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Network neighborhood for query Sequence : CRIM1_HUMAN

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CRIM1_HUMAN
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CRIM1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	362	Target Neighborhood Hits	362	Shared Neighborhood Hits	362
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

FRAS1_MOUSE
θ value	1.85459e-37 (rank : 2)	NC score	0.621033 (rank : 6)
Query Neighborhood Hits	362	Target Neighborhood Hits	747	Shared Neighborhood Hits	269
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NELL1_HUMAN
θ value	1.73584e-35 (rank : 3)	NC score	0.598281 (rank : 10)
Query Neighborhood Hits	362	Target Neighborhood Hits	451	Shared Neighborhood Hits	226
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FRAS1_HUMAN
θ value	2.26708e-35 (rank : 4)	NC score	0.623302 (rank : 4)
Query Neighborhood Hits	362	Target Neighborhood Hits	759	Shared Neighborhood Hits	271
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

BMPER_HUMAN
θ value	1.16434e-31 (rank : 5)	NC score	0.648596 (rank : 3)
Query Neighborhood Hits	362	Target Neighborhood Hits	175	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	1.08979e-29 (rank : 6)	NC score	0.670515 (rank : 2)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

NELL2_MOUSE
θ value	8.63488e-27 (rank : 7)	NC score	0.574861 (rank : 12)
Query Neighborhood Hits	362	Target Neighborhood Hits	436	Shared Neighborhood Hits	219
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NELL2_HUMAN
θ value	1.24688e-25 (rank : 8)	NC score	0.569386 (rank : 14)
Query Neighborhood Hits	362	Target Neighborhood Hits	449	Shared Neighborhood Hits	216
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CRDL2_MOUSE
θ value	4.58923e-20 (rank : 9)	NC score	0.577406 (rank : 11)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CRDL1_MOUSE
θ value	1.02238e-19 (rank : 10)	NC score	0.543014 (rank : 21)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_HUMAN
θ value	2.97466e-19 (rank : 11)	NC score	0.541795 (rank : 22)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	8.65492e-19 (rank : 12)	NC score	0.562565 (rank : 17)
Query Neighborhood Hits	362	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

ZAN_MOUSE
θ value	1.13037e-18 (rank : 13)	NC score	0.618361 (rank : 7)
Query Neighborhood Hits	362	Target Neighborhood Hits	808	Shared Neighborhood Hits	291
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CHRD_HUMAN
θ value	2.35696e-16 (rank : 14)	NC score	0.522581 (rank : 28)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

VWF_MOUSE
θ value	4.02038e-16 (rank : 15)	NC score	0.490874 (rank : 46)
Query Neighborhood Hits	362	Target Neighborhood Hits	381	Shared Neighborhood Hits	204
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MUC2_HUMAN
θ value	1.16975e-15 (rank : 16)	NC score	0.384557 (rank : 146)
Query Neighborhood Hits	362	Target Neighborhood Hits	906	Shared Neighborhood Hits	156
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

CHRD_MOUSE
θ value	1.99529e-15 (rank : 17)	NC score	0.515128 (rank : 34)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

VWF_HUMAN
θ value	1.99529e-15 (rank : 18)	NC score	0.517597 (rank : 31)
Query Neighborhood Hits	362	Target Neighborhood Hits	396	Shared Neighborhood Hits	202
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

JAG2_MOUSE
θ value	8.38298e-14 (rank : 19)	NC score	0.503858 (rank : 40)
Query Neighborhood Hits	362	Target Neighborhood Hits	504	Shared Neighborhood Hits	232
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NOTC1_HUMAN
θ value	8.38298e-14 (rank : 20)	NC score	0.480740 (rank : 59)
Query Neighborhood Hits	362	Target Neighborhood Hits	906	Shared Neighborhood Hits	245
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SSPO_MOUSE
θ value	2.43908e-13 (rank : 21)	NC score	0.483440 (rank : 55)
Query Neighborhood Hits	362	Target Neighborhood Hits	800	Shared Neighborhood Hits	287
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

NOTC1_MOUSE
θ value	9.26847e-13 (rank : 22)	NC score	0.493952 (rank : 45)
Query Neighborhood Hits	362	Target Neighborhood Hits	916	Shared Neighborhood Hits	249
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

JAG1_MOUSE
θ value	1.58096e-12 (rank : 23)	NC score	0.520736 (rank : 29)
Query Neighborhood Hits	362	Target Neighborhood Hits	518	Shared Neighborhood Hits	235
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

NOTC3_HUMAN
θ value	3.52202e-12 (rank : 24)	NC score	0.484732 (rank : 53)
Query Neighborhood Hits	362	Target Neighborhood Hits	1062	Shared Neighborhood Hits	255
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBN3_HUMAN
θ value	7.84624e-12 (rank : 25)	NC score	0.483812 (rank : 54)
Query Neighborhood Hits	362	Target Neighborhood Hits	543	Shared Neighborhood Hits	226
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

JAG1_HUMAN
θ value	1.33837e-11 (rank : 26)	NC score	0.522737 (rank : 27)
Query Neighborhood Hits	362	Target Neighborhood Hits	514	Shared Neighborhood Hits	238
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

TSP2_HUMAN
θ value	2.28291e-11 (rank : 27)	NC score	0.379302 (rank : 156)
Query Neighborhood Hits	362	Target Neighborhood Hits	359	Shared Neighborhood Hits	192
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

LAMA1_HUMAN
θ value	2.98157e-11 (rank : 28)	NC score	0.448030 (rank : 81)
Query Neighborhood Hits	362	Target Neighborhood Hits	804	Shared Neighborhood Hits	221
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TENX_HUMAN
θ value	2.98157e-11 (rank : 29)	NC score	0.436563 (rank : 93)
Query Neighborhood Hits	362	Target Neighborhood Hits	789	Shared Neighborhood Hits	251
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TSP1_HUMAN
θ value	2.98157e-11 (rank : 30)	NC score	0.405079 (rank : 133)
Query Neighborhood Hits	362	Target Neighborhood Hits	389	Shared Neighborhood Hits	196
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

USH2A_MOUSE
θ value	2.98157e-11 (rank : 31)	NC score	0.420965 (rank : 116)
Query Neighborhood Hits	362	Target Neighborhood Hits	626	Shared Neighborhood Hits	212
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

TSP1_MOUSE
θ value	3.89403e-11 (rank : 32)	NC score	0.403590 (rank : 134)
Query Neighborhood Hits	362	Target Neighborhood Hits	396	Shared Neighborhood Hits	196
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_MOUSE
θ value	1.47974e-10 (rank : 33)	NC score	0.380356 (rank : 154)
Query Neighborhood Hits	362	Target Neighborhood Hits	352	Shared Neighborhood Hits	189
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

LAMA1_MOUSE
θ value	3.29651e-10 (rank : 34)	NC score	0.454499 (rank : 75)
Query Neighborhood Hits	362	Target Neighborhood Hits	838	Shared Neighborhood Hits	227
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

JAG2_HUMAN
θ value	4.30538e-10 (rank : 35)	NC score	0.507194 (rank : 38)
Query Neighborhood Hits	362	Target Neighborhood Hits	491	Shared Neighborhood Hits	226
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

CO1A1_HUMAN
θ value	5.62301e-10 (rank : 36)	NC score	0.180812 (rank : 331)
Query Neighborhood Hits	362	Target Neighborhood Hits	475	Shared Neighborhood Hits	56
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

KR106_HUMAN
θ value	2.13673e-09 (rank : 37)	NC score	0.617930 (rank : 8)
Query Neighborhood Hits	362	Target Neighborhood Hits	347	Shared Neighborhood Hits	209
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

PCSK5_MOUSE
θ value	3.64472e-09 (rank : 38)	NC score	0.436515 (rank : 94)
Query Neighborhood Hits	362	Target Neighborhood Hits	613	Shared Neighborhood Hits	244
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

KR104_HUMAN
θ value	4.76016e-09 (rank : 39)	NC score	0.622755 (rank : 5)
Query Neighborhood Hits	362	Target Neighborhood Hits	313	Shared Neighborhood Hits	188
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NOTC2_MOUSE
θ value	6.21693e-09 (rank : 40)	NC score	0.467945 (rank : 64)
Query Neighborhood Hits	362	Target Neighborhood Hits	1069	Shared Neighborhood Hits	249
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

FBN1_HUMAN
θ value	8.11959e-09 (rank : 41)	NC score	0.487179 (rank : 50)
Query Neighborhood Hits	362	Target Neighborhood Hits	557	Shared Neighborhood Hits	230
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	1.06045e-08 (rank : 42)	NC score	0.487480 (rank : 49)
Query Neighborhood Hits	362	Target Neighborhood Hits	563	Shared Neighborhood Hits	232
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

RECK_MOUSE
θ value	1.38499e-08 (rank : 43)	NC score	0.374435 (rank : 159)
Query Neighborhood Hits	362	Target Neighborhood Hits	158	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

NOTC4_HUMAN
θ value	2.36244e-08 (rank : 44)	NC score	0.462747 (rank : 69)
Query Neighborhood Hits	362	Target Neighborhood Hits	905	Shared Neighborhood Hits	251
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KR107_HUMAN
θ value	3.08544e-08 (rank : 45)	NC score	0.611028 (rank : 9)
Query Neighborhood Hits	362	Target Neighborhood Hits	330	Shared Neighborhood Hits	200
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KRA45_HUMAN
θ value	3.08544e-08 (rank : 46)	NC score	0.507470 (rank : 37)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LAMA2_HUMAN
θ value	3.08544e-08 (rank : 47)	NC score	0.414167 (rank : 123)
Query Neighborhood Hits	362	Target Neighborhood Hits	1092	Shared Neighborhood Hits	222
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

NOTC3_MOUSE
θ value	4.0297e-08 (rank : 48)	NC score	0.479802 (rank : 60)
Query Neighborhood Hits	362	Target Neighborhood Hits	975	Shared Neighborhood Hits	247
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBN2_HUMAN
θ value	5.26297e-08 (rank : 49)	NC score	0.489216 (rank : 48)
Query Neighborhood Hits	362	Target Neighborhood Hits	560	Shared Neighborhood Hits	238
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MUC5B_HUMAN
θ value	5.26297e-08 (rank : 50)	NC score	0.500519 (rank : 43)
Query Neighborhood Hits	362	Target Neighborhood Hits	1020	Shared Neighborhood Hits	235
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LTBP2_MOUSE
θ value	6.87365e-08 (rank : 51)	NC score	0.457865 (rank : 72)
Query Neighborhood Hits	362	Target Neighborhood Hits	617	Shared Neighborhood Hits	212
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

FBN2_MOUSE
θ value	8.97725e-08 (rank : 52)	NC score	0.486346 (rank : 51)
Query Neighborhood Hits	362	Target Neighborhood Hits	549	Shared Neighborhood Hits	237
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KR10B_HUMAN
θ value	8.97725e-08 (rank : 53)	NC score	0.548153 (rank : 19)
Query Neighborhood Hits	362	Target Neighborhood Hits	269	Shared Neighborhood Hits	174
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMB1_MOUSE
θ value	8.97725e-08 (rank : 54)	NC score	0.416237 (rank : 121)
Query Neighborhood Hits	362	Target Neighborhood Hits	919	Shared Neighborhood Hits	193
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

TENA_HUMAN
θ value	8.97725e-08 (rank : 55)	NC score	0.434993 (rank : 97)
Query Neighborhood Hits	362	Target Neighborhood Hits	631	Shared Neighborhood Hits	226
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

KR412_HUMAN
θ value	1.17247e-07 (rank : 56)	NC score	0.485288 (rank : 52)
Query Neighborhood Hits	362	Target Neighborhood Hits	178	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

TENA_MOUSE
θ value	1.17247e-07 (rank : 57)	NC score	0.426534 (rank : 109)
Query Neighborhood Hits	362	Target Neighborhood Hits	596	Shared Neighborhood Hits	228
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

ESM1_HUMAN
θ value	1.53129e-07 (rank : 58)	NC score	0.324087 (rank : 196)
Query Neighborhood Hits	362	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

KR108_HUMAN
θ value	1.99992e-07 (rank : 59)	NC score	0.527628 (rank : 25)
Query Neighborhood Hits	362	Target Neighborhood Hits	226	Shared Neighborhood Hits	153
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMA5_HUMAN
θ value	1.99992e-07 (rank : 60)	NC score	0.474564 (rank : 63)
Query Neighborhood Hits	362	Target Neighborhood Hits	976	Shared Neighborhood Hits	242
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC2_HUMAN
θ value	2.61198e-07 (rank : 61)	NC score	0.465605 (rank : 67)
Query Neighborhood Hits	362	Target Neighborhood Hits	1113	Shared Neighborhood Hits	260
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR101_HUMAN
θ value	3.41135e-07 (rank : 62)	NC score	0.549537 (rank : 18)
Query Neighborhood Hits	362	Target Neighborhood Hits	261	Shared Neighborhood Hits	161
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR105_HUMAN
θ value	3.41135e-07 (rank : 63)	NC score	0.573114 (rank : 13)
Query Neighborhood Hits	362	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

LAMA5_MOUSE
θ value	3.41135e-07 (rank : 64)	NC score	0.481394 (rank : 58)
Query Neighborhood Hits	362	Target Neighborhood Hits	828	Shared Neighborhood Hits	256
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

MEGF6_HUMAN
θ value	3.41135e-07 (rank : 65)	NC score	0.538340 (rank : 23)
Query Neighborhood Hits	362	Target Neighborhood Hits	671	Shared Neighborhood Hits	283
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

CO5A2_HUMAN
θ value	4.45536e-07 (rank : 66)	NC score	0.150045 (rank : 373)
Query Neighborhood Hits	362	Target Neighborhood Hits	760	Shared Neighborhood Hits	67
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

USH2A_HUMAN
θ value	4.45536e-07 (rank : 67)	NC score	0.379594 (rank : 155)
Query Neighborhood Hits	362	Target Neighborhood Hits	600	Shared Neighborhood Hits	185
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

CO1A1_MOUSE
θ value	7.59969e-07 (rank : 68)	NC score	0.182248 (rank : 329)
Query Neighborhood Hits	362	Target Neighborhood Hits	457	Shared Neighborhood Hits	59
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

CO2A1_MOUSE
θ value	7.59969e-07 (rank : 69)	NC score	0.162651 (rank : 355)
Query Neighborhood Hits	362	Target Neighborhood Hits	483	Shared Neighborhood Hits	40
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO3A1_HUMAN
θ value	7.59969e-07 (rank : 70)	NC score	0.168212 (rank : 347)
Query Neighborhood Hits	362	Target Neighborhood Hits	452	Shared Neighborhood Hits	39
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

HTRA3_HUMAN
θ value	9.92553e-07 (rank : 71)	NC score	0.190748 (rank : 318)
Query Neighborhood Hits	362	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

KR414_HUMAN
θ value	9.92553e-07 (rank : 72)	NC score	0.477596 (rank : 62)
Query Neighborhood Hits	362	Target Neighborhood Hits	199	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LAMB2_MOUSE
θ value	9.92553e-07 (rank : 73)	NC score	0.442758 (rank : 87)
Query Neighborhood Hits	362	Target Neighborhood Hits	722	Shared Neighborhood Hits	202
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

MEGF9_MOUSE
θ value	9.92553e-07 (rank : 74)	NC score	0.436264 (rank : 95)
Query Neighborhood Hits	362	Target Neighborhood Hits	896	Shared Neighborhood Hits	175
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KR109_HUMAN
θ value	1.29631e-06 (rank : 75)	NC score	0.531962 (rank : 24)
Query Neighborhood Hits	362	Target Neighborhood Hits	226	Shared Neighborhood Hits	163
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

RECK_HUMAN
θ value	1.29631e-06 (rank : 76)	NC score	0.385842 (rank : 143)
Query Neighborhood Hits	362	Target Neighborhood Hits	189	Shared Neighborhood Hits	117
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

ECM2_HUMAN
θ value	1.69304e-06 (rank : 77)	NC score	0.153015 (rank : 371)
Query Neighborhood Hits	362	Target Neighborhood Hits	402	Shared Neighborhood Hits	56
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

KRA47_HUMAN
θ value	1.69304e-06 (rank : 78)	NC score	0.502901 (rank : 41)
Query Neighborhood Hits	362	Target Neighborhood Hits	204	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

LTBP4_MOUSE
θ value	1.69304e-06 (rank : 79)	NC score	0.464485 (rank : 68)
Query Neighborhood Hits	362	Target Neighborhood Hits	607	Shared Neighborhood Hits	207
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

CO3A1_MOUSE
θ value	2.21117e-06 (rank : 80)	NC score	0.165260 (rank : 351)
Query Neighborhood Hits	362	Target Neighborhood Hits	466	Shared Neighborhood Hits	40
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

KR103_HUMAN
θ value	2.21117e-06 (rank : 81)	NC score	0.482195 (rank : 57)
Query Neighborhood Hits	362	Target Neighborhood Hits	212	Shared Neighborhood Hits	155
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KAZD1_MOUSE
θ value	2.88788e-06 (rank : 82)	NC score	0.170314 (rank : 342)
Query Neighborhood Hits	362	Target Neighborhood Hits	281	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KR10C_HUMAN
θ value	3.77169e-06 (rank : 83)	NC score	0.502341 (rank : 42)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	148
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KRA53_HUMAN
θ value	3.77169e-06 (rank : 84)	NC score	0.565935 (rank : 15)
Query Neighborhood Hits	362	Target Neighborhood Hits	331	Shared Neighborhood Hits	199
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

LAMB1_HUMAN
θ value	6.43352e-06 (rank : 85)	NC score	0.401546 (rank : 137)
Query Neighborhood Hits	362	Target Neighborhood Hits	1018	Shared Neighborhood Hits	199
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

HTRA1_MOUSE
θ value	8.40245e-06 (rank : 86)	NC score	0.193842 (rank : 315)
Query Neighborhood Hits	362	Target Neighborhood Hits	140	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

LAMB2_HUMAN
θ value	8.40245e-06 (rank : 87)	NC score	0.444899 (rank : 83)
Query Neighborhood Hits	362	Target Neighborhood Hits	692	Shared Neighborhood Hits	198
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

HTRA3_MOUSE
θ value	1.43324e-05 (rank : 88)	NC score	0.186994 (rank : 323)
Query Neighborhood Hits	362	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

KRA44_HUMAN
θ value	1.43324e-05 (rank : 89)	NC score	0.442499 (rank : 88)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

LAMC3_HUMAN
θ value	1.43324e-05 (rank : 90)	NC score	0.440463 (rank : 91)
Query Neighborhood Hits	362	Target Neighborhood Hits	588	Shared Neighborhood Hits	212
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

KAZD1_HUMAN
θ value	1.87187e-05 (rank : 91)	NC score	0.178720 (rank : 332)
Query Neighborhood Hits	362	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LTB1L_HUMAN
θ value	2.44474e-05 (rank : 92)	NC score	0.432036 (rank : 101)
Query Neighborhood Hits	362	Target Neighborhood Hits	553	Shared Neighborhood Hits	198
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	2.44474e-05 (rank : 93)	NC score	0.429273 (rank : 103)
Query Neighborhood Hits	362	Target Neighborhood Hits	502	Shared Neighborhood Hits	185
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

FBLN2_MOUSE
θ value	3.19293e-05 (rank : 94)	NC score	0.413212 (rank : 126)
Query Neighborhood Hits	362	Target Neighborhood Hits	505	Shared Neighborhood Hits	179
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

KR102_HUMAN
θ value	3.19293e-05 (rank : 95)	NC score	0.524968 (rank : 26)
Query Neighborhood Hits	362	Target Neighborhood Hits	264	Shared Neighborhood Hits	169
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

LTBP2_HUMAN
θ value	3.19293e-05 (rank : 96)	NC score	0.459446 (rank : 70)
Query Neighborhood Hits	362	Target Neighborhood Hits	552	Shared Neighborhood Hits	216
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KR10A_HUMAN
θ value	4.1701e-05 (rank : 97)	NC score	0.505129 (rank : 39)
Query Neighborhood Hits	362	Target Neighborhood Hits	232	Shared Neighborhood Hits	161
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

SREC2_MOUSE
θ value	4.1701e-05 (rank : 98)	NC score	0.519030 (rank : 30)
Query Neighborhood Hits	362	Target Neighborhood Hits	605	Shared Neighborhood Hits	242
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

LAMC1_HUMAN
θ value	5.44631e-05 (rank : 99)	NC score	0.395464 (rank : 140)
Query Neighborhood Hits	362	Target Neighborhood Hits	922	Shared Neighborhood Hits	204
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PGBM_HUMAN
θ value	7.1131e-05 (rank : 100)	NC score	0.283089 (rank : 248)
Query Neighborhood Hits	362	Target Neighborhood Hits	1113	Shared Neighborhood Hits	211
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SREC_HUMAN
θ value	7.1131e-05 (rank : 101)	NC score	0.564006 (rank : 16)
Query Neighborhood Hits	362	Target Neighborhood Hits	645	Shared Neighborhood Hits	258
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

WISP1_HUMAN
θ value	7.1131e-05 (rank : 102)	NC score	0.278444 (rank : 256)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

HTRA1_HUMAN
θ value	9.29e-05 (rank : 103)	NC score	0.207121 (rank : 304)
Query Neighborhood Hits	362	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

IBP7_MOUSE
θ value	0.000121331 (rank : 104)	NC score	0.183970 (rank : 328)
Query Neighborhood Hits	362	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

KRA58_HUMAN
θ value	0.000121331 (rank : 105)	NC score	0.546937 (rank : 20)
Query Neighborhood Hits	362	Target Neighborhood Hits	324	Shared Neighborhood Hits	190
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA3_MOUSE
θ value	0.000121331 (rank : 106)	NC score	0.383393 (rank : 148)
Query Neighborhood Hits	362	Target Neighborhood Hits	859	Shared Neighborhood Hits	206
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMC3_MOUSE
θ value	0.000121331 (rank : 107)	NC score	0.433409 (rank : 100)
Query Neighborhood Hits	362	Target Neighborhood Hits	624	Shared Neighborhood Hits	199
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

AGRIN_HUMAN
θ value	0.000158464 (rank : 108)	NC score	0.478374 (rank : 61)
Query Neighborhood Hits	362	Target Neighborhood Hits	582	Shared Neighborhood Hits	227
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

SLIT2_MOUSE
θ value	0.000158464 (rank : 109)	NC score	0.301799 (rank : 229)
Query Neighborhood Hits	362	Target Neighborhood Hits	684	Shared Neighborhood Hits	197
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

WISP1_MOUSE
θ value	0.00020696 (rank : 110)	NC score	0.293833 (rank : 236)
Query Neighborhood Hits	362	Target Neighborhood Hits	123	Shared Neighborhood Hits	80
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

IBP3_MOUSE
θ value	0.000270298 (rank : 111)	NC score	0.149503 (rank : 374)
Query Neighborhood Hits	362	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

IBP7_HUMAN
θ value	0.000270298 (rank : 112)	NC score	0.168484 (rank : 346)
Query Neighborhood Hits	362	Target Neighborhood Hits	220	Shared Neighborhood Hits	42
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

LAMC1_MOUSE
θ value	0.000270298 (rank : 113)	NC score	0.401714 (rank : 136)
Query Neighborhood Hits	362	Target Neighborhood Hits	856	Shared Neighborhood Hits	200
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

PGBM_MOUSE
θ value	0.000270298 (rank : 114)	NC score	0.290403 (rank : 238)
Query Neighborhood Hits	362	Target Neighborhood Hits	1073	Shared Neighborhood Hits	218
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

LTB1L_MOUSE
θ value	0.00035302 (rank : 115)	NC score	0.421559 (rank : 115)
Query Neighborhood Hits	362	Target Neighborhood Hits	514	Shared Neighborhood Hits	195
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	0.00035302 (rank : 116)	NC score	0.420231 (rank : 118)
Query Neighborhood Hits	362	Target Neighborhood Hits	479	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NOV_MOUSE
θ value	0.000461057 (rank : 117)	NC score	0.282439 (rank : 250)
Query Neighborhood Hits	362	Target Neighborhood Hits	130	Shared Neighborhood Hits	83
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

ESM1_MOUSE
θ value	0.000786445 (rank : 118)	NC score	0.301662 (rank : 230)
Query Neighborhood Hits	362	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LDLR_MOUSE
θ value	0.000786445 (rank : 119)	NC score	0.310421 (rank : 220)
Query Neighborhood Hits	362	Target Neighborhood Hits	382	Shared Neighborhood Hits	168
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

DLL1_MOUSE
θ value	0.00102713 (rank : 120)	NC score	0.451904 (rank : 79)
Query Neighborhood Hits	362	Target Neighborhood Hits	456	Shared Neighborhood Hits	212
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

CYR61_HUMAN
θ value	0.00134147 (rank : 121)	NC score	0.305432 (rank : 225)
Query Neighborhood Hits	362	Target Neighborhood Hits	159	Shared Neighborhood Hits	102
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

CYR61_MOUSE
θ value	0.00134147 (rank : 122)	NC score	0.304194 (rank : 227)
Query Neighborhood Hits	362	Target Neighborhood Hits	156	Shared Neighborhood Hits	99
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

IBP5_HUMAN
θ value	0.00134147 (rank : 123)	NC score	0.152962 (rank : 372)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

IBP5_MOUSE
θ value	0.00134147 (rank : 124)	NC score	0.153567 (rank : 369)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

KR122_HUMAN
θ value	0.00134147 (rank : 125)	NC score	0.315994 (rank : 215)
Query Neighborhood Hits	362	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

MATN2_HUMAN
θ value	0.00134147 (rank : 126)	NC score	0.360945 (rank : 164)
Query Neighborhood Hits	362	Target Neighborhood Hits	365	Shared Neighborhood Hits	146
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

WISP3_HUMAN
θ value	0.00134147 (rank : 127)	NC score	0.220155 (rank : 299)
Query Neighborhood Hits	362	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

IBP4_HUMAN
θ value	0.00175202 (rank : 128)	NC score	0.139197 (rank : 392)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

LAMA2_MOUSE
θ value	0.00175202 (rank : 129)	NC score	0.394349 (rank : 141)
Query Neighborhood Hits	362	Target Neighborhood Hits	1198	Shared Neighborhood Hits	224
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

STAB2_MOUSE
θ value	0.00175202 (rank : 130)	NC score	0.443621 (rank : 85)
Query Neighborhood Hits	362	Target Neighborhood Hits	528	Shared Neighborhood Hits	234
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

ZAN_HUMAN
θ value	0.00175202 (rank : 131)	NC score	0.376071 (rank : 157)
Query Neighborhood Hits	362	Target Neighborhood Hits	679	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

EGF_HUMAN
θ value	0.00228821 (rank : 132)	NC score	0.318749 (rank : 209)
Query Neighborhood Hits	362	Target Neighborhood Hits	343	Shared Neighborhood Hits	150
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

GRN_MOUSE
θ value	0.00228821 (rank : 133)	NC score	0.454119 (rank : 77)
Query Neighborhood Hits	362	Target Neighborhood Hits	248	Shared Neighborhood Hits	175
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

KR410_HUMAN
θ value	0.00228821 (rank : 134)	NC score	0.434609 (rank : 98)
Query Neighborhood Hits	362	Target Neighborhood Hits	156	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

PCSK5_HUMAN
θ value	0.00228821 (rank : 135)	NC score	0.261957 (rank : 280)
Query Neighborhood Hits	362	Target Neighborhood Hits	291	Shared Neighborhood Hits	151
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

DLL1_HUMAN
θ value	0.00298849 (rank : 136)	NC score	0.443105 (rank : 86)
Query Neighborhood Hits	362	Target Neighborhood Hits	455	Shared Neighborhood Hits	205
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

IBP4_MOUSE
θ value	0.00298849 (rank : 137)	NC score	0.137346 (rank : 395)
Query Neighborhood Hits	362	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

MATN3_HUMAN
θ value	0.00298849 (rank : 138)	NC score	0.282541 (rank : 249)
Query Neighborhood Hits	362	Target Neighborhood Hits	268	Shared Neighborhood Hits	113
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MEGF9_HUMAN
θ value	0.00298849 (rank : 139)	NC score	0.456942 (rank : 73)
Query Neighborhood Hits	362	Target Neighborhood Hits	557	Shared Neighborhood Hits	194
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NOV_HUMAN
θ value	0.00298849 (rank : 140)	NC score	0.316347 (rank : 213)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	87
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

SREC2_HUMAN
θ value	0.00298849 (rank : 141)	NC score	0.515820 (rank : 33)
Query Neighborhood Hits	362	Target Neighborhood Hits	645	Shared Neighborhood Hits	239
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

EGF_MOUSE
θ value	0.00390308 (rank : 142)	NC score	0.333626 (rank : 185)
Query Neighborhood Hits	362	Target Neighborhood Hits	358	Shared Neighborhood Hits	155
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

KRA42_HUMAN
θ value	0.00390308 (rank : 143)	NC score	0.409423 (rank : 130)
Query Neighborhood Hits	362	Target Neighborhood Hits	149	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

KRA99_HUMAN
θ value	0.00390308 (rank : 144)	NC score	0.383527 (rank : 147)
Query Neighborhood Hits	362	Target Neighborhood Hits	173	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KRA11_HUMAN
θ value	0.00509761 (rank : 145)	NC score	0.396212 (rank : 139)
Query Neighborhood Hits	362	Target Neighborhood Hits	155	Shared Neighborhood Hits	109
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA59_HUMAN
θ value	0.00509761 (rank : 146)	NC score	0.490289 (rank : 47)
Query Neighborhood Hits	362	Target Neighborhood Hits	310	Shared Neighborhood Hits	178
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LAMB3_HUMAN
θ value	0.00509761 (rank : 147)	NC score	0.382029 (rank : 150)
Query Neighborhood Hits	362	Target Neighborhood Hits	461	Shared Neighborhood Hits	156
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LDLR_HUMAN
θ value	0.00509761 (rank : 148)	NC score	0.320519 (rank : 204)
Query Neighborhood Hits	362	Target Neighborhood Hits	375	Shared Neighborhood Hits	170
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

NFX1_HUMAN
θ value	0.00509761 (rank : 149)	NC score	0.384988 (rank : 145)
Query Neighborhood Hits	362	Target Neighborhood Hits	405	Shared Neighborhood Hits	150
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NOTC4_MOUSE
θ value	0.00509761 (rank : 150)	NC score	0.458436 (rank : 71)
Query Neighborhood Hits	362	Target Neighborhood Hits	872	Shared Neighborhood Hits	248
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

INSR_MOUSE
θ value	0.00665767 (rank : 151)	NC score	0.032218 (rank : 702)
Query Neighborhood Hits	362	Target Neighborhood Hits	968	Shared Neighborhood Hits	74
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KRA13_HUMAN
θ value	0.00665767 (rank : 152)	NC score	0.420300 (rank : 117)
Query Neighborhood Hits	362	Target Neighborhood Hits	144	Shared Neighborhood Hits	107
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LRP8_MOUSE
θ value	0.00665767 (rank : 153)	NC score	0.298157 (rank : 233)
Query Neighborhood Hits	362	Target Neighborhood Hits	385	Shared Neighborhood Hits	160
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

SLIT1_HUMAN
θ value	0.00665767 (rank : 154)	NC score	0.313156 (rank : 217)
Query Neighborhood Hits	362	Target Neighborhood Hits	700	Shared Neighborhood Hits	197
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

SLIT2_HUMAN
θ value	0.00665767 (rank : 155)	NC score	0.308414 (rank : 222)
Query Neighborhood Hits	362	Target Neighborhood Hits	708	Shared Neighborhood Hits	209
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CTGF_HUMAN
θ value	0.00869519 (rank : 156)	NC score	0.307725 (rank : 223)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	86
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

IBP3_HUMAN
θ value	0.00869519 (rank : 157)	NC score	0.154130 (rank : 366)
Query Neighborhood Hits	362	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

MATN3_MOUSE
θ value	0.00869519 (rank : 158)	NC score	0.288331 (rank : 240)
Query Neighborhood Hits	362	Target Neighborhood Hits	261	Shared Neighborhood Hits	116
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

WISP2_MOUSE
θ value	0.00869519 (rank : 159)	NC score	0.317893 (rank : 210)
Query Neighborhood Hits	362	Target Neighborhood Hits	129	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

FBLN2_HUMAN
θ value	0.0113563 (rank : 160)	NC score	0.412068 (rank : 127)
Query Neighborhood Hits	362	Target Neighborhood Hits	392	Shared Neighborhood Hits	172
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KR413_HUMAN
θ value	0.0113563 (rank : 161)	NC score	0.331857 (rank : 188)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

KRA92_HUMAN
θ value	0.0113563 (rank : 162)	NC score	0.426652 (rank : 108)
Query Neighborhood Hits	362	Target Neighborhood Hits	198	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

LTBP3_HUMAN
θ value	0.0113563 (rank : 163)	NC score	0.427609 (rank : 104)
Query Neighborhood Hits	362	Target Neighborhood Hits	502	Shared Neighborhood Hits	205
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

PCSK6_HUMAN
θ value	0.0113563 (rank : 164)	NC score	0.231771 (rank : 294)
Query Neighborhood Hits	362	Target Neighborhood Hits	298	Shared Neighborhood Hits	132
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TINAL_MOUSE
θ value	0.0113563 (rank : 165)	NC score	0.070665 (rank : 590)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	Q99JR5, Q9EQT9	Gene names	Tinagl1, Arg1, Lcn7, Tinagl
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Androgen- regulated gene 1 protein) (Adrenocortical zonation factor 1) (AZ-1) (Tubulointerstitial nephritis antigen-related protein) (TARP).

