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Network neighborhood for query Sequence : SETD8_MOUSE

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SETD8_MOUSE
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SETD8_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
θ value	3.47146e-177 (rank : 2)	NC score	0.970602 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

HRX_HUMAN
θ value	5.8054e-15 (rank : 3)	NC score	0.536192 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	825	Shared Neighborhood Hits	59
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
θ value	2.0648e-12 (rank : 4)	NC score	0.503750 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	722	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SUV91_HUMAN
θ value	3.89403e-11 (rank : 5)	NC score	0.614246 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	6.64225e-11 (rank : 6)	NC score	0.607780 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

EZH1_HUMAN
θ value	1.47974e-10 (rank : 7)	NC score	0.610503 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	1.47974e-10 (rank : 8)	NC score	0.611616 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

MLL2_HUMAN
θ value	1.47974e-10 (rank : 9)	NC score	0.385357 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	1788	Shared Neighborhood Hits	59
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

EZH2_HUMAN
θ value	3.29651e-10 (rank : 10)	NC score	0.611189 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SUV92_HUMAN
θ value	9.59137e-10 (rank : 11)	NC score	0.607620 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EZH2_MOUSE
θ value	1.63604e-09 (rank : 12)	NC score	0.606141 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SETD2_HUMAN
θ value	1.63604e-09 (rank : 13)	NC score	0.562840 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	412	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EHMT2_HUMAN
θ value	2.79066e-09 (rank : 14)	NC score	0.296885 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	2.79066e-09 (rank : 15)	NC score	0.296747 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	750	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

SUV92_MOUSE
θ value	3.64472e-09 (rank : 16)	NC score	0.598405 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

MLL3_HUMAN
θ value	2.36244e-08 (rank : 17)	NC score	0.373999 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	1644	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	5.26297e-08 (rank : 18)	NC score	0.392116 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	1399	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SET1A_HUMAN
θ value	4.45536e-07 (rank : 19)	NC score	0.513332 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	690	Shared Neighborhood Hits	46
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

NSD1_HUMAN
θ value	1.29631e-06 (rank : 20)	NC score	0.464075 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	427	Shared Neighborhood Hits	47
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	1.29631e-06 (rank : 21)	NC score	0.466594 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	472	Shared Neighborhood Hits	54
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

EHMT1_HUMAN
θ value	1.69304e-06 (rank : 22)	NC score	0.281491 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

TRDN_HUMAN
θ value	0.00102713 (rank : 23)	NC score	0.119071 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	542	Shared Neighborhood Hits	31
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ADDB_MOUSE
θ value	0.00390308 (rank : 24)	NC score	0.094480 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	574	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

BRE1B_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.052672 (rank : 141)
Query Neighborhood Hits	131	Target Neighborhood Hits	970	Shared Neighborhood Hits	21
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

ABCF1_HUMAN
θ value	0.0330416 (rank : 26)	NC score	0.047630 (rank : 157)
Query Neighborhood Hits	131	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

BRD3_HUMAN
θ value	0.0330416 (rank : 27)	NC score	0.080096 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	369	Shared Neighborhood Hits	23
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

NFH_HUMAN
θ value	0.0330416 (rank : 28)	NC score	0.046549 (rank : 160)
Query Neighborhood Hits	131	Target Neighborhood Hits	1242	Shared Neighborhood Hits	55
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

LAD1_HUMAN
θ value	0.0736092 (rank : 29)	NC score	0.129259 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	441	Shared Neighborhood Hits	41
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PRP4B_MOUSE
θ value	0.0736092 (rank : 30)	NC score	0.023905 (rank : 195)
Query Neighborhood Hits	131	Target Neighborhood Hits	1040	Shared Neighborhood Hits	29
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

SFR11_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.097694 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

TITIN_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.022610 (rank : 196)
Query Neighborhood Hits	131	Target Neighborhood Hits	2923	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

JHD1B_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.083758 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

AFF1_HUMAN
θ value	0.21417 (rank : 34)	NC score	0.061126 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	37
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

BRE1B_HUMAN
θ value	0.21417 (rank : 35)	NC score	0.049657 (rank : 153)
Query Neighborhood Hits	131	Target Neighborhood Hits	1040	Shared Neighborhood Hits	32
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

INCE_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.035560 (rank : 173)
Query Neighborhood Hits	131	Target Neighborhood Hits	978	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

RIMS1_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.034430 (rank : 176)
Query Neighborhood Hits	131	Target Neighborhood Hits	437	Shared Neighborhood Hits	20
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

BRD4_HUMAN
θ value	0.279714 (rank : 38)	NC score	0.090067 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	851	Shared Neighborhood Hits	37
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

ENL_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.058916 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

SMYD3_HUMAN
θ value	0.365318 (rank : 40)	NC score	0.113583 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
θ value	0.365318 (rank : 41)	NC score	0.113153 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

XYLT1_MOUSE
θ value	0.365318 (rank : 42)	NC score	0.046979 (rank : 158)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

CCD96_HUMAN
θ value	0.47712 (rank : 43)	NC score	0.039103 (rank : 170)
Query Neighborhood Hits	131	Target Neighborhood Hits	595	Shared Neighborhood Hits	20
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

HUCE1_HUMAN
θ value	0.47712 (rank : 44)	NC score	0.059656 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O43159, Q7KZ78, Q9BVM6	Gene names	KIAA0409
Domain Architecture	No domain graphic available
Description	Cerebral protein 1.

LYRIC_MOUSE
θ value	0.47712 (rank : 45)	NC score	0.092372 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

BRD4_MOUSE
θ value	0.62314 (rank : 46)	NC score	0.079304 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	845	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

FA44A_HUMAN
θ value	0.62314 (rank : 47)	NC score	0.054489 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	280	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

SETB2_HUMAN
θ value	0.62314 (rank : 48)	NC score	0.373404 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

CING_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.021032 (rank : 198)
Query Neighborhood Hits	131	Target Neighborhood Hits	1432	Shared Neighborhood Hits	42
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

RBMX2_MOUSE
θ value	0.813845 (rank : 50)	NC score	0.020833 (rank : 200)
Query Neighborhood Hits	131	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

ANR38_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.041362 (rank : 168)
Query Neighborhood Hits	131	Target Neighborhood Hits	512	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

BRCA2_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.033093 (rank : 179)
Query Neighborhood Hits	131	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

CNGA1_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.020239 (rank : 202)
Query Neighborhood Hits	131	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

DDIT3_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.052580 (rank : 145)
Query Neighborhood Hits	131	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

DDX46_HUMAN
θ value	1.38821 (rank : 55)	NC score	0.012409 (rank : 213)
Query Neighborhood Hits	131	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

MARK2_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.007588 (rank : 223)
Query Neighborhood Hits	131	Target Neighborhood Hits	1018	Shared Neighborhood Hits	24
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

SALL2_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.003809 (rank : 227)
Query Neighborhood Hits	131	Target Neighborhood Hits	836	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

SYNJ1_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.043989 (rank : 164)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	25
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TXND2_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.080129 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	63
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

AP3D1_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.025290 (rank : 194)
Query Neighborhood Hits	131	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

