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Network neighborhood for query Sequence : JAD1C_HUMAN

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JAD1C_HUMAN
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

JAD1A_HUMAN
θ value	0 (rank : 1)	NC score	0.965513 (rank : 5)
Query Neighborhood Hits	187	Target Neighborhood Hits	328	Shared Neighborhood Hits	117
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JAD1C_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	187	Target Neighborhood Hits	187	Shared Neighborhood Hits	187
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	0 (rank : 3)	NC score	0.996855 (rank : 2)
Query Neighborhood Hits	187	Target Neighborhood Hits	164	Shared Neighborhood Hits	144
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
θ value	0 (rank : 4)	NC score	0.989798 (rank : 3)
Query Neighborhood Hits	187	Target Neighborhood Hits	147	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
θ value	0 (rank : 5)	NC score	0.984129 (rank : 4)
Query Neighborhood Hits	187	Target Neighborhood Hits	228	Shared Neighborhood Hits	122
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JARD2_MOUSE
θ value	2.96089e-35 (rank : 6)	NC score	0.664251 (rank : 9)
Query Neighborhood Hits	187	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JARD2_HUMAN
θ value	6.59618e-35 (rank : 7)	NC score	0.673388 (rank : 7)
Query Neighborhood Hits	187	Target Neighborhood Hits	119	Shared Neighborhood Hits	28
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3D_MOUSE
θ value	6.59618e-35 (rank : 8)	NC score	0.674892 (rank : 6)
Query Neighborhood Hits	187	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3D_HUMAN
θ value	1.24399e-33 (rank : 9)	NC score	0.670857 (rank : 8)
Query Neighborhood Hits	187	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JHD3A_MOUSE
θ value	1.79631e-32 (rank : 10)	NC score	0.617743 (rank : 10)
Query Neighborhood Hits	187	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_MOUSE
θ value	1.79631e-32 (rank : 11)	NC score	0.616320 (rank : 11)
Query Neighborhood Hits	187	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3C_HUMAN
θ value	2.34606e-32 (rank : 12)	NC score	0.610902 (rank : 13)
Query Neighborhood Hits	187	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3A_HUMAN
θ value	3.06405e-32 (rank : 13)	NC score	0.615767 (rank : 12)
Query Neighborhood Hits	187	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3B_HUMAN
θ value	7.54701e-31 (rank : 14)	NC score	0.606841 (rank : 14)
Query Neighborhood Hits	187	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
θ value	9.8567e-31 (rank : 15)	NC score	0.606681 (rank : 15)
Query Neighborhood Hits	187	Target Neighborhood Hits	152	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

BAZ1B_HUMAN
θ value	7.84624e-12 (rank : 16)	NC score	0.391513 (rank : 31)
Query Neighborhood Hits	187	Target Neighborhood Hits	701	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	2.98157e-11 (rank : 17)	NC score	0.422686 (rank : 20)
Query Neighborhood Hits	187	Target Neighborhood Hits	394	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

MLL2_HUMAN
θ value	6.64225e-11 (rank : 18)	NC score	0.334843 (rank : 45)
Query Neighborhood Hits	187	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DPF1_MOUSE
θ value	1.133e-10 (rank : 19)	NC score	0.406769 (rank : 24)
Query Neighborhood Hits	187	Target Neighborhood Hits	491	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL3_HUMAN
θ value	1.47974e-10 (rank : 20)	NC score	0.321147 (rank : 48)
Query Neighborhood Hits	187	Target Neighborhood Hits	1644	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	1.47974e-10 (rank : 21)	NC score	0.339981 (rank : 43)
Query Neighborhood Hits	187	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

CHD4_HUMAN
θ value	1.9326e-10 (rank : 22)	NC score	0.266585 (rank : 61)
Query Neighborhood Hits	187	Target Neighborhood Hits	365	Shared Neighborhood Hits	94
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	1.9326e-10 (rank : 23)	NC score	0.266149 (rank : 62)
Query Neighborhood Hits	187	Target Neighborhood Hits	408	Shared Neighborhood Hits	95
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	1.9326e-10 (rank : 24)	NC score	0.268950 (rank : 59)
Query Neighborhood Hits	187	Target Neighborhood Hits	349	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

REQU_MOUSE
θ value	4.30538e-10 (rank : 25)	NC score	0.402841 (rank : 26)
Query Neighborhood Hits	187	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

CHD3_HUMAN
θ value	5.62301e-10 (rank : 26)	NC score	0.264701 (rank : 64)
Query Neighborhood Hits	187	Target Neighborhood Hits	397	Shared Neighborhood Hits	90
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

REQU_HUMAN
θ value	5.62301e-10 (rank : 27)	NC score	0.404422 (rank : 25)
Query Neighborhood Hits	187	Target Neighborhood Hits	523	Shared Neighborhood Hits	74
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

BAZ2A_HUMAN
θ value	2.79066e-09 (rank : 28)	NC score	0.351953 (rank : 37)
Query Neighborhood Hits	187	Target Neighborhood Hits	780	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	2.79066e-09 (rank : 29)	NC score	0.349959 (rank : 41)
Query Neighborhood Hits	187	Target Neighborhood Hits	744	Shared Neighborhood Hits	93
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST4_MOUSE
θ value	8.11959e-09 (rank : 30)	NC score	0.345601 (rank : 42)
Query Neighborhood Hits	187	Target Neighborhood Hits	416	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

AIRE_MOUSE
θ value	1.06045e-08 (rank : 31)	NC score	0.451445 (rank : 17)
Query Neighborhood Hits	187	Target Neighborhood Hits	196	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MYST4_HUMAN
θ value	1.06045e-08 (rank : 32)	NC score	0.333807 (rank : 46)
Query Neighborhood Hits	187	Target Neighborhood Hits	671	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

AIRE_HUMAN
θ value	2.36244e-08 (rank : 33)	NC score	0.464331 (rank : 16)
Query Neighborhood Hits	187	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

ARI3A_MOUSE
θ value	2.36244e-08 (rank : 34)	NC score	0.373101 (rank : 34)
Query Neighborhood Hits	187	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

BAZ1A_HUMAN
θ value	3.08544e-08 (rank : 35)	NC score	0.377443 (rank : 33)
Query Neighborhood Hits	187	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

DPF1_HUMAN
θ value	3.08544e-08 (rank : 36)	NC score	0.426629 (rank : 19)
Query Neighborhood Hits	187	Target Neighborhood Hits	136	Shared Neighborhood Hits	69
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

ARI3A_HUMAN
θ value	5.26297e-08 (rank : 37)	NC score	0.367132 (rank : 35)
Query Neighborhood Hits	187	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

MYST3_HUMAN
θ value	5.26297e-08 (rank : 38)	NC score	0.319159 (rank : 49)
Query Neighborhood Hits	187	Target Neighborhood Hits	772	Shared Neighborhood Hits	104
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	6.87365e-08 (rank : 39)	NC score	0.319077 (rank : 50)
Query Neighborhood Hits	187	Target Neighborhood Hits	688	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PF21A_MOUSE
θ value	1.99992e-07 (rank : 40)	NC score	0.427540 (rank : 18)
Query Neighborhood Hits	187	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
θ value	2.61198e-07 (rank : 41)	NC score	0.421103 (rank : 21)
Query Neighborhood Hits	187	Target Neighborhood Hits	303	Shared Neighborhood Hits	79
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

UHRF1_HUMAN
θ value	2.61198e-07 (rank : 42)	NC score	0.365586 (rank : 36)
Query Neighborhood Hits	187	Target Neighborhood Hits	272	Shared Neighborhood Hits	72
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

RSF1_HUMAN
θ value	3.41135e-07 (rank : 43)	NC score	0.391697 (rank : 30)
Query Neighborhood Hits	187	Target Neighborhood Hits	539	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

UHRF2_HUMAN
θ value	5.81887e-07 (rank : 44)	NC score	0.339389 (rank : 44)
Query Neighborhood Hits	187	Target Neighborhood Hits	269	Shared Neighborhood Hits	70
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

BPTF_HUMAN
θ value	9.92553e-07 (rank : 45)	NC score	0.316500 (rank : 51)
Query Neighborhood Hits	187	Target Neighborhood Hits	786	Shared Neighborhood Hits	103
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

UHRF1_MOUSE
θ value	1.29631e-06 (rank : 46)	NC score	0.350317 (rank : 39)
Query Neighborhood Hits	187	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

ARI4A_HUMAN
θ value	2.21117e-06 (rank : 47)	NC score	0.265969 (rank : 63)
Query Neighborhood Hits	187	Target Neighborhood Hits	434	Shared Neighborhood Hits	34
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ARI5B_MOUSE
θ value	2.88788e-06 (rank : 48)	NC score	0.256047 (rank : 67)
Query Neighborhood Hits	187	Target Neighborhood Hits	158	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

PF21B_HUMAN
θ value	3.77169e-06 (rank : 49)	NC score	0.401247 (rank : 28)
Query Neighborhood Hits	187	Target Neighborhood Hits	197	Shared Neighborhood Hits	67
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

UHRF2_MOUSE
θ value	4.92598e-06 (rank : 50)	NC score	0.325643 (rank : 47)
Query Neighborhood Hits	187	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

PF21B_MOUSE
θ value	8.40245e-06 (rank : 51)	NC score	0.390881 (rank : 32)
Query Neighborhood Hits	187	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_MOUSE
θ value	8.40245e-06 (rank : 52)	NC score	0.411914 (rank : 22)
Query Neighborhood Hits	187	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF14_HUMAN
θ value	8.40245e-06 (rank : 53)	NC score	0.394443 (rank : 29)
Query Neighborhood Hits	187	Target Neighborhood Hits	447	Shared Neighborhood Hits	94
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	8.40245e-06 (rank : 54)	NC score	0.401327 (rank : 27)
Query Neighborhood Hits	187	Target Neighborhood Hits	342	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF10_HUMAN
θ value	1.87187e-05 (rank : 55)	NC score	0.408586 (rank : 23)
Query Neighborhood Hits	187	Target Neighborhood Hits	151	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

ARI1A_HUMAN
θ value	2.44474e-05 (rank : 56)	NC score	0.210743 (rank : 85)
Query Neighborhood Hits	187	Target Neighborhood Hits	787	Shared Neighborhood Hits	40
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ARI5B_HUMAN
θ value	2.44474e-05 (rank : 57)	NC score	0.246927 (rank : 69)
Query Neighborhood Hits	187	Target Neighborhood Hits	328	Shared Neighborhood Hits	34
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ARI1B_HUMAN
θ value	5.44631e-05 (rank : 58)	NC score	0.233368 (rank : 77)
Query Neighborhood Hits	187	Target Neighborhood Hits	567	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

ARID2_HUMAN
θ value	5.44631e-05 (rank : 59)	NC score	0.263486 (rank : 65)
Query Neighborhood Hits	187	Target Neighborhood Hits	302	Shared Neighborhood Hits	24
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

PHF12_HUMAN
θ value	0.00035302 (rank : 60)	NC score	0.349999 (rank : 40)
Query Neighborhood Hits	187	Target Neighborhood Hits	174	Shared Neighborhood Hits	74
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	0.00035302 (rank : 61)	NC score	0.351059 (rank : 38)
Query Neighborhood Hits	187	Target Neighborhood Hits	172	Shared Neighborhood Hits	70
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

NSD1_MOUSE
θ value	0.00175202 (rank : 62)	NC score	0.223211 (rank : 81)
Query Neighborhood Hits	187	Target Neighborhood Hits	472	Shared Neighborhood Hits	83
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TRI66_MOUSE
θ value	0.00175202 (rank : 63)	NC score	0.267817 (rank : 60)
Query Neighborhood Hits	187	Target Neighborhood Hits	491	Shared Neighborhood Hits	73
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1A_HUMAN
θ value	0.00390308 (rank : 64)	NC score	0.240675 (rank : 73)
Query Neighborhood Hits	187	Target Neighborhood Hits	327	Shared Neighborhood Hits	78
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	0.00390308 (rank : 65)	NC score	0.242245 (rank : 71)
Query Neighborhood Hits	187	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_HUMAN
θ value	0.00390308 (rank : 66)	NC score	0.236906 (rank : 76)
Query Neighborhood Hits	187	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	0.00390308 (rank : 67)	NC score	0.239688 (rank : 75)
Query Neighborhood Hits	187	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI66_HUMAN
θ value	0.00509761 (rank : 68)	NC score	0.259598 (rank : 66)
Query Neighborhood Hits	187	Target Neighborhood Hits	479	Shared Neighborhood Hits	78
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PHF20_MOUSE
θ value	0.00665767 (rank : 69)	NC score	0.132365 (rank : 102)
Query Neighborhood Hits	187	Target Neighborhood Hits	513	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TAF3_HUMAN
θ value	0.00665767 (rank : 70)	NC score	0.213972 (rank : 84)
Query Neighborhood Hits	187	Target Neighborhood Hits	568	Shared Neighborhood Hits	86
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PHF8_HUMAN
θ value	0.00869519 (rank : 71)	NC score	0.135188 (rank : 98)
Query Neighborhood Hits	187	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

PHF20_HUMAN
θ value	0.0113563 (rank : 72)	NC score	0.135220 (rank : 97)
Query Neighborhood Hits	187	Target Neighborhood Hits	394	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

RGS3_HUMAN
θ value	0.0113563 (rank : 73)	NC score	0.035580 (rank : 186)
Query Neighborhood Hits	187	Target Neighborhood Hits	1375	Shared Neighborhood Hits	49
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

JADE3_MOUSE
θ value	0.0148317 (rank : 74)	NC score	0.273229 (rank : 55)
Query Neighborhood Hits	187	Target Neighborhood Hits	174	Shared Neighborhood Hits	82
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

K1718_HUMAN
θ value	0.0148317 (rank : 75)	NC score	0.134528 (rank : 99)
Query Neighborhood Hits	187	Target Neighborhood Hits	114	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

JADE1_HUMAN
θ value	0.0193708 (rank : 76)	NC score	0.269902 (rank : 56)
Query Neighborhood Hits	187	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	0.0193708 (rank : 77)	NC score	0.269430 (rank : 58)
Query Neighborhood Hits	187	Target Neighborhood Hits	160	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

K1718_MOUSE
θ value	0.0193708 (rank : 78)	NC score	0.133610 (rank : 101)
Query Neighborhood Hits	187	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF8_MOUSE
θ value	0.0193708 (rank : 79)	NC score	0.132322 (rank : 103)
Query Neighborhood Hits	187	Target Neighborhood Hits	96	Shared Neighborhood Hits	35
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

TIF1G_HUMAN
θ value	0.0193708 (rank : 80)	NC score	0.217801 (rank : 83)
Query Neighborhood Hits	187	Target Neighborhood Hits	410	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.0193708 (rank : 81)	NC score	0.218329 (rank : 82)
Query Neighborhood Hits	187	Target Neighborhood Hits	498	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

BRPF1_HUMAN
θ value	0.0252991 (rank : 82)	NC score	0.295814 (rank : 52)
Query Neighborhood Hits	187	Target Neighborhood Hits	259	Shared Neighborhood Hits	87
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

CROCC_MOUSE
θ value	0.0252991 (rank : 83)	NC score	0.023506 (rank : 202)
Query Neighborhood Hits	187	Target Neighborhood Hits	1460	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DIDO1_HUMAN
θ value	0.0330416 (rank : 84)	NC score	0.138292 (rank : 96)
Query Neighborhood Hits	187	Target Neighborhood Hits	960	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

LAMC2_HUMAN
θ value	0.0736092 (rank : 85)	NC score	0.017518 (rank : 210)
Query Neighborhood Hits	187	Target Neighborhood Hits	715	Shared Neighborhood Hits	26
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

NSD1_HUMAN
θ value	0.0736092 (rank : 86)	NC score	0.207955 (rank : 86)
Query Neighborhood Hits	187	Target Neighborhood Hits	427	Shared Neighborhood Hits	81
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PKCB1_HUMAN
θ value	0.0736092 (rank : 87)	NC score	0.241565 (rank : 72)
Query Neighborhood Hits	187	Target Neighborhood Hits	488	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

LAMB1_HUMAN
θ value	0.0961366 (rank : 88)	NC score	0.016640 (rank : 214)
Query Neighborhood Hits	187	Target Neighborhood Hits	1018	Shared Neighborhood Hits	28
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BRD1_HUMAN
θ value	0.125558 (rank : 89)	NC score	0.283675 (rank : 54)
Query Neighborhood Hits	187	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

PHF2_HUMAN
θ value	0.125558 (rank : 90)	NC score	0.129360 (rank : 105)
Query Neighborhood Hits	187	Target Neighborhood Hits	208	Shared Neighborhood Hits	42
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
θ value	0.125558 (rank : 91)	NC score	0.128554 (rank : 106)
Query Neighborhood Hits	187	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

JADE3_HUMAN
θ value	0.163984 (rank : 92)	NC score	0.269509 (rank : 57)
Query Neighborhood Hits	187	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

SPTA1_HUMAN
θ value	0.163984 (rank : 93)	NC score	0.025647 (rank : 198)
Query Neighborhood Hits	187	Target Neighborhood Hits	748	Shared Neighborhood Hits	21
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

BPAEA_HUMAN
θ value	0.279714 (rank : 94)	NC score	0.032175 (rank : 189)
Query Neighborhood Hits	187	Target Neighborhood Hits	1369	Shared Neighborhood Hits	42
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

LY10_HUMAN
θ value	0.279714 (rank : 95)	NC score	0.206304 (rank : 87)
Query Neighborhood Hits	187	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

PLEC1_HUMAN
θ value	0.279714 (rank : 96)	NC score	0.025924 (rank : 197)
Query Neighborhood Hits	187	Target Neighborhood Hits	1326	Shared Neighborhood Hits	45
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

TAF3_MOUSE
θ value	0.279714 (rank : 97)	NC score	0.198944 (rank : 88)
Query Neighborhood Hits	187	Target Neighborhood Hits	463	Shared Neighborhood Hits	83
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CXCC1_HUMAN
θ value	0.365318 (rank : 98)	NC score	0.163831 (rank : 92)
Query Neighborhood Hits	187	Target Neighborhood Hits	143	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	0.365318 (rank : 99)	NC score	0.160871 (rank : 93)
Query Neighborhood Hits	187	Target Neighborhood Hits	124	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CYLD_MOUSE
θ value	0.365318 (rank : 100)	NC score	0.062576 (rank : 143)
Query Neighborhood Hits	187	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

OGFR_MOUSE
θ value	0.365318 (rank : 101)	NC score	0.039459 (rank : 183)
Query Neighborhood Hits	187	Target Neighborhood Hits	584	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

TXND2_HUMAN
θ value	0.365318 (rank : 102)	NC score	0.059524 (rank : 151)
Query Neighborhood Hits	187	Target Neighborhood Hits	793	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BEGIN_HUMAN
θ value	0.47712 (rank : 103)	NC score	0.026034 (rank : 196)
Query Neighborhood Hits	187	Target Neighborhood Hits	454	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

HOOK2_HUMAN
θ value	0.47712 (rank : 104)	NC score	0.015537 (rank : 217)
Query Neighborhood Hits	187	Target Neighborhood Hits	714	Shared Neighborhood Hits	29
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

OGFR_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.037276 (rank : 184)
Query Neighborhood Hits	187	Target Neighborhood Hits	1582	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

SYNE2_HUMAN
θ value	0.62314 (rank : 106)	NC score	0.028588 (rank : 191)
Query Neighborhood Hits	187	Target Neighborhood Hits	1323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

DDX21_HUMAN
θ value	0.813845 (rank : 107)	NC score	0.016654 (rank : 213)
Query Neighborhood Hits	187	Target Neighborhood Hits	308	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

IF16_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.019675 (rank : 206)
Query Neighborhood Hits	187	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

MACF1_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.027675 (rank : 194)
Query Neighborhood Hits	187	Target Neighborhood Hits	1341	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.813845 (rank : 110)	NC score	0.031230 (rank : 190)
Query Neighborhood Hits	187	Target Neighborhood Hits	1321	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

BAZ2B_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.287554 (rank : 53)
Query Neighborhood Hits	187	Target Neighborhood Hits	803	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPA1_MOUSE
θ value	1.06291 (rank : 112)	NC score	0.028157 (rank : 192)
Query Neighborhood Hits	187	Target Neighborhood Hits	1477	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

KI67_HUMAN
θ value	1.06291 (rank : 113)	NC score	0.047620 (rank : 182)
Query Neighborhood Hits	187	Target Neighborhood Hits	581	Shared Neighborhood Hits	36
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MARH4_HUMAN
θ value	1.06291 (rank : 114)	NC score	0.079764 (rank : 119)
Query Neighborhood Hits	187	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2E8, Q86WR8	Gene names	MARCH4, KIAA1399, RNF174
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 4 (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174).

MARH4_MOUSE
θ value	1.06291 (rank : 115)	NC score	0.087355 (rank : 118)
Query Neighborhood Hits	187	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q80TE3	Gene names	March4, Kiaa1399
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 4 (Membrane-associated RING-CH protein IV) (MARCH-IV).

MFAP1_HUMAN
θ value	1.06291 (rank : 116)	NC score	0.059938 (rank : 150)
Query Neighborhood Hits	187	Target Neighborhood Hits	321	Shared Neighborhood Hits	20
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

MFAP1_MOUSE
θ value	1.06291 (rank : 117)	NC score	0.057125 (rank : 157)
Query Neighborhood Hits	187	Target Neighborhood Hits	353	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

PAK3_MOUSE
θ value	1.06291 (rank : 118)	NC score	-0.001112 (rank : 245)
Query Neighborhood Hits	187	Target Neighborhood Hits	874	Shared Neighborhood Hits	7
SwissProt Accessions	Q61036, O88645, Q8K1R5, Q8K1R6	Gene names	Pak3, Pak-3, Pakb, Stk4
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B).

PRIMA_HUMAN
θ value	1.06291 (rank : 119)	NC score	0.032626 (rank : 187)
Query Neighborhood Hits	187	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XR5, Q86XR6	Gene names	PRIMA1
Domain Architecture	No domain graphic available
Description	Proline-rich membrane anchor 1 precursor (PRiMA).

AF10_HUMAN
θ value	1.38821 (rank : 120)	NC score	0.225586 (rank : 80)
Query Neighborhood Hits	187	Target Neighborhood Hits	198	Shared Neighborhood Hits	54
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

AF10_MOUSE
θ value	1.38821 (rank : 121)	NC score	0.225843 (rank : 79)
Query Neighborhood Hits	187	Target Neighborhood Hits	182	Shared Neighborhood Hits	54
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

BEGIN_MOUSE
θ value	1.38821 (rank : 122)	NC score	0.022386 (rank : 203)
Query Neighborhood Hits	187	Target Neighborhood Hits	383	Shared Neighborhood Hits	14
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CYLD_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.053234 (rank : 172)
Query Neighborhood Hits	187	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

ING3_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.103402 (rank : 112)
Query Neighborhood Hits	187	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

MTF2_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.158291 (rank : 94)
Query Neighborhood Hits	187	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	1.38821 (rank : 126)	NC score	0.157611 (rank : 95)
Query Neighborhood Hits	187	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PAK3_HUMAN
θ value	1.38821 (rank : 127)	NC score	-0.001820 (rank : 247)
Query Neighborhood Hits	187	Target Neighborhood Hits	887	Shared Neighborhood Hits	7
SwissProt Accessions	O75914, Q5JWX1, Q5JWX2, Q7Z2D6, Q7Z2E4, Q7Z3Z8, Q8WWK5, Q8WX23, Q9P0J8	Gene names	PAK3, OPHN3
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3).

PHF3_HUMAN
θ value	1.38821 (rank : 128)	NC score	0.103631 (rank : 111)
Query Neighborhood Hits	187	Target Neighborhood Hits	419	Shared Neighborhood Hits	54
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ZN385_HUMAN
θ value	1.38821 (rank : 129)	NC score	0.012177 (rank : 226)
Query Neighborhood Hits	187	Target Neighborhood Hits	614	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

AF17_HUMAN
θ value	1.81305 (rank : 130)	NC score	0.242990 (rank : 70)
Query Neighborhood Hits	187	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

ING3_MOUSE
θ value	1.81305 (rank : 131)	NC score	0.095988 (rank : 115)
Query Neighborhood Hits	187	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

PCNT_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.024082 (rank : 201)
Query Neighborhood Hits	187	Target Neighborhood Hits	1551	Shared Neighborhood Hits	50
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TRIPB_HUMAN
θ value	1.81305 (rank : 133)	NC score	0.027704 (rank : 193)
Query Neighborhood Hits	187	Target Neighborhood Hits	1587	Shared Neighborhood Hits	61
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ATX7_HUMAN
θ value	2.36792 (rank : 134)	NC score	0.027430 (rank : 195)
Query Neighborhood Hits	187	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BBS2_MOUSE
θ value	2.36792 (rank : 135)	NC score	0.037020 (rank : 185)
Query Neighborhood Hits	187	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CWF6	Gene names	Bbs2
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 2 protein homolog.

CE290_HUMAN
θ value	2.36792 (rank : 136)	NC score	0.022049 (rank : 204)
Query Neighborhood Hits	187	Target Neighborhood Hits	1553	Shared Neighborhood Hits	54
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

IP6K3_MOUSE
θ value	2.36792 (rank : 137)	NC score	0.014208 (rank : 220)
Query Neighborhood Hits	187	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWD2	Gene names	Ihpk3, Ip6k3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

JHD1A_HUMAN
θ value	2.36792 (rank : 138)	NC score	0.075793 (rank : 121)
Query Neighborhood Hits	187	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

SYTL1_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.007727 (rank : 238)
Query Neighborhood Hits	187	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

TMC1_MOUSE
θ value	2.36792 (rank : 140)	NC score	0.021299 (rank : 205)
Query Neighborhood Hits	187	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4P5, Q9D435	Gene names	Tmc1, Bth, dn
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 1 (Beethoven protein) (Deafness protein).

AKAP9_HUMAN
θ value	3.0926 (rank : 141)	NC score	0.019574 (rank : 207)
Query Neighborhood Hits	187	Target Neighborhood Hits	1710	Shared Neighborhood Hits	53
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

B4GT1_HUMAN
θ value	3.0926 (rank : 142)	NC score	0.010434 (rank : 232)
Query Neighborhood Hits	187	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

ING5_HUMAN
θ value	3.0926 (rank : 143)	NC score	0.096027 (rank : 114)
Query Neighborhood Hits	187	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING5_MOUSE
θ value	3.0926 (rank : 144)	NC score	0.088833 (rank : 117)
Query Neighborhood Hits	187	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

MLL4_HUMAN
θ value	3.0926 (rank : 145)	NC score	0.187687 (rank : 89)
Query Neighborhood Hits	187	Target Neighborhood Hits	722	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SEBP2_HUMAN
θ value	3.0926 (rank : 146)	NC score	0.016730 (rank : 212)
Query Neighborhood Hits	187	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

TCF20_HUMAN
θ value	3.0926 (rank : 147)	NC score	0.049244 (rank : 181)
Query Neighborhood Hits	187	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

BBS2_HUMAN
θ value	4.03905 (rank : 148)	NC score	0.032352 (rank : 188)
Query Neighborhood Hits	187	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXC9, Q96CM0, Q96SN9	Gene names	BBS2
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 2 protein.

CTDP1_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.012050 (rank : 227)
Query Neighborhood Hits	187	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

DDX49_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.005417 (rank : 239)
Query Neighborhood Hits	187	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

I11RB_MOUSE
θ value	4.03905 (rank : 151)	NC score	0.014922 (rank : 218)
Query Neighborhood Hits	187	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

JHD1A_MOUSE
θ value	4.03905 (rank : 152)	NC score	0.071739 (rank : 122)
Query Neighborhood Hits	187	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

MSLN_HUMAN
θ value	4.03905 (rank : 153)	NC score	0.012671 (rank : 224)
Query Neighborhood Hits	187	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q13421, Q14859, Q4VQD5, Q96GR6, Q96KJ5, Q9BR17, Q9BTR2, Q9UK57	Gene names	MSLN, MPF
Domain Architecture
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) (CAK1 antigen) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

PRIMA_MOUSE
θ value	4.03905 (rank : 154)	NC score	0.025210 (rank : 199)
Query Neighborhood Hits	187	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q810F0, Q8VHC4	Gene names	Prima1
Domain Architecture	No domain graphic available
Description	Proline-rich membrane anchor 1 precursor (PRiMA).

STXB4_MOUSE
θ value	4.03905 (rank : 155)	NC score	0.008318 (rank : 236)
Query Neighborhood Hits	187	Target Neighborhood Hits	629	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

ZN688_HUMAN
θ value	4.03905 (rank : 156)	NC score	-0.004343 (rank : 250)
Query Neighborhood Hits	187	Target Neighborhood Hits	873	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

ZO1_HUMAN
θ value	4.03905 (rank : 157)	NC score	0.009412 (rank : 234)
Query Neighborhood Hits	187	Target Neighborhood Hits	474	Shared Neighborhood Hits	16
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

AATK_HUMAN
θ value	5.27518 (rank : 158)	NC score	-0.001749 (rank : 246)
Query Neighborhood Hits	187	Target Neighborhood Hits	1243	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

CN130_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.055354 (rank : 163)
Query Neighborhood Hits	187	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

CN130_MOUSE
θ value	5.27518 (rank : 160)	NC score	0.056766 (rank : 159)
Query Neighborhood Hits	187	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

CXA4_MOUSE
θ value	5.27518 (rank : 161)	NC score	0.002609 (rank : 242)
Query Neighborhood Hits	187	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P28235	Gene names	Gja4, Cxn-37
Domain Architecture
Description	Gap junction alpha-4 protein (Connexin-37) (Cx37).

ELL_HUMAN
θ value	5.27518 (rank : 162)	NC score	0.009260 (rank : 235)
Query Neighborhood Hits	187	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

KTN1_MOUSE
θ value	5.27518 (rank : 163)	NC score	0.018168 (rank : 209)
Query Neighborhood Hits	187	Target Neighborhood Hits	1324	Shared Neighborhood Hits	53
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

SPTA2_HUMAN
θ value	5.27518 (rank : 164)	NC score	0.017148 (rank : 211)
Query Neighborhood Hits	187	Target Neighborhood Hits	888	Shared Neighborhood Hits	27
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

TCF19_HUMAN
θ value	5.27518 (rank : 165)	NC score	0.133626 (rank : 100)
Query Neighborhood Hits	187	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

CROCC_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.013915 (rank : 222)
Query Neighborhood Hits	187	Target Neighborhood Hits	1409	Shared Neighborhood Hits	41
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

FINC_MOUSE
θ value	6.88961 (rank : 167)	NC score	0.000965 (rank : 243)
Query Neighborhood Hits	187	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MY18A_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.018652 (rank : 208)
Query Neighborhood Hits	187	Target Neighborhood Hits	1929	Shared Neighborhood Hits	60
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

OBSCN_HUMAN
θ value	6.88961 (rank : 169)	NC score	-0.002769 (rank : 248)
Query Neighborhood Hits	187	Target Neighborhood Hits	1931	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

OXRP_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.014147 (rank : 221)
Query Neighborhood Hits	187	Target Neighborhood Hits	544	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RIMB1_HUMAN
θ value	6.88961 (rank : 171)	NC score	0.012478 (rank : 225)
Query Neighborhood Hits	187	Target Neighborhood Hits	1479	Shared Neighborhood Hits	46
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

STX1A_HUMAN
θ value	6.88961 (rank : 172)	NC score	0.013497 (rank : 223)
Query Neighborhood Hits	187	Target Neighborhood Hits	266	Shared Neighborhood Hits	16
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

STX1A_MOUSE
θ value	6.88961 (rank : 173)	NC score	0.014276 (rank : 219)
Query Neighborhood Hits	187	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

SYFB_HUMAN
θ value	6.88961 (rank : 174)	NC score	0.011024 (rank : 229)
Query Neighborhood Hits	187	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSD9, O95708, Q9NZZ6	Gene names	FARSLB, FARSB, FRSB
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

TLE4_HUMAN
θ value	6.88961 (rank : 175)	NC score	0.002775 (rank : 241)
Query Neighborhood Hits	187	Target Neighborhood Hits	477	Shared Neighborhood Hits	7
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

TLE4_MOUSE
θ value	6.88961 (rank : 176)	NC score	0.002790 (rank : 240)
Query Neighborhood Hits	187	Target Neighborhood Hits	482	Shared Neighborhood Hits	7
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TNR22_MOUSE
θ value	6.88961 (rank : 177)	NC score	0.010747 (rank : 231)
Query Neighborhood Hits	187	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

U171_HUMAN
θ value	6.88961 (rank : 178)	NC score	0.024853 (rank : 200)
Query Neighborhood Hits	187	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q12980, Q4TT56, Q92469	Gene names	CGTHBA, C16orf35
Domain Architecture
Description	CGTHBA protein (-14 gene protein).

I11RA_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.011139 (rank : 228)
Query Neighborhood Hits	187	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

IF4G1_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.010748 (rank : 230)
Query Neighborhood Hits	187	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K0427_MOUSE
θ value	8.99809 (rank : 181)	NC score	0.007733 (rank : 237)
Query Neighborhood Hits	187	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

MUC1_HUMAN
θ value	8.99809 (rank : 182)	NC score	0.015593 (rank : 216)
Query Neighborhood Hits	187	Target Neighborhood Hits	975	Shared Neighborhood Hits	29
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MYPT2_HUMAN
θ value	8.99809 (rank : 183)	NC score	-0.000307 (rank : 244)
Query Neighborhood Hits	187	Target Neighborhood Hits	707	Shared Neighborhood Hits	17
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PRDM1_MOUSE
θ value	8.99809 (rank : 184)	NC score	-0.004741 (rank : 251)
Query Neighborhood Hits	187	Target Neighborhood Hits	766	Shared Neighborhood Hits	6
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

SPTB2_HUMAN
θ value	8.99809 (rank : 185)	NC score	0.016636 (rank : 215)
Query Neighborhood Hits	187	Target Neighborhood Hits	748	Shared Neighborhood Hits	26
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SYFB_MOUSE
θ value	8.99809 (rank : 186)	NC score	0.010125 (rank : 233)
Query Neighborhood Hits	187	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUA2	Gene names	Farslb, Farsb, Farsl, Frsb
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

ZN438_HUMAN
θ value	8.99809 (rank : 187)	NC score	-0.003598 (rank : 249)
Query Neighborhood Hits	187	Target Neighborhood Hits	906	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ATRX_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.055891 (rank : 161)
Query Neighborhood Hits	187	Target Neighborhood Hits	842	Shared Neighborhood Hits	59
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

ATRX_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.058699 (rank : 153)
Query Neighborhood Hits	187	Target Neighborhood Hits	682	Shared Neighborhood Hits	48
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

BRD2_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.059225 (rank : 152)
Query Neighborhood Hits	187	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.058478 (rank : 156)
Query Neighborhood Hits	187	Target Neighborhood Hits	369	Shared Neighborhood Hits	36
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.056841 (rank : 158)
Query Neighborhood Hits	187	Target Neighborhood Hits	402	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.064845 (rank : 139)
Query Neighborhood Hits	187	Target Neighborhood Hits	851	Shared Neighborhood Hits	56
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.065560 (rank : 137)
Query Neighborhood Hits	187	Target Neighborhood Hits	845	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD8_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.064679 (rank : 140)
Query Neighborhood Hits	187	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRD8_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.066252 (rank : 135)
Query Neighborhood Hits	187	Target Neighborhood Hits	422	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

BRDT_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.053667 (rank : 169)
Query Neighborhood Hits	187	Target Neighborhood Hits	280	Shared Neighborhood Hits	28
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.052604 (rank : 174)
Query Neighborhood Hits	187	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BRPF3_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.246996 (rank : 68)
Query Neighborhood Hits	187	Target Neighborhood Hits	217	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CBP_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.054171 (rank : 166)
Query Neighborhood Hits	187	Target Neighborhood Hits	941	Shared Neighborhood Hits	53
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.055050 (rank : 164)
Query Neighborhood Hits	187	Target Neighborhood Hits	1051	Shared Neighborhood Hits	55
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.078032 (rank : 120)
Query Neighborhood Hits	187	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD1_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.050721 (rank : 179)
Query Neighborhood Hits	187	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.051136 (rank : 176)
Query Neighborhood Hits	187	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.053625 (rank : 170)
Query Neighborhood Hits	187	Target Neighborhood Hits	360	Shared Neighborhood Hits	22
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

CHD6_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.054117 (rank : 167)
Query Neighborhood Hits	187	Target Neighborhood Hits	342	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.050870 (rank : 178)
Query Neighborhood Hits	187	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.051070 (rank : 177)
Query Neighborhood Hits	187	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.051268 (rank : 175)
Query Neighborhood Hits	187	Target Neighborhood Hits	427	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

DPF3_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.096955 (rank : 113)
Query Neighborhood Hits	187	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

DPF3_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.114186 (rank : 108)
Query Neighborhood Hits	187	Target Neighborhood Hits	327	Shared Neighborhood Hits	13
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

EP300_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.056164 (rank : 160)
Query Neighborhood Hits	187	Target Neighborhood Hits	821	Shared Neighborhood Hits	43
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GCNL2_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.064375 (rank : 142)
Query Neighborhood Hits	187	Target Neighborhood Hits	159	Shared Neighborhood Hits	23
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.064655 (rank : 141)
Query Neighborhood Hits	187	Target Neighborhood Hits	146	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

HRX_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.179502 (rank : 90)
Query Neighborhood Hits	187	Target Neighborhood Hits	825	Shared Neighborhood Hits	87
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ING1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.061321 (rank : 147)
Query Neighborhood Hits	187	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.061692 (rank : 145)
Query Neighborhood Hits	187	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING2_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.068744 (rank : 127)
Query Neighborhood Hits	187	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

ING2_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.070238 (rank : 124)
Query Neighborhood Hits	187	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

ING4_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.060545 (rank : 148)
Query Neighborhood Hits	187	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.059984 (rank : 149)
Query Neighborhood Hits	187	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

JADE2_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.239706 (rank : 74)
Query Neighborhood Hits	187	Target Neighborhood Hits	199	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.226330 (rank : 78)
Query Neighborhood Hits	187	Target Neighborhood Hits	560	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JHD1B_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.054427 (rank : 165)
Query Neighborhood Hits	187	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.054005 (rank : 168)
Query Neighborhood Hits	187	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MYST1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.067993 (rank : 129)
Query Neighborhood Hits	187	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.068060 (rank : 128)
Query Neighborhood Hits	187	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

MYST2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.067511 (rank : 132)
Query Neighborhood Hits	187	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.067485 (rank : 133)
Query Neighborhood Hits	187	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

PCAF_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.065614 (rank : 136)
Query Neighborhood Hits	187	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PHF11_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.090735 (rank : 116)
Query Neighborhood Hits	187	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF13_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.068837 (rank : 126)
Query Neighborhood Hits	187	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PHF13_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.070225 (rank : 125)
Query Neighborhood Hits	187	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

PHF1_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.108462 (rank : 110)
Query Neighborhood Hits	187	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.109739 (rank : 109)
Query Neighborhood Hits	187	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF22_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.062170 (rank : 144)
Query Neighborhood Hits	187	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.058520 (rank : 155)
Query Neighborhood Hits	187	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF7_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.061520 (rank : 146)
Query Neighborhood Hits	187	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.070673 (rank : 123)
Query Neighborhood Hits	187	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

RAI1_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.050175 (rank : 180)
Query Neighborhood Hits	187	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.053558 (rank : 171)
Query Neighborhood Hits	187	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SET1A_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.058683 (rank : 154)
Query Neighborhood Hits	187	Target Neighborhood Hits	690	Shared Neighborhood Hits	35
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SMCA2_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.065338 (rank : 138)
Query Neighborhood Hits	187	Target Neighborhood Hits	503	Shared Neighborhood Hits	36
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.066316 (rank : 134)
Query Neighborhood Hits	187	Target Neighborhood Hits	597	Shared Neighborhood Hits	41
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SP110_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.167705 (rank : 91)
Query Neighborhood Hits	187	Target Neighborhood Hits	141	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TAF1L_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.052658 (rank : 173)
Query Neighborhood Hits	187	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.055526 (rank : 162)
Query Neighborhood Hits	187	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TIP60_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.067836 (rank : 130)
Query Neighborhood Hits	187	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.067787 (rank : 131)
Query Neighborhood Hits	187	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

ZMY11_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.125434 (rank : 107)
Query Neighborhood Hits	187	Target Neighborhood Hits	201	Shared Neighborhood Hits	58
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.130726 (rank : 104)
Query Neighborhood Hits	187	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

JAD1C_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	187	Target Neighborhood Hits	187	Shared Neighborhood Hits	187
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
NC score	0.996855 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	187	Target Neighborhood Hits	164	Shared Neighborhood Hits	144
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
NC score	0.989798 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	187	Target Neighborhood Hits	147	Shared Neighborhood Hits	116
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
NC score	0.984129 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	187	Target Neighborhood Hits	228	Shared Neighborhood Hits	122
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1A_HUMAN
NC score	0.965513 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	187	Target Neighborhood Hits	328	Shared Neighborhood Hits	117
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JHD3D_MOUSE
NC score	0.674892 (rank : 6)	θ value	6.59618e-35 (rank : 8)
Query Neighborhood Hits	187	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q3U2K5, Q2M1G7, Q8BI19	Gene names	Jmjd2d, Jhdm3d
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JARD2_HUMAN
NC score	0.673388 (rank : 7)	θ value	6.59618e-35 (rank : 7)
Query Neighborhood Hits	187	Target Neighborhood Hits	119	Shared Neighborhood Hits	28
SwissProt Accessions	Q92833, Q5U5L5	Gene names	JARID2, JMJ
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3D_HUMAN
NC score	0.670857 (rank : 8)	θ value	1.24399e-33 (rank : 9)
Query Neighborhood Hits	187	Target Neighborhood Hits	47	Shared Neighborhood Hits	16
SwissProt Accessions	Q6B0I6, Q9NT41, Q9NW76	Gene names	JMJD2D, JHDM3D
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3D (EC 1.14.11.-) (Jumonji domain-containing protein 2D).

JARD2_MOUSE
NC score	0.664251 (rank : 9)	θ value	2.96089e-35 (rank : 6)
Query Neighborhood Hits	187	Target Neighborhood Hits	169	Shared Neighborhood Hits	29
SwissProt Accessions	Q62315, Q99LD1	Gene names	Jarid2, Jmj
Domain Architecture
Description	Jumonji protein (Jumonji/ARID domain-containing protein 2).

JHD3A_MOUSE
NC score	0.617743 (rank : 10)	θ value	1.79631e-32 (rank : 10)
Query Neighborhood Hits	187	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_MOUSE
NC score	0.616320 (rank : 11)	θ value	1.79631e-32 (rank : 11)
Query Neighborhood Hits	187	Target Neighborhood Hits	84	Shared Neighborhood Hits	33
SwissProt Accessions	Q8VCD7, Q3UNP7, Q69ZZ5, Q8BUY6, Q8BWA1	Gene names	Jmjd2c, Jhdm3c, Kiaa0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C).

JHD3A_HUMAN
NC score	0.615767 (rank : 12)	θ value	3.06405e-32 (rank : 13)
Query Neighborhood Hits	187	Target Neighborhood Hits	78	Shared Neighborhood Hits	38
SwissProt Accessions	O75164, Q5VVB1	Gene names	JMJD2A, JHDM3A, JMJD2, KIAA0677
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

JHD3C_HUMAN
NC score	0.610902 (rank : 13)	θ value	2.34606e-32 (rank : 12)
Query Neighborhood Hits	187	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q9H3R0, O94877, Q2M3M0, Q5JUC9, Q5VYJ2, Q5VYJ3	Gene names	JMJD2C, GASC1, JHDM3C, KIAA0780
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3C (EC 1.14.11.-) (Jumonji domain-containing protein 2C) (Gene amplified in squamous cell carcinoma 1 protein) (GASC-1 protein).

JHD3B_HUMAN
NC score	0.606841 (rank : 14)	θ value	7.54701e-31 (rank : 14)
Query Neighborhood Hits	187	Target Neighborhood Hits	128	Shared Neighborhood Hits	40
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

JHD3B_MOUSE
NC score	0.606681 (rank : 15)	θ value	9.8567e-31 (rank : 15)
Query Neighborhood Hits	187	Target Neighborhood Hits	152	Shared Neighborhood Hits	39
SwissProt Accessions	Q91VY5, Q3UR22, Q6ZQ30, Q99K42	Gene names	Jmjd2b, Jhdm3b
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

AIRE_HUMAN
NC score	0.464331 (rank : 16)	θ value	2.36244e-08 (rank : 33)
Query Neighborhood Hits	187	Target Neighborhood Hits	144	Shared Neighborhood Hits	76
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
NC score	0.451445 (rank : 17)	θ value	1.06045e-08 (rank : 31)
Query Neighborhood Hits	187	Target Neighborhood Hits	196	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

PF21A_MOUSE
NC score	0.427540 (rank : 18)	θ value	1.99992e-07 (rank : 40)
Query Neighborhood Hits	187	Target Neighborhood Hits	285	Shared Neighborhood Hits	80
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

DPF1_HUMAN
NC score	0.426629 (rank : 19)	θ value	3.08544e-08 (rank : 36)
Query Neighborhood Hits	187	Target Neighborhood Hits	136	Shared Neighborhood Hits	69
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

BAZ1B_MOUSE
NC score	0.422686 (rank : 20)	θ value	2.98157e-11 (rank : 17)
Query Neighborhood Hits	187	Target Neighborhood Hits	394	Shared Neighborhood Hits	86
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

PF21A_HUMAN
NC score	0.421103 (rank : 21)	θ value	2.61198e-07 (rank : 41)
Query Neighborhood Hits	187	Target Neighborhood Hits	303	Shared Neighborhood Hits	79
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PHF10_MOUSE
NC score	0.411914 (rank : 22)	θ value	8.40245e-06 (rank : 52)
Query Neighborhood Hits	187	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF10_HUMAN
NC score	0.408586 (rank : 23)	θ value	1.87187e-05 (rank : 55)
Query Neighborhood Hits	187	Target Neighborhood Hits	151	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

DPF1_MOUSE
NC score	0.406769 (rank : 24)	θ value	1.133e-10 (rank : 19)
Query Neighborhood Hits	187	Target Neighborhood Hits	491	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

REQU_HUMAN
NC score	0.404422 (rank : 25)	θ value	5.62301e-10 (rank : 27)
Query Neighborhood Hits	187	Target Neighborhood Hits	523	Shared Neighborhood Hits	74
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
NC score	0.402841 (rank : 26)	θ value	4.30538e-10 (rank : 25)
Query Neighborhood Hits	187	Target Neighborhood Hits	519	Shared Neighborhood Hits	72
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PHF14_MOUSE
NC score	0.401327 (rank : 27)	θ value	8.40245e-06 (rank : 54)
Query Neighborhood Hits	187	Target Neighborhood Hits	342	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PF21B_HUMAN
NC score	0.401247 (rank : 28)	θ value	3.77169e-06 (rank : 49)
Query Neighborhood Hits	187	Target Neighborhood Hits	197	Shared Neighborhood Hits	67
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF14_HUMAN
NC score	0.394443 (rank : 29)	θ value	8.40245e-06 (rank : 53)
Query Neighborhood Hits	187	Target Neighborhood Hits	447	Shared Neighborhood Hits	94
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

RSF1_HUMAN
NC score	0.391697 (rank : 30)	θ value	3.41135e-07 (rank : 43)
Query Neighborhood Hits	187	Target Neighborhood Hits	539	Shared Neighborhood Hits	91
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

BAZ1B_HUMAN
NC score	0.391513 (rank : 31)	θ value	7.84624e-12 (rank : 16)
Query Neighborhood Hits	187	Target Neighborhood Hits	701	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

PF21B_MOUSE
NC score	0.390881 (rank : 32)	θ value	8.40245e-06 (rank : 51)
Query Neighborhood Hits	187	Target Neighborhood Hits	278	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

BAZ1A_HUMAN
NC score	0.377443 (rank : 33)	θ value	3.08544e-08 (rank : 35)
Query Neighborhood Hits	187	Target Neighborhood Hits	693	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

ARI3A_MOUSE
NC score	0.373101 (rank : 34)	θ value	2.36244e-08 (rank : 34)
Query Neighborhood Hits	187	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q62431	Gene names	Arid3a, Dri1, Dril1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (Dead ringer-like protein 1) (B-cell regulator of IgH transcription) (Bright).

ARI3A_HUMAN
NC score	0.367132 (rank : 35)	θ value	5.26297e-08 (rank : 37)
Query Neighborhood Hits	187	Target Neighborhood Hits	80	Shared Neighborhood Hits	18
SwissProt Accessions	Q99856, Q8IZA7	Gene names	ARID3A, DRIL1, DRX, E2FBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 3A (ARID domain- containing protein 3A) (B-cell regulator of IgH transcription) (Bright) (E2F-binding protein 1).

UHRF1_HUMAN
NC score	0.365586 (rank : 36)	θ value	2.61198e-07 (rank : 42)
Query Neighborhood Hits	187	Target Neighborhood Hits	272	Shared Neighborhood Hits	72
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

BAZ2A_HUMAN
NC score	0.351953 (rank : 37)	θ value	2.79066e-09 (rank : 28)
Query Neighborhood Hits	187	Target Neighborhood Hits	780	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PHF12_MOUSE
NC score	0.351059 (rank : 38)	θ value	0.00035302 (rank : 61)
Query Neighborhood Hits	187	Target Neighborhood Hits	172	Shared Neighborhood Hits	70
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

UHRF1_MOUSE
NC score	0.350317 (rank : 39)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	187	Target Neighborhood Hits	278	Shared Neighborhood Hits	68
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

PHF12_HUMAN
NC score	0.349999 (rank : 40)	θ value	0.00035302 (rank : 60)
Query Neighborhood Hits	187	Target Neighborhood Hits	174	Shared Neighborhood Hits	74
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BAZ2A_MOUSE
NC score	0.349959 (rank : 41)	θ value	2.79066e-09 (rank : 29)
Query Neighborhood Hits	187	Target Neighborhood Hits	744	Shared Neighborhood Hits	93
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

MYST4_MOUSE
NC score	0.345601 (rank : 42)	θ value	8.11959e-09 (rank : 30)
Query Neighborhood Hits	187	Target Neighborhood Hits	416	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

MLL3_MOUSE
NC score	0.339981 (rank : 43)	θ value	1.47974e-10 (rank : 21)
Query Neighborhood Hits	187	Target Neighborhood Hits	1399	Shared Neighborhood Hits	110
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

UHRF2_HUMAN
NC score	0.339389 (rank : 44)	θ value	5.81887e-07 (rank : 44)
Query Neighborhood Hits	187	Target Neighborhood Hits	269	Shared Neighborhood Hits	70
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

MLL2_HUMAN
NC score	0.334843 (rank : 45)	θ value	6.64225e-11 (rank : 18)
Query Neighborhood Hits	187	Target Neighborhood Hits	1788	Shared Neighborhood Hits	126
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYST4_HUMAN
NC score	0.333807 (rank : 46)	θ value	1.06045e-08 (rank : 32)
Query Neighborhood Hits	187	Target Neighborhood Hits	671	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

UHRF2_MOUSE
NC score	0.325643 (rank : 47)	θ value	4.92598e-06 (rank : 50)
Query Neighborhood Hits	187	Target Neighborhood Hits	275	Shared Neighborhood Hits	68
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

MLL3_HUMAN
NC score	0.321147 (rank : 48)	θ value	1.47974e-10 (rank : 20)
Query Neighborhood Hits	187	Target Neighborhood Hits	1644	Shared Neighborhood Hits	112
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYST3_HUMAN
NC score	0.319159 (rank : 49)	θ value	5.26297e-08 (rank : 38)
Query Neighborhood Hits	187	Target Neighborhood Hits	772	Shared Neighborhood Hits	104
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
NC score	0.319077 (rank : 50)	θ value	6.87365e-08 (rank : 39)
Query Neighborhood Hits	187	Target Neighborhood Hits	688	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

BPTF_HUMAN
NC score	0.316500 (rank : 51)	θ value	9.92553e-07 (rank : 45)
Query Neighborhood Hits	187	Target Neighborhood Hits	786	Shared Neighborhood Hits	103
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRPF1_HUMAN
NC score	0.295814 (rank : 52)	θ value	0.0252991 (rank : 82)
Query Neighborhood Hits	187	Target Neighborhood Hits	259	Shared Neighborhood Hits	87
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

BAZ2B_HUMAN
NC score	0.287554 (rank : 53)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	187	Target Neighborhood Hits	803	Shared Neighborhood Hits	98
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BRD1_HUMAN
NC score	0.283675 (rank : 54)	θ value	0.125558 (rank : 89)
Query Neighborhood Hits	187	Target Neighborhood Hits	188	Shared Neighborhood Hits	77
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

JADE3_MOUSE
NC score	0.273229 (rank : 55)	θ value	0.0148317 (rank : 74)
Query Neighborhood Hits	187	Target Neighborhood Hits	174	Shared Neighborhood Hits	82
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JADE1_HUMAN
NC score	0.269902 (rank : 56)	θ value	0.0193708 (rank : 76)
Query Neighborhood Hits	187	Target Neighborhood Hits	140	Shared Neighborhood Hits	78
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE3_HUMAN
NC score	0.269509 (rank : 57)	θ value	0.163984 (rank : 92)
Query Neighborhood Hits	187	Target Neighborhood Hits	148	Shared Neighborhood Hits	82
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE1_MOUSE
NC score	0.269430 (rank : 58)	θ value	0.0193708 (rank : 77)
Query Neighborhood Hits	187	Target Neighborhood Hits	160	Shared Neighborhood Hits	78
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

CHD5_HUMAN
NC score	0.268950 (rank : 59)	θ value	1.9326e-10 (rank : 24)
Query Neighborhood Hits	187	Target Neighborhood Hits	349	Shared Neighborhood Hits	88
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

TRI66_MOUSE
NC score	0.267817 (rank : 60)	θ value	0.00175202 (rank : 63)
Query Neighborhood Hits	187	Target Neighborhood Hits	491	Shared Neighborhood Hits	73
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CHD4_HUMAN
NC score	0.266585 (rank : 61)	θ value	1.9326e-10 (rank : 22)
Query Neighborhood Hits	187	Target Neighborhood Hits	365	Shared Neighborhood Hits	94
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.266149 (rank : 62)	θ value	1.9326e-10 (rank : 23)
Query Neighborhood Hits	187	Target Neighborhood Hits	408	Shared Neighborhood Hits	95
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

ARI4A_HUMAN
NC score	0.265969 (rank : 63)	θ value	2.21117e-06 (rank : 47)
Query Neighborhood Hits	187	Target Neighborhood Hits	434	Shared Neighborhood Hits	34
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CHD3_HUMAN
NC score	0.264701 (rank : 64)	θ value	5.62301e-10 (rank : 26)
Query Neighborhood Hits	187	Target Neighborhood Hits	397	Shared Neighborhood Hits	90
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ARID2_HUMAN
NC score	0.263486 (rank : 65)	θ value	5.44631e-05 (rank : 59)
Query Neighborhood Hits	187	Target Neighborhood Hits	302	Shared Neighborhood Hits	24
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

TRI66_HUMAN
NC score	0.259598 (rank : 66)	θ value	0.00509761 (rank : 68)
Query Neighborhood Hits	187	Target Neighborhood Hits	479	Shared Neighborhood Hits	78
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

ARI5B_MOUSE
NC score	0.256047 (rank : 67)	θ value	2.88788e-06 (rank : 48)
Query Neighborhood Hits	187	Target Neighborhood Hits	158	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

BRPF3_HUMAN
NC score	0.246996 (rank : 68)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	187	Target Neighborhood Hits	217	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

ARI5B_HUMAN
NC score	0.246927 (rank : 69)	θ value	2.44474e-05 (rank : 57)
Query Neighborhood Hits	187	Target Neighborhood Hits	328	Shared Neighborhood Hits	34
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

AF17_HUMAN
NC score	0.242990 (rank : 70)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	187	Target Neighborhood Hits	230	Shared Neighborhood Hits	60
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

TIF1A_MOUSE
NC score	0.242245 (rank : 71)	θ value	0.00390308 (rank : 65)
Query Neighborhood Hits	187	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PKCB1_HUMAN
NC score	0.241565 (rank : 72)	θ value	0.0736092 (rank : 87)
Query Neighborhood Hits	187	Target Neighborhood Hits	488	Shared Neighborhood Hits	87
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TIF1A_HUMAN
NC score	0.240675 (rank : 73)	θ value	0.00390308 (rank : 64)
Query Neighborhood Hits	187	Target Neighborhood Hits	327	Shared Neighborhood Hits	78
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

JADE2_HUMAN
NC score	0.239706 (rank : 74)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	187	Target Neighborhood Hits	199	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

TIF1B_MOUSE
NC score	0.239688 (rank : 75)	θ value	0.00390308 (rank : 67)
Query Neighborhood Hits	187	Target Neighborhood Hits	276	Shared Neighborhood Hits	66
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1B_HUMAN
NC score	0.236906 (rank : 76)	θ value	0.00390308 (rank : 66)
Query Neighborhood Hits	187	Target Neighborhood Hits	312	Shared Neighborhood Hits	69
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

ARI1B_HUMAN
NC score	0.233368 (rank : 77)	θ value	5.44631e-05 (rank : 58)
Query Neighborhood Hits	187	Target Neighborhood Hits	567	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

JADE2_MOUSE
NC score	0.226330 (rank : 78)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	187	Target Neighborhood Hits	560	Shared Neighborhood Hits	82
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

AF10_MOUSE
NC score	0.225843 (rank : 79)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	187	Target Neighborhood Hits	182	Shared Neighborhood Hits	54
SwissProt Accessions	O54826	Gene names	Mllt10, Af10
Domain Architecture
Description	Protein AF-10.

AF10_HUMAN
NC score	0.225586 (rank : 80)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	187	Target Neighborhood Hits	198	Shared Neighborhood Hits	54
SwissProt Accessions	P55197	Gene names	MLLT10, AF10
Domain Architecture
Description	Protein AF-10.

NSD1_MOUSE
NC score	0.223211 (rank : 81)	θ value	0.00175202 (rank : 62)
Query Neighborhood Hits	187	Target Neighborhood Hits	472	Shared Neighborhood Hits	83
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

TIF1G_MOUSE
NC score	0.218329 (rank : 82)	θ value	0.0193708 (rank : 81)
Query Neighborhood Hits	187	Target Neighborhood Hits	498	Shared Neighborhood Hits	73
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.217801 (rank : 83)	θ value	0.0193708 (rank : 80)
Query Neighborhood Hits	187	Target Neighborhood Hits	410	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TAF3_HUMAN
NC score	0.213972 (rank : 84)	θ value	0.00665767 (rank : 70)
Query Neighborhood Hits	187	Target Neighborhood Hits	568	Shared Neighborhood Hits	86
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ARI1A_HUMAN
NC score	0.210743 (rank : 85)	θ value	2.44474e-05 (rank : 56)
Query Neighborhood Hits	187	Target Neighborhood Hits	787	Shared Neighborhood Hits	40
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

NSD1_HUMAN
NC score	0.207955 (rank : 86)	θ value	0.0736092 (rank : 86)
Query Neighborhood Hits	187	Target Neighborhood Hits	427	Shared Neighborhood Hits	81
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

LY10_HUMAN
NC score	0.206304 (rank : 87)	θ value	0.279714 (rank : 95)
Query Neighborhood Hits	187	Target Neighborhood Hits	151	Shared Neighborhood Hits	57
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

TAF3_MOUSE
NC score	0.198944 (rank : 88)	θ value	0.279714 (rank : 97)
Query Neighborhood Hits	187	Target Neighborhood Hits	463	Shared Neighborhood Hits	83
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

MLL4_HUMAN
NC score	0.187687 (rank : 89)	θ value	3.0926 (rank : 145)
Query Neighborhood Hits	187	Target Neighborhood Hits	722	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.179502 (rank : 90)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	187	Target Neighborhood Hits	825	Shared Neighborhood Hits	87
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

SP110_HUMAN
NC score	0.167705 (rank : 91)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	187	Target Neighborhood Hits	141	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

CXCC1_HUMAN
NC score	0.163831 (rank : 92)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	187	Target Neighborhood Hits	143	Shared Neighborhood Hits	57
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
NC score	0.160871 (rank : 93)	θ value	0.365318 (rank : 99)
Query Neighborhood Hits	187	Target Neighborhood Hits	124	Shared Neighborhood Hits	57
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MTF2_HUMAN
NC score	0.158291 (rank : 94)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	187	Target Neighborhood Hits	119	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.157611 (rank : 95)	θ value	1.38821 (rank : 126)
Query Neighborhood Hits	187	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

DIDO1_HUMAN
NC score	0.138292 (rank : 96)	θ value	0.0330416 (rank : 84)
Query Neighborhood Hits	187	Target Neighborhood Hits	960	Shared Neighborhood Hits	83
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PHF20_HUMAN
NC score	0.135220 (rank : 97)	θ value	0.0113563 (rank : 72)
Query Neighborhood Hits	187	Target Neighborhood Hits	394	Shared Neighborhood Hits	57
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PHF8_HUMAN
NC score	0.135188 (rank : 98)	θ value	0.00869519 (rank : 71)
Query Neighborhood Hits	187	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UPP1, Q5H9U5, Q5VUJ4, Q7Z6D4, Q9HAH2	Gene names	PHF8, KIAA1111, ZNF422
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

K1718_HUMAN
NC score	0.134528 (rank : 99)	θ value	0.0148317 (rank : 75)
Query Neighborhood Hits	187	Target Neighborhood Hits	114	Shared Neighborhood Hits	32
SwissProt Accessions	Q6ZMT4, Q6MZL8, Q9C0E5	Gene names	KIAA1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

TCF19_HUMAN
NC score	0.133626 (rank : 100)	θ value	5.27518 (rank : 165)
Query Neighborhood Hits	187	Target Neighborhood Hits	124	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y242, Q13176, Q15967, Q5SQ89, Q5STD6, Q5STF5, Q9BUM2, Q9UBH7	Gene names	TCF19, SC1
Domain Architecture
Description	Transcription factor 19 (Transcription factor SC1).

K1718_MOUSE
NC score	0.133610 (rank : 101)	θ value	0.0193708 (rank : 78)
Query Neighborhood Hits	187	Target Neighborhood Hits	98	Shared Neighborhood Hits	33
SwissProt Accessions	Q3UWM4, Q3UWN8, Q6ZPJ5, Q8C969, Q8C9E0, Q91VX8	Gene names	Kiaa1718
Domain Architecture	No domain graphic available
Description	Protein KIAA1718.

PHF20_MOUSE
NC score	0.132365 (rank : 102)	θ value	0.00665767 (rank : 69)
Query Neighborhood Hits	187	Target Neighborhood Hits	513	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PHF8_MOUSE
NC score	0.132322 (rank : 103)	θ value	0.0193708 (rank : 79)
Query Neighborhood Hits	187	Target Neighborhood Hits	96	Shared Neighborhood Hits	35
SwissProt Accessions	Q80TJ7, Q8BLX8, Q8BLY0, Q8BZ61, Q8CG26	Gene names	Phf8, Kiaa1111
Domain Architecture	No domain graphic available
Description	PHD finger protein 8.

ZMY11_MOUSE
NC score	0.130726 (rank : 104)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	187	Target Neighborhood Hits	198	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

PHF2_HUMAN
NC score	0.129360 (rank : 105)	θ value	0.125558 (rank : 90)
Query Neighborhood Hits	187	Target Neighborhood Hits	208	Shared Neighborhood Hits	42
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PHF2_MOUSE
NC score	0.128554 (rank : 106)	θ value	0.125558 (rank : 91)
Query Neighborhood Hits	187	Target Neighborhood Hits	241	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WTU0, Q80WA8	Gene names	Phf2
Domain Architecture
Description	PHD finger protein 2 (GRC5).

ZMY11_HUMAN
NC score	0.125434 (rank : 107)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	187	Target Neighborhood Hits	201	Shared Neighborhood Hits	58
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

DPF3_MOUSE
NC score	0.114186 (rank : 108)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	187	Target Neighborhood Hits	327	Shared Neighborhood Hits	13
SwissProt Accessions	P58269	Gene names	Dpf3, Cerd4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein Dpf3 (cer-d4).

PHF1_MOUSE
NC score	0.109739 (rank : 109)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	187	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF1_HUMAN
NC score	0.108462 (rank : 110)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	187	Target Neighborhood Hits	117	Shared Neighborhood Hits	64
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF3_HUMAN
NC score	0.103631 (rank : 111)	θ value	1.38821 (rank : 128)
Query Neighborhood Hits	187	Target Neighborhood Hits	419	Shared Neighborhood Hits	54
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

ING3_HUMAN
NC score	0.103402 (rank : 112)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	187	Target Neighborhood Hits	178	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NXR8, O60394, Q6GMT3, Q7Z762, Q969G0, Q96DT4, Q9HC99, Q9P081	Gene names	ING3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

DPF3_HUMAN
NC score	0.096955 (rank : 113)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	187	Target Neighborhood Hits	13	Shared Neighborhood Hits	5
SwissProt Accessions	Q92784, Q9H7Y5	Gene names	DPF3, CERD4
Domain Architecture	No domain graphic available
Description	Zinc-finger protein DPF3 (cer-d4).

ING5_HUMAN
NC score	0.096027 (rank : 114)	θ value	3.0926 (rank : 143)
Query Neighborhood Hits	187	Target Neighborhood Hits	65	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WYH8, Q9BS30	Gene names	ING5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5 (p28ING5).

ING3_MOUSE
NC score	0.095988 (rank : 115)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	187	Target Neighborhood Hits	177	Shared Neighborhood Hits	55
SwissProt Accessions	Q8VEK6, Q99JS6, Q9ERB2	Gene names	Ing3
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 3 (p47ING3 protein).

PHF11_HUMAN
NC score	0.090735 (rank : 116)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	187	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

ING5_MOUSE
NC score	0.088833 (rank : 117)	θ value	3.0926 (rank : 144)
Query Neighborhood Hits	187	Target Neighborhood Hits	76	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D8Y8, Q3UL57, Q6P292, Q9CV64, Q9D9V8	Gene names	Ing5
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 5.

MARH4_MOUSE
NC score	0.087355 (rank : 118)	θ value	1.06291 (rank : 115)
Query Neighborhood Hits	187	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q80TE3	Gene names	March4, Kiaa1399
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 4 (Membrane-associated RING-CH protein IV) (MARCH-IV).

MARH4_HUMAN
NC score	0.079764 (rank : 119)	θ value	1.06291 (rank : 114)
Query Neighborhood Hits	187	Target Neighborhood Hits	25	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P2E8, Q86WR8	Gene names	MARCH4, KIAA1399, RNF174
Domain Architecture	No domain graphic available
Description	Membrane-associated RING finger protein 4 (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174).

CECR2_HUMAN
NC score	0.078032 (rank : 120)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	187	Target Neighborhood Hits	543	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

JHD1A_HUMAN
NC score	0.075793 (rank : 121)	θ value	2.36792 (rank : 138)
Query Neighborhood Hits	187	Target Neighborhood Hits	133	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2K7, Q49A21, Q4G0M3, Q69YY8, Q9BVH5, Q9H7H5, Q9UK66	Gene names	FBXL11, FBL7, JHDM1A, KIAA1004
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina).

JHD1A_MOUSE
NC score	0.071739 (rank : 122)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	187	Target Neighborhood Hits	134	Shared Neighborhood Hits	33
SwissProt Accessions	P59997, Q3U1M5, Q3UR56, Q3V3Q1, Q69ZT4	Gene names	Fbxl11, Jhdm1a, Kiaa1004
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1A (EC 1.14.11.-) (F-box/LRR-repeat protein 11) (F-box and leucine-rich repeat protein 11).

PHF7_MOUSE
NC score	0.070673 (rank : 123)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	187	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

ING2_MOUSE
NC score	0.070238 (rank : 124)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	187	Target Neighborhood Hits	102	Shared Neighborhood Hits	47
SwissProt Accessions	Q9ESK4, Q80VI5, Q8BGU8	Gene names	Ing2, Ing1l
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein).

PHF13_MOUSE
NC score	0.070225 (rank : 125)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	187	Target Neighborhood Hits	42	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

PHF13_HUMAN
NC score	0.068837 (rank : 126)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	187	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

ING2_HUMAN
NC score	0.068744 (rank : 127)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	187	Target Neighborhood Hits	101	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H160, O95698	Gene names	ING2, ING1L
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like protein) (ING1Lp) (p32).

MYST1_MOUSE
NC score	0.068060 (rank : 128)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	187	Target Neighborhood Hits	57	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

MYST1_HUMAN
NC score	0.067993 (rank : 129)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	187	Target Neighborhood Hits	53	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

TIP60_HUMAN
NC score	0.067836 (rank : 130)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	187	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q92993, O95624, Q13430, Q6GSE8, Q9BWK7	Gene names	HTATIP, TIP60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60) (HIV-1 Tat interactive protein) (cPLA(2)-interacting protein).

TIP60_MOUSE
NC score	0.067787 (rank : 131)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	187	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHK4, Q8CGZ3, Q8CGZ4, Q8VIH0	Gene names	Htatip, Tip60
Domain Architecture
Description	Histone acetyltransferase HTATIP (EC 2.3.1.48) (EC 2.3.1.-) (60 kDa Tat interactive protein) (Tip60).

MYST2_HUMAN
NC score	0.067511 (rank : 132)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	187	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	O95251	Gene names	MYST2, HBO1, HBOa
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

MYST2_MOUSE
NC score	0.067485 (rank : 133)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	187	Target Neighborhood Hits	87	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SVQ0, Q5SVQ1, Q5SVQ2, Q5SVQ3, Q5SVQ7, Q6PGC6, Q80Y65	Gene names	Myst2, Hbo1
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST2 (EC 2.3.1.48) (MYST protein 2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2) (Histone acetyltransferase binding to ORC1).

SMCA4_HUMAN
NC score	0.066316 (rank : 134)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	187	Target Neighborhood Hits	597	Shared Neighborhood Hits	41
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

BRD8_MOUSE
NC score	0.066252 (rank : 135)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	187	Target Neighborhood Hits	422	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

PCAF_HUMAN
NC score	0.065614 (rank : 136)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	187	Target Neighborhood Hits	68	Shared Neighborhood Hits	16
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

BRD4_MOUSE
NC score	0.065560 (rank : 137)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	187	Target Neighborhood Hits	845	Shared Neighborhood Hits	51
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SMCA2_HUMAN
NC score	0.065338 (rank : 138)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	187	Target Neighborhood Hits	503	Shared Neighborhood Hits	36
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

BRD4_HUMAN
NC score	0.064845 (rank : 139)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	187	Target Neighborhood Hits	851	Shared Neighborhood Hits	56
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD8_HUMAN
NC score	0.064679 (rank : 140)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	187	Target Neighborhood Hits	292	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

GCNL2_MOUSE
NC score	0.064655 (rank : 141)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	187	Target Neighborhood Hits	146	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

GCNL2_HUMAN
NC score	0.064375 (rank : 142)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	187	Target Neighborhood Hits	159	Shared Neighborhood Hits	23
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

CYLD_MOUSE
NC score	0.062576 (rank : 143)	θ value	0.365318 (rank : 100)
Query Neighborhood Hits	187	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TQ2, Q80VB3, Q8BXZ3, Q8BYL9, Q8CGB0	Gene names	Cyld, Cyld1, Kiaa0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

PHF22_HUMAN
NC score	0.062170 (rank : 144)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	187	Target Neighborhood Hits	121	Shared Neighborhood Hits	36
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

ING1_MOUSE
NC score	0.061692 (rank : 145)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	187	Target Neighborhood Hits	71	Shared Neighborhood Hits	45
SwissProt Accessions	Q9QXV3, Q9QUP8, Q9QXV4, Q9QZX3	Gene names	Ing1
Domain Architecture
Description	Inhibitor of growth protein 1.

PHF7_HUMAN
NC score	0.061520 (rank : 146)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	187	Target Neighborhood Hits	71	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

ING1_HUMAN
NC score	0.061321 (rank : 147)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	187	Target Neighborhood Hits	65	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UK53, O00532, O43658, Q9H007, Q9HD98, Q9HD99, Q9NS83, Q9P0U6, Q9UBC6, Q9UIJ1, Q9UIJ2, Q9UIJ3, Q9UIJ4, Q9UK52	Gene names	ING1
Domain Architecture
Description	Inhibitor of growth protein 1.

ING4_HUMAN
NC score	0.060545 (rank : 148)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	187	Target Neighborhood Hits	82	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UNL4, Q96E15, Q9H3J0	Gene names	ING4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

ING4_MOUSE
NC score	0.059984 (rank : 149)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	187	Target Neighborhood Hits	93	Shared Neighborhood Hits	49
SwissProt Accessions	Q8C0D7, Q8C1S7, Q8K3Q5, Q8K3Q6, Q8K3Q7, Q9D7F9	Gene names	Ing4
Domain Architecture	No domain graphic available
Description	Inhibitor of growth protein 4 (p29ING4).

MFAP1_HUMAN
NC score	0.059938 (rank : 150)	θ value	1.06291 (rank : 116)
Query Neighborhood Hits	187	Target Neighborhood Hits	321	Shared Neighborhood Hits	20
SwissProt Accessions	P55081	Gene names	MFAP1
Domain Architecture
Description	Microfibrillar-associated protein 1.

TXND2_HUMAN
NC score	0.059524 (rank : 151)	θ value	0.365318 (rank : 102)
Query Neighborhood Hits	187	Target Neighborhood Hits	793	Shared Neighborhood Hits	43
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

BRD2_HUMAN
NC score	0.059225 (rank : 152)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	187	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

ATRX_MOUSE
NC score	0.058699 (rank : 153)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	187	Target Neighborhood Hits	682	Shared Neighborhood Hits	48
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

SET1A_HUMAN
NC score	0.058683 (rank : 154)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	187	Target Neighborhood Hits	690	Shared Neighborhood Hits	35
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

PHF22_MOUSE
NC score	0.058520 (rank : 155)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	187	Target Neighborhood Hits	89	Shared Neighborhood Hits	36
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

BRD3_HUMAN
NC score	0.058478 (rank : 156)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	187	Target Neighborhood Hits	369	Shared Neighborhood Hits	36
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

MFAP1_MOUSE
NC score	0.057125 (rank : 157)	θ value	1.06291 (rank : 117)
Query Neighborhood Hits	187	Target Neighborhood Hits	353	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CQU1, Q3TU29, Q8CCL1, Q9CSJ5	Gene names	Mfap1
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 1.

BRD3_MOUSE
NC score	0.056841 (rank : 158)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	187	Target Neighborhood Hits	402	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

CN130_MOUSE
NC score	0.056766 (rank : 159)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	187	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BU04, Q80UT9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130 homolog.

EP300_HUMAN
NC score	0.056164 (rank : 160)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	187	Target Neighborhood Hits	821	Shared Neighborhood Hits	43
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ATRX_HUMAN
NC score	0.055891 (rank : 161)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	187	Target Neighborhood Hits	842	Shared Neighborhood Hits	59
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

TAF1_HUMAN
NC score	0.055526 (rank : 162)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	187	Target Neighborhood Hits	136	Shared Neighborhood Hits	24
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

CN130_HUMAN
NC score	0.055354 (rank : 163)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	187	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N806, Q86U21, Q86UA9, Q96BY0, Q9NVV6	Gene names	C14orf130
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf130.

CBP_MOUSE
NC score	0.055050 (rank : 164)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	187	Target Neighborhood Hits	1051	Shared Neighborhood Hits	55
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

JHD1B_HUMAN
NC score	0.054427 (rank : 165)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	187	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

CBP_HUMAN
NC score	0.054171 (rank : 166)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	187	Target Neighborhood Hits	941	Shared Neighborhood Hits	53
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CHD6_HUMAN
NC score	0.054117 (rank : 167)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	187	Target Neighborhood Hits	342	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

JHD1B_MOUSE
NC score	0.054005 (rank : 168)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	187	Target Neighborhood Hits	214	Shared Neighborhood Hits	29
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

BRDT_HUMAN
NC score	0.053667 (rank : 169)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	187	Target Neighborhood Hits	280	Shared Neighborhood Hits	28
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

CHD2_HUMAN
NC score	0.053625 (rank : 170)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	187	Target Neighborhood Hits	360	Shared Neighborhood Hits	22
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

RAI1_MOUSE
NC score	0.053558 (rank : 171)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	187	Target Neighborhood Hits	344	Shared Neighborhood Hits	28
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CYLD_HUMAN
NC score	0.053234 (rank : 172)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	187	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQC7, O94934, Q7L3N6, Q96EH0, Q9NZX9	Gene names	CYLD, CYLD1, KIAA0849
Domain Architecture	No domain graphic available
Description	Probable ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.1.2.15) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD) (Deubiquitinating enzyme CYLD).

TAF1L_HUMAN
NC score	0.052658 (rank : 173)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	187	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

BRDT_MOUSE
NC score	0.052604 (rank : 174)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	187	Target Neighborhood Hits	243	Shared Neighborhood Hits	25
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

CHD9_MOUSE
NC score	0.051268 (rank : 175)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	187	Target Neighborhood Hits	427	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD1_MOUSE
NC score	0.051136 (rank : 176)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	187	Target Neighborhood Hits	266	Shared Neighborhood Hits	19
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD9_HUMAN
NC score	0.051070 (rank : 177)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	187	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD8_HUMAN
NC score	0.050870 (rank : 178)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	187	Target Neighborhood Hits	235	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD1_HUMAN
NC score	0.050721 (rank : 179)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	187	Target Neighborhood Hits	337	Shared Neighborhood Hits	19
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

RAI1_HUMAN
NC score	0.050175 (rank : 180)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	187	Target Neighborhood Hits	360	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TCF20_HUMAN
NC score	0.049244 (rank : 181)	θ value	3.0926 (rank : 147)
Query Neighborhood Hits	187	Target Neighborhood Hits	323	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

KI67_HUMAN
NC score	0.047620 (rank : 182)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	187	Target Neighborhood Hits	581	Shared Neighborhood Hits	36
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

OGFR_MOUSE
NC score	0.039459 (rank : 183)	θ value	0.365318 (rank : 101)
Query Neighborhood Hits	187	Target Neighborhood Hits	584	Shared Neighborhood Hits	28
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

OGFR_HUMAN
NC score	0.037276 (rank : 184)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	187	Target Neighborhood Hits	1582	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BBS2_MOUSE
NC score	0.037020 (rank : 185)	θ value	2.36792 (rank : 135)
Query Neighborhood Hits	187	Target Neighborhood Hits	29	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CWF6	Gene names	Bbs2
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 2 protein homolog.

RGS3_HUMAN
NC score	0.035580 (rank : 186)	θ value	0.0113563 (rank : 73)
Query Neighborhood Hits	187	Target Neighborhood Hits	1375	Shared Neighborhood Hits	49
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

PRIMA_HUMAN
NC score	0.032626 (rank : 187)	θ value	1.06291 (rank : 119)
Query Neighborhood Hits	187	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q86XR5, Q86XR6	Gene names	PRIMA1
Domain Architecture	No domain graphic available
Description	Proline-rich membrane anchor 1 precursor (PRiMA).

BBS2_HUMAN
NC score	0.032352 (rank : 188)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	187	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXC9, Q96CM0, Q96SN9	Gene names	BBS2
Domain Architecture	No domain graphic available
Description	Bardet-Biedl syndrome 2 protein.

BPAEA_HUMAN
NC score	0.032175 (rank : 189)	θ value	0.279714 (rank : 94)
Query Neighborhood Hits	187	Target Neighborhood Hits	1369	Shared Neighborhood Hits	42
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MACF4_HUMAN
NC score	0.031230 (rank : 190)	θ value	0.813845 (rank : 110)
Query Neighborhood Hits	187	Target Neighborhood Hits	1321	Shared Neighborhood Hits	42
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

SYNE2_HUMAN
NC score	0.028588 (rank : 191)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	187	Target Neighborhood Hits	1323	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

BPA1_MOUSE
NC score	0.028157 (rank : 192)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	187	Target Neighborhood Hits	1477	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TRIPB_HUMAN
NC score	0.027704 (rank : 193)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	187	Target Neighborhood Hits	1587	Shared Neighborhood Hits	61
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

MACF1_HUMAN
NC score	0.027675 (rank : 194)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	187	Target Neighborhood Hits	1341	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

ATX7_HUMAN
NC score	0.027430 (rank : 195)	θ value	2.36792 (rank : 134)
Query Neighborhood Hits	187	Target Neighborhood Hits	351	Shared Neighborhood Hits	21
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

BEGIN_HUMAN
NC score	0.026034 (rank : 196)	θ value	0.47712 (rank : 103)
Query Neighborhood Hits	187	Target Neighborhood Hits	454	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BUH8, Q9NPU3, Q9P282	Gene names	BEGAIN, KIAA1446
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

PLEC1_HUMAN
NC score	0.025924 (rank : 197)	θ value	0.279714 (rank : 96)
Query Neighborhood Hits	187	Target Neighborhood Hits	1326	Shared Neighborhood Hits	45
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SPTA1_HUMAN
NC score	0.025647 (rank : 198)	θ value	0.163984 (rank : 93)
Query Neighborhood Hits	187	Target Neighborhood Hits	748	Shared Neighborhood Hits	21
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

PRIMA_MOUSE
NC score	0.025210 (rank : 199)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	187	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q810F0, Q8VHC4	Gene names	Prima1
Domain Architecture	No domain graphic available
Description	Proline-rich membrane anchor 1 precursor (PRiMA).

U171_HUMAN
NC score	0.024853 (rank : 200)	θ value	6.88961 (rank : 178)
Query Neighborhood Hits	187	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q12980, Q4TT56, Q92469	Gene names	CGTHBA, C16orf35
Domain Architecture
Description	CGTHBA protein (-14 gene protein).

PCNT_HUMAN
NC score	0.024082 (rank : 201)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	187	Target Neighborhood Hits	1551	Shared Neighborhood Hits	50
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CROCC_MOUSE
NC score	0.023506 (rank : 202)	θ value	0.0252991 (rank : 83)
Query Neighborhood Hits	187	Target Neighborhood Hits	1460	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

BEGIN_MOUSE
NC score	0.022386 (rank : 203)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	187	Target Neighborhood Hits	383	Shared Neighborhood Hits	14
SwissProt Accessions	Q68EF6	Gene names	Begain
Domain Architecture	No domain graphic available
Description	Brain-enriched guanylate kinase-associated protein.

CE290_HUMAN
NC score	0.022049 (rank : 204)	θ value	2.36792 (rank : 136)
Query Neighborhood Hits	187	Target Neighborhood Hits	1553	Shared Neighborhood Hits	54
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TMC1_MOUSE
NC score	0.021299 (rank : 205)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	187	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4P5, Q9D435	Gene names	Tmc1, Bth, dn
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 1 (Beethoven protein) (Deafness protein).

IF16_HUMAN
NC score	0.019675 (rank : 206)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	187	Target Neighborhood Hits	182	Shared Neighborhood Hits	11
SwissProt Accessions	Q16666, Q9UH78	Gene names	IFI16, IFNGIP1
Domain Architecture
Description	Gamma-interferon-inducible protein Ifi-16 (Interferon-inducible myeloid differentiation transcriptional activator) (IFI 16).

AKAP9_HUMAN
NC score	0.019574 (rank : 207)	θ value	3.0926 (rank : 141)
Query Neighborhood Hits	187	Target Neighborhood Hits	1710	Shared Neighborhood Hits	53
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

MY18A_HUMAN
NC score	0.018652 (rank : 208)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	187	Target Neighborhood Hits	1929	Shared Neighborhood Hits	60
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

KTN1_MOUSE
NC score	0.018168 (rank : 209)	θ value	5.27518 (rank : 163)
Query Neighborhood Hits	187	Target Neighborhood Hits	1324	Shared Neighborhood Hits	53
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LAMC2_HUMAN
NC score	0.017518 (rank : 210)	θ value	0.0736092 (rank : 85)
Query Neighborhood Hits	187	Target Neighborhood Hits	715	Shared Neighborhood Hits	26
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SPTA2_HUMAN
NC score	0.017148 (rank : 211)	θ value	5.27518 (rank : 164)
Query Neighborhood Hits	187	Target Neighborhood Hits	888	Shared Neighborhood Hits	27
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

SEBP2_HUMAN
NC score	0.016730 (rank : 212)	θ value	3.0926 (rank : 146)
Query Neighborhood Hits	187	Target Neighborhood Hits	88	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T21, Q8IYC0	Gene names	SECISBP2, SBP2
Domain Architecture
Description	SECIS-binding protein 2 (Selenocysteine insertion sequence-binding protein 2).

DDX21_HUMAN
NC score	0.016654 (rank : 213)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	187	Target Neighborhood Hits	308	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

LAMB1_HUMAN
NC score	0.016640 (rank : 214)	θ value	0.0961366 (rank : 88)
Query Neighborhood Hits	187	Target Neighborhood Hits	1018	Shared Neighborhood Hits	28
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SPTB2_HUMAN
NC score	0.016636 (rank : 215)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	187	Target Neighborhood Hits	748	Shared Neighborhood Hits	26
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

MUC1_HUMAN
NC score	0.015593 (rank : 216)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	187	Target Neighborhood Hits	975	Shared Neighborhood Hits	29
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

HOOK2_HUMAN
NC score	0.015537 (rank : 217)	θ value	0.47712 (rank : 104)
Query Neighborhood Hits	187	Target Neighborhood Hits	714	Shared Neighborhood Hits	29
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

I11RB_MOUSE
NC score	0.014922 (rank : 218)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	187	Target Neighborhood Hits	101	Shared Neighborhood Hits	6
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

STX1A_MOUSE
NC score	0.014276 (rank : 219)	θ value	6.88961 (rank : 173)
Query Neighborhood Hits	187	Target Neighborhood Hits	261	Shared Neighborhood Hits	18
SwissProt Accessions	O35526	Gene names	Stx1a
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

IP6K3_MOUSE
NC score	0.014208 (rank : 220)	θ value	2.36792 (rank : 137)
Query Neighborhood Hits	187	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWD2	Gene names	Ihpk3, Ip6k3
Domain Architecture	No domain graphic available
Description	Inositol hexaphosphate kinase 3 (EC 2.7.4.21) (InsP6 kinase 3) (Inositol hexakisphosphate kinase 3).

OXRP_HUMAN
NC score	0.014147 (rank : 221)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	187	Target Neighborhood Hits	544	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

CROCC_HUMAN
NC score	0.013915 (rank : 222)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	187	Target Neighborhood Hits	1409	Shared Neighborhood Hits	41
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

STX1A_HUMAN
NC score	0.013497 (rank : 223)	θ value	6.88961 (rank : 172)
Query Neighborhood Hits	187	Target Neighborhood Hits	266	Shared Neighborhood Hits	16
SwissProt Accessions	Q16623, O15447, O15448, Q12936, Q9BPZ6	Gene names	STX1A, STX1
Domain Architecture
Description	Syntaxin-1A (Neuron-specific antigen HPC-1).

MSLN_HUMAN
NC score	0.012671 (rank : 224)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	187	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q13421, Q14859, Q4VQD5, Q96GR6, Q96KJ5, Q9BR17, Q9BTR2, Q9UK57	Gene names	MSLN, MPF
Domain Architecture
Description	Mesothelin precursor (Pre-pro-megakaryocyte potentiating factor) (CAK1 antigen) [Contains: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form].

RIMB1_HUMAN
NC score	0.012478 (rank : 225)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	187	Target Neighborhood Hits	1479	Shared Neighborhood Hits	46
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZN385_HUMAN
NC score	0.012177 (rank : 226)	θ value	1.38821 (rank : 129)
Query Neighborhood Hits	187	Target Neighborhood Hits	614	Shared Neighborhood Hits	13
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

CTDP1_MOUSE
NC score	0.012050 (rank : 227)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	187	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TSG2, Q7TSS7, Q9D4S8	Gene names	Ctdp1, Fcp1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

I11RA_MOUSE
NC score	0.011139 (rank : 228)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	187	Target Neighborhood Hits	95	Shared Neighborhood Hits	6
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

SYFB_HUMAN
NC score	0.011024 (rank : 229)	θ value	6.88961 (rank : 174)
Query Neighborhood Hits	187	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSD9, O95708, Q9NZZ6	Gene names	FARSLB, FARSB, FRSB
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

IF4G1_MOUSE
NC score	0.010748 (rank : 230)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	187	Target Neighborhood Hits	534	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

TNR22_MOUSE
NC score	0.010747 (rank : 231)	θ value	6.88961 (rank : 177)
Query Neighborhood Hits	187	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER62, Q8VHB9, Q9CZA4	Gene names	Tnfrsf22, Dctrailr2, Tnfrh2, Tnfrsf1al2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2) (TNF receptor family member SOBa) (Decoy TRAIL receptor 2) (TNF receptor homolog 2).

B4GT1_HUMAN
NC score	0.010434 (rank : 232)	θ value	3.0926 (rank : 142)
Query Neighborhood Hits	187	Target Neighborhood Hits	168	Shared Neighborhood Hits	7
SwissProt Accessions	P15291, Q12909, Q12910, Q12911, Q14456, Q14509, Q14523	Gene names	B4GALT1, GGTB2
Domain Architecture
Description	Beta-1,4-galactosyltransferase 1 (EC 2.4.1.-) (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (UDP-galactose:beta-N-acetylglucosamine beta- 1,4-galactosyltransferase 1) (UDP-Gal:beta-GlcNAc beta-1,4- galactosyltransferase 1) [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthetase); Beta-N-acetylglucosaminylglycopeptide beta-1,4- galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl- glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)].

SYFB_MOUSE
NC score	0.010125 (rank : 233)	θ value	8.99809 (rank : 186)
Query Neighborhood Hits	187	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WUA2	Gene names	Farslb, Farsb, Farsl, Frsb
Domain Architecture
Description	Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) (Phenylalanine-- tRNA ligase beta chain) (PheRS).

ZO1_HUMAN
NC score	0.009412 (rank : 234)	θ value	4.03905 (rank : 157)
Query Neighborhood Hits	187	Target Neighborhood Hits	474	Shared Neighborhood Hits	16
SwissProt Accessions	Q07157, Q4ZGJ6	Gene names	TJP1, ZO1
Domain Architecture
Description	Tight junction protein ZO-1 (Zonula occludens 1 protein) (Zona occludens 1 protein) (Tight junction protein 1).

ELL_HUMAN
NC score	0.009260 (rank : 235)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	187	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

STXB4_MOUSE
NC score	0.008318 (rank : 236)	θ value	4.03905 (rank : 155)
Query Neighborhood Hits	187	Target Neighborhood Hits	629	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WV89, Q5SUA6, Q5SUA8, Q5SUA9, Q8CFL1	Gene names	Stxbp4
Domain Architecture	No domain graphic available
Description	Syntaxin-binding protein 4 (Syntaxin 4-interacting protein) (Synip).

K0427_MOUSE
NC score	0.007733 (rank : 237)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	187	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

SYTL1_HUMAN
NC score	0.007727 (rank : 238)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	187	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYJ3, Q96BB6, Q96GU6, Q96S89, Q96SI0	Gene names	SYTL1, SLP1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) (SB146).

DDX49_HUMAN
NC score	0.005417 (rank : 239)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	187	Target Neighborhood Hits	223	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6V7, Q53FJ1	Gene names	DDX49
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX49 (EC 3.6.1.-) (DEAD box protein 49).

TLE4_MOUSE
NC score	0.002790 (rank : 240)	θ value	6.88961 (rank : 176)
Query Neighborhood Hits	187	Target Neighborhood Hits	482	Shared Neighborhood Hits	7
SwissProt Accessions	Q62441, Q9JKQ9	Gene names	Tle4, Grg4
Domain Architecture
Description	Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg- 4).

TLE4_HUMAN
NC score	0.002775 (rank : 241)	θ value	6.88961 (rank : 175)
Query Neighborhood Hits	187	Target Neighborhood Hits	477	Shared Neighborhood Hits	7
SwissProt Accessions	Q04727, Q5T1Y2, Q9BZ07, Q9BZ08, Q9BZ09, Q9NSL3, Q9ULF9	Gene names	TLE4, KIAA1261
Domain Architecture
Description	Transducin-like enhancer protein 4.

CXA4_MOUSE
NC score	0.002609 (rank : 242)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	187	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P28235	Gene names	Gja4, Cxn-37
Domain Architecture
Description	Gap junction alpha-4 protein (Connexin-37) (Cx37).

FINC_MOUSE
NC score	0.000965 (rank : 243)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	187	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

MYPT2_HUMAN
NC score	-0.000307 (rank : 244)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	187	Target Neighborhood Hits	707	Shared Neighborhood Hits	17
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

PAK3_MOUSE
NC score	-0.001112 (rank : 245)	θ value	1.06291 (rank : 118)
Query Neighborhood Hits	187	Target Neighborhood Hits	874	Shared Neighborhood Hits	7
SwissProt Accessions	Q61036, O88645, Q8K1R5, Q8K1R6	Gene names	Pak3, Pak-3, Pakb, Stk4
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (CDC42/RAC effector kinase PAK-B).

AATK_HUMAN
NC score	-0.001749 (rank : 246)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	187	Target Neighborhood Hits	1243	Shared Neighborhood Hits	20
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

PAK3_HUMAN
NC score	-0.001820 (rank : 247)	θ value	1.38821 (rank : 127)
Query Neighborhood Hits	187	Target Neighborhood Hits	887	Shared Neighborhood Hits	7
SwissProt Accessions	O75914, Q5JWX1, Q5JWX2, Q7Z2D6, Q7Z2E4, Q7Z3Z8, Q8WWK5, Q8WX23, Q9P0J8	Gene names	PAK3, OPHN3
Domain Architecture
Description	Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (p21-activated kinase 3) (PAK-3) (Beta-PAK) (Oligophrenin-3).

OBSCN_HUMAN
NC score	-0.002769 (rank : 248)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	187	Target Neighborhood Hits	1931	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

ZN438_HUMAN
NC score	-0.003598 (rank : 249)	θ value	8.99809 (rank : 187)
Query Neighborhood Hits	187	Target Neighborhood Hits	906	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z4V0, Q5T426, Q658Q4, Q6ZN65	Gene names	ZNF438
Domain Architecture	No domain graphic available
Description	Zinc finger protein 438.

ZN688_HUMAN
NC score	-0.004343 (rank : 250)	θ value	4.03905 (rank : 156)
Query Neighborhood Hits	187	Target Neighborhood Hits	873	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WV14, O75701, Q8IW91, Q96MN0	Gene names	ZNF688
Domain Architecture	No domain graphic available
Description	Zinc finger protein 688.

PRDM1_MOUSE
NC score	-0.004741 (rank : 251)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	187	Target Neighborhood Hits	766	Shared Neighborhood Hits	6
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).