-0.003132 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	1010	Shared Neighborhood Hits	11
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

HES1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.060523 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	24
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.060693 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES4_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.067138 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

HES7_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.077631 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.073398 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MAD4_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.060036 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	24
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

MYCS_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.050185 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

USF1_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.138542 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.138690 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.132895 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	155	Shared Neighborhood Hits	36
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.126657 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

Hits sorted by NC score

CLOCK_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	148	Target Neighborhood Hits	148	Shared Neighborhood Hits	148
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.993703 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	148	Target Neighborhood Hits	127	Shared Neighborhood Hits	106
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

NPAS2_MOUSE
NC score	0.967751 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	148	Target Neighborhood Hits	132	Shared Neighborhood Hits	68
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
NC score	0.967165 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	148	Target Neighborhood Hits	150	Shared Neighborhood Hits	72
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

BMAL1_HUMAN
NC score	0.856373 (rank : 5)	θ value	1.16164e-39 (rank : 5)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	62
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

BMAL1_MOUSE
NC score	0.852638 (rank : 6)	θ value	5.76516e-39 (rank : 6)
Query Neighborhood Hits	148	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

ARNT_HUMAN
NC score	0.810328 (rank : 7)	θ value	4.42448e-31 (rank : 8)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	63
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

EPAS1_HUMAN
NC score	0.807894 (rank : 8)	θ value	1.16434e-31 (rank : 7)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	38
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

EPAS1_MOUSE
NC score	0.803980 (rank : 9)	θ value	4.14116e-29 (rank : 11)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	39
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

HIF1A_HUMAN
NC score	0.800620 (rank : 10)	θ value	3.17079e-29 (rank : 10)
Query Neighborhood Hits	148	Target Neighborhood Hits	118	Shared Neighborhood Hits	41
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
NC score	0.798932 (rank : 11)	θ value	5.97985e-28 (rank : 12)
Query Neighborhood Hits	148	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

ARNT2_MOUSE
NC score	0.796400 (rank : 12)	θ value	1.37858e-24 (rank : 13)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	62
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.796005 (rank : 13)	θ value	2.35151e-24 (rank : 14)
Query Neighborhood Hits	148	Target Neighborhood Hits	109	Shared Neighborhood Hits	61
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_MOUSE
NC score	0.795993 (rank : 14)	θ value	4.42448e-31 (rank : 9)
Query Neighborhood Hits	148	Target Neighborhood Hits	213	Shared Neighborhood Hits	66
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

SIM1_MOUSE
NC score	0.761162 (rank : 15)	θ value	1.99067e-23 (rank : 15)
Query Neighborhood Hits	148	Target Neighborhood Hits	69	Shared Neighborhood Hits	43
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM1_HUMAN
NC score	0.761158 (rank : 16)	θ value	5.79196e-23 (rank : 16)
Query Neighborhood Hits	148	Target Neighborhood Hits	62	Shared Neighborhood Hits	43
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM2_HUMAN
NC score	0.757698 (rank : 17)	θ value	2.20094e-22 (rank : 17)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	43
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

SIM2_MOUSE
NC score	0.756072 (rank : 18)	θ value	4.9032e-22 (rank : 18)
Query Neighborhood Hits	148	Target Neighborhood Hits	75	Shared Neighborhood Hits	40
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

AHR_HUMAN
NC score	0.750577 (rank : 19)	θ value	4.58923e-20 (rank : 20)
Query Neighborhood Hits	148	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_MOUSE
NC score	0.742730 (rank : 20)	θ value	1.2077e-20 (rank : 19)
Query Neighborhood Hits	148	Target Neighborhood Hits	55	Shared Neighborhood Hits	36
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NPAS3_MOUSE
NC score	0.721052 (rank : 21)	θ value	4.29542e-18 (rank : 23)
Query Neighborhood Hits	148	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS3_HUMAN
NC score	0.717795 (rank : 22)	θ value	9.56915e-18 (rank : 24)
Query Neighborhood Hits	148	Target Neighborhood Hits	81	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