BRD3_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.074884 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	402	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CNGA1_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.026586 (rank : 191)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

DDIT3_MOUSE
θ value	1.81305 (rank : 63)	NC score	0.049475 (rank : 155)
Query Neighborhood Hits	131	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P35639, Q91YW9	Gene names	Ddit3, Chop, Gadd153
Domain Architecture	No domain graphic available
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

HCLS1_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.032183 (rank : 181)
Query Neighborhood Hits	131	Target Neighborhood Hits	358	Shared Neighborhood Hits	19
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

JHD1B_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.077651 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	214	Shared Neighborhood Hits	21
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

LYRIC_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.074277 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	99	Shared Neighborhood Hits	17
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

NOLC1_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.058133 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CT174_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.048482 (rank : 156)
Query Neighborhood Hits	131	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

K0690_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.034102 (rank : 177)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

MOR2A_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.026811 (rank : 190)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

SRRM2_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.075501 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

AFF4_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.056890 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	611	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

M4K2_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.003390 (rank : 228)
Query Neighborhood Hits	131	Target Neighborhood Hits	850	Shared Neighborhood Hits	9
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).

MARK2_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.007266 (rank : 224)
Query Neighborhood Hits	131	Target Neighborhood Hits	1056	Shared Neighborhood Hits	28
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MK07_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.010183 (rank : 216)
Query Neighborhood Hits	131	Target Neighborhood Hits	1087	Shared Neighborhood Hits	23
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

MK07_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.011674 (rank : 214)
Query Neighborhood Hits	131	Target Neighborhood Hits	1054	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

SNIP_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.042977 (rank : 167)
Query Neighborhood Hits	131	Target Neighborhood Hits	313	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

CBP_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.049578 (rank : 154)
Query Neighborhood Hits	131	Target Neighborhood Hits	1051	Shared Neighborhood Hits	37
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CKAP5_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.033404 (rank : 178)
Query Neighborhood Hits	131	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

CYLC2_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.043799 (rank : 166)
Query Neighborhood Hits	131	Target Neighborhood Hits	223	Shared Neighborhood Hits	17
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

ERRFI_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.026567 (rank : 192)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

IF2P_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.028735 (rank : 187)
Query Neighborhood Hits	131	Target Neighborhood Hits	889	Shared Neighborhood Hits	29
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LSR_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.020860 (rank : 199)
Query Neighborhood Hits	131	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

MAGI2_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.010612 (rank : 215)
Query Neighborhood Hits	131	Target Neighborhood Hits	373	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

RIMS2_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.026003 (rank : 193)
Query Neighborhood Hits	131	Target Neighborhood Hits	342	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

TACC2_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.030348 (rank : 184)
Query Neighborhood Hits	131	Target Neighborhood Hits	856	Shared Neighborhood Hits	41
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ZCPW1_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.078310 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

BRDT_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.053718 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	243	Shared Neighborhood Hits	20
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CAF1A_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.029550 (rank : 186)
Query Neighborhood Hits	131	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CEBPD_MOUSE
θ value	5.27518 (rank : 90)	NC score	0.018375 (rank : 207)
Query Neighborhood Hits	131	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

CHD3_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.046665 (rank : 159)
Query Neighborhood Hits	131	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD6_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.018508 (rank : 206)
Query Neighborhood Hits	131	Target Neighborhood Hits	342	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

K0690_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.030607 (rank : 183)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTH9, Q5JTH8, Q69YK4, Q96E87, Q9BUH3, Q9Y4C7	Gene names	KIAA0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

LACTB_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.021078 (rank : 197)
Query Neighborhood Hits	131	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

MAP2_MOUSE
θ value	5.27518 (rank : 95)	NC score	0.040843 (rank : 169)
Query Neighborhood Hits	131	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MINT_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.053172 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	1291	Shared Neighborhood Hits	57
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_MOUSE
θ value	5.27518 (rank : 97)	NC score	0.071007 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	2247	Shared Neighborhood Hits	88
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PCLO_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.064581 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	2046	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRG4_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.043961 (rank : 165)
Query Neighborhood Hits	131	Target Neighborhood Hits	764	Shared Neighborhood Hits	35
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TTF1_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.034853 (rank : 175)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	30
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

ANK2_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.060024 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	1615	Shared Neighborhood Hits	73
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR12_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.036764 (rank : 171)
Query Neighborhood Hits	131	Target Neighborhood Hits	1081	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CS016_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.045575 (rank : 162)
Query Neighborhood Hits	131	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

H14_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.035219 (rank : 174)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

HMMR_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.017623 (rank : 208)
Query Neighborhood Hits	131	Target Neighborhood Hits	1178	Shared Neighborhood Hits	35
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

MAP1B_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.055219 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	903	Shared Neighborhood Hits	53
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYT1L_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.008023 (rank : 221)
Query Neighborhood Hits	131	Target Neighborhood Hits	471	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

PRP4B_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.014538 (rank : 212)
Query Neighborhood Hits	131	Target Neighborhood Hits	1030	Shared Neighborhood Hits	27
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

RBM28_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.015958 (rank : 211)
Query Neighborhood Hits	131	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

SCYB9_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.028170 (rank : 188)
Query Neighborhood Hits	131	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q07325, Q503B4	Gene names	CXCL9, MIG, SCYB9
Domain Architecture
Description	Small inducible cytokine B9 precursor (CXCL9) (Gamma interferon- induced monokine) (MIG).

SEC62_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.020590 (rank : 201)
Query Neighborhood Hits	131	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

SMRC2_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.030620 (rank : 182)
Query Neighborhood Hits	131	Target Neighborhood Hits	499	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

SMYD1_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.045137 (rank : 163)
Query Neighborhood Hits	131	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

TAF3_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.052659 (rank : 142)
Query Neighborhood Hits	131	Target Neighborhood Hits	568	Shared Neighborhood Hits	38
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TTC16_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.045936 (rank : 161)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ATBF1_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.008646 (rank : 220)
Query Neighborhood Hits	131	Target Neighborhood Hits	1841	Shared Neighborhood Hits	35
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DDX46_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.009151 (rank : 217)
Query Neighborhood Hits	131	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

FOG1_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.007006 (rank : 226)
Query Neighborhood Hits	131	Target Neighborhood Hits	981	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

HMGN3_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.018810 (rank : 205)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCB1, Q7M737, Q99JU1	Gene names	Hmgn3
Domain Architecture	No domain graphic available
Description	High mobility group nucleosome-binding domain-containing protein 3.

