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Network neighborhood for query Sequence : UBP54_HUMAN

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UBP54_HUMAN
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP54_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
θ value	0 (rank : 2)	NC score	0.999385 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP53_HUMAN
θ value	4.43234e-140 (rank : 3)	NC score	0.953092 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
θ value	9.87422e-140 (rank : 4)	NC score	0.912108 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP18_MOUSE
θ value	6.43352e-06 (rank : 5)	NC score	0.200806 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBPW_MOUSE
θ value	0.00509761 (rank : 6)	NC score	0.127896 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP49_MOUSE
θ value	0.163984 (rank : 7)	NC score	0.099862 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP51_HUMAN
θ value	0.163984 (rank : 8)	NC score	0.105692 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP22_HUMAN
θ value	0.21417 (rank : 9)	NC score	0.111615 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_MOUSE
θ value	0.21417 (rank : 10)	NC score	0.111817 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP44_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.091214 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP46_HUMAN
θ value	0.365318 (rank : 12)	NC score	0.090134 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	0.365318 (rank : 13)	NC score	0.090134 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP49_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.085900 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP35_HUMAN
θ value	2.36792 (rank : 15)	NC score	0.100142 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP12_HUMAN
θ value	3.0926 (rank : 16)	NC score	0.080122 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

ATS20_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.004593 (rank : 43)
Query Neighborhood Hits	21	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

CRIM1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.008426 (rank : 42)
Query Neighborhood Hits	21	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

UBP36_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.093737 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	232	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP40_HUMAN
θ value	5.27518 (rank : 20)	NC score	0.060081 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

TXN4B_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.020729 (rank : 41)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NX01	Gene names	TXNL4B, DIM2, DLP
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 4B (Dim1-like protein).

UB17L_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.059392 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP16_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.052727 (rank : 35)
Query Neighborhood Hits	21	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP18_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.096780 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP1_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.050986 (rank : 40)
Query Neighborhood Hits	21	Target Neighborhood Hits	259	Shared Neighborhood Hits	14
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP20_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.051106 (rank : 39)
Query Neighborhood Hits	21	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP21_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.054031 (rank : 30)
Query Neighborhood Hits	21	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
θ value	θ > 10 (rank : 28)	NC score	0.053085 (rank : 33)
Query Neighborhood Hits	21	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP2_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.054195 (rank : 28)
Query Neighborhood Hits	21	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.054194 (rank : 29)
Query Neighborhood Hits	21	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP33_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.052950 (rank : 34)
Query Neighborhood Hits	21	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP38_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.051928 (rank : 38)
Query Neighborhood Hits	21	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP38_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.063282 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP3_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.058904 (rank : 25)
Query Neighborhood Hits	21	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.058993 (rank : 24)
Query Neighborhood Hits	21	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP42_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.062935 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	445	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP47_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.055938 (rank : 26)
Query Neighborhood Hits	21	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP47_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.053671 (rank : 32)
Query Neighborhood Hits	21	Target Neighborhood Hits	135	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP48_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.052154 (rank : 37)
Query Neighborhood Hits	21	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.052200 (rank : 36)
Query Neighborhood Hits	21	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP50_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.053790 (rank : 31)
Query Neighborhood Hits	21	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP50_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.065565 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP7_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.054661 (rank : 27)
Query Neighborhood Hits	21	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

Hits sorted by NC score

UBP54_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP54_MOUSE
NC score	0.999385 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BL06, Q8BZ28	Gene names	Usp54
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

UBP53_HUMAN
NC score	0.953092 (rank : 3)	θ value	4.43234e-140 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	71	Shared Neighborhood Hits	11
SwissProt Accessions	Q70EK8, Q68DA5, Q8WVQ5, Q9P2J7	Gene names	USP53, KIAA1350
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53).

UBP53_MOUSE
NC score	0.912108 (rank : 4)	θ value	9.87422e-140 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	188	Shared Neighborhood Hits	12
SwissProt Accessions	P15975, Q8CB37, Q8R251	Gene names	Usp53, Phxr3
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin- specific peptidase 53) (Per-hexamer repeat protein 3).

