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Network neighborhood for query Sequence : EZH1_HUMAN

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EZH1_HUMAN
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EZH1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	121	Target Neighborhood Hits	121	Shared Neighborhood Hits	121
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	0 (rank : 2)	NC score	0.998109 (rank : 2)
Query Neighborhood Hits	121	Target Neighborhood Hits	126	Shared Neighborhood Hits	108
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	0 (rank : 3)	NC score	0.988594 (rank : 3)
Query Neighborhood Hits	121	Target Neighborhood Hits	84	Shared Neighborhood Hits	53
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	0 (rank : 4)	NC score	0.988237 (rank : 4)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SUV91_HUMAN
θ value	2.43343e-21 (rank : 5)	NC score	0.702841 (rank : 5)
Query Neighborhood Hits	121	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	2.43343e-21 (rank : 6)	NC score	0.696594 (rank : 6)
Query Neighborhood Hits	121	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

HRX_HUMAN
θ value	3.17815e-21 (rank : 7)	NC score	0.555914 (rank : 15)
Query Neighborhood Hits	121	Target Neighborhood Hits	825	Shared Neighborhood Hits	38
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SET1A_HUMAN
θ value	4.58923e-20 (rank : 8)	NC score	0.612885 (rank : 10)
Query Neighborhood Hits	121	Target Neighborhood Hits	690	Shared Neighborhood Hits	33
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NSD1_HUMAN
θ value	5.99374e-20 (rank : 9)	NC score	0.564428 (rank : 13)
Query Neighborhood Hits	121	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SETD2_HUMAN
θ value	7.82807e-20 (rank : 10)	NC score	0.651921 (rank : 9)
Query Neighborhood Hits	121	Target Neighborhood Hits	412	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SUV92_HUMAN
θ value	7.82807e-20 (rank : 11)	NC score	0.691193 (rank : 7)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

NSD1_MOUSE
θ value	1.33526e-19 (rank : 12)	NC score	0.561693 (rank : 14)
Query Neighborhood Hits	121	Target Neighborhood Hits	472	Shared Neighborhood Hits	39
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MLL3_HUMAN
θ value	3.88503e-19 (rank : 13)	NC score	0.415198 (rank : 22)
Query Neighborhood Hits	121	Target Neighborhood Hits	1644	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	3.88503e-19 (rank : 14)	NC score	0.437011 (rank : 20)
Query Neighborhood Hits	121	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SUV92_MOUSE
θ value	3.88503e-19 (rank : 15)	NC score	0.684997 (rank : 8)
Query Neighborhood Hits	121	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

MLL4_HUMAN
θ value	5.07402e-19 (rank : 16)	NC score	0.537792 (rank : 16)
Query Neighborhood Hits	121	Target Neighborhood Hits	722	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL2_HUMAN
θ value	1.13037e-18 (rank : 17)	NC score	0.422613 (rank : 21)
Query Neighborhood Hits	121	Target Neighborhood Hits	1788	Shared Neighborhood Hits	49
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

EHMT2_MOUSE
θ value	5.60996e-18 (rank : 18)	NC score	0.341415 (rank : 24)
Query Neighborhood Hits	121	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_HUMAN
θ value	1.24977e-17 (rank : 19)	NC score	0.343227 (rank : 23)
Query Neighborhood Hits	121	Target Neighborhood Hits	498	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
θ value	2.7842e-17 (rank : 20)	NC score	0.334046 (rank : 25)
Query Neighborhood Hits	121	Target Neighborhood Hits	417	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SETD8_HUMAN
θ value	1.47974e-10 (rank : 21)	NC score	0.611168 (rank : 11)
Query Neighborhood Hits	121	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	1.47974e-10 (rank : 22)	NC score	0.610503 (rank : 12)
Query Neighborhood Hits	121	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETB1_MOUSE
θ value	1.29631e-06 (rank : 23)	NC score	0.474638 (rank : 18)
Query Neighborhood Hits	121	Target Neighborhood Hits	150	Shared Neighborhood Hits	27
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
θ value	2.21117e-06 (rank : 24)	NC score	0.469558 (rank : 19)
Query Neighborhood Hits	121	Target Neighborhood Hits	141	Shared Neighborhood Hits	26
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB2_HUMAN
θ value	8.40245e-06 (rank : 25)	NC score	0.509735 (rank : 17)
Query Neighborhood Hits	121	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETD7_MOUSE
θ value	0.00175202 (rank : 26)	NC score	0.207438 (rank : 26)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD7_HUMAN
θ value	0.00298849 (rank : 27)	NC score	0.201830 (rank : 27)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

PTMA_HUMAN
θ value	0.125558 (rank : 28)	NC score	0.133721 (rank : 29)
Query Neighborhood Hits	121	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

ITB2_MOUSE
θ value	0.163984 (rank : 29)	NC score	0.036853 (rank : 106)
Query Neighborhood Hits	121	Target Neighborhood Hits	326	Shared Neighborhood Hits	29
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KRA53_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.084501 (rank : 36)
Query Neighborhood Hits	121	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA58_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.100161 (rank : 31)
Query Neighborhood Hits	121	Target Neighborhood Hits	324	Shared Neighborhood Hits	36
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

MCSP_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.158880 (rank : 28)
Query Neighborhood Hits	121	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

PZRN3_MOUSE
θ value	0.21417 (rank : 33)	NC score	0.026737 (rank : 123)
Query Neighborhood Hits	121	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

KRA44_HUMAN
θ value	0.279714 (rank : 34)	NC score	0.065811 (rank : 54)
Query Neighborhood Hits	121	Target Neighborhood Hits	162	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