KR511_HUMAN
θ value	0.0148317 (rank : 166)	NC score	0.466262 (rank : 66)
Query Neighborhood Hits	362	Target Neighborhood Hits	231	Shared Neighborhood Hits	142
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

LAMC2_HUMAN
θ value	0.0148317 (rank : 167)	NC score	0.380436 (rank : 153)
Query Neighborhood Hits	362	Target Neighborhood Hits	715	Shared Neighborhood Hits	186
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

NET2_HUMAN
θ value	0.0148317 (rank : 168)	NC score	0.312455 (rank : 218)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	117
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

SLIT3_HUMAN
θ value	0.0148317 (rank : 169)	NC score	0.288487 (rank : 239)
Query Neighborhood Hits	362	Target Neighborhood Hits	682	Shared Neighborhood Hits	186
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

STAB1_HUMAN
θ value	0.0148317 (rank : 170)	NC score	0.453635 (rank : 78)
Query Neighborhood Hits	362	Target Neighborhood Hits	546	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

TRBM_HUMAN
θ value	0.0148317 (rank : 171)	NC score	0.385356 (rank : 144)
Query Neighborhood Hits	362	Target Neighborhood Hits	339	Shared Neighborhood Hits	163
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

CTGF_MOUSE
θ value	0.0193708 (rank : 172)	NC score	0.285449 (rank : 245)
Query Neighborhood Hits	362	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

KRA15_HUMAN
θ value	0.0193708 (rank : 173)	NC score	0.401453 (rank : 138)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA57_HUMAN
θ value	0.0193708 (rank : 174)	NC score	0.510971 (rank : 35)
Query Neighborhood Hits	362	Target Neighborhood Hits	269	Shared Neighborhood Hits	164
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

ZC3H3_MOUSE
θ value	0.0193708 (rank : 175)	NC score	0.037764 (rank : 698)
Query Neighborhood Hits	362	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

ITB4_HUMAN
θ value	0.0252991 (rank : 176)	NC score	0.246206 (rank : 292)
Query Neighborhood Hits	362	Target Neighborhood Hits	458	Shared Neighborhood Hits	159
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KRA93_HUMAN
θ value	0.0330416 (rank : 177)	NC score	0.426138 (rank : 111)
Query Neighborhood Hits	362	Target Neighborhood Hits	203	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

SORL_MOUSE
θ value	0.0330416 (rank : 178)	NC score	0.265520 (rank : 274)
Query Neighborhood Hits	362	Target Neighborhood Hits	439	Shared Neighborhood Hits	164
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

TRBM_MOUSE
θ value	0.0330416 (rank : 179)	NC score	0.381214 (rank : 151)
Query Neighborhood Hits	362	Target Neighborhood Hits	361	Shared Neighborhood Hits	165
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

WFDC3_HUMAN
θ value	0.0330416 (rank : 180)	NC score	0.263529 (rank : 277)
Query Neighborhood Hits	362	Target Neighborhood Hits	138	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

WISP2_HUMAN
θ value	0.0330416 (rank : 181)	NC score	0.294070 (rank : 235)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

ATS18_HUMAN
θ value	0.0431538 (rank : 182)	NC score	0.061097 (rank : 643)
Query Neighborhood Hits	362	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

IBP2_MOUSE
θ value	0.0431538 (rank : 183)	NC score	0.143415 (rank : 381)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

CELR2_MOUSE
θ value	0.0563607 (rank : 184)	NC score	0.175877 (rank : 337)
Query Neighborhood Hits	362	Target Neighborhood Hits	584	Shared Neighborhood Hits	163
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

INSR_HUMAN
θ value	0.0563607 (rank : 185)	NC score	0.034093 (rank : 700)
Query Neighborhood Hits	362	Target Neighborhood Hits	963	Shared Neighborhood Hits	81
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

KRA55_HUMAN
θ value	0.0563607 (rank : 186)	NC score	0.494642 (rank : 44)
Query Neighborhood Hits	362	Target Neighborhood Hits	257	Shared Neighborhood Hits	153
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NET4_HUMAN
θ value	0.0563607 (rank : 187)	NC score	0.317223 (rank : 212)
Query Neighborhood Hits	362	Target Neighborhood Hits	191	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

STAB1_MOUSE
θ value	0.0563607 (rank : 188)	NC score	0.456168 (rank : 74)
Query Neighborhood Hits	362	Target Neighborhood Hits	566	Shared Neighborhood Hits	248
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

ADA18_MOUSE
θ value	0.0736092 (rank : 189)	NC score	0.124752 (rank : 410)
Query Neighborhood Hits	362	Target Neighborhood Hits	227	Shared Neighborhood Hits	131
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ATS12_HUMAN
θ value	0.0736092 (rank : 190)	NC score	0.065920 (rank : 619)
Query Neighborhood Hits	362	Target Neighborhood Hits	251	Shared Neighborhood Hits	62
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

CELR2_HUMAN
θ value	0.0736092 (rank : 191)	NC score	0.200110 (rank : 311)
Query Neighborhood Hits	362	Target Neighborhood Hits	657	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

KRA24_HUMAN
θ value	0.0736092 (rank : 192)	NC score	0.372469 (rank : 160)
Query Neighborhood Hits	362	Target Neighborhood Hits	192	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

AD26A_MOUSE
θ value	0.0961366 (rank : 193)	NC score	0.079313 (rank : 559)
Query Neighborhood Hits	362	Target Neighborhood Hits	165	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ADA28_MOUSE
θ value	0.0961366 (rank : 194)	NC score	0.106544 (rank : 462)
Query Neighborhood Hits	362	Target Neighborhood Hits	241	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

KR124_HUMAN
θ value	0.0961366 (rank : 195)	NC score	0.320280 (rank : 205)
Query Neighborhood Hits	362	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

KRA94_HUMAN
θ value	0.0961366 (rank : 196)	NC score	0.425888 (rank : 112)
Query Neighborhood Hits	362	Target Neighborhood Hits	204	Shared Neighborhood Hits	140
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

NET4_MOUSE
θ value	0.0961366 (rank : 197)	NC score	0.316336 (rank : 214)
Query Neighborhood Hits	362	Target Neighborhood Hits	180	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

STAB2_HUMAN
θ value	0.0961366 (rank : 198)	NC score	0.440595 (rank : 90)
Query Neighborhood Hits	362	Target Neighborhood Hits	534	Shared Neighborhood Hits	239
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

TNR9_MOUSE
θ value	0.0961366 (rank : 199)	NC score	0.135627 (rank : 396)
Query Neighborhood Hits	362	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

WIF1_MOUSE
θ value	0.0961366 (rank : 200)	NC score	0.454330 (rank : 76)
Query Neighborhood Hits	362	Target Neighborhood Hits	393	Shared Neighborhood Hits	211
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

FBLN1_HUMAN
θ value	0.125558 (rank : 201)	NC score	0.370629 (rank : 161)
Query Neighborhood Hits	362	Target Neighborhood Hits	324	Shared Neighborhood Hits	154
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

IBP1_MOUSE
θ value	0.125558 (rank : 202)	NC score	0.141521 (rank : 388)
Query Neighborhood Hits	362	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

LAMA4_HUMAN
θ value	0.125558 (rank : 203)	NC score	0.319478 (rank : 207)
Query Neighborhood Hits	362	Target Neighborhood Hits	708	Shared Neighborhood Hits	147
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LTBP3_MOUSE
θ value	0.125558 (rank : 204)	NC score	0.420222 (rank : 119)
Query Neighborhood Hits	362	Target Neighborhood Hits	475	Shared Neighborhood Hits	198
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MT2_MOUSE
θ value	0.125558 (rank : 205)	NC score	0.172435 (rank : 339)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	51
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

SLIT1_MOUSE
θ value	0.125558 (rank : 206)	NC score	0.309559 (rank : 221)
Query Neighborhood Hits	362	Target Neighborhood Hits	715	Shared Neighborhood Hits	203
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

IBP2_HUMAN
θ value	0.163984 (rank : 207)	NC score	0.140383 (rank : 389)
Query Neighborhood Hits	362	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

KR171_HUMAN
θ value	0.163984 (rank : 208)	NC score	0.406133 (rank : 132)
Query Neighborhood Hits	362	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA98_HUMAN
θ value	0.163984 (rank : 209)	NC score	0.410796 (rank : 128)
Query Neighborhood Hits	362	Target Neighborhood Hits	185	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

ADAM8_HUMAN
θ value	0.21417 (rank : 210)	NC score	0.144680 (rank : 379)
Query Neighborhood Hits	362	Target Neighborhood Hits	327	Shared Neighborhood Hits	162
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ITB7_HUMAN
θ value	0.21417 (rank : 211)	NC score	0.276827 (rank : 258)
Query Neighborhood Hits	362	Target Neighborhood Hits	290	Shared Neighborhood Hits	182
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LAMA3_HUMAN
θ value	0.21417 (rank : 212)	NC score	0.324086 (rank : 197)
Query Neighborhood Hits	362	Target Neighborhood Hits	760	Shared Neighborhood Hits	160
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

MT1M_HUMAN
θ value	0.21417 (rank : 213)	NC score	0.114732 (rank : 437)
Query Neighborhood Hits	362	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

NET2_MOUSE
θ value	0.21417 (rank : 214)	NC score	0.310803 (rank : 219)
Query Neighborhood Hits	362	Target Neighborhood Hits	193	Shared Neighborhood Hits	120
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

SPY1_HUMAN
θ value	0.21417 (rank : 215)	NC score	0.060494 (rank : 645)
Query Neighborhood Hits	362	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

CUBN_HUMAN
θ value	0.279714 (rank : 216)	NC score	0.350199 (rank : 169)
Query Neighborhood Hits	362	Target Neighborhood Hits	482	Shared Neighborhood Hits	182
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

KRA54_HUMAN
θ value	0.279714 (rank : 217)	NC score	0.509568 (rank : 36)
Query Neighborhood Hits	362	Target Neighborhood Hits	270	Shared Neighborhood Hits	155
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MT1H_HUMAN
θ value	0.279714 (rank : 218)	NC score	0.154057 (rank : 367)
Query Neighborhood Hits	362	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

ADAM7_HUMAN
θ value	0.365318 (rank : 219)	NC score	0.110177 (rank : 453)
Query Neighborhood Hits	362	Target Neighborhood Hits	221	Shared Neighborhood Hits	132
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

ADAM7_MOUSE
θ value	0.365318 (rank : 220)	NC score	0.094232 (rank : 504)
Query Neighborhood Hits	362	Target Neighborhood Hits	200	Shared Neighborhood Hits	110
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

DLK_HUMAN
θ value	0.365318 (rank : 221)	NC score	0.429970 (rank : 102)
Query Neighborhood Hits	362	Target Neighborhood Hits	401	Shared Neighborhood Hits	196
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL3_MOUSE
θ value	0.365318 (rank : 222)	NC score	0.402554 (rank : 135)
Query Neighborhood Hits	362	Target Neighborhood Hits	399	Shared Neighborhood Hits	178
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

KRA51_HUMAN
θ value	0.365318 (rank : 223)	NC score	0.516493 (rank : 32)
Query Neighborhood Hits	362	Target Neighborhood Hits	288	Shared Neighborhood Hits	165
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

LAMA4_MOUSE
θ value	0.365318 (rank : 224)	NC score	0.342175 (rank : 179)
Query Neighborhood Hits	362	Target Neighborhood Hits	584	Shared Neighborhood Hits	151
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MEGF8_MOUSE
θ value	0.365318 (rank : 225)	NC score	0.435098 (rank : 96)
Query Neighborhood Hits	362	Target Neighborhood Hits	520	Shared Neighborhood Hits	201
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

SPY1_MOUSE
θ value	0.365318 (rank : 226)	NC score	0.057752 (rank : 657)
Query Neighborhood Hits	362	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

VEGFC_HUMAN
θ value	0.365318 (rank : 227)	NC score	0.154525 (rank : 364)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	81
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

WIF1_HUMAN
θ value	0.365318 (rank : 228)	NC score	0.446710 (rank : 82)
Query Neighborhood Hits	362	Target Neighborhood Hits	392	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

EMR1_HUMAN
θ value	0.47712 (rank : 229)	NC score	0.301457 (rank : 231)
Query Neighborhood Hits	362	Target Neighborhood Hits	382	Shared Neighborhood Hits	144
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

IDD_HUMAN
θ value	0.47712 (rank : 230)	NC score	0.092359 (rank : 512)
Query Neighborhood Hits	362	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

KR123_HUMAN
θ value	0.47712 (rank : 231)	NC score	0.287755 (rank : 241)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	58
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

KR510_HUMAN
θ value	0.47712 (rank : 232)	NC score	0.467278 (rank : 65)
Query Neighborhood Hits	362	Target Neighborhood Hits	217	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA52_HUMAN
θ value	0.47712 (rank : 233)	NC score	0.482247 (rank : 56)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

LAMC2_MOUSE
θ value	0.47712 (rank : 234)	NC score	0.387079 (rank : 142)
Query Neighborhood Hits	362	Target Neighborhood Hits	614	Shared Neighborhood Hits	186
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

TENN_MOUSE
θ value	0.47712 (rank : 235)	NC score	0.230730 (rank : 295)
Query Neighborhood Hits	362	Target Neighborhood Hits	484	Shared Neighborhood Hits	190
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TINAL_HUMAN
θ value	0.47712 (rank : 236)	NC score	0.063673 (rank : 626)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZM7, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3	Gene names	TINAGL1, GIS5, LCN7, OLRG2, TINAGL
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2).

ADA25_MOUSE
θ value	0.62314 (rank : 237)	NC score	0.092996 (rank : 510)
Query Neighborhood Hits	362	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

ALK1_HUMAN
θ value	0.62314 (rank : 238)	NC score	0.056361 (rank : 665)
Query Neighborhood Hits	362	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

HTRA4_HUMAN
θ value	0.62314 (rank : 239)	NC score	0.156080 (rank : 363)
Query Neighborhood Hits	362	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

IDD_MOUSE
θ value	0.62314 (rank : 240)	NC score	0.084856 (rank : 539)
Query Neighborhood Hits	362	Target Neighborhood Hits	151	Shared Neighborhood Hits	37
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

KR121_HUMAN
θ value	0.62314 (rank : 241)	NC score	0.161447 (rank : 357)
Query Neighborhood Hits	362	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

ADA18_HUMAN
θ value	0.813845 (rank : 242)	NC score	0.105528 (rank : 467)
Query Neighborhood Hits	362	Target Neighborhood Hits	184	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

AMNLS_MOUSE
θ value	0.813845 (rank : 243)	NC score	0.045655 (rank : 693)
Query Neighborhood Hits	362	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q99JB7, Q5I0U1, Q99MP9	Gene names	Amn
Domain Architecture	No domain graphic available
Description	Amnionless protein precursor.

CUBN_MOUSE
θ value	0.813845 (rank : 244)	NC score	0.345869 (rank : 174)
Query Neighborhood Hits	362	Target Neighborhood Hits	477	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

GRN_HUMAN
θ value	0.813845 (rank : 245)	NC score	0.449134 (rank : 80)
Query Neighborhood Hits	362	Target Neighborhood Hits	268	Shared Neighborhood Hits	169
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LRP2_HUMAN
θ value	0.813845 (rank : 246)	NC score	0.319493 (rank : 206)
Query Neighborhood Hits	362	Target Neighborhood Hits	573	Shared Neighborhood Hits	221
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

RSPO2_HUMAN
θ value	0.813845 (rank : 247)	NC score	0.116358 (rank : 430)
Query Neighborhood Hits	362	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

ALK1_MOUSE
θ value	1.06291 (rank : 248)	NC score	0.048997 (rank : 692)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	P97430, O09081, O09082	Gene names	Slpi
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (Secretory leukocyte protease inhibitor).

CRUM1_MOUSE
θ value	1.06291 (rank : 249)	NC score	0.427195 (rank : 106)
Query Neighborhood Hits	362	Target Neighborhood Hits	444	Shared Neighborhood Hits	190
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

KR261_HUMAN
θ value	1.06291 (rank : 250)	NC score	0.248446 (rank : 289)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

LCE1A_HUMAN
θ value	1.06291 (rank : 251)	NC score	0.264058 (rank : 276)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

MSMB_HUMAN
θ value	1.06291 (rank : 252)	NC score	0.091911 (rank : 515)
Query Neighborhood Hits	362	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P08118, P11999, Q13125, Q9UC59	Gene names	MSMB, PRSP
Domain Architecture
Description	Beta-microseminoprotein precursor (Prostate secreted seminal plasma protein) (Prostate secretory protein PSP94) (PSP-94) (Seminal plasma beta-inhibin) (Immunoglobulin-binding factor) (IGBF) (PN44).

CT127_HUMAN
θ value	1.38821 (rank : 253)	NC score	0.143377 (rank : 382)
Query Neighborhood Hits	362	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

DLK_MOUSE
θ value	1.38821 (rank : 254)	NC score	0.423751 (rank : 113)
Query Neighborhood Hits	362	Target Neighborhood Hits	374	Shared Neighborhood Hits	188
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

EGFL9_HUMAN
θ value	1.38821 (rank : 255)	NC score	0.413512 (rank : 125)
Query Neighborhood Hits	362	Target Neighborhood Hits	365	Shared Neighborhood Hits	182
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LYAG_HUMAN
θ value	1.38821 (rank : 256)	NC score	0.011627 (rank : 711)
Query Neighborhood Hits	362	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

MCSP_MOUSE
θ value	1.38821 (rank : 257)	NC score	0.222935 (rank : 298)
Query Neighborhood Hits	362	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MT1F_HUMAN
θ value	1.38821 (rank : 258)	NC score	0.119859 (rank : 421)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

MT1G_HUMAN
θ value	1.38821 (rank : 259)	NC score	0.135530 (rank : 397)
Query Neighborhood Hits	362	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

MT1I_HUMAN
θ value	1.38821 (rank : 260)	NC score	0.107691 (rank : 461)
Query Neighborhood Hits	362	Target Neighborhood Hits	64	Shared Neighborhood Hits	41
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

MT1L_HUMAN
θ value	1.38821 (rank : 261)	NC score	0.142380 (rank : 385)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

MT1X_HUMAN
θ value	1.38821 (rank : 262)	NC score	0.176572 (rank : 335)
Query Neighborhood Hits	362	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

MT1_MOUSE
θ value	1.38821 (rank : 263)	NC score	0.162370 (rank : 356)
Query Neighborhood Hits	362	Target Neighborhood Hits	72	Shared Neighborhood Hits	49
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

MT2_HUMAN
θ value	1.38821 (rank : 264)	NC score	0.121723 (rank : 418)
Query Neighborhood Hits	362	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

MT3_MOUSE
θ value	1.38821 (rank : 265)	NC score	0.197874 (rank : 313)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	42
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

MT4_HUMAN
θ value	1.38821 (rank : 266)	NC score	0.187602 (rank : 322)
Query Neighborhood Hits	362	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

NID2_MOUSE
θ value	1.38821 (rank : 267)	NC score	0.321895 (rank : 201)
Query Neighborhood Hits	362	Target Neighborhood Hits	338	Shared Neighborhood Hits	156
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

ADA19_MOUSE
θ value	1.81305 (rank : 268)	NC score	0.118281 (rank : 423)
Query Neighborhood Hits	362	Target Neighborhood Hits	315	Shared Neighborhood Hits	133
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

FST_HUMAN
θ value	1.81305 (rank : 269)	NC score	0.142199 (rank : 386)
Query Neighborhood Hits	362	Target Neighborhood Hits	129	Shared Neighborhood Hits	65
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

FST_MOUSE
θ value	1.81305 (rank : 270)	NC score	0.163613 (rank : 354)
Query Neighborhood Hits	362	Target Neighborhood Hits	146	Shared Neighborhood Hits	79
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

HHIP_HUMAN
θ value	1.81305 (rank : 271)	NC score	0.348435 (rank : 171)
Query Neighborhood Hits	362	Target Neighborhood Hits	249	Shared Neighborhood Hits	161
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

LCE1F_HUMAN
θ value	1.81305 (rank : 272)	NC score	0.275214 (rank : 260)
Query Neighborhood Hits	362	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LRP1B_MOUSE
θ value	1.81305 (rank : 273)	NC score	0.339394 (rank : 182)
Query Neighborhood Hits	362	Target Neighborhood Hits	606	Shared Neighborhood Hits	233
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MEGF8_HUMAN
θ value	1.81305 (rank : 274)	NC score	0.441137 (rank : 89)
Query Neighborhood Hits	362	Target Neighborhood Hits	528	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MT1E_HUMAN
θ value	1.81305 (rank : 275)	NC score	0.124213 (rank : 413)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	50
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

MT4_MOUSE
θ value	1.81305 (rank : 276)	NC score	0.205392 (rank : 306)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

TNR5_MOUSE
θ value	1.81305 (rank : 277)	NC score	0.097704 (rank : 490)
Query Neighborhood Hits	362	Target Neighborhood Hits	131	Shared Neighborhood Hits	61
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

UHRF1_MOUSE
θ value	1.81305 (rank : 278)	NC score	0.008446 (rank : 717)
Query Neighborhood Hits	362	Target Neighborhood Hits	278	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ADA24_MOUSE
θ value	2.36792 (rank : 279)	NC score	0.094885 (rank : 500)
Query Neighborhood Hits	362	Target Neighborhood Hits	230	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

ATRN_MOUSE
θ value	2.36792 (rank : 280)	NC score	0.291938 (rank : 237)
Query Neighborhood Hits	362	Target Neighborhood Hits	519	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

EZH1_HUMAN
θ value	2.36792 (rank : 281)	NC score	0.041878 (rank : 697)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	2.36792 (rank : 282)	NC score	0.043146 (rank : 695)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	47
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

FSTL1_HUMAN
θ value	2.36792 (rank : 283)	NC score	0.083040 (rank : 546)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

ITB1_HUMAN
θ value	2.36792 (rank : 284)	NC score	0.266381 (rank : 273)
Query Neighborhood Hits	362	Target Neighborhood Hits	298	Shared Neighborhood Hits	183
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	2.36792 (rank : 285)	NC score	0.249802 (rank : 286)
Query Neighborhood Hits	362	Target Neighborhood Hits	282	Shared Neighborhood Hits	167
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KCNC3_MOUSE
θ value	2.36792 (rank : 286)	NC score	0.002326 (rank : 726)
Query Neighborhood Hits	362	Target Neighborhood Hits	173	Shared Neighborhood Hits	2
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

LCE1C_HUMAN
θ value	2.36792 (rank : 287)	NC score	0.301228 (rank : 232)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1E_HUMAN
θ value	2.36792 (rank : 288)	NC score	0.282191 (rank : 251)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LRP1B_HUMAN
θ value	2.36792 (rank : 289)	NC score	0.342495 (rank : 178)
Query Neighborhood Hits	362	Target Neighborhood Hits	602	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MT1B_HUMAN
θ value	2.36792 (rank : 290)	NC score	0.137962 (rank : 394)
Query Neighborhood Hits	362	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

PLXB3_MOUSE
θ value	2.36792 (rank : 291)	NC score	0.010482 (rank : 713)
Query Neighborhood Hits	362	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

RSPO2_MOUSE
θ value	2.36792 (rank : 292)	NC score	0.113864 (rank : 439)
Query Neighborhood Hits	362	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

SORL_HUMAN
θ value	2.36792 (rank : 293)	NC score	0.247712 (rank : 291)
Query Neighborhood Hits	362	Target Neighborhood Hits	440	Shared Neighborhood Hits	159
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TRAF1_MOUSE
θ value	2.36792 (rank : 294)	NC score	0.017556 (rank : 708)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	8
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

ZN597_HUMAN
θ value	2.36792 (rank : 295)	NC score	-0.010467 (rank : 727)
Query Neighborhood Hits	362	Target Neighborhood Hits	722	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LX8	Gene names	ZNF597
Domain Architecture	No domain graphic available
Description	Zinc finger protein 597.

ADA19_HUMAN
θ value	3.0926 (rank : 296)	NC score	0.113371 (rank : 444)
Query Neighborhood Hits	362	Target Neighborhood Hits	381	Shared Neighborhood Hits	124
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

ADA21_HUMAN
θ value	3.0926 (rank : 297)	NC score	0.087913 (rank : 528)
Query Neighborhood Hits	362	Target Neighborhood Hits	181	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

ADA22_HUMAN
θ value	3.0926 (rank : 298)	NC score	0.094445 (rank : 503)
Query Neighborhood Hits	362	Target Neighborhood Hits	211	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADAM8_MOUSE
θ value	3.0926 (rank : 299)	NC score	0.147014 (rank : 377)
Query Neighborhood Hits	362	Target Neighborhood Hits	326	Shared Neighborhood Hits	154
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

EPHB3_HUMAN
θ value	3.0926 (rank : 300)	NC score	0.004710 (rank : 723)
Query Neighborhood Hits	362	Target Neighborhood Hits	996	Shared Neighborhood Hits	43
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

KR133_HUMAN
θ value	3.0926 (rank : 301)	NC score	0.154455 (rank : 365)
Query Neighborhood Hits	362	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

RFX5_HUMAN
θ value	3.0926 (rank : 302)	NC score	0.017622 (rank : 707)
Query Neighborhood Hits	362	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

TNR1A_HUMAN
θ value	3.0926 (rank : 303)	NC score	0.056506 (rank : 663)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

TNR4_HUMAN
θ value	3.0926 (rank : 304)	NC score	0.120193 (rank : 420)
Query Neighborhood Hits	362	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

AT11A_MOUSE
θ value	4.03905 (rank : 305)	NC score	0.002405 (rank : 725)
Query Neighborhood Hits	362	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

CELR1_MOUSE
θ value	4.03905 (rank : 306)	NC score	0.176037 (rank : 336)
Query Neighborhood Hits	362	Target Neighborhood Hits	617	Shared Neighborhood Hits	163
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

EGFL9_MOUSE
θ value	4.03905 (rank : 307)	NC score	0.410034 (rank : 129)
Query Neighborhood Hits	362	Target Neighborhood Hits	379	Shared Neighborhood Hits	185
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FBLN1_MOUSE
θ value	4.03905 (rank : 308)	NC score	0.368440 (rank : 162)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	156
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

IBP1_HUMAN
θ value	4.03905 (rank : 309)	NC score	0.121165 (rank : 419)
Query Neighborhood Hits	362	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

IL9_MOUSE
θ value	4.03905 (rank : 310)	NC score	0.025400 (rank : 706)
Query Neighborhood Hits	362	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P15247	Gene names	Il9
Domain Architecture
Description	Interleukin-9 precursor (IL-9) (T-cell growth factor P40) (P40 cytokine).

LCE1D_HUMAN
θ value	4.03905 (rank : 311)	NC score	0.252285 (rank : 283)
Query Neighborhood Hits	362	Target Neighborhood Hits	44	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LRP8_HUMAN
θ value	4.03905 (rank : 312)	NC score	0.270266 (rank : 268)
Query Neighborhood Hits	362	Target Neighborhood Hits	346	Shared Neighborhood Hits	143
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

MT1A_HUMAN
θ value	4.03905 (rank : 313)	NC score	0.153218 (rank : 370)
Query Neighborhood Hits	362	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

SPR2B_MOUSE
θ value	4.03905 (rank : 314)	NC score	0.106461 (rank : 464)
Query Neighborhood Hits	362	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

THYG_HUMAN
θ value	4.03905 (rank : 315)	NC score	0.042825 (rank : 696)
Query Neighborhood Hits	362	Target Neighborhood Hits	154	Shared Neighborhood Hits	51
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

TNR1B_HUMAN
θ value	4.03905 (rank : 316)	NC score	0.062566 (rank : 634)
Query Neighborhood Hits	362	Target Neighborhood Hits	127	Shared Neighborhood Hits	51
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

VEGFD_HUMAN
θ value	4.03905 (rank : 317)	NC score	0.031281 (rank : 703)
Query Neighborhood Hits	362	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

CREL1_MOUSE
θ value	5.27518 (rank : 318)	NC score	0.414078 (rank : 124)
Query Neighborhood Hits	362	Target Neighborhood Hits	524	Shared Neighborhood Hits	189
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

FA9_HUMAN
θ value	5.27518 (rank : 319)	NC score	0.096450 (rank : 497)
Query Neighborhood Hits	362	Target Neighborhood Hits	421	Shared Neighborhood Hits	106
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FSTL1_MOUSE
θ value	5.27518 (rank : 320)	NC score	0.078145 (rank : 564)
Query Neighborhood Hits	362	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

LAMB3_MOUSE
θ value	5.27518 (rank : 321)	NC score	0.407636 (rank : 131)
Query Neighborhood Hits	362	Target Neighborhood Hits	444	Shared Neighborhood Hits	172
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LIGA_MOUSE
θ value	5.27518 (rank : 322)	NC score	0.011750 (rank : 709)
Query Neighborhood Hits	362	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q61211, Q3TDE0, Q3THV5, Q3TTP4, Q8C491, Q8CBF1, Q8CC17, Q8R1I9, Q8R3M5	Gene names	Lgtn
Domain Architecture	No domain graphic available
Description	Ligatin.

LRP1_HUMAN
θ value	5.27518 (rank : 323)	NC score	0.350962 (rank : 168)
Query Neighborhood Hits	362	Target Neighborhood Hits	617	Shared Neighborhood Hits	235
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

SEM5B_MOUSE
θ value	5.27518 (rank : 324)	NC score	0.061100 (rank : 642)
Query Neighborhood Hits	362	Target Neighborhood Hits	190	Shared Neighborhood Hits	48
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

TNR4_MOUSE
θ value	5.27518 (rank : 325)	NC score	0.124785 (rank : 409)
Query Neighborhood Hits	362	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

TRAF1_HUMAN
θ value	5.27518 (rank : 326)	NC score	0.011699 (rank : 710)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

UBP54_HUMAN
θ value	5.27518 (rank : 327)	NC score	0.008426 (rank : 718)
Query Neighborhood Hits	362	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

V2R1B_MOUSE
θ value	5.27518 (rank : 328)	NC score	0.004749 (rank : 722)
Query Neighborhood Hits	362	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

ZN502_HUMAN
θ value	5.27518 (rank : 329)	NC score	-0.010806 (rank : 728)
Query Neighborhood Hits	362	Target Neighborhood Hits	762	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TBZ5	Gene names	ZNF502
Domain Architecture	No domain graphic available
Description	Zinc finger protein 502.

ADA12_MOUSE
θ value	6.88961 (rank : 330)	NC score	0.091966 (rank : 514)
Query Neighborhood Hits	362	Target Neighborhood Hits	474	Shared Neighborhood Hits	100
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA22_MOUSE
θ value	6.88961 (rank : 331)	NC score	0.099870 (rank : 484)
Query Neighborhood Hits	362	Target Neighborhood Hits	225	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

ADAM9_MOUSE
θ value	6.88961 (rank : 332)	NC score	0.117992 (rank : 424)
Query Neighborhood Hits	362	Target Neighborhood Hits	325	Shared Neighborhood Hits	149
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

ATRN_HUMAN
θ value	6.88961 (rank : 333)	NC score	0.287734 (rank : 242)
Query Neighborhood Hits	362	Target Neighborhood Hits	525	Shared Neighborhood Hits	180
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

FURIN_HUMAN
θ value	6.88961 (rank : 334)	NC score	0.061086 (rank : 644)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

ITB6_HUMAN
θ value	6.88961 (rank : 335)	NC score	0.271604 (rank : 266)
Query Neighborhood Hits	362	Target Neighborhood Hits	318	Shared Neighborhood Hits	190
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

JHD1A_MOUSE
θ value	6.88961 (rank : 336)	NC score	0.007680 (rank : 719)
Query Neighborhood Hits	362	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

KIME_MOUSE
θ value	6.88961 (rank : 337)	NC score	0.010413 (rank : 714)
Query Neighborhood Hits	362	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R008	Gene names	Mvk
Domain Architecture
Description	Mevalonate kinase (EC 2.7.1.36) (MK).

