Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : PHF22_HUMAN

For an explanation of this page, click here

PHF22_HUMAN
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PHF22_HUMAN
θ value	1.41594e-162 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	121	Target Neighborhood Hits	121	Shared Neighborhood Hits	121
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	6.17048e-150 (rank : 2)	NC score	0.962905 (rank : 2)
Query Neighborhood Hits	121	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF1_HUMAN
θ value	2.21117e-06 (rank : 3)	NC score	0.378429 (rank : 4)
Query Neighborhood Hits	121	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	2.21117e-06 (rank : 4)	NC score	0.378665 (rank : 3)
Query Neighborhood Hits	121	Target Neighborhood Hits	116	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PF21A_HUMAN
θ value	0.000602161 (rank : 5)	NC score	0.260949 (rank : 8)
Query Neighborhood Hits	121	Target Neighborhood Hits	303	Shared Neighborhood Hits	47
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	0.000786445 (rank : 6)	NC score	0.266269 (rank : 7)
Query Neighborhood Hits	121	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

HRX_HUMAN
θ value	0.00102713 (rank : 7)	NC score	0.189311 (rank : 17)
Query Neighborhood Hits	121	Target Neighborhood Hits	825	Shared Neighborhood Hits	58
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MTF2_HUMAN
θ value	0.00134147 (rank : 8)	NC score	0.314362 (rank : 5)
Query Neighborhood Hits	121	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
θ value	0.00134147 (rank : 9)	NC score	0.313142 (rank : 6)
Query Neighborhood Hits	121	Target Neighborhood Hits	126	Shared Neighborhood Hits	40
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

TIF1A_MOUSE
θ value	0.00298849 (rank : 10)	NC score	0.207743 (rank : 11)
Query Neighborhood Hits	121	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

SP110_HUMAN
θ value	0.00390308 (rank : 11)	NC score	0.232956 (rank : 9)
Query Neighborhood Hits	121	Target Neighborhood Hits	141	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TIF1A_HUMAN
θ value	0.00869519 (rank : 12)	NC score	0.203754 (rank : 13)
Query Neighborhood Hits	121	Target Neighborhood Hits	327	Shared Neighborhood Hits	40
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

MAP4_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.087195 (rank : 66)
Query Neighborhood Hits	121	Target Neighborhood Hits	428	Shared Neighborhood Hits	26
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ARI4A_HUMAN
θ value	0.0252991 (rank : 14)	NC score	0.092830 (rank : 59)
Query Neighborhood Hits	121	Target Neighborhood Hits	434	Shared Neighborhood Hits	15
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CIR_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.102715 (rank : 44)
Query Neighborhood Hits	121	Target Neighborhood Hits	255	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

TF3B_MOUSE
θ value	0.0330416 (rank : 16)	NC score	0.117535 (rank : 34)
Query Neighborhood Hits	121	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFK2	Gene names	Brf1
Domain Architecture	No domain graphic available
Description	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1).

TIF1B_HUMAN
θ value	0.0330416 (rank : 17)	NC score	0.202288 (rank : 14)
Query Neighborhood Hits	121	Target Neighborhood Hits	312	Shared Neighborhood Hits	38
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	0.0563607 (rank : 18)	NC score	0.204985 (rank : 12)
Query Neighborhood Hits	121	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

CCDC5_HUMAN
θ value	0.0736092 (rank : 19)	NC score	0.104683 (rank : 43)
Query Neighborhood Hits	121	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

DOT1L_HUMAN
θ value	0.0961366 (rank : 20)	NC score	0.076009 (rank : 75)
Query Neighborhood Hits	121	Target Neighborhood Hits	660	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

NFH_MOUSE
θ value	0.0961366 (rank : 21)	NC score	0.038881 (rank : 114)
Query Neighborhood Hits	121	Target Neighborhood Hits	2247	Shared Neighborhood Hits	60
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

DCBD2_HUMAN
θ value	0.125558 (rank : 22)	NC score	0.031842 (rank : 126)
Query Neighborhood Hits	121	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

LY10_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.214629 (rank : 10)
Query Neighborhood Hits	121	Target Neighborhood Hits	151	Shared Neighborhood Hits	37
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MLL3_MOUSE
θ value	0.125558 (rank : 24)	NC score	0.152799 (rank : 24)
Query Neighborhood Hits	121	Target Neighborhood Hits	1399	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