NOTC2_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.042842 (rank : 96)
Query Neighborhood Hits	121	Target Neighborhood Hits	1113	Shared Neighborhood Hits	56
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KRA45_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.061230 (rank : 61)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KIF4A_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.017720 (rank : 134)
Query Neighborhood Hits	121	Target Neighborhood Hits	1159	Shared Neighborhood Hits	26
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NCOR1_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.046268 (rank : 93)
Query Neighborhood Hits	121	Target Neighborhood Hits	577	Shared Neighborhood Hits	17
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

TNR7_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.046799 (rank : 91)
Query Neighborhood Hits	121	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

ZAN_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.045559 (rank : 94)
Query Neighborhood Hits	121	Target Neighborhood Hits	808	Shared Neighborhood Hits	51
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA24_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.082295 (rank : 40)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

NP1L1_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.030665 (rank : 114)
Query Neighborhood Hits	121	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	P28656, Q3UL14	Gene names	Nap1l1, Nrp
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (Brain protein DN38).

PTMA_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.097708 (rank : 32)
Query Neighborhood Hits	121	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

CCD16_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.039458 (rank : 101)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

NCOR2_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.053900 (rank : 79)
Query Neighborhood Hits	121	Target Neighborhood Hits	870	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

NOTC2_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.038877 (rank : 102)
Query Neighborhood Hits	121	Target Neighborhood Hits	1069	Shared Neighborhood Hits	52
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PZRN3_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.022621 (rank : 128)
Query Neighborhood Hits	121	Target Neighborhood Hits	461	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

ROCK2_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.000313 (rank : 160)
Query Neighborhood Hits	121	Target Neighborhood Hits	2073	Shared Neighborhood Hits	19
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SEPP1_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.035366 (rank : 108)
Query Neighborhood Hits	121	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P49908, Q6PD59, Q6PI43, Q6PI87, Q6PJF9	Gene names	SEPP1, SELP
Domain Architecture
Description	Selenoprotein P precursor (SeP).

STAB2_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.025837 (rank : 124)
Query Neighborhood Hits	121	Target Neighborhood Hits	528	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TRIO_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.001533 (rank : 159)
Query Neighborhood Hits	121	Target Neighborhood Hits	1580	Shared Neighborhood Hits	14
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

KR102_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.048079 (rank : 89)
Query Neighborhood Hits	121	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA93_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.047527 (rank : 90)
Query Neighborhood Hits	121	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

SMYD3_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.070181 (rank : 48)
Query Neighborhood Hits	121	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TARA_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.039512 (rank : 100)
Query Neighborhood Hits	121	Target Neighborhood Hits	1626	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CRIM1_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.041878 (rank : 98)
Query Neighborhood Hits	121	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

ITB1_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.038706 (rank : 103)
Query Neighborhood Hits	121	Target Neighborhood Hits	298	Shared Neighborhood Hits	30
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ZNFX1_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.052236 (rank : 82)
Query Neighborhood Hits	121	Target Neighborhood Hits	407	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ITB2_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.030174 (rank : 116)
Query Neighborhood Hits	121	Target Neighborhood Hits	282	Shared Neighborhood Hits	26
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

KR511_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.094522 (rank : 33)
Query Neighborhood Hits	121	Target Neighborhood Hits	231	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA59_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.066334 (rank : 51)
Query Neighborhood Hits	121	Target Neighborhood Hits	310	Shared Neighborhood Hits	39
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA94_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.052886 (rank : 80)
Query Neighborhood Hits	121	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

NCOR2_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.046678 (rank : 92)
Query Neighborhood Hits	121	Target Neighborhood Hits	790	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NOTC1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.034805 (rank : 110)
Query Neighborhood Hits	121	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NRDC_MOUSE
θ value	3.0926 (rank : 65)	NC score	0.015735 (rank : 138)
Query Neighborhood Hits	121	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

SREC2_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.031960 (rank : 112)
Query Neighborhood Hits	121	Target Neighborhood Hits	645	Shared Neighborhood Hits	50
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

TAF5_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.007854 (rank : 148)
Query Neighborhood Hits	121	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
θ value	3.0926 (rank : 68)	NC score	0.006624 (rank : 149)
Query Neighborhood Hits	121	Target Neighborhood Hits	366	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

VWF_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.035191 (rank : 109)
Query Neighborhood Hits	121	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

ACY3_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.021242 (rank : 131)
Query Neighborhood Hits	121	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HD9	Gene names	ACY3, ASPA2
Domain Architecture
Description	Aspartoacylase-2 (EC 3.5.1.15) (Aminoacylase-3) (ACY-3) (Acylase III) (Hepatitis C virus core-binding protein 1) (HCBP1).

AFF1_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.016191 (rank : 137)
Query Neighborhood Hits	121	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

KR101_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.038353 (rank : 104)
Query Neighborhood Hits	121	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR103_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.050630 (rank : 84)
Query Neighborhood Hits	121	Target Neighborhood Hits	212	Shared Neighborhood Hits	36
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR105_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.055841 (rank : 72)
Query Neighborhood Hits	121	Target Neighborhood Hits	271	Shared Neighborhood Hits	40
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

RYR1_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.012783 (rank : 140)
Query Neighborhood Hits	121	Target Neighborhood Hits	303	Shared Neighborhood Hits	6
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

SMYD3_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.070677 (rank : 46)
Query Neighborhood Hits	121	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TARA_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.028826 (rank : 121)
Query Neighborhood Hits	121	Target Neighborhood Hits	1133	Shared Neighborhood Hits	24
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TRI42_HUMAN
θ value	4.03905 (rank : 78)	NC score	0.018760 (rank : 132)
Query Neighborhood Hits	121	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

BSN_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.028359 (rank : 122)
Query Neighborhood Hits	121	Target Neighborhood Hits	1537	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	5.27518 (rank : 80)	NC score	0.037786 (rank : 105)
Query Neighborhood Hits	121	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CCD16_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.023255 (rank : 126)
Query Neighborhood Hits	121	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

CFDP1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.021982 (rank : 130)
Query Neighborhood Hits	121	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UEE9, O00393, O00404, Q9UEF0, Q9UEF1, Q9UEF8	Gene names	CFDP1, BCNT
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur).