LCE1B_HUMAN
θ value	6.88961 (rank : 338)	NC score	0.285175 (rank : 246)
Query Neighborhood Hits	362	Target Neighborhood Hits	58	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LRP3_HUMAN
θ value	6.88961 (rank : 339)	NC score	0.090346 (rank : 518)
Query Neighborhood Hits	362	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MATN2_MOUSE
θ value	6.88961 (rank : 340)	NC score	0.346626 (rank : 173)
Query Neighborhood Hits	362	Target Neighborhood Hits	356	Shared Neighborhood Hits	146
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

RP1L1_MOUSE
θ value	6.88961 (rank : 341)	NC score	0.008987 (rank : 716)
Query Neighborhood Hits	362	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SEM5B_HUMAN
θ value	6.88961 (rank : 342)	NC score	0.058029 (rank : 655)
Query Neighborhood Hits	362	Target Neighborhood Hits	178	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

SLIT3_MOUSE
θ value	6.88961 (rank : 343)	NC score	0.304727 (rank : 226)
Query Neighborhood Hits	362	Target Neighborhood Hits	700	Shared Neighborhood Hits	207
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

TNR14_HUMAN
θ value	6.88961 (rank : 344)	NC score	0.123578 (rank : 414)
Query Neighborhood Hits	362	Target Neighborhood Hits	149	Shared Neighborhood Hits	74
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

TNR18_MOUSE
θ value	6.88961 (rank : 345)	NC score	0.026837 (rank : 705)
Query Neighborhood Hits	362	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

UROM_HUMAN
θ value	6.88961 (rank : 346)	NC score	0.331012 (rank : 189)
Query Neighborhood Hits	362	Target Neighborhood Hits	284	Shared Neighborhood Hits	136
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VLDLR_HUMAN
θ value	6.88961 (rank : 347)	NC score	0.304121 (rank : 228)
Query Neighborhood Hits	362	Target Neighborhood Hits	383	Shared Neighborhood Hits	171
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.294551 (rank : 234)
Query Neighborhood Hits	362	Target Neighborhood Hits	360	Shared Neighborhood Hits	158
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

ADA15_HUMAN
θ value	8.99809 (rank : 349)	NC score	0.128261 (rank : 405)
Query Neighborhood Hits	362	Target Neighborhood Hits	288	Shared Neighborhood Hits	152
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

DPOLZ_HUMAN
θ value	8.99809 (rank : 350)	NC score	0.003656 (rank : 724)
Query Neighborhood Hits	362	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

EPHA2_MOUSE
θ value	8.99809 (rank : 351)	NC score	0.011592 (rank : 712)
Query Neighborhood Hits	362	Target Neighborhood Hits	1020	Shared Neighborhood Hits	66
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

EZH2_HUMAN
θ value	8.99809 (rank : 352)	NC score	0.030425 (rank : 704)
Query Neighborhood Hits	362	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	8.99809 (rank : 353)	NC score	0.032381 (rank : 701)
Query Neighborhood Hits	362	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

HGFA_HUMAN
θ value	8.99809 (rank : 354)	NC score	0.105204 (rank : 469)
Query Neighborhood Hits	362	Target Neighborhood Hits	436	Shared Neighborhood Hits	115
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HHIP_MOUSE
θ value	8.99809 (rank : 355)	NC score	0.306916 (rank : 224)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

JHD1A_HUMAN
θ value	8.99809 (rank : 356)	NC score	0.006766 (rank : 721)
Query Neighborhood Hits	362	Target Neighborhood Hits	133	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

MLL3_HUMAN
θ value	8.99809 (rank : 357)	NC score	0.037436 (rank : 699)
Query Neighborhood Hits	362	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	8.99809 (rank : 358)	NC score	0.044497 (rank : 694)
Query Neighborhood Hits	362	Target Neighborhood Hits	1399	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NTNG1_HUMAN
θ value	8.99809 (rank : 359)	NC score	0.339395 (rank : 181)
Query Neighborhood Hits	362	Target Neighborhood Hits	247	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PLXB3_HUMAN
θ value	8.99809 (rank : 360)	NC score	0.009005 (rank : 715)
Query Neighborhood Hits	362	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

PRG4_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.007517 (rank : 720)
Query Neighborhood Hits	362	Target Neighborhood Hits	764	Shared Neighborhood Hits	30
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SPR2D_MOUSE
θ value	8.99809 (rank : 362)	NC score	0.115681 (rank : 433)
Query Neighborhood Hits	362	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

ADA10_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.102402 (rank : 477)
Query Neighborhood Hits	362	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA10_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.103965 (rank : 474)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADA11_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.123536 (rank : 415)
Query Neighborhood Hits	362	Target Neighborhood Hits	259	Shared Neighborhood Hits	142
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA11_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.124581 (rank : 411)
Query Neighborhood Hits	362	Target Neighborhood Hits	263	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA12_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.098117 (rank : 488)
Query Neighborhood Hits	362	Target Neighborhood Hits	224	Shared Neighborhood Hits	104
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.127042 (rank : 407)
Query Neighborhood Hits	362	Target Neighborhood Hits	324	Shared Neighborhood Hits	155
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

ADA17_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.122666 (rank : 416)
Query Neighborhood Hits	362	Target Neighborhood Hits	223	Shared Neighborhood Hits	111
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ADA17_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.102294 (rank : 478)
Query Neighborhood Hits	362	Target Neighborhood Hits	201	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADA20_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.066066 (rank : 617)
Query Neighborhood Hits	362	Target Neighborhood Hits	143	Shared Neighborhood Hits	68
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

ADA21_MOUSE
θ value	θ > 10 (rank : 372)	NC score	0.087289 (rank : 533)
Query Neighborhood Hits	362	Target Neighborhood Hits	172	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

ADA23_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.116298 (rank : 431)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	118
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA23_MOUSE
θ value	θ > 10 (rank : 374)	NC score	0.111625 (rank : 452)
Query Neighborhood Hits	362	Target Neighborhood Hits	245	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADA28_HUMAN
θ value	θ > 10 (rank : 375)	NC score	0.100805 (rank : 481)
Query Neighborhood Hits	362	Target Neighborhood Hits	244	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

ADA29_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.076562 (rank : 570)
Query Neighborhood Hits	362	Target Neighborhood Hits	247	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

ADA30_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.090188 (rank : 519)
Query Neighborhood Hits	362	Target Neighborhood Hits	391	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

ADA32_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.097473 (rank : 491)
Query Neighborhood Hits	362	Target Neighborhood Hits	216	Shared Neighborhood Hits	116
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA32_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.089037 (rank : 525)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	125
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

ADA33_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.113758 (rank : 441)
Query Neighborhood Hits	362	Target Neighborhood Hits	264	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADA33_MOUSE
θ value	θ > 10 (rank : 381)	NC score	0.107770 (rank : 459)
Query Neighborhood Hits	362	Target Neighborhood Hits	231	Shared Neighborhood Hits	117
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM2_HUMAN
θ value	θ > 10 (rank : 382)	NC score	0.082229 (rank : 549)
Query Neighborhood Hits	362	Target Neighborhood Hits	175	Shared Neighborhood Hits	92
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

ADAM2_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.102183 (rank : 479)
Query Neighborhood Hits	362	Target Neighborhood Hits	209	Shared Neighborhood Hits	110
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

ADAM9_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.107767 (rank : 460)
Query Neighborhood Hits	362	Target Neighborhood Hits	243	Shared Neighborhood Hits	136
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

ADM1A_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.106156 (rank : 466)
Query Neighborhood Hits	362	Target Neighborhood Hits	230	Shared Neighborhood Hits	139
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADM1B_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.087352 (rank : 532)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

APR3_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.081044 (rank : 552)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

APR3_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.089052 (rank : 524)
Query Neighborhood Hits	362	Target Neighborhood Hits	61	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ASTN_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.071893 (rank : 585)
Query Neighborhood Hits	362	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ASTN_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.071753 (rank : 587)
Query Neighborhood Hits	362	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

ATL2_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.058934 (rank : 651)
Query Neighborhood Hits	362	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

ATL2_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.056391 (rank : 664)
Query Neighborhood Hits	362	Target Neighborhood Hits	137	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ATL3_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.055451 (rank : 673)
Query Neighborhood Hits	362	Target Neighborhood Hits	414	Shared Neighborhood Hits	58
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATS12_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.062523 (rank : 635)
Query Neighborhood Hits	362	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

ATS13_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.050503 (rank : 687)
Query Neighborhood Hits	362	Target Neighborhood Hits	238	Shared Neighborhood Hits	48
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS13_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.057128 (rank : 660)
Query Neighborhood Hits	362	Target Neighborhood Hits	227	Shared Neighborhood Hits	66
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS14_HUMAN
θ value	θ > 10 (rank : 397)	NC score	0.055940 (rank : 668)
Query Neighborhood Hits	362	Target Neighborhood Hits	382	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

ATS16_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.060309 (rank : 646)
Query Neighborhood Hits	362	Target Neighborhood Hits	208	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS16_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.057928 (rank : 656)
Query Neighborhood Hits	362	Target Neighborhood Hits	179	Shared Neighborhood Hits	58
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

ATS17_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.056286 (rank : 666)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

ATS18_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.053907 (rank : 676)
Query Neighborhood Hits	362	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

ATS19_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.050732 (rank : 685)
Query Neighborhood Hits	362	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS1_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.051156 (rank : 683)
Query Neighborhood Hits	362	Target Neighborhood Hits	158	Shared Neighborhood Hits	50
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS20_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.061942 (rank : 639)
Query Neighborhood Hits	362	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS20_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.063258 (rank : 628)
Query Neighborhood Hits	362	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

ATS3_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.050940 (rank : 684)
Query Neighborhood Hits	362	Target Neighborhood Hits	179	Shared Neighborhood Hits	54
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS6_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.050674 (rank : 686)
Query Neighborhood Hits	362	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS7_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.056812 (rank : 661)
Query Neighborhood Hits	362	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

ATS9_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.073432 (rank : 581)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

BAI1_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.068954 (rank : 602)
Query Neighborhood Hits	362	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.065927 (rank : 618)
Query Neighborhood Hits	362	Target Neighborhood Hits	340	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.062613 (rank : 633)
Query Neighborhood Hits	362	Target Neighborhood Hits	332	Shared Neighborhood Hits	38
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.063559 (rank : 627)
Query Neighborhood Hits	362	Target Neighborhood Hits	323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI3_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.068363 (rank : 607)
Query Neighborhood Hits	362	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.070314 (rank : 592)
Query Neighborhood Hits	362	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BMP1_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.093015 (rank : 509)
Query Neighborhood Hits	362	Target Neighborhood Hits	233	Shared Neighborhood Hits	77
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.094063 (rank : 505)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	78
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BTC_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.051827 (rank : 682)
Query Neighborhood Hits	362	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

C1QR1_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.351071 (rank : 167)
Query Neighborhood Hits	362	Target Neighborhood Hits	493	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1QR1_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.343480 (rank : 177)
Query Neighborhood Hits	362	Target Neighborhood Hits	342	Shared Neighborhood Hits	149
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

CD248_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.249331 (rank : 287)
Query Neighborhood Hits	362	Target Neighborhood Hits	679	Shared Neighborhood Hits	143
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD248_MOUSE
θ value	θ > 10 (rank : 422)	NC score	0.241685 (rank : 293)
Query Neighborhood Hits	362	Target Neighborhood Hits	578	Shared Neighborhood Hits	127
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD320_HUMAN
θ value	θ > 10 (rank : 423)	NC score	0.081867 (rank : 550)
Query Neighborhood Hits	362	Target Neighborhood Hits	103	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

CD97_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.271531 (rank : 267)
Query Neighborhood Hits	362	Target Neighborhood Hits	353	Shared Neighborhood Hits	133
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CD97_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.226923 (rank : 297)
Query Neighborhood Hits	362	Target Neighborhood Hits	295	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CELR1_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.177444 (rank : 334)
Query Neighborhood Hits	362	Target Neighborhood Hits	613	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_HUMAN
θ value	θ > 10 (rank : 427)	NC score	0.186774 (rank : 324)
Query Neighborhood Hits	362	Target Neighborhood Hits	680	Shared Neighborhood Hits	182
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

CELR3_MOUSE
θ value	θ > 10 (rank : 428)	NC score	0.189004 (rank : 320)
Query Neighborhood Hits	362	Target Neighborhood Hits	687	Shared Neighborhood Hits	189
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.229205 (rank : 296)
Query Neighborhood Hits	362	Target Neighborhood Hits	148	Shared Neighborhood Hits	85
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.199606 (rank : 312)
Query Neighborhood Hits	362	Target Neighborhood Hits	125	Shared Neighborhood Hits	75
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CILP2_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.050317 (rank : 689)
Query Neighborhood Hits	362	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

CLC14_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.088954 (rank : 526)
Query Neighborhood Hits	362	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.096555 (rank : 496)
Query Neighborhood Hits	362	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CNTP1_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.093990 (rank : 506)
Query Neighborhood Hits	362	Target Neighborhood Hits	196	Shared Neighborhood Hits	64
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.092438 (rank : 511)
Query Neighborhood Hits	362	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.117557 (rank : 426)
Query Neighborhood Hits	362	Target Neighborhood Hits	199	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.117553 (rank : 427)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.096930 (rank : 493)
Query Neighborhood Hits	362	Target Neighborhood Hits	195	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.106489 (rank : 463)
Query Neighborhood Hits	362	Target Neighborhood Hits	187	Shared Neighborhood Hits	73
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 440)	NC score	0.110147 (rank : 454)
Query Neighborhood Hits	362	Target Neighborhood Hits	193	Shared Neighborhood Hits	80
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO1A2_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.069597 (rank : 600)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO1A2_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.067888 (rank : 610)
Query Neighborhood Hits	362	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO2A1_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.062627 (rank : 632)
Query Neighborhood Hits	362	Target Neighborhood Hits	486	Shared Neighborhood Hits	8
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

CO5A1_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.065102 (rank : 622)
Query Neighborhood Hits	362	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.062902 (rank : 630)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CO6A1_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.054415 (rank : 675)
Query Neighborhood Hits	362	Target Neighborhood Hits	264	Shared Neighborhood Hits	13
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A1_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.052898 (rank : 680)
Query Neighborhood Hits	362	Target Neighborhood Hits	241	Shared Neighborhood Hits	12
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

CO6A3_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.060067 (rank : 648)
Query Neighborhood Hits	362	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

CO6_HUMAN
θ value	θ > 10 (rank : 449)	NC score	0.117939 (rank : 425)
Query Neighborhood Hits	362	Target Neighborhood Hits	331	Shared Neighborhood Hits	100
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CO7A1_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.079911 (rank : 556)
Query Neighborhood Hits	362	Target Neighborhood Hits	807	Shared Neighborhood Hits	34
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

CO7_HUMAN
θ value	θ > 10 (rank : 451)	NC score	0.108404 (rank : 458)
Query Neighborhood Hits	362	Target Neighborhood Hits	278	Shared Neighborhood Hits	86
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO8A_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.080717 (rank : 553)
Query Neighborhood Hits	362	Target Neighborhood Hits	200	Shared Neighborhood Hits	65
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8A_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.077176 (rank : 568)
Query Neighborhood Hits	362	Target Neighborhood Hits	182	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

CO8B_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.083591 (rank : 545)
Query Neighborhood Hits	362	Target Neighborhood Hits	199	Shared Neighborhood Hits	59
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO8B_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.100579 (rank : 482)
Query Neighborhood Hits	362	Target Neighborhood Hits	224	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

CO9_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.067606 (rank : 612)
Query Neighborhood Hits	362	Target Neighborhood Hits	147	Shared Neighborhood Hits	54
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

CO9_MOUSE
θ value	θ > 10 (rank : 457)	NC score	0.067877 (rank : 611)
Query Neighborhood Hits	362	Target Neighborhood Hits	153	Shared Neighborhood Hits	55
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

COBA1_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.061132 (rank : 641)
Query Neighborhood Hits	362	Target Neighborhood Hits	491	Shared Neighborhood Hits	20
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA1_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.062396 (rank : 636)
Query Neighborhood Hits	362	Target Neighborhood Hits	487	Shared Neighborhood Hits	19
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

COBA2_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.050260 (rank : 690)
Query Neighborhood Hits	362	Target Neighborhood Hits	408	Shared Neighborhood Hits	18
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

COCA1_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.069854 (rank : 596)
Query Neighborhood Hits	362	Target Neighborhood Hits	458	Shared Neighborhood Hits	26
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COCA1_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.071612 (rank : 588)
Query Neighborhood Hits	362	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

COEA1_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.070187 (rank : 593)
Query Neighborhood Hits	362	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

COEA1_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.068524 (rank : 605)
Query Neighborhood Hits	362	Target Neighborhood Hits	402	Shared Neighborhood Hits	23
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

COKA1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.076491 (rank : 571)
Query Neighborhood Hits	362	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

COMP_HUMAN
θ value	θ > 10 (rank : 466)	NC score	0.349410 (rank : 170)
Query Neighborhood Hits	362	Target Neighborhood Hits	258	Shared Neighborhood Hits	146
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 467)	NC score	0.359284 (rank : 165)
Query Neighborhood Hits	362	Target Neighborhood Hits	290	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CORIN_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.113786 (rank : 440)
Query Neighborhood Hits	362	Target Neighborhood Hits	453	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.096664 (rank : 495)
Query Neighborhood Hits	362	Target Neighborhood Hits	451	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CP003_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.053582 (rank : 678)
Query Neighborhood Hits	362	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

CRAC1_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.139358 (rank : 391)
Query Neighborhood Hits	362	Target Neighborhood Hits	111	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.142724 (rank : 384)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CREL1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.415907 (rank : 122)
Query Neighborhood Hits	362	Target Neighborhood Hits	441	Shared Neighborhood Hits	173
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.427077 (rank : 107)
Query Neighborhood Hits	362	Target Neighborhood Hits	457	Shared Neighborhood Hits	196
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.426381 (rank : 110)
Query Neighborhood Hits	362	Target Neighborhood Hits	453	Shared Neighborhood Hits	193
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.203461 (rank : 309)
Query Neighborhood Hits	362	Target Neighborhood Hits	681	Shared Neighborhood Hits	133
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.208079 (rank : 301)
Query Neighborhood Hits	362	Target Neighborhood Hits	711	Shared Neighborhood Hits	138
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 478)	NC score	0.207406 (rank : 303)
Query Neighborhood Hits	362	Target Neighborhood Hits	676	Shared Neighborhood Hits	137
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 479)	NC score	0.205084 (rank : 307)
Query Neighborhood Hits	362	Target Neighborhood Hits	657	Shared Neighborhood Hits	137
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG4_HUMAN
θ value	θ > 10 (rank : 480)	NC score	0.098561 (rank : 487)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
θ value	θ > 10 (rank : 481)	NC score	0.094708 (rank : 501)
Query Neighborhood Hits	362	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

DKK3_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.060299 (rank : 647)
Query Neighborhood Hits	362	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

DKK3_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.063674 (rank : 625)
Query Neighborhood Hits	362	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

DLL3_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.419974 (rank : 120)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	196
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.438639 (rank : 92)
Query Neighborhood Hits	362	Target Neighborhood Hits	435	Shared Neighborhood Hits	200
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.443667 (rank : 84)
Query Neighborhood Hits	362	Target Neighborhood Hits	440	Shared Neighborhood Hits	208
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.433984 (rank : 99)
Query Neighborhood Hits	362	Target Neighborhood Hits	460	Shared Neighborhood Hits	201
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.423698 (rank : 114)
Query Neighborhood Hits	362	Target Neighborhood Hits	413	Shared Neighborhood Hits	187
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.257442 (rank : 282)
Query Neighborhood Hits	362	Target Neighborhood Hits	292	Shared Neighborhood Hits	129
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 490)	NC score	0.268289 (rank : 270)
Query Neighborhood Hits	362	Target Neighborhood Hits	317	Shared Neighborhood Hits	141
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.319001 (rank : 208)
Query Neighborhood Hits	362	Target Neighborhood Hits	325	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.314225 (rank : 216)
Query Neighborhood Hits	362	Target Neighborhood Hits	287	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.284923 (rank : 247)
Query Neighborhood Hits	362	Target Neighborhood Hits	270	Shared Neighborhood Hits	120
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.275635 (rank : 259)
Query Neighborhood Hits	362	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

ELTD1_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.159689 (rank : 361)
Query Neighborhood Hits	362	Target Neighborhood Hits	269	Shared Neighborhood Hits	99
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.215199 (rank : 300)
Query Neighborhood Hits	362	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_MOUSE
θ value	θ > 10 (rank : 497)	NC score	0.272442 (rank : 263)
Query Neighborhood Hits	362	Target Neighborhood Hits	349	Shared Neighborhood Hits	127
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.273535 (rank : 261)
Query Neighborhood Hits	362	Target Neighborhood Hits	345	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.106192 (rank : 465)
Query Neighborhood Hits	362	Target Neighborhood Hits	245	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 500)	NC score	0.078353 (rank : 563)
Query Neighborhood Hits	362	Target Neighborhood Hits	191	Shared Neighborhood Hits	58
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

EREG_HUMAN
θ value	θ > 10 (rank : 501)	NC score	0.068308 (rank : 608)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

FA10_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.096719 (rank : 494)
Query Neighborhood Hits	362	Target Neighborhood Hits	431	Shared Neighborhood Hits	112
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.099634 (rank : 485)
Query Neighborhood Hits	362	Target Neighborhood Hits	435	Shared Neighborhood Hits	116
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA12_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.095625 (rank : 499)
Query Neighborhood Hits	362	Target Neighborhood Hits	425	Shared Neighborhood Hits	108
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.087517 (rank : 531)
Query Neighborhood Hits	362	Target Neighborhood Hits	404	Shared Neighborhood Hits	108
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 506)	NC score	0.067454 (rank : 613)
Query Neighborhood Hits	362	Target Neighborhood Hits	374	Shared Neighborhood Hits	88
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FAT2_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.109810 (rank : 456)
Query Neighborhood Hits	362	Target Neighborhood Hits	507	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 508)	NC score	0.185140 (rank : 325)
Query Neighborhood Hits	362	Target Neighborhood Hits	570	Shared Neighborhood Hits	158
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FBLN3_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.329486 (rank : 192)
Query Neighborhood Hits	362	Target Neighborhood Hits	293	Shared Neighborhood Hits	134
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN3_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.317725 (rank : 211)
Query Neighborhood Hits	362	Target Neighborhood Hits	279	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN4_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.336761 (rank : 184)
Query Neighborhood Hits	362	Target Neighborhood Hits	278	Shared Neighborhood Hits	131
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.333037 (rank : 187)
Query Neighborhood Hits	362	Target Neighborhood Hits	270	Shared Neighborhood Hits	127
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.344350 (rank : 176)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

FBLN5_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.340358 (rank : 180)
Query Neighborhood Hits	362	Target Neighborhood Hits	317	Shared Neighborhood Hits	144
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FINC_HUMAN
θ value	θ > 10 (rank : 515)	NC score	0.074564 (rank : 579)
Query Neighborhood Hits	362	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

FINC_MOUSE
θ value	θ > 10 (rank : 516)	NC score	0.077947 (rank : 565)
Query Neighborhood Hits	362	Target Neighborhood Hits	309	Shared Neighborhood Hits	43
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

FREM1_HUMAN
θ value	θ > 10 (rank : 517)	NC score	0.076420 (rank : 572)
Query Neighborhood Hits	362	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	θ > 10 (rank : 518)	NC score	0.073303 (rank : 583)
Query Neighborhood Hits	362	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM2_HUMAN
θ value	θ > 10 (rank : 519)	NC score	0.096263 (rank : 498)
Query Neighborhood Hits	362	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	θ > 10 (rank : 520)	NC score	0.097910 (rank : 489)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	θ > 10 (rank : 521)	NC score	0.084697 (rank : 541)
Query Neighborhood Hits	362	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	θ > 10 (rank : 522)	NC score	0.084796 (rank : 540)
Query Neighborhood Hits	362	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FSTL3_HUMAN
θ value	θ > 10 (rank : 523)	NC score	0.170167 (rank : 343)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	99
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FSTL3_MOUSE
θ value	θ > 10 (rank : 524)	NC score	0.177695 (rank : 333)
Query Neighborhood Hits	362	Target Neighborhood Hits	152	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

FURIN_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.061757 (rank : 640)
Query Neighborhood Hits	362	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

GAS6_HUMAN
θ value	θ > 10 (rank : 526)	NC score	0.320821 (rank : 202)
Query Neighborhood Hits	362	Target Neighborhood Hits	348	Shared Neighborhood Hits	153
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GAS6_MOUSE
θ value	θ > 10 (rank : 527)	NC score	0.323684 (rank : 198)
Query Neighborhood Hits	362	Target Neighborhood Hits	343	Shared Neighborhood Hits	154
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GNPTA_HUMAN
θ value	θ > 10 (rank : 528)	NC score	0.055709 (rank : 671)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_MOUSE
θ value	θ > 10 (rank : 529)	NC score	0.054451 (rank : 674)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

HABP2_HUMAN
θ value	θ > 10 (rank : 530)	NC score	0.142004 (rank : 387)
Query Neighborhood Hits	362	Target Neighborhood Hits	431	Shared Neighborhood Hits	136
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 531)	NC score	0.140001 (rank : 390)
Query Neighborhood Hits	362	Target Neighborhood Hits	445	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HGFA_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.101534 (rank : 480)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HMCN1_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.247972 (rank : 290)
Query Neighborhood Hits	362	Target Neighborhood Hits	983	Shared Neighborhood Hits	184
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

HTRA2_HUMAN
θ value	θ > 10 (rank : 534)	NC score	0.079124 (rank : 561)
Query Neighborhood Hits	362	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

HTRA2_MOUSE
θ value	θ > 10 (rank : 535)	NC score	0.079366 (rank : 558)
Query Neighborhood Hits	362	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

IBP6_HUMAN
θ value	θ > 10 (rank : 536)	NC score	0.085879 (rank : 535)
Query Neighborhood Hits	362	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

IBP6_MOUSE
θ value	θ > 10 (rank : 537)	NC score	0.087697 (rank : 530)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

ITB1_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.249818 (rank : 285)
Query Neighborhood Hits	362	Target Neighborhood Hits	283	Shared Neighborhood Hits	171
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 539)	NC score	0.280798 (rank : 253)
Query Neighborhood Hits	362	Target Neighborhood Hits	326	Shared Neighborhood Hits	193
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 540)	NC score	0.269632 (rank : 269)
Query Neighborhood Hits	362	Target Neighborhood Hits	325	Shared Neighborhood Hits	191
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 541)	NC score	0.258410 (rank : 281)
Query Neighborhood Hits	362	Target Neighborhood Hits	319	Shared Neighborhood Hits	182
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 542)	NC score	0.267842 (rank : 272)
Query Neighborhood Hits	362	Target Neighborhood Hits	310	Shared Neighborhood Hits	184
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 543)	NC score	0.281123 (rank : 252)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	194
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.279129 (rank : 255)
Query Neighborhood Hits	362	Target Neighborhood Hits	341	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 545)	NC score	0.262150 (rank : 278)
Query Neighborhood Hits	362	Target Neighborhood Hits	277	Shared Neighborhood Hits	178
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 546)	NC score	0.207591 (rank : 302)
Query Neighborhood Hits	362	Target Neighborhood Hits	280	Shared Neighborhood Hits	169
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR111_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.264298 (rank : 275)
Query Neighborhood Hits	362	Target Neighborhood Hits	90	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

KR131_HUMAN
θ value	θ > 10 (rank : 548)	NC score	0.184709 (rank : 327)
Query Neighborhood Hits	362	Target Neighborhood Hits	123	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

KR132_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.153912 (rank : 368)
Query Neighborhood Hits	362	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

KR134_HUMAN
θ value	θ > 10 (rank : 550)	NC score	0.160547 (rank : 358)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

KR151_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.058117 (rank : 654)
Query Neighborhood Hits	362	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q3LI76	Gene names	KRTAP15-1, KAP15.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 15-1.

KR241_HUMAN
θ value	θ > 10 (rank : 552)	NC score	0.143255 (rank : 383)
Query Neighborhood Hits	362	Target Neighborhood Hits	71	Shared Neighborhood Hits	53
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

KRA32_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.084652 (rank : 542)
Query Neighborhood Hits	362	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

KRA33_HUMAN
θ value	θ > 10 (rank : 554)	NC score	0.082236 (rank : 548)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

KRA56_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.427551 (rank : 105)
Query Neighborhood Hits	362	Target Neighborhood Hits	207	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 556)	NC score	0.167577 (rank : 348)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE2B_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.148020 (rank : 375)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

LCE2C_HUMAN
θ value	θ > 10 (rank : 558)	NC score	0.171030 (rank : 340)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE2D_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.173963 (rank : 338)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

LCE3A_HUMAN
θ value	θ > 10 (rank : 560)	NC score	0.164794 (rank : 352)
Query Neighborhood Hits	362	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3B_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.109167 (rank : 457)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE4A_HUMAN
θ value	θ > 10 (rank : 562)	NC score	0.170455 (rank : 341)
Query Neighborhood Hits	362	Target Neighborhood Hits	26	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.160433 (rank : 360)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LORI_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.093277 (rank : 507)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

LRP10_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.085814 (rank : 536)
Query Neighborhood Hits	362	Target Neighborhood Hits	197	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.087835 (rank : 529)
Query Neighborhood Hits	362	Target Neighborhood Hits	169	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.063068 (rank : 629)
Query Neighborhood Hits	362	Target Neighborhood Hits	205	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.058890 (rank : 652)
Query Neighborhood Hits	362	Target Neighborhood Hits	180	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP4_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.250139 (rank : 284)
Query Neighborhood Hits	362	Target Neighborhood Hits	355	Shared Neighborhood Hits	149
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 570)	NC score	0.249185 (rank : 288)
Query Neighborhood Hits	362	Target Neighborhood Hits	351	Shared Neighborhood Hits	147
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 571)	NC score	0.105161 (rank : 470)
Query Neighborhood Hits	362	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 572)	NC score	0.111858 (rank : 449)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 573)	NC score	0.113565 (rank : 442)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	85
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 574)	NC score	0.112310 (rank : 448)
Query Neighborhood Hits	362	Target Neighborhood Hits	232	Shared Neighborhood Hits	83
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LYAM1_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.129087 (rank : 404)
Query Neighborhood Hits	362	Target Neighborhood Hits	315	Shared Neighborhood Hits	102
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.134609 (rank : 399)
Query Neighborhood Hits	362	Target Neighborhood Hits	332	Shared Neighborhood Hits	112
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.160499 (rank : 359)
Query Neighborhood Hits	362	Target Neighborhood Hits	394	Shared Neighborhood Hits	124
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 578)	NC score	0.168879 (rank : 345)
Query Neighborhood Hits	362	Target Neighborhood Hits	420	Shared Neighborhood Hits	141
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.170159 (rank : 344)
Query Neighborhood Hits	362	Target Neighborhood Hits	378	Shared Neighborhood Hits	130
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.193425 (rank : 316)
Query Neighborhood Hits	362	Target Neighborhood Hits	390	Shared Neighborhood Hits	131
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN1_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.113366 (rank : 445)
Query Neighborhood Hits	362	Target Neighborhood Hits	191	Shared Neighborhood Hits	66
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 582)	NC score	0.115307 (rank : 436)
Query Neighborhood Hits	362	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN4_HUMAN
θ value	θ > 10 (rank : 583)	NC score	0.271620 (rank : 265)
Query Neighborhood Hits	362	Target Neighborhood Hits	287	Shared Neighborhood Hits	125
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 584)	NC score	0.262001 (rank : 279)
Query Neighborhood Hits	362	Target Neighborhood Hits	277	Shared Neighborhood Hits	124
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MCSP_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.056508 (rank : 662)
Query Neighborhood Hits	362	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEP1A_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.071303 (rank : 589)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.074732 (rank : 577)
Query Neighborhood Hits	362	Target Neighborhood Hits	166	Shared Neighborhood Hits	67
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MFGM_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.071850 (rank : 586)
Query Neighborhood Hits	362	Target Neighborhood Hits	150	Shared Neighborhood Hits	60
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 589)	NC score	0.181438 (rank : 330)
Query Neighborhood Hits	362	Target Neighborhood Hits	233	Shared Neighborhood Hits	103
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

MKS3_HUMAN
θ value	θ > 10 (rank : 590)	NC score	0.104481 (rank : 472)
Query Neighborhood Hits	362	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

MKS3_MOUSE
θ value	θ > 10 (rank : 591)	NC score	0.117180 (rank : 428)
Query Neighborhood Hits	362	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

MMRN1_HUMAN
θ value	θ > 10 (rank : 592)	NC score	0.093146 (rank : 508)
Query Neighborhood Hits	362	Target Neighborhood Hits	636	Shared Neighborhood Hits	73
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

MT3_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.164762 (rank : 353)
Query Neighborhood Hits	362	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

MUC13_HUMAN
θ value	θ > 10 (rank : 594)	NC score	0.090581 (rank : 517)
Query Neighborhood Hits	362	Target Neighborhood Hits	164	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

MUC13_MOUSE
θ value	θ > 10 (rank : 595)	NC score	0.144433 (rank : 380)
Query Neighborhood Hits	362	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC1_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.053147 (rank : 679)
Query Neighborhood Hits	362	Target Neighborhood Hits	975	Shared Neighborhood Hits	26
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NAGPA_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.362374 (rank : 163)
Query Neighborhood Hits	362	Target Neighborhood Hits	282	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.375875 (rank : 158)
Query Neighborhood Hits	362	Target Neighborhood Hits	308	Shared Neighborhood Hits	186
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NET1_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.285718 (rank : 244)
Query Neighborhood Hits	362	Target Neighborhood Hits	149	Shared Neighborhood Hits	96
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

NET1_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.278423 (rank : 257)
Query Neighborhood Hits	362	Target Neighborhood Hits	151	Shared Neighborhood Hits	94
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

NEU1_MOUSE
θ value	θ > 10 (rank : 601)	NC score	0.061972 (rank : 638)
Query Neighborhood Hits	362	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

NID1_HUMAN
θ value	θ > 10 (rank : 602)	NC score	0.330597 (rank : 190)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	160
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
θ value	θ > 10 (rank : 603)	NC score	0.327260 (rank : 194)
Query Neighborhood Hits	362	Target Neighborhood Hits	335	Shared Neighborhood Hits	156
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
θ value	θ > 10 (rank : 604)	NC score	0.329867 (rank : 191)
Query Neighborhood Hits	362	Target Neighborhood Hits	456	Shared Neighborhood Hits	167
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NRG1_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.082932 (rank : 547)
Query Neighborhood Hits	362	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.073548 (rank : 580)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	56
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.085631 (rank : 537)
Query Neighborhood Hits	362	Target Neighborhood Hits	392	Shared Neighborhood Hits	64
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.079578 (rank : 557)
Query Neighborhood Hits	362	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.069778 (rank : 597)
Query Neighborhood Hits	362	Target Neighborhood Hits	79	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRX1A_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.132346 (rank : 401)
Query Neighborhood Hits	362	Target Neighborhood Hits	170	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.130882 (rank : 402)
Query Neighborhood Hits	362	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX2A_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.135482 (rank : 398)
Query Neighborhood Hits	362	Target Neighborhood Hits	614	Shared Neighborhood Hits	83
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX3A_HUMAN
θ value	θ > 10 (rank : 613)	NC score	0.127780 (rank : 406)
Query Neighborhood Hits	362	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

NTNG1_MOUSE
θ value	θ > 10 (rank : 614)	NC score	0.333226 (rank : 186)
Query Neighborhood Hits	362	Target Neighborhood Hits	246	Shared Neighborhood Hits	123
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_HUMAN
θ value	θ > 10 (rank : 615)	NC score	0.353276 (rank : 166)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	137
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 616)	NC score	0.348340 (rank : 172)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	142
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

ODFP_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.057528 (rank : 658)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PAPPA_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.084549 (rank : 543)
Query Neighborhood Hits	362	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.066953 (rank : 614)
Query Neighborhood Hits	362	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PCSK4_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.057329 (rank : 659)
Query Neighborhood Hits	362	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