NPAS1_MOUSE
NC score	0.704600 (rank : 23)	θ value	2.20605e-14 (rank : 28)
Query Neighborhood Hits	148	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
NC score	0.701195 (rank : 24)	θ value	3.76295e-14 (rank : 29)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NCOA1_MOUSE
NC score	0.653957 (rank : 25)	θ value	1.38178e-16 (rank : 26)
Query Neighborhood Hits	148	Target Neighborhood Hits	196	Shared Neighborhood Hits	47
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.650948 (rank : 26)	θ value	1.38178e-16 (rank : 25)
Query Neighborhood Hits	148	Target Neighborhood Hits	198	Shared Neighborhood Hits	49
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA3_HUMAN
NC score	0.605117 (rank : 27)	θ value	9.90251e-15 (rank : 27)
Query Neighborhood Hits	148	Target Neighborhood Hits	171	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA2_HUMAN
NC score	0.602275 (rank : 28)	θ value	4.29542e-18 (rank : 21)
Query Neighborhood Hits	148	Target Neighborhood Hits	281	Shared Neighborhood Hits	43
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
NC score	0.600761 (rank : 29)	θ value	4.29542e-18 (rank : 22)
Query Neighborhood Hits	148	Target Neighborhood Hits	281	Shared Neighborhood Hits	42
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_MOUSE
NC score	0.563509 (rank : 30)	θ value	3.89403e-11 (rank : 30)
Query Neighborhood Hits	148	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

NPAS4_HUMAN
NC score	0.528483 (rank : 31)	θ value	8.40245e-06 (rank : 37)
Query Neighborhood Hits	148	Target Neighborhood Hits	214	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.514009 (rank : 32)	θ value	1.43324e-05 (rank : 38)
Query Neighborhood Hits	148	Target Neighborhood Hits	245	Shared Neighborhood Hits	46
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PER3_MOUSE
NC score	0.427137 (rank : 33)	θ value	4.76016e-09 (rank : 31)
Query Neighborhood Hits	148	Target Neighborhood Hits	85	Shared Neighborhood Hits	29
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER2_HUMAN
NC score	0.401413 (rank : 34)	θ value	4.45536e-07 (rank : 34)
Query Neighborhood Hits	148	Target Neighborhood Hits	170	Shared Neighborhood Hits	32
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_HUMAN
NC score	0.393600 (rank : 35)	θ value	2.21117e-06 (rank : 35)
Query Neighborhood Hits	148	Target Neighborhood Hits	215	Shared Neighborhood Hits	37
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER1_MOUSE
NC score	0.389896 (rank : 36)	θ value	2.21117e-06 (rank : 36)
Query Neighborhood Hits	148	Target Neighborhood Hits	235	Shared Neighborhood Hits	36
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER3_HUMAN
NC score	0.388430 (rank : 37)	θ value	6.87365e-08 (rank : 33)
Query Neighborhood Hits	148	Target Neighborhood Hits	479	Shared Neighborhood Hits	38
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_MOUSE
NC score	0.382767 (rank : 38)	θ value	1.38499e-08 (rank : 32)
Query Neighborhood Hits	148	Target Neighborhood Hits	325	Shared Neighborhood Hits	29
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

TFE3_HUMAN
NC score	0.235685 (rank : 39)	θ value	7.1131e-05 (rank : 39)
Query Neighborhood Hits	148	Target Neighborhood Hits	190	Shared Neighborhood Hits	41
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

MITF_MOUSE
NC score	0.227693 (rank : 40)	θ value	0.000602161 (rank : 41)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	39
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_HUMAN
NC score	0.226680 (rank : 41)	θ value	0.000461057 (rank : 40)
Query Neighborhood Hits	148	Target Neighborhood Hits	113	Shared Neighborhood Hits	39
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

TFEB_MOUSE
NC score	0.211072 (rank : 42)	θ value	0.00390308 (rank : 47)
Query Neighborhood Hits	148	Target Neighborhood Hits	119	Shared Neighborhood Hits	38
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.210108 (rank : 43)	θ value	0.00390308 (rank : 46)
Query Neighborhood Hits	148	Target Neighborhood Hits	111	Shared Neighborhood Hits	34
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