RAI1_HUMAN
θ value	0.125558 (rank : 25)	NC score	0.109093 (rank : 41)
Query Neighborhood Hits	121	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PHF12_HUMAN
θ value	0.163984 (rank : 26)	NC score	0.195931 (rank : 16)
Query Neighborhood Hits	121	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.198294 (rank : 15)
Query Neighborhood Hits	121	Target Neighborhood Hits	172	Shared Neighborhood Hits	42
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

EEA1_MOUSE
θ value	0.21417 (rank : 28)	NC score	0.017790 (rank : 151)
Query Neighborhood Hits	121	Target Neighborhood Hits	1637	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MLL3_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.144191 (rank : 28)
Query Neighborhood Hits	121	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CCDC5_MOUSE
θ value	0.279714 (rank : 30)	NC score	0.100022 (rank : 48)
Query Neighborhood Hits	121	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHX1, Q3UIH2, Q8R1M1	Gene names	Ccdc5
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5.

CCNA2_HUMAN
θ value	0.279714 (rank : 31)	NC score	0.043710 (rank : 108)
Query Neighborhood Hits	121	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P20248	Gene names	CCNA2, CCN1, CCNA
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

DPF1_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.141164 (rank : 29)
Query Neighborhood Hits	121	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TIF1G_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.179682 (rank : 20)
Query Neighborhood Hits	121	Target Neighborhood Hits	410	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.365318 (rank : 34)	NC score	0.180542 (rank : 19)
Query Neighborhood Hits	121	Target Neighborhood Hits	498	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

MLL4_HUMAN
θ value	0.47712 (rank : 35)	NC score	0.152278 (rank : 26)
Query Neighborhood Hits	121	Target Neighborhood Hits	722	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

PHF13_HUMAN
θ value	0.47712 (rank : 36)	NC score	0.115009 (rank : 37)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

PHF13_MOUSE
θ value	0.47712 (rank : 37)	NC score	0.115098 (rank : 36)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

RPGR_MOUSE
θ value	0.47712 (rank : 38)	NC score	0.051029 (rank : 101)
Query Neighborhood Hits	121	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

HTF4_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.030894 (rank : 128)
Query Neighborhood Hits	121	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

MUC1_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.068624 (rank : 86)
Query Neighborhood Hits	121	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

MYST3_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.102005 (rank : 45)
Query Neighborhood Hits	121	Target Neighborhood Hits	772	Shared Neighborhood Hits	55
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

TRI66_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.187984 (rank : 18)
Query Neighborhood Hits	121	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SAPS1_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.041231 (rank : 110)
Query Neighborhood Hits	121	Target Neighborhood Hits	704	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CYLC1_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.036881 (rank : 118)
Query Neighborhood Hits	121	Target Neighborhood Hits	408	Shared Neighborhood Hits	17
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

DDX21_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.020192 (rank : 147)
Query Neighborhood Hits	121	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DPF1_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.137424 (rank : 31)
Query Neighborhood Hits	121	Target Neighborhood Hits	136	Shared Neighborhood Hits	42
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MAST2_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.005952 (rank : 163)
Query Neighborhood Hits	121	Target Neighborhood Hits	1110	Shared Neighborhood Hits	19
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

PF21B_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.176286 (rank : 22)
Query Neighborhood Hits	121	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

UHRF1_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.108031 (rank : 42)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CA103_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.054755 (rank : 95)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

MLL2_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.137812 (rank : 30)
Query Neighborhood Hits	121	Target Neighborhood Hits	1788	Shared Neighborhood Hits	71
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FANCM_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.031840 (rank : 127)
Query Neighborhood Hits	121	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

RGP2_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.028558 (rank : 133)
Query Neighborhood Hits	121	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

SAFB2_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.025715 (rank : 136)
Query Neighborhood Hits	121	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

SNPC1_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.039249 (rank : 113)
Query Neighborhood Hits	121	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q16533	Gene names	SNAPC1, SNAP43
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE- binding factor subunit gamma) (PTF subunit gamma).

TAF3_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.090581 (rank : 63)
Query Neighborhood Hits	121	Target Neighborhood Hits	463	Shared Neighborhood Hits	42
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TRI66_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.177715 (rank : 21)
Query Neighborhood Hits	121	Target Neighborhood Hits	479	Shared Neighborhood Hits	49
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

BAZ2B_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.109691 (rank : 40)
Query Neighborhood Hits	121	Target Neighborhood Hits	803	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

COE3_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.029032 (rank : 131)
Query Neighborhood Hits	121	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.029233 (rank : 130)
Query Neighborhood Hits	121	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

CSF1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.037247 (rank : 117)
Query Neighborhood Hits	121	Target Neighborhood Hits	258	Shared Neighborhood Hits	12
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