PERT_HUMAN
θ value	θ > 10 (rank : 621)	NC score	0.122440 (rank : 417)
Query Neighborhood Hits	362	Target Neighborhood Hits	221	Shared Neighborhood Hits	77
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 622)	NC score	0.117000 (rank : 429)
Query Neighborhood Hits	362	Target Neighborhood Hits	221	Shared Neighborhood Hits	76
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGCA_HUMAN
θ value	θ > 10 (rank : 623)	NC score	0.111682 (rank : 451)
Query Neighborhood Hits	362	Target Neighborhood Hits	821	Shared Neighborhood Hits	105
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.092309 (rank : 513)
Query Neighborhood Hits	362	Target Neighborhood Hits	478	Shared Neighborhood Hits	93
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGCB_MOUSE
θ value	θ > 10 (rank : 625)	NC score	0.103441 (rank : 475)
Query Neighborhood Hits	362	Target Neighborhood Hits	459	Shared Neighborhood Hits	95
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PGH1_HUMAN
θ value	θ > 10 (rank : 626)	NC score	0.058456 (rank : 653)
Query Neighborhood Hits	362	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH1_MOUSE
θ value	θ > 10 (rank : 627)	NC score	0.070323 (rank : 591)
Query Neighborhood Hits	362	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PGH2_HUMAN
θ value	θ > 10 (rank : 628)	NC score	0.075170 (rank : 574)
Query Neighborhood Hits	362	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

PGH2_MOUSE
θ value	θ > 10 (rank : 629)	NC score	0.077600 (rank : 567)
Query Neighborhood Hits	362	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

PROC_HUMAN
θ value	θ > 10 (rank : 630)	NC score	0.086059 (rank : 534)
Query Neighborhood Hits	362	Target Neighborhood Hits	406	Shared Neighborhood Hits	114
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 631)	NC score	0.099355 (rank : 486)
Query Neighborhood Hits	362	Target Neighborhood Hits	426	Shared Neighborhood Hits	122
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROP_HUMAN
θ value	θ > 10 (rank : 632)	NC score	0.090926 (rank : 516)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

PROP_MOUSE
θ value	θ > 10 (rank : 633)	NC score	0.104419 (rank : 473)
Query Neighborhood Hits	362	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

PROS_HUMAN
θ value	θ > 10 (rank : 634)	NC score	0.320562 (rank : 203)
Query Neighborhood Hits	362	Target Neighborhood Hits	340	Shared Neighborhood Hits	157
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_MOUSE
θ value	θ > 10 (rank : 635)	NC score	0.323368 (rank : 199)
Query Neighborhood Hits	362	Target Neighborhood Hits	330	Shared Neighborhood Hits	153
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROZ_HUMAN
θ value	θ > 10 (rank : 636)	NC score	0.192634 (rank : 317)
Query Neighborhood Hits	362	Target Neighborhood Hits	422	Shared Neighborhood Hits	121
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

PROZ_MOUSE
θ value	θ > 10 (rank : 637)	NC score	0.190296 (rank : 319)
Query Neighborhood Hits	362	Target Neighborhood Hits	410	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

RELN_HUMAN
θ value	θ > 10 (rank : 638)	NC score	0.110141 (rank : 455)
Query Neighborhood Hits	362	Target Neighborhood Hits	233	Shared Neighborhood Hits	102
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

RELN_MOUSE
θ value	θ > 10 (rank : 639)	NC score	0.114545 (rank : 438)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	105
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RSPO1_HUMAN
θ value	θ > 10 (rank : 640)	NC score	0.094592 (rank : 502)
Query Neighborhood Hits	362	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

RSPO1_MOUSE
θ value	θ > 10 (rank : 641)	NC score	0.079077 (rank : 562)
Query Neighborhood Hits	362	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

RSPO3_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.138166 (rank : 393)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.125272 (rank : 408)
Query Neighborhood Hits	362	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.124457 (rank : 412)
Query Neighborhood Hits	362	Target Neighborhood Hits	110	Shared Neighborhood Hits	56
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 645)	NC score	0.113416 (rank : 443)
Query Neighborhood Hits	362	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

SCUB3_HUMAN
θ value	θ > 10 (rank : 646)	NC score	0.380737 (rank : 152)
Query Neighborhood Hits	362	Target Neighborhood Hits	428	Shared Neighborhood Hits	176
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 647)	NC score	0.382421 (rank : 149)
Query Neighborhood Hits	362	Target Neighborhood Hits	442	Shared Neighborhood Hits	180
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEM5A_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.059119 (rank : 650)
Query Neighborhood Hits	362	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SEM5A_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.050376 (rank : 688)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	32
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

SHBG_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.062846 (rank : 631)
Query Neighborhood Hits	362	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

SHBG_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.059506 (rank : 649)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SMDF_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.084202 (rank : 544)
Query Neighborhood Hits	362	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SPON1_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.088143 (rank : 527)
Query Neighborhood Hits	362	Target Neighborhood Hits	117	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

SPON1_MOUSE
θ value	θ > 10 (rank : 654)	NC score	0.089994 (rank : 520)
Query Neighborhood Hits	362	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

SPR2E_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.055889 (rank : 669)
Query Neighborhood Hits	362	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

SPR2E_MOUSE
θ value	θ > 10 (rank : 656)	NC score	0.077613 (rank : 566)
Query Neighborhood Hits	362	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_HUMAN
θ value	θ > 10 (rank : 657)	NC score	0.074818 (rank : 576)
Query Neighborhood Hits	362	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

SPR2F_MOUSE
θ value	θ > 10 (rank : 658)	NC score	0.074604 (rank : 578)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2G_MOUSE
θ value	θ > 10 (rank : 659)	NC score	0.103001 (rank : 476)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

SPR2H_MOUSE
θ value	θ > 10 (rank : 660)	NC score	0.075528 (rank : 573)
Query Neighborhood Hits	362	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

SPR2I_MOUSE
θ value	θ > 10 (rank : 661)	NC score	0.076990 (rank : 569)
Query Neighborhood Hits	362	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ST14_HUMAN
θ value	θ > 10 (rank : 662)	NC score	0.068761 (rank : 603)
Query Neighborhood Hits	362	Target Neighborhood Hits	409	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 663)	NC score	0.070126 (rank : 594)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	116
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

SUSD1_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.285918 (rank : 243)
Query Neighborhood Hits	362	Target Neighborhood Hits	285	Shared Neighborhood Hits	111
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD2_HUMAN
θ value	θ > 10 (rank : 665)	NC score	0.063899 (rank : 624)
Query Neighborhood Hits	362	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	θ > 10 (rank : 666)	NC score	0.066805 (rank : 615)
Query Neighborhood Hits	362	Target Neighborhood Hits	104	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 667)	NC score	0.166291 (rank : 350)
Query Neighborhood Hits	362	Target Neighborhood Hits	132	Shared Neighborhood Hits	69
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 668)	NC score	0.200396 (rank : 310)
Query Neighborhood Hits	362	Target Neighborhood Hits	146	Shared Neighborhood Hits	83
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 669)	NC score	0.166358 (rank : 349)
Query Neighborhood Hits	362	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.273470 (rank : 262)
Query Neighborhood Hits	362	Target Neighborhood Hits	239	Shared Neighborhood Hits	134
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.280469 (rank : 254)
Query Neighborhood Hits	362	Target Neighborhood Hits	244	Shared Neighborhood Hits	136
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.184774 (rank : 326)
Query Neighborhood Hits	362	Target Neighborhood Hits	211	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.188236 (rank : 321)
Query Neighborhood Hits	362	Target Neighborhood Hits	214	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENN_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.206358 (rank : 305)
Query Neighborhood Hits	362	Target Neighborhood Hits	453	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 675)	NC score	0.268096 (rank : 271)
Query Neighborhood Hits	362	Target Neighborhood Hits	526	Shared Neighborhood Hits	195
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 676)	NC score	0.271976 (rank : 264)
Query Neighborhood Hits	362	Target Neighborhood Hits	531	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TIE1_HUMAN
θ value	θ > 10 (rank : 677)	NC score	0.115323 (rank : 435)
Query Neighborhood Hits	362	Target Neighborhood Hits	1241	Shared Neighborhood Hits	173
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	θ > 10 (rank : 678)	NC score	0.111789 (rank : 450)
Query Neighborhood Hits	362	Target Neighborhood Hits	1266	Shared Neighborhood Hits	176
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE2_HUMAN
θ value	θ > 10 (rank : 679)	NC score	0.097124 (rank : 492)
Query Neighborhood Hits	362	Target Neighborhood Hits	1192	Shared Neighborhood Hits	151
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 680)	NC score	0.099981 (rank : 483)
Query Neighborhood Hits	362	Target Neighborhood Hits	1204	Shared Neighborhood Hits	154
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

TINAG_HUMAN
θ value	θ > 10 (rank : 681)	NC score	0.069616 (rank : 598)
Query Neighborhood Hits	362	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

TLL1_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.089093 (rank : 523)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	76
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.089268 (rank : 522)
Query Neighborhood Hits	362	Target Neighborhood Hits	237	Shared Neighborhood Hits	77
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.089551 (rank : 521)
Query Neighborhood Hits	362	Target Neighborhood Hits	241	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.085103 (rank : 538)
Query Neighborhood Hits	362	Target Neighborhood Hits	240	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TNR11_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.080032 (rank : 555)
Query Neighborhood Hits	362	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

TNR11_MOUSE
θ value	θ > 10 (rank : 687)	NC score	0.070025 (rank : 595)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

TNR16_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.156191 (rank : 362)
Query Neighborhood Hits	362	Target Neighborhood Hits	183	Shared Neighborhood Hits	89
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

TNR16_MOUSE
θ value	θ > 10 (rank : 689)	NC score	0.147830 (rank : 376)
Query Neighborhood Hits	362	Target Neighborhood Hits	178	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

TNR18_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.050130 (rank : 691)
Query Neighborhood Hits	362	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

TNR19_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.080425 (rank : 554)
Query Neighborhood Hits	362	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR19_MOUSE
θ value	θ > 10 (rank : 692)	NC score	0.069479 (rank : 601)
Query Neighborhood Hits	362	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR1A_MOUSE
θ value	θ > 10 (rank : 693)	NC score	0.051952 (rank : 681)
Query Neighborhood Hits	362	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

TNR21_MOUSE
θ value	θ > 10 (rank : 694)	NC score	0.053867 (rank : 677)
Query Neighborhood Hits	362	Target Neighborhood Hits	108	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

TNR22_MOUSE
θ value	θ > 10 (rank : 695)	NC score	0.079254 (rank : 560)
Query Neighborhood Hits	362	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

TNR23_MOUSE
θ value	θ > 10 (rank : 696)	NC score	0.104533 (rank : 471)
Query Neighborhood Hits	362	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

TNR25_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.145369 (rank : 378)
Query Neighborhood Hits	362	Target Neighborhood Hits	172	Shared Neighborhood Hits	69
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

TNR26_MOUSE
θ value	θ > 10 (rank : 698)	NC score	0.072463 (rank : 584)
Query Neighborhood Hits	362	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

TNR3_HUMAN
θ value	θ > 10 (rank : 699)	NC score	0.065474 (rank : 621)
Query Neighborhood Hits	362	Target Neighborhood Hits	145	Shared Neighborhood Hits	47
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

TNR3_MOUSE
θ value	θ > 10 (rank : 700)	NC score	0.073381 (rank : 582)
Query Neighborhood Hits	362	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

TNR5_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.066071 (rank : 616)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

TNR6B_HUMAN
θ value	θ > 10 (rank : 702)	NC score	0.068753 (rank : 604)
Query Neighborhood Hits	362	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

TNR6_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.056002 (rank : 667)
Query Neighborhood Hits	362	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR6_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.068394 (rank : 606)
Query Neighborhood Hits	362	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

TNR7_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.112559 (rank : 446)
Query Neighborhood Hits	362	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR7_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.081169 (rank : 551)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

TNR8_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.112438 (rank : 447)
Query Neighborhood Hits	362	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

TNR8_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.115866 (rank : 432)
Query Neighborhood Hits	362	Target Neighborhood Hits	208	Shared Neighborhood Hits	70
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TNR9_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.119828 (rank : 422)
Query Neighborhood Hits	362	Target Neighborhood Hits	166	Shared Neighborhood Hits	86
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

TR10B_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.055877 (rank : 670)
Query Neighborhood Hits	362	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

TRI42_MOUSE
θ value	θ > 10 (rank : 711)	NC score	0.074987 (rank : 575)
Query Neighborhood Hits	362	Target Neighborhood Hits	316	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TSEAR_HUMAN
θ value	θ > 10 (rank : 712)	NC score	0.064127 (rank : 623)
Query Neighborhood Hits	362	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WU66	Gene names	TSPEAR, C21orf29
Domain Architecture
Description	Protein TSPEAR precursor (TSP-EAR).

TSP3_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.322461 (rank : 200)
Query Neighborhood Hits	362	Target Neighborhood Hits	250	Shared Neighborhood Hits	129
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 714)	NC score	0.325795 (rank : 195)
Query Neighborhood Hits	362	Target Neighborhood Hits	247	Shared Neighborhood Hits	134
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.337920 (rank : 183)
Query Neighborhood Hits	362	Target Neighborhood Hits	277	Shared Neighborhood Hits	144
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 716)	NC score	0.345796 (rank : 175)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.115672 (rank : 434)
Query Neighborhood Hits	362	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.133261 (rank : 400)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_MOUSE
θ value	θ > 10 (rank : 719)	NC score	0.328653 (rank : 193)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	136
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

VASN_HUMAN
θ value	θ > 10 (rank : 720)	NC score	0.065585 (rank : 620)
Query Neighborhood Hits	362	Target Neighborhood Hits	449	Shared Neighborhood Hits	78
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VASN_MOUSE
θ value	θ > 10 (rank : 721)	NC score	0.062371 (rank : 637)
Query Neighborhood Hits	362	Target Neighborhood Hits	426	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

VEGFC_MOUSE
θ value	θ > 10 (rank : 722)	NC score	0.129424 (rank : 403)
Query Neighborhood Hits	362	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

WFDC2_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.105478 (rank : 468)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

WFDC5_HUMAN
θ value	θ > 10 (rank : 724)	NC score	0.055483 (rank : 672)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

ZN330_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.069615 (rank : 599)
Query Neighborhood Hits	362	Target Neighborhood Hits	83	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZN330_MOUSE
θ value	θ > 10 (rank : 726)	NC score	0.068180 (rank : 609)
Query Neighborhood Hits	362	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

ZNFX1_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.204267 (rank : 308)
Query Neighborhood Hits	362	Target Neighborhood Hits	308	Shared Neighborhood Hits	109
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.196789 (rank : 314)
Query Neighborhood Hits	362	Target Neighborhood Hits	407	Shared Neighborhood Hits	123
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

Hits sorted by NC score

CRIM1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	362	Target Neighborhood Hits	362	Shared Neighborhood Hits	362
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

BMPER_MOUSE
NC score	0.670515 (rank : 2)	θ value	1.08979e-29 (rank : 6)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	152
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

BMPER_HUMAN
NC score	0.648596 (rank : 3)	θ value	1.16434e-31 (rank : 5)
Query Neighborhood Hits	362	Target Neighborhood Hits	175	Shared Neighborhood Hits	131
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

FRAS1_HUMAN
NC score	0.623302 (rank : 4)	θ value	2.26708e-35 (rank : 4)
Query Neighborhood Hits	362	Target Neighborhood Hits	759	Shared Neighborhood Hits	271
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR104_HUMAN
NC score	0.622755 (rank : 5)	θ value	4.76016e-09 (rank : 39)
Query Neighborhood Hits	362	Target Neighborhood Hits	313	Shared Neighborhood Hits	188
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

FRAS1_MOUSE
NC score	0.621033 (rank : 6)	θ value	1.85459e-37 (rank : 2)
Query Neighborhood Hits	362	Target Neighborhood Hits	747	Shared Neighborhood Hits	269
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ZAN_MOUSE
NC score	0.618361 (rank : 7)	θ value	1.13037e-18 (rank : 13)
Query Neighborhood Hits	362	Target Neighborhood Hits	808	Shared Neighborhood Hits	291
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KR106_HUMAN
NC score	0.617930 (rank : 8)	θ value	2.13673e-09 (rank : 37)
Query Neighborhood Hits	362	Target Neighborhood Hits	347	Shared Neighborhood Hits	209
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
NC score	0.611028 (rank : 9)	θ value	3.08544e-08 (rank : 45)
Query Neighborhood Hits	362	Target Neighborhood Hits	330	Shared Neighborhood Hits	200
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

NELL1_HUMAN
NC score	0.598281 (rank : 10)	θ value	1.73584e-35 (rank : 3)
Query Neighborhood Hits	362	Target Neighborhood Hits	451	Shared Neighborhood Hits	226
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

CRDL2_MOUSE
NC score	0.577406 (rank : 11)	θ value	4.58923e-20 (rank : 9)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	76
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

NELL2_MOUSE
NC score	0.574861 (rank : 12)	θ value	8.63488e-27 (rank : 7)
Query Neighborhood Hits	362	Target Neighborhood Hits	436	Shared Neighborhood Hits	219
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

KR105_HUMAN
NC score	0.573114 (rank : 13)	θ value	3.41135e-07 (rank : 63)
Query Neighborhood Hits	362	Target Neighborhood Hits	271	Shared Neighborhood Hits	176
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

NELL2_HUMAN
NC score	0.569386 (rank : 14)	θ value	1.24688e-25 (rank : 8)
Query Neighborhood Hits	362	Target Neighborhood Hits	449	Shared Neighborhood Hits	216
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

KRA53_HUMAN
NC score	0.565935 (rank : 15)	θ value	3.77169e-06 (rank : 84)
Query Neighborhood Hits	362	Target Neighborhood Hits	331	Shared Neighborhood Hits	199
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

SREC_HUMAN
NC score	0.564006 (rank : 16)	θ value	7.1131e-05 (rank : 101)
Query Neighborhood Hits	362	Target Neighborhood Hits	645	Shared Neighborhood Hits	258
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

CRDL2_HUMAN
NC score	0.562565 (rank : 17)	θ value	8.65492e-19 (rank : 12)
Query Neighborhood Hits	362	Target Neighborhood Hits	99	Shared Neighborhood Hits	72
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

KR101_HUMAN
NC score	0.549537 (rank : 18)	θ value	3.41135e-07 (rank : 62)
Query Neighborhood Hits	362	Target Neighborhood Hits	261	Shared Neighborhood Hits	161
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR10B_HUMAN
NC score	0.548153 (rank : 19)	θ value	8.97725e-08 (rank : 53)
Query Neighborhood Hits	362	Target Neighborhood Hits	269	Shared Neighborhood Hits	174
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KRA58_HUMAN
NC score	0.546937 (rank : 20)	θ value	0.000121331 (rank : 105)
Query Neighborhood Hits	362	Target Neighborhood Hits	324	Shared Neighborhood Hits	190
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

CRDL1_MOUSE
NC score	0.543014 (rank : 21)	θ value	1.02238e-19 (rank : 10)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_HUMAN
NC score	0.541795 (rank : 22)	θ value	2.97466e-19 (rank : 11)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	65
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

MEGF6_HUMAN
NC score	0.538340 (rank : 23)	θ value	3.41135e-07 (rank : 65)
Query Neighborhood Hits	362	Target Neighborhood Hits	671	Shared Neighborhood Hits	283
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KR109_HUMAN
NC score	0.531962 (rank : 24)	θ value	1.29631e-06 (rank : 75)
Query Neighborhood Hits	362	Target Neighborhood Hits	226	Shared Neighborhood Hits	163
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR108_HUMAN
NC score	0.527628 (rank : 25)	θ value	1.99992e-07 (rank : 59)
Query Neighborhood Hits	362	Target Neighborhood Hits	226	Shared Neighborhood Hits	153
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR102_HUMAN
NC score	0.524968 (rank : 26)	θ value	3.19293e-05 (rank : 95)
Query Neighborhood Hits	362	Target Neighborhood Hits	264	Shared Neighborhood Hits	169
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

JAG1_HUMAN
NC score	0.522737 (rank : 27)	θ value	1.33837e-11 (rank : 26)
Query Neighborhood Hits	362	Target Neighborhood Hits	514	Shared Neighborhood Hits	238
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

CHRD_HUMAN
NC score	0.522581 (rank : 28)	θ value	2.35696e-16 (rank : 14)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	76
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

JAG1_MOUSE
NC score	0.520736 (rank : 29)	θ value	1.58096e-12 (rank : 23)
Query Neighborhood Hits	362	Target Neighborhood Hits	518	Shared Neighborhood Hits	235
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

SREC2_MOUSE
NC score	0.519030 (rank : 30)	θ value	4.1701e-05 (rank : 98)
Query Neighborhood Hits	362	Target Neighborhood Hits	605	Shared Neighborhood Hits	242
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

VWF_HUMAN
NC score	0.517597 (rank : 31)	θ value	1.99529e-15 (rank : 18)
Query Neighborhood Hits	362	Target Neighborhood Hits	396	Shared Neighborhood Hits	202
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA51_HUMAN
NC score	0.516493 (rank : 32)	θ value	0.365318 (rank : 223)
Query Neighborhood Hits	362	Target Neighborhood Hits	288	Shared Neighborhood Hits	165
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

SREC2_HUMAN
NC score	0.515820 (rank : 33)	θ value	0.00298849 (rank : 141)
Query Neighborhood Hits	362	Target Neighborhood Hits	645	Shared Neighborhood Hits	239
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CHRD_MOUSE
NC score	0.515128 (rank : 34)	θ value	1.99529e-15 (rank : 17)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

KRA57_HUMAN
NC score	0.510971 (rank : 35)	θ value	0.0193708 (rank : 174)
Query Neighborhood Hits	362	Target Neighborhood Hits	269	Shared Neighborhood Hits	164
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA54_HUMAN
NC score	0.509568 (rank : 36)	θ value	0.279714 (rank : 217)
Query Neighborhood Hits	362	Target Neighborhood Hits	270	Shared Neighborhood Hits	155
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA45_HUMAN
NC score	0.507470 (rank : 37)	θ value	3.08544e-08 (rank : 46)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	137
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

JAG2_HUMAN
NC score	0.507194 (rank : 38)	θ value	4.30538e-10 (rank : 35)
Query Neighborhood Hits	362	Target Neighborhood Hits	491	Shared Neighborhood Hits	226
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

KR10A_HUMAN
NC score	0.505129 (rank : 39)	θ value	4.1701e-05 (rank : 97)
Query Neighborhood Hits	362	Target Neighborhood Hits	232	Shared Neighborhood Hits	161
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

JAG2_MOUSE
NC score	0.503858 (rank : 40)	θ value	8.38298e-14 (rank : 19)
Query Neighborhood Hits	362	Target Neighborhood Hits	504	Shared Neighborhood Hits	232
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KRA47_HUMAN
NC score	0.502901 (rank : 41)	θ value	1.69304e-06 (rank : 78)
Query Neighborhood Hits	362	Target Neighborhood Hits	204	Shared Neighborhood Hits	148
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KR10C_HUMAN
NC score	0.502341 (rank : 42)	θ value	3.77169e-06 (rank : 83)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	148
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

MUC5B_HUMAN
NC score	0.500519 (rank : 43)	θ value	5.26297e-08 (rank : 50)
Query Neighborhood Hits	362	Target Neighborhood Hits	1020	Shared Neighborhood Hits	235
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

KRA55_HUMAN
NC score	0.494642 (rank : 44)	θ value	0.0563607 (rank : 186)
Query Neighborhood Hits	362	Target Neighborhood Hits	257	Shared Neighborhood Hits	153
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NOTC1_MOUSE
NC score	0.493952 (rank : 45)	θ value	9.26847e-13 (rank : 22)
Query Neighborhood Hits	362	Target Neighborhood Hits	916	Shared Neighborhood Hits	249
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

VWF_MOUSE
NC score	0.490874 (rank : 46)	θ value	4.02038e-16 (rank : 15)
Query Neighborhood Hits	362	Target Neighborhood Hits	381	Shared Neighborhood Hits	204
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

KRA59_HUMAN
NC score	0.490289 (rank : 47)	θ value	0.00509761 (rank : 146)
Query Neighborhood Hits	362	Target Neighborhood Hits	310	Shared Neighborhood Hits	178
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

FBN2_HUMAN
NC score	0.489216 (rank : 48)	θ value	5.26297e-08 (rank : 49)
Query Neighborhood Hits	362	Target Neighborhood Hits	560	Shared Neighborhood Hits	238
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.487480 (rank : 49)	θ value	1.06045e-08 (rank : 42)
Query Neighborhood Hits	362	Target Neighborhood Hits	563	Shared Neighborhood Hits	232
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.487179 (rank : 50)	θ value	8.11959e-09 (rank : 41)
Query Neighborhood Hits	362	Target Neighborhood Hits	557	Shared Neighborhood Hits	230
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.486346 (rank : 51)	θ value	8.97725e-08 (rank : 52)
Query Neighborhood Hits	362	Target Neighborhood Hits	549	Shared Neighborhood Hits	237
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

KR412_HUMAN
NC score	0.485288 (rank : 52)	θ value	1.17247e-07 (rank : 56)
Query Neighborhood Hits	362	Target Neighborhood Hits	178	Shared Neighborhood Hits	131
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

NOTC3_HUMAN
NC score	0.484732 (rank : 53)	θ value	3.52202e-12 (rank : 24)
Query Neighborhood Hits	362	Target Neighborhood Hits	1062	Shared Neighborhood Hits	255
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

FBN3_HUMAN
NC score	0.483812 (rank : 54)	θ value	7.84624e-12 (rank : 25)
Query Neighborhood Hits	362	Target Neighborhood Hits	543	Shared Neighborhood Hits	226
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

SSPO_MOUSE
NC score	0.483440 (rank : 55)	θ value	2.43908e-13 (rank : 21)
Query Neighborhood Hits	362	Target Neighborhood Hits	800	Shared Neighborhood Hits	287
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KRA52_HUMAN
NC score	0.482247 (rank : 56)	θ value	0.47712 (rank : 233)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	152
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KR103_HUMAN
NC score	0.482195 (rank : 57)	θ value	2.21117e-06 (rank : 81)
Query Neighborhood Hits	362	Target Neighborhood Hits	212	Shared Neighborhood Hits	155
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

LAMA5_MOUSE
NC score	0.481394 (rank : 58)	θ value	3.41135e-07 (rank : 64)
Query Neighborhood Hits	362	Target Neighborhood Hits	828	Shared Neighborhood Hits	256
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC1_HUMAN
NC score	0.480740 (rank : 59)	θ value	8.38298e-14 (rank : 20)
Query Neighborhood Hits	362	Target Neighborhood Hits	906	Shared Neighborhood Hits	245
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_MOUSE
NC score	0.479802 (rank : 60)	θ value	4.0297e-08 (rank : 48)
Query Neighborhood Hits	362	Target Neighborhood Hits	975	Shared Neighborhood Hits	247
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

AGRIN_HUMAN
NC score	0.478374 (rank : 61)	θ value	0.000158464 (rank : 108)
Query Neighborhood Hits	362	Target Neighborhood Hits	582	Shared Neighborhood Hits	227
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

KR414_HUMAN
NC score	0.477596 (rank : 62)	θ value	9.92553e-07 (rank : 72)
Query Neighborhood Hits	362	Target Neighborhood Hits	199	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LAMA5_HUMAN
NC score	0.474564 (rank : 63)	θ value	1.99992e-07 (rank : 60)
Query Neighborhood Hits	362	Target Neighborhood Hits	976	Shared Neighborhood Hits	242
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NOTC2_MOUSE
NC score	0.467945 (rank : 64)	θ value	6.21693e-09 (rank : 40)
Query Neighborhood Hits	362	Target Neighborhood Hits	1069	Shared Neighborhood Hits	249
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR510_HUMAN
NC score	0.467278 (rank : 65)	θ value	0.47712 (rank : 232)
Query Neighborhood Hits	362	Target Neighborhood Hits	217	Shared Neighborhood Hits	130
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
NC score	0.466262 (rank : 66)	θ value	0.0148317 (rank : 166)
Query Neighborhood Hits	362	Target Neighborhood Hits	231	Shared Neighborhood Hits	142
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

NOTC2_HUMAN
NC score	0.465605 (rank : 67)	θ value	2.61198e-07 (rank : 61)
Query Neighborhood Hits	362	Target Neighborhood Hits	1113	Shared Neighborhood Hits	260
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LTBP4_MOUSE
NC score	0.464485 (rank : 68)	θ value	1.69304e-06 (rank : 79)
Query Neighborhood Hits	362	Target Neighborhood Hits	607	Shared Neighborhood Hits	207
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NOTC4_HUMAN
NC score	0.462747 (rank : 69)	θ value	2.36244e-08 (rank : 44)
Query Neighborhood Hits	362	Target Neighborhood Hits	905	Shared Neighborhood Hits	251
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

LTBP2_HUMAN
NC score	0.459446 (rank : 70)	θ value	3.19293e-05 (rank : 96)
Query Neighborhood Hits	362	Target Neighborhood Hits	552	Shared Neighborhood Hits	216
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NOTC4_MOUSE
NC score	0.458436 (rank : 71)	θ value	0.00509761 (rank : 150)
Query Neighborhood Hits	362	Target Neighborhood Hits	872	Shared Neighborhood Hits	248
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

LTBP2_MOUSE
NC score	0.457865 (rank : 72)	θ value	6.87365e-08 (rank : 51)
Query Neighborhood Hits	362	Target Neighborhood Hits	617	Shared Neighborhood Hits	212
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MEGF9_HUMAN
NC score	0.456942 (rank : 73)	θ value	0.00298849 (rank : 139)
Query Neighborhood Hits	362	Target Neighborhood Hits	557	Shared Neighborhood Hits	194
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

STAB1_MOUSE
NC score	0.456168 (rank : 74)	θ value	0.0563607 (rank : 188)
Query Neighborhood Hits	362	Target Neighborhood Hits	566	Shared Neighborhood Hits	248
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

LAMA1_MOUSE
NC score	0.454499 (rank : 75)	θ value	3.29651e-10 (rank : 34)
Query Neighborhood Hits	362	Target Neighborhood Hits	838	Shared Neighborhood Hits	227
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

WIF1_MOUSE
NC score	0.454330 (rank : 76)	θ value	0.0961366 (rank : 200)
Query Neighborhood Hits	362	Target Neighborhood Hits	393	Shared Neighborhood Hits	211
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

GRN_MOUSE
NC score	0.454119 (rank : 77)	θ value	0.00228821 (rank : 133)
Query Neighborhood Hits	362	Target Neighborhood Hits	248	Shared Neighborhood Hits	175
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

STAB1_HUMAN
NC score	0.453635 (rank : 78)	θ value	0.0148317 (rank : 170)
Query Neighborhood Hits	362	Target Neighborhood Hits	546	Shared Neighborhood Hits	234
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

DLL1_MOUSE
NC score	0.451904 (rank : 79)	θ value	0.00102713 (rank : 120)
Query Neighborhood Hits	362	Target Neighborhood Hits	456	Shared Neighborhood Hits	212
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

GRN_HUMAN
NC score	0.449134 (rank : 80)	θ value	0.813845 (rank : 245)
Query Neighborhood Hits	362	Target Neighborhood Hits	268	Shared Neighborhood Hits	169
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LAMA1_HUMAN
NC score	0.448030 (rank : 81)	θ value	2.98157e-11 (rank : 28)
Query Neighborhood Hits	362	Target Neighborhood Hits	804	Shared Neighborhood Hits	221
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

WIF1_HUMAN
NC score	0.446710 (rank : 82)	θ value	0.365318 (rank : 228)
Query Neighborhood Hits	362	Target Neighborhood Hits	392	Shared Neighborhood Hits	214
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

LAMB2_HUMAN
NC score	0.444899 (rank : 83)	θ value	8.40245e-06 (rank : 87)
Query Neighborhood Hits	362	Target Neighborhood Hits	692	Shared Neighborhood Hits	198
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

DLL4_MOUSE
NC score	0.443667 (rank : 84)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	362	Target Neighborhood Hits	440	Shared Neighborhood Hits	208
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

STAB2_MOUSE
NC score	0.443621 (rank : 85)	θ value	0.00175202 (rank : 130)
Query Neighborhood Hits	362	Target Neighborhood Hits	528	Shared Neighborhood Hits	234
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

DLL1_HUMAN
NC score	0.443105 (rank : 86)	θ value	0.00298849 (rank : 136)
Query Neighborhood Hits	362	Target Neighborhood Hits	455	Shared Neighborhood Hits	205
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

LAMB2_MOUSE
NC score	0.442758 (rank : 87)	θ value	9.92553e-07 (rank : 73)
Query Neighborhood Hits	362	Target Neighborhood Hits	722	Shared Neighborhood Hits	202
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

KRA44_HUMAN
NC score	0.442499 (rank : 88)	θ value	1.43324e-05 (rank : 89)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

MEGF8_HUMAN
NC score	0.441137 (rank : 89)	θ value	1.81305 (rank : 274)
Query Neighborhood Hits	362	Target Neighborhood Hits	528	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STAB2_HUMAN
NC score	0.440595 (rank : 90)	θ value	0.0961366 (rank : 198)
Query Neighborhood Hits	362	Target Neighborhood Hits	534	Shared Neighborhood Hits	239
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

LAMC3_HUMAN
NC score	0.440463 (rank : 91)	θ value	1.43324e-05 (rank : 90)
Query Neighborhood Hits	362	Target Neighborhood Hits	588	Shared Neighborhood Hits	212
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

DLL4_HUMAN
NC score	0.438639 (rank : 92)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	362	Target Neighborhood Hits	435	Shared Neighborhood Hits	200
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

TENX_HUMAN
NC score	0.436563 (rank : 93)	θ value	2.98157e-11 (rank : 29)
Query Neighborhood Hits	362	Target Neighborhood Hits	789	Shared Neighborhood Hits	251
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

PCSK5_MOUSE
NC score	0.436515 (rank : 94)	θ value	3.64472e-09 (rank : 38)
Query Neighborhood Hits	362	Target Neighborhood Hits	613	Shared Neighborhood Hits	244
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