MLX_MOUSE
NC score	0.196144 (rank : 44)	θ value	0.00390308 (rank : 45)
Query Neighborhood Hits	148	Target Neighborhood Hits	100	Shared Neighborhood Hits	38
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_HUMAN
NC score	0.195161 (rank : 45)	θ value	0.00228821 (rank : 42)
Query Neighborhood Hits	148	Target Neighborhood Hits	95	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HEY2_HUMAN
NC score	0.168126 (rank : 46)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY1_MOUSE
NC score	0.167419 (rank : 47)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	148	Target Neighborhood Hits	69	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

SRBP1_HUMAN
NC score	0.165606 (rank : 48)	θ value	0.00298849 (rank : 44)
Query Neighborhood Hits	148	Target Neighborhood Hits	225	Shared Neighborhood Hits	41
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

HEY2_MOUSE
NC score	0.165378 (rank : 49)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	148	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_HUMAN
NC score	0.162368 (rank : 50)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	148	Target Neighborhood Hits	82	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

SRBP1_MOUSE
NC score	0.153676 (rank : 51)	θ value	0.00228821 (rank : 43)
Query Neighborhood Hits	148	Target Neighborhood Hits	384	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

SRBP2_HUMAN
NC score	0.146642 (rank : 52)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	39
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

USF1_MOUSE
NC score	0.138690 (rank : 53)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	148	Target Neighborhood Hits	71	Shared Neighborhood Hits	33
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_HUMAN
NC score	0.138542 (rank : 54)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	33
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
NC score	0.132895 (rank : 55)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	148	Target Neighborhood Hits	155	Shared Neighborhood Hits	36
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

TCFL5_HUMAN
NC score	0.132758 (rank : 56)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	148	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

USF2_MOUSE
NC score	0.126657 (rank : 57)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	148	Target Neighborhood Hits	173	Shared Neighborhood Hits	38
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

HES5_MOUSE
NC score	0.117486 (rank : 58)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

BHLH3_HUMAN
NC score	0.117387 (rank : 59)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	148	Target Neighborhood Hits	106	Shared Neighborhood Hits	33
SwissProt Accessions	Q9C0J9	Gene names	BHLHB3, DEC2, SHARP1
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1).

BHLH3_MOUSE
NC score	0.115418 (rank : 60)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	32
SwissProt Accessions	Q99PV5	Gene names	Bhlhb3, Dec2
Domain Architecture
Description	Class B basic helix-loop-helix protein 3 (bHLHB3) (Differentially expressed in chondrocytes protein 2) (mDEC2).

MAX_MOUSE
NC score	0.115347 (rank : 61)	θ value	0.813845 (rank : 76)
Query Neighborhood Hits	148	Target Neighborhood Hits	139	Shared Neighborhood Hits	37
SwissProt Accessions	P28574	Gene names	Max, Myn
Domain Architecture
Description	Protein max (Myc-associated factor X) (Protein myn) (Myc-binding novel HLH/LZ protein).

BHLH2_HUMAN
NC score	0.109400 (rank : 62)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	148	Target Neighborhood Hits	80	Shared Neighborhood Hits	32
SwissProt Accessions	O14503, Q96TD3	Gene names	BHLHB2, DEC1, SHARP2, STRA13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Differentially expressed in chondrocytes protein 1) (DEC1) (Enhancer-of-split and hairy-related protein 2) (SHARP-2) (Stimulated with retinoic acid 13).

BHLH2_MOUSE
NC score	0.107885 (rank : 63)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	148	Target Neighborhood Hits	70	Shared Neighborhood Hits	29
SwissProt Accessions	O35185, P97289	Gene names	Bhlhb2, Clast5, Stra13
Domain Architecture
Description	Class B basic helix-loop-helix protein 2 (bHLHB2) (Stimulated with retinoic acid 13) (E47 interaction protein 1) (eipl).