MINT_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.047860 (rank : 103)
Query Neighborhood Hits	121	Target Neighborhood Hits	1291	Shared Neighborhood Hits	51
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

PHLB2_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.024393 (rank : 139)
Query Neighborhood Hits	121	Target Neighborhood Hits	964	Shared Neighborhood Hits	30
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PRGR_MOUSE
θ value	2.36792 (rank : 64)	NC score	0.014449 (rank : 157)
Query Neighborhood Hits	121	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

RIMS1_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.022579 (rank : 142)
Query Neighborhood Hits	121	Target Neighborhood Hits	437	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

CKAP5_HUMAN
θ value	3.0926 (rank : 66)	NC score	0.038712 (rank : 115)
Query Neighborhood Hits	121	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

LRRF1_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.025640 (rank : 137)
Query Neighborhood Hits	121	Target Neighborhood Hits	625	Shared Neighborhood Hits	12
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

MUC5B_HUMAN
θ value	3.0926 (rank : 68)	NC score	0.030207 (rank : 129)
Query Neighborhood Hits	121	Target Neighborhood Hits	1020	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

TCAL3_MOUSE
θ value	3.0926 (rank : 69)	NC score	0.028759 (rank : 132)
Query Neighborhood Hits	121	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

UBP31_HUMAN
θ value	3.0926 (rank : 70)	NC score	0.020832 (rank : 144)
Query Neighborhood Hits	121	Target Neighborhood Hits	293	Shared Neighborhood Hits	14
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

WAPL_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.044844 (rank : 106)
Query Neighborhood Hits	121	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

ZAN_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.027370 (rank : 134)
Query Neighborhood Hits	121	Target Neighborhood Hits	679	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

DDX21_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.024482 (rank : 138)
Query Neighborhood Hits	121	Target Neighborhood Hits	350	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

DPOD3_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.035524 (rank : 120)
Query Neighborhood Hits	121	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

ENL_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.038332 (rank : 116)
Query Neighborhood Hits	121	Target Neighborhood Hits	305	Shared Neighborhood Hits	19
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

IF3X_HUMAN
θ value	4.03905 (rank : 76)	NC score	0.051810 (rank : 99)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

MORC2_HUMAN
θ value	4.03905 (rank : 77)	NC score	0.018789 (rank : 150)
Query Neighborhood Hits	121	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

RP3A_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.020066 (rank : 148)
Query Neighborhood Hits	121	Target Neighborhood Hits	510	Shared Neighborhood Hits	27
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

TCAL1_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.033239 (rank : 125)
Query Neighborhood Hits	121	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q921P9	Gene names	Tceal1
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Transcription elongation factor S-II protein-like 1).

UBQL3_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.016669 (rank : 153)
Query Neighborhood Hits	121	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

WAPL_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.040383 (rank : 111)
Query Neighborhood Hits	121	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

ZN583_MOUSE
θ value	4.03905 (rank : 82)	NC score	-0.000005 (rank : 167)
Query Neighborhood Hits	121	Target Neighborhood Hits	774	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.

AFF1_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.033315 (rank : 124)
Query Neighborhood Hits	121	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ANK2_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.020759 (rank : 145)
Query Neighborhood Hits	121	Target Neighborhood Hits	1615	Shared Neighborhood Hits	51
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

BCAS1_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.034781 (rank : 121)
Query Neighborhood Hits	121	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

CJ108_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.043090 (rank : 109)
Query Neighborhood Hits	121	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

COHA1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.016706 (rank : 152)
Query Neighborhood Hits	121	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

HERC2_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.014900 (rank : 155)
Query Neighborhood Hits	121	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

JAD1A_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.081352 (rank : 70)
Query Neighborhood Hits	121	Target Neighborhood Hits	328	Shared Neighborhood Hits	49
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

JADE2_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.100156 (rank : 47)
Query Neighborhood Hits	121	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

JADE2_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.098408 (rank : 51)
Query Neighborhood Hits	121	Target Neighborhood Hits	560	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

KPCI_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.002700 (rank : 165)
Query Neighborhood Hits	121	Target Neighborhood Hits	885	Shared Neighborhood Hits	7
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

KPCI_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.002697 (rank : 166)
Query Neighborhood Hits	121	Target Neighborhood Hits	888	Shared Neighborhood Hits	7
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

PODXL_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.046460 (rank : 105)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

S18L1_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.020623 (rank : 146)
Query Neighborhood Hits	121	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O75177, Q5JXJ3, Q8NE69, Q9BR55, Q9H4K6	Gene names	SS18L1, KIAA0693
Domain Architecture
Description	SS18-like protein 1 (SYT homolog 1).