KRA57_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.073172 (rank : 45)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA98_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.044140 (rank : 95)
Query Neighborhood Hits	121	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

MYSM1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.032156 (rank : 111)
Query Neighborhood Hits	121	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

NUCL_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.004667 (rank : 153)
Query Neighborhood Hits	121	Target Neighborhood Hits	415	Shared Neighborhood Hits	6
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

SSPO_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.031773 (rank : 113)
Query Neighborhood Hits	121	Target Neighborhood Hits	800	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB2_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.022195 (rank : 129)
Query Neighborhood Hits	121	Target Neighborhood Hits	534	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

VEGFC_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.028847 (rank : 120)
Query Neighborhood Hits	121	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ZNF31_HUMAN
θ value	5.27518 (rank : 90)	NC score	-0.003063 (rank : 162)
Query Neighborhood Hits	121	Target Neighborhood Hits	769	Shared Neighborhood Hits	3
SwissProt Accessions	P17040, Q96H84	Gene names	ZNF31, KOX29, ZNF360, ZSCAN20
Domain Architecture	No domain graphic available
Description	Zinc finger protein 31 (Zinc finger protein KOX29) (Zinc finger and SCAN domain-containing protein 20) (Zinc finger protein 360).

AP3B2_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.010531 (rank : 143)
Query Neighborhood Hits	121	Target Neighborhood Hits	246	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CSTN2_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.004211 (rank : 154)
Query Neighborhood Hits	121	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ER65	Gene names	Clstn2, Cs2, Cstn2
Domain Architecture
Description	Calsyntenin-2 precursor.

KR109_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.039637 (rank : 99)
Query Neighborhood Hits	121	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

LUM_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.002493 (rank : 157)
Query Neighborhood Hits	121	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

MEGF6_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.022939 (rank : 127)
Query Neighborhood Hits	121	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MUC5B_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.036590 (rank : 107)
Query Neighborhood Hits	121	Target Neighborhood Hits	1020	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYST4_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.068366 (rank : 49)
Query Neighborhood Hits	121	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

ROCK2_MOUSE
θ value	6.88961 (rank : 98)	NC score	-0.001705 (rank : 161)
Query Neighborhood Hits	121	Target Neighborhood Hits	2072	Shared Neighborhood Hits	16
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

SCN2A_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.004077 (rank : 155)
Query Neighborhood Hits	121	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SMCA2_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.006496 (rank : 150)
Query Neighborhood Hits	121	Target Neighborhood Hits	503	Shared Neighborhood Hits	12
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SREC2_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.029947 (rank : 117)
Query Neighborhood Hits	121	Target Neighborhood Hits	605	Shared Neighborhood Hits	52
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

TAIP2_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.008069 (rank : 147)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P59055	Gene names	Taip2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

TECT2_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.014465 (rank : 139)
Query Neighborhood Hits	121	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q2MV57, Q6PDZ5, Q8C0B3, Q9CXF5	Gene names	Tect2
Domain Architecture	No domain graphic available
Description	Tectonic-2 precursor.

ZNFX1_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.049953 (rank : 88)
Query Neighborhood Hits	121	Target Neighborhood Hits	308	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CC019_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.008757 (rank : 146)
Query Neighborhood Hits	121	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PII3, Q96CS5	Gene names	C3orf19
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf19.

CDR1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.029367 (rank : 119)
Query Neighborhood Hits	121	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P51861	Gene names	CDR1
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related antigen 1 (CDR34).

CE152_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.004018 (rank : 156)
Query Neighborhood Hits	121	Target Neighborhood Hits	976	Shared Neighborhood Hits	11
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CS1A_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.001669 (rank : 158)
Query Neighborhood Hits	121	Target Neighborhood Hits	360	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CYLC1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.010102 (rank : 145)
Query Neighborhood Hits	121	Target Neighborhood Hits	408	Shared Neighborhood Hits	7
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

HTRA3_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.012086 (rank : 141)
Query Neighborhood Hits	121	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.011623 (rank : 142)
Query Neighborhood Hits	121	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

KIF4A_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.010362 (rank : 144)
Query Neighborhood Hits	121	Target Neighborhood Hits	1033	Shared Neighborhood Hits	22
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KR10B_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.042302 (rank : 97)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

NCOR1_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.030443 (rank : 115)
Query Neighborhood Hits	121	Target Neighborhood Hits	521	Shared Neighborhood Hits	12
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NOTC1_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.029879 (rank : 118)
Query Neighborhood Hits	121	Target Neighborhood Hits	916	Shared Neighborhood Hits	44
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NP1L1_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.017137 (rank : 135)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	P55209	Gene names	NAP1L1, NRP
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP).