MAX_HUMAN
NC score	0.101234 (rank : 64)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	148	Target Neighborhood Hits	125	Shared Neighborhood Hits	35
SwissProt Accessions	P61244, P25912, P52163	Gene names	MAX
Domain Architecture
Description	Protein max (Myc-associated factor X).

MYCL1_MOUSE
NC score	0.092621 (rank : 65)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	148	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	P10166, Q5FWI7	Gene names	Mycl1, Lmyc1, Mycl
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

MYCL1_HUMAN
NC score	0.087227 (rank : 66)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	148	Target Neighborhood Hits	146	Shared Neighborhood Hits	30
SwissProt Accessions	P12524, Q14897, Q5QPL0, Q5QPL1, Q9NUE9	Gene names	MYCL1, LMYC, MYCL
Domain Architecture
Description	L-myc-1 proto-oncogene protein.

HES3_MOUSE
NC score	0.086471 (rank : 67)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	148	Target Neighborhood Hits	38	Shared Neighborhood Hits	16
SwissProt Accessions	Q61657, O09083, O09150	Gene names	Hes3, Hes-3
Domain Architecture
Description	Transcription factor HES-3 (Hairy and enhancer of split 3).

HES7_HUMAN
NC score	0.077631 (rank : 68)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	148	Target Neighborhood Hits	72	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
NC score	0.073398 (rank : 69)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	148	Target Neighborhood Hits	72	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

PCQAP_HUMAN
NC score	0.069016 (rank : 70)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	148	Target Neighborhood Hits	549	Shared Neighborhood Hits	41
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

ZN185_HUMAN
NC score	0.067458 (rank : 71)	θ value	0.0252991 (rank : 50)
Query Neighborhood Hits	148	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	O15231, O00345, Q9NSD2	Gene names	ZNF185
Domain Architecture
Description	Zinc finger protein 185 (LIM-domain protein ZNF185) (P1-A).

HES4_HUMAN
NC score	0.067138 (rank : 72)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	148	Target Neighborhood Hits	58	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

NCOA6_MOUSE
NC score	0.065462 (rank : 73)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	148	Target Neighborhood Hits	1076	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

HES1_MOUSE
NC score	0.060693 (rank : 74)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	148	Target Neighborhood Hits	78	Shared Neighborhood Hits	24
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.060523 (rank : 75)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	148	Target Neighborhood Hits	76	Shared Neighborhood Hits	24
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

NCOA6_HUMAN
NC score	0.060456 (rank : 76)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	148	Target Neighborhood Hits	1202	Shared Neighborhood Hits	44
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

MAD4_HUMAN
NC score	0.060036 (rank : 77)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	148	Target Neighborhood Hits	94	Shared Neighborhood Hits	24
SwissProt Accessions	Q14582, Q5TZX4	Gene names	MXD4, MAD4
Domain Architecture
Description	Max-interacting transcriptional repressor MAD4 (Max-associated protein 4) (MAX dimerization protein 4).

EMSY_HUMAN
NC score	0.053289 (rank : 78)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	148	Target Neighborhood Hits	296	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z589, Q4G109, Q8NBU6, Q8TE50, Q9H8I9, Q9NRH0	Gene names	EMSY, C11orf30
Domain Architecture
Description	Protein EMSY.

TFAP4_HUMAN
NC score	0.051301 (rank : 79)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	148	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

DCP1A_HUMAN
NC score	0.050568 (rank : 80)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	148	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

MYCS_MOUSE
NC score	0.050185 (rank : 81)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	148	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z304	Gene names	Mycs
Domain Architecture
Description	Protein S-myc.

EMSY_MOUSE
NC score	0.050153 (rank : 82)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	148	Target Neighborhood Hits	294	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

NFAT5_MOUSE
NC score	0.046176 (rank : 83)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	148	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WV30	Gene names	Nfat5
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T cell transcription factor NFAT5) (NF-AT5) (Rel domain-containing transcription factor NFAT5).