MEGF9_MOUSE
NC score	0.436264 (rank : 95)	θ value	9.92553e-07 (rank : 74)
Query Neighborhood Hits	362	Target Neighborhood Hits	896	Shared Neighborhood Hits	175
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF8_MOUSE
NC score	0.435098 (rank : 96)	θ value	0.365318 (rank : 225)
Query Neighborhood Hits	362	Target Neighborhood Hits	520	Shared Neighborhood Hits	201
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

TENA_HUMAN
NC score	0.434993 (rank : 97)	θ value	8.97725e-08 (rank : 55)
Query Neighborhood Hits	362	Target Neighborhood Hits	631	Shared Neighborhood Hits	226
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

KR410_HUMAN
NC score	0.434609 (rank : 98)	θ value	0.00228821 (rank : 134)
Query Neighborhood Hits	362	Target Neighborhood Hits	156	Shared Neighborhood Hits	121
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

DNER_HUMAN
NC score	0.433984 (rank : 99)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	362	Target Neighborhood Hits	460	Shared Neighborhood Hits	201
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

LAMC3_MOUSE
NC score	0.433409 (rank : 100)	θ value	0.000121331 (rank : 107)
Query Neighborhood Hits	362	Target Neighborhood Hits	624	Shared Neighborhood Hits	199
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LTB1L_HUMAN
NC score	0.432036 (rank : 101)	θ value	2.44474e-05 (rank : 92)
Query Neighborhood Hits	362	Target Neighborhood Hits	553	Shared Neighborhood Hits	198
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

DLK_HUMAN
NC score	0.429970 (rank : 102)	θ value	0.365318 (rank : 221)
Query Neighborhood Hits	362	Target Neighborhood Hits	401	Shared Neighborhood Hits	196
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

LTB1S_HUMAN
NC score	0.429273 (rank : 103)	θ value	2.44474e-05 (rank : 93)
Query Neighborhood Hits	362	Target Neighborhood Hits	502	Shared Neighborhood Hits	185
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
NC score	0.427609 (rank : 104)	θ value	0.0113563 (rank : 163)
Query Neighborhood Hits	362	Target Neighborhood Hits	502	Shared Neighborhood Hits	205
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

KRA56_HUMAN
NC score	0.427551 (rank : 105)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	362	Target Neighborhood Hits	207	Shared Neighborhood Hits	134
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

CRUM1_MOUSE
NC score	0.427195 (rank : 106)	θ value	1.06291 (rank : 249)
Query Neighborhood Hits	362	Target Neighborhood Hits	444	Shared Neighborhood Hits	190
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM1_HUMAN
NC score	0.427077 (rank : 107)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	362	Target Neighborhood Hits	457	Shared Neighborhood Hits	196
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

KRA92_HUMAN
NC score	0.426652 (rank : 108)	θ value	0.0113563 (rank : 162)
Query Neighborhood Hits	362	Target Neighborhood Hits	198	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

TENA_MOUSE
NC score	0.426534 (rank : 109)	θ value	1.17247e-07 (rank : 57)
Query Neighborhood Hits	362	Target Neighborhood Hits	596	Shared Neighborhood Hits	228
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

CRUM2_HUMAN
NC score	0.426381 (rank : 110)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	362	Target Neighborhood Hits	453	Shared Neighborhood Hits	193
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

KRA93_HUMAN
NC score	0.426138 (rank : 111)	θ value	0.0330416 (rank : 177)
Query Neighborhood Hits	362	Target Neighborhood Hits	203	Shared Neighborhood Hits	132
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
NC score	0.425888 (rank : 112)	θ value	0.0961366 (rank : 196)
Query Neighborhood Hits	362	Target Neighborhood Hits	204	Shared Neighborhood Hits	140
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

DLK_MOUSE
NC score	0.423751 (rank : 113)	θ value	1.38821 (rank : 254)
Query Neighborhood Hits	362	Target Neighborhood Hits	374	Shared Neighborhood Hits	188
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DNER_MOUSE
NC score	0.423698 (rank : 114)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	362	Target Neighborhood Hits	413	Shared Neighborhood Hits	187
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

LTB1L_MOUSE
NC score	0.421559 (rank : 115)	θ value	0.00035302 (rank : 115)
Query Neighborhood Hits	362	Target Neighborhood Hits	514	Shared Neighborhood Hits	195
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

USH2A_MOUSE
NC score	0.420965 (rank : 116)	θ value	2.98157e-11 (rank : 31)
Query Neighborhood Hits	362	Target Neighborhood Hits	626	Shared Neighborhood Hits	212
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KRA13_HUMAN
NC score	0.420300 (rank : 117)	θ value	0.00665767 (rank : 152)
Query Neighborhood Hits	362	Target Neighborhood Hits	144	Shared Neighborhood Hits	107
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

LTB1S_MOUSE
NC score	0.420231 (rank : 118)	θ value	0.00035302 (rank : 116)
Query Neighborhood Hits	362	Target Neighborhood Hits	479	Shared Neighborhood Hits	182
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_MOUSE
NC score	0.420222 (rank : 119)	θ value	0.125558 (rank : 204)
Query Neighborhood Hits	362	Target Neighborhood Hits	475	Shared Neighborhood Hits	198
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

DLL3_HUMAN
NC score	0.419974 (rank : 120)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	196
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

LAMB1_MOUSE
NC score	0.416237 (rank : 121)	θ value	8.97725e-08 (rank : 54)
Query Neighborhood Hits	362	Target Neighborhood Hits	919	Shared Neighborhood Hits	193
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

CREL1_HUMAN
NC score	0.415907 (rank : 122)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	362	Target Neighborhood Hits	441	Shared Neighborhood Hits	173
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

LAMA2_HUMAN
NC score	0.414167 (rank : 123)	θ value	3.08544e-08 (rank : 47)
Query Neighborhood Hits	362	Target Neighborhood Hits	1092	Shared Neighborhood Hits	222
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CREL1_MOUSE
NC score	0.414078 (rank : 124)	θ value	5.27518 (rank : 318)
Query Neighborhood Hits	362	Target Neighborhood Hits	524	Shared Neighborhood Hits	189
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

EGFL9_HUMAN
NC score	0.413512 (rank : 125)	θ value	1.38821 (rank : 255)
Query Neighborhood Hits	362	Target Neighborhood Hits	365	Shared Neighborhood Hits	182
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

FBLN2_MOUSE
NC score	0.413212 (rank : 126)	θ value	3.19293e-05 (rank : 94)
Query Neighborhood Hits	362	Target Neighborhood Hits	505	Shared Neighborhood Hits	179
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_HUMAN
NC score	0.412068 (rank : 127)	θ value	0.0113563 (rank : 160)
Query Neighborhood Hits	362	Target Neighborhood Hits	392	Shared Neighborhood Hits	172
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

KRA98_HUMAN
NC score	0.410796 (rank : 128)	θ value	0.163984 (rank : 209)
Query Neighborhood Hits	362	Target Neighborhood Hits	185	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

EGFL9_MOUSE
NC score	0.410034 (rank : 129)	θ value	4.03905 (rank : 307)
Query Neighborhood Hits	362	Target Neighborhood Hits	379	Shared Neighborhood Hits	185
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

KRA42_HUMAN
NC score	0.409423 (rank : 130)	θ value	0.00390308 (rank : 143)
Query Neighborhood Hits	362	Target Neighborhood Hits	149	Shared Neighborhood Hits	113
SwissProt Accessions	Q9BYR5	Gene names	KRTAP4-2, KAP4.2, KRTAP4.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-2 (Keratin-associated protein 4.2) (Ultrahigh sulfur keratin-associated protein 4.2).

LAMB3_MOUSE
NC score	0.407636 (rank : 131)	θ value	5.27518 (rank : 321)
Query Neighborhood Hits	362	Target Neighborhood Hits	444	Shared Neighborhood Hits	172
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

KR171_HUMAN
NC score	0.406133 (rank : 132)	θ value	0.163984 (rank : 208)
Query Neighborhood Hits	362	Target Neighborhood Hits	144	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

TSP1_HUMAN
NC score	0.405079 (rank : 133)	θ value	2.98157e-11 (rank : 30)
Query Neighborhood Hits	362	Target Neighborhood Hits	389	Shared Neighborhood Hits	196
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
NC score	0.403590 (rank : 134)	θ value	3.89403e-11 (rank : 32)
Query Neighborhood Hits	362	Target Neighborhood Hits	396	Shared Neighborhood Hits	196
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

DLL3_MOUSE
NC score	0.402554 (rank : 135)	θ value	0.365318 (rank : 222)
Query Neighborhood Hits	362	Target Neighborhood Hits	399	Shared Neighborhood Hits	178
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

LAMC1_MOUSE
NC score	0.401714 (rank : 136)	θ value	0.000270298 (rank : 113)
Query Neighborhood Hits	362	Target Neighborhood Hits	856	Shared Neighborhood Hits	200
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMB1_HUMAN
NC score	0.401546 (rank : 137)	θ value	6.43352e-06 (rank : 85)
Query Neighborhood Hits	362	Target Neighborhood Hits	1018	Shared Neighborhood Hits	199
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KRA15_HUMAN
NC score	0.401453 (rank : 138)	θ value	0.0193708 (rank : 173)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA11_HUMAN
NC score	0.396212 (rank : 139)	θ value	0.00509761 (rank : 145)
Query Neighborhood Hits	362	Target Neighborhood Hits	155	Shared Neighborhood Hits	109
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

LAMC1_HUMAN
NC score	0.395464 (rank : 140)	θ value	5.44631e-05 (rank : 99)
Query Neighborhood Hits	362	Target Neighborhood Hits	922	Shared Neighborhood Hits	204
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMA2_MOUSE
NC score	0.394349 (rank : 141)	θ value	0.00175202 (rank : 129)
Query Neighborhood Hits	362	Target Neighborhood Hits	1198	Shared Neighborhood Hits	224
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC2_MOUSE
NC score	0.387079 (rank : 142)	θ value	0.47712 (rank : 234)
Query Neighborhood Hits	362	Target Neighborhood Hits	614	Shared Neighborhood Hits	186
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

RECK_HUMAN
NC score	0.385842 (rank : 143)	θ value	1.29631e-06 (rank : 76)
Query Neighborhood Hits	362	Target Neighborhood Hits	189	Shared Neighborhood Hits	117
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TRBM_HUMAN
NC score	0.385356 (rank : 144)	θ value	0.0148317 (rank : 171)
Query Neighborhood Hits	362	Target Neighborhood Hits	339	Shared Neighborhood Hits	163
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NFX1_HUMAN
NC score	0.384988 (rank : 145)	θ value	0.00509761 (rank : 149)
Query Neighborhood Hits	362	Target Neighborhood Hits	405	Shared Neighborhood Hits	150
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

MUC2_HUMAN
NC score	0.384557 (rank : 146)	θ value	1.16975e-15 (rank : 16)
Query Neighborhood Hits	362	Target Neighborhood Hits	906	Shared Neighborhood Hits	156
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

KRA99_HUMAN
NC score	0.383527 (rank : 147)	θ value	0.00390308 (rank : 144)
Query Neighborhood Hits	362	Target Neighborhood Hits	173	Shared Neighborhood Hits	123
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA3_MOUSE
NC score	0.383393 (rank : 148)	θ value	0.000121331 (rank : 106)
Query Neighborhood Hits	362	Target Neighborhood Hits	859	Shared Neighborhood Hits	206
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

SCUB3_MOUSE
NC score	0.382421 (rank : 149)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	362	Target Neighborhood Hits	442	Shared Neighborhood Hits	180
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMB3_HUMAN
NC score	0.382029 (rank : 150)	θ value	0.00509761 (rank : 147)
Query Neighborhood Hits	362	Target Neighborhood Hits	461	Shared Neighborhood Hits	156
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

TRBM_MOUSE
NC score	0.381214 (rank : 151)	θ value	0.0330416 (rank : 179)
Query Neighborhood Hits	362	Target Neighborhood Hits	361	Shared Neighborhood Hits	165
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

SCUB3_HUMAN
NC score	0.380737 (rank : 152)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	362	Target Neighborhood Hits	428	Shared Neighborhood Hits	176
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LAMC2_HUMAN
NC score	0.380436 (rank : 153)	θ value	0.0148317 (rank : 167)
Query Neighborhood Hits	362	Target Neighborhood Hits	715	Shared Neighborhood Hits	186
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

TSP2_MOUSE
NC score	0.380356 (rank : 154)	θ value	1.47974e-10 (rank : 33)
Query Neighborhood Hits	362	Target Neighborhood Hits	352	Shared Neighborhood Hits	189
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

USH2A_HUMAN
NC score	0.379594 (rank : 155)	θ value	4.45536e-07 (rank : 67)
Query Neighborhood Hits	362	Target Neighborhood Hits	600	Shared Neighborhood Hits	185
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

TSP2_HUMAN
NC score	0.379302 (rank : 156)	θ value	2.28291e-11 (rank : 27)
Query Neighborhood Hits	362	Target Neighborhood Hits	359	Shared Neighborhood Hits	192
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

ZAN_HUMAN
NC score	0.376071 (rank : 157)	θ value	0.00175202 (rank : 131)
Query Neighborhood Hits	362	Target Neighborhood Hits	679	Shared Neighborhood Hits	206
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

NAGPA_MOUSE
NC score	0.375875 (rank : 158)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	362	Target Neighborhood Hits	308	Shared Neighborhood Hits	186
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

RECK_MOUSE
NC score	0.374435 (rank : 159)	θ value	1.38499e-08 (rank : 43)
Query Neighborhood Hits	362	Target Neighborhood Hits	158	Shared Neighborhood Hits	110
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

KRA24_HUMAN
NC score	0.372469 (rank : 160)	θ value	0.0736092 (rank : 192)
Query Neighborhood Hits	362	Target Neighborhood Hits	192	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

FBLN1_HUMAN
NC score	0.370629 (rank : 161)	θ value	0.125558 (rank : 201)
Query Neighborhood Hits	362	Target Neighborhood Hits	324	Shared Neighborhood Hits	154
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
NC score	0.368440 (rank : 162)	θ value	4.03905 (rank : 308)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	156
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

NAGPA_HUMAN
NC score	0.362374 (rank : 163)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	362	Target Neighborhood Hits	282	Shared Neighborhood Hits	173
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

MATN2_HUMAN
NC score	0.360945 (rank : 164)	θ value	0.00134147 (rank : 126)
Query Neighborhood Hits	362	Target Neighborhood Hits	365	Shared Neighborhood Hits	146
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

COMP_MOUSE
NC score	0.359284 (rank : 165)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	362	Target Neighborhood Hits	290	Shared Neighborhood Hits	161
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

NTNG2_HUMAN
NC score	0.353276 (rank : 166)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	137
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

C1QR1_HUMAN
NC score	0.351071 (rank : 167)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	362	Target Neighborhood Hits	493	Shared Neighborhood Hits	169
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

LRP1_HUMAN
NC score	0.350962 (rank : 168)	θ value	5.27518 (rank : 323)
Query Neighborhood Hits	362	Target Neighborhood Hits	617	Shared Neighborhood Hits	235
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

CUBN_HUMAN
NC score	0.350199 (rank : 169)	θ value	0.279714 (rank : 216)
Query Neighborhood Hits	362	Target Neighborhood Hits	482	Shared Neighborhood Hits	182
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

COMP_HUMAN
NC score	0.349410 (rank : 170)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	362	Target Neighborhood Hits	258	Shared Neighborhood Hits	146
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

HHIP_HUMAN
NC score	0.348435 (rank : 171)	θ value	1.81305 (rank : 271)
Query Neighborhood Hits	362	Target Neighborhood Hits	249	Shared Neighborhood Hits	161
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

NTNG2_MOUSE
NC score	0.348340 (rank : 172)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	142
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

MATN2_MOUSE
NC score	0.346626 (rank : 173)	θ value	6.88961 (rank : 340)
Query Neighborhood Hits	362	Target Neighborhood Hits	356	Shared Neighborhood Hits	146
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

CUBN_MOUSE
NC score	0.345869 (rank : 174)	θ value	0.813845 (rank : 244)
Query Neighborhood Hits	362	Target Neighborhood Hits	477	Shared Neighborhood Hits	172
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

TSP4_MOUSE
NC score	0.345796 (rank : 175)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

FBLN5_HUMAN
NC score	0.344350 (rank : 176)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	154
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

C1QR1_MOUSE
NC score	0.343480 (rank : 177)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	362	Target Neighborhood Hits	342	Shared Neighborhood Hits	149
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

LRP1B_HUMAN
NC score	0.342495 (rank : 178)	θ value	2.36792 (rank : 289)
Query Neighborhood Hits	362	Target Neighborhood Hits	602	Shared Neighborhood Hits	228
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LAMA4_MOUSE
NC score	0.342175 (rank : 179)	θ value	0.365318 (rank : 224)
Query Neighborhood Hits	362	Target Neighborhood Hits	584	Shared Neighborhood Hits	151
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

FBLN5_MOUSE
NC score	0.340358 (rank : 180)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	362	Target Neighborhood Hits	317	Shared Neighborhood Hits	144
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

NTNG1_HUMAN
NC score	0.339395 (rank : 181)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	362	Target Neighborhood Hits	247	Shared Neighborhood Hits	128
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

LRP1B_MOUSE
NC score	0.339394 (rank : 182)	θ value	1.81305 (rank : 273)
Query Neighborhood Hits	362	Target Neighborhood Hits	606	Shared Neighborhood Hits	233
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TSP4_HUMAN
NC score	0.337920 (rank : 183)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	362	Target Neighborhood Hits	277	Shared Neighborhood Hits	144
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

FBLN4_HUMAN
NC score	0.336761 (rank : 184)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	362	Target Neighborhood Hits	278	Shared Neighborhood Hits	131
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

EGF_MOUSE
NC score	0.333626 (rank : 185)	θ value	0.00390308 (rank : 142)
Query Neighborhood Hits	362	Target Neighborhood Hits	358	Shared Neighborhood Hits	155
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

NTNG1_MOUSE
NC score	0.333226 (rank : 186)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	362	Target Neighborhood Hits	246	Shared Neighborhood Hits	123
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

FBLN4_MOUSE
NC score	0.333037 (rank : 187)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	362	Target Neighborhood Hits	270	Shared Neighborhood Hits	127
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

KR413_HUMAN
NC score	0.331857 (rank : 188)	θ value	0.0113563 (rank : 161)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BYU7	Gene names	KRTAP4-13, KAP4.13, KRTAP4.13
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-13 (Keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.13).

UROM_HUMAN
NC score	0.331012 (rank : 189)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	362	Target Neighborhood Hits	284	Shared Neighborhood Hits	136
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID1_HUMAN
NC score	0.330597 (rank : 190)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	160
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID2_HUMAN
NC score	0.329867 (rank : 191)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	362	Target Neighborhood Hits	456	Shared Neighborhood Hits	167
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

FBLN3_HUMAN
NC score	0.329486 (rank : 192)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	362	Target Neighborhood Hits	293	Shared Neighborhood Hits	134
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

UROM_MOUSE
NC score	0.328653 (rank : 193)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	362	Target Neighborhood Hits	276	Shared Neighborhood Hits	136
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

NID1_MOUSE
NC score	0.327260 (rank : 194)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	362	Target Neighborhood Hits	335	Shared Neighborhood Hits	156
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

TSP3_MOUSE
NC score	0.325795 (rank : 195)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	362	Target Neighborhood Hits	247	Shared Neighborhood Hits	134
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

ESM1_HUMAN
NC score	0.324087 (rank : 196)	θ value	1.53129e-07 (rank : 58)
Query Neighborhood Hits	362	Target Neighborhood Hits	110	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LAMA3_HUMAN
NC score	0.324086 (rank : 197)	θ value	0.21417 (rank : 212)
Query Neighborhood Hits	362	Target Neighborhood Hits	760	Shared Neighborhood Hits	160
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

GAS6_MOUSE
NC score	0.323684 (rank : 198)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	362	Target Neighborhood Hits	343	Shared Neighborhood Hits	154
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

PROS_MOUSE
NC score	0.323368 (rank : 199)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	362	Target Neighborhood Hits	330	Shared Neighborhood Hits	153
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

TSP3_HUMAN
NC score	0.322461 (rank : 200)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	362	Target Neighborhood Hits	250	Shared Neighborhood Hits	129
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

NID2_MOUSE
NC score	0.321895 (rank : 201)	θ value	1.38821 (rank : 267)
Query Neighborhood Hits	362	Target Neighborhood Hits	338	Shared Neighborhood Hits	156
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

GAS6_HUMAN
NC score	0.320821 (rank : 202)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	362	Target Neighborhood Hits	348	Shared Neighborhood Hits	153
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

PROS_HUMAN
NC score	0.320562 (rank : 203)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	362	Target Neighborhood Hits	340	Shared Neighborhood Hits	157
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

LDLR_HUMAN
NC score	0.320519 (rank : 204)	θ value	0.00509761 (rank : 148)
Query Neighborhood Hits	362	Target Neighborhood Hits	375	Shared Neighborhood Hits	170
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

KR124_HUMAN
NC score	0.320280 (rank : 205)	θ value	0.0961366 (rank : 195)
Query Neighborhood Hits	362	Target Neighborhood Hits	124	Shared Neighborhood Hits	89
SwissProt Accessions	P60329	Gene names	KRTAP12-4, KAP12.4, KRTAP12.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-4 (Keratin-associated protein 12.4) (High sulfur keratin-associated protein 12.4).

LRP2_HUMAN
NC score	0.319493 (rank : 206)	θ value	0.813845 (rank : 246)
Query Neighborhood Hits	362	Target Neighborhood Hits	573	Shared Neighborhood Hits	221
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LAMA4_HUMAN
NC score	0.319478 (rank : 207)	θ value	0.125558 (rank : 203)
Query Neighborhood Hits	362	Target Neighborhood Hits	708	Shared Neighborhood Hits	147
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

EGFL7_HUMAN
NC score	0.319001 (rank : 208)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	362	Target Neighborhood Hits	325	Shared Neighborhood Hits	160
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGF_HUMAN
NC score	0.318749 (rank : 209)	θ value	0.00228821 (rank : 132)
Query Neighborhood Hits	362	Target Neighborhood Hits	343	Shared Neighborhood Hits	150
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

WISP2_MOUSE
NC score	0.317893 (rank : 210)	θ value	0.00869519 (rank : 159)
Query Neighborhood Hits	362	Target Neighborhood Hits	129	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0G4, Q8CIC8	Gene names	Wisp2, Ccn5, Ctgfl
Domain Architecture
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).

FBLN3_MOUSE
NC score	0.317725 (rank : 211)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	362	Target Neighborhood Hits	279	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

NET4_HUMAN
NC score	0.317223 (rank : 212)	θ value	0.0563607 (rank : 187)
Query Neighborhood Hits	362	Target Neighborhood Hits	191	Shared Neighborhood Hits	116
SwissProt Accessions	Q9HB63, Q658K9, Q7L3F1, Q7L9D6, Q7Z5B6, Q9BZP1, Q9NT44, Q9P133	Gene names	NTN4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin) (Hepar-derived netrin-like protein).

NOV_HUMAN
NC score	0.316347 (rank : 213)	θ value	0.00298849 (rank : 140)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	87
SwissProt Accessions	P48745, Q96BY5	Gene names	NOV, CCN3, IGFBP9, NOVH
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

NET4_MOUSE
NC score	0.316336 (rank : 214)	θ value	0.0961366 (rank : 197)
Query Neighborhood Hits	362	Target Neighborhood Hits	180	Shared Neighborhood Hits	117
SwissProt Accessions	Q9JI33	Gene names	Ntn4
Domain Architecture	No domain graphic available
Description	Netrin-4 precursor (Beta-netrin).

KR122_HUMAN
NC score	0.315994 (rank : 215)	θ value	0.00134147 (rank : 125)
Query Neighborhood Hits	362	Target Neighborhood Hits	97	Shared Neighborhood Hits	76
SwissProt Accessions	P59991	Gene names	KRTAP12-2, KAP12.2, KRTAP12.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-2 (Keratin-associated protein 12.2) (High sulfur keratin-associated protein 12.2).

EGFL7_MOUSE
NC score	0.314225 (rank : 216)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	362	Target Neighborhood Hits	287	Shared Neighborhood Hits	147
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

SLIT1_HUMAN
NC score	0.313156 (rank : 217)	θ value	0.00665767 (rank : 154)
Query Neighborhood Hits	362	Target Neighborhood Hits	700	Shared Neighborhood Hits	197
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

NET2_HUMAN
NC score	0.312455 (rank : 218)	θ value	0.0148317 (rank : 168)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	117
SwissProt Accessions	O00634	Gene names	NTN2L
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor.

NET2_MOUSE
NC score	0.310803 (rank : 219)	θ value	0.21417 (rank : 214)
Query Neighborhood Hits	362	Target Neighborhood Hits	193	Shared Neighborhood Hits	120
SwissProt Accessions	Q9R1A3, Q9QY49, Q9WVA6	Gene names	Ntn2l, Ntn3
Domain Architecture	No domain graphic available
Description	Netrin-2-like protein precursor (Netrin-3).

LDLR_MOUSE
NC score	0.310421 (rank : 220)	θ value	0.000786445 (rank : 119)
Query Neighborhood Hits	362	Target Neighborhood Hits	382	Shared Neighborhood Hits	168
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

SLIT1_MOUSE
NC score	0.309559 (rank : 221)	θ value	0.125558 (rank : 206)
Query Neighborhood Hits	362	Target Neighborhood Hits	715	Shared Neighborhood Hits	203
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

SLIT2_HUMAN
NC score	0.308414 (rank : 222)	θ value	0.00665767 (rank : 155)
Query Neighborhood Hits	362	Target Neighborhood Hits	708	Shared Neighborhood Hits	209
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

CTGF_HUMAN
NC score	0.307725 (rank : 223)	θ value	0.00869519 (rank : 156)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	86
SwissProt Accessions	P29279, Q96QX2	Gene names	CTGF, CCN2, HCS24
Domain Architecture
Description	Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).

HHIP_MOUSE
NC score	0.306916 (rank : 224)	θ value	8.99809 (rank : 355)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	130
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

CYR61_HUMAN
NC score	0.305432 (rank : 225)	θ value	0.00134147 (rank : 121)
Query Neighborhood Hits	362	Target Neighborhood Hits	159	Shared Neighborhood Hits	102
SwissProt Accessions	O00622, O14934, O43775, Q9BZL7	Gene names	CYR61, CCN1, GIG1, IGFBP10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).

SLIT3_MOUSE
NC score	0.304727 (rank : 226)	θ value	6.88961 (rank : 343)
Query Neighborhood Hits	362	Target Neighborhood Hits	700	Shared Neighborhood Hits	207
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

CYR61_MOUSE
NC score	0.304194 (rank : 227)	θ value	0.00134147 (rank : 122)
Query Neighborhood Hits	362	Target Neighborhood Hits	156	Shared Neighborhood Hits	99
SwissProt Accessions	P18406	Gene names	Cyr61, Ccn1, Igfbp10
Domain Architecture
Description	Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).

VLDLR_HUMAN
NC score	0.304121 (rank : 228)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	362	Target Neighborhood Hits	383	Shared Neighborhood Hits	171
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

SLIT2_MOUSE
NC score	0.301799 (rank : 229)	θ value	0.000158464 (rank : 109)
Query Neighborhood Hits	362	Target Neighborhood Hits	684	Shared Neighborhood Hits	197
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

ESM1_MOUSE
NC score	0.301662 (rank : 230)	θ value	0.000786445 (rank : 118)
Query Neighborhood Hits	362	Target Neighborhood Hits	107	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

EMR1_HUMAN
NC score	0.301457 (rank : 231)	θ value	0.47712 (rank : 229)
Query Neighborhood Hits	362	Target Neighborhood Hits	382	Shared Neighborhood Hits	144
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

LCE1C_HUMAN
NC score	0.301228 (rank : 232)	θ value	2.36792 (rank : 287)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	47
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LRP8_MOUSE
NC score	0.298157 (rank : 233)	θ value	0.00665767 (rank : 153)
Query Neighborhood Hits	362	Target Neighborhood Hits	385	Shared Neighborhood Hits	160
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

VLDLR_MOUSE
NC score	0.294551 (rank : 234)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	362	Target Neighborhood Hits	360	Shared Neighborhood Hits	158
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WISP2_HUMAN
NC score	0.294070 (rank : 235)	θ value	0.0330416 (rank : 181)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	O76076	Gene names	WISP2, CCN5, CT58, CTGFL
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).

WISP1_MOUSE
NC score	0.293833 (rank : 236)	θ value	0.00020696 (rank : 110)
Query Neighborhood Hits	362	Target Neighborhood Hits	123	Shared Neighborhood Hits	80
SwissProt Accessions	O54775, Q80ZL1	Gene names	Wisp1, Ccn4, Elm1
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (ELM-1).

ATRN_MOUSE
NC score	0.291938 (rank : 237)	θ value	2.36792 (rank : 280)
Query Neighborhood Hits	362	Target Neighborhood Hits	519	Shared Neighborhood Hits	181
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

PGBM_MOUSE
NC score	0.290403 (rank : 238)	θ value	0.000270298 (rank : 114)
Query Neighborhood Hits	362	Target Neighborhood Hits	1073	Shared Neighborhood Hits	218
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SLIT3_HUMAN
NC score	0.288487 (rank : 239)	θ value	0.0148317 (rank : 169)
Query Neighborhood Hits	362	Target Neighborhood Hits	682	Shared Neighborhood Hits	186
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

MATN3_MOUSE
NC score	0.288331 (rank : 240)	θ value	0.00869519 (rank : 158)
Query Neighborhood Hits	362	Target Neighborhood Hits	261	Shared Neighborhood Hits	116
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

KR123_HUMAN
NC score	0.287755 (rank : 241)	θ value	0.47712 (rank : 231)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	58
SwissProt Accessions	P60328	Gene names	KRTAP12-3, KAP12.3, KRTAP12.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-3 (Keratin-associated protein 12.3) (High sulfur keratin-associated protein 12.3).

ATRN_HUMAN
NC score	0.287734 (rank : 242)	θ value	6.88961 (rank : 333)
Query Neighborhood Hits	362	Target Neighborhood Hits	525	Shared Neighborhood Hits	180
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

SUSD1_HUMAN
NC score	0.285918 (rank : 243)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	362	Target Neighborhood Hits	285	Shared Neighborhood Hits	111
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NET1_HUMAN
NC score	0.285718 (rank : 244)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	362	Target Neighborhood Hits	149	Shared Neighborhood Hits	96
SwissProt Accessions	O95631	Gene names	NTN1, NTN1L
Domain Architecture
Description	Netrin-1 precursor.

CTGF_MOUSE
NC score	0.285449 (rank : 245)	θ value	0.0193708 (rank : 172)
Query Neighborhood Hits	362	Target Neighborhood Hits	124	Shared Neighborhood Hits	86
SwissProt Accessions	P29268, Q922U0	Gene names	Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain Architecture
Description	Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).

LCE1B_HUMAN
NC score	0.285175 (rank : 246)	θ value	6.88961 (rank : 338)
Query Neighborhood Hits	362	Target Neighborhood Hits	58	Shared Neighborhood Hits	45
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

EGFL8_HUMAN
NC score	0.284923 (rank : 247)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	362	Target Neighborhood Hits	270	Shared Neighborhood Hits	120
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

PGBM_HUMAN
NC score	0.283089 (rank : 248)	θ value	7.1131e-05 (rank : 100)
Query Neighborhood Hits	362	Target Neighborhood Hits	1113	Shared Neighborhood Hits	211
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MATN3_HUMAN
NC score	0.282541 (rank : 249)	θ value	0.00298849 (rank : 138)
Query Neighborhood Hits	362	Target Neighborhood Hits	268	Shared Neighborhood Hits	113
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

NOV_MOUSE
NC score	0.282439 (rank : 250)	θ value	0.000461057 (rank : 117)
Query Neighborhood Hits	362	Target Neighborhood Hits	130	Shared Neighborhood Hits	83
SwissProt Accessions	Q64299, Q8CA67	Gene names	Nov, Ccn3
Domain Architecture
Description	Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).

LCE1E_HUMAN
NC score	0.282191 (rank : 251)	θ value	2.36792 (rank : 288)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

ITB5_MOUSE
NC score	0.281123 (rank : 252)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	194
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB2_MOUSE
NC score	0.280798 (rank : 253)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	362	Target Neighborhood Hits	326	Shared Neighborhood Hits	193
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

TECTA_MOUSE
NC score	0.280469 (rank : 254)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	362	Target Neighborhood Hits	244	Shared Neighborhood Hits	136
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

ITB6_MOUSE
NC score	0.279129 (rank : 255)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	362	Target Neighborhood Hits	341	Shared Neighborhood Hits	192
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

WISP1_HUMAN
NC score	0.278444 (rank : 256)	θ value	7.1131e-05 (rank : 102)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	75
SwissProt Accessions	O95388, Q9HCS3	Gene names	WISP1, CCN4
Domain Architecture
Description	WNT1-inducible signaling pathway protein 1 precursor (WISP-1) (Wnt-1- induced secreted protein).

NET1_MOUSE
NC score	0.278423 (rank : 257)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	362	Target Neighborhood Hits	151	Shared Neighborhood Hits	94
SwissProt Accessions	O09118, Q60832, Q9QY50	Gene names	Ntn1
Domain Architecture
Description	Netrin-1 precursor.