K0831_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.016093 (rank : 210)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MINK1_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.008928 (rank : 219)
Query Neighborhood Hits	131	Target Neighborhood Hits	1477	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	8.99809 (rank : 122)	NC score	0.007780 (rank : 222)
Query Neighborhood Hits	131	Target Neighborhood Hits	1451	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYH11_HUMAN
θ value	8.99809 (rank : 123)	NC score	0.009137 (rank : 218)
Query Neighborhood Hits	131	Target Neighborhood Hits	1806	Shared Neighborhood Hits	46
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RENT2_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.016683 (rank : 209)
Query Neighborhood Hits	131	Target Neighborhood Hits	618	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SMYD4_HUMAN
θ value	8.99809 (rank : 125)	NC score	0.027903 (rank : 189)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

STIP1_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.007024 (rank : 225)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

TARA_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.036248 (rank : 172)
Query Neighborhood Hits	131	Target Neighborhood Hits	1133	Shared Neighborhood Hits	48
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

THOC2_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.032786 (rank : 180)
Query Neighborhood Hits	131	Target Neighborhood Hits	337	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

TTC16_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.019536 (rank : 203)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ZC313_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.030343 (rank : 185)
Query Neighborhood Hits	131	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ZN638_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.019528 (rank : 204)
Query Neighborhood Hits	131	Target Neighborhood Hits	318	Shared Neighborhood Hits	20
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

ACINU_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.053917 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

AFF4_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.055332 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	581	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AIRE_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.059699 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.064724 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.062295 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	693	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.070689 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	701	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.062304 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.055616 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	780	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.053292 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	744	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.054663 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	803	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.072832 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	786	Shared Neighborhood Hits	43
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD8_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.050966 (rank : 150)
Query Neighborhood Hits	131	Target Neighborhood Hits	422	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CBX1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.060531 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.060531 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.061571 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.062153 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.058774 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.058008 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CJ012_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.074388 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	467	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CXCC1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.053791 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	143	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.053229 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

DNMT1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.053569 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	401	Shared Neighborhood Hits	37
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

DPF1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.076209 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.068420 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

ELOA1_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.071385 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	388	Shared Neighborhood Hits	49
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

FA47A_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.053566 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	451	Shared Neighborhood Hits	33
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

IWS1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.071810 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	1241	Shared Neighborhood Hits	68
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.078715 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	1258	Shared Neighborhood Hits	67
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

JADE2_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.052791 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	560	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K1333_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.070911 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.071197 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1802_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.051672 (rank : 148)
Query Neighborhood Hits	131	Target Neighborhood Hits	1596	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

KI67_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.057903 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	581	Shared Neighborhood Hits	44
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LAD1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.078786 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	391	Shared Neighborhood Hits	43
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

LCP2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.053885 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	531	Shared Neighborhood Hits	31
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

MAP1A_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.052063 (rank : 146)
Query Neighborhood Hits	131	Target Neighborhood Hits	1626	Shared Neighborhood Hits	72
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MAP1B_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.050722 (rank : 151)
Query Neighborhood Hits	131	Target Neighborhood Hits	977	Shared Neighborhood Hits	52
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MBB1A_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.053706 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	665	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MBD1_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.059184 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

MBD1_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.050306 (rank : 152)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

MDC1_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.088152 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	1446	Shared Neighborhood Hits	69
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.076497 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	998	Shared Neighborhood Hits	55
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MINT_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.053773 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	1514	Shared Neighborhood Hits	69
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MPP8_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.071409 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	948	Shared Neighborhood Hits	58
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYST3_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.066557 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	772	Shared Neighborhood Hits	36
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.065158 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	688	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.070340 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	671	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.063687 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	416	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NACAM_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.071357 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	1866	Shared Neighborhood Hits	67
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NASP_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.053373 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	709	Shared Neighborhood Hits	52
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

NIPBL_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.075302 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	1311	Shared Neighborhood Hits	80
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.075374 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PCLO_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.053287 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	2275	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.061601 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.060136 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.051731 (rank : 147)
Query Neighborhood Hits	131	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.056679 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	278	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.090047 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.088197 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.125885 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF12_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.052884 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.051031 (rank : 149)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.064233 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	394	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF20_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.078823 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	513	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF6_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.095623 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.092917 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.071093 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.066934 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PKCB1_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.071510 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	488	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PRRT3_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.052928 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	998	Shared Neighborhood Hits	40
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RAI1_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.092210 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	360	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.095006 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	25
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RBBP6_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.061290 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.063248 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	1014	Shared Neighborhood Hits	61
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

REQU_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.068373 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	523	Shared Neighborhood Hits	13
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.067330 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	519	Shared Neighborhood Hits	11
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.066544 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	539	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SELPL_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.056621 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	588	Shared Neighborhood Hits	39
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SETB1_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.310906 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.313260 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	150	Shared Neighborhood Hits	26
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETD7_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.074940 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

SETD7_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.074746 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SFRIP_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.052609 (rank : 144)
Query Neighborhood Hits	131	Target Neighborhood Hits	530	Shared Neighborhood Hits	51
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SRRM1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.056262 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	690	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.071624 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	966	Shared Neighborhood Hits	57
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM2_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.064329 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TAF3_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.056754 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	463	Shared Neighborhood Hits	31
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TARA_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.054859 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	1626	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARSH_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.053844 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	768	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TCF20_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.096809 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.087225 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	396	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TGON2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.080266 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	1037	Shared Neighborhood Hits	65
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.097490 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	793	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

UHRF1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.054371 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	272	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.059297 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.055871 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.052639 (rank : 143)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

Hits sorted by NC score

SETD8_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	131
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
NC score	0.970602 (rank : 2)	θ value	3.47146e-177 (rank : 2)
Query Neighborhood Hits	131	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SUV91_HUMAN
NC score	0.614246 (rank : 3)	θ value	3.89403e-11 (rank : 5)
Query Neighborhood Hits	131	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

EZH1_MOUSE
NC score	0.611616 (rank : 4)	θ value	1.47974e-10 (rank : 8)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
NC score	0.611189 (rank : 5)	θ value	3.29651e-10 (rank : 10)
Query Neighborhood Hits	131	Target Neighborhood Hits	84	Shared Neighborhood Hits	24
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_HUMAN
NC score	0.610503 (rank : 6)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	131	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

SUV91_MOUSE
NC score	0.607780 (rank : 7)	θ value	6.64225e-11 (rank : 6)
Query Neighborhood Hits	131	Target Neighborhood Hits	69	Shared Neighborhood Hits	26
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.607620 (rank : 8)	θ value	9.59137e-10 (rank : 11)
Query Neighborhood Hits	131	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

EZH2_MOUSE
NC score	0.606141 (rank : 9)	θ value	1.63604e-09 (rank : 12)
Query Neighborhood Hits	131	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SUV92_MOUSE
NC score	0.598405 (rank : 10)	θ value	3.64472e-09 (rank : 16)
Query Neighborhood Hits	131	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SETD2_HUMAN
NC score	0.562840 (rank : 11)	θ value	1.63604e-09 (rank : 13)
Query Neighborhood Hits	131	Target Neighborhood Hits	412	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HRX_HUMAN
NC score	0.536192 (rank : 12)	θ value	5.8054e-15 (rank : 3)
Query Neighborhood Hits	131	Target Neighborhood Hits	825	Shared Neighborhood Hits	59
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SET1A_HUMAN
NC score	0.513332 (rank : 13)	θ value	4.45536e-07 (rank : 19)
Query Neighborhood Hits	131	Target Neighborhood Hits	690	Shared Neighborhood Hits	46
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