MLL2_HUMAN
NC score	0.043134 (rank : 84)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	148	Target Neighborhood Hits	1788	Shared Neighborhood Hits	56
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TNC6B_HUMAN
NC score	0.038805 (rank : 85)	θ value	0.47712 (rank : 71)
Query Neighborhood Hits	148	Target Neighborhood Hits	256	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

EMIL3_HUMAN
NC score	0.036436 (rank : 86)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	148	Target Neighborhood Hits	249	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NT22, Q76KT4	Gene names	EMILIN3, C20orf130, EMILIN5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface-located protein 5) (Elastin microfibril interfacer 5).

HNF1B_MOUSE
NC score	0.036426 (rank : 87)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	148	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	P27889, Q8R162, Q9CS26, Q9R1W1, Q9R1W2, Q9WTL5, Q9WTL6	Gene names	Tcf2, Hnf-1b, Hnf1b
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3).

DACT1_HUMAN
NC score	0.036040 (rank : 88)	θ value	0.813845 (rank : 74)
Query Neighborhood Hits	148	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

CCD91_MOUSE
NC score	0.036000 (rank : 89)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	148	Target Neighborhood Hits	699	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

PCQAP_MOUSE
NC score	0.035893 (rank : 90)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	148	Target Neighborhood Hits	506	Shared Neighborhood Hits	39
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

MLL3_HUMAN
NC score	0.035702 (rank : 91)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	148	Target Neighborhood Hits	1644	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

HNF1B_HUMAN
NC score	0.035509 (rank : 92)	θ value	0.813845 (rank : 75)
Query Neighborhood Hits	148	Target Neighborhood Hits	80	Shared Neighborhood Hits	13
SwissProt Accessions	P35680	Gene names	TCF2, HNF1B
Domain Architecture
Description	Hepatocyte nuclear factor 1-beta (HNF-1beta) (HNF-1B) (Variant hepatic nuclear factor 1) (VHNF1) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2).

RUFY2_MOUSE
NC score	0.032475 (rank : 93)	θ value	0.47712 (rank : 69)
Query Neighborhood Hits	148	Target Neighborhood Hits	820	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

INVO_HUMAN
NC score	0.031044 (rank : 94)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	148	Target Neighborhood Hits	636	Shared Neighborhood Hits	37
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

RUFY1_HUMAN
NC score	0.030731 (rank : 95)	θ value	1.38821 (rank : 89)
Query Neighborhood Hits	148	Target Neighborhood Hits	848	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

RUFY2_HUMAN
NC score	0.030311 (rank : 96)	θ value	0.47712 (rank : 68)
Query Neighborhood Hits	148	Target Neighborhood Hits	1208	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MYH9_HUMAN
NC score	0.030186 (rank : 97)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	148	Target Neighborhood Hits	1762	Shared Neighborhood Hits	48
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

EMIL3_MOUSE
NC score	0.029687 (rank : 98)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	148	Target Neighborhood Hits	240	Shared Neighborhood Hits	21
SwissProt Accessions	P59900	Gene names	Emilin3, Emilin5
Domain Architecture	No domain graphic available
Description	EMILIN-3 precursor (EMILIN-5) (Elastin microfibril interface located protein 5) (Elastin microfibril interfacer 5).

MYH9_MOUSE
NC score	0.029362 (rank : 99)	θ value	0.163984 (rank : 58)
Query Neighborhood Hits	148	Target Neighborhood Hits	1829	Shared Neighborhood Hits	48
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

INVO_MOUSE
NC score	0.028994 (rank : 100)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	148	Target Neighborhood Hits	474	Shared Neighborhood Hits	29
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

CENPQ_HUMAN
NC score	0.027729 (rank : 101)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	148	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q7L2Z9, Q6IN61, Q9NVS5	Gene names	CENPQ, C6orf139
Domain Architecture	No domain graphic available
Description	Centromere protein Q (CENP-Q).

K0423_MOUSE
NC score	0.027692 (rank : 102)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	148	Target Neighborhood Hits	115	Shared Neighborhood Hits	4
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

ATX2L_HUMAN
NC score	0.026776 (rank : 103)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	148	Target Neighborhood Hits	443	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

RUFY1_MOUSE
NC score	0.025927 (rank : 104)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	148	Target Neighborhood Hits	765	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

MYH10_HUMAN
NC score	0.024737 (rank : 105)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	148	Target Neighborhood Hits	1620	Shared Neighborhood Hits	45
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.024513 (rank : 106)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	148	Target Neighborhood Hits	1612	Shared Neighborhood Hits	44
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SH24A_MOUSE
NC score	0.024368 (rank : 107)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	148	Target Neighborhood Hits	326	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D7V1	Gene names	Sh2d4a
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A.

