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Network neighborhood for query Sequence : NCOA1_MOUSE

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NCOA1_MOUSE
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NCOA1_HUMAN
θ value	0 (rank : 1)	NC score	0.986315 (rank : 2)
Query Neighborhood Hits	196	Target Neighborhood Hits	198	Shared Neighborhood Hits	108
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	196	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA2_MOUSE
θ value	7.78761e-153 (rank : 3)	NC score	0.909492 (rank : 5)
Query Neighborhood Hits	196	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA2_HUMAN
θ value	1.7349e-152 (rank : 4)	NC score	0.910251 (rank : 4)
Query Neighborhood Hits	196	Target Neighborhood Hits	281	Shared Neighborhood Hits	52
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA3_HUMAN
θ value	2.36115e-125 (rank : 5)	NC score	0.912004 (rank : 3)
Query Neighborhood Hits	196	Target Neighborhood Hits	171	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA3_MOUSE
θ value	4.61877e-113 (rank : 6)	NC score	0.898766 (rank : 6)
Query Neighborhood Hits	196	Target Neighborhood Hits	203	Shared Neighborhood Hits	47
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

SIM1_HUMAN
θ value	1.13037e-18 (rank : 7)	NC score	0.642206 (rank : 10)
Query Neighborhood Hits	196	Target Neighborhood Hits	62	Shared Neighborhood Hits	38
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

SIM1_MOUSE
θ value	3.28887e-18 (rank : 8)	NC score	0.641130 (rank : 12)
Query Neighborhood Hits	196	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_MOUSE
θ value	5.60996e-18 (rank : 9)	NC score	0.636165 (rank : 13)
Query Neighborhood Hits	196	Target Neighborhood Hits	75	Shared Neighborhood Hits	38
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

CLOCK_MOUSE
θ value	1.38178e-16 (rank : 10)	NC score	0.653957 (rank : 7)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

BMAL1_HUMAN
θ value	2.35696e-16 (rank : 11)	NC score	0.644918 (rank : 9)
Query Neighborhood Hits	196	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

CLOCK_HUMAN
θ value	3.07829e-16 (rank : 12)	NC score	0.652972 (rank : 8)
Query Neighborhood Hits	196	Target Neighborhood Hits	127	Shared Neighborhood Hits	46
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

SIM2_HUMAN
θ value	5.25075e-16 (rank : 13)	NC score	0.633834 (rank : 15)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

NPAS2_MOUSE
θ value	6.85773e-16 (rank : 14)	NC score	0.632798 (rank : 16)
Query Neighborhood Hits	196	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
θ value	8.95645e-16 (rank : 15)	NC score	0.628594 (rank : 17)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	51
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

BMAL1_MOUSE
θ value	1.52774e-15 (rank : 16)	NC score	0.642078 (rank : 11)
Query Neighborhood Hits	196	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

ARNT2_HUMAN
θ value	7.58209e-15 (rank : 17)	NC score	0.610070 (rank : 25)
Query Neighborhood Hits	196	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_MOUSE
θ value	7.58209e-15 (rank : 18)	NC score	0.610391 (rank : 24)
Query Neighborhood Hits	196	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT_HUMAN
θ value	1.42992e-13 (rank : 19)	NC score	0.599347 (rank : 28)
Query Neighborhood Hits	196	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ARNT_MOUSE
θ value	2.43908e-13 (rank : 20)	NC score	0.590805 (rank : 30)
Query Neighborhood Hits	196	Target Neighborhood Hits	213	Shared Neighborhood Hits	58
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

HIF1A_HUMAN
θ value	5.43371e-13 (rank : 21)	NC score	0.624412 (rank : 19)
Query Neighborhood Hits	196	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

NPAS3_MOUSE
θ value	2.0648e-12 (rank : 22)	NC score	0.601608 (rank : 27)
Query Neighborhood Hits	196	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

HIF1A_MOUSE
θ value	2.69671e-12 (rank : 23)	NC score	0.623619 (rank : 20)
Query Neighborhood Hits	196	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

NPAS3_HUMAN
θ value	2.69671e-12 (rank : 24)	NC score	0.598693 (rank : 29)
Query Neighborhood Hits	196	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

AHR_MOUSE
θ value	6.00763e-12 (rank : 25)	NC score	0.625799 (rank : 18)
Query Neighborhood Hits	196	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

AHR_HUMAN
θ value	7.84624e-12 (rank : 26)	NC score	0.634284 (rank : 14)
Query Neighborhood Hits	196	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

NPAS1_MOUSE
θ value	7.84624e-12 (rank : 27)	NC score	0.611396 (rank : 23)
Query Neighborhood Hits	196	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

NPAS1_HUMAN
θ value	1.33837e-11 (rank : 28)	NC score	0.603229 (rank : 26)
Query Neighborhood Hits	196	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

EPAS1_MOUSE
θ value	3.89403e-11 (rank : 29)	NC score	0.620193 (rank : 21)
Query Neighborhood Hits	196	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
θ value	8.67504e-11 (rank : 30)	NC score	0.617030 (rank : 22)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

NPAS4_HUMAN
θ value	0.00102713 (rank : 31)	NC score	0.418035 (rank : 31)
Query Neighborhood Hits	196	Target Neighborhood Hits	214	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	0.00175202 (rank : 32)	NC score	0.410035 (rank : 32)
Query Neighborhood Hits	196	Target Neighborhood Hits	245	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

NCOA6_HUMAN
θ value	0.00298849 (rank : 33)	NC score	0.125210 (rank : 40)
Query Neighborhood Hits	196	Target Neighborhood Hits	1202	Shared Neighborhood Hits	83
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOA6_MOUSE
θ value	0.00509761 (rank : 34)	NC score	0.125737 (rank : 39)
Query Neighborhood Hits	196	Target Neighborhood Hits	1076	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NACAM_MOUSE
θ value	0.0563607 (rank : 35)	NC score	0.042245 (rank : 85)
Query Neighborhood Hits	196	Target Neighborhood Hits	1866	Shared Neighborhood Hits	83
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

LSM11_HUMAN
θ value	0.0736092 (rank : 36)	NC score	0.049652 (rank : 77)
Query Neighborhood Hits	196	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P83369, Q7Z7P0, Q8N975	Gene names	LSM11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

TRIO_HUMAN
θ value	0.0961366 (rank : 37)	NC score	0.007779 (rank : 181)
Query Neighborhood Hits	196	Target Neighborhood Hits	1580	Shared Neighborhood Hits	37
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

DSPP_HUMAN
θ value	0.125558 (rank : 38)	NC score	0.058500 (rank : 67)
Query Neighborhood Hits	196	Target Neighborhood Hits	645	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

RCOR3_MOUSE
θ value	0.125558 (rank : 39)	NC score	0.045631 (rank : 81)
Query Neighborhood Hits	196	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

PAX3_HUMAN
θ value	0.163984 (rank : 40)	NC score	0.013977 (rank : 145)
Query Neighborhood Hits	196	Target Neighborhood Hits	513	Shared Neighborhood Hits	21
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PCLO_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.052985 (rank : 73)
Query Neighborhood Hits	196	Target Neighborhood Hits	2275	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PER1_HUMAN
θ value	0.21417 (rank : 42)	NC score	0.161444 (rank : 33)
Query Neighborhood Hits	196	Target Neighborhood Hits	215	Shared Neighborhood Hits	40
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PRP2_MOUSE
θ value	0.21417 (rank : 43)	NC score	0.063958 (rank : 60)
Query Neighborhood Hits	196	Target Neighborhood Hits	347	Shared Neighborhood Hits	29
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

RNPS1_HUMAN
θ value	0.21417 (rank : 44)	NC score	0.033465 (rank : 101)
Query Neighborhood Hits	196	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
θ value	0.21417 (rank : 45)	NC score	0.033465 (rank : 102)
Query Neighborhood Hits	196	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

RU1C_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.068777 (rank : 58)
Query Neighborhood Hits	196	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
θ value	0.21417 (rank : 47)	NC score	0.068187 (rank : 59)
Query Neighborhood Hits	196	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RBBP6_MOUSE
θ value	0.279714 (rank : 48)	NC score	0.043536 (rank : 83)
Query Neighborhood Hits	196	Target Neighborhood Hits	1014	Shared Neighborhood Hits	43
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

AFAD_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.031818 (rank : 106)
Query Neighborhood Hits	196	Target Neighborhood Hits	689	Shared Neighborhood Hits	29
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

GGN_MOUSE
θ value	0.365318 (rank : 50)	NC score	0.040234 (rank : 87)
Query Neighborhood Hits	196	Target Neighborhood Hits	311	Shared Neighborhood Hits	25
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

RBM12_MOUSE
θ value	0.365318 (rank : 51)	NC score	0.053389 (rank : 72)
Query Neighborhood Hits	196	Target Neighborhood Hits	313	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SFRS4_MOUSE
θ value	0.365318 (rank : 52)	NC score	0.028375 (rank : 114)
Query Neighborhood Hits	196	Target Neighborhood Hits	406	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

WNK2_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.008330 (rank : 172)
Query Neighborhood Hits	196	Target Neighborhood Hits	1407	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

B4GT1_MOUSE
θ value	0.47712 (rank : 54)	NC score	0.020468 (rank : 131)
Query Neighborhood Hits	196	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

FOG2_HUMAN
θ value	0.47712 (rank : 55)	NC score	0.008344 (rank : 171)
Query Neighborhood Hits	196	Target Neighborhood Hits	731	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

PELP1_HUMAN
θ value	0.47712 (rank : 56)	NC score	0.048471 (rank : 79)
Query Neighborhood Hits	196	Target Neighborhood Hits	596	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PHLB1_HUMAN
θ value	0.47712 (rank : 57)	NC score	0.034204 (rank : 99)
Query Neighborhood Hits	196	Target Neighborhood Hits	1038	Shared Neighborhood Hits	62
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

RCOR3_HUMAN
θ value	0.47712 (rank : 58)	NC score	0.035108 (rank : 96)
Query Neighborhood Hits	196	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