MLL4_HUMAN
NC score	0.503750 (rank : 14)	θ value	2.0648e-12 (rank : 4)
Query Neighborhood Hits	131	Target Neighborhood Hits	722	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NSD1_MOUSE
NC score	0.466594 (rank : 15)	θ value	1.29631e-06 (rank : 21)
Query Neighborhood Hits	131	Target Neighborhood Hits	472	Shared Neighborhood Hits	54
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.464075 (rank : 16)	θ value	1.29631e-06 (rank : 20)
Query Neighborhood Hits	131	Target Neighborhood Hits	427	Shared Neighborhood Hits	47
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MLL3_MOUSE
NC score	0.392116 (rank : 17)	θ value	5.26297e-08 (rank : 18)
Query Neighborhood Hits	131	Target Neighborhood Hits	1399	Shared Neighborhood Hits	69
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.385357 (rank : 18)	θ value	1.47974e-10 (rank : 9)
Query Neighborhood Hits	131	Target Neighborhood Hits	1788	Shared Neighborhood Hits	59
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.373999 (rank : 19)	θ value	2.36244e-08 (rank : 17)
Query Neighborhood Hits	131	Target Neighborhood Hits	1644	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SETB2_HUMAN
NC score	0.373404 (rank : 20)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	131	Target Neighborhood Hits	62	Shared Neighborhood Hits	23
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.313260 (rank : 21)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	131	Target Neighborhood Hits	150	Shared Neighborhood Hits	26
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.310906 (rank : 22)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	131	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

EHMT2_HUMAN
NC score	0.296885 (rank : 23)	θ value	2.79066e-09 (rank : 14)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.296747 (rank : 24)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	131	Target Neighborhood Hits	750	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.281491 (rank : 25)	θ value	1.69304e-06 (rank : 22)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

LAD1_HUMAN
NC score	0.129259 (rank : 26)	θ value	0.0736092 (rank : 29)
Query Neighborhood Hits	131	Target Neighborhood Hits	441	Shared Neighborhood Hits	41
SwissProt Accessions	O00515, O95614	Gene names	LAD1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (120 kDa linear IgA bullous dermatosis antigen) (97 kDa linear IgA bullous dermatosis antigen) (Linear IgA disease antigen homolog) (LadA).

PHF11_HUMAN
NC score	0.125885 (rank : 27)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	131	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

TRDN_HUMAN
NC score	0.119071 (rank : 28)	θ value	0.00102713 (rank : 23)
Query Neighborhood Hits	131	Target Neighborhood Hits	542	Shared Neighborhood Hits	31
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

SMYD3_HUMAN
NC score	0.113583 (rank : 29)	θ value	0.365318 (rank : 40)
Query Neighborhood Hits	131	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
NC score	0.113153 (rank : 30)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	131	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SFR11_HUMAN
NC score	0.097694 (rank : 31)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	131	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

TXND2_HUMAN
NC score	0.097490 (rank : 32)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	131	Target Neighborhood Hits	793	Shared Neighborhood Hits	60
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TCF20_HUMAN
NC score	0.096809 (rank : 33)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	131	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PHF6_HUMAN
NC score	0.095623 (rank : 34)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

RAI1_MOUSE
NC score	0.095006 (rank : 35)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	131	Target Neighborhood Hits	344	Shared Neighborhood Hits	25
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

ADDB_MOUSE
NC score	0.094480 (rank : 36)	θ value	0.00390308 (rank : 24)
Query Neighborhood Hits	131	Target Neighborhood Hits	574	Shared Neighborhood Hits	53
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

PHF6_MOUSE
NC score	0.092917 (rank : 37)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

LYRIC_MOUSE
NC score	0.092372 (rank : 38)	θ value	0.47712 (rank : 45)
Query Neighborhood Hits	131	Target Neighborhood Hits	126	Shared Neighborhood Hits	18
SwissProt Accessions	Q80WJ7, Q3U9F8, Q3UAQ8, Q8BN67, Q8CBT9, Q8CDL0, Q8CGI7, Q9D052	Gene names	Mtdh, Lyric
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/LYRIC) (Metastasis adhesion protein) (Metadherin).

RAI1_HUMAN
NC score	0.092210 (rank : 39)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	131	Target Neighborhood Hits	360	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

BRD4_HUMAN
NC score	0.090067 (rank : 40)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	131	Target Neighborhood Hits	851	Shared Neighborhood Hits	37
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

PHF10_HUMAN
NC score	0.090047 (rank : 41)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	131	Target Neighborhood Hits	151	Shared Neighborhood Hits	16
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.088197 (rank : 42)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	131	Target Neighborhood Hits	131	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

MDC1_HUMAN
NC score	0.088152 (rank : 43)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	131	Target Neighborhood Hits	1446	Shared Neighborhood Hits	69
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

TCF20_MOUSE
NC score	0.087225 (rank : 44)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	131	Target Neighborhood Hits	396	Shared Neighborhood Hits	24
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

JHD1B_HUMAN
NC score	0.083758 (rank : 45)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	131	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

TGON2_HUMAN
NC score	0.080266 (rank : 46)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	131	Target Neighborhood Hits	1037	Shared Neighborhood Hits	65
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TXND2_MOUSE
NC score	0.080129 (rank : 47)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	63
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

BRD3_HUMAN
NC score	0.080096 (rank : 48)	θ value	0.0330416 (rank : 27)
Query Neighborhood Hits	131	Target Neighborhood Hits	369	Shared Neighborhood Hits	23
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD4_MOUSE
NC score	0.079304 (rank : 49)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	131	Target Neighborhood Hits	845	Shared Neighborhood Hits	34
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

PHF20_MOUSE
NC score	0.078823 (rank : 50)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	131	Target Neighborhood Hits	513	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

LAD1_MOUSE
NC score	0.078786 (rank : 51)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	131	Target Neighborhood Hits	391	Shared Neighborhood Hits	43
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

IWS1_MOUSE
NC score	0.078715 (rank : 52)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	131	Target Neighborhood Hits	1258	Shared Neighborhood Hits	67
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZCPW1_MOUSE
NC score	0.078310 (rank : 53)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	131	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

JHD1B_MOUSE
NC score	0.077651 (rank : 54)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	131	Target Neighborhood Hits	214	Shared Neighborhood Hits	21
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MDC1_MOUSE
NC score	0.076497 (rank : 55)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	131	Target Neighborhood Hits	998	Shared Neighborhood Hits	55
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

DPF1_HUMAN
NC score	0.076209 (rank : 56)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	131	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

SRRM2_HUMAN
NC score	0.075501 (rank : 57)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	131	Target Neighborhood Hits	1296	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NPBL_MOUSE
NC score	0.075374 (rank : 58)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	131	Target Neighborhood Hits	1041	Shared Neighborhood Hits	74
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NIPBL_HUMAN
NC score	0.075302 (rank : 59)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	131	Target Neighborhood Hits	1311	Shared Neighborhood Hits	80
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SETD7_HUMAN
NC score	0.074940 (rank : 60)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

BRD3_MOUSE
NC score	0.074884 (rank : 61)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	131	Target Neighborhood Hits	402	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

SETD7_MOUSE
NC score	0.074746 (rank : 62)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

CJ012_HUMAN
NC score	0.074388 (rank : 63)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	131	Target Neighborhood Hits	467	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

LYRIC_HUMAN
NC score	0.074277 (rank : 64)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	131	Target Neighborhood Hits	99	Shared Neighborhood Hits	17
SwissProt Accessions	Q86UE4, Q6PK07, Q8TCX3	Gene names	MTDH, AEG1, LYRIC
Domain Architecture	No domain graphic available
Description	Protein LYRIC (Lysine-rich CEACAM1 co-isolated protein) (3D3/lyric) (Metastasis adhesion protein) (Metadherin) (Astrocyte elevated gene-1 protein) (AEG-1).