SPY2_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.016673 (rank : 136)
Query Neighborhood Hits	121	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

SPY2_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.017747 (rank : 133)
Query Neighborhood Hits	121	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

TNR7_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.025014 (rank : 125)
Query Neighborhood Hits	121	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

WNT1_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.004920 (rank : 152)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P04628	Gene names	WNT1, INT1
Domain Architecture
Description	Proto-oncogene protein Wnt-1 precursor.

WNT1_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.004921 (rank : 151)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P04426	Gene names	Wnt1, Int-1, Wnt-1
Domain Architecture
Description	Proto-oncogene protein Wnt-1 precursor.

AIRE_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.063694 (rank : 60)
Query Neighborhood Hits	121	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.066023 (rank : 52)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CBX1_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.057697 (rank : 69)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.057697 (rank : 70)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.059231 (rank : 67)
Query Neighborhood Hits	121	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.059817 (rank : 65)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.054799 (rank : 74)
Query Neighborhood Hits	121	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.054494 (rank : 78)
Query Neighborhood Hits	121	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

DPF1_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.075289 (rank : 43)
Query Neighborhood Hits	121	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.066502 (rank : 50)
Query Neighborhood Hits	121	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

K1333_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.064635 (rank : 57)
Query Neighborhood Hits	121	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.064619 (rank : 58)
Query Neighborhood Hits	121	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

LCE1C_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.050670 (rank : 83)
Query Neighborhood Hits	121	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.063697 (rank : 59)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.060890 (rank : 63)
Query Neighborhood Hits	121	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

MDC1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.050454 (rank : 85)
Query Neighborhood Hits	121	Target Neighborhood Hits	1446	Shared Neighborhood Hits	28
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYST3_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.056384 (rank : 71)
Query Neighborhood Hits	121	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.058437 (rank : 68)
Query Neighborhood Hits	121	Target Neighborhood Hits	688	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.061172 (rank : 62)
Query Neighborhood Hits	121	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.060008 (rank : 64)
Query Neighborhood Hits	121	Target Neighborhood Hits	303	Shared Neighborhood Hits	11
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.059267 (rank : 66)
Query Neighborhood Hits	121	Target Neighborhood Hits	285	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.050036 (rank : 87)
Query Neighborhood Hits	121	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.054688 (rank : 76)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.084830 (rank : 35)
Query Neighborhood Hits	121	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.083252 (rank : 39)
Query Neighborhood Hits	121	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.113410 (rank : 30)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF12_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.054632 (rank : 77)
Query Neighborhood Hits	121	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.054708 (rank : 75)
Query Neighborhood Hits	121	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF6_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.086731 (rank : 34)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.084251 (rank : 38)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.070541 (rank : 47)
Query Neighborhood Hits	121	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.065634 (rank : 55)
Query Neighborhood Hits	121	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RAI1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.078234 (rank : 41)
Query Neighborhood Hits	121	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.084479 (rank : 37)
Query Neighborhood Hits	121	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REQU_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.065921 (rank : 53)
Query Neighborhood Hits	121	Target Neighborhood Hits	523	Shared Neighborhood Hits	9
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.065455 (rank : 56)
Query Neighborhood Hits	121	Target Neighborhood Hits	519	Shared Neighborhood Hits	9
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

TCF20_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.077877 (rank : 42)
Query Neighborhood Hits	121	Target Neighborhood Hits	323	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.074775 (rank : 44)
Query Neighborhood Hits	121	Target Neighborhood Hits	396	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

UHRF1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.052251 (rank : 81)
Query Neighborhood Hits	121	Target Neighborhood Hits	272	Shared Neighborhood Hits	10
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.055055 (rank : 73)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.050180 (rank : 86)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

Hits sorted by NC score

EZH1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	121	Target Neighborhood Hits	121	Shared Neighborhood Hits	121
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.998109 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	121	Target Neighborhood Hits	126	Shared Neighborhood Hits	108
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
NC score	0.988594 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	121	Target Neighborhood Hits	84	Shared Neighborhood Hits	53
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.988237 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	121	Target Neighborhood Hits	86	Shared Neighborhood Hits	53
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SUV91_HUMAN
NC score	0.702841 (rank : 5)	θ value	2.43343e-21 (rank : 5)
Query Neighborhood Hits	121	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
NC score	0.696594 (rank : 6)	θ value	2.43343e-21 (rank : 6)
Query Neighborhood Hits	121	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.691193 (rank : 7)	θ value	7.82807e-20 (rank : 11)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
NC score	0.684997 (rank : 8)	θ value	3.88503e-19 (rank : 15)
Query Neighborhood Hits	121	Target Neighborhood Hits	59	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SETD2_HUMAN
NC score	0.651921 (rank : 9)	θ value	7.82807e-20 (rank : 10)
Query Neighborhood Hits	121	Target Neighborhood Hits	412	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SET1A_HUMAN
NC score	0.612885 (rank : 10)	θ value	4.58923e-20 (rank : 8)
Query Neighborhood Hits	121	Target Neighborhood Hits	690	Shared Neighborhood Hits	33
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_HUMAN
NC score	0.611168 (rank : 11)	θ value	1.47974e-10 (rank : 21)
Query Neighborhood Hits	121	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
NC score	0.610503 (rank : 12)	θ value	1.47974e-10 (rank : 22)
Query Neighborhood Hits	121	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

NSD1_HUMAN
NC score	0.564428 (rank : 13)	θ value	5.99374e-20 (rank : 9)
Query Neighborhood Hits	121	Target Neighborhood Hits	427	Shared Neighborhood Hits	35
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
NC score	0.561693 (rank : 14)	θ value	1.33526e-19 (rank : 12)
Query Neighborhood Hits	121	Target Neighborhood Hits	472	Shared Neighborhood Hits	39
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