MYH11_HUMAN
NC score	0.023915 (rank : 108)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	148	Target Neighborhood Hits	1806	Shared Neighborhood Hits	47
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

ATX2L_MOUSE
NC score	0.023895 (rank : 109)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	148	Target Neighborhood Hits	401	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

MYH11_MOUSE
NC score	0.023602 (rank : 110)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	148	Target Neighborhood Hits	1777	Shared Neighborhood Hits	43
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH14_MOUSE
NC score	0.021883 (rank : 111)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	148	Target Neighborhood Hits	1225	Shared Neighborhood Hits	34
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

SC24A_MOUSE
NC score	0.021431 (rank : 112)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	148	Target Neighborhood Hits	394	Shared Neighborhood Hits	16
SwissProt Accessions	Q3U2P1, Q3TQ05, Q3TRG7, Q8BIS0	Gene names	Sec24a
Domain Architecture	No domain graphic available
Description	Protein transport protein Sec24A (SEC24-related protein A).

SH24A_HUMAN
NC score	0.021100 (rank : 113)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	148	Target Neighborhood Hits	455	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

REL_MOUSE
NC score	0.021055 (rank : 114)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	148	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

NFKB2_HUMAN
NC score	0.019427 (rank : 115)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	148	Target Neighborhood Hits	325	Shared Neighborhood Hits	9
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NFKB2_MOUSE
NC score	0.018988 (rank : 116)	θ value	0.62314 (rank : 73)
Query Neighborhood Hits	148	Target Neighborhood Hits	326	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

MYO10_HUMAN
NC score	0.018700 (rank : 117)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	148	Target Neighborhood Hits	920	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PARP1_MOUSE
NC score	0.018144 (rank : 118)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	148	Target Neighborhood Hits	102	Shared Neighborhood Hits	4
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

AKAP1_HUMAN
NC score	0.017873 (rank : 119)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	148	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	Q92667, Q13320, Q9BW14	Gene names	AKAP1, AKAP149
Domain Architecture
Description	A kinase anchor protein 1, mitochondrial precursor (Protein kinase A- anchoring protein 1) (PRKA1) (A-kinase anchor protein 149 kDa) (AKAP 149) (Dual specificity A-kinase-anchoring protein 1) (D-AKAP-1) (Spermatid A-kinase anchor protein 84) (S-AKAP84).

GON4L_HUMAN
NC score	0.017661 (rank : 120)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	148	Target Neighborhood Hits	555	Shared Neighborhood Hits	25
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

MUC5B_HUMAN
NC score	0.017244 (rank : 121)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	148	Target Neighborhood Hits	1020	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MDC1_HUMAN
NC score	0.016924 (rank : 122)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	148	Target Neighborhood Hits	1446	Shared Neighborhood Hits	43
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYOC_MOUSE
NC score	0.016641 (rank : 123)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	148	Target Neighborhood Hits	232	Shared Neighborhood Hits	17
SwissProt Accessions	O70624, O70289	Gene names	Myoc, Tigr
Domain Architecture
Description	Myocilin precursor (Trabecular meshwork-induced glucocorticoid response protein).

RPTN_MOUSE
NC score	0.016375 (rank : 124)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	148	Target Neighborhood Hits	650	Shared Neighborhood Hits	22
SwissProt Accessions	P97347	Gene names	Rptn
Domain Architecture
Description	Repetin.

SETBP_MOUSE
NC score	0.016218 (rank : 125)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	148	Target Neighborhood Hits	352	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z180, Q66JL8	Gene names	Setbp1, Kiaa0437
Domain Architecture	No domain graphic available
Description	SET-binding protein (SEB).