ITB7_HUMAN
NC score	0.276827 (rank : 258)	θ value	0.21417 (rank : 211)
Query Neighborhood Hits	362	Target Neighborhood Hits	290	Shared Neighborhood Hits	182
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

EGFL8_MOUSE
NC score	0.275635 (rank : 259)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	362	Target Neighborhood Hits	266	Shared Neighborhood Hits	120
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

LCE1F_HUMAN
NC score	0.275214 (rank : 260)	θ value	1.81305 (rank : 272)
Query Neighborhood Hits	362	Target Neighborhood Hits	48	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

EMR2_HUMAN
NC score	0.273535 (rank : 261)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	362	Target Neighborhood Hits	345	Shared Neighborhood Hits	129
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

TECTA_HUMAN
NC score	0.273470 (rank : 262)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	362	Target Neighborhood Hits	239	Shared Neighborhood Hits	134
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

EMR1_MOUSE
NC score	0.272442 (rank : 263)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	362	Target Neighborhood Hits	349	Shared Neighborhood Hits	127
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

TENR_MOUSE
NC score	0.271976 (rank : 264)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	362	Target Neighborhood Hits	531	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

MATN4_HUMAN
NC score	0.271620 (rank : 265)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	362	Target Neighborhood Hits	287	Shared Neighborhood Hits	125
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

ITB6_HUMAN
NC score	0.271604 (rank : 266)	θ value	6.88961 (rank : 335)
Query Neighborhood Hits	362	Target Neighborhood Hits	318	Shared Neighborhood Hits	190
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

CD97_HUMAN
NC score	0.271531 (rank : 267)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	362	Target Neighborhood Hits	353	Shared Neighborhood Hits	133
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

LRP8_HUMAN
NC score	0.270266 (rank : 268)	θ value	4.03905 (rank : 312)
Query Neighborhood Hits	362	Target Neighborhood Hits	346	Shared Neighborhood Hits	143
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

ITB3_HUMAN
NC score	0.269632 (rank : 269)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	362	Target Neighborhood Hits	325	Shared Neighborhood Hits	191
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

EDIL3_MOUSE
NC score	0.268289 (rank : 270)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	362	Target Neighborhood Hits	317	Shared Neighborhood Hits	141
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TENR_HUMAN
NC score	0.268096 (rank : 271)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	362	Target Neighborhood Hits	526	Shared Neighborhood Hits	195
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB5_HUMAN
NC score	0.267842 (rank : 272)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	362	Target Neighborhood Hits	310	Shared Neighborhood Hits	184
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB1_HUMAN
NC score	0.266381 (rank : 273)	θ value	2.36792 (rank : 284)
Query Neighborhood Hits	362	Target Neighborhood Hits	298	Shared Neighborhood Hits	183
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

SORL_MOUSE
NC score	0.265520 (rank : 274)	θ value	0.0330416 (rank : 178)
Query Neighborhood Hits	362	Target Neighborhood Hits	439	Shared Neighborhood Hits	164
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

KR111_HUMAN
NC score	0.264298 (rank : 275)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	362	Target Neighborhood Hits	90	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUC1	Gene names	KRTAP11-1, KAP11.1, KRTAP11.1
Domain Architecture
Description	Keratin-associated protein 11-1 (High sulfur keratin-associated protein 11.1).

LCE1A_HUMAN
NC score	0.264058 (rank : 276)	θ value	1.06291 (rank : 251)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	32
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

WFDC3_HUMAN
NC score	0.263529 (rank : 277)	θ value	0.0330416 (rank : 180)
Query Neighborhood Hits	362	Target Neighborhood Hits	138	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IUB2, Q8TC52, Q9BQP3, Q9BQP4	Gene names	WFDC3, WAP14
Domain Architecture	No domain graphic available
Description	WAP four-disulfide core domain protein 3 precursor (Putative protease inhibitor WAP14).

ITB7_MOUSE
NC score	0.262150 (rank : 278)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	362	Target Neighborhood Hits	277	Shared Neighborhood Hits	178
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

MATN4_MOUSE
NC score	0.262001 (rank : 279)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	362	Target Neighborhood Hits	277	Shared Neighborhood Hits	124
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

PCSK5_HUMAN
NC score	0.261957 (rank : 280)	θ value	0.00228821 (rank : 135)
Query Neighborhood Hits	362	Target Neighborhood Hits	291	Shared Neighborhood Hits	151
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

ITB3_MOUSE
NC score	0.258410 (rank : 281)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	362	Target Neighborhood Hits	319	Shared Neighborhood Hits	182
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

EDIL3_HUMAN
NC score	0.257442 (rank : 282)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	362	Target Neighborhood Hits	292	Shared Neighborhood Hits	129
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

LCE1D_HUMAN
NC score	0.252285 (rank : 283)	θ value	4.03905 (rank : 311)
Query Neighborhood Hits	362	Target Neighborhood Hits	44	Shared Neighborhood Hits	31
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LRP4_HUMAN
NC score	0.250139 (rank : 284)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	362	Target Neighborhood Hits	355	Shared Neighborhood Hits	149
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

ITB1_MOUSE
NC score	0.249818 (rank : 285)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	362	Target Neighborhood Hits	283	Shared Neighborhood Hits	171
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
NC score	0.249802 (rank : 286)	θ value	2.36792 (rank : 285)
Query Neighborhood Hits	362	Target Neighborhood Hits	282	Shared Neighborhood Hits	167
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

CD248_HUMAN
NC score	0.249331 (rank : 287)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	362	Target Neighborhood Hits	679	Shared Neighborhood Hits	143
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LRP4_MOUSE
NC score	0.249185 (rank : 288)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	362	Target Neighborhood Hits	351	Shared Neighborhood Hits	147
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

KR261_HUMAN
NC score	0.248446 (rank : 289)	θ value	1.06291 (rank : 250)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PEX3	Gene names	KRTAP26-1, KAP26.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 26-1.

HMCN1_HUMAN
NC score	0.247972 (rank : 290)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	362	Target Neighborhood Hits	983	Shared Neighborhood Hits	184
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

SORL_HUMAN
NC score	0.247712 (rank : 291)	θ value	2.36792 (rank : 293)
Query Neighborhood Hits	362	Target Neighborhood Hits	440	Shared Neighborhood Hits	159
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

ITB4_HUMAN
NC score	0.246206 (rank : 292)	θ value	0.0252991 (rank : 176)
Query Neighborhood Hits	362	Target Neighborhood Hits	458	Shared Neighborhood Hits	159
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

CD248_MOUSE
NC score	0.241685 (rank : 293)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	362	Target Neighborhood Hits	578	Shared Neighborhood Hits	127
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

PCSK6_HUMAN
NC score	0.231771 (rank : 294)	θ value	0.0113563 (rank : 164)
Query Neighborhood Hits	362	Target Neighborhood Hits	298	Shared Neighborhood Hits	132
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

TENN_MOUSE
NC score	0.230730 (rank : 295)	θ value	0.47712 (rank : 235)
Query Neighborhood Hits	362	Target Neighborhood Hits	484	Shared Neighborhood Hits	190
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CFC1_HUMAN
NC score	0.229205 (rank : 296)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	362	Target Neighborhood Hits	148	Shared Neighborhood Hits	85
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CD97_MOUSE
NC score	0.226923 (rank : 297)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	362	Target Neighborhood Hits	295	Shared Neighborhood Hits	111
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

MCSP_MOUSE
NC score	0.222935 (rank : 298)	θ value	1.38821 (rank : 257)
Query Neighborhood Hits	362	Target Neighborhood Hits	108	Shared Neighborhood Hits	64
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

WISP3_HUMAN
NC score	0.220155 (rank : 299)	θ value	0.00134147 (rank : 127)
Query Neighborhood Hits	362	Target Neighborhood Hits	87	Shared Neighborhood Hits	56
SwissProt Accessions	O95389, Q6UXH6	Gene names	WISP3, CCN6
Domain Architecture	No domain graphic available
Description	WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

ELTD1_MOUSE
NC score	0.215199 (rank : 300)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	362	Target Neighborhood Hits	288	Shared Neighborhood Hits	106
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

CSPG2_MOUSE
NC score	0.208079 (rank : 301)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	362	Target Neighborhood Hits	711	Shared Neighborhood Hits	138
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

ITB8_HUMAN
NC score	0.207591 (rank : 302)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	362	Target Neighborhood Hits	280	Shared Neighborhood Hits	169
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

CSPG3_HUMAN
NC score	0.207406 (rank : 303)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	362	Target Neighborhood Hits	676	Shared Neighborhood Hits	137
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

HTRA1_HUMAN
NC score	0.207121 (rank : 304)	θ value	9.29e-05 (rank : 103)
Query Neighborhood Hits	362	Target Neighborhood Hits	155	Shared Neighborhood Hits	71
SwissProt Accessions	Q92743, Q9UNS5	Gene names	HTRA1, HTRA, PRSS11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).

TENN_HUMAN
NC score	0.206358 (rank : 305)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	362	Target Neighborhood Hits	453	Shared Neighborhood Hits	178
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MT4_MOUSE
NC score	0.205392 (rank : 306)	θ value	1.81305 (rank : 276)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	71
SwissProt Accessions	P47945	Gene names	Mt4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

CSPG3_MOUSE
NC score	0.205084 (rank : 307)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	362	Target Neighborhood Hits	657	Shared Neighborhood Hits	137
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

ZNFX1_HUMAN
NC score	0.204267 (rank : 308)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	362	Target Neighborhood Hits	308	Shared Neighborhood Hits	109
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CSPG2_HUMAN
NC score	0.203461 (rank : 309)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	362	Target Neighborhood Hits	681	Shared Neighborhood Hits	133
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TDGF1_MOUSE
NC score	0.200396 (rank : 310)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	362	Target Neighborhood Hits	146	Shared Neighborhood Hits	83
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

CELR2_HUMAN
NC score	0.200110 (rank : 311)	θ value	0.0736092 (rank : 191)
Query Neighborhood Hits	362	Target Neighborhood Hits	657	Shared Neighborhood Hits	185
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CFC1_MOUSE
NC score	0.199606 (rank : 312)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	362	Target Neighborhood Hits	125	Shared Neighborhood Hits	75
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

MT3_MOUSE
NC score	0.197874 (rank : 313)	θ value	1.38821 (rank : 265)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	42
SwissProt Accessions	P28184	Gene names	Mt3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF).

ZNFX1_MOUSE
NC score	0.196789 (rank : 314)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	362	Target Neighborhood Hits	407	Shared Neighborhood Hits	123
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

HTRA1_MOUSE
NC score	0.193842 (rank : 315)	θ value	8.40245e-06 (rank : 86)
Query Neighborhood Hits	362	Target Neighborhood Hits	140	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R118	Gene names	Htra1, Htra, Prss11
Domain Architecture
Description	Serine protease HTRA1 precursor (EC 3.4.21.-).

LYAM3_MOUSE
NC score	0.193425 (rank : 316)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	362	Target Neighborhood Hits	390	Shared Neighborhood Hits	131
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

PROZ_HUMAN
NC score	0.192634 (rank : 317)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	362	Target Neighborhood Hits	422	Shared Neighborhood Hits	121
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

HTRA3_HUMAN
NC score	0.190748 (rank : 318)	θ value	9.92553e-07 (rank : 71)
Query Neighborhood Hits	362	Target Neighborhood Hits	152	Shared Neighborhood Hits	63
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

PROZ_MOUSE
NC score	0.190296 (rank : 319)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	362	Target Neighborhood Hits	410	Shared Neighborhood Hits	117
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CELR3_MOUSE
NC score	0.189004 (rank : 320)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	362	Target Neighborhood Hits	687	Shared Neighborhood Hits	189
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

TEFF2_MOUSE
NC score	0.188236 (rank : 321)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	362	Target Neighborhood Hits	214	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

MT4_HUMAN
NC score	0.187602 (rank : 322)	θ value	1.38821 (rank : 266)
Query Neighborhood Hits	362	Target Neighborhood Hits	83	Shared Neighborhood Hits	60
SwissProt Accessions	P47944	Gene names	MT4
Domain Architecture	No domain graphic available
Description	Metallothionein-4 (MT-4) (Metallothionein-IV) (MT-IV).

HTRA3_MOUSE
NC score	0.186994 (rank : 323)	θ value	1.43324e-05 (rank : 88)
Query Neighborhood Hits	362	Target Neighborhood Hits	156	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

CELR3_HUMAN
NC score	0.186774 (rank : 324)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	362	Target Neighborhood Hits	680	Shared Neighborhood Hits	182
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

FATH_HUMAN
NC score	0.185140 (rank : 325)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	362	Target Neighborhood Hits	570	Shared Neighborhood Hits	158
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TEFF2_HUMAN
NC score	0.184774 (rank : 326)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	362	Target Neighborhood Hits	211	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

KR131_HUMAN
NC score	0.184709 (rank : 327)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	362	Target Neighborhood Hits	123	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IUC0, Q3LI79	Gene names	KRTAP13-1, KAP13.1, KRTAP13.1
Domain Architecture
Description	Keratin-associated protein 13-1 (High sulfur keratin-associated protein 13.1).

IBP7_MOUSE
NC score	0.183970 (rank : 328)	θ value	0.000121331 (rank : 104)
Query Neighborhood Hits	362	Target Neighborhood Hits	230	Shared Neighborhood Hits	50
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

CO1A1_MOUSE
NC score	0.182248 (rank : 329)	θ value	7.59969e-07 (rank : 68)
Query Neighborhood Hits	362	Target Neighborhood Hits	457	Shared Neighborhood Hits	59
SwissProt Accessions	P11087, Q53WT0, Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9	Gene names	Col1a1, Cola1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

MFGM_MOUSE
NC score	0.181438 (rank : 330)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	362	Target Neighborhood Hits	233	Shared Neighborhood Hits	103
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

CO1A1_HUMAN
NC score	0.180812 (rank : 331)	θ value	5.62301e-10 (rank : 36)
Query Neighborhood Hits	362	Target Neighborhood Hits	475	Shared Neighborhood Hits	56
SwissProt Accessions	P02452, P78441, Q13896, Q13902, Q13903, Q14037, Q14992, Q15176, Q15201, Q16050, Q7KZ30, Q7KZ34, Q8IVI5, Q9UML6, Q9UMM7	Gene names	COL1A1
Domain Architecture
Description	Collagen alpha-1(I) chain precursor.

KAZD1_HUMAN
NC score	0.178720 (rank : 332)	θ value	1.87187e-05 (rank : 91)
Query Neighborhood Hits	362	Target Neighborhood Hits	248	Shared Neighborhood Hits	55
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

FSTL3_MOUSE
NC score	0.177695 (rank : 333)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	362	Target Neighborhood Hits	152	Shared Neighborhood Hits	99
SwissProt Accessions	Q9EQC7	Gene names	Fstl3, Flrg
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

CELR1_HUMAN
NC score	0.177444 (rank : 334)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	362	Target Neighborhood Hits	613	Shared Neighborhood Hits	160
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

MT1X_HUMAN
NC score	0.176572 (rank : 335)	θ value	1.38821 (rank : 262)
Query Neighborhood Hits	362	Target Neighborhood Hits	76	Shared Neighborhood Hits	55
SwissProt Accessions	P80297	Gene names	MT1X
Domain Architecture	No domain graphic available
Description	Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX).

CELR1_MOUSE
NC score	0.176037 (rank : 336)	θ value	4.03905 (rank : 306)
Query Neighborhood Hits	362	Target Neighborhood Hits	617	Shared Neighborhood Hits	163
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CELR2_MOUSE
NC score	0.175877 (rank : 337)	θ value	0.0563607 (rank : 184)
Query Neighborhood Hits	362	Target Neighborhood Hits	584	Shared Neighborhood Hits	163
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LCE2D_HUMAN
NC score	0.173963 (rank : 338)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q5TA82	Gene names	LCE2D, LEP12, SPRL1A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).

MT2_MOUSE
NC score	0.172435 (rank : 339)	θ value	0.125558 (rank : 205)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	51
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

LCE2C_HUMAN
NC score	0.171030 (rank : 340)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5TA81	Gene names	LCE2C, LEP11
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2C (Late envelope protein 11).

LCE4A_HUMAN
NC score	0.170455 (rank : 341)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	362	Target Neighborhood Hits	26	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

KAZD1_MOUSE
NC score	0.170314 (rank : 342)	θ value	2.88788e-06 (rank : 82)
Query Neighborhood Hits	362	Target Neighborhood Hits	281	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

FSTL3_HUMAN
NC score	0.170167 (rank : 343)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	99
SwissProt Accessions	O95633	Gene names	FSTL3, FLRG
Domain Architecture
Description	Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).

LYAM3_HUMAN
NC score	0.170159 (rank : 344)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	362	Target Neighborhood Hits	378	Shared Neighborhood Hits	130
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_MOUSE
NC score	0.168879 (rank : 345)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	362	Target Neighborhood Hits	420	Shared Neighborhood Hits	141
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

IBP7_HUMAN
NC score	0.168484 (rank : 346)	θ value	0.000270298 (rank : 112)
Query Neighborhood Hits	362	Target Neighborhood Hits	220	Shared Neighborhood Hits	42
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

CO3A1_HUMAN
NC score	0.168212 (rank : 347)	θ value	7.59969e-07 (rank : 70)
Query Neighborhood Hits	362	Target Neighborhood Hits	452	Shared Neighborhood Hits	39
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LCE2A_HUMAN
NC score	0.167577 (rank : 348)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

TDGF2_HUMAN
NC score	0.166358 (rank : 349)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	362	Target Neighborhood Hits	131	Shared Neighborhood Hits	71
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TDGF1_HUMAN
NC score	0.166291 (rank : 350)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	362	Target Neighborhood Hits	132	Shared Neighborhood Hits	69
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

CO3A1_MOUSE
NC score	0.165260 (rank : 351)	θ value	2.21117e-06 (rank : 80)
Query Neighborhood Hits	362	Target Neighborhood Hits	466	Shared Neighborhood Hits	40
SwissProt Accessions	P08121, Q61429, Q9CRN7	Gene names	Col3a1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

LCE3A_HUMAN
NC score	0.164794 (rank : 352)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	362	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

MT3_HUMAN
NC score	0.164762 (rank : 353)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	362	Target Neighborhood Hits	82	Shared Neighborhood Hits	56
SwissProt Accessions	P25713, Q2V574	Gene names	MT3
Domain Architecture	No domain graphic available
Description	Metallothionein-3 (MT-3) (Metallothionein-III) (MT-III) (Growth inhibitory factor) (GIF) (GIFB).

FST_MOUSE
NC score	0.163613 (rank : 354)	θ value	1.81305 (rank : 270)
Query Neighborhood Hits	362	Target Neighborhood Hits	146	Shared Neighborhood Hits	79
SwissProt Accessions	P47931	Gene names	Fst
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

CO2A1_MOUSE
NC score	0.162651 (rank : 355)	θ value	7.59969e-07 (rank : 69)
Query Neighborhood Hits	362	Target Neighborhood Hits	483	Shared Neighborhood Hits	40
SwissProt Accessions	P28481	Gene names	Col2a1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

MT1_MOUSE
NC score	0.162370 (rank : 356)	θ value	1.38821 (rank : 263)
Query Neighborhood Hits	362	Target Neighborhood Hits	72	Shared Neighborhood Hits	49
SwissProt Accessions	P02802, Q64485	Gene names	Mt1
Domain Architecture	No domain graphic available
Description	Metallothionein-1 (MT-1) (Metallothionein-I) (MT-I).

KR121_HUMAN
NC score	0.161447 (rank : 357)	θ value	0.62314 (rank : 241)
Query Neighborhood Hits	362	Target Neighborhood Hits	37	Shared Neighborhood Hits	27
SwissProt Accessions	P59990	Gene names	KRTAP12-1, KAP12.1, KRTAP12.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 12-1 (Keratin-associated protein 12.1) (High sulfur keratin-associated protein 12.1).

KR134_HUMAN
NC score	0.160547 (rank : 358)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	362	Target Neighborhood Hits	81	Shared Neighborhood Hits	53
SwissProt Accessions	Q3LI77	Gene names	KRTAP13-4, KAP13.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-4.

LYAM2_HUMAN
NC score	0.160499 (rank : 359)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	362	Target Neighborhood Hits	394	Shared Neighborhood Hits	124
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LCE5A_HUMAN
NC score	0.160433 (rank : 360)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

ELTD1_HUMAN
NC score	0.159689 (rank : 361)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	362	Target Neighborhood Hits	269	Shared Neighborhood Hits	99
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

TNR16_HUMAN
NC score	0.156191 (rank : 362)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	362	Target Neighborhood Hits	183	Shared Neighborhood Hits	89
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

HTRA4_HUMAN
NC score	0.156080 (rank : 363)	θ value	0.62314 (rank : 239)
Query Neighborhood Hits	362	Target Neighborhood Hits	119	Shared Neighborhood Hits	54
SwissProt Accessions	P83105, Q542Z4, Q6PF13	Gene names	HTRA4
Domain Architecture	No domain graphic available
Description	Probable serine protease HTRA4 precursor (EC 3.4.21.-).

VEGFC_HUMAN
NC score	0.154525 (rank : 364)	θ value	0.365318 (rank : 227)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	81
SwissProt Accessions	P49767	Gene names	VEGFC
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

KR133_HUMAN
NC score	0.154455 (rank : 365)	θ value	3.0926 (rank : 301)
Query Neighborhood Hits	362	Target Neighborhood Hits	66	Shared Neighborhood Hits	59
SwissProt Accessions	Q3SY46, Q3LI78	Gene names	KRTAP13-3, KAP13.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-3.

IBP3_HUMAN
NC score	0.154130 (rank : 366)	θ value	0.00869519 (rank : 157)
Query Neighborhood Hits	362	Target Neighborhood Hits	67	Shared Neighborhood Hits	37
SwissProt Accessions	P17936, Q2V509, Q6P1M6	Gene names	IGFBP3, IBP3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

MT1H_HUMAN
NC score	0.154057 (rank : 367)	θ value	0.279714 (rank : 218)
Query Neighborhood Hits	362	Target Neighborhood Hits	78	Shared Neighborhood Hits	50
SwissProt Accessions	P80294	Gene names	MT1H
Domain Architecture	No domain graphic available
Description	Metallothionein-1H (MT-1H) (Metallothionein-IH) (MT-IH) (Metallothionein-0) (MT-0).

KR132_HUMAN
NC score	0.153912 (rank : 368)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	362	Target Neighborhood Hits	69	Shared Neighborhood Hits	55
SwissProt Accessions	Q52LG2	Gene names	KRTAP13-2, KAP13.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 13-2.

IBP5_MOUSE
NC score	0.153567 (rank : 369)	θ value	0.00134147 (rank : 124)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

MT1A_HUMAN
NC score	0.153218 (rank : 370)	θ value	4.03905 (rank : 313)
Query Neighborhood Hits	362	Target Neighborhood Hits	74	Shared Neighborhood Hits	48
SwissProt Accessions	P04731	Gene names	MT1A
Domain Architecture	No domain graphic available
Description	Metallothionein-1A (MT-1A) (Metallothionein-IA) (MT-IA).

ECM2_HUMAN
NC score	0.153015 (rank : 371)	θ value	1.69304e-06 (rank : 77)
Query Neighborhood Hits	362	Target Neighborhood Hits	402	Shared Neighborhood Hits	56
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

IBP5_HUMAN
NC score	0.152962 (rank : 372)	θ value	0.00134147 (rank : 123)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	36
SwissProt Accessions	P24593	Gene names	IGFBP5, IBP5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

CO5A2_HUMAN
NC score	0.150045 (rank : 373)	θ value	4.45536e-07 (rank : 66)
Query Neighborhood Hits	362	Target Neighborhood Hits	760	Shared Neighborhood Hits	67
SwissProt Accessions	P05997	Gene names	COL5A2
Domain Architecture
Description	Collagen alpha-2(V) chain precursor.

IBP3_MOUSE
NC score	0.149503 (rank : 374)	θ value	0.000270298 (rank : 111)
Query Neighborhood Hits	362	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	P47878	Gene names	Igfbp3, Igfbp-3
Domain Architecture
Description	Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).

LCE2B_HUMAN
NC score	0.148020 (rank : 375)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	27
SwissProt Accessions	O14633	Gene names	LCE2B, LEP10, SPRL1B, XP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).

TNR16_MOUSE
NC score	0.147830 (rank : 376)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	362	Target Neighborhood Hits	178	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

ADAM8_MOUSE
NC score	0.147014 (rank : 377)	θ value	3.0926 (rank : 299)
Query Neighborhood Hits	362	Target Neighborhood Hits	326	Shared Neighborhood Hits	154
SwissProt Accessions	Q05910	Gene names	Adam8, Ms2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD156 antigen).

TNR25_HUMAN
NC score	0.145369 (rank : 378)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	362	Target Neighborhood Hits	172	Shared Neighborhood Hits	69
SwissProt Accessions	Q93038, O00275, O00276, O00277, O00278, O00279, O00280, O14865, O14866, P78507, P78515, Q92983, Q93036, Q93037, Q99722, Q99830, Q99831, Q9BY86, Q9UME0, Q9UME1, Q9UME5	Gene names	TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 25 precursor (WSL-1 protein) (Apoptosis-mediating receptor DR3) (Apoptosis-mediating receptor TRAMP) (Death domain receptor 3) (WSL protein) (Apoptosis- inducing receptor AIR) (Apo-3) (Lymphocyte-associated receptor of death) (LARD).

ADAM8_HUMAN
NC score	0.144680 (rank : 379)	θ value	0.21417 (rank : 210)
Query Neighborhood Hits	362	Target Neighborhood Hits	327	Shared Neighborhood Hits	162
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

MUC13_MOUSE
NC score	0.144433 (rank : 380)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	362	Target Neighborhood Hits	447	Shared Neighborhood Hits	99
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

IBP2_MOUSE
NC score	0.143415 (rank : 381)	θ value	0.0431538 (rank : 183)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	37
SwissProt Accessions	P47877, Q61722	Gene names	Igfbp2, Igfbp-2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

CT127_HUMAN
NC score	0.143377 (rank : 382)	θ value	1.38821 (rank : 253)
Query Neighborhood Hits	362	Target Neighborhood Hits	67	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BQN2	Gene names	C20orf127
Domain Architecture	No domain graphic available
Description	Putative metallothionein C20orf127.

KR241_HUMAN
NC score	0.143255 (rank : 383)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	362	Target Neighborhood Hits	71	Shared Neighborhood Hits	53
SwissProt Accessions	Q3LI83	Gene names	KRTAP24-1, KAP24.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 24-1.

CRAC1_MOUSE
NC score	0.142724 (rank : 384)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	53
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

MT1L_HUMAN
NC score	0.142380 (rank : 385)	θ value	1.38821 (rank : 261)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	47
SwissProt Accessions	Q93083	Gene names	MT1L
Domain Architecture	No domain graphic available
Description	Metallothionein-1L (MT-1L) (Metallothionein-IL) (MT-IL).

FST_HUMAN
NC score	0.142199 (rank : 386)	θ value	1.81305 (rank : 269)
Query Neighborhood Hits	362	Target Neighborhood Hits	129	Shared Neighborhood Hits	65
SwissProt Accessions	P19883, Q9BTH0	Gene names	FST
Domain Architecture
Description	Follistatin precursor (FS) (Activin-binding protein).

HABP2_HUMAN
NC score	0.142004 (rank : 387)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	362	Target Neighborhood Hits	431	Shared Neighborhood Hits	136
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

IBP1_MOUSE
NC score	0.141521 (rank : 388)	θ value	0.125558 (rank : 202)
Query Neighborhood Hits	362	Target Neighborhood Hits	97	Shared Neighborhood Hits	44
SwissProt Accessions	P47876, Q61732	Gene names	Igfbp1, Igfbp-1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).

IBP2_HUMAN
NC score	0.140383 (rank : 389)	θ value	0.163984 (rank : 207)
Query Neighborhood Hits	362	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	P18065, Q14619, Q9UCL3	Gene names	IGFBP2, BP2
Domain Architecture
Description	Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).

HABP2_MOUSE
NC score	0.140001 (rank : 390)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	362	Target Neighborhood Hits	445	Shared Neighborhood Hits	134
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

CRAC1_HUMAN
NC score	0.139358 (rank : 391)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	362	Target Neighborhood Hits	111	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

IBP4_HUMAN
NC score	0.139197 (rank : 392)	θ value	0.00175202 (rank : 128)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	25
SwissProt Accessions	P22692	Gene names	IGFBP4, IBP4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

RSPO3_HUMAN
NC score	0.138166 (rank : 393)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	362	Target Neighborhood Hits	128	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

MT1B_HUMAN
NC score	0.137962 (rank : 394)	θ value	2.36792 (rank : 290)
Query Neighborhood Hits	362	Target Neighborhood Hits	87	Shared Neighborhood Hits	55
SwissProt Accessions	P07438	Gene names	MT1B
Domain Architecture	No domain graphic available
Description	Metallothionein-1B (MT-1B) (Metallothionein-IB) (MT-IB).

IBP4_MOUSE
NC score	0.137346 (rank : 395)	θ value	0.00298849 (rank : 137)
Query Neighborhood Hits	362	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	P47879, O35666	Gene names	Igfbp4, Igfbp-4
Domain Architecture
Description	Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).

TNR9_MOUSE
NC score	0.135627 (rank : 396)	θ value	0.0961366 (rank : 199)
Query Neighborhood Hits	362	Target Neighborhood Hits	137	Shared Neighborhood Hits	75
SwissProt Accessions	P20334	Gene names	Tnfrsf9, Cd137, Cd157, Ila, Ly63
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB) (CD137 antigen).

MT1G_HUMAN
NC score	0.135530 (rank : 397)	θ value	1.38821 (rank : 259)
Query Neighborhood Hits	362	Target Neighborhood Hits	63	Shared Neighborhood Hits	43
SwissProt Accessions	P13640, P80296	Gene names	MT1G, MT1K, MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1G (MT-1G) (Metallothionein-IG) (MT-IG) (Metallothionein-1K) (MT-1K).

NRX2A_HUMAN
NC score	0.135482 (rank : 398)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	362	Target Neighborhood Hits	614	Shared Neighborhood Hits	83
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

LYAM1_MOUSE
NC score	0.134609 (rank : 399)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	362	Target Neighborhood Hits	332	Shared Neighborhood Hits	112
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

UROL1_MOUSE
NC score	0.133261 (rank : 400)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	78
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

NRX1A_HUMAN
NC score	0.132346 (rank : 401)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	362	Target Neighborhood Hits	170	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

NRX1A_MOUSE
NC score	0.130882 (rank : 402)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	362	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

VEGFC_MOUSE
NC score	0.129424 (rank : 403)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	362	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

LYAM1_HUMAN
NC score	0.129087 (rank : 404)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	362	Target Neighborhood Hits	315	Shared Neighborhood Hits	102
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ADA15_HUMAN
NC score	0.128261 (rank : 405)	θ value	8.99809 (rank : 349)
Query Neighborhood Hits	362	Target Neighborhood Hits	288	Shared Neighborhood Hits	152
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

NRX3A_HUMAN
NC score	0.127780 (rank : 406)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	362	Target Neighborhood Hits	164	Shared Neighborhood Hits	67
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

ADA15_MOUSE
NC score	0.127042 (rank : 407)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	362	Target Neighborhood Hits	324	Shared Neighborhood Hits	155
SwissProt Accessions	O88839, Q3U7C2, Q8C7Z0, Q91VS9, Q9QYL2	Gene names	Adam15, Mdc15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin) (AD56).

RSPO3_MOUSE
NC score	0.125272 (rank : 408)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	362	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

TNR4_MOUSE
NC score	0.124785 (rank : 409)	θ value	5.27518 (rank : 325)
Query Neighborhood Hits	362	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	P47741	Gene names	Tnfrsf4, Ox40, Txgp1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (OX40 antigen).

ADA18_MOUSE
NC score	0.124752 (rank : 410)	θ value	0.0736092 (rank : 189)
Query Neighborhood Hits	362	Target Neighborhood Hits	227	Shared Neighborhood Hits	131
SwissProt Accessions	Q9R157, Q60621	Gene names	Adam18, Adam27, Dtgn3, Tmdc3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III) (ADAM 27).

ADA11_MOUSE
NC score	0.124581 (rank : 411)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	362	Target Neighborhood Hits	263	Shared Neighborhood Hits	142
SwissProt Accessions	Q9R1V4	Gene names	Adam11, Mdc
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

RSPO4_HUMAN
NC score	0.124457 (rank : 412)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	362	Target Neighborhood Hits	110	Shared Neighborhood Hits	56
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

MT1E_HUMAN
NC score	0.124213 (rank : 413)	θ value	1.81305 (rank : 275)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	50
SwissProt Accessions	P04732, Q86YX4	Gene names	MT1E
Domain Architecture	No domain graphic available
Description	Metallothionein-1E (MT-1E) (Metallothionein-IE) (MT-IE).

TNR14_HUMAN
NC score	0.123578 (rank : 414)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	362	Target Neighborhood Hits	149	Shared Neighborhood Hits	74
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ADA11_HUMAN
NC score	0.123536 (rank : 415)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	362	Target Neighborhood Hits	259	Shared Neighborhood Hits	142
SwissProt Accessions	O75078, Q14808, Q14809, Q14810	Gene names	ADAM11, MDC
Domain Architecture
Description	ADAM 11 precursor (A disintegrin and metalloproteinase domain 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC).

ADA17_HUMAN
NC score	0.122666 (rank : 416)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	362	Target Neighborhood Hits	223	Shared Neighborhood Hits	111
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

PERT_HUMAN
NC score	0.122440 (rank : 417)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	362	Target Neighborhood Hits	221	Shared Neighborhood Hits	77
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MT2_HUMAN
NC score	0.121723 (rank : 418)	θ value	1.38821 (rank : 264)
Query Neighborhood Hits	362	Target Neighborhood Hits	69	Shared Neighborhood Hits	47
SwissProt Accessions	P02795, Q14823, Q2HXR9, Q53XT9	Gene names	MT2A, CES1, MT2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II) (Metallothionein-2A).

IBP1_HUMAN
NC score	0.121165 (rank : 419)	θ value	4.03905 (rank : 309)
Query Neighborhood Hits	362	Target Neighborhood Hits	67	Shared Neighborhood Hits	40
SwissProt Accessions	P08833, Q8IYP5	Gene names	IGFBP1, IBP1
Domain Architecture
Description	Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).

TNR4_HUMAN
NC score	0.120193 (rank : 420)	θ value	3.0926 (rank : 304)
Query Neighborhood Hits	362	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	P43489, Q13663, Q5T7M0	Gene names	TNFRSF4, TXGP1L
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 4 precursor (OX40L receptor) (ACT35 antigen) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD134 antigen).

MT1F_HUMAN
NC score	0.119859 (rank : 421)	θ value	1.38821 (rank : 258)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	44
SwissProt Accessions	P04733, Q9UI97	Gene names	MT1F
Domain Architecture	No domain graphic available
Description	Metallothionein-1F (MT-1F) (Metallothionein-IF) (MT-IF).

TNR9_HUMAN
NC score	0.119828 (rank : 422)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	362	Target Neighborhood Hits	166	Shared Neighborhood Hits	86
SwissProt Accessions	Q07011	Gene names	TNFRSF9, CD137, ILA
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 9 precursor (4-1BB ligand receptor) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD137 antigen).

ADA19_MOUSE
NC score	0.118281 (rank : 423)	θ value	1.81305 (rank : 268)
Query Neighborhood Hits	362	Target Neighborhood Hits	315	Shared Neighborhood Hits	133
SwissProt Accessions	O35674	Gene names	Adam19, Mltnb
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta).

ADAM9_MOUSE
NC score	0.117992 (rank : 424)	θ value	6.88961 (rank : 332)
Query Neighborhood Hits	362	Target Neighborhood Hits	325	Shared Neighborhood Hits	149
SwissProt Accessions	Q61072, Q60618, Q61853, Q80U94	Gene names	Adam9, Kiaa0021, Mdc9, Mltng
Domain Architecture	No domain graphic available
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma).

CO6_HUMAN
NC score	0.117939 (rank : 425)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	362	Target Neighborhood Hits	331	Shared Neighborhood Hits	100
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

CNTP2_HUMAN
NC score	0.117557 (rank : 426)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	362	Target Neighborhood Hits	199	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
NC score	0.117553 (rank : 427)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	83
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

MKS3_MOUSE
NC score	0.117180 (rank : 428)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	362	Target Neighborhood Hits	89	Shared Neighborhood Hits	60
SwissProt Accessions	Q8BR76, Q78U07	Gene names	Tmem67, Mks3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67).

PERT_MOUSE
NC score	0.117000 (rank : 429)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	362	Target Neighborhood Hits	221	Shared Neighborhood Hits	76
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

RSPO2_HUMAN
NC score	0.116358 (rank : 430)	θ value	0.813845 (rank : 247)
Query Neighborhood Hits	362	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

ADA23_HUMAN
NC score	0.116298 (rank : 431)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	118
SwissProt Accessions	O75077	Gene names	ADAM23, MDC3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

TNR8_MOUSE
NC score	0.115866 (rank : 432)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	362	Target Neighborhood Hits	208	Shared Neighborhood Hits	70
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

SPR2D_MOUSE
NC score	0.115681 (rank : 433)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	362	Target Neighborhood Hits	61	Shared Neighborhood Hits	23
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

UROL1_HUMAN
NC score	0.115672 (rank : 434)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	362	Target Neighborhood Hits	213	Shared Neighborhood Hits	73
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

TIE1_HUMAN
NC score	0.115323 (rank : 435)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	362	Target Neighborhood Hits	1241	Shared Neighborhood Hits	173
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

MATN1_MOUSE
NC score	0.115307 (rank : 436)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	362	Target Neighborhood Hits	186	Shared Neighborhood Hits	62
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MT1M_HUMAN
NC score	0.114732 (rank : 437)	θ value	0.21417 (rank : 213)
Query Neighborhood Hits	362	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N339, Q8TDN3	Gene names	MT1M
Domain Architecture	No domain graphic available
Description	Metallothionein-1M (MT-1M) (Metallothionein-IM) (MT-IM).

RELN_MOUSE
NC score	0.114545 (rank : 438)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	105
SwissProt Accessions	Q60841, Q9CUA6	Gene names	Reln, Rl
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-) (Reeler protein).

RSPO2_MOUSE
NC score	0.113864 (rank : 439)	θ value	2.36792 (rank : 292)
Query Neighborhood Hits	362	Target Neighborhood Hits	88	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

CORIN_HUMAN
NC score	0.113786 (rank : 440)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	362	Target Neighborhood Hits	453	Shared Neighborhood Hits	144
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

ADA33_HUMAN
NC score	0.113758 (rank : 441)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	362	Target Neighborhood Hits	264	Shared Neighborhood Hits	128
SwissProt Accessions	Q9BZ11, Q5JT75, Q5JT76, Q8N0W6	Gene names	ADAM33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

LRP6_HUMAN
NC score	0.113565 (rank : 442)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	362	Target Neighborhood Hits	235	Shared Neighborhood Hits	85
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

RSPO4_MOUSE
NC score	0.113416 (rank : 443)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	362	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ADA19_HUMAN
NC score	0.113371 (rank : 444)	θ value	3.0926 (rank : 296)
Query Neighborhood Hits	362	Target Neighborhood Hits	381	Shared Neighborhood Hits	124
SwissProt Accessions	Q9H013, Q9BZL5, Q9UHP2	Gene names	ADAM19, MLTNB
Domain Architecture
Description	ADAM 19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 19) (Meltrin beta) (Metalloprotease and disintegrin dentritic antigen marker) (MADDAM).

MATN1_HUMAN
NC score	0.113366 (rank : 445)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	362	Target Neighborhood Hits	191	Shared Neighborhood Hits	66
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

TNR7_HUMAN
NC score	0.112559 (rank : 446)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	362	Target Neighborhood Hits	120	Shared Neighborhood Hits	70
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

TNR8_HUMAN
NC score	0.112438 (rank : 447)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	362	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	P28908	Gene names	TNFRSF8, CD30
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30) (KI-1 antigen).

LRP6_MOUSE
NC score	0.112310 (rank : 448)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	362	Target Neighborhood Hits	232	Shared Neighborhood Hits	83
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP5_MOUSE
NC score	0.111858 (rank : 449)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

TIE1_MOUSE
NC score	0.111789 (rank : 450)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	362	Target Neighborhood Hits	1266	Shared Neighborhood Hits	176
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

PGCA_HUMAN
NC score	0.111682 (rank : 451)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	362	Target Neighborhood Hits	821	Shared Neighborhood Hits	105
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

ADA23_MOUSE
NC score	0.111625 (rank : 452)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	362	Target Neighborhood Hits	245	Shared Neighborhood Hits	127
SwissProt Accessions	Q9R1V7, Q6QDY9, Q6QDZ0, Q8CC33	Gene names	Adam23, Mdc3
Domain Architecture	No domain graphic available
Description	ADAM 23 precursor (A disintegrin and metalloproteinase domain 23) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) (MDC-3).

ADAM7_HUMAN
NC score	0.110177 (rank : 453)	θ value	0.365318 (rank : 219)
Query Neighborhood Hits	362	Target Neighborhood Hits	221	Shared Neighborhood Hits	132
SwissProt Accessions	Q9H2U9, O75959	Gene names	ADAM7, GP83
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7) (Sperm maturation-related glycoprotein GP-83).

CNTP4_MOUSE
NC score	0.110147 (rank : 454)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	362	Target Neighborhood Hits	193	Shared Neighborhood Hits	80
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

RELN_HUMAN
NC score	0.110141 (rank : 455)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	362	Target Neighborhood Hits	233	Shared Neighborhood Hits	102
SwissProt Accessions	P78509, Q86UJ0, Q86UJ8, Q8NDV0, Q9UDQ2	Gene names	RELN
Domain Architecture
Description	Reelin precursor (EC 3.4.21.-).

FAT2_HUMAN
NC score	0.109810 (rank : 456)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	362	Target Neighborhood Hits	507	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

LCE3B_HUMAN
NC score	0.109167 (rank : 457)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

CO7_HUMAN
NC score	0.108404 (rank : 458)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	362	Target Neighborhood Hits	278	Shared Neighborhood Hits	86
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

ADA33_MOUSE
NC score	0.107770 (rank : 459)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	362	Target Neighborhood Hits	231	Shared Neighborhood Hits	117
SwissProt Accessions	Q923W9	Gene names	Adam33
Domain Architecture
Description	ADAM 33 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 33).

ADAM9_HUMAN
NC score	0.107767 (rank : 460)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	362	Target Neighborhood Hits	243	Shared Neighborhood Hits	136
SwissProt Accessions	Q13443, Q10718, Q8NFM6	Gene names	ADAM9, KIAA0021, MCMP, MDC9, MLTNG
Domain Architecture
Description	ADAM 9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 9) (Metalloprotease/disintegrin/cysteine-rich protein 9) (Myeloma cell metalloproteinase) (Meltrin gamma) (Cellular disintegrin-related protein).

MT1I_HUMAN
NC score	0.107691 (rank : 461)	θ value	1.38821 (rank : 260)
Query Neighborhood Hits	362	Target Neighborhood Hits	64	Shared Neighborhood Hits	41
SwissProt Accessions	P80295	Gene names	MT1I
Domain Architecture	No domain graphic available
Description	Metallothionein-1I (MT-1I) (Metallothionein-II).

ADA28_MOUSE
NC score	0.106544 (rank : 462)	θ value	0.0961366 (rank : 194)
Query Neighborhood Hits	362	Target Neighborhood Hits	241	Shared Neighborhood Hits	130
SwissProt Accessions	Q9JLN6, Q8K5D2, Q8K5D3	Gene names	Adam28
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Thymic epithelial cell-ADAM) (TECADAM).

CNTP4_HUMAN
NC score	0.106489 (rank : 463)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	362	Target Neighborhood Hits	187	Shared Neighborhood Hits	73
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

SPR2B_MOUSE
NC score	0.106461 (rank : 464)	θ value	4.03905 (rank : 314)
Query Neighborhood Hits	362	Target Neighborhood Hits	51	Shared Neighborhood Hits	26
SwissProt Accessions	O70554, Q7TSB2	Gene names	Sprr2b
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2B.

EMR3_HUMAN
NC score	0.106192 (rank : 465)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	362	Target Neighborhood Hits	245	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

ADM1A_MOUSE
NC score	0.106156 (rank : 466)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	362	Target Neighborhood Hits	230	Shared Neighborhood Hits	139
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA18_HUMAN
NC score	0.105528 (rank : 467)	θ value	0.813845 (rank : 242)
Query Neighborhood Hits	362	Target Neighborhood Hits	184	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y3Q7, Q6UXJ9	Gene names	ADAM18, TMDC3
Domain Architecture
Description	ADAM 18 precursor (A disintegrin and metalloproteinase domain 18) (Transmembrane metalloproteinase-like, disintegrin-like, and cysteine- rich protein III) (tMDC III).

WFDC2_HUMAN
NC score	0.105478 (rank : 468)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	48
SwissProt Accessions	Q14508, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1	Gene names	WFDC2, HE4, WAP5
Domain Architecture
Description	WAP four-disulfide core domain protein 2 precursor (Major epididymis- specific protein E4) (Epididymal secretory protein E4) (Putative protease inhibitor WAP5).

HGFA_HUMAN
NC score	0.105204 (rank : 469)	θ value	8.99809 (rank : 354)
Query Neighborhood Hits	362	Target Neighborhood Hits	436	Shared Neighborhood Hits	115
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LRP5_HUMAN
NC score	0.105161 (rank : 470)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	362	Target Neighborhood Hits	224	Shared Neighborhood Hits	83
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

TNR23_MOUSE
NC score	0.104533 (rank : 471)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	362	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	Q9ER63, Q8VHC0	Gene names	Tnfrsf23, Dctrailr1, Tnfrh1, Tnfrsf1al1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 23 precursor (Tumor necrosis factor receptor p60 homolog 1) (TNF receptor family member SOB) (Decoy TRAIL receptor 1) (TNF receptor homolog 1).

MKS3_HUMAN
NC score	0.104481 (rank : 472)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	362	Target Neighborhood Hits	79	Shared Neighborhood Hits	53
SwissProt Accessions	Q5HYA8, Q3ZCX3, Q7Z5T8, Q8IZ06	Gene names	TMEM67, MKS3
Domain Architecture	No domain graphic available
Description	Meckelin (Meckel syndrome type 3 protein) (Transmembrane protein 67).

PROP_MOUSE
NC score	0.104419 (rank : 473)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	362	Target Neighborhood Hits	165	Shared Neighborhood Hits	42
SwissProt Accessions	P11680, Q3TB98, Q3U779	Gene names	Cfp, Pfc
Domain Architecture	No domain graphic available
Description	Properdin precursor (Factor P).

ADA10_MOUSE
NC score	0.103965 (rank : 474)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

PGCB_MOUSE
NC score	0.103441 (rank : 475)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	362	Target Neighborhood Hits	459	Shared Neighborhood Hits	95
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

SPR2G_MOUSE
NC score	0.103001 (rank : 476)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	22
SwissProt Accessions	O70558	Gene names	Sprr2g
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2G.

ADA10_HUMAN
NC score	0.102402 (rank : 477)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	362	Target Neighborhood Hits	189	Shared Neighborhood Hits	98
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

ADA17_MOUSE
NC score	0.102294 (rank : 478)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	362	Target Neighborhood Hits	201	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Z0F8, O88726, Q9R1U4, Q9Z0K3	Gene names	Adam17, Tace
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (CD156b antigen).

ADAM2_MOUSE
NC score	0.102183 (rank : 479)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	362	Target Neighborhood Hits	209	Shared Neighborhood Hits	110
SwissProt Accessions	Q60718, Q60814, Q9D4G3, Q9QWJ0	Gene names	Adam2, Ftnb
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30) (PH30-beta).

HGFA_MOUSE
NC score	0.101534 (rank : 480)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	115
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ADA28_HUMAN
NC score	0.100805 (rank : 481)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	362	Target Neighborhood Hits	244	Shared Neighborhood Hits	139
SwissProt Accessions	Q9UKQ2, Q9Y339, Q9Y3S0	Gene names	ADAM28, MDCL
Domain Architecture
Description	ADAM 28 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 28) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein-L) (MDC-L) (eMDC II) (ADAM23).

CO8B_MOUSE
NC score	0.100579 (rank : 482)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	362	Target Neighborhood Hits	224	Shared Neighborhood Hits	73
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

TIE2_MOUSE
NC score	0.099981 (rank : 483)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	362	Target Neighborhood Hits	1204	Shared Neighborhood Hits	154
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

ADA22_MOUSE
NC score	0.099870 (rank : 484)	θ value	6.88961 (rank : 331)
Query Neighborhood Hits	362	Target Neighborhood Hits	225	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R1V6, Q5TLI8, Q5TLI9, Q5TLJ0, Q5TLJ1, Q5TLJ2, Q5TLJ3, Q5TLJ4, Q5TLJ5, Q5TLJ6, Q5TLJ7, Q5TLJ8, Q5TLJ9, Q5TLK0, Q5TLK1, Q5TLK2, Q5TLK3, Q5TLK4, Q5TLK5, Q5TLK6, Q5TLK7, Q5TLK8, Q8BSF2, Q9R1V5	Gene names	Adam22
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22).

FA10_MOUSE
NC score	0.099634 (rank : 485)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	362	Target Neighborhood Hits	435	Shared Neighborhood Hits	116
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

PROC_MOUSE
NC score	0.099355 (rank : 486)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	362	Target Neighborhood Hits	426	Shared Neighborhood Hits	122
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

CSPG4_HUMAN
NC score	0.098561 (rank : 487)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

ADA12_HUMAN
NC score	0.098117 (rank : 488)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	362	Target Neighborhood Hits	224	Shared Neighborhood Hits	104
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

FREM2_MOUSE
NC score	0.097910 (rank : 489)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

TNR5_MOUSE
NC score	0.097704 (rank : 490)	θ value	1.81305 (rank : 277)
Query Neighborhood Hits	362	Target Neighborhood Hits	131	Shared Neighborhood Hits	61
SwissProt Accessions	P27512, Q99NE0, Q99NE1, Q99NE2, Q99NE3	Gene names	Cd40, Tnfrsf5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (BP50) (CDw40).

ADA32_HUMAN
NC score	0.097473 (rank : 491)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	362	Target Neighborhood Hits	216	Shared Neighborhood Hits	116
SwissProt Accessions	Q8TC27, Q8TC42	Gene names	ADAM32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

TIE2_HUMAN
NC score	0.097124 (rank : 492)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	362	Target Neighborhood Hits	1192	Shared Neighborhood Hits	151
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

CNTP3_HUMAN
NC score	0.096930 (rank : 493)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	362	Target Neighborhood Hits	195	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

FA10_HUMAN
NC score	0.096719 (rank : 494)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	362	Target Neighborhood Hits	431	Shared Neighborhood Hits	112
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CORIN_MOUSE
NC score	0.096664 (rank : 495)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	362	Target Neighborhood Hits	451	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CLC14_MOUSE
NC score	0.096555 (rank : 496)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	362	Target Neighborhood Hits	120	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

FA9_HUMAN
NC score	0.096450 (rank : 497)	θ value	5.27518 (rank : 319)
Query Neighborhood Hits	362	Target Neighborhood Hits	421	Shared Neighborhood Hits	106
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FREM2_HUMAN
NC score	0.096263 (rank : 498)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	362	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FA12_HUMAN
NC score	0.095625 (rank : 499)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	362	Target Neighborhood Hits	425	Shared Neighborhood Hits	108
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

ADA24_MOUSE
NC score	0.094885 (rank : 500)	θ value	2.36792 (rank : 279)
Query Neighborhood Hits	362	Target Neighborhood Hits	230	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R160	Gene names	Adam24
Domain Architecture
Description	ADAM 24 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 24) (Testase 1).

CSPG4_MOUSE
NC score	0.094708 (rank : 501)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	362	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

RSPO1_HUMAN
NC score	0.094592 (rank : 502)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	362	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	Q2MKA7, Q5T0F2, Q8N7L5	Gene names	RSPO1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (hRspo1).

ADA22_HUMAN
NC score	0.094445 (rank : 503)	θ value	3.0926 (rank : 298)
Query Neighborhood Hits	362	Target Neighborhood Hits	211	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P0K1, O75075, O75076, Q9P0K2, Q9UIA1, Q9UKK2	Gene names	ADAM22, MDC2
Domain Architecture
Description	ADAM 22 precursor (A disintegrin and metalloproteinase domain 22) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2) (Metalloproteinase-disintegrin ADAM22-3).

ADAM7_MOUSE
NC score	0.094232 (rank : 504)	θ value	0.365318 (rank : 220)
Query Neighborhood Hits	362	Target Neighborhood Hits	200	Shared Neighborhood Hits	110
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

BMP1_MOUSE
NC score	0.094063 (rank : 505)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	78
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CNTP1_HUMAN
NC score	0.093990 (rank : 506)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	362	Target Neighborhood Hits	196	Shared Neighborhood Hits	64
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

LORI_MOUSE
NC score	0.093277 (rank : 507)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	P18165, Q8R0I9	Gene names	Lor
Domain Architecture	No domain graphic available
Description	Loricrin.

MMRN1_HUMAN
NC score	0.093146 (rank : 508)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	362	Target Neighborhood Hits	636	Shared Neighborhood Hits	73
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

BMP1_HUMAN
NC score	0.093015 (rank : 509)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	362	Target Neighborhood Hits	233	Shared Neighborhood Hits	77
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

ADA25_MOUSE
NC score	0.092996 (rank : 510)	θ value	0.62314 (rank : 237)
Query Neighborhood Hits	362	Target Neighborhood Hits	213	Shared Neighborhood Hits	110
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

CNTP1_MOUSE
NC score	0.092438 (rank : 511)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	362	Target Neighborhood Hits	183	Shared Neighborhood Hits	60
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

IDD_HUMAN
NC score	0.092359 (rank : 512)	θ value	0.47712 (rank : 230)
Query Neighborhood Hits	362	Target Neighborhood Hits	127	Shared Neighborhood Hits	36
SwissProt Accessions	P98153	Gene names	DGCR2, IDD, KIAA0163
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor.

PGCB_HUMAN
NC score	0.092309 (rank : 513)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	362	Target Neighborhood Hits	478	Shared Neighborhood Hits	93
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

ADA12_MOUSE
NC score	0.091966 (rank : 514)	θ value	6.88961 (rank : 330)
Query Neighborhood Hits	362	Target Neighborhood Hits	474	Shared Neighborhood Hits	100
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

MSMB_HUMAN
NC score	0.091911 (rank : 515)	θ value	1.06291 (rank : 252)
Query Neighborhood Hits	362	Target Neighborhood Hits	15	Shared Neighborhood Hits	13
SwissProt Accessions	P08118, P11999, Q13125, Q9UC59	Gene names	MSMB, PRSP
Domain Architecture
Description	Beta-microseminoprotein precursor (Prostate secreted seminal plasma protein) (Prostate secretory protein PSP94) (PSP-94) (Seminal plasma beta-inhibin) (Immunoglobulin-binding factor) (IGBF) (PN44).

PROP_HUMAN
NC score	0.090926 (rank : 516)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	P27918, O15134, O15135, O15136, O75826	Gene names	CFP, PFC
Domain Architecture
Description	Properdin precursor (Factor P).

MUC13_HUMAN
NC score	0.090581 (rank : 517)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	362	Target Neighborhood Hits	164	Shared Neighborhood Hits	64
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

LRP3_HUMAN
NC score	0.090346 (rank : 518)	θ value	6.88961 (rank : 339)
Query Neighborhood Hits	362	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ADA30_HUMAN
NC score	0.090188 (rank : 519)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	362	Target Neighborhood Hits	391	Shared Neighborhood Hits	95
SwissProt Accessions	Q9UKF2, Q9UKF1	Gene names	ADAM30
Domain Architecture
Description	ADAM 30 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 30).

SPON1_MOUSE
NC score	0.089994 (rank : 520)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	362	Target Neighborhood Hits	123	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VCC9, Q8K2Q8	Gene names	Spon1
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin).

TLL2_HUMAN
NC score	0.089551 (rank : 521)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	362	Target Neighborhood Hits	241	Shared Neighborhood Hits	81
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.089268 (rank : 522)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	362	Target Neighborhood Hits	237	Shared Neighborhood Hits	77
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.089093 (rank : 523)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	76
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

APR3_MOUSE
NC score	0.089052 (rank : 524)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	362	Target Neighborhood Hits	61	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

ADA32_MOUSE
NC score	0.089037 (rank : 525)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	125
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

CLC14_HUMAN
NC score	0.088954 (rank : 526)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	362	Target Neighborhood Hits	143	Shared Neighborhood Hits	54
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

SPON1_HUMAN
NC score	0.088143 (rank : 527)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	362	Target Neighborhood Hits	117	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HCB6, O94862, Q8NCD7, Q8WUR5	Gene names	SPON1, KIAA0762, VSGP
Domain Architecture	No domain graphic available
Description	Spondin-1 precursor (F-spondin) (Vascular smooth muscle cell growth- promoting factor).

ADA21_HUMAN
NC score	0.087913 (rank : 528)	θ value	3.0926 (rank : 297)
Query Neighborhood Hits	362	Target Neighborhood Hits	181	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UKJ8, O43507	Gene names	ADAM21
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21).

LRP10_MOUSE
NC score	0.087835 (rank : 529)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	362	Target Neighborhood Hits	169	Shared Neighborhood Hits	67
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

IBP6_MOUSE
NC score	0.087697 (rank : 530)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	23
SwissProt Accessions	P47880	Gene names	Igfbp6, Igfbp-6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

FA7_HUMAN
NC score	0.087517 (rank : 531)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	362	Target Neighborhood Hits	404	Shared Neighborhood Hits	108
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

ADM1B_MOUSE
NC score	0.087352 (rank : 532)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	362	Target Neighborhood Hits	236	Shared Neighborhood Hits	111
SwissProt Accessions	Q8R534, Q9R156	Gene names	Adam1b
Domain Architecture
Description	ADAM 1b precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1b) (Fertilin alpha 1b subunit).

ADA21_MOUSE
NC score	0.087289 (rank : 533)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	362	Target Neighborhood Hits	172	Shared Neighborhood Hits	90
SwissProt Accessions	Q9JI76	Gene names	Adam21, Adam31
Domain Architecture
Description	ADAM 21 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 21) (ADAM 31).

PROC_HUMAN
NC score	0.086059 (rank : 534)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	362	Target Neighborhood Hits	406	Shared Neighborhood Hits	114
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

IBP6_HUMAN
NC score	0.085879 (rank : 535)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	362	Target Neighborhood Hits	55	Shared Neighborhood Hits	27
SwissProt Accessions	P24592, Q14492	Gene names	IGFBP6, IBP6
Domain Architecture
Description	Insulin-like growth factor-binding protein 6 precursor (IGFBP-6) (IBP- 6) (IGF-binding protein 6).

LRP10_HUMAN
NC score	0.085814 (rank : 536)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	362	Target Neighborhood Hits	197	Shared Neighborhood Hits	66
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

NRG2_MOUSE
NC score	0.085631 (rank : 537)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	362	Target Neighborhood Hits	392	Shared Neighborhood Hits	64
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TLL2_MOUSE
NC score	0.085103 (rank : 538)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	362	Target Neighborhood Hits	240	Shared Neighborhood Hits	80
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

IDD_MOUSE
NC score	0.084856 (rank : 539)	θ value	0.62314 (rank : 240)
Query Neighborhood Hits	362	Target Neighborhood Hits	151	Shared Neighborhood Hits	37
SwissProt Accessions	P98154, Q61844	Gene names	Dgcr2, Dgsc, Idd, Sez-12, Sez12
Domain Architecture
Description	Integral membrane protein DGCR2/IDD precursor (Seizure-related membrane-bound adhesion protein).

FREM3_MOUSE
NC score	0.084796 (rank : 540)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	362	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FREM3_HUMAN
NC score	0.084697 (rank : 541)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	362	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

KRA32_HUMAN
NC score	0.084652 (rank : 542)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	362	Target Neighborhood Hits	51	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYR7	Gene names	KRTAP3-2, KAP3.2, KRTAP3.2
Domain Architecture
Description	Keratin-associated protein 3-2 (Keratin-associated protein 3.2) (High sulfur keratin-associated protein 3.2).

PAPPA_HUMAN
NC score	0.084549 (rank : 543)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	362	Target Neighborhood Hits	161	Shared Neighborhood Hits	57
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SMDF_HUMAN
NC score	0.084202 (rank : 544)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	362	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

CO8B_HUMAN
NC score	0.083591 (rank : 545)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	362	Target Neighborhood Hits	199	Shared Neighborhood Hits	59
SwissProt Accessions	P07358	Gene names	C8B
Domain Architecture
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

FSTL1_HUMAN
NC score	0.083040 (rank : 546)	θ value	2.36792 (rank : 283)
Query Neighborhood Hits	362	Target Neighborhood Hits	68	Shared Neighborhood Hits	25
SwissProt Accessions	Q12841	Gene names	FSTL1, FRP
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1).

NRG1_HUMAN
NC score	0.082932 (rank : 547)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	362	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

KRA33_HUMAN
NC score	0.082236 (rank : 548)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	362	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYR6, Q52LP0	Gene names	KRTAP3-3, KAP3.3, KRTAP3.3
Domain Architecture
Description	Keratin-associated protein 3-3 (Keratin-associated protein 3.3) (High sulfur keratin-associated protein 3.3).

ADAM2_HUMAN
NC score	0.082229 (rank : 549)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	362	Target Neighborhood Hits	175	Shared Neighborhood Hits	92
SwissProt Accessions	Q99965, P78326, Q9UQQ8	Gene names	ADAM2, FTNB
Domain Architecture
Description	ADAM 2 precursor (A disintegrin and metalloproteinase domain 2) (Fertilin subunit beta) (PH-30) (PH30).

CD320_HUMAN
NC score	0.081867 (rank : 550)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	362	Target Neighborhood Hits	103	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NPF0, Q53HF7	Gene names	CD320, 8D6A
Domain Architecture	No domain graphic available
Description	CD320 antigen precursor (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6).

TNR7_MOUSE
NC score	0.081169 (rank : 551)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	362	Target Neighborhood Hits	112	Shared Neighborhood Hits	56
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

APR3_HUMAN
NC score	0.081044 (rank : 552)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	36
SwissProt Accessions	Q6UW56, Q96FF6, Q96RT2, Q9Y2R7, Q9Y5L7	Gene names	APR3, C2orf28
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3) (p18).

CO8A_HUMAN
NC score	0.080717 (rank : 553)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	362	Target Neighborhood Hits	200	Shared Neighborhood Hits	65
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

TNR19_HUMAN
NC score	0.080425 (rank : 554)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	362	Target Neighborhood Hits	89	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS68, Q9BXZ9, Q9BY00, Q9NZV2	Gene names	TNFRSF19, TAJ, TROY
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

TNR11_HUMAN
NC score	0.080032 (rank : 555)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	362	Target Neighborhood Hits	135	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

CO7A1_HUMAN
NC score	0.079911 (rank : 556)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	362	Target Neighborhood Hits	807	Shared Neighborhood Hits	34
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

NRG4_HUMAN
NC score	0.079578 (rank : 557)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	362	Target Neighborhood Hits	85	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

HTRA2_MOUSE
NC score	0.079366 (rank : 558)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	362	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JIY5, Q9R108	Gene names	Htra2, Omi, Prss25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

AD26A_MOUSE
NC score	0.079313 (rank : 559)	θ value	0.0961366 (rank : 193)
Query Neighborhood Hits	362	Target Neighborhood Hits	165	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

TNR22_MOUSE
NC score	0.079254 (rank : 560)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	362	Target Neighborhood Hits	97	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

HTRA2_HUMAN
NC score	0.079124 (rank : 561)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	362	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4	Gene names	HTRA2, OMI, PRSS25
Domain Architecture
Description	Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).

RSPO1_MOUSE
NC score	0.079077 (rank : 562)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	362	Target Neighborhood Hits	85	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z132, Q3V1S3	Gene names	Rspo1
Domain Architecture	No domain graphic available
Description	R-spondin-1 precursor (Roof plate-specific spondin-1) (Cysteine-rich and single thrombospondin domain-containing protein 3) (Cristin-3) (mCristin-3).

EMR4_MOUSE
NC score	0.078353 (rank : 563)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	362	Target Neighborhood Hits	191	Shared Neighborhood Hits	58
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

FSTL1_MOUSE
NC score	0.078145 (rank : 564)	θ value	5.27518 (rank : 320)
Query Neighborhood Hits	362	Target Neighborhood Hits	74	Shared Neighborhood Hits	25
SwissProt Accessions	Q62356, Q99JI9	Gene names	Fstl1, Frp, Fstl, Tsc36
Domain Architecture
Description	Follistatin-related protein 1 precursor (Follistatin-like 1) (TGF- beta-inducible protein TSC-36).

FINC_MOUSE
NC score	0.077947 (rank : 565)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	362	Target Neighborhood Hits	309	Shared Neighborhood Hits	43
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

SPR2E_MOUSE
NC score	0.077613 (rank : 566)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	362	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

PGH2_MOUSE
NC score	0.077600 (rank : 567)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	362	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

CO8A_MOUSE
NC score	0.077176 (rank : 568)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	362	Target Neighborhood Hits	182	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K182, Q8CHJ9, Q8CHK1	Gene names	C8a
Domain Architecture	No domain graphic available
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

SPR2I_MOUSE
NC score	0.076990 (rank : 569)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	362	Target Neighborhood Hits	45	Shared Neighborhood Hits	15
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

ADA29_HUMAN
NC score	0.076562 (rank : 570)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	362	Target Neighborhood Hits	247	Shared Neighborhood Hits	85
SwissProt Accessions	Q9UKF5, Q9UHP1, Q9UKF3, Q9UKF4	Gene names	ADAM29
Domain Architecture
Description	ADAM 29 precursor (A disintegrin and metalloproteinase domain 29).

COKA1_HUMAN
NC score	0.076491 (rank : 571)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	362	Target Neighborhood Hits	403	Shared Neighborhood Hits	27
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

FREM1_HUMAN
NC score	0.076420 (rank : 572)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	362	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

SPR2H_MOUSE
NC score	0.075528 (rank : 573)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	362	Target Neighborhood Hits	82	Shared Neighborhood Hits	23
SwissProt Accessions	O70559	Gene names	Sprr2h
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2H.

PGH2_HUMAN
NC score	0.075170 (rank : 574)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	362	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

TRI42_MOUSE
NC score	0.074987 (rank : 575)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	362	Target Neighborhood Hits	316	Shared Neighborhood Hits	66
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

SPR2F_HUMAN
NC score	0.074818 (rank : 576)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	362	Target Neighborhood Hits	33	Shared Neighborhood Hits	14
SwissProt Accessions	Q96RM1	Gene names	SPRR2F
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F (SPR-2F).

MEP1A_MOUSE
NC score	0.074732 (rank : 577)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	362	Target Neighborhood Hits	166	Shared Neighborhood Hits	67
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

SPR2F_MOUSE
NC score	0.074604 (rank : 578)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

FINC_HUMAN
NC score	0.074564 (rank : 579)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	362	Target Neighborhood Hits	302	Shared Neighborhood Hits	39
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

NRG2_HUMAN
NC score	0.073548 (rank : 580)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	56
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

ATS9_HUMAN
NC score	0.073432 (rank : 581)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	362	Target Neighborhood Hits	219	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P2N4, Q9NR29	Gene names	ADAMTS9, KIAA1312
Domain Architecture
Description	ADAMTS-9 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 9) (ADAM-TS 9) (ADAM-TS9).

TNR3_MOUSE
NC score	0.073381 (rank : 582)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	362	Target Neighborhood Hits	113	Shared Neighborhood Hits	53
SwissProt Accessions	P50284	Gene names	Ltbr, Tnfcr, Tnfrsf3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor).

FREM1_MOUSE
NC score	0.073303 (rank : 583)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	362	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

TNR26_MOUSE
NC score	0.072463 (rank : 584)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	362	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	P83626	Gene names	Tnfrsf26, Tnfrh3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 26 precursor (TNF receptor homolog 3).