BPTF_HUMAN
NC score	0.072832 (rank : 65)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	131	Target Neighborhood Hits	786	Shared Neighborhood Hits	43
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

IWS1_HUMAN
NC score	0.071810 (rank : 66)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	131	Target Neighborhood Hits	1241	Shared Neighborhood Hits	68
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SRRM1_MOUSE
NC score	0.071624 (rank : 67)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	131	Target Neighborhood Hits	966	Shared Neighborhood Hits	57
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

PKCB1_HUMAN
NC score	0.071510 (rank : 68)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	131	Target Neighborhood Hits	488	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

MPP8_HUMAN
NC score	0.071409 (rank : 69)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	131	Target Neighborhood Hits	948	Shared Neighborhood Hits	58
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

ELOA1_HUMAN
NC score	0.071385 (rank : 70)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	131	Target Neighborhood Hits	388	Shared Neighborhood Hits	49
SwissProt Accessions	Q14241, Q8IXH1	Gene names	TCEB3
Domain Architecture
Description	Transcription elongation factor B polypeptide 3 (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Elongin-A) (EloA) (Elongin 110 kDa subunit).

NACAM_MOUSE
NC score	0.071357 (rank : 71)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	131	Target Neighborhood Hits	1866	Shared Neighborhood Hits	67
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

K1333_MOUSE
NC score	0.071197 (rank : 72)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	131	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PHF7_HUMAN
NC score	0.071093 (rank : 73)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	131	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

NFH_MOUSE
NC score	0.071007 (rank : 74)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	131	Target Neighborhood Hits	2247	Shared Neighborhood Hits	88
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

K1333_HUMAN
NC score	0.070911 (rank : 75)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	131	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

BAZ1B_HUMAN
NC score	0.070689 (rank : 76)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	131	Target Neighborhood Hits	701	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

MYST4_HUMAN
NC score	0.070340 (rank : 77)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	131	Target Neighborhood Hits	671	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

DPF1_MOUSE
NC score	0.068420 (rank : 78)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	131	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.068373 (rank : 79)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	131	Target Neighborhood Hits	523	Shared Neighborhood Hits	13
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.067330 (rank : 80)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	131	Target Neighborhood Hits	519	Shared Neighborhood Hits	11
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PHF7_MOUSE
NC score	0.066934 (rank : 81)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	131	Target Neighborhood Hits	65	Shared Neighborhood Hits	7
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

MYST3_HUMAN
NC score	0.066557 (rank : 82)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	131	Target Neighborhood Hits	772	Shared Neighborhood Hits	36
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RSF1_HUMAN
NC score	0.066544 (rank : 83)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	131	Target Neighborhood Hits	539	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

MYST3_MOUSE
NC score	0.065158 (rank : 84)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	131	Target Neighborhood Hits	688	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

AIRE_MOUSE
NC score	0.064724 (rank : 85)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	131	Target Neighborhood Hits	196	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PCLO_HUMAN
NC score	0.064581 (rank : 86)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	131	Target Neighborhood Hits	2046	Shared Neighborhood Hits	66
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

SRRM2_MOUSE
NC score	0.064329 (rank : 87)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	131	Target Neighborhood Hits	1470	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PHF20_HUMAN
NC score	0.064233 (rank : 88)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	131	Target Neighborhood Hits	394	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

MYST4_MOUSE
NC score	0.063687 (rank : 89)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	131	Target Neighborhood Hits	416	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

RBBP6_MOUSE
NC score	0.063248 (rank : 90)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	131	Target Neighborhood Hits	1014	Shared Neighborhood Hits	61
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

BAZ1B_MOUSE
NC score	0.062304 (rank : 91)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	131	Target Neighborhood Hits	394	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ1A_HUMAN
NC score	0.062295 (rank : 92)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	131	Target Neighborhood Hits	693	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CBX3_MOUSE
NC score	0.062153 (rank : 93)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	131	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

PF21A_HUMAN
NC score	0.061601 (rank : 94)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	131	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

CBX3_HUMAN
NC score	0.061571 (rank : 95)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	131	Target Neighborhood Hits	36	Shared Neighborhood Hits	5
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

RBBP6_HUMAN
NC score	0.061290 (rank : 96)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	131	Target Neighborhood Hits	1135	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

AFF1_HUMAN
NC score	0.061126 (rank : 97)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	131	Target Neighborhood Hits	506	Shared Neighborhood Hits	37
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

CBX1_HUMAN
NC score	0.060531 (rank : 98)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.060531 (rank : 99)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

PF21A_MOUSE
NC score	0.060136 (rank : 100)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	131	Target Neighborhood Hits	285	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

ANK2_HUMAN
NC score	0.060024 (rank : 101)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	131	Target Neighborhood Hits	1615	Shared Neighborhood Hits	73
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

AIRE_HUMAN
NC score	0.059699 (rank : 102)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	131	Target Neighborhood Hits	144	Shared Neighborhood Hits	10
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

HUCE1_HUMAN
NC score	0.059656 (rank : 103)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	131	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	O43159, Q7KZ78, Q9BVM6	Gene names	KIAA0409
Domain Architecture	No domain graphic available
Description	Cerebral protein 1.

UHRF1_MOUSE
NC score	0.059297 (rank : 104)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	131	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

MBD1_HUMAN
NC score	0.059184 (rank : 105)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	131	Target Neighborhood Hits	77	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UIS9, O15248, O95241, Q7Z7B5, Q8N4W4, Q9UNZ6, Q9UNZ7, Q9UNZ8, Q9UNZ9	Gene names	MBD1, PCM1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1).