HRX_HUMAN
NC score	0.555914 (rank : 15)	θ value	3.17815e-21 (rank : 7)
Query Neighborhood Hits	121	Target Neighborhood Hits	825	Shared Neighborhood Hits	38
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
NC score	0.537792 (rank : 16)	θ value	5.07402e-19 (rank : 16)
Query Neighborhood Hits	121	Target Neighborhood Hits	722	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SETB2_HUMAN
NC score	0.509735 (rank : 17)	θ value	8.40245e-06 (rank : 25)
Query Neighborhood Hits	121	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.474638 (rank : 18)	θ value	1.29631e-06 (rank : 23)
Query Neighborhood Hits	121	Target Neighborhood Hits	150	Shared Neighborhood Hits	27
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.469558 (rank : 19)	θ value	2.21117e-06 (rank : 24)
Query Neighborhood Hits	121	Target Neighborhood Hits	141	Shared Neighborhood Hits	26
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

MLL3_MOUSE
NC score	0.437011 (rank : 20)	θ value	3.88503e-19 (rank : 14)
Query Neighborhood Hits	121	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.422613 (rank : 21)	θ value	1.13037e-18 (rank : 17)
Query Neighborhood Hits	121	Target Neighborhood Hits	1788	Shared Neighborhood Hits	49
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.415198 (rank : 22)	θ value	3.88503e-19 (rank : 13)
Query Neighborhood Hits	121	Target Neighborhood Hits	1644	Shared Neighborhood Hits	57
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EHMT2_HUMAN
NC score	0.343227 (rank : 23)	θ value	1.24977e-17 (rank : 19)
Query Neighborhood Hits	121	Target Neighborhood Hits	498	Shared Neighborhood Hits	34
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.341415 (rank : 24)	θ value	5.60996e-18 (rank : 18)
Query Neighborhood Hits	121	Target Neighborhood Hits	750	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.334046 (rank : 25)	θ value	2.7842e-17 (rank : 20)
Query Neighborhood Hits	121	Target Neighborhood Hits	417	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SETD7_MOUSE
NC score	0.207438 (rank : 26)	θ value	0.00175202 (rank : 26)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD7_HUMAN
NC score	0.201830 (rank : 27)	θ value	0.00298849 (rank : 27)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	15
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

MCSP_MOUSE
NC score	0.158880 (rank : 28)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	121	Target Neighborhood Hits	108	Shared Neighborhood Hits	19
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

PTMA_HUMAN
NC score	0.133721 (rank : 29)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	121	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PHF11_HUMAN
NC score	0.113410 (rank : 30)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

KRA58_HUMAN
NC score	0.100161 (rank : 31)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	121	Target Neighborhood Hits	324	Shared Neighborhood Hits	36
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

PTMA_MOUSE
NC score	0.097708 (rank : 32)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	121	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

KR511_HUMAN
NC score	0.094522 (rank : 33)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	121	Target Neighborhood Hits	231	Shared Neighborhood Hits	36
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

PHF6_HUMAN
NC score	0.086731 (rank : 34)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF10_HUMAN
NC score	0.084830 (rank : 35)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	121	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

KRA53_HUMAN
NC score	0.084501 (rank : 36)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	121	Target Neighborhood Hits	331	Shared Neighborhood Hits	39
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

RAI1_MOUSE
NC score	0.084479 (rank : 37)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	121	Target Neighborhood Hits	344	Shared Neighborhood Hits	16
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PHF6_MOUSE
NC score	0.084251 (rank : 38)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF10_MOUSE
NC score	0.083252 (rank : 39)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	121	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

KRA24_HUMAN
NC score	0.082295 (rank : 40)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	121	Target Neighborhood Hits	192	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

RAI1_HUMAN
NC score	0.078234 (rank : 41)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	121	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TCF20_HUMAN
NC score	0.077877 (rank : 42)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	121	Target Neighborhood Hits	323	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

DPF1_HUMAN
NC score	0.075289 (rank : 43)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	121	Target Neighborhood Hits	136	Shared Neighborhood Hits	8
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TCF20_MOUSE
NC score	0.074775 (rank : 44)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	121	Target Neighborhood Hits	396	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

KRA57_HUMAN
NC score	0.073172 (rank : 45)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	35
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

SMYD3_HUMAN
NC score	0.070677 (rank : 46)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	121	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

PHF7_HUMAN
NC score	0.070541 (rank : 47)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	121	Target Neighborhood Hits	71	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

SMYD3_MOUSE
NC score	0.070181 (rank : 48)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	121	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

MYST4_HUMAN
NC score	0.068366 (rank : 49)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	121	Target Neighborhood Hits	671	Shared Neighborhood Hits	19
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

DPF1_MOUSE
NC score	0.066502 (rank : 50)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	121	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

KRA59_HUMAN
NC score	0.066334 (rank : 51)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	121	Target Neighborhood Hits	310	Shared Neighborhood Hits	39
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

AIRE_MOUSE
NC score	0.066023 (rank : 52)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

REQU_HUMAN
NC score	0.065921 (rank : 53)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	121	Target Neighborhood Hits	523	Shared Neighborhood Hits	9
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

KRA44_HUMAN
NC score	0.065811 (rank : 54)	θ value	0.279714 (rank : 34)
Query Neighborhood Hits	121	Target Neighborhood Hits	162	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

PHF7_MOUSE
NC score	0.065634 (rank : 55)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	121	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

REQU_MOUSE
NC score	0.065455 (rank : 56)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	121	Target Neighborhood Hits	519	Shared Neighborhood Hits	9
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