UBP18_MOUSE
NC score	0.200806 (rank : 5)	θ value	6.43352e-06 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	77	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBPW_MOUSE
NC score	0.127896 (rank : 6)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	89	Shared Neighborhood Hits	18
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP22_MOUSE
NC score	0.111817 (rank : 7)	θ value	0.21417 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP22_HUMAN
NC score	0.111615 (rank : 8)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	87	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.105692 (rank : 9)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	162	Shared Neighborhood Hits	18
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP35_HUMAN
NC score	0.100142 (rank : 10)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	223	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP49_MOUSE
NC score	0.099862 (rank : 11)	θ value	0.163984 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP18_HUMAN
NC score	0.096780 (rank : 12)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP36_HUMAN
NC score	0.093737 (rank : 13)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	232	Shared Neighborhood Hits	18
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP44_HUMAN
NC score	0.091214 (rank : 14)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	91	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP46_HUMAN
NC score	0.090134 (rank : 15)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.090134 (rank : 16)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	16
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP49_HUMAN
NC score	0.085900 (rank : 17)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP12_HUMAN
NC score	0.080122 (rank : 18)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	85	Shared Neighborhood Hits	16
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP50_MOUSE
NC score	0.065565 (rank : 19)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	21	Target Neighborhood Hits	80	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP38_MOUSE
NC score	0.063282 (rank : 20)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	21	Target Neighborhood Hits	100	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP42_HUMAN
NC score	0.062935 (rank : 21)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	21	Target Neighborhood Hits	445	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP40_HUMAN
NC score	0.060081 (rank : 22)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	81	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UB17L_HUMAN
NC score	0.059392 (rank : 23)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	21	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP3_MOUSE
NC score	0.058993 (rank : 24)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	21	Target Neighborhood Hits	89	Shared Neighborhood Hits	14
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP3_HUMAN
NC score	0.058904 (rank : 25)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	21	Target Neighborhood Hits	88	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP47_HUMAN
NC score	0.055938 (rank : 26)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	21	Target Neighborhood Hits	149	Shared Neighborhood Hits	15
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP7_HUMAN
NC score	0.054661 (rank : 27)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	21	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP2_HUMAN
NC score	0.054195 (rank : 28)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	21	Target Neighborhood Hits	84	Shared Neighborhood Hits	14
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_MOUSE
NC score	0.054194 (rank : 29)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	21	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP21_HUMAN
NC score	0.054031 (rank : 30)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	21	Target Neighborhood Hits	95	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP50_HUMAN
NC score	0.053790 (rank : 31)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	21	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP47_MOUSE
NC score	0.053671 (rank : 32)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	21	Target Neighborhood Hits	135	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP21_MOUSE
NC score	0.053085 (rank : 33)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	21	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP33_HUMAN
NC score	0.052950 (rank : 34)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	21	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP16_HUMAN
NC score	0.052727 (rank : 35)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	21	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP48_MOUSE
NC score	0.052200 (rank : 36)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	21	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_HUMAN
NC score	0.052154 (rank : 37)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	21	Target Neighborhood Hits	101	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP38_HUMAN
NC score	0.051928 (rank : 38)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	21	Target Neighborhood Hits	97	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP20_HUMAN
NC score	0.051106 (rank : 39)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	21	Target Neighborhood Hits	113	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP1_HUMAN
NC score	0.050986 (rank : 40)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	21	Target Neighborhood Hits	259	Shared Neighborhood Hits	14
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

TXN4B_HUMAN
NC score	0.020729 (rank : 41)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NX01	Gene names	TXNL4B, DIM2, DLP
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 4B (Dim1-like protein).

CRIM1_HUMAN
NC score	0.008426 (rank : 42)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ATS20_MOUSE
NC score	0.004593 (rank : 43)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	225	Shared Neighborhood Hits	2
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).