ENL_HUMAN
NC score	0.058916 (rank : 106)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	131	Target Neighborhood Hits	305	Shared Neighborhood Hits	22
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

CBX5_HUMAN
NC score	0.058774 (rank : 107)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	10
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

NOLC1_HUMAN
NC score	0.058133 (rank : 108)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	131	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

CBX5_MOUSE
NC score	0.058008 (rank : 109)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	131	Target Neighborhood Hits	67	Shared Neighborhood Hits	8
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

KI67_HUMAN
NC score	0.057903 (rank : 110)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	131	Target Neighborhood Hits	581	Shared Neighborhood Hits	44
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

AFF4_HUMAN
NC score	0.056890 (rank : 111)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	131	Target Neighborhood Hits	611	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

TAF3_MOUSE
NC score	0.056754 (rank : 112)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	131	Target Neighborhood Hits	463	Shared Neighborhood Hits	31
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PF21B_MOUSE
NC score	0.056679 (rank : 113)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	131	Target Neighborhood Hits	278	Shared Neighborhood Hits	18
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

SELPL_MOUSE
NC score	0.056621 (rank : 114)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	131	Target Neighborhood Hits	588	Shared Neighborhood Hits	39
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRRM1_HUMAN
NC score	0.056262 (rank : 115)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	131	Target Neighborhood Hits	690	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

UHRF2_HUMAN
NC score	0.055871 (rank : 116)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	131	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

BAZ2A_HUMAN
NC score	0.055616 (rank : 117)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	131	Target Neighborhood Hits	780	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

AFF4_MOUSE
NC score	0.055332 (rank : 118)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	131	Target Neighborhood Hits	581	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

MAP1B_HUMAN
NC score	0.055219 (rank : 119)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	131	Target Neighborhood Hits	903	Shared Neighborhood Hits	53
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

TARA_HUMAN
NC score	0.054859 (rank : 120)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	131	Target Neighborhood Hits	1626	Shared Neighborhood Hits	66
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

BAZ2B_HUMAN
NC score	0.054663 (rank : 121)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	131	Target Neighborhood Hits	803	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

FA44A_HUMAN
NC score	0.054489 (rank : 122)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	131	Target Neighborhood Hits	280	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NFC6, Q6P0M8	Gene names	FAM44A
Domain Architecture	No domain graphic available
Description	Protein FAM44A.

UHRF1_HUMAN
NC score	0.054371 (rank : 123)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	131	Target Neighborhood Hits	272	Shared Neighborhood Hits	11
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

ACINU_HUMAN
NC score	0.053917 (rank : 124)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	131	Target Neighborhood Hits	828	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

LCP2_HUMAN
NC score	0.053885 (rank : 125)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	131	Target Neighborhood Hits	531	Shared Neighborhood Hits	31
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

TARSH_HUMAN
NC score	0.053844 (rank : 126)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	131	Target Neighborhood Hits	768	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

CXCC1_HUMAN
NC score	0.053791 (rank : 127)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	131	Target Neighborhood Hits	143	Shared Neighborhood Hits	16
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MINT_MOUSE
NC score	0.053773 (rank : 128)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	131	Target Neighborhood Hits	1514	Shared Neighborhood Hits	69
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

BRDT_MOUSE
NC score	0.053718 (rank : 129)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	131	Target Neighborhood Hits	243	Shared Neighborhood Hits	20
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

MBB1A_HUMAN
NC score	0.053706 (rank : 130)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	131	Target Neighborhood Hits	665	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

DNMT1_HUMAN
NC score	0.053569 (rank : 131)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	131	Target Neighborhood Hits	401	Shared Neighborhood Hits	37
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

FA47A_HUMAN
NC score	0.053566 (rank : 132)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	131	Target Neighborhood Hits	451	Shared Neighborhood Hits	33
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

NASP_HUMAN
NC score	0.053373 (rank : 133)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	131	Target Neighborhood Hits	709	Shared Neighborhood Hits	52
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

BAZ2A_MOUSE
NC score	0.053292 (rank : 134)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	131	Target Neighborhood Hits	744	Shared Neighborhood Hits	42
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

PCLO_MOUSE
NC score	0.053287 (rank : 135)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	131	Target Neighborhood Hits	2275	Shared Neighborhood Hits	68
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CXCC1_MOUSE
NC score	0.053229 (rank : 136)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	131	Target Neighborhood Hits	124	Shared Neighborhood Hits	15
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MINT_HUMAN
NC score	0.053172 (rank : 137)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	131	Target Neighborhood Hits	1291	Shared Neighborhood Hits	57
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PRRT3_HUMAN
NC score	0.052928 (rank : 138)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	131	Target Neighborhood Hits	998	Shared Neighborhood Hits	40
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PHF12_HUMAN
NC score	0.052884 (rank : 139)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	131	Target Neighborhood Hits	174	Shared Neighborhood Hits	13
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

JADE2_MOUSE
NC score	0.052791 (rank : 140)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	131	Target Neighborhood Hits	560	Shared Neighborhood Hits	39
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

BRE1B_MOUSE
NC score	0.052672 (rank : 141)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	131	Target Neighborhood Hits	970	Shared Neighborhood Hits	21
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

TAF3_HUMAN
NC score	0.052659 (rank : 142)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	131	Target Neighborhood Hits	568	Shared Neighborhood Hits	38
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

UHRF2_MOUSE
NC score	0.052639 (rank : 143)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	131	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

SFRIP_HUMAN
NC score	0.052609 (rank : 144)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	131	Target Neighborhood Hits	530	Shared Neighborhood Hits	51
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

DDIT3_HUMAN
NC score	0.052580 (rank : 145)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	131	Target Neighborhood Hits	167	Shared Neighborhood Hits	8
SwissProt Accessions	P35638	Gene names	DDIT3, CHOP, GADD153
Domain Architecture
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

MAP1A_HUMAN
NC score	0.052063 (rank : 146)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	131	Target Neighborhood Hits	1626	Shared Neighborhood Hits	72
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PF21B_HUMAN
NC score	0.051731 (rank : 147)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	131	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

K1802_MOUSE
NC score	0.051672 (rank : 148)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	131	Target Neighborhood Hits	1596	Shared Neighborhood Hits	43
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PHF12_MOUSE
NC score	0.051031 (rank : 149)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	131	Target Neighborhood Hits	172	Shared Neighborhood Hits	12
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BRD8_MOUSE
NC score	0.050966 (rank : 150)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	131	Target Neighborhood Hits	422	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

MAP1B_MOUSE
NC score	0.050722 (rank : 151)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	131	Target Neighborhood Hits	977	Shared Neighborhood Hits	52
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MBD1_MOUSE
NC score	0.050306 (rank : 152)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

BRE1B_HUMAN
NC score	0.049657 (rank : 153)	θ value	0.21417 (rank : 35)
Query Neighborhood Hits	131	Target Neighborhood Hits	1040	Shared Neighborhood Hits	32
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

CBP_MOUSE
NC score	0.049578 (rank : 154)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	131	Target Neighborhood Hits	1051	Shared Neighborhood Hits	37
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DDIT3_MOUSE
NC score	0.049475 (rank : 155)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	131	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	P35639, Q91YW9	Gene names	Ddit3, Chop, Gadd153
Domain Architecture	No domain graphic available
Description	DNA damage-inducible transcript 3 (DDIT-3) (Growth arrest and DNA- damage-inducible protein GADD153) (C/EBP-homologous protein) (CHOP).

CT174_HUMAN
NC score	0.048482 (rank : 156)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	131	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q5JPB2, Q5TDR4, Q8TCP0	Gene names	C20orf174
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf174.

ABCF1_HUMAN
NC score	0.047630 (rank : 157)	θ value	0.0330416 (rank : 26)
Query Neighborhood Hits	131	Target Neighborhood Hits	343	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NE71, O14897, Q69YP6	Gene names	ABCF1, ABC50
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein).

XYLT1_MOUSE
NC score	0.046979 (rank : 158)	θ value	0.365318 (rank : 42)
Query Neighborhood Hits	131	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	Q811B1, Q9EPL1	Gene names	Xylt1
Domain Architecture	No domain graphic available
Description	Xylosyltransferase 1 (EC 2.4.2.26) (Xylosyltransferase I) (Peptide O- xylosyltransferase 1).