K1333_HUMAN
NC score	0.064635 (rank : 57)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	121	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
NC score	0.064619 (rank : 58)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	121	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

LCE1D_HUMAN
NC score	0.063697 (rank : 59)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

AIRE_HUMAN
NC score	0.063694 (rank : 60)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	121	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

KRA45_HUMAN
NC score	0.061230 (rank : 61)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	121	Target Neighborhood Hits	194	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

MYST4_MOUSE
NC score	0.061172 (rank : 62)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	121	Target Neighborhood Hits	416	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

LCE1E_HUMAN
NC score	0.060890 (rank : 63)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	121	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

PF21A_HUMAN
NC score	0.060008 (rank : 64)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	121	Target Neighborhood Hits	303	Shared Neighborhood Hits	11
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

CBX3_MOUSE
NC score	0.059817 (rank : 65)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	121	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

PF21A_MOUSE
NC score	0.059267 (rank : 66)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	121	Target Neighborhood Hits	285	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

CBX3_HUMAN
NC score	0.059231 (rank : 67)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	121	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

MYST3_MOUSE
NC score	0.058437 (rank : 68)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	121	Target Neighborhood Hits	688	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

CBX1_HUMAN
NC score	0.057697 (rank : 69)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.057697 (rank : 70)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

MYST3_HUMAN
NC score	0.056384 (rank : 71)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	121	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

KR105_HUMAN
NC score	0.055841 (rank : 72)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	121	Target Neighborhood Hits	271	Shared Neighborhood Hits	40
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

UHRF1_MOUSE
NC score	0.055055 (rank : 73)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CBX5_HUMAN
NC score	0.054799 (rank : 74)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	121	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

PHF12_MOUSE
NC score	0.054708 (rank : 75)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	121	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PF21B_MOUSE
NC score	0.054688 (rank : 76)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	13
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
NC score	0.054632 (rank : 77)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	121	Target Neighborhood Hits	174	Shared Neighborhood Hits	11
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CBX5_MOUSE
NC score	0.054494 (rank : 78)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	121	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

NCOR2_HUMAN
NC score	0.053900 (rank : 79)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	121	Target Neighborhood Hits	870	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

KRA94_HUMAN
NC score	0.052886 (rank : 80)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	121	Target Neighborhood Hits	204	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

UHRF1_HUMAN
NC score	0.052251 (rank : 81)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	121	Target Neighborhood Hits	272	Shared Neighborhood Hits	10
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ZNFX1_MOUSE
NC score	0.052236 (rank : 82)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	121	Target Neighborhood Hits	407	Shared Neighborhood Hits	39
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

LCE1C_HUMAN
NC score	0.050670 (rank : 83)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	121	Target Neighborhood Hits	65	Shared Neighborhood Hits	18
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

KR103_HUMAN
NC score	0.050630 (rank : 84)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	121	Target Neighborhood Hits	212	Shared Neighborhood Hits	36
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

MDC1_HUMAN
NC score	0.050454 (rank : 85)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	121	Target Neighborhood Hits	1446	Shared Neighborhood Hits	28
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

UHRF2_HUMAN
NC score	0.050180 (rank : 86)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

PF21B_HUMAN
NC score	0.050036 (rank : 87)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	121	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

ZNFX1_HUMAN
NC score	0.049953 (rank : 88)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	121	Target Neighborhood Hits	308	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

KR102_HUMAN
NC score	0.048079 (rank : 89)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	121	Target Neighborhood Hits	264	Shared Neighborhood Hits	36
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KRA93_HUMAN
NC score	0.047527 (rank : 90)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	121	Target Neighborhood Hits	203	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

TNR7_MOUSE
NC score	0.046799 (rank : 91)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	121	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P41272	Gene names	Tnfrsf7, Cd27
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27).

NCOR2_MOUSE
NC score	0.046678 (rank : 92)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	121	Target Neighborhood Hits	790	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NCOR1_HUMAN
NC score	0.046268 (rank : 93)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	121	Target Neighborhood Hits	577	Shared Neighborhood Hits	17
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

ZAN_MOUSE
NC score	0.045559 (rank : 94)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	121	Target Neighborhood Hits	808	Shared Neighborhood Hits	51
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

KRA98_HUMAN
NC score	0.044140 (rank : 95)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	121	Target Neighborhood Hits	185	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NOTC2_HUMAN
NC score	0.042842 (rank : 96)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	121	Target Neighborhood Hits	1113	Shared Neighborhood Hits	56
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR10B_HUMAN
NC score	0.042302 (rank : 97)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	39
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

CRIM1_HUMAN
NC score	0.041878 (rank : 98)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	121	Target Neighborhood Hits	362	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR109_HUMAN
NC score	0.039637 (rank : 99)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	121	Target Neighborhood Hits	226	Shared Neighborhood Hits	34
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

TARA_HUMAN
NC score	0.039512 (rank : 100)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	121	Target Neighborhood Hits	1626	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CCD16_HUMAN
NC score	0.039458 (rank : 101)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	121	Target Neighborhood Hits	190	Shared Neighborhood Hits	5
SwissProt Accessions	Q96NB3, Q96F60, Q96GZ5, Q9BU38	Gene names	CCDC16
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16.