UTX_HUMAN
θ value	0.47712 (rank : 59)	NC score	0.024442 (rank : 124)
Query Neighborhood Hits	196	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

AF9_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.061444 (rank : 65)
Query Neighborhood Hits	196	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

BPTF_HUMAN
θ value	0.62314 (rank : 61)	NC score	0.036673 (rank : 89)
Query Neighborhood Hits	196	Target Neighborhood Hits	786	Shared Neighborhood Hits	48
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DSPP_MOUSE
θ value	0.62314 (rank : 62)	NC score	0.039804 (rank : 88)
Query Neighborhood Hits	196	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

HES7_HUMAN
θ value	0.62314 (rank : 63)	NC score	0.096433 (rank : 47)
Query Neighborhood Hits	196	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

HES7_MOUSE
θ value	0.62314 (rank : 64)	NC score	0.092669 (rank : 50)
Query Neighborhood Hits	196	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MITF_HUMAN
θ value	0.62314 (rank : 65)	NC score	0.099038 (rank : 46)
Query Neighborhood Hits	196	Target Neighborhood Hits	113	Shared Neighborhood Hits	30
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_MOUSE
θ value	0.62314 (rank : 66)	NC score	0.101094 (rank : 45)
Query Neighborhood Hits	196	Target Neighborhood Hits	115	Shared Neighborhood Hits	32
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

ZEP1_HUMAN
θ value	0.62314 (rank : 67)	NC score	0.014007 (rank : 144)
Query Neighborhood Hits	196	Target Neighborhood Hits	1036	Shared Neighborhood Hits	38
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

AN32E_HUMAN
θ value	0.813845 (rank : 68)	NC score	0.029017 (rank : 112)
Query Neighborhood Hits	196	Target Neighborhood Hits	291	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

AN32E_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.027317 (rank : 116)
Query Neighborhood Hits	196	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

HES1_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.070084 (rank : 56)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES1_MOUSE
θ value	0.813845 (rank : 71)	NC score	0.070342 (rank : 55)
Query Neighborhood Hits	196	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

SRRM2_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.061856 (rank : 64)
Query Neighborhood Hits	196	Target Neighborhood Hits	1296	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

HUWE1_MOUSE
θ value	1.06291 (rank : 73)	NC score	0.012999 (rank : 146)
Query Neighborhood Hits	196	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

JIP4_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.015158 (rank : 141)
Query Neighborhood Hits	196	Target Neighborhood Hits	585	Shared Neighborhood Hits	22
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

MARK2_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.002476 (rank : 202)
Query Neighborhood Hits	196	Target Neighborhood Hits	1056	Shared Neighborhood Hits	26
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

GAGD3_HUMAN
θ value	1.38821 (rank : 76)	NC score	0.022532 (rank : 128)
Query Neighborhood Hits	196	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GT9, Q5HYR4	Gene names	XAGE2, GAGED3
Domain Architecture
Description	G antigen family D member 3 (Protein XAGE-2).

MAGE1_HUMAN
θ value	1.38821 (rank : 77)	NC score	0.032159 (rank : 104)
Query Neighborhood Hits	196	Target Neighborhood Hits	1389	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

RBM12_HUMAN
θ value	1.38821 (rank : 78)	NC score	0.049777 (rank : 76)
Query Neighborhood Hits	196	Target Neighborhood Hits	298	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

REST_MOUSE
θ value	1.38821 (rank : 79)	NC score	0.012329 (rank : 149)
Query Neighborhood Hits	196	Target Neighborhood Hits	1506	Shared Neighborhood Hits	40
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RGS3_HUMAN
θ value	1.38821 (rank : 80)	NC score	0.026108 (rank : 119)
Query Neighborhood Hits	196	Target Neighborhood Hits	1375	Shared Neighborhood Hits	67
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

YLPM1_MOUSE
θ value	1.38821 (rank : 81)	NC score	0.036496 (rank : 91)
Query Neighborhood Hits	196	Target Neighborhood Hits	505	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

BAZ2A_HUMAN
θ value	1.81305 (rank : 82)	NC score	0.035166 (rank : 95)
Query Neighborhood Hits	196	Target Neighborhood Hits	780	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CECR2_HUMAN
θ value	1.81305 (rank : 83)	NC score	0.040560 (rank : 86)
Query Neighborhood Hits	196	Target Neighborhood Hits	543	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

ENR1_HUMAN
θ value	1.81305 (rank : 84)	NC score	0.031925 (rank : 105)
Query Neighborhood Hits	196	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

HES4_HUMAN
θ value	1.81305 (rank : 85)	NC score	0.072869 (rank : 52)
Query Neighborhood Hits	196	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

IPO4_HUMAN
θ value	1.81305 (rank : 86)	NC score	0.024732 (rank : 123)
Query Neighborhood Hits	196	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

MLX_HUMAN
θ value	1.81305 (rank : 87)	NC score	0.093152 (rank : 48)
Query Neighborhood Hits	196	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
θ value	1.81305 (rank : 88)	NC score	0.093059 (rank : 49)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

PTN23_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.019286 (rank : 132)
Query Neighborhood Hits	196	Target Neighborhood Hits	646	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SEMG2_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.022829 (rank : 127)
Query Neighborhood Hits	196	Target Neighborhood Hits	251	Shared Neighborhood Hits	13
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

SF3A2_MOUSE
θ value	1.81305 (rank : 91)	NC score	0.036612 (rank : 90)
Query Neighborhood Hits	196	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

TNR6A_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.032519 (rank : 103)
Query Neighborhood Hits	196	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

HEY1_HUMAN
θ value	2.36792 (rank : 93)	NC score	0.108427 (rank : 44)
Query Neighborhood Hits	196	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

HEY1_MOUSE
θ value	2.36792 (rank : 94)	NC score	0.111437 (rank : 43)
Query Neighborhood Hits	196	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY2_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.114833 (rank : 41)
Query Neighborhood Hits	196	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.113081 (rank : 42)
Query Neighborhood Hits	196	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HGS_HUMAN
θ value	2.36792 (rank : 97)	NC score	0.036279 (rank : 92)
Query Neighborhood Hits	196	Target Neighborhood Hits	517	Shared Neighborhood Hits	31
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

MYH8_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.009555 (rank : 163)
Query Neighborhood Hits	196	Target Neighborhood Hits	1600	Shared Neighborhood Hits	39
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

PACS1_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.022175 (rank : 129)
Query Neighborhood Hits	196	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SFPQ_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.031629 (rank : 107)
Query Neighborhood Hits	196	Target Neighborhood Hits	986	Shared Neighborhood Hits	45
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

WBP11_HUMAN
θ value	2.36792 (rank : 101)	NC score	0.050265 (rank : 75)
Query Neighborhood Hits	196	Target Neighborhood Hits	354	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.048863 (rank : 78)
Query Neighborhood Hits	196	Target Neighborhood Hits	362	Shared Neighborhood Hits	28
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

BRWD1_MOUSE
θ value	3.0926 (rank : 103)	NC score	0.007729 (rank : 184)
Query Neighborhood Hits	196	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

CAC1G_HUMAN
θ value	3.0926 (rank : 104)	NC score	0.010655 (rank : 157)
Query Neighborhood Hits	196	Target Neighborhood Hits	587	Shared Neighborhood Hits	44
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

MAP1A_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.026079 (rank : 120)
Query Neighborhood Hits	196	Target Neighborhood Hits	1626	Shared Neighborhood Hits	72
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SRRM2_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.058273 (rank : 68)
Query Neighborhood Hits	196	Target Neighborhood Hits	1470	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

ZEP2_MOUSE
θ value	3.0926 (rank : 107)	NC score	0.004771 (rank : 198)
Query Neighborhood Hits	196	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

CEL_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.016397 (rank : 137)
Query Neighborhood Hits	196	Target Neighborhood Hits	896	Shared Neighborhood Hits	53
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

I10R1_MOUSE
θ value	4.03905 (rank : 109)	NC score	0.014593 (rank : 143)
Query Neighborhood Hits	196	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q61727	Gene names	Il10ra, Il10r
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

KBTB3_HUMAN
θ value	4.03905 (rank : 110)	NC score	0.004460 (rank : 199)
Query Neighborhood Hits	196	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAB2, Q86X38, Q96NK5	Gene names	KBTBD3, BKLHD3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KCND2_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.007777 (rank : 182)
Query Neighborhood Hits	196	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

MAST1_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.000465 (rank : 209)
Query Neighborhood Hits	196	Target Neighborhood Hits	1123	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MEIS2_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.012115 (rank : 153)
Query Neighborhood Hits	196	Target Neighborhood Hits	182	Shared Neighborhood Hits	13
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MEIS2_MOUSE
θ value	4.03905 (rank : 114)	NC score	0.012157 (rank : 152)
Query Neighborhood Hits	196	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

PLEC1_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.008318 (rank : 173)
Query Neighborhood Hits	196	Target Neighborhood Hits	1326	Shared Neighborhood Hits	34
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SHAN2_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.016173 (rank : 139)
Query Neighborhood Hits	196	Target Neighborhood Hits	346	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

SON_HUMAN
θ value	4.03905 (rank : 117)	NC score	0.042608 (rank : 84)
Query Neighborhood Hits	196	Target Neighborhood Hits	1568	Shared Neighborhood Hits	91
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

SPRE_MOUSE
θ value	4.03905 (rank : 118)	NC score	0.014858 (rank : 142)
Query Neighborhood Hits	196	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q64105, Q63996	Gene names	Spr
Domain Architecture
Description	Sepiapterin reductase (EC 1.1.1.153) (SPR).

SSBP4_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.036011 (rank : 93)
Query Neighborhood Hits	196	Target Neighborhood Hits	753	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

TCF8_MOUSE
θ value	4.03905 (rank : 120)	NC score	0.000921 (rank : 205)
Query Neighborhood Hits	196	Target Neighborhood Hits	1067	Shared Neighborhood Hits	27
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

UB2E2_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.006539 (rank : 195)
Query Neighborhood Hits	196	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LR5	Gene names	UBE2E2, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) (UbcH8).

UB2E2_MOUSE
θ value	4.03905 (rank : 122)	NC score	0.006637 (rank : 194)
Query Neighborhood Hits	196	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W82	Gene names	Ube2e2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2).

ZIMP7_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.027259 (rank : 117)
Query Neighborhood Hits	196	Target Neighborhood Hits	566	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

ADA17_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.007740 (rank : 183)
Query Neighborhood Hits	196	Target Neighborhood Hits	223	Shared Neighborhood Hits	3
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.007931 (rank : 179)
Query Neighborhood Hits	196	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

CENPE_HUMAN
θ value	5.27518 (rank : 126)	NC score	0.007143 (rank : 188)
Query Neighborhood Hits	196	Target Neighborhood Hits	2060	Shared Neighborhood Hits	45
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

COHA1_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.018860 (rank : 133)
Query Neighborhood Hits	196	Target Neighborhood Hits	414	Shared Neighborhood Hits	27
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CSKI1_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.008808 (rank : 166)
Query Neighborhood Hits	196	Target Neighborhood Hits	997	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DDX21_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.005522 (rank : 197)
Query Neighborhood Hits	196	Target Neighborhood Hits	350	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

EP300_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.047545 (rank : 80)
Query Neighborhood Hits	196	Target Neighborhood Hits	821	Shared Neighborhood Hits	63
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GOGA4_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.008369 (rank : 170)
Query Neighborhood Hits	196	Target Neighborhood Hits	2034	Shared Neighborhood Hits	42
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HIPK1_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.000143 (rank : 210)
Query Neighborhood Hits	196	Target Neighborhood Hits	843	Shared Neighborhood Hits	17
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

M4A12_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.012552 (rank : 147)
Query Neighborhood Hits	196	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXJ0, Q8N6L4	Gene names	MS4A12
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 12.

MLL2_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.034473 (rank : 98)
Query Neighborhood Hits	196	Target Neighborhood Hits	1788	Shared Neighborhood Hits	88
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH13_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.008637 (rank : 168)
Query Neighborhood Hits	196	Target Neighborhood Hits	1504	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH8_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.008303 (rank : 174)
Query Neighborhood Hits	196	Target Neighborhood Hits	1610	Shared Neighborhood Hits	38
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NFAT5_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.022870 (rank : 126)
Query Neighborhood Hits	196	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

PER3_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.152522 (rank : 35)
Query Neighborhood Hits	196	Target Neighborhood Hits	479	Shared Neighborhood Hits	62
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PO6F2_HUMAN
θ value	5.27518 (rank : 139)	NC score	0.025920 (rank : 121)
Query Neighborhood Hits	196	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PO6F2_MOUSE
θ value	5.27518 (rank : 140)	NC score	0.027822 (rank : 115)
Query Neighborhood Hits	196	Target Neighborhood Hits	639	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RFIP3_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.016339 (rank : 138)
Query Neighborhood Hits	196	Target Neighborhood Hits	1055	Shared Neighborhood Hits	47
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SFPQ_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.030619 (rank : 110)
Query Neighborhood Hits	196	Target Neighborhood Hits	958	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

SFR15_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.034759 (rank : 97)
Query Neighborhood Hits	196	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

TROP_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.007076 (rank : 191)
Query Neighborhood Hits	196	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q12816, Q9NU89, Q9UPN8	Gene names	TRO, KIAA1114, MAGED3
Domain Architecture
Description	Trophinin (MAGE-D3 antigen).

ANX11_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.008141 (rank : 176)
Query Neighborhood Hits	196	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

BUB1B_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.008583 (rank : 169)
Query Neighborhood Hits	196	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

C2TA_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.012224 (rank : 151)
Query Neighborhood Hits	196	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

CBL_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.008106 (rank : 177)
Query Neighborhood Hits	196	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CD2L6_HUMAN
θ value	6.88961 (rank : 149)	NC score	-0.001130 (rank : 211)
Query Neighborhood Hits	196	Target Neighborhood Hits	844	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

CR034_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.012460 (rank : 148)
Query Neighborhood Hits	196	Target Neighborhood Hits	643	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CTGE4_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.009040 (rank : 165)
Query Neighborhood Hits	196	Target Neighborhood Hits	393	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

ESX1L_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.010418 (rank : 159)
Query Neighborhood Hits	196	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

F100B_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.016532 (rank : 136)
Query Neighborhood Hits	196	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

GLI3_MOUSE
θ value	6.88961 (rank : 154)	NC score	-0.002137 (rank : 212)
Query Neighborhood Hits	196	Target Neighborhood Hits	807	Shared Neighborhood Hits	13
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.

K0586_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.015778 (rank : 140)
Query Neighborhood Hits	196	Target Neighborhood Hits	311	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

KBTB3_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.003727 (rank : 200)
Query Neighborhood Hits	196	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KCND2_MOUSE
θ value	6.88961 (rank : 157)	NC score	0.007042 (rank : 192)
Query Neighborhood Hits	196	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.007515 (rank : 187)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.007113 (rank : 189)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

LRC46_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.009182 (rank : 164)
Query Neighborhood Hits	196	Target Neighborhood Hits	181	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FV0	Gene names	LRRC46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

MAML3_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.044083 (rank : 82)
Query Neighborhood Hits	196	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MLL3_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.034164 (rank : 100)
Query Neighborhood Hits	196	Target Neighborhood Hits	1644	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MNT_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.028637 (rank : 113)
Query Neighborhood Hits	196	Target Neighborhood Hits	432	Shared Neighborhood Hits	37
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

MRCKG_MOUSE
θ value	6.88961 (rank : 164)	NC score	0.001744 (rank : 204)
Query Neighborhood Hits	196	Target Neighborhood Hits	1466	Shared Neighborhood Hits	34
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MYH3_HUMAN
θ value	6.88961 (rank : 165)	NC score	0.007694 (rank : 186)
Query Neighborhood Hits	196	Target Neighborhood Hits	1660	Shared Neighborhood Hits	34
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_MOUSE
θ value	6.88961 (rank : 166)	NC score	0.008096 (rank : 178)
Query Neighborhood Hits	196	Target Neighborhood Hits	1476	Shared Neighborhood Hits	34
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

NSMA2_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.010228 (rank : 160)
Query Neighborhood Hits	196	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY59	Gene names	SMPD3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

PCDH7_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.000802 (rank : 206)
Query Neighborhood Hits	196	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

PDLI7_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.001834 (rank : 203)
Query Neighborhood Hits	196	Target Neighborhood Hits	279	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PYGO2_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.026207 (rank : 118)
Query Neighborhood Hits	196	Target Neighborhood Hits	189	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

REST_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.008799 (rank : 167)
Query Neighborhood Hits	196	Target Neighborhood Hits	1605	Shared Neighborhood Hits	38
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

RSMB_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.012281 (rank : 150)
Query Neighborhood Hits	196	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

SMC2_HUMAN
θ value	6.88961 (rank : 173)	NC score	0.007862 (rank : 180)
Query Neighborhood Hits	196	Target Neighborhood Hits	1405	Shared Neighborhood Hits	44
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TAF1C_MOUSE
θ value	6.88961 (rank : 174)	NC score	0.029388 (rank : 111)
Query Neighborhood Hits	196	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

AAK1_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.008291 (rank : 175)
Query Neighborhood Hits	196	Target Neighborhood Hits	1077	Shared Neighborhood Hits	38
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ACK1_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.000572 (rank : 208)
Query Neighborhood Hits	196	Target Neighborhood Hits	1140	Shared Neighborhood Hits	38
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ASPP2_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.007106 (rank : 190)
Query Neighborhood Hits	196	Target Neighborhood Hits	1156	Shared Neighborhood Hits	40
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CK035_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.009721 (rank : 161)
Query Neighborhood Hits	196	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	Q0VET5, Q9CW10	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35 homolog.

CPSF6_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.031179 (rank : 109)
Query Neighborhood Hits	196	Target Neighborhood Hits	359	Shared Neighborhood Hits	27
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

CPSF6_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.031531 (rank : 108)
Query Neighborhood Hits	196	Target Neighborhood Hits	356	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CT195_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.009572 (rank : 162)
Query Neighborhood Hits	196	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

ERGI2_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.011796 (rank : 155)
Query Neighborhood Hits	196	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR89, Q3UX13, Q9CWM6, Q9CYA2, Q9D4R1, Q9D8Z9	Gene names	Ergic2
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 2.

FMNL_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.017863 (rank : 134)
Query Neighborhood Hits	196	Target Neighborhood Hits	529	Shared Neighborhood Hits	44
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GLI2_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.002715 (rank : 201)
Query Neighborhood Hits	196	Target Neighborhood Hits	971	Shared Neighborhood Hits	30
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

KCT2_MOUSE
θ value	8.99809 (rank : 185)	NC score	0.011623 (rank : 156)
Query Neighborhood Hits	196	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K201, Q5SVC5, Q922L7, Q9CVN1	Gene names	Kct2
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

MARK2_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.000743 (rank : 207)
Query Neighborhood Hits	196	Target Neighborhood Hits	1018	Shared Neighborhood Hits	32
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MAVS_HUMAN
θ value	8.99809 (rank : 187)	NC score	0.017658 (rank : 135)
Query Neighborhood Hits	196	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

MRIP_MOUSE
θ value	8.99809 (rank : 188)	NC score	0.006988 (rank : 193)
Query Neighborhood Hits	196	Target Neighborhood Hits	569	Shared Neighborhood Hits	22
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MYH1_HUMAN
θ value	8.99809 (rank : 189)	NC score	0.007725 (rank : 185)
Query Neighborhood Hits	196	Target Neighborhood Hits	1478	Shared Neighborhood Hits	32
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PAX3_MOUSE
θ value	8.99809 (rank : 190)	NC score	0.006418 (rank : 196)
Query Neighborhood Hits	196	Target Neighborhood Hits	478	Shared Neighborhood Hits	18
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PHLB1_MOUSE
θ value	8.99809 (rank : 191)	NC score	0.025280 (rank : 122)
Query Neighborhood Hits	196	Target Neighborhood Hits	678	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SC24D_HUMAN
θ value	8.99809 (rank : 192)	NC score	0.021148 (rank : 130)
Query Neighborhood Hits	196	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

SHAN2_MOUSE
θ value	8.99809 (rank : 193)	NC score	0.011943 (rank : 154)
Query Neighborhood Hits	196	Target Neighborhood Hits	446	Shared Neighborhood Hits	18
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

SON_MOUSE
θ value	8.99809 (rank : 194)	NC score	0.035890 (rank : 94)
Query Neighborhood Hits	196	Target Neighborhood Hits	957	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

UBP53_HUMAN
θ value	8.99809 (rank : 195)	NC score	0.010532 (rank : 158)
Query Neighborhood Hits	196	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

WDR33_HUMAN
θ value	8.99809 (rank : 196)	NC score	0.022910 (rank : 125)
Query Neighborhood Hits	196	Target Neighborhood Hits	638	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

ATN1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.051534 (rank : 74)
Query Neighborhood Hits	196	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL9_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.056866 (rank : 71)
Query Neighborhood Hits	196	Target Neighborhood Hits	1008	Shared Neighborhood Hits	77
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

HES5_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.068851 (rank : 57)
Query Neighborhood Hits	196	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

PER1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.143443 (rank : 37)
Query Neighborhood Hits	196	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.147481 (rank : 36)
Query Neighborhood Hits	196	Target Neighborhood Hits	170	Shared Neighborhood Hits	35
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER2_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.139792 (rank : 38)
Query Neighborhood Hits	196	Target Neighborhood Hits	325	Shared Neighborhood Hits	45
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

PER3_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.155402 (rank : 34)
Query Neighborhood Hits	196	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

TCFL5_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.062117 (rank : 63)
Query Neighborhood Hits	196	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

TFE3_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.081043 (rank : 51)
Query Neighborhood Hits	196	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

TFEB_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.070928 (rank : 54)
Query Neighborhood Hits	196	Target Neighborhood Hits	111	Shared Neighborhood Hits	27
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

TFEB_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.071809 (rank : 53)
Query Neighborhood Hits	196	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

USF1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.062903 (rank : 61)
Query Neighborhood Hits	196	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.062873 (rank : 62)
Query Neighborhood Hits	196	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.061002 (rank : 66)
Query Neighborhood Hits	196	Target Neighborhood Hits	155	Shared Neighborhood Hits	25
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

USF2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.057522 (rank : 69)
Query Neighborhood Hits	196	Target Neighborhood Hits	173	Shared Neighborhood Hits	27
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

YLPM1_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.057165 (rank : 70)
Query Neighborhood Hits	196	Target Neighborhood Hits	670	Shared Neighborhood Hits	52
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

Hits sorted by NC score

NCOA1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	196	Target Neighborhood Hits	196	Shared Neighborhood Hits	196
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.986315 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	196	Target Neighborhood Hits	198	Shared Neighborhood Hits	108
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA3_HUMAN
NC score	0.912004 (rank : 3)	θ value	2.36115e-125 (rank : 5)
Query Neighborhood Hits	196	Target Neighborhood Hits	171	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NCOA2_HUMAN
NC score	0.910251 (rank : 4)	θ value	1.7349e-152 (rank : 4)
Query Neighborhood Hits	196	Target Neighborhood Hits	281	Shared Neighborhood Hits	52
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NCOA2_MOUSE
NC score	0.909492 (rank : 5)	θ value	7.78761e-153 (rank : 3)
Query Neighborhood Hits	196	Target Neighborhood Hits	281	Shared Neighborhood Hits	53
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA3_MOUSE
NC score	0.898766 (rank : 6)	θ value	4.61877e-113 (rank : 6)
Query Neighborhood Hits	196	Target Neighborhood Hits	203	Shared Neighborhood Hits	47
SwissProt Accessions	O09000, Q9CRD5	Gene names	Ncoa3, Aib1, Pcip, Rac3, Tram1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein homolog) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP- interacting protein) (p/CIP) (pCIP).

CLOCK_MOUSE
NC score	0.653957 (rank : 7)	θ value	1.38178e-16 (rank : 10)
Query Neighborhood Hits	196	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	O08785	Gene names	Clock
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (mCLOCK).

CLOCK_HUMAN
NC score	0.652972 (rank : 8)	θ value	3.07829e-16 (rank : 12)
Query Neighborhood Hits	196	Target Neighborhood Hits	127	Shared Neighborhood Hits	46
SwissProt Accessions	O15516, O14516, Q9UIT8	Gene names	CLOCK, KIAA0334
Domain Architecture
Description	Circadian locomoter output cycles protein kaput (hCLOCK).

BMAL1_HUMAN
NC score	0.644918 (rank : 9)	θ value	2.35696e-16 (rank : 11)
Query Neighborhood Hits	196	Target Neighborhood Hits	115	Shared Neighborhood Hits	48
SwissProt Accessions	O00327, O00313, O00314, O00315, O00316, O00317, Q99631, Q99649	Gene names	ARNTL, BMAL1, MOP3
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Member of PAS protein 3) (Basic-helix-loop- helix-PAS orphan MOP3) (bHLH-PAS protein JAP3).

SIM1_HUMAN
NC score	0.642206 (rank : 10)	θ value	1.13037e-18 (rank : 7)
Query Neighborhood Hits	196	Target Neighborhood Hits	62	Shared Neighborhood Hits	38
SwissProt Accessions	P81133, Q5TDP7	Gene names	SIM1
Domain Architecture
Description	Single-minded homolog 1.

BMAL1_MOUSE
NC score	0.642078 (rank : 11)	θ value	1.52774e-15 (rank : 16)
Query Neighborhood Hits	196	Target Neighborhood Hits	121	Shared Neighborhood Hits	49
SwissProt Accessions	Q9WTL8, O88295, Q921S4, Q9R0U2, Q9WTL9	Gene names	Arntl, Bmal1
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator-like protein 1 (Brain and muscle ARNT-like 1) (Arnt3).

SIM1_MOUSE
NC score	0.641130 (rank : 12)	θ value	3.28887e-18 (rank : 8)
Query Neighborhood Hits	196	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q61045, O70284, P70183	Gene names	Sim1
Domain Architecture
Description	Single-minded homolog 1 (mSIM1).

SIM2_MOUSE
NC score	0.636165 (rank : 13)	θ value	5.60996e-18 (rank : 9)
Query Neighborhood Hits	196	Target Neighborhood Hits	75	Shared Neighborhood Hits	38
SwissProt Accessions	Q61079, O35391, Q61046, Q61904	Gene names	Sim2
Domain Architecture
Description	Single-minded homolog 2 (SIM transcription factor) (mSIM).

AHR_HUMAN
NC score	0.634284 (rank : 14)	θ value	7.84624e-12 (rank : 26)
Query Neighborhood Hits	196	Target Neighborhood Hits	47	Shared Neighborhood Hits	36
SwissProt Accessions	P35869, Q13728, Q13803, Q13804	Gene names	AHR
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

SIM2_HUMAN
NC score	0.633834 (rank : 15)	θ value	5.25075e-16 (rank : 13)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	40
SwissProt Accessions	Q14190, O60766, Q15470, Q15471, Q15472, Q15473, Q16532	Gene names	SIM2
Domain Architecture
Description	Single-minded homolog 2.

NPAS2_MOUSE
NC score	0.632798 (rank : 16)	θ value	6.85773e-16 (rank : 14)
Query Neighborhood Hits	196	Target Neighborhood Hits	132	Shared Neighborhood Hits	55
SwissProt Accessions	P97460	Gene names	Npas2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2).

NPAS2_HUMAN
NC score	0.628594 (rank : 17)	θ value	8.95645e-16 (rank : 15)
Query Neighborhood Hits	196	Target Neighborhood Hits	150	Shared Neighborhood Hits	51
SwissProt Accessions	Q99743, Q99629	Gene names	NPAS2
Domain Architecture
Description	Neuronal PAS domain-containing protein 2 (Neuronal PAS2) (Member of PAS protein 4) (MOP4).

AHR_MOUSE
NC score	0.625799 (rank : 18)	θ value	6.00763e-12 (rank : 25)
Query Neighborhood Hits	196	Target Neighborhood Hits	55	Shared Neighborhood Hits	33
SwissProt Accessions	P30561, Q8QZX6, Q8R4S3, Q99P79, Q9QVY1	Gene names	Ahr
Domain Architecture
Description	Aryl hydrocarbon receptor precursor (Ah receptor) (AhR).

HIF1A_HUMAN
NC score	0.624412 (rank : 19)	θ value	5.43371e-13 (rank : 21)
Query Neighborhood Hits	196	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

HIF1A_MOUSE
NC score	0.623619 (rank : 20)	θ value	2.69671e-12 (rank : 23)
Query Neighborhood Hits	196	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q61221, O08741, O08993, Q61664, Q61665, Q8C681, Q8CC19, Q8CCB6, Q8R385, Q9CYA8	Gene names	Hif1a
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein).

EPAS1_MOUSE
NC score	0.620193 (rank : 21)	θ value	3.89403e-11 (rank : 29)
Query Neighborhood Hits	196	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

EPAS1_HUMAN
NC score	0.617030 (rank : 22)	θ value	8.67504e-11 (rank : 30)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	Q99814, Q86VA2, Q99630	Gene names	EPAS1, HIF2A
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Member of PAS protein 2) (MOP2) (Hypoxia-inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (HLF).

NPAS1_MOUSE
NC score	0.611396 (rank : 23)	θ value	7.84624e-12 (rank : 27)
Query Neighborhood Hits	196	Target Neighborhood Hits	63	Shared Neighborhood Hits	38
SwissProt Accessions	P97459	Gene names	Npas1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1).

ARNT2_MOUSE
NC score	0.610391 (rank : 24)	θ value	7.58209e-15 (rank : 18)
Query Neighborhood Hits	196	Target Neighborhood Hits	115	Shared Neighborhood Hits	46
SwissProt Accessions	Q61324	Gene names	Arnt2
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

ARNT2_HUMAN
NC score	0.610070 (rank : 25)	θ value	7.58209e-15 (rank : 17)
Query Neighborhood Hits	196	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HBZ2, O15024	Gene names	ARNT2, KIAA0307
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator 2 (ARNT protein 2).

NPAS1_HUMAN
NC score	0.603229 (rank : 26)	θ value	1.33837e-11 (rank : 28)
Query Neighborhood Hits	196	Target Neighborhood Hits	77	Shared Neighborhood Hits	37
SwissProt Accessions	Q99742, Q99632, Q9BY83	Gene names	NPAS1
Domain Architecture
Description	Neuronal PAS domain-containing protein 1 (Neuronal PAS1) (Member of PAS protein 5) (MOP5).

NPAS3_MOUSE
NC score	0.601608 (rank : 27)	θ value	2.0648e-12 (rank : 22)
Query Neighborhood Hits	196	Target Neighborhood Hits	103	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QZQ0, Q9EQP4	Gene names	Npas3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

ARNT_HUMAN
NC score	0.599347 (rank : 28)	θ value	1.42992e-13 (rank : 19)
Query Neighborhood Hits	196	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	P27540	Gene names	ARNT
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS3_HUMAN
NC score	0.598693 (rank : 29)	θ value	2.69671e-12 (rank : 24)
Query Neighborhood Hits	196	Target Neighborhood Hits	81	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IXF0, Q86US6, Q86US7, Q8IXF2, Q9BY81, Q9H323, Q9Y4L8	Gene names	NPAS3
Domain Architecture
Description	Neuronal PAS domain-containing protein 3 (Neuronal PAS3) (Member of PAS protein 6) (MOP6).

ARNT_MOUSE
NC score	0.590805 (rank : 30)	θ value	2.43908e-13 (rank : 20)
Query Neighborhood Hits	196	Target Neighborhood Hits	213	Shared Neighborhood Hits	58
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

NPAS4_HUMAN
NC score	0.418035 (rank : 31)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	196	Target Neighborhood Hits	214	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
NC score	0.410035 (rank : 32)	θ value	0.00175202 (rank : 32)
Query Neighborhood Hits	196	Target Neighborhood Hits	245	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

PER1_HUMAN
NC score	0.161444 (rank : 33)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	196	Target Neighborhood Hits	215	Shared Neighborhood Hits	40
SwissProt Accessions	O15534	Gene names	PER1, KIAA0482, PER, RIGUI
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (hPER).

PER3_MOUSE
NC score	0.155402 (rank : 34)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	196	Target Neighborhood Hits	85	Shared Neighborhood Hits	23
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PER3_HUMAN
NC score	0.152522 (rank : 35)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	196	Target Neighborhood Hits	479	Shared Neighborhood Hits	62
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

PER2_HUMAN
NC score	0.147481 (rank : 36)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	196	Target Neighborhood Hits	170	Shared Neighborhood Hits	35
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PER1_MOUSE
NC score	0.143443 (rank : 37)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	196	Target Neighborhood Hits	235	Shared Neighborhood Hits	40
SwissProt Accessions	O35973	Gene names	Per1, Per, Rigui
Domain Architecture
Description	Period circadian protein 1 (Circadian pacemaker protein Rigui) (mPER) (M-Rigui).

PER2_MOUSE
NC score	0.139792 (rank : 38)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	196	Target Neighborhood Hits	325	Shared Neighborhood Hits	45
SwissProt Accessions	O54943, O54954	Gene names	Per2
Domain Architecture
Description	Period circadian protein 2 (mPER2).

NCOA6_MOUSE
NC score	0.125737 (rank : 39)	θ value	0.00509761 (rank : 34)
Query Neighborhood Hits	196	Target Neighborhood Hits	1076	Shared Neighborhood Hits	77
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

NCOA6_HUMAN
NC score	0.125210 (rank : 40)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	196	Target Neighborhood Hits	1202	Shared Neighborhood Hits	83
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

HEY2_HUMAN
NC score	0.114833 (rank : 41)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	196	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBP5	Gene names	HEY2, CHF1, GRL, HERP, HERP1, HRT2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Cardiovascular helix-loop-helix factor 1) (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES- related repressor protein 2) (Protein gridlock homolog).

HEY2_MOUSE
NC score	0.113081 (rank : 42)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	196	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	Q9QUS4, Q3TZ99, Q8CD44	Gene names	Hey2, Chf1, Herp, Herp1, Hesr2, Hrt2
Domain Architecture	No domain graphic available
Description	Hairy/enhancer-of-split related with YRPW motif 2 (Hairy and enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription factor 2) (HES-related repressor protein 2).

HEY1_MOUSE
NC score	0.111437 (rank : 43)	θ value	2.36792 (rank : 94)
Query Neighborhood Hits	196	Target Neighborhood Hits	69	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WV93	Gene names	Hey1, Hesr1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1).

HEY1_HUMAN
NC score	0.108427 (rank : 44)	θ value	2.36792 (rank : 93)
Query Neighborhood Hits	196	Target Neighborhood Hits	82	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5J3, Q5TZS3, Q9NYP4	Gene names	HEY1, CHF2, HESR1
Domain Architecture
Description	Hairy/enhancer-of-split related with YRPW motif 1 (Hairy and enhancer of split-related protein 1) (HESR-1) (Cardiovascular helix-loop-helix factor 2) (HES-related repressor protein 2) (HERP2).

MITF_MOUSE
NC score	0.101094 (rank : 45)	θ value	0.62314 (rank : 66)
Query Neighborhood Hits	196	Target Neighborhood Hits	115	Shared Neighborhood Hits	32
SwissProt Accessions	Q08874, O08885, O88203, Q08843, Q60781, Q60782, Q9JIJ0, Q9JIJ1, Q9JIJ2, Q9JIJ3, Q9JIJ4, Q9JIJ5, Q9JIJ6, Q9JKX9	Gene names	Mitf, Bw, Mi, Vit
Domain Architecture
Description	Microphthalmia-associated transcription factor.

MITF_HUMAN
NC score	0.099038 (rank : 46)	θ value	0.62314 (rank : 65)
Query Neighborhood Hits	196	Target Neighborhood Hits	113	Shared Neighborhood Hits	30
SwissProt Accessions	O75030, Q14841, Q9P2V0, Q9P2V1, Q9P2V2, Q9P2Y8	Gene names	MITF
Domain Architecture
Description	Microphthalmia-associated transcription factor.

HES7_HUMAN
NC score	0.096433 (rank : 47)	θ value	0.62314 (rank : 63)
Query Neighborhood Hits	196	Target Neighborhood Hits	72	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYE0	Gene names	HES7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

MLX_HUMAN
NC score	0.093152 (rank : 48)	θ value	1.81305 (rank : 87)
Query Neighborhood Hits	196	Target Neighborhood Hits	95	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UH92, Q53XM6, Q96FL2, Q9H2V0, Q9H2V1, Q9H2V2, Q9NXN3	Gene names	MLX, TCFL4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

MLX_MOUSE
NC score	0.093059 (rank : 49)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	196	Target Neighborhood Hits	100	Shared Neighborhood Hits	24
SwissProt Accessions	O08609, Q9EQJ7, Q9EQJ8	Gene names	Mlx, Tcfl4
Domain Architecture
Description	Max-like protein X (Max-like bHLHZip protein) (BigMax protein) (Protein Mlx) (Transcription factor-like protein 4).

HES7_MOUSE
NC score	0.092669 (rank : 50)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	196	Target Neighborhood Hits	72	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BKT2, Q99JA6	Gene names	Hes7
Domain Architecture	No domain graphic available
Description	Transcription factor HES-7 (Hairy and enhancer of split 7) (bHLH factor Hes7).

TFE3_HUMAN
NC score	0.081043 (rank : 51)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	196	Target Neighborhood Hits	190	Shared Neighborhood Hits	36
SwissProt Accessions	P19532, Q92757, Q92758, Q99964	Gene names	TFE3
Domain Architecture
Description	Transcription factor E3.

HES4_HUMAN
NC score	0.072869 (rank : 52)	θ value	1.81305 (rank : 85)
Query Neighborhood Hits	196	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCC6	Gene names	HES4
Domain Architecture
Description	Transcription factor HES-4 (Hairy and enhancer of split 4) (bHLH factor Hes4).

TFEB_MOUSE
NC score	0.071809 (rank : 53)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	196	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R210	Gene names	Tfeb, Tcfeb
Domain Architecture
Description	Transcription factor EB.

TFEB_HUMAN
NC score	0.070928 (rank : 54)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	196	Target Neighborhood Hits	111	Shared Neighborhood Hits	27
SwissProt Accessions	P19484, Q709B3, Q7Z6P9, Q9BRJ5, Q9UJD8	Gene names	TFEB
Domain Architecture
Description	Transcription factor EB.

HES1_MOUSE
NC score	0.070342 (rank : 55)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	196	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P35428	Gene names	Hes1, Hes-1
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1).

HES1_HUMAN
NC score	0.070084 (rank : 56)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	196	Target Neighborhood Hits	76	Shared Neighborhood Hits	21
SwissProt Accessions	Q14469	Gene names	HES1, HL, HRY
Domain Architecture
Description	Transcription factor HES-1 (Hairy and enhancer of split 1) (Hairy- like) (HHL) (Hairy homolog).

HES5_MOUSE
NC score	0.068851 (rank : 57)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	196	Target Neighborhood Hits	38	Shared Neighborhood Hits	22
SwissProt Accessions	P70120, Q8BVI1	Gene names	Hes5, Hes-5
Domain Architecture
Description	Transcription factor HES-5 (Hairy and enhancer of split 5).

RU1C_HUMAN
NC score	0.068777 (rank : 58)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	196	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	P09234	Gene names	SNRPC
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

RU1C_MOUSE
NC score	0.068187 (rank : 59)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	196	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q62241	Gene names	Snrp1c, Snrpc
Domain Architecture
Description	U1 small nuclear ribonucleoprotein C (U1 snRNP protein C) (U1C protein) (U1-C).

PRP2_MOUSE
NC score	0.063958 (rank : 60)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	196	Target Neighborhood Hits	347	Shared Neighborhood Hits	29
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

USF1_HUMAN
NC score	0.062903 (rank : 61)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	196	Target Neighborhood Hits	70	Shared Neighborhood Hits	20
SwissProt Accessions	P22415	Gene names	USF1, USF
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

USF1_MOUSE
NC score	0.062873 (rank : 62)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	196	Target Neighborhood Hits	71	Shared Neighborhood Hits	20
SwissProt Accessions	Q61069	Gene names	Usf1, Usf
Domain Architecture
Description	Upstream stimulatory factor 1 (Major late transcription factor 1).

TCFL5_HUMAN
NC score	0.062117 (rank : 63)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	196	Target Neighborhood Hits	43	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UL49, O94771, Q9BYW0	Gene names	TCFL5, CHA, E2BP1
Domain Architecture	No domain graphic available
Description	Transcription factor-like 5 protein (Cha transcription factor) (HPV-16 E2-binding protein 1) (E2BP-1).

SRRM2_HUMAN
NC score	0.061856 (rank : 64)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	196	Target Neighborhood Hits	1296	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

AF9_HUMAN
NC score	0.061444 (rank : 65)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	196	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

USF2_HUMAN
NC score	0.061002 (rank : 66)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	196	Target Neighborhood Hits	155	Shared Neighborhood Hits	25
SwissProt Accessions	Q15853, O00671, O00709, Q05750, Q07952, Q15851, Q15852	Gene names	USF2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (FOS- interacting protein) (FIP) (Major late transcription factor 2).

DSPP_HUMAN
NC score	0.058500 (rank : 67)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	196	Target Neighborhood Hits	645	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

SRRM2_MOUSE
NC score	0.058273 (rank : 68)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	196	Target Neighborhood Hits	1470	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

USF2_MOUSE
NC score	0.057522 (rank : 69)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	196	Target Neighborhood Hits	173	Shared Neighborhood Hits	27
SwissProt Accessions	Q64705, Q3UIL2, Q8VE59	Gene names	Usf2
Domain Architecture
Description	Upstream stimulatory factor 2 (Upstream transcription factor 2) (Major late transcription factor 2).

YLPM1_HUMAN
NC score	0.057165 (rank : 70)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	196	Target Neighborhood Hits	670	Shared Neighborhood Hits	52
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BCL9_HUMAN
NC score	0.056866 (rank : 71)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	196	Target Neighborhood Hits	1008	Shared Neighborhood Hits	77
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

RBM12_MOUSE
NC score	0.053389 (rank : 72)	θ value	0.365318 (rank : 51)
Query Neighborhood Hits	196	Target Neighborhood Hits	313	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

PCLO_MOUSE
NC score	0.052985 (rank : 73)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	196	Target Neighborhood Hits	2275	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

ATN1_HUMAN
NC score	0.051534 (rank : 74)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	196	Target Neighborhood Hits	676	Shared Neighborhood Hits	56
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

WBP11_HUMAN
NC score	0.050265 (rank : 75)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	196	Target Neighborhood Hits	354	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

RBM12_HUMAN
NC score	0.049777 (rank : 76)	θ value	1.38821 (rank : 78)
Query Neighborhood Hits	196	Target Neighborhood Hits	298	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

LSM11_HUMAN
NC score	0.049652 (rank : 77)	θ value	0.0736092 (rank : 36)
Query Neighborhood Hits	196	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P83369, Q7Z7P0, Q8N975	Gene names	LSM11
Domain Architecture	No domain graphic available
Description	U7 snRNA-associated Sm-like protein LSm11.

WBP11_MOUSE
NC score	0.048863 (rank : 78)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	196	Target Neighborhood Hits	362	Shared Neighborhood Hits	28
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

PELP1_HUMAN
NC score	0.048471 (rank : 79)	θ value	0.47712 (rank : 56)
Query Neighborhood Hits	196	Target Neighborhood Hits	596	Shared Neighborhood Hits	36
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

EP300_HUMAN
NC score	0.047545 (rank : 80)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	196	Target Neighborhood Hits	821	Shared Neighborhood Hits	63
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

RCOR3_MOUSE
NC score	0.045631 (rank : 81)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	196	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PGA0	Gene names	Rcor3
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

MAML3_HUMAN
NC score	0.044083 (rank : 82)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	196	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

RBBP6_MOUSE
NC score	0.043536 (rank : 83)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	196	Target Neighborhood Hits	1014	Shared Neighborhood Hits	43
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

SON_HUMAN
NC score	0.042608 (rank : 84)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	196	Target Neighborhood Hits	1568	Shared Neighborhood Hits	91
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

NACAM_MOUSE
NC score	0.042245 (rank : 85)	θ value	0.0563607 (rank : 35)
Query Neighborhood Hits	196	Target Neighborhood Hits	1866	Shared Neighborhood Hits	83
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

CECR2_HUMAN
NC score	0.040560 (rank : 86)	θ value	1.81305 (rank : 83)
Query Neighborhood Hits	196	Target Neighborhood Hits	543	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

GGN_MOUSE
NC score	0.040234 (rank : 87)	θ value	0.365318 (rank : 50)
Query Neighborhood Hits	196	Target Neighborhood Hits	311	Shared Neighborhood Hits	25
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

DSPP_MOUSE
NC score	0.039804 (rank : 88)	θ value	0.62314 (rank : 62)
Query Neighborhood Hits	196	Target Neighborhood Hits	491	Shared Neighborhood Hits	24
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

BPTF_HUMAN
NC score	0.036673 (rank : 89)	θ value	0.62314 (rank : 61)
Query Neighborhood Hits	196	Target Neighborhood Hits	786	Shared Neighborhood Hits	48
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SF3A2_MOUSE
NC score	0.036612 (rank : 90)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	196	Target Neighborhood Hits	247	Shared Neighborhood Hits	22
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

YLPM1_MOUSE
NC score	0.036496 (rank : 91)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	196	Target Neighborhood Hits	505	Shared Neighborhood Hits	40
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

HGS_HUMAN
NC score	0.036279 (rank : 92)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	196	Target Neighborhood Hits	517	Shared Neighborhood Hits	31
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

SSBP4_HUMAN
NC score	0.036011 (rank : 93)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	196	Target Neighborhood Hits	753	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BWG4	Gene names	SSBP4
Domain Architecture
Description	Single-stranded DNA-binding protein 4.

SON_MOUSE
NC score	0.035890 (rank : 94)	θ value	8.99809 (rank : 194)
Query Neighborhood Hits	196	Target Neighborhood Hits	957	Shared Neighborhood Hits	61
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BAZ2A_HUMAN
NC score	0.035166 (rank : 95)	θ value	1.81305 (rank : 82)
Query Neighborhood Hits	196	Target Neighborhood Hits	780	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

RCOR3_HUMAN
NC score	0.035108 (rank : 96)	θ value	0.47712 (rank : 58)
Query Neighborhood Hits	196	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

SFR15_HUMAN
NC score	0.034759 (rank : 97)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	196	Target Neighborhood Hits	368	Shared Neighborhood Hits	30
SwissProt Accessions	O95104, Q6P1M5, Q8N3I8, Q9UFM1, Q9ULP8	Gene names	SFRS15, KIAA1172
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 15 (CTD-binding SR-like protein RA4).

MLL2_HUMAN
NC score	0.034473 (rank : 98)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	196	Target Neighborhood Hits	1788	Shared Neighborhood Hits	88
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHLB1_HUMAN
NC score	0.034204 (rank : 99)	θ value	0.47712 (rank : 57)
Query Neighborhood Hits	196	Target Neighborhood Hits	1038	Shared Neighborhood Hits	62
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

MLL3_HUMAN
NC score	0.034164 (rank : 100)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	196	Target Neighborhood Hits	1644	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RNPS1_HUMAN
NC score	0.033465 (rank : 101)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	196	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q15287, O75308, Q8WY42, Q9NYG3	Gene names	RNPS1, LDC2
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2).

RNPS1_MOUSE
NC score	0.033465 (rank : 102)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	196	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q99M28, Q3TMJ1, Q922H8	Gene names	Rnps1
Domain Architecture	No domain graphic available
Description	RNA-binding protein with serine-rich domain 1.

TNR6A_HUMAN
NC score	0.032519 (rank : 103)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	196	Target Neighborhood Hits	343	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

MAGE1_HUMAN
NC score	0.032159 (rank : 104)	θ value	1.38821 (rank : 77)
Query Neighborhood Hits	196	Target Neighborhood Hits	1389	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

ENR1_HUMAN
NC score	0.031925 (rank : 105)	θ value	1.81305 (rank : 84)
Query Neighborhood Hits	196	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q14264	Gene names	ERV3
Domain Architecture	No domain graphic available
Description	HERV-R_7q21.2 provirus ancestral Env polyprotein precursor (Envelope polyprotein) (ERV3 envelope protein) (ERV-3 envelope protein) (HERV-R envelope protein) (ERV-R envelope protein) [Contains: Surface protein (SU); Transmembrane protein (TM)].

AFAD_HUMAN
NC score	0.031818 (rank : 106)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	196	Target Neighborhood Hits	689	Shared Neighborhood Hits	29
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

SFPQ_HUMAN
NC score	0.031629 (rank : 107)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	196	Target Neighborhood Hits	986	Shared Neighborhood Hits	45
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

CPSF6_MOUSE
NC score	0.031531 (rank : 108)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	196	Target Neighborhood Hits	356	Shared Neighborhood Hits	27
SwissProt Accessions	Q6NVF9, Q8BX86, Q8BXI8	Gene names	Cpsf6
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6.

CPSF6_HUMAN
NC score	0.031179 (rank : 109)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	196	Target Neighborhood Hits	359	Shared Neighborhood Hits	27
SwissProt Accessions	Q16630, Q53ES1, Q9BSJ7, Q9BW18	Gene names	CPSF6, CFIM68
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII- 4/7).

SFPQ_MOUSE
NC score	0.030619 (rank : 110)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	196	Target Neighborhood Hits	958	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

TAF1C_MOUSE
NC score	0.029388 (rank : 111)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	196	Target Neighborhood Hits	54	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

AN32E_HUMAN
NC score	0.029017 (rank : 112)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	196	Target Neighborhood Hits	291	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

MNT_MOUSE
NC score	0.028637 (rank : 113)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	196	Target Neighborhood Hits	432	Shared Neighborhood Hits	37
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SFRS4_MOUSE
NC score	0.028375 (rank : 114)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	196	Target Neighborhood Hits	406	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VE97, Q9JJC3	Gene names	Sfrs4
Domain Architecture
Description	Splicing factor, arginine/serine-rich 4.

PO6F2_MOUSE
NC score	0.027822 (rank : 115)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	196	Target Neighborhood Hits	639	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

AN32E_MOUSE
NC score	0.027317 (rank : 116)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	196	Target Neighborhood Hits	257	Shared Neighborhood Hits	6
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

ZIMP7_MOUSE
NC score	0.027259 (rank : 117)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	196	Target Neighborhood Hits	566	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CIE2, Q6P558, Q6P9Q5, Q8BJ00	Gene names	Zimp7, D11Bwg0280e
Domain Architecture	No domain graphic available
Description	PIAS-like protein Zimp7.

PYGO2_HUMAN
NC score	0.026207 (rank : 118)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	196	Target Neighborhood Hits	189	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RGS3_HUMAN
NC score	0.026108 (rank : 119)	θ value	1.38821 (rank : 80)
Query Neighborhood Hits	196	Target Neighborhood Hits	1375	Shared Neighborhood Hits	67
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

MAP1A_HUMAN
NC score	0.026079 (rank : 120)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	196	Target Neighborhood Hits	1626	Shared Neighborhood Hits	72
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PO6F2_HUMAN
NC score	0.025920 (rank : 121)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	196	Target Neighborhood Hits	618	Shared Neighborhood Hits	38
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PHLB1_MOUSE
NC score	0.025280 (rank : 122)	θ value	8.99809 (rank : 191)
Query Neighborhood Hits	196	Target Neighborhood Hits	678	Shared Neighborhood Hits	38
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

IPO4_HUMAN
NC score	0.024732 (rank : 123)	θ value	1.81305 (rank : 86)
Query Neighborhood Hits	196	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

UTX_HUMAN
NC score	0.024442 (rank : 124)	θ value	0.47712 (rank : 59)
Query Neighborhood Hits	196	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

WDR33_HUMAN
NC score	0.022910 (rank : 125)	θ value	8.99809 (rank : 196)
Query Neighborhood Hits	196	Target Neighborhood Hits	638	Shared Neighborhood Hits	31
SwissProt Accessions	Q9C0J8	Gene names	WDR33, WDC146
Domain Architecture
Description	WD repeat protein 33 (WD repeat protein WDC146).

NFAT5_HUMAN
NC score	0.022870 (rank : 126)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	196	Target Neighborhood Hits	217	Shared Neighborhood Hits	23
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

SEMG2_HUMAN
NC score	0.022829 (rank : 127)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	196	Target Neighborhood Hits	251	Shared Neighborhood Hits	13
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

GAGD3_HUMAN
NC score	0.022532 (rank : 128)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	196	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q96GT9, Q5HYR4	Gene names	XAGE2, GAGED3
Domain Architecture
Description	G antigen family D member 3 (Protein XAGE-2).

PACS1_MOUSE
NC score	0.022175 (rank : 129)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	196	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SC24D_HUMAN
NC score	0.021148 (rank : 130)	θ value	8.99809 (rank : 192)
Query Neighborhood Hits	196	Target Neighborhood Hits	173	Shared Neighborhood Hits	23
SwissProt Accessions	O94855	Gene names	SEC24D, KIAA0755
Domain Architecture
Description	Protein transport protein Sec24D (SEC24-related protein D).

B4GT1_MOUSE
NC score	0.020468 (rank : 131)	θ value	0.47712 (rank : 54)
Query Neighborhood Hits	196	Target Neighborhood Hits	50	Shared Neighborhood Hits	3
SwissProt Accessions	P15535	Gene names	B4galt1, Ggtb, Ggtb2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

PTN23_HUMAN
NC score	0.019286 (rank : 132)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	196	Target Neighborhood Hits	646	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

COHA1_MOUSE
NC score	0.018860 (rank : 133)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	196	Target Neighborhood Hits	414	Shared Neighborhood Hits	27
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FMNL_HUMAN
NC score	0.017863 (rank : 134)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	196	Target Neighborhood Hits	529	Shared Neighborhood Hits	44
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

MAVS_HUMAN
NC score	0.017658 (rank : 135)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	196	Target Neighborhood Hits	271	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z434, Q3I0Y2, Q5T7I6, Q86VY7, Q9H1H3, Q9H4Y1, Q9H8D3, Q9ULE9	Gene names	MAVS, IPS1, KIAA1271, VISA
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif) (Putative NF-kappa-B- activating protein 031N).

F100B_MOUSE
NC score	0.016532 (rank : 136)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	196	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BQH4, Q3UMH5	Gene names	Fam100b
Domain Architecture	No domain graphic available
Description	Protein FAM100B.

CEL_HUMAN
NC score	0.016397 (rank : 137)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	196	Target Neighborhood Hits	896	Shared Neighborhood Hits	53
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

RFIP3_HUMAN
NC score	0.016339 (rank : 138)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	196	Target Neighborhood Hits	1055	Shared Neighborhood Hits	47
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

SHAN2_HUMAN
NC score	0.016173 (rank : 139)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	196	Target Neighborhood Hits	346	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

K0586_HUMAN
NC score	0.015778 (rank : 140)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	196	Target Neighborhood Hits	311	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

JIP4_HUMAN
NC score	0.015158 (rank : 141)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	196	Target Neighborhood Hits	585	Shared Neighborhood Hits	22
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

SPRE_MOUSE
NC score	0.014858 (rank : 142)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	196	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q64105, Q63996	Gene names	Spr
Domain Architecture
Description	Sepiapterin reductase (EC 1.1.1.153) (SPR).

I10R1_MOUSE
NC score	0.014593 (rank : 143)	θ value	4.03905 (rank : 109)
Query Neighborhood Hits	196	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q61727	Gene names	Il10ra, Il10r
Domain Architecture	No domain graphic available
Description	Interleukin-10 receptor alpha chain precursor (IL-10R-A) (IL-10R1) (CDw210a antigen).

ZEP1_HUMAN
NC score	0.014007 (rank : 144)	θ value	0.62314 (rank : 67)
Query Neighborhood Hits	196	Target Neighborhood Hits	1036	Shared Neighborhood Hits	38
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

PAX3_HUMAN
NC score	0.013977 (rank : 145)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	196	Target Neighborhood Hits	513	Shared Neighborhood Hits	21
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

HUWE1_MOUSE
NC score	0.012999 (rank : 146)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	196	Target Neighborhood Hits	406	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TMY8, Q4G2Z1, Q5BMM7, Q6NS61, Q8BNJ7, Q8CFH2, Q8VD14, Q921M5, Q9R0P2	Gene names	Huwe1, Kiaa0312, Ureb1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (E3Histone).

M4A12_HUMAN
NC score	0.012552 (rank : 147)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	196	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXJ0, Q8N6L4	Gene names	MS4A12
Domain Architecture
Description	Membrane-spanning 4-domains subfamily A member 12.

CR034_MOUSE
NC score	0.012460 (rank : 148)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	196	Target Neighborhood Hits	643	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

REST_MOUSE
NC score	0.012329 (rank : 149)	θ value	1.38821 (rank : 79)
Query Neighborhood Hits	196	Target Neighborhood Hits	1506	Shared Neighborhood Hits	40
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RSMB_HUMAN
NC score	0.012281 (rank : 150)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	196	Target Neighborhood Hits	117	Shared Neighborhood Hits	15
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

C2TA_HUMAN
NC score	0.012224 (rank : 151)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	196	Target Neighborhood Hits	190	Shared Neighborhood Hits	17
SwissProt Accessions	P33076	Gene names	CIITA, MHC2TA
Domain Architecture
Description	MHC class II transactivator (CIITA).

MEIS2_MOUSE
NC score	0.012157 (rank : 152)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	196	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	P97367, O35676, O35677, P97403, P97404	Gene names	Meis2, Mrg1, Stra10
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

MEIS2_HUMAN
NC score	0.012115 (rank : 153)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	196	Target Neighborhood Hits	182	Shared Neighborhood Hits	13
SwissProt Accessions	O14770, Q96KI4, Q96KI5, Q9NRS1, Q9NRS2, Q9NRS3	Gene names	MEIS2, MRG1
Domain Architecture
Description	Homeobox protein Meis2 (Meis1-related protein 1).

SHAN2_MOUSE
NC score	0.011943 (rank : 154)	θ value	8.99809 (rank : 193)
Query Neighborhood Hits	196	Target Neighborhood Hits	446	Shared Neighborhood Hits	18
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

ERGI2_MOUSE
NC score	0.011796 (rank : 155)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	196	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR89, Q3UX13, Q9CWM6, Q9CYA2, Q9D4R1, Q9D8Z9	Gene names	Ergic2
Domain Architecture	No domain graphic available
Description	Endoplasmic reticulum-Golgi intermediate compartment protein 2.

KCT2_MOUSE
NC score	0.011623 (rank : 156)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	196	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K201, Q5SVC5, Q922L7, Q9CVN1	Gene names	Kct2
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

CAC1G_HUMAN
NC score	0.010655 (rank : 157)	θ value	3.0926 (rank : 104)
Query Neighborhood Hits	196	Target Neighborhood Hits	587	Shared Neighborhood Hits	44
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

UBP53_HUMAN
NC score	0.010532 (rank : 158)	θ value	8.99809 (rank : 195)
Query Neighborhood Hits	196	Target Neighborhood Hits	71	Shared Neighborhood Hits	5
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

ESX1L_HUMAN
NC score	0.010418 (rank : 159)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	196	Target Neighborhood Hits	498	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

NSMA2_HUMAN
NC score	0.010228 (rank : 160)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	196	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NY59	Gene names	SMPD3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

CK035_MOUSE
NC score	0.009721 (rank : 161)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	196	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	Q0VET5, Q9CW10	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf35 homolog.

CT195_MOUSE
NC score	0.009572 (rank : 162)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	196	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

MYH8_MOUSE
NC score	0.009555 (rank : 163)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	196	Target Neighborhood Hits	1600	Shared Neighborhood Hits	39
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

LRC46_HUMAN
NC score	0.009182 (rank : 164)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	196	Target Neighborhood Hits	181	Shared Neighborhood Hits	6
SwissProt Accessions	Q96FV0	Gene names	LRRC46
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 46.

CTGE4_HUMAN
NC score	0.009040 (rank : 165)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	196	Target Neighborhood Hits	393	Shared Neighborhood Hits	22
SwissProt Accessions	Q8IX94, O95046	Gene names	CTAGE4
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 4 (cTAGE-4 protein).

CSKI1_HUMAN
NC score	0.008808 (rank : 166)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	196	Target Neighborhood Hits	997	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

REST_HUMAN
NC score	0.008799 (rank : 167)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	196	Target Neighborhood Hits	1605	Shared Neighborhood Hits	38
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MYH13_HUMAN
NC score	0.008637 (rank : 168)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	196	Target Neighborhood Hits	1504	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

BUB1B_MOUSE
NC score	0.008583 (rank : 169)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	196	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

GOGA4_HUMAN
NC score	0.008369 (rank : 170)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	196	Target Neighborhood Hits	2034	Shared Neighborhood Hits	42
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

FOG2_HUMAN
NC score	0.008344 (rank : 171)	θ value	0.47712 (rank : 55)
Query Neighborhood Hits	196	Target Neighborhood Hits	731	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WW38, Q9NPL7, Q9NPS4, Q9UNI5	Gene names	ZFPM2, FOG2
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM2 (Zinc finger protein multitype 2) (Friend of GATA protein 2) (FOG-2) (hFOG-2).

WNK2_HUMAN
NC score	0.008330 (rank : 172)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	196	Target Neighborhood Hits	1407	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PLEC1_HUMAN
NC score	0.008318 (rank : 173)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	196	Target Neighborhood Hits	1326	Shared Neighborhood Hits	34
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MYH8_HUMAN
NC score	0.008303 (rank : 174)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	196	Target Neighborhood Hits	1610	Shared Neighborhood Hits	38
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

AAK1_HUMAN
NC score	0.008291 (rank : 175)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	196	Target Neighborhood Hits	1077	Shared Neighborhood Hits	38
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ANX11_HUMAN
NC score	0.008141 (rank : 176)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	196	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	P50995	Gene names	ANXA11, ANX11
Domain Architecture
Description	Annexin A11 (Annexin XI) (Calcyclin-associated annexin 50) (CAP-50) (56 kDa autoantigen).

CBL_HUMAN
NC score	0.008106 (rank : 177)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	196	Target Neighborhood Hits	353	Shared Neighborhood Hits	18
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

MYH4_MOUSE
NC score	0.008096 (rank : 178)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	196	Target Neighborhood Hits	1476	Shared Neighborhood Hits	34
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

ADA17_MOUSE
NC score	0.007931 (rank : 179)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	196	Target Neighborhood Hits	201	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

SMC2_HUMAN
NC score	0.007862 (rank : 180)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	196	Target Neighborhood Hits	1405	Shared Neighborhood Hits	44
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TRIO_HUMAN
NC score	0.007779 (rank : 181)	θ value	0.0961366 (rank : 37)
Query Neighborhood Hits	196	Target Neighborhood Hits	1580	Shared Neighborhood Hits	37
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

KCND2_HUMAN
NC score	0.007777 (rank : 182)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	196	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

ADA17_HUMAN
NC score	0.007740 (rank : 183)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	196	Target Neighborhood Hits	223	Shared Neighborhood Hits	3
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

BRWD1_MOUSE
NC score	0.007729 (rank : 184)	θ value	3.0926 (rank : 103)
Query Neighborhood Hits	196	Target Neighborhood Hits	478	Shared Neighborhood Hits	10
SwissProt Accessions	Q921C3, Q921C2	Gene names	Brwd1, Wdr9
Domain Architecture	No domain graphic available
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

MYH1_HUMAN
NC score	0.007725 (rank : 185)	θ value	8.99809 (rank : 189)
Query Neighborhood Hits	196	Target Neighborhood Hits	1478	Shared Neighborhood Hits	32
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH3_HUMAN
NC score	0.007694 (rank : 186)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	196	Target Neighborhood Hits	1660	Shared Neighborhood Hits	34
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

KCND3_HUMAN
NC score	0.007515 (rank : 187)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

CENPE_HUMAN
NC score	0.007143 (rank : 188)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	196	Target Neighborhood Hits	2060	Shared Neighborhood Hits	45
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

KCND3_MOUSE
NC score	0.007113 (rank : 189)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	196	Target Neighborhood Hits	162	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

ASPP2_HUMAN
NC score	0.007106 (rank : 190)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	196	Target Neighborhood Hits	1156	Shared Neighborhood Hits	40
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

TROP_HUMAN
NC score	0.007076 (rank : 191)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	196	Target Neighborhood Hits	158	Shared Neighborhood Hits	9
SwissProt Accessions	Q12816, Q9NU89, Q9UPN8	Gene names	TRO, KIAA1114, MAGED3
Domain Architecture
Description	Trophinin (MAGE-D3 antigen).

KCND2_MOUSE
NC score	0.007042 (rank : 192)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	196	Target Neighborhood Hits	156	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

MRIP_MOUSE
NC score	0.006988 (rank : 193)	θ value	8.99809 (rank : 188)
Query Neighborhood Hits	196	Target Neighborhood Hits	569	Shared Neighborhood Hits	22
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

UB2E2_MOUSE
NC score	0.006637 (rank : 194)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	196	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q91W82	Gene names	Ube2e2
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2).

UB2E2_HUMAN
NC score	0.006539 (rank : 195)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	196	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LR5	Gene names	UBE2E2, UBCH8
Domain Architecture
Description	Ubiquitin-conjugating enzyme E2 E2 (EC 6.3.2.19) (Ubiquitin-protein ligase E2) (Ubiquitin carrier protein E2) (UbcH8).

PAX3_MOUSE
NC score	0.006418 (rank : 196)	θ value	8.99809 (rank : 190)
Query Neighborhood Hits	196	Target Neighborhood Hits	478	Shared Neighborhood Hits	18
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

DDX21_MOUSE
NC score	0.005522 (rank : 197)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	196	Target Neighborhood Hits	350	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

ZEP2_MOUSE
NC score	0.004771 (rank : 198)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	196	Target Neighborhood Hits	964	Shared Neighborhood Hits	31
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

KBTB3_HUMAN
NC score	0.004460 (rank : 199)	θ value	4.03905 (rank : 110)
Query Neighborhood Hits	196	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NAB2, Q86X38, Q96NK5	Gene names	KBTBD3, BKLHD3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

KBTB3_MOUSE
NC score	0.003727 (rank : 200)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	196	Target Neighborhood Hits	176	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHI4, Q8BNJ8	Gene names	Kbtbd3, Bklhd3
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 3 (BTB and kelch domain-containing protein 3).

GLI2_HUMAN
NC score	0.002715 (rank : 201)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	196	Target Neighborhood Hits	971	Shared Neighborhood Hits	30
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

MARK2_HUMAN
NC score	0.002476 (rank : 202)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	196	Target Neighborhood Hits	1056	Shared Neighborhood Hits	26
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

PDLI7_MOUSE
NC score	0.001834 (rank : 203)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	196	Target Neighborhood Hits	279	Shared Neighborhood Hits	6
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

MRCKG_MOUSE
NC score	0.001744 (rank : 204)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	196	Target Neighborhood Hits	1466	Shared Neighborhood Hits	34
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

TCF8_MOUSE
NC score	0.000921 (rank : 205)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	196	Target Neighborhood Hits	1067	Shared Neighborhood Hits	27
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

PCDH7_HUMAN
NC score	0.000802 (rank : 206)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	196	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	O60245, O60246, O60247	Gene names	PCDH7, BHPCDH
Domain Architecture
Description	Protocadherin-7 precursor (Brain-heart protocadherin) (BH-Pcdh).

MARK2_MOUSE
NC score	0.000743 (rank : 207)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	196	Target Neighborhood Hits	1018	Shared Neighborhood Hits	32
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

ACK1_HUMAN
NC score	0.000572 (rank : 208)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	196	Target Neighborhood Hits	1140	Shared Neighborhood Hits	38
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

MAST1_MOUSE
NC score	0.000465 (rank : 209)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	196	Target Neighborhood Hits	1123	Shared Neighborhood Hits	26
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

HIPK1_HUMAN
NC score	0.000143 (rank : 210)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	196	Target Neighborhood Hits	843	Shared Neighborhood Hits	17
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

CD2L6_HUMAN
NC score	-0.001130 (rank : 211)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	196	Target Neighborhood Hits	844	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BWU1, Q5JQZ7, Q5JR00, Q8TC78, Q9UPX2	Gene names	CDC2L6, CDK11, KIAA1028
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 6 (EC 2.7.11.22) (CDC2- related protein kinase 6) (Death-preventing kinase) (Cyclin-dependent kinase 11).

GLI3_MOUSE
NC score	-0.002137 (rank : 212)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	196	Target Neighborhood Hits	807	Shared Neighborhood Hits	13
SwissProt Accessions	Q61602	Gene names	Gli3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI3.