CHD3_HUMAN
NC score	0.046665 (rank : 159)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	131	Target Neighborhood Hits	397	Shared Neighborhood Hits	21
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

NFH_HUMAN
NC score	0.046549 (rank : 160)	θ value	0.0330416 (rank : 28)
Query Neighborhood Hits	131	Target Neighborhood Hits	1242	Shared Neighborhood Hits	55
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

TTC16_HUMAN
NC score	0.045936 (rank : 161)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	131	Target Neighborhood Hits	417	Shared Neighborhood Hits	38
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

CS016_HUMAN
NC score	0.045575 (rank : 162)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	131	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	Q8ND99	Gene names	C19orf16
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf16.

SMYD1_HUMAN
NC score	0.045137 (rank : 163)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	131	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SYNJ1_HUMAN
NC score	0.043989 (rank : 164)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	131	Target Neighborhood Hits	498	Shared Neighborhood Hits	25
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PRG4_HUMAN
NC score	0.043961 (rank : 165)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	131	Target Neighborhood Hits	764	Shared Neighborhood Hits	35
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

CYLC2_HUMAN
NC score	0.043799 (rank : 166)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	131	Target Neighborhood Hits	223	Shared Neighborhood Hits	17
SwissProt Accessions	Q14093	Gene names	CYLC2, CYL2
Domain Architecture	No domain graphic available
Description	Cylicin-2 (Cylicin II) (Multiple-band polypeptide II).

SNIP_HUMAN
NC score	0.042977 (rank : 167)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	131	Target Neighborhood Hits	313	Shared Neighborhood Hits	21
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

ANR38_MOUSE
NC score	0.041362 (rank : 168)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	131	Target Neighborhood Hits	512	Shared Neighborhood Hits	17
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

MAP2_MOUSE
NC score	0.040843 (rank : 169)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	131	Target Neighborhood Hits	342	Shared Neighborhood Hits	32
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

CCD96_HUMAN
NC score	0.039103 (rank : 170)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	131	Target Neighborhood Hits	595	Shared Neighborhood Hits	20
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

ANR12_HUMAN
NC score	0.036764 (rank : 171)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	131	Target Neighborhood Hits	1081	Shared Neighborhood Hits	50
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

TARA_MOUSE
NC score	0.036248 (rank : 172)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	131	Target Neighborhood Hits	1133	Shared Neighborhood Hits	48
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

INCE_HUMAN
NC score	0.035560 (rank : 173)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	131	Target Neighborhood Hits	978	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

H14_HUMAN
NC score	0.035219 (rank : 174)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	131	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	P10412	Gene names	HIST1H1E, H1F4
Domain Architecture
Description	Histone H1.4 (Histone H1b).

TTF1_MOUSE
NC score	0.034853 (rank : 175)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	30
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

RIMS1_HUMAN
NC score	0.034430 (rank : 176)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	131	Target Neighborhood Hits	437	Shared Neighborhood Hits	20
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

K0690_MOUSE
NC score	0.034102 (rank : 177)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

CKAP5_HUMAN
NC score	0.033404 (rank : 178)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	131	Target Neighborhood Hits	96	Shared Neighborhood Hits	6
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

BRCA2_HUMAN
NC score	0.033093 (rank : 179)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	131	Target Neighborhood Hits	202	Shared Neighborhood Hits	6
SwissProt Accessions	P51587, O00183, O15008, Q13879	Gene names	BRCA2, FANCD1
Domain Architecture
Description	Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein).

THOC2_HUMAN
NC score	0.032786 (rank : 180)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	131	Target Neighborhood Hits	337	Shared Neighborhood Hits	31
SwissProt Accessions	Q8NI27, Q9H8I6	Gene names	THOC2, CXorf3
Domain Architecture	No domain graphic available
Description	THO complex subunit 2 (Tho2).

HCLS1_HUMAN
NC score	0.032183 (rank : 181)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	131	Target Neighborhood Hits	358	Shared Neighborhood Hits	19
SwissProt Accessions	P14317	Gene names	HCLS1, HS1
Domain Architecture
Description	Hematopoietic lineage cell-specific protein (Hematopoietic cell- specific LYN substrate 1) (LckBP1) (p75).

SMRC2_HUMAN
NC score	0.030620 (rank : 182)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	131	Target Neighborhood Hits	499	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

K0690_HUMAN
NC score	0.030607 (rank : 183)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	131	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JTH9, Q5JTH8, Q69YK4, Q96E87, Q9BUH3, Q9Y4C7	Gene names	KIAA0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

TACC2_HUMAN
NC score	0.030348 (rank : 184)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	131	Target Neighborhood Hits	856	Shared Neighborhood Hits	41
SwissProt Accessions	O95359, Q9NZ41, Q9NZR5	Gene names	TACC2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2 (Anti Zuai-1) (AZU-1).

ZC313_HUMAN
NC score	0.030343 (rank : 185)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	131	Target Neighborhood Hits	772	Shared Neighborhood Hits	44
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

CAF1A_HUMAN
NC score	0.029550 (rank : 186)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	131	Target Neighborhood Hits	750	Shared Neighborhood Hits	30
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

IF2P_HUMAN
NC score	0.028735 (rank : 187)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	131	Target Neighborhood Hits	889	Shared Neighborhood Hits	29
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

SCYB9_HUMAN
NC score	0.028170 (rank : 188)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	131	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q07325, Q503B4	Gene names	CXCL9, MIG, SCYB9
Domain Architecture
Description	Small inducible cytokine B9 precursor (CXCL9) (Gamma interferon- induced monokine) (MIG).

SMYD4_HUMAN
NC score	0.027903 (rank : 189)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	131	Target Neighborhood Hits	81	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

MOR2A_MOUSE
NC score	0.026811 (rank : 190)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	131	Target Neighborhood Hits	220	Shared Neighborhood Hits	16
SwissProt Accessions	Q69ZX6, Q5QNQ7, Q6P547	Gene names	Morc2a, Kiaa0852, Zcwcc1
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2A (Zinc finger CW-type coiled-coil domain protein 1).

CNGA1_MOUSE
NC score	0.026586 (rank : 191)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	131	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

ERRFI_MOUSE
NC score	0.026567 (rank : 192)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	131	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q99JZ7	Gene names	Errfi1, Mig6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein homolog) (Mig-6).

RIMS2_HUMAN
NC score	0.026003 (rank : 193)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	131	Target Neighborhood Hits	342	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQ26, O43413, Q86XL9, Q8IWV9, Q8IWW1	Gene names	RIMS2, KIAA0751, RIM2
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 2 (Rab3-interacting molecule 2) (RIM 2).

AP3D1_HUMAN
NC score	0.025290 (rank : 194)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	131	Target Neighborhood Hits	254	Shared Neighborhood Hits	16
SwissProt Accessions	O14617, O00202, O75262, Q59HF5, Q96G11, Q9H3C6	Gene names	AP3D1
Domain Architecture
Description	AP-3 complex subunit delta-1 (Adapter-related protein complex 3 subunit delta-1) (Delta-adaptin 3) (AP-3 complex subunit delta) (Delta-adaptin).