ASTN_HUMAN
NC score	0.071893 (rank : 585)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	362	Target Neighborhood Hits	105	Shared Neighborhood Hits	48
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

MFGM_HUMAN
NC score	0.071850 (rank : 586)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	362	Target Neighborhood Hits	150	Shared Neighborhood Hits	60
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

ASTN_MOUSE
NC score	0.071753 (rank : 587)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	362	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q61137, Q505A0, Q7TQG3, Q8CHH2	Gene names	Astn, Astn1, Kiaa0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor (Neuronal migration protein GC14).

COCA1_MOUSE
NC score	0.071612 (rank : 588)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	362	Target Neighborhood Hits	467	Shared Neighborhood Hits	25
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MEP1A_HUMAN
NC score	0.071303 (rank : 589)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	68
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

TINAL_MOUSE
NC score	0.070665 (rank : 590)	θ value	0.0113563 (rank : 165)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	18
SwissProt Accessions	Q99JR5, Q9EQT9	Gene names	Tinagl1, Arg1, Lcn7, Tinagl
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Androgen- regulated gene 1 protein) (Adrenocortical zonation factor 1) (AZ-1) (Tubulointerstitial nephritis antigen-related protein) (TARP).

PGH1_MOUSE
NC score	0.070323 (rank : 591)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	362	Target Neighborhood Hits	100	Shared Neighborhood Hits	45
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

BAI3_MOUSE
NC score	0.070314 (rank : 592)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	362	Target Neighborhood Hits	250	Shared Neighborhood Hits	49
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

COEA1_HUMAN
NC score	0.070187 (rank : 593)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	362	Target Neighborhood Hits	427	Shared Neighborhood Hits	24
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

ST14_MOUSE
NC score	0.070126 (rank : 594)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	116
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TNR11_MOUSE
NC score	0.070025 (rank : 595)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	54
SwissProt Accessions	O35305, Q8VCT7	Gene names	Tnfrsf11a, Rank
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR).

COCA1_HUMAN
NC score	0.069854 (rank : 596)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	362	Target Neighborhood Hits	458	Shared Neighborhood Hits	26
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

NRG4_MOUSE
NC score	0.069778 (rank : 597)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	362	Target Neighborhood Hits	79	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

TINAG_HUMAN
NC score	0.069616 (rank : 598)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	362	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UJW2, Q9UJW1, Q9ULZ4	Gene names	TINAG
Domain Architecture
Description	Tubulointerstitial nephritis antigen (TIN-Ag).

ZN330_HUMAN
NC score	0.069615 (rank : 599)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	362	Target Neighborhood Hits	83	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y3S2	Gene names	ZNF330, NOA36
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

CO1A2_HUMAN
NC score	0.069597 (rank : 600)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	362	Target Neighborhood Hits	329	Shared Neighborhood Hits	12
SwissProt Accessions	P08123, P02464, Q9UEB6, Q9UPH0	Gene names	COL1A2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

TNR19_MOUSE
NC score	0.069479 (rank : 601)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	362	Target Neighborhood Hits	100	Shared Neighborhood Hits	41
SwissProt Accessions	Q9JLL3, Q812G3, Q9JHF1, Q9JJH6, Q9JLL2, Q9QXW7	Gene names	Tnfrsf19, Taj, Troy
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19 precursor (Toxicity and JNK inducer) (TRADE).

BAI1_HUMAN
NC score	0.068954 (rank : 602)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	362	Target Neighborhood Hits	375	Shared Neighborhood Hits	45
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ST14_HUMAN
NC score	0.068761 (rank : 603)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	362	Target Neighborhood Hits	409	Shared Neighborhood Hits	109
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TNR6B_HUMAN
NC score	0.068753 (rank : 604)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	362	Target Neighborhood Hits	103	Shared Neighborhood Hits	47
SwissProt Accessions	O95407	Gene names	TNFRSF6B, DCR3, TR6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6B precursor (Decoy receptor for Fas ligand) (Decoy receptor 3) (DcR3) (M68).

COEA1_MOUSE
NC score	0.068524 (rank : 605)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	362	Target Neighborhood Hits	402	Shared Neighborhood Hits	23
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

TNR6_MOUSE
NC score	0.068394 (rank : 606)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	362	Target Neighborhood Hits	99	Shared Neighborhood Hits	48
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

BAI3_HUMAN
NC score	0.068363 (rank : 607)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	362	Target Neighborhood Hits	246	Shared Neighborhood Hits	46
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

EREG_HUMAN
NC score	0.068308 (rank : 608)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	362	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	O14944	Gene names	EREG
Domain Architecture	No domain graphic available
Description	Epiregulin precursor.

ZN330_MOUSE
NC score	0.068180 (rank : 609)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	362	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q922H9, Q8C389, Q8K2M4	Gene names	Znf330, Noa36, Zfp330
Domain Architecture	No domain graphic available
Description	Zinc finger protein 330 (Nucleolar cysteine-rich protein) (Nucleolar autoantigen 36).

CO1A2_MOUSE
NC score	0.067888 (rank : 610)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	362	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	Q01149, Q8CGA5	Gene names	Col1a2, Cola2
Domain Architecture
Description	Collagen alpha-2(I) chain precursor.

CO9_MOUSE
NC score	0.067877 (rank : 611)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	362	Target Neighborhood Hits	153	Shared Neighborhood Hits	55
SwissProt Accessions	P06683, Q91XA7	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor.

CO9_HUMAN
NC score	0.067606 (rank : 612)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	362	Target Neighborhood Hits	147	Shared Neighborhood Hits	54
SwissProt Accessions	P02748	Gene names	C9
Domain Architecture
Description	Complement component C9 precursor [Contains: Complement component C9a; Complement component C9b].

FA7_MOUSE
NC score	0.067454 (rank : 613)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	362	Target Neighborhood Hits	374	Shared Neighborhood Hits	88
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

PAPPA_MOUSE
NC score	0.066953 (rank : 614)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	362	Target Neighborhood Hits	153	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

SUSD2_MOUSE
NC score	0.066805 (rank : 615)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	362	Target Neighborhood Hits	104	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

TNR5_HUMAN
NC score	0.066071 (rank : 616)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	362	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P25942, Q9BYU0	Gene names	CD40, TNFRSF5
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 5 precursor (CD40L receptor) (B-cell surface antigen CD40) (CDw40) (Bp50).

ADA20_HUMAN
NC score	0.066066 (rank : 617)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	362	Target Neighborhood Hits	143	Shared Neighborhood Hits	68
SwissProt Accessions	O43506, Q9UKJ9	Gene names	ADAM20
Domain Architecture
Description	ADAM 20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 20).

BAI1_MOUSE
NC score	0.065927 (rank : 618)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	362	Target Neighborhood Hits	340	Shared Neighborhood Hits	40
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

ATS12_HUMAN
NC score	0.065920 (rank : 619)	θ value	0.0736092 (rank : 190)
Query Neighborhood Hits	362	Target Neighborhood Hits	251	Shared Neighborhood Hits	62
SwissProt Accessions	P58397, Q6UWL3	Gene names	ADAMTS12
Domain Architecture
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

VASN_HUMAN
NC score	0.065585 (rank : 620)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	362	Target Neighborhood Hits	449	Shared Neighborhood Hits	78
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

TNR3_HUMAN
NC score	0.065474 (rank : 621)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	362	Target Neighborhood Hits	145	Shared Neighborhood Hits	47
SwissProt Accessions	P36941	Gene names	LTBR, TNFCR, TNFRSF3
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 3 precursor (Lymphotoxin-beta receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor C receptor).

CO5A1_HUMAN
NC score	0.065102 (rank : 622)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	362	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

TSEAR_HUMAN
NC score	0.064127 (rank : 623)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	362	Target Neighborhood Hits	37	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WU66	Gene names	TSPEAR, C21orf29
Domain Architecture
Description	Protein TSPEAR precursor (TSP-EAR).

SUSD2_HUMAN
NC score	0.063899 (rank : 624)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	362	Target Neighborhood Hits	99	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

DKK3_MOUSE
NC score	0.063674 (rank : 625)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	362	Target Neighborhood Hits	83	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QUN9	Gene names	Dkk3
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3).

TINAL_HUMAN
NC score	0.063673 (rank : 626)	θ value	0.47712 (rank : 236)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	18
SwissProt Accessions	Q9GZM7, Q8TEJ9, Q8WZ23, Q96GZ4, Q96JW3	Gene names	TINAGL1, GIS5, LCN7, OLRG2, TINAGL
Domain Architecture	No domain graphic available
Description	Tubulointerstitial nephritis antigen-like precursor (Tubulointerstitial nephritis antigen-related protein) (TIN Ag-related protein) (TIN-Ag-RP) (Glucocorticoid-inducible protein 5) (Oxidized LDL-responsive gene 2 protein) (OLRG-2).

BAI2_MOUSE
NC score	0.063559 (rank : 627)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	362	Target Neighborhood Hits	323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

ATS20_MOUSE
NC score	0.063258 (rank : 628)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	362	Target Neighborhood Hits	225	Shared Neighborhood Hits	80
SwissProt Accessions	P59511	Gene names	Adamts20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

LRP12_HUMAN
NC score	0.063068 (rank : 629)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	362	Target Neighborhood Hits	205	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

CO5A1_MOUSE
NC score	0.062902 (rank : 630)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	362	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

SHBG_HUMAN
NC score	0.062846 (rank : 631)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	362	Target Neighborhood Hits	45	Shared Neighborhood Hits	16
SwissProt Accessions	P04278, P14689, Q16616	Gene names	SHBG
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP) (Testosterone-estrogen-binding globulin) (Testosterone-estradiol- binding globulin) (TeBG).

CO2A1_HUMAN
NC score	0.062627 (rank : 632)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	362	Target Neighborhood Hits	486	Shared Neighborhood Hits	8
SwissProt Accessions	P02458, Q12985, Q14009, Q14044, Q14046, Q14056, Q14058, Q16672, Q6LBY1, Q6LBY2, Q6LBY3, Q99227, Q9UE38, Q9UE39, Q9UE40, Q9UE41, Q9UE42, Q9UE43	Gene names	COL2A1
Domain Architecture
Description	Collagen alpha-1(II) chain precursor [Contains: Chondrocalcin].

BAI2_HUMAN
NC score	0.062613 (rank : 633)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	362	Target Neighborhood Hits	332	Shared Neighborhood Hits	38
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

TNR1B_HUMAN
NC score	0.062566 (rank : 634)	θ value	4.03905 (rank : 316)
Query Neighborhood Hits	362	Target Neighborhood Hits	127	Shared Neighborhood Hits	51
SwissProt Accessions	P20333, Q16042, Q6YI29, Q9UIH1	Gene names	TNFRSF1B, TNFBR, TNFR2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor) (CD120b antigen) (Etanercept) [Contains: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBPII) (TBP- 2)].

ATS12_MOUSE
NC score	0.062523 (rank : 635)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	362	Target Neighborhood Hits	220	Shared Neighborhood Hits	66
SwissProt Accessions	Q811B3, Q8BK92, Q8BKY1	Gene names	Adamts12
Domain Architecture	No domain graphic available
Description	ADAMTS-12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 12) (ADAM-TS 12) (ADAM-TS12).

COBA1_MOUSE
NC score	0.062396 (rank : 636)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	362	Target Neighborhood Hits	487	Shared Neighborhood Hits	19
SwissProt Accessions	Q61245, Q64047	Gene names	Col11a1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

VASN_MOUSE
NC score	0.062371 (rank : 637)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	362	Target Neighborhood Hits	426	Shared Neighborhood Hits	76
SwissProt Accessions	Q9CZT5, Q8BJJ0, Q8R2G5	Gene names	Vasn, Slitl2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

NEU1_MOUSE
NC score	0.061972 (rank : 638)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	362	Target Neighborhood Hits	64	Shared Neighborhood Hits	39
SwissProt Accessions	P35454	Gene names	Oxt
Domain Architecture
Description	Oxytocin-neurophysin 1 precursor (OT-NPI) [Contains: Oxytocin (Ocytocin); Neurophysin 1].

ATS20_HUMAN
NC score	0.061942 (rank : 639)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	362	Target Neighborhood Hits	192	Shared Neighborhood Hits	68
SwissProt Accessions	P59510	Gene names	ADAMTS20
Domain Architecture
Description	ADAMTS-20 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 20) (ADAM-TS 20) (ADAM-TS20).

FURIN_MOUSE
NC score	0.061757 (rank : 640)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	362	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	P23188	Gene names	Furin, Fur, Pcsk3
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme) (Prohormone convertase 3).

COBA1_HUMAN
NC score	0.061132 (rank : 641)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	362	Target Neighborhood Hits	491	Shared Neighborhood Hits	20
SwissProt Accessions	P12107, Q14034, Q9UIT4, Q9UIT5, Q9UIT6	Gene names	COL11A1
Domain Architecture
Description	Collagen alpha-1(XI) chain precursor.

SEM5B_MOUSE
NC score	0.061100 (rank : 642)	θ value	5.27518 (rank : 324)
Query Neighborhood Hits	362	Target Neighborhood Hits	190	Shared Neighborhood Hits	48
SwissProt Accessions	Q60519	Gene names	Sema5b, Semag, SemG
Domain Architecture
Description	Semaphorin-5B precursor (Semaphorin G) (Sema G).

ATS18_HUMAN
NC score	0.061097 (rank : 643)	θ value	0.0431538 (rank : 182)
Query Neighborhood Hits	362	Target Neighborhood Hits	169	Shared Neighborhood Hits	55
SwissProt Accessions	Q8TE60, Q6P4R5, Q6ZWJ9	Gene names	ADAMTS18, ADAMTS21
Domain Architecture
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

FURIN_HUMAN
NC score	0.061086 (rank : 644)	θ value	6.88961 (rank : 334)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	P09958, Q14336, Q6LBS3	Gene names	FURIN, FUR, PACE
Domain Architecture
Description	Furin precursor (EC 3.4.21.75) (Paired basic amino acid residue cleaving enzyme) (PACE) (Dibasic-processing enzyme).

SPY1_HUMAN
NC score	0.060494 (rank : 645)	θ value	0.21417 (rank : 215)
Query Neighborhood Hits	362	Target Neighborhood Hits	64	Shared Neighborhood Hits	35
SwissProt Accessions	O43609, Q6PNE0	Gene names	SPRY1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ATS16_HUMAN
NC score	0.060309 (rank : 646)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	362	Target Neighborhood Hits	208	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TE57, Q8IVE2	Gene names	ADAMTS16, KIAA2029
Domain Architecture
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

DKK3_HUMAN
NC score	0.060299 (rank : 647)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	362	Target Neighborhood Hits	74	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBP4, Q9ULB7	Gene names	DKK3, REIC
Domain Architecture
Description	Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3).

CO6A3_HUMAN
NC score	0.060067 (rank : 648)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	362	Target Neighborhood Hits	317	Shared Neighborhood Hits	20
SwissProt Accessions	P12111, Q16501	Gene names	COL6A3
Domain Architecture
Description	Collagen alpha-3(VI) chain precursor.

SHBG_MOUSE
NC score	0.059506 (rank : 649)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	362	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	P97497	Gene names	Shbg
Domain Architecture
Description	Sex hormone-binding globulin precursor (SHBG) (Sex steroid-binding protein) (SBP) (Testis-specific androgen-binding protein) (ABP).

SEM5A_HUMAN
NC score	0.059119 (rank : 650)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	362	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q13591, O60408, Q1RLL9	Gene names	SEMA5A, SEMAF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

ATL2_HUMAN
NC score	0.058934 (rank : 651)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	362	Target Neighborhood Hits	125	Shared Neighborhood Hits	41
SwissProt Accessions	Q86TH1, O60345	Gene names	ADAMTSL2, KIAA0605
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2).

LRP12_MOUSE
NC score	0.058890 (rank : 652)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	362	Target Neighborhood Hits	180	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

PGH1_HUMAN
NC score	0.058456 (rank : 653)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	362	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

KR151_HUMAN
NC score	0.058117 (rank : 654)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	362	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q3LI76	Gene names	KRTAP15-1, KAP15.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 15-1.

SEM5B_HUMAN
NC score	0.058029 (rank : 655)	θ value	6.88961 (rank : 342)
Query Neighborhood Hits	362	Target Neighborhood Hits	178	Shared Neighborhood Hits	45
SwissProt Accessions	Q9P283, Q6UY12	Gene names	SEMA5B, KIAA1445
Domain Architecture
Description	Semaphorin-5B precursor.

ATS16_MOUSE
NC score	0.057928 (rank : 656)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	362	Target Neighborhood Hits	179	Shared Neighborhood Hits	58
SwissProt Accessions	Q69Z28, Q8K206	Gene names	Adamts16, Kiaa2029
Domain Architecture	No domain graphic available
Description	ADAMTS-16 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 16) (ADAM-TS 16) (ADAM-TS16).

SPY1_MOUSE
NC score	0.057752 (rank : 657)	θ value	0.365318 (rank : 226)
Query Neighborhood Hits	362	Target Neighborhood Hits	57	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QXV9	Gene names	Spry1
Domain Architecture
Description	Sprouty homolog 1 (Spry-1).

ODFP_MOUSE
NC score	0.057528 (rank : 658)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	362	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q61999	Gene names	Odf1, Odfp
Domain Architecture
Description	Outer dense fiber protein.

PCSK4_HUMAN
NC score	0.057329 (rank : 659)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	362	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q6UW60, Q8IY88, Q9UF79	Gene names	PCSK4, PC4
Domain Architecture	No domain graphic available
Description	Proprotein convertase subtilisin/kexin type 4 precursor (EC 3.4.21.-) (Proprotein convertase PC4).

ATS13_MOUSE
NC score	0.057128 (rank : 660)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	362	Target Neighborhood Hits	227	Shared Neighborhood Hits	66
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATS7_HUMAN
NC score	0.056812 (rank : 661)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	362	Target Neighborhood Hits	169	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

MCSP_HUMAN
NC score	0.056508 (rank : 662)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	362	Target Neighborhood Hits	48	Shared Neighborhood Hits	26
SwissProt Accessions	P49901, Q96A42	Gene names	SMCP, MCS, MCSP
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

TNR1A_HUMAN
NC score	0.056506 (rank : 663)	θ value	3.0926 (rank : 303)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	33
SwissProt Accessions	P19438	Gene names	TNFRSF1A, TNFAR, TNFR1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55) (CD120a antigen) [Contains: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)].

ATL2_MOUSE
NC score	0.056391 (rank : 664)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	362	Target Neighborhood Hits	137	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

ALK1_HUMAN
NC score	0.056361 (rank : 665)	θ value	0.62314 (rank : 238)
Query Neighborhood Hits	362	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	P03973, P07757	Gene names	SLPI, WAP4, WFDC4
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (HUSI-1) (Seminal proteinase inhibitor) (Secretory leukocyte protease inhibitor) (BLPI) (Mucus proteinase inhibitor) (MPI) (WAP four-disulfide core domain protein 4) (Protease inhibitor WAP4).

ATS17_HUMAN
NC score	0.056286 (rank : 666)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	362	Target Neighborhood Hits	194	Shared Neighborhood Hits	56
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

TNR6_HUMAN
NC score	0.056002 (rank : 667)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	362	Target Neighborhood Hits	95	Shared Neighborhood Hits	47
SwissProt Accessions	P25445, Q14292, Q14293, Q14294, Q14295, Q16652, Q6SSE9	Gene names	FAS, APT1, FAS1, TNFRSF6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

ATS14_HUMAN
NC score	0.055940 (rank : 668)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	362	Target Neighborhood Hits	382	Shared Neighborhood Hits	59
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

SPR2E_HUMAN
NC score	0.055889 (rank : 669)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	362	Target Neighborhood Hits	32	Shared Neighborhood Hits	14
SwissProt Accessions	P22531, Q96RM2	Gene names	SPRR2E
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E (SPR-2E) (Small proline-rich protein II) (SPR-II).

TR10B_MOUSE
NC score	0.055877 (rank : 670)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	362	Target Neighborhood Hits	76	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QZM4, Q9JJL5, Q9JJL6	Gene names	Tnfrsf10b, Dr5, Killer
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 10B precursor (Death receptor 5) (MK).

GNPTA_HUMAN
NC score	0.055709 (rank : 671)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

WFDC5_HUMAN
NC score	0.055483 (rank : 672)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TCV5, Q6UWE4	Gene names	WFDC5, WAP1
Domain Architecture
Description	WAP four-disulfide core domain protein 5 precursor (Putative protease inhibitor WAP1).

ATL3_HUMAN
NC score	0.055451 (rank : 673)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	362	Target Neighborhood Hits	414	Shared Neighborhood Hits	58
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

GNPTA_MOUSE
NC score	0.054451 (rank : 674)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	362	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

CO6A1_HUMAN
NC score	0.054415 (rank : 675)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	362	Target Neighborhood Hits	264	Shared Neighborhood Hits	13
SwissProt Accessions	P12109, O00117, O00118, Q14040, Q14041, Q16258	Gene names	COL6A1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

ATS18_MOUSE
NC score	0.053907 (rank : 676)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	362	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	Q4VC17, Q8BZD1	Gene names	Adamts18
Domain Architecture	No domain graphic available
Description	ADAMTS-18 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 18) (ADAM-TS 18) (ADAM-TS18).

TNR21_MOUSE
NC score	0.053867 (rank : 677)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	362	Target Neighborhood Hits	108	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CP003_HUMAN
NC score	0.053582 (rank : 678)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	362	Target Neighborhood Hits	56	Shared Neighborhood Hits	21
SwissProt Accessions	O95177, O95176	Gene names	C16orf3
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf3.

MUC1_HUMAN
NC score	0.053147 (rank : 679)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	362	Target Neighborhood Hits	975	Shared Neighborhood Hits	26
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CO6A1_MOUSE
NC score	0.052898 (rank : 680)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	362	Target Neighborhood Hits	241	Shared Neighborhood Hits	12
SwissProt Accessions	Q04857	Gene names	Col6a1
Domain Architecture
Description	Collagen alpha-1(VI) chain precursor.

TNR1A_MOUSE
NC score	0.051952 (rank : 681)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	362	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P25118	Gene names	Tnfrsf1a, Tnfr-1, Tnfr1
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1A precursor (p60) (TNF-R1) (TNF-RI) (TNFR-I) (p55).

BTC_HUMAN
NC score	0.051827 (rank : 682)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	362	Target Neighborhood Hits	70	Shared Neighborhood Hits	36
SwissProt Accessions	P35070, Q96F48	Gene names	BTC
Domain Architecture	No domain graphic available
Description	Betacellulin precursor (BTC).

ATS1_MOUSE
NC score	0.051156 (rank : 683)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	362	Target Neighborhood Hits	158	Shared Neighborhood Hits	50
SwissProt Accessions	P97857, O54768	Gene names	Adamts1
Domain Architecture
Description	ADAMTS-1 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 1) (ADAM-TS 1) (ADAM-TS1).

ATS3_HUMAN
NC score	0.050940 (rank : 684)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	362	Target Neighborhood Hits	179	Shared Neighborhood Hits	54
SwissProt Accessions	O15072, Q9BXZ8	Gene names	ADAMTS3, KIAA0366
Domain Architecture
Description	ADAMTS-3 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 3) (ADAM-TS 3) (ADAM-TS3) (Procollagen II amino propeptide-processing enzyme) (Procollagen II N-proteinase) (PC II-NP).

ATS19_MOUSE
NC score	0.050732 (rank : 685)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	362	Target Neighborhood Hits	188	Shared Neighborhood Hits	48
SwissProt Accessions	P59509	Gene names	Adamts19
Domain Architecture
Description	ADAMTS-19 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 19) (ADAM-TS 19) (ADAM-TS19).

ATS6_HUMAN
NC score	0.050674 (rank : 686)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	362	Target Neighborhood Hits	141	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UKP5	Gene names	ADAMTS6
Domain Architecture
Description	ADAMTS-6 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 6) (ADAM-TS 6) (ADAM-TS6).

ATS13_HUMAN
NC score	0.050503 (rank : 687)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	362	Target Neighborhood Hits	238	Shared Neighborhood Hits	48
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

SEM5A_MOUSE
NC score	0.050376 (rank : 688)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	362	Target Neighborhood Hits	162	Shared Neighborhood Hits	32
SwissProt Accessions	Q62217	Gene names	Sema5a, Semaf, SemF
Domain Architecture
Description	Semaphorin-5A precursor (Semaphorin F) (Sema F).

CILP2_HUMAN
NC score	0.050317 (rank : 689)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	362	Target Neighborhood Hits	307	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

COBA2_HUMAN
NC score	0.050260 (rank : 690)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	362	Target Neighborhood Hits	408	Shared Neighborhood Hits	18
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

TNR18_HUMAN
NC score	0.050130 (rank : 691)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	362	Target Neighborhood Hits	55	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y5U5, O95851, Q9NYJ9	Gene names	TNFRSF18, AITR, GITR
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein) (Activation-inducible TNFR family receptor).

ALK1_MOUSE
NC score	0.048997 (rank : 692)	θ value	1.06291 (rank : 248)
Query Neighborhood Hits	362	Target Neighborhood Hits	43	Shared Neighborhood Hits	12
SwissProt Accessions	P97430, O09081, O09082	Gene names	Slpi
Domain Architecture
Description	Antileukoproteinase 1 precursor (ALP) (Secretory leukocyte protease inhibitor).

AMNLS_MOUSE
NC score	0.045655 (rank : 693)	θ value	0.813845 (rank : 243)
Query Neighborhood Hits	362	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q99JB7, Q5I0U1, Q99MP9	Gene names	Amn
Domain Architecture	No domain graphic available
Description	Amnionless protein precursor.

MLL3_MOUSE
NC score	0.044497 (rank : 694)	θ value	8.99809 (rank : 358)
Query Neighborhood Hits	362	Target Neighborhood Hits	1399	Shared Neighborhood Hits	72
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

EZH1_MOUSE
NC score	0.043146 (rank : 695)	θ value	2.36792 (rank : 282)
Query Neighborhood Hits	362	Target Neighborhood Hits	126	Shared Neighborhood Hits	47
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

THYG_HUMAN
NC score	0.042825 (rank : 696)	θ value	4.03905 (rank : 315)
Query Neighborhood Hits	362	Target Neighborhood Hits	154	Shared Neighborhood Hits	51
SwissProt Accessions	P01266, O15274, O43899, Q15593, Q15948, Q9NYR1, Q9NYR2, Q9UMZ0, Q9UNY3	Gene names	TG
Domain Architecture
Description	Thyroglobulin precursor.

EZH1_HUMAN
NC score	0.041878 (rank : 697)	θ value	2.36792 (rank : 281)
Query Neighborhood Hits	362	Target Neighborhood Hits	121	Shared Neighborhood Hits	42
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

ZC3H3_MOUSE
NC score	0.037764 (rank : 698)	θ value	0.0193708 (rank : 175)
Query Neighborhood Hits	362	Target Neighborhood Hits	188	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHP0, Q80X78	Gene names	Zc3h3, Kiaa0150, Zc3hdc3, Zfp623
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

MLL3_HUMAN
NC score	0.037436 (rank : 699)	θ value	8.99809 (rank : 357)
Query Neighborhood Hits	362	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

INSR_HUMAN
NC score	0.034093 (rank : 700)	θ value	0.0563607 (rank : 185)
Query Neighborhood Hits	362	Target Neighborhood Hits	963	Shared Neighborhood Hits	81
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

EZH2_MOUSE
NC score	0.032381 (rank : 701)	θ value	8.99809 (rank : 353)
Query Neighborhood Hits	362	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

INSR_MOUSE
NC score	0.032218 (rank : 702)	θ value	0.00665767 (rank : 151)
Query Neighborhood Hits	362	Target Neighborhood Hits	968	Shared Neighborhood Hits	74
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

VEGFD_HUMAN
NC score	0.031281 (rank : 703)	θ value	4.03905 (rank : 317)
Query Neighborhood Hits	362	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	O43915	Gene names	FIGF, VEGFD
Domain Architecture
Description	Vascular endothelial growth factor D precursor (VEGF-D) (c-fos-induced growth factor) (FIGF).

EZH2_HUMAN
NC score	0.030425 (rank : 704)	θ value	8.99809 (rank : 352)
Query Neighborhood Hits	362	Target Neighborhood Hits	84	Shared Neighborhood Hits	28
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

TNR18_MOUSE
NC score	0.026837 (rank : 705)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	362	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

IL9_MOUSE
NC score	0.025400 (rank : 706)	θ value	4.03905 (rank : 310)
Query Neighborhood Hits	362	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	P15247	Gene names	Il9
Domain Architecture
Description	Interleukin-9 precursor (IL-9) (T-cell growth factor P40) (P40 cytokine).

RFX5_HUMAN
NC score	0.017622 (rank : 707)	θ value	3.0926 (rank : 302)
Query Neighborhood Hits	362	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P48382	Gene names	RFX5
Domain Architecture
Description	DNA-binding protein RFX5 (Regulatory factor X subunit 5).

TRAF1_MOUSE
NC score	0.017556 (rank : 708)	θ value	2.36792 (rank : 294)
Query Neighborhood Hits	362	Target Neighborhood Hits	52	Shared Neighborhood Hits	8
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

LIGA_MOUSE
NC score	0.011750 (rank : 709)	θ value	5.27518 (rank : 322)
Query Neighborhood Hits	362	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q61211, Q3TDE0, Q3THV5, Q3TTP4, Q8C491, Q8CBF1, Q8CC17, Q8R1I9, Q8R3M5	Gene names	Lgtn
Domain Architecture	No domain graphic available
Description	Ligatin.

TRAF1_HUMAN
NC score	0.011699 (rank : 710)	θ value	5.27518 (rank : 326)
Query Neighborhood Hits	362	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

LYAG_HUMAN
NC score	0.011627 (rank : 711)	θ value	1.38821 (rank : 256)
Query Neighborhood Hits	362	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	P10253, Q14351, Q16302	Gene names	GAA
Domain Architecture
Description	Lysosomal alpha-glucosidase precursor (EC 3.2.1.20) (Acid maltase) (Aglucosidase alfa) [Contains: 76 kDa lysosomal alpha-glucosidase; 70 kDa lysosomal alpha-glucosidase].

EPHA2_MOUSE
NC score	0.011592 (rank : 712)	θ value	8.99809 (rank : 351)
Query Neighborhood Hits	362	Target Neighborhood Hits	1020	Shared Neighborhood Hits	66
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

PLXB3_MOUSE
NC score	0.010482 (rank : 713)	θ value	2.36792 (rank : 291)
Query Neighborhood Hits	362	Target Neighborhood Hits	94	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QY40, Q80TH8	Gene names	Plxnb3, Kiaa1206, Plxn6
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor (Plexin-6).

KIME_MOUSE
NC score	0.010413 (rank : 714)	θ value	6.88961 (rank : 337)
Query Neighborhood Hits	362	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R008	Gene names	Mvk
Domain Architecture
Description	Mevalonate kinase (EC 2.7.1.36) (MK).

PLXB3_HUMAN
NC score	0.009005 (rank : 715)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	362	Target Neighborhood Hits	106	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ULL4, Q9HDA4	Gene names	PLXNB3, KIAA1206
Domain Architecture	No domain graphic available
Description	Plexin-B3 precursor.

RP1L1_MOUSE
NC score	0.008987 (rank : 716)	θ value	6.88961 (rank : 341)
Query Neighborhood Hits	362	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

UHRF1_MOUSE
NC score	0.008446 (rank : 717)	θ value	1.81305 (rank : 278)
Query Neighborhood Hits	362	Target Neighborhood Hits	278	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UBP54_HUMAN
NC score	0.008426 (rank : 718)	θ value	5.27518 (rank : 327)
Query Neighborhood Hits	362	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q70EL1, Q5F2F4	Gene names	USP54, C10orf29
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin- specific peptidase 54).

JHD1A_MOUSE
NC score	0.007680 (rank : 719)	θ value	6.88961 (rank : 336)
Query Neighborhood Hits	362	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

PRG4_HUMAN
NC score	0.007517 (rank : 720)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	362	Target Neighborhood Hits	764	Shared Neighborhood Hits	30
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

JHD1A_HUMAN
NC score	0.006766 (rank : 721)	θ value	8.99809 (rank : 356)
Query Neighborhood Hits	362	Target Neighborhood Hits	133	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

V2R1B_MOUSE
NC score	0.004749 (rank : 722)	θ value	5.27518 (rank : 328)
Query Neighborhood Hits	362	Target Neighborhood Hits	39	Shared Neighborhood Hits	6
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

EPHB3_HUMAN
NC score	0.004710 (rank : 723)	θ value	3.0926 (rank : 300)
Query Neighborhood Hits	362	Target Neighborhood Hits	996	Shared Neighborhood Hits	43
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

DPOLZ_HUMAN
NC score	0.003656 (rank : 724)	θ value	8.99809 (rank : 350)
Query Neighborhood Hits	362	Target Neighborhood Hits	200	Shared Neighborhood Hits	2
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

AT11A_MOUSE
NC score	0.002405 (rank : 725)	θ value	4.03905 (rank : 305)
Query Neighborhood Hits	362	Target Neighborhood Hits	77	Shared Neighborhood Hits	2
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

KCNC3_MOUSE
NC score	0.002326 (rank : 726)	θ value	2.36792 (rank : 286)
Query Neighborhood Hits	362	Target Neighborhood Hits	173	Shared Neighborhood Hits	2
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

ZN597_HUMAN
NC score	-0.010467 (rank : 727)	θ value	2.36792 (rank : 295)
Query Neighborhood Hits	362	Target Neighborhood Hits	722	Shared Neighborhood Hits	3
SwissProt Accessions	Q96LX8	Gene names	ZNF597
Domain Architecture	No domain graphic available
Description	Zinc finger protein 597.

ZN502_HUMAN
NC score	-0.010806 (rank : 728)	θ value	5.27518 (rank : 329)
Query Neighborhood Hits	362	Target Neighborhood Hits	762	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TBZ5	Gene names	ZNF502
Domain Architecture	No domain graphic available
Description	Zinc finger protein 502.