NOTC2_MOUSE
NC score	0.038877 (rank : 102)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	121	Target Neighborhood Hits	1069	Shared Neighborhood Hits	52
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ITB1_HUMAN
NC score	0.038706 (rank : 103)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	121	Target Neighborhood Hits	298	Shared Neighborhood Hits	30
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KR101_HUMAN
NC score	0.038353 (rank : 104)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	121	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

BSN_MOUSE
NC score	0.037786 (rank : 105)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	121	Target Neighborhood Hits	2057	Shared Neighborhood Hits	32
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ITB2_MOUSE
NC score	0.036853 (rank : 106)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	121	Target Neighborhood Hits	326	Shared Neighborhood Hits	29
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

MUC5B_HUMAN
NC score	0.036590 (rank : 107)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	121	Target Neighborhood Hits	1020	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

SEPP1_HUMAN
NC score	0.035366 (rank : 108)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	121	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P49908, Q6PD59, Q6PI43, Q6PI87, Q6PJF9	Gene names	SEPP1, SELP
Domain Architecture
Description	Selenoprotein P precursor (SeP).

VWF_MOUSE
NC score	0.035191 (rank : 109)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	121	Target Neighborhood Hits	381	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NOTC1_HUMAN
NC score	0.034805 (rank : 110)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	121	Target Neighborhood Hits	906	Shared Neighborhood Hits	45
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

MYSM1_HUMAN
NC score	0.032156 (rank : 111)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	121	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

SREC2_HUMAN
NC score	0.031960 (rank : 112)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	121	Target Neighborhood Hits	645	Shared Neighborhood Hits	50
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SSPO_MOUSE
NC score	0.031773 (rank : 113)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	121	Target Neighborhood Hits	800	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

NP1L1_MOUSE
NC score	0.030665 (rank : 114)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	121	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	P28656, Q3UL14	Gene names	Nap1l1, Nrp
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (Brain protein DN38).

NCOR1_MOUSE
NC score	0.030443 (rank : 115)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	121	Target Neighborhood Hits	521	Shared Neighborhood Hits	12
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

ITB2_HUMAN
NC score	0.030174 (rank : 116)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	121	Target Neighborhood Hits	282	Shared Neighborhood Hits	26
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

SREC2_MOUSE
NC score	0.029947 (rank : 117)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	121	Target Neighborhood Hits	605	Shared Neighborhood Hits	52
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

NOTC1_MOUSE
NC score	0.029879 (rank : 118)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	121	Target Neighborhood Hits	916	Shared Neighborhood Hits	44
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CDR1_HUMAN
NC score	0.029367 (rank : 119)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	121	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P51861	Gene names	CDR1
Domain Architecture	No domain graphic available
Description	Cerebellar degeneration-related antigen 1 (CDR34).

VEGFC_MOUSE
NC score	0.028847 (rank : 120)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	121	Target Neighborhood Hits	119	Shared Neighborhood Hits	18
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

TARA_MOUSE
NC score	0.028826 (rank : 121)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	121	Target Neighborhood Hits	1133	Shared Neighborhood Hits	24
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BSN_HUMAN
NC score	0.028359 (rank : 122)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	121	Target Neighborhood Hits	1537	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

PZRN3_MOUSE
NC score	0.026737 (rank : 123)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	121	Target Neighborhood Hits	447	Shared Neighborhood Hits	8
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

STAB2_MOUSE
NC score	0.025837 (rank : 124)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	121	Target Neighborhood Hits	528	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TNR7_HUMAN
NC score	0.025014 (rank : 125)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	121	Target Neighborhood Hits	120	Shared Neighborhood Hits	10
SwissProt Accessions	P26842	Gene names	TNFRSF7, CD27
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 7 precursor (CD27L receptor) (T-cell activation antigen CD27) (T14).

CCD16_MOUSE
NC score	0.023255 (rank : 126)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	121	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R1N0, Q3TR52, Q9CWV9, Q9CYI6	Gene names	Ccdc16, Omcg1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 16 (Ovus mutant candidate gene 1 protein).

MEGF6_HUMAN
NC score	0.022939 (rank : 127)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	121	Target Neighborhood Hits	671	Shared Neighborhood Hits	48
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

PZRN3_HUMAN
NC score	0.022621 (rank : 128)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	121	Target Neighborhood Hits	461	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

STAB2_HUMAN
NC score	0.022195 (rank : 129)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	121	Target Neighborhood Hits	534	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CFDP1_HUMAN
NC score	0.021982 (rank : 130)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	121	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UEE9, O00393, O00404, Q9UEF0, Q9UEF1, Q9UEF8	Gene names	CFDP1, BCNT
Domain Architecture	No domain graphic available
Description	Craniofacial development protein 1 (Bucentaur).

ACY3_HUMAN
NC score	0.021242 (rank : 131)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	121	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HD9	Gene names	ACY3, ASPA2
Domain Architecture
Description	Aspartoacylase-2 (EC 3.5.1.15) (Aminoacylase-3) (ACY-3) (Acylase III) (Hepatitis C virus core-binding protein 1) (HCBP1).

TRI42_HUMAN
NC score	0.018760 (rank : 132)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	121	Target Neighborhood Hits	283	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

SPY2_MOUSE
NC score	0.017747 (rank : 133)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	121	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QXV8, Q9WUQ9	Gene names	Spry2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

KIF4A_HUMAN
NC score	0.017720 (rank : 134)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	121	Target Neighborhood Hits	1159	Shared Neighborhood Hits	26
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

NP1L1_HUMAN
NC score	0.017137 (rank : 135)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	121	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	P55209	Gene names	NAP1L1, NRP
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP).

SPY2_HUMAN
NC score	0.016673 (rank : 136)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	121	Target Neighborhood Hits	66	Shared Neighborhood Hits	16
SwissProt Accessions	O43597, Q5T6Z7	Gene names	SPRY2
Domain Architecture
Description	Sprouty homolog 2 (Spry-2).

