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Network neighborhood for query Sequence : PHF7_MOUSE

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PHF7_MOUSE
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PHF7_MOUSE
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_HUMAN
θ value	3.37019e-164 (rank : 2)	NC score	0.988000 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

K1333_HUMAN
θ value	6.98233e-69 (rank : 3)	NC score	0.891860 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	1.31681e-67 (rank : 4)	NC score	0.891432 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PHF6_HUMAN
θ value	8.67504e-11 (rank : 5)	NC score	0.604817 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	8.67504e-11 (rank : 6)	NC score	0.600002 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF11_HUMAN
θ value	4.0297e-08 (rank : 7)	NC score	0.604029 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

MLL3_MOUSE
θ value	6.43352e-06 (rank : 8)	NC score	0.256492 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	1399	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
θ value	2.44474e-05 (rank : 9)	NC score	0.241478 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	1644	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

HRX_HUMAN
θ value	5.44631e-05 (rank : 10)	NC score	0.305109 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	825	Shared Neighborhood Hits	50
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
θ value	9.29e-05 (rank : 11)	NC score	0.316413 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	722	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

JADE1_HUMAN
θ value	0.000602161 (rank : 12)	NC score	0.299153 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	140	Shared Neighborhood Hits	46
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

BRPF3_HUMAN
θ value	0.00102713 (rank : 13)	NC score	0.254518 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

JADE1_MOUSE
θ value	0.00175202 (rank : 14)	NC score	0.297411 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	160	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

RAI1_HUMAN
θ value	0.00665767 (rank : 15)	NC score	0.286527 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

JADE3_HUMAN
θ value	0.00869519 (rank : 16)	NC score	0.279927 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

BRD1_HUMAN
θ value	0.0113563 (rank : 17)	NC score	0.250455 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
θ value	0.0193708 (rank : 18)	NC score	0.249524 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	259	Shared Neighborhood Hits	44
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JADE3_MOUSE
θ value	0.0252991 (rank : 19)	NC score	0.280183 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	174	Shared Neighborhood Hits	46
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

NSD1_MOUSE
θ value	0.0252991 (rank : 20)	NC score	0.169005 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	472	Shared Neighborhood Hits	41
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RAI1_MOUSE
θ value	0.0252991 (rank : 21)	NC score	0.283245 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	344	Shared Neighborhood Hits	39
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TCF20_HUMAN
θ value	0.0252991 (rank : 22)	NC score	0.269299 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

NSD1_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.163674 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	427	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

TCF20_MOUSE
θ value	0.0330416 (rank : 24)	NC score	0.253716 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	396	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

JHD3A_HUMAN
θ value	0.0563607 (rank : 25)	NC score	0.187020 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	31
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
θ value	0.0736092 (rank : 26)	NC score	0.186691 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

AF10_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.224139 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.224237 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	182	Shared Neighborhood Hits	38
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

JADE2_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.267238 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.246962 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JHD3C_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.175761 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

K1802_HUMAN
θ value	0.279714 (rank : 32)	NC score	0.048624 (rank : 95)
Query Neighborhood Hits	65	Target Neighborhood Hits	1378	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

NFX1_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.054493 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	405	Shared Neighborhood Hits	14
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

JHD3C_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.173393 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

K1802_MOUSE
θ value	0.365318 (rank : 35)	NC score	0.051106 (rank : 91)
Query Neighborhood Hits	65	Target Neighborhood Hits	1596	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL2_HUMAN
θ value	0.365318 (rank : 36)	NC score	0.208960 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	1788	Shared Neighborhood Hits	51
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHF14_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.214398 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	447	Shared Neighborhood Hits	41
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	0.365318 (rank : 38)	NC score	0.218750 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

JHD3B_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.191441 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	128	Shared Neighborhood Hits	38
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.189309 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

MYST3_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.107480 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	772	Shared Neighborhood Hits	36
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

AF17_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.224634 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

MYST3_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.107723 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	688	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

DZIP3_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.043358 (rank : 99)
Query Neighborhood Hits	65	Target Neighborhood Hits	399	Shared Neighborhood Hits	4
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