PRP4B_MOUSE
NC score	0.023905 (rank : 195)	θ value	0.0736092 (rank : 30)
Query Neighborhood Hits	131	Target Neighborhood Hits	1040	Shared Neighborhood Hits	29
SwissProt Accessions	Q61136, O88378, Q8BND8, Q8R4Y5, Q9CTL9, Q9CTT0	Gene names	Prpf4b, Cbp143, Prp4h, Prp4k, Prp4m, Prpk
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (Pre-mRNA protein kinase).

TITIN_HUMAN
NC score	0.022610 (rank : 196)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	131	Target Neighborhood Hits	2923	Shared Neighborhood Hits	68
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

LACTB_HUMAN
NC score	0.021078 (rank : 197)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	131	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

CING_MOUSE
NC score	0.021032 (rank : 198)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	131	Target Neighborhood Hits	1432	Shared Neighborhood Hits	42
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

LSR_HUMAN
NC score	0.020860 (rank : 199)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	131	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q86X29, O00112, O00426, Q6ZT80, Q9UQL3	Gene names	LSR, LISCH
Domain Architecture	No domain graphic available
Description	Lipolysis-stimulated lipoprotein receptor.

RBMX2_MOUSE
NC score	0.020833 (rank : 200)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	131	Target Neighborhood Hits	287	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

SEC62_MOUSE
NC score	0.020590 (rank : 201)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	131	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BU14, Q6NX81	Gene names	Tloc1, Sec62
Domain Architecture	No domain graphic available
Description	Translocation protein SEC62 (Translocation protein 1) (TP-1).

CNGA1_HUMAN
NC score	0.020239 (rank : 202)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	131	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

TTC16_MOUSE
NC score	0.019536 (rank : 203)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	131	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

ZN638_MOUSE
NC score	0.019528 (rank : 204)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	131	Target Neighborhood Hits	318	Shared Neighborhood Hits	20
SwissProt Accessions	Q61464, Q6DFV9, Q8C941	Gene names	Znf638, Np220, Zfml
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein).

HMGN3_MOUSE
NC score	0.018810 (rank : 205)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	131	Target Neighborhood Hits	30	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DCB1, Q7M737, Q99JU1	Gene names	Hmgn3
Domain Architecture	No domain graphic available
Description	High mobility group nucleosome-binding domain-containing protein 3.

CHD6_HUMAN
NC score	0.018508 (rank : 206)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	131	Target Neighborhood Hits	342	Shared Neighborhood Hits	33
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CEBPD_MOUSE
NC score	0.018375 (rank : 207)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	131	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q00322	Gene names	Cebpd, Crp3
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (C/EBP-related protein 3).

HMMR_MOUSE
NC score	0.017623 (rank : 208)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	131	Target Neighborhood Hits	1178	Shared Neighborhood Hits	35
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

RENT2_HUMAN
NC score	0.016683 (rank : 209)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	131	Target Neighborhood Hits	618	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

K0831_MOUSE
NC score	0.016093 (rank : 210)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	131	Target Neighborhood Hits	277	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

RBM28_MOUSE
NC score	0.015958 (rank : 211)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	131	Target Neighborhood Hits	368	Shared Neighborhood Hits	22
SwissProt Accessions	Q8CGC6, Q8BG25, Q8VEJ8, Q9CS22, Q9CSE6	Gene names	Rbm28
Domain Architecture	No domain graphic available
Description	RNA-binding protein 28 (RNA-binding motif protein 28).

PRP4B_HUMAN
NC score	0.014538 (rank : 212)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	131	Target Neighborhood Hits	1030	Shared Neighborhood Hits	27
SwissProt Accessions	Q13523, Q8TDP2, Q96QT7, Q9UEE6	Gene names	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K
Domain Architecture
Description	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 pre- mRNA-processing factor 4 homolog) (PRP4 kinase).

DDX46_HUMAN
NC score	0.012409 (rank : 213)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	131	Target Neighborhood Hits	357	Shared Neighborhood Hits	14
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

MK07_MOUSE
NC score	0.011674 (rank : 214)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	131	Target Neighborhood Hits	1054	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MAGI2_HUMAN
NC score	0.010612 (rank : 215)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	131	Target Neighborhood Hits	373	Shared Neighborhood Hits	10
SwissProt Accessions	Q86UL8, O60434, O60510, Q86UI7, Q9NP44, Q9UDQ5, Q9UDU1	Gene names	MAGI2, ACVRINP1, AIP1, KIAA0705
Domain Architecture
Description	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Atrophin-1-interacting protein 1) (Atrophin-1-interacting protein A).

MK07_HUMAN
NC score	0.010183 (rank : 216)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	131	Target Neighborhood Hits	1087	Shared Neighborhood Hits	23
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

DDX46_MOUSE
NC score	0.009151 (rank : 217)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	131	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

MYH11_HUMAN
NC score	0.009137 (rank : 218)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	131	Target Neighborhood Hits	1806	Shared Neighborhood Hits	46
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MINK1_HUMAN
NC score	0.008928 (rank : 219)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	131	Target Neighborhood Hits	1477	Shared Neighborhood Hits	30
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

ATBF1_MOUSE
NC score	0.008646 (rank : 220)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	131	Target Neighborhood Hits	1841	Shared Neighborhood Hits	35
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MYT1L_HUMAN
NC score	0.008023 (rank : 221)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	131	Target Neighborhood Hits	471	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UL68, Q6IQ17, Q9UPP6	Gene names	MYT1L, KIAA1106
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (MyT1-L).

MINK1_MOUSE
NC score	0.007780 (rank : 222)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	131	Target Neighborhood Hits	1451	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MARK2_MOUSE
NC score	0.007588 (rank : 223)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	131	Target Neighborhood Hits	1018	Shared Neighborhood Hits	24
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

MARK2_HUMAN
NC score	0.007266 (rank : 224)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	131	Target Neighborhood Hits	1056	Shared Neighborhood Hits	28
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

STIP1_MOUSE
NC score	0.007024 (rank : 225)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	131	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

FOG1_HUMAN
NC score	0.007006 (rank : 226)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	131	Target Neighborhood Hits	981	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IX07	Gene names	ZFPM1, FOG1
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZFPM1 (Zinc finger protein multitype 1) (Friend of GATA protein 1) (Friend of GATA-1) (FOG-1).

SALL2_MOUSE
NC score	0.003809 (rank : 227)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	131	Target Neighborhood Hits	836	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QX96	Gene names	Sall2, Sal2
Domain Architecture	No domain graphic available
Description	Sal-like protein 2 (Spalt-like protein 2) (MSal-2).

M4K2_HUMAN
NC score	0.003390 (rank : 228)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	131	Target Neighborhood Hits	850	Shared Neighborhood Hits	9
SwissProt Accessions	Q12851	Gene names	MAP4K2, GCK, RAB8IP
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Germinal center kinase) (GC kinase) (Rab8-interacting protein) (B lymphocyte serine/threonine-protein kinase).