AFF1_MOUSE
NC score	0.016191 (rank : 137)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	121	Target Neighborhood Hits	351	Shared Neighborhood Hits	9
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

NRDC_MOUSE
NC score	0.015735 (rank : 138)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	121	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHG1	Gene names	Nrd1
Domain Architecture
Description	Nardilysin precursor (EC 3.4.24.61) (N-arginine dibasic convertase) (NRD convertase) (NRD-C).

TECT2_MOUSE
NC score	0.014465 (rank : 139)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	121	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q2MV57, Q6PDZ5, Q8C0B3, Q9CXF5	Gene names	Tect2
Domain Architecture	No domain graphic available
Description	Tectonic-2 precursor.

RYR1_HUMAN
NC score	0.012783 (rank : 140)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	121	Target Neighborhood Hits	303	Shared Neighborhood Hits	6
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

HTRA3_HUMAN
NC score	0.012086 (rank : 141)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	121	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	P83110, Q7Z7A2	Gene names	HTRA3, PRSP
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).

HTRA3_MOUSE
NC score	0.011623 (rank : 142)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	121	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D236, Q6WLC5, Q6YDR0	Gene names	Htra3, Prsp, Tasp
Domain Architecture
Description	Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).

AP3B2_MOUSE
NC score	0.010531 (rank : 143)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	121	Target Neighborhood Hits	246	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

KIF4A_MOUSE
NC score	0.010362 (rank : 144)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	121	Target Neighborhood Hits	1033	Shared Neighborhood Hits	22
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

CYLC1_HUMAN
NC score	0.010102 (rank : 145)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	121	Target Neighborhood Hits	408	Shared Neighborhood Hits	7
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

CC019_HUMAN
NC score	0.008757 (rank : 146)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	121	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PII3, Q96CS5	Gene names	C3orf19
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf19.

TAIP2_MOUSE
NC score	0.008069 (rank : 147)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	4
SwissProt Accessions	P59055	Gene names	Taip2
Domain Architecture	No domain graphic available
Description	TGF-beta-induced apoptosis protein 2 (TAIP-2).

TAF5_HUMAN
NC score	0.007854 (rank : 148)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	121	Target Neighborhood Hits	352	Shared Neighborhood Hits	5
SwissProt Accessions	Q15542, Q86UZ7, Q9Y4K5	Gene names	TAF5, TAF2D
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

TAF5_MOUSE
NC score	0.006624 (rank : 149)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	121	Target Neighborhood Hits	366	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C092, Q8BTR2	Gene names	Taf5
Domain Architecture
Description	Transcription initiation factor TFIID subunit 5 (Transcription initiation factor TFIID 100 kDa subunit) (TAF(II)100) (TAFII-100) (TAFII100).

SMCA2_HUMAN
NC score	0.006496 (rank : 150)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	121	Target Neighborhood Hits	503	Shared Neighborhood Hits	12
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

WNT1_MOUSE
NC score	0.004921 (rank : 151)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P04426	Gene names	Wnt1, Int-1, Wnt-1
Domain Architecture
Description	Proto-oncogene protein Wnt-1 precursor.

WNT1_HUMAN
NC score	0.004920 (rank : 152)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	P04628	Gene names	WNT1, INT1
Domain Architecture
Description	Proto-oncogene protein Wnt-1 precursor.

NUCL_HUMAN
NC score	0.004667 (rank : 153)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	121	Target Neighborhood Hits	415	Shared Neighborhood Hits	6
SwissProt Accessions	P19338, Q53SK1, Q8NB06	Gene names	NCL
Domain Architecture
Description	Nucleolin (Protein C23).

CSTN2_MOUSE
NC score	0.004211 (rank : 154)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	121	Target Neighborhood Hits	149	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ER65	Gene names	Clstn2, Cs2, Cstn2
Domain Architecture
Description	Calsyntenin-2 precursor.

SCN2A_HUMAN
NC score	0.004077 (rank : 155)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	121	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

CE152_HUMAN
NC score	0.004018 (rank : 156)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	121	Target Neighborhood Hits	976	Shared Neighborhood Hits	11
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

LUM_HUMAN
NC score	0.002493 (rank : 157)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	121	Target Neighborhood Hits	284	Shared Neighborhood Hits	3
SwissProt Accessions	P51884, Q96QM7	Gene names	LUM, LDC
Domain Architecture
Description	Lumican precursor (Keratan sulfate proteoglycan lumican) (KSPG lumican).

CS1A_MOUSE
NC score	0.001669 (rank : 158)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	121	Target Neighborhood Hits	360	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

TRIO_HUMAN
NC score	0.001533 (rank : 159)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	121	Target Neighborhood Hits	1580	Shared Neighborhood Hits	14
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

ROCK2_HUMAN
NC score	0.000313 (rank : 160)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	121	Target Neighborhood Hits	2073	Shared Neighborhood Hits	19
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
NC score	-0.001705 (rank : 161)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	121	Target Neighborhood Hits	2072	Shared Neighborhood Hits	16
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ZNF31_HUMAN
NC score	-0.003063 (rank : 162)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	121	Target Neighborhood Hits	769	Shared Neighborhood Hits	3
SwissProt Accessions	P17040, Q96H84	Gene names	ZNF31, KOX29, ZNF360, ZSCAN20
Domain Architecture	No domain graphic available
Description	Zinc finger protein 31 (Zinc finger protein KOX29) (Zinc finger and SCAN domain-containing protein 20) (Zinc finger protein 360).