TAF3_HUMAN
θ value	5.27518 (rank : 96)	NC score	0.079685 (rank : 71)
Query Neighborhood Hits	121	Target Neighborhood Hits	568	Shared Neighborhood Hits	40
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BASP_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.034634 (rank : 122)
Query Neighborhood Hits	121	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BPTF_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.126209 (rank : 32)
Query Neighborhood Hits	121	Target Neighborhood Hits	786	Shared Neighborhood Hits	62
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CEP70_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.019046 (rank : 149)
Query Neighborhood Hits	121	Target Neighborhood Hits	432	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

CO002_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.047529 (rank : 104)
Query Neighborhood Hits	121	Target Neighborhood Hits	387	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

ECT2_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.009070 (rank : 160)
Query Neighborhood Hits	121	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

ELF4_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.010411 (rank : 158)
Query Neighborhood Hits	121	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

FXL19_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.043759 (rank : 107)
Query Neighborhood Hits	121	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

REQU_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.123660 (rank : 33)
Query Neighborhood Hits	121	Target Neighborhood Hits	523	Shared Neighborhood Hits	43
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SQSTM_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.024241 (rank : 140)
Query Neighborhood Hits	121	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

VGFR1_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.002994 (rank : 164)
Query Neighborhood Hits	121	Target Neighborhood Hits	1109	Shared Neighborhood Hits	7
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

WNK2_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.007992 (rank : 161)
Query Neighborhood Hits	121	Target Neighborhood Hits	1407	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

BAZ2A_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.115009 (rank : 38)
Query Neighborhood Hits	121	Target Neighborhood Hits	780	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BRPF1_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.093281 (rank : 58)
Query Neighborhood Hits	121	Target Neighborhood Hits	259	Shared Neighborhood Hits	43
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

HCFC1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.015936 (rank : 154)
Query Neighborhood Hits	121	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

JADE3_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.094656 (rank : 55)
Query Neighborhood Hits	121	Target Neighborhood Hits	148	Shared Neighborhood Hits	41
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

JADE3_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.095455 (rank : 52)
Query Neighborhood Hits	121	Target Neighborhood Hits	174	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

JHD1B_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.034227 (rank : 123)
Query Neighborhood Hits	121	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.036362 (rank : 119)
Query Neighborhood Hits	121	Target Neighborhood Hits	214	Shared Neighborhood Hits	21
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

LIMD1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.014511 (rank : 156)
Query Neighborhood Hits	121	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

MAP1A_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.027231 (rank : 135)
Query Neighborhood Hits	121	Target Neighborhood Hits	1626	Shared Neighborhood Hits	38
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

NFH_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.022203 (rank : 143)
Query Neighborhood Hits	121	Target Neighborhood Hits	1242	Shared Neighborhood Hits	30
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

RPGF2_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.010109 (rank : 159)
Query Neighborhood Hits	121	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

SIN3B_MOUSE
θ value	8.99809 (rank : 119)	NC score	0.023888 (rank : 141)
Query Neighborhood Hits	121	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

SRRM1_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.039494 (rank : 112)
Query Neighborhood Hits	121	Target Neighborhood Hits	966	Shared Neighborhood Hits	41
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TITIN_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.007105 (rank : 162)
Query Neighborhood Hits	121	Target Neighborhood Hits	2923	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AIRE_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.154160 (rank : 23)
Query Neighborhood Hits	121	Target Neighborhood Hits	144	Shared Neighborhood Hits	39
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.144372 (rank : 27)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.099581 (rank : 49)
Query Neighborhood Hits	121	Target Neighborhood Hits	693	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.089972 (rank : 64)
Query Neighborhood Hits	121	Target Neighborhood Hits	701	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.090896 (rank : 62)
Query Neighborhood Hits	121	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.111055 (rank : 39)
Query Neighborhood Hits	121	Target Neighborhood Hits	744	Shared Neighborhood Hits	59
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BRD1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.079390 (rank : 72)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.074143 (rank : 76)
Query Neighborhood Hits	121	Target Neighborhood Hits	217	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CHD3_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.069926 (rank : 84)
Query Neighborhood Hits	121	Target Neighborhood Hits	397	Shared Neighborhood Hits	46
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.072491 (rank : 80)
Query Neighborhood Hits	121	Target Neighborhood Hits	365	Shared Neighborhood Hits	45
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.072200 (rank : 81)
Query Neighborhood Hits	121	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.073269 (rank : 78)
Query Neighