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Network neighborhood for query Sequence : UBP53_HUMAN

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UBP53_HUMAN
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP53_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
θ value	0 (rank : 2)	NC score	0.944994 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	188	Shared Neighborhood Hits	26
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP54_MOUSE
θ value	3.39372e-140 (rank : 3)	NC score	0.953313 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_HUMAN
θ value	4.43234e-140 (rank : 4)	NC score	0.953092 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP18_MOUSE
θ value	0.00869519 (rank : 5)	NC score	0.183495 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP35_HUMAN
θ value	0.0193708 (rank : 6)	NC score	0.125463 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP18_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.102556 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP22_HUMAN
θ value	0.0961366 (rank : 8)	NC score	0.098739 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	0.0961366 (rank : 9)	NC score	0.098806 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

YETS2_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.046775 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

BPAEA_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.017530 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	1369	Shared Neighborhood Hits	16
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

UBP36_HUMAN
θ value	0.21417 (rank : 12)	NC score	0.090968 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	232	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP38_MOUSE
θ value	0.21417 (rank : 13)	NC score	0.093047 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBPW_MOUSE
θ value	0.21417 (rank : 14)	NC score	0.109268 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

PCLO_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.021954 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	2275	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NPBL_MOUSE
θ value	0.47712 (rank : 16)	NC score	0.034889 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	1041	Shared Neighborhood Hits	21
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

UBP51_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.091330 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

PRP4B_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.011431 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	1030	Shared Neighborhood Hits	11
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

UBP50_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.065735 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

HMMR_HUMAN
θ value	1.06291 (rank : 20)	NC score	0.013351 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	1082	Shared Neighborhood Hits	10
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

M3K4_MOUSE
θ value	1.06291 (rank : 21)	NC score	0.004304 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	924	Shared Neighborhood Hits	6
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

LV1B_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.012129 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P01724	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104 precursor.

PRP4B_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.017529 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

ITA5_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.014354 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

JARD2_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.031830 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

UBP4_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.053404 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

ATRX_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.027571 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	842	Shared Neighborhood Hits	15
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

GCC2_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.011686 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	1558	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

IWS1_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.022747 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	1241	Shared Neighborhood Hits	22
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

RBP24_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.011626 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	1559	Shared Neighborhood Hits	15
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

UBP11_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.052682 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP38_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.079355 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

ZMYM6_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.020763 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	O95789, Q96IY0	Gene names	ZMYM6, ZNF258
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 6 (Zinc finger protein 258).

AFF4_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.045273 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

BCL7A_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.022249 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

DC1I1_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.013768 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

DSPP_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.055331 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	645	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LV1E_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.010937 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	P01727	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V region S43 precursor.

NIPBL_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.028854 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	1311	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ARX_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.004298 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	401	Shared Neighborhood Hits	3
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

JARD2_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.023899 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

LRCH3_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.007198 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

SCN2A_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.006140 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SPAT2_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.028899 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

UBP15_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.056075 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.056064 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

ZN599_HUMAN
θ value	4.03905 (rank : 47)	NC score	-0.000965 (rank : 80)
Query Neighborhood Hits	71	Target Neighborhood Hits	744	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NL3, Q569K0, Q5PRG1	Gene names	ZNF599
Domain Architecture	No domain graphic available
Description	Zinc finger protein 599.

BNI3L_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.023258 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O60238	Gene names	BNIP3L, BNIP3A, BNIP3H, NIX
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X) (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A).

FYCO1_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.008636 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	1149	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GRAP1_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.008062 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	1234	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

ITA5_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.012113 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P11688	Gene names	Itga5
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

KNTC1_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.015824 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P50748	Gene names	KNTC1, KIAA0166
Domain Architecture	No domain graphic available
Description	Kinetochore-associated protein 1 (Rough deal homolog) (hRod) (HsROD) (Rod).

UBP33_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.054359 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

YLPM1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.021536 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	670	Shared Neighborhood Hits	16
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BNI3L_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.021392 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2F7, Q545J6	Gene names	Bnip3l, Nix
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X).

FIGN_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.007283 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

HRX_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.010261 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	825	Shared Neighborhood Hits	11
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LV1A_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.010683 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	222	Shared Neighborhood Hits	5
SwissProt Accessions	P01723	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V region precursor.

PKN3_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.001098 (rank : 79)
Query Neighborhood Hits	71	Target Neighborhood Hits	893	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PPIG_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.012031 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	670	Shared Neighborhood Hits	17
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TNF13_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.015768 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).

DZIP3_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.008706 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	414	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

FBX46_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.010097 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

LV1D_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.008780 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	243	Shared Neighborhood Hits	5
SwissProt Accessions	P01726	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V region H2020 precursor.

NCOA1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.010506 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

NCOA1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.010532 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NELL2_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.001882 (rank : 78)
Query Neighborhood Hits	71	Target Neighborhood Hits	436	Shared Neighborhood Hits	2
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PHF3_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.014394 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

TADBP_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.011147 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q13148, Q96DJ0	Gene names	TARDBP, TDP43
Domain Architecture
Description	TAR DNA-binding protein 43 (TDP-43).

TARA_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.012246 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	1133	Shared Neighborhood Hits	18
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

UBP42_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.056040 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	445	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UB17L_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.050436 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP12_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.055024 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP44_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.057148 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP46_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.062318 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.062318 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP47_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.051101 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP49_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.052009 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.065548 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP50_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.051577 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

Hits sorted by NC score

UBP53_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP54_MOUSE
NC score	0.953313 (rank : 2)	θ value	3.39372e-140 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	19	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_HUMAN
NC score	0.953092 (rank : 3)	θ value	4.43234e-140 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP53_MOUSE
NC score	0.944994 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	188	Shared Neighborhood Hits	26
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP18_MOUSE
NC score	0.183495 (rank : 5)	θ value	0.00869519 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	77	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP35_HUMAN
NC score	0.125463 (rank : 6)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBPW_MOUSE
NC score	0.109268 (rank : 7)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	22
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP18_HUMAN
NC score	0.102556 (rank : 8)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP22_MOUSE
NC score	0.098806 (rank : 9)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
NC score	0.098739 (rank : 10)	θ value	0.0961366 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	87	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP38_MOUSE
NC score	0.093047 (rank : 11)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP51_HUMAN
NC score	0.091330 (rank : 12)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	162	Shared Neighborhood Hits	21
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP36_HUMAN
NC score	0.090968 (rank : 13)	θ value	0.21417 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	232	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP38_HUMAN
NC score	0.079355 (rank : 14)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	97	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP50_MOUSE
NC score	0.065735 (rank : 15)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP49_MOUSE
NC score	0.065548 (rank : 16)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	71	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP46_HUMAN
NC score	0.062318 (rank : 17)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.062318 (rank : 18)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	81	Shared Neighborhood Hits	19
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP44_HUMAN
NC score	0.057148 (rank : 19)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	91	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP15_HUMAN
NC score	0.056075 (rank : 20)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
NC score	0.056064 (rank : 21)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	19
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP42_HUMAN
NC score	0.056040 (rank : 22)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	445	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

DSPP_HUMAN
NC score	0.055331 (rank : 23)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	645	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

UBP12_HUMAN
NC score	0.055024 (rank : 24)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	85	Shared Neighborhood Hits	19
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP33_HUMAN
NC score	0.054359 (rank : 25)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	157	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP4_HUMAN
NC score	0.053404 (rank : 26)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP11_HUMAN
NC score	0.052682 (rank : 27)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	18
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP49_HUMAN
NC score	0.052009 (rank : 28)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	71	Target Neighborhood Hits	100	Shared Neighborhood Hits	19
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP50_HUMAN
NC score	0.051577 (rank : 29)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	71	Target Neighborhood Hits	75	Shared Neighborhood Hits	17
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP47_HUMAN
NC score	0.051101 (rank : 30)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	149	Shared Neighborhood Hits	19
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UB17L_HUMAN
NC score	0.050436 (rank : 31)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

YETS2_HUMAN
NC score	0.046775 (rank : 32)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	212	Shared Neighborhood Hits	7
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

AFF4_MOUSE
NC score	0.045273 (rank : 33)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	581	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

NPBL_MOUSE
NC score	0.034889 (rank : 34)	θ value	0.47712 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	1041	Shared Neighborhood Hits	21
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

JARD2_HUMAN
NC score	0.031830 (rank : 35)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

SPAT2_HUMAN
NC score	0.028899 (rank : 36)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

NIPBL_HUMAN
NC score	0.028854 (rank : 37)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	1311	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

ATRX_HUMAN
NC score	0.027571 (rank : 38)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	842	Shared Neighborhood Hits	15
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

JARD2_MOUSE
NC score	0.023899 (rank : 39)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	169	Shared Neighborhood Hits	6
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

BNI3L_HUMAN
NC score	0.023258 (rank : 40)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	O60238	Gene names	BNIP3L, BNIP3A, BNIP3H, NIX
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X) (BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A).

IWS1_HUMAN
NC score	0.022747 (rank : 41)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	1241	Shared Neighborhood Hits	22
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BCL7A_HUMAN
NC score	0.022249 (rank : 42)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q4VC05, Q13843	Gene names	BCL7A
Domain Architecture	No domain graphic available
Description	B-cell CLL/lymphoma 7 protein family member A.

PCLO_MOUSE
NC score	0.021954 (rank : 43)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	2275	Shared Neighborhood Hits	26
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

YLPM1_HUMAN
NC score	0.021536 (rank : 44)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	670	Shared Neighborhood Hits	16
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BNI3L_MOUSE
NC score	0.021392 (rank : 45)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z2F7, Q545J6	Gene names	Bnip3l, Nix
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3L) (NIP3-like protein X).

ZMYM6_HUMAN
NC score	0.020763 (rank : 46)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	O95789, Q96IY0	Gene names	ZMYM6, ZNF258
Domain Architecture	No domain graphic available
Description	Zinc finger MYM-type protein 6 (Zinc finger protein 258).

BPAEA_HUMAN
NC score	0.017530 (rank : 47)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	1369	Shared Neighborhood Hits	16
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

PRP4B_MOUSE
NC score	0.017529 (rank : 48)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	1040	Shared Neighborhood Hits	15
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

KNTC1_HUMAN
NC score	0.015824 (rank : 49)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	67	Shared Neighborhood Hits	3
SwissProt Accessions	P50748	Gene names	KNTC1, KIAA0166
Domain Architecture	No domain graphic available
Description	Kinetochore-associated protein 1 (Rough deal homolog) (hRod) (HsROD) (Rod).

TNF13_HUMAN
NC score	0.015768 (rank : 50)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O75888, Q96HV6, Q9P1M8, Q9P1M9	Gene names	TNFSF13, APRIL, TALL2, ZTNF2
Domain Architecture
Description	Tumor necrosis factor ligand superfamily member 13 precursor (A proliferation-inducing ligand) (APRIL) (TNF- and APOL-related leukocyte expressed ligand 2) (TALL-2) (TNF-related death ligand 1) (TRDL-1) (CD256 antigen).

PHF3_HUMAN
NC score	0.014394 (rank : 51)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ITA5_HUMAN
NC score	0.014354 (rank : 52)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

DC1I1_HUMAN
NC score	0.013768 (rank : 53)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O14576, Q9Y2X1	Gene names	DYNC1I1, DNCI1, DNCIC1
Domain Architecture
Description	Cytoplasmic dynein 1 intermediate chain 1 (Dynein intermediate chain 1, cytosolic) (DH IC-1) (Cytoplasmic dynein intermediate chain 1).

HMMR_HUMAN
NC score	0.013351 (rank : 54)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1082	Shared Neighborhood Hits	10
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

TARA_MOUSE
NC score	0.012246 (rank : 55)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	1133	Shared Neighborhood Hits	18
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

LV1B_MOUSE
NC score	0.012129 (rank : 56)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	258	Shared Neighborhood Hits	5
SwissProt Accessions	P01724	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V regions MOPC 104E/RPC20/J558/S104 precursor.

ITA5_MOUSE
NC score	0.012113 (rank : 57)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	3
SwissProt Accessions	P11688	Gene names	Itga5
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

PPIG_HUMAN
NC score	0.012031 (rank : 58)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	670	Shared Neighborhood Hits	17
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

GCC2_HUMAN
NC score	0.011686 (rank : 59)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	1558	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.011626 (rank : 60)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	1559	Shared Neighborhood Hits	15
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

PRP4B_HUMAN
NC score	0.011431 (rank : 61)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	1030	Shared Neighborhood Hits	11
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

TADBP_HUMAN
NC score	0.011147 (rank : 62)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	196	Shared Neighborhood Hits	3
SwissProt Accessions	Q13148, Q96DJ0	Gene names	TARDBP, TDP43
Domain Architecture
Description	TAR DNA-binding protein 43 (TDP-43).

LV1E_MOUSE
NC score	0.010937 (rank : 63)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	P01727	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V region S43 precursor.

LV1A_MOUSE
NC score	0.010683 (rank : 64)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	222	Shared Neighborhood Hits	5
SwissProt Accessions	P01723	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V region precursor.

NCOA1_MOUSE
NC score	0.010532 (rank : 65)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	196	Shared Neighborhood Hits	5
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

NCOA1_HUMAN
NC score	0.010506 (rank : 66)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q15788, O00150, O43792, O43793, Q13071, Q13420, Q6GVI5, Q7KYV3	Gene names	NCOA1, SRC1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (RIP160) (Protein Hin-2) (NY-REN-52 antigen).

HRX_HUMAN
NC score	0.010261 (rank : 67)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	825	Shared Neighborhood Hits	11
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

FBX46_MOUSE
NC score	0.010097 (rank : 68)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	139	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BG80	Gene names	Fbxo46, Fbx46, Fbxo34l
Domain Architecture	No domain graphic available
Description	F-box only protein 46 (F-box only protein 34-like).

LV1D_MOUSE
NC score	0.008780 (rank : 69)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	243	Shared Neighborhood Hits	5
SwissProt Accessions	P01726	Gene names
Domain Architecture	No domain graphic available
Description	Ig lambda-1 chain V region H2020 precursor.

DZIP3_MOUSE
NC score	0.008706 (rank : 70)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	414	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

FYCO1_HUMAN
NC score	0.008636 (rank : 71)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	1149	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GRAP1_MOUSE
NC score	0.008062 (rank : 72)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	1234	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

FIGN_HUMAN
NC score	0.007283 (rank : 73)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	176	Shared Neighborhood Hits	5
SwissProt Accessions	Q5HY92, Q9H6M5, Q9NVZ9	Gene names	FIGN
Domain Architecture	No domain graphic available
Description	Fidgetin.

LRCH3_MOUSE
NC score	0.007198 (rank : 74)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	257	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BVU0, Q3U222, Q3UZ74	Gene names	Lrch3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 3 precursor.

SCN2A_HUMAN
NC score	0.006140 (rank : 75)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

M3K4_MOUSE
NC score	0.004304 (rank : 76)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	924	Shared Neighborhood Hits	6
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

ARX_HUMAN
NC score	0.004298 (rank : 77)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	401	Shared Neighborhood Hits	3
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

NELL2_MOUSE
NC score	0.001882 (rank : 78)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	436	Shared Neighborhood Hits	2
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PKN3_HUMAN
NC score	0.001098 (rank : 79)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	893	Shared Neighborhood Hits	7
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

ZN599_HUMAN
NC score	-0.000965 (rank : 80)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	744	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NL3, Q569K0, Q5PRG1	Gene names	ZNF599
Domain Architecture	No domain graphic available
Description	Zinc finger protein 599.