GOGA5_MOUSE
NC score	0.016093 (rank : 126)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	148	Target Neighborhood Hits	1434	Shared Neighborhood Hits	41
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

C8AP2_MOUSE
NC score	0.016071 (rank : 127)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	148	Target Neighborhood Hits	405	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WUF3, Q9CSW2	Gene names	Casp8ap2, Flash
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

BMF_HUMAN
NC score	0.015662 (rank : 128)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	148	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LC9, Q2M396, Q6NT30, Q6NT56, Q6P9F6, Q7Z7D4, Q7Z7D5, Q9H7K7	Gene names	BMF
Domain Architecture	No domain graphic available
Description	Bcl-2-modifying factor.

DMD_MOUSE
NC score	0.015474 (rank : 129)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	148	Target Neighborhood Hits	1111	Shared Neighborhood Hits	31
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DMD_HUMAN
NC score	0.014867 (rank : 130)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	148	Target Neighborhood Hits	1135	Shared Neighborhood Hits	31
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

TPR_HUMAN
NC score	0.014354 (rank : 131)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	148	Target Neighborhood Hits	1921	Shared Neighborhood Hits	49
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

SAFB2_HUMAN
NC score	0.013628 (rank : 132)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	148	Target Neighborhood Hits	720	Shared Neighborhood Hits	28
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

CP250_HUMAN
NC score	0.013022 (rank : 133)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	148	Target Neighborhood Hits	1805	Shared Neighborhood Hits	48
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

ANR26_MOUSE
NC score	0.013006 (rank : 134)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	148	Target Neighborhood Hits	1554	Shared Neighborhood Hits	44
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SMRC1_HUMAN
NC score	0.012942 (rank : 135)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	148	Target Neighborhood Hits	375	Shared Neighborhood Hits	17
SwissProt Accessions	Q92922, Q6P172, Q8IWH2	Gene names	SMARCC1, BAF155
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155).

CENPF_HUMAN
NC score	0.012816 (rank : 136)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	148	Target Neighborhood Hits	1932	Shared Neighborhood Hits	46
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PKNX2_MOUSE
NC score	0.012678 (rank : 137)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	148	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BG99, Q8R4B0	Gene names	Pknox2, Prep2
Domain Architecture	No domain graphic available
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

UACA_HUMAN
NC score	0.012320 (rank : 138)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	148	Target Neighborhood Hits	1622	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

HCN1_MOUSE
NC score	0.012176 (rank : 139)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	148	Target Neighborhood Hits	172	Shared Neighborhood Hits	15
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

CENPE_HUMAN
NC score	0.011748 (rank : 140)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	148	Target Neighborhood Hits	2060	Shared Neighborhood Hits	48
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TANK_HUMAN
NC score	0.011725 (rank : 141)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	148	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q92844, Q92885	Gene names	TANK, ITRAF
Domain Architecture
Description	TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF).

PKNX2_HUMAN
NC score	0.010433 (rank : 142)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	148	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KN3, Q63HL6, Q86XD1	Gene names	PKNOX2, PREP2
Domain Architecture
Description	Homeobox protein PKNOX2 (PBX/knotted homeobox 2) (Homeobox protein PREP-2).

ATF2_HUMAN
NC score	0.009209 (rank : 143)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	148	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	P15336, Q13000	Gene names	ATF2, CREB2, CREBP1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-2 (Activating transcription factor 2) (cAMP response element-binding protein CRE- BP1) (HB16).

CE110_MOUSE
NC score	0.008574 (rank : 144)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	148	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

ALO17_HUMAN
NC score	0.007439 (rank : 145)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	148	Target Neighborhood Hits	317	Shared Neighborhood Hits	9
SwissProt Accessions	Q9HCF4, Q69YK7, Q8IWF4, Q8IZX1, Q8IZX2, Q8N406	Gene names	KIAA1618, ALO17
Domain Architecture	No domain graphic available
Description	Protein ALO17 (ALK lymphoma oligomerization partner on chromosome 17).