DZIP3_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.044224 (rank : 98)
Query Neighborhood Hits	65	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

MYST4_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.112064 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	671	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.117659 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	416	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PF21A_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.109132 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	285	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PCGF2_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.046824 (rank : 97)
Query Neighborhood Hits	65	Target Neighborhood Hits	222	Shared Neighborhood Hits	6
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.046896 (rank : 96)
Query Neighborhood Hits	65	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

ZFP28_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.001935 (rank : 108)
Query Neighborhood Hits	65	Target Neighborhood Hits	843	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

LETM1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.023408 (rank : 103)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

PF21A_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.105197 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RXINP_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.037613 (rank : 100)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

MTF2_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.101840 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	3.0926 (rank : 56)	NC score	0.102880 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

ZFP28_MOUSE
θ value	3.0926 (rank : 57)	NC score	0.001033 (rank : 109)
Query Neighborhood Hits	65	Target Neighborhood Hits	782	Shared Neighborhood Hits	8
SwissProt Accessions	P10078, Q61776, Q8BT11, Q8C836	Gene names	Zfp28, Mkr5, Zfp-28
Domain Architecture
Description	Zinc finger protein 28 (Zfp-28) (Protein mKR5).

DLL1_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.004035 (rank : 107)
Query Neighborhood Hits	65	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

ZN198_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.013378 (rank : 105)
Query Neighborhood Hits	65	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

FRAS1_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.017276 (rank : 104)
Query Neighborhood Hits	65	Target Neighborhood Hits	759	Shared Neighborhood Hits	14
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

PCGF4_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.033540 (rank : 101)
Query Neighborhood Hits	65	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.033503 (rank : 102)
Query Neighborhood Hits	65	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

LYZL4_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.009746 (rank : 106)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KX0	Gene names	LYZL4, LYC4
Domain Architecture	No domain graphic available
Description	Lysozyme-like protein 4 precursor.

PRD15_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.000622 (rank : 110)
Query Neighborhood Hits	65	Target Neighborhood Hits	805	Shared Neighborhood Hits	7
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

TYK2_MOUSE
θ value	8.99809 (rank : 65)	NC score	-0.002139 (rank : 111)
Query Neighborhood Hits	65	Target Neighborhood Hits	850	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

AIRE_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.079003 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.079544 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	196	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.063039 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.059248 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	701	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.064073 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.052457 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	780	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.050729 (rank : 93)
Query Neighborhood Hits	65	Target Neighborhood Hits	744	Shared Neighborhood Hits	32
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.054825 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	803	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.055384 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	786	Shared Neighborhood Hits	27
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

DPF1_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.082554 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	136	Shared Neighborhood Hits	27
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.081542 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

EZH1_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.065634 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.065595 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.066462 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.066024 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

JAD1A_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.077069 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	328	Shared Neighborhood Hits	33
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1C_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.070673 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.070310 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	164	Shared Neighborhood Hits	31
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.075343 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
θ value	θ > 10 (rank : 85)	NC score	0.066285 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	228	Shared Neighborhood Hits	33
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JHD3D_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.068814 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.069111 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

PF21B_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.053836 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.056871 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.114976 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.113830 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF12_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.061327 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	174	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.059874 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	172	Shared Neighborhood Hits	26
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF1_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.088937 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.088663 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	116	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PKCB1_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.051377 (rank : 90)
Query Neighborhood Hits	65	Target Neighborhood Hits	488	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

REQU_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.078670 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	523	Shared Neighborhood Hits	29
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.077766 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	519	Shared Neighborhood Hits	29
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.061936 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	539	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SET1A_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.091923 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	690	Shared Neighborhood Hits	14
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETB2_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.050589 (rank : 94)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETD2_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.078811 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	412	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SETD8_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.068996 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.066934 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SUV91_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.058682 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.057732 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.062694 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.060667 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

UHRF1_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.050835 (rank : 92)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.053520 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.057102 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

Hits sorted by NC score

PHF7_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_HUMAN
NC score	0.988000 (rank : 2)	θ value	3.37019e-164 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	71	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