UBQL2_MOUSE
NC score	0.006682 (rank : 146)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	148	Target Neighborhood Hits	114	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

ZEP1_MOUSE
NC score	0.006585 (rank : 147)	θ value	1.38821 (rank : 90)
Query Neighborhood Hits	148	Target Neighborhood Hits	1063	Shared Neighborhood Hits	21
SwissProt Accessions	Q03172	Gene names	Hivep1, Cryabp1, Znf40
Domain Architecture
Description	Zinc finger protein 40 (Transcription factor alphaA-CRYBP1) (Alpha A- crystallin-binding protein I) (Alpha A-CRYBP1).

KIF3A_HUMAN
NC score	0.006049 (rank : 148)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	148	Target Neighborhood Hits	704	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

ETV5_MOUSE
NC score	0.005862 (rank : 149)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	148	Target Neighborhood Hits	328	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CXC9, Q3TG49, Q8C0F3, Q9JHB1	Gene names	Etv5
Domain Architecture	No domain graphic available
Description	ETS translocation variant 5.

SP3_HUMAN
NC score	0.005001 (rank : 150)	θ value	0.21417 (rank : 59)
Query Neighborhood Hits	148	Target Neighborhood Hits	737	Shared Neighborhood Hits	14
SwissProt Accessions	Q02447, Q8TD56, Q9BQR1	Gene names	SP3
Domain Architecture
Description	Transcription factor Sp3 (SPR-2).

SP3_MOUSE
NC score	0.004693 (rank : 151)	θ value	0.47712 (rank : 70)
Query Neighborhood Hits	148	Target Neighborhood Hits	731	Shared Neighborhood Hits	13
SwissProt Accessions	O70494, Q68FF2, Q8CF64, Q8K378	Gene names	Sp3
Domain Architecture	No domain graphic available
Description	Transcription factor Sp3.

PP16A_MOUSE
NC score	0.003906 (rank : 152)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	148	Target Neighborhood Hits	318	Shared Neighborhood Hits	7
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ZBTB4_HUMAN
NC score	0.003071 (rank : 153)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	148	Target Neighborhood Hits	926	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P1Z0, Q7Z697, Q86XJ4, Q8N4V8	Gene names	ZBTB4, KIAA1538
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 4 (KAISO-like zinc finger protein 1) (KAISO-L1).

WNK1_MOUSE
NC score	0.001824 (rank : 154)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	148	Target Neighborhood Hits	1179	Shared Neighborhood Hits	26
SwissProt Accessions	P83741	Gene names	Wnk1, Prkwnk1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1).

ZBT24_MOUSE
NC score	-0.000342 (rank : 155)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	148	Target Neighborhood Hits	894	Shared Neighborhood Hits	13
SwissProt Accessions	Q80X44, Q3UIB7, Q7TPC4, Q8CJC9	Gene names	Zbtb24, Bif1, Bsg1, Znf450
Domain Architecture	No domain graphic available
Description	Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450) (Bone morphogenetic protein-induced factor 1) (Brain-specific protein 1).

CDKL5_HUMAN
NC score	-0.000981 (rank : 156)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	148	Target Neighborhood Hits	967	Shared Neighborhood Hits	4
SwissProt Accessions	O76039, Q14198, Q5H985, Q9UJL6	Gene names	CDKL5, STK9
Domain Architecture
Description	Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine- protein kinase 9).

EGR3_MOUSE
NC score	-0.001137 (rank : 157)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	148	Target Neighborhood Hits	747	Shared Neighborhood Hits	11
SwissProt Accessions	P43300, Q9R276	Gene names	Egr3, Egr-3
Domain Architecture
Description	Early growth response protein 3 (EGR-3).

EGR3_HUMAN
NC score	-0.001149 (rank : 158)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	148	Target Neighborhood Hits	746	Shared Neighborhood Hits	11
SwissProt Accessions	Q06889	Gene names	EGR3, PILOT
Domain Architecture	No domain graphic available
Description	Early growth response protein 3 (EGR-3) (Zinc finger protein pilot).

ZBT16_HUMAN
NC score	-0.003132 (rank : 159)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	148	Target Neighborhood Hits	1010	Shared Neighborhood Hits	11
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).