K1333_HUMAN
NC score	0.891860 (rank : 3)	θ value	6.98233e-69 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	30
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
NC score	0.891432 (rank : 4)	θ value	1.31681e-67 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	53	Shared Neighborhood Hits	33
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

PHF6_HUMAN
NC score	0.604817 (rank : 5)	θ value	8.67504e-11 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF11_HUMAN
NC score	0.604029 (rank : 6)	θ value	4.0297e-08 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	42	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF6_MOUSE
NC score	0.600002 (rank : 7)	θ value	8.67504e-11 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	39	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

MLL4_HUMAN
NC score	0.316413 (rank : 8)	θ value	9.29e-05 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	722	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.305109 (rank : 9)	θ value	5.44631e-05 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	825	Shared Neighborhood Hits	50
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

JADE1_HUMAN
NC score	0.299153 (rank : 10)	θ value	0.000602161 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	140	Shared Neighborhood Hits	46
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.297411 (rank : 11)	θ value	0.00175202 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	160	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

RAI1_HUMAN
NC score	0.286527 (rank : 12)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	360	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
NC score	0.283245 (rank : 13)	θ value	0.0252991 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	344	Shared Neighborhood Hits	39
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

JADE3_MOUSE
NC score	0.280183 (rank : 14)	θ value	0.0252991 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	174	Shared Neighborhood Hits	46
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_HUMAN
NC score	0.279927 (rank : 15)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	148	Shared Neighborhood Hits	47
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

TCF20_HUMAN
NC score	0.269299 (rank : 16)	θ value	0.0252991 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	323	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

JADE2_HUMAN
NC score	0.267238 (rank : 17)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

MLL3_MOUSE
NC score	0.256492 (rank : 18)	θ value	6.43352e-06 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	1399	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

BRPF3_HUMAN
NC score	0.254518 (rank : 19)	θ value	0.00102713 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	217	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

TCF20_MOUSE
NC score	0.253716 (rank : 20)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	396	Shared Neighborhood Hits	34
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

BRD1_HUMAN
NC score	0.250455 (rank : 21)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	188	Shared Neighborhood Hits	43
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF1_HUMAN
NC score	0.249524 (rank : 22)	θ value	0.0193708 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	259	Shared Neighborhood Hits	44
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

JADE2_MOUSE
NC score	0.246962 (rank : 23)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	560	Shared Neighborhood Hits	48
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

MLL3_HUMAN
NC score	0.241478 (rank : 24)	θ value	2.44474e-05 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	1644	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AF17_HUMAN
NC score	0.224634 (rank : 25)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	230	Shared Neighborhood Hits	38
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

AF10_MOUSE
NC score	0.224237 (rank : 26)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	182	Shared Neighborhood Hits	38
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
NC score	0.224139 (rank : 27)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	198	Shared Neighborhood Hits	38
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

PHF14_MOUSE
NC score	0.218750 (rank : 28)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	342	Shared Neighborhood Hits	41
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.214398 (rank : 29)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	447	Shared Neighborhood Hits	41
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

MLL2_HUMAN
NC score	0.208960 (rank : 30)	θ value	0.365318 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	1788	Shared Neighborhood Hits	51
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

JHD3B_HUMAN
NC score	0.191441 (rank : 31)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	128	Shared Neighborhood Hits	38
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
NC score	0.189309 (rank : 32)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3A_HUMAN
NC score	0.187020 (rank : 33)	θ value	0.0563607 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	78	Shared Neighborhood Hits	31
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3A_MOUSE
NC score	0.186691 (rank : 34)	θ value	0.0736092 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	85	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_MOUSE
NC score	0.175761 (rank : 35)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3C_HUMAN
NC score	0.173393 (rank : 36)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

NSD1_MOUSE
NC score	0.169005 (rank : 37)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	472	Shared Neighborhood Hits	41
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

NSD1_HUMAN
NC score	0.163674 (rank : 38)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	427	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MYST4_MOUSE
NC score	0.117659 (rank : 39)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	416	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PHF10_HUMAN
NC score	0.114976 (rank : 40)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	65	Target Neighborhood Hits	151	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.113830 (rank : 41)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	29
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

MYST4_HUMAN
NC score	0.112064 (rank : 42)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	671	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PF21A_MOUSE
NC score	0.109132 (rank : 43)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	285	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

MYST3_MOUSE
NC score	0.107723 (rank : 44)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	688	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST3_HUMAN
NC score	0.107480 (rank : 45)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	772	Shared Neighborhood Hits	36
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PF21A_HUMAN
NC score	0.105197 (rank : 46)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	303	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

MTF2_MOUSE
NC score	0.102880 (rank : 47)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	126	Shared Neighborhood Hits	29
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_HUMAN
NC score	0.101840 (rank : 48)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

SET1A_HUMAN
NC score	0.091923 (rank : 49)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	65	Target Neighborhood Hits	690	Shared Neighborhood Hits	14
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PHF1_HUMAN
NC score	0.088937 (rank : 50)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	65	Target Neighborhood Hits	117	Shared Neighborhood Hits	28
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
NC score	0.088663 (rank : 51)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	65	Target Neighborhood Hits	116	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

DPF1_HUMAN
NC score	0.082554 (rank : 52)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	136	Shared Neighborhood Hits	27
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
NC score	0.081542 (rank : 53)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

AIRE_MOUSE
NC score	0.079544 (rank : 54)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	196	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.079003 (rank : 55)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	144	Shared Neighborhood Hits	29
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

SETD2_HUMAN
NC score	0.078811 (rank : 56)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	65	Target Neighborhood Hits	412	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

REQU_HUMAN
NC score	0.078670 (rank : 57)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	65	Target Neighborhood Hits	523	Shared Neighborhood Hits	29
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.077766 (rank : 58)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	65	Target Neighborhood Hits	519	Shared Neighborhood Hits	29
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

JAD1A_HUMAN
NC score	0.077069 (rank : 59)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	328	Shared Neighborhood Hits	33
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1D_HUMAN
NC score	0.075343 (rank : 60)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1C_HUMAN
NC score	0.070673 (rank : 61)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	187	Shared Neighborhood Hits	32
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
NC score	0.070310 (rank : 62)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	164	Shared Neighborhood Hits	31
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JHD3D_MOUSE
NC score	0.069111 (rank : 63)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

SETD8_HUMAN
NC score	0.068996 (rank : 64)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	65	Target Neighborhood Hits	114	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

JHD3D_HUMAN
NC score	0.068814 (rank : 65)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	6
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

SETD8_MOUSE
NC score	0.066934 (rank : 66)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	65	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

EZH2_HUMAN
NC score	0.066462 (rank : 67)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	84	Shared Neighborhood Hits	8
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

JAD1D_MOUSE
NC score	0.066285 (rank : 68)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	228	Shared Neighborhood Hits	33
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

EZH2_MOUSE
NC score	0.066024 (rank : 69)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	8
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_HUMAN
NC score	0.065634 (rank : 70)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.065595 (rank : 71)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	126	Shared Neighborhood Hits	8
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

BAZ1B_MOUSE
NC score	0.064073 (rank : 72)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	394	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ1A_HUMAN
NC score	0.063039 (rank : 73)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	693	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

SUV92_HUMAN
NC score	0.062694 (rank : 74)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

RSF1_HUMAN
NC score	0.061936 (rank : 75)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	65	Target Neighborhood Hits	539	Shared Neighborhood Hits	27
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PHF12_HUMAN
NC score	0.061327 (rank : 76)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	65	Target Neighborhood Hits	174	Shared Neighborhood Hits	27
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

SUV92_MOUSE
NC score	0.060667 (rank : 77)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	65	Target Neighborhood Hits	59	Shared Neighborhood Hits	7
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

PHF12_MOUSE
NC score	0.059874 (rank : 78)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	65	Target Neighborhood Hits	172	Shared Neighborhood Hits	26
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BAZ1B_HUMAN
NC score	0.059248 (rank : 79)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	701	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

SUV91_HUMAN
NC score	0.058682 (rank : 80)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	65	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
NC score	0.057732 (rank : 81)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	65	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

UHRF2_MOUSE
NC score	0.057102 (rank : 82)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

PF21B_MOUSE
NC score	0.056871 (rank : 83)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BPTF_HUMAN
NC score	0.055384 (rank : 84)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	786	Shared Neighborhood Hits	27
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BAZ2B_HUMAN
NC score	0.054825 (rank : 85)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	803	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

NFX1_HUMAN
NC score	0.054493 (rank : 86)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	405	Shared Neighborhood Hits	14
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

PF21B_HUMAN
NC score	0.053836 (rank : 87)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	197	Shared Neighborhood Hits	18
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

UHRF2_HUMAN
NC score	0.053520 (rank : 88)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	65	Target Neighborhood Hits	269	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

BAZ2A_HUMAN
NC score	0.052457 (rank : 89)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	780	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PKCB1_HUMAN
NC score	0.051377 (rank : 90)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	65	Target Neighborhood Hits	488	Shared Neighborhood Hits	30
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

K1802_MOUSE
NC score	0.051106 (rank : 91)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	1596	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

UHRF1_MOUSE
NC score	0.050835 (rank : 92)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	65	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

BAZ2A_MOUSE
NC score	0.050729 (rank : 93)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	744	Shared Neighborhood Hits	32
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

SETB2_HUMAN
NC score	0.050589 (rank : 94)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

K1802_HUMAN
NC score	0.048624 (rank : 95)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	1378	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PCGF2_MOUSE
NC score	0.046896 (rank : 96)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	213	Shared Neighborhood Hits	6
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF2_HUMAN
NC score	0.046824 (rank : 97)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	222	Shared Neighborhood Hits	6
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

DZIP3_MOUSE
NC score	0.044224 (rank : 98)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	414	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TPV2, Q80TU4, Q8BYK7	Gene names	Dzip3, Kiaa0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3 homolog).

DZIP3_HUMAN
NC score	0.043358 (rank : 99)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	399	Shared Neighborhood Hits	4
SwissProt Accessions	Q86Y13, O75162, Q6P3R9, Q6PH82, Q86Y14, Q86Y15, Q86Y16, Q8IWI0, Q96RS9	Gene names	DZIP3, KIAA0675
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein DZIP3 (EC 6.3.2.-) (DAZ-interacting protein 3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138).

RXINP_MOUSE
NC score	0.037613 (rank : 100)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q5U5Q9, Q60811	Gene names	Rxrip110, Rip110
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110.

PCGF4_HUMAN
NC score	0.033540 (rank : 101)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	161	Shared Neighborhood Hits	5
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.033503 (rank : 102)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

LETM1_MOUSE
NC score	0.023408 (rank : 103)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

FRAS1_HUMAN
NC score	0.017276 (rank : 104)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	759	Shared Neighborhood Hits	14
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ZN198_HUMAN
NC score	0.013378 (rank : 105)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBW7, O43212, O43434, O60898, Q5W0Q4, Q63HP0, Q8NE39, Q9H538, Q9UEU2	Gene names	ZNF198, FIM, RAMP, ZMYM2
Domain Architecture
Description	Zinc finger protein 198 (Zinc finger MYM-type protein 2) (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein).

LYZL4_HUMAN
NC score	0.009746 (rank : 106)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q96KX0	Gene names	LYZL4, LYC4
Domain Architecture	No domain graphic available
Description	Lysozyme-like protein 4 precursor.

DLL1_HUMAN
NC score	0.004035 (rank : 107)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	455	Shared Neighborhood Hits	6
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

ZFP28_HUMAN
NC score	0.001935 (rank : 108)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	843	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

ZFP28_MOUSE
NC score	0.001033 (rank : 109)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	782	Shared Neighborhood Hits	8
SwissProt Accessions	P10078, Q61776, Q8BT11, Q8C836	Gene names	Zfp28, Mkr5, Zfp-28
Domain Architecture
Description	Zinc finger protein 28 (Zfp-28) (Protein mKR5).

PRD15_HUMAN
NC score	0.000622 (rank : 110)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	805	Shared Neighborhood Hits	7
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

TYK2_MOUSE
NC score	-0.002139 (rank : 111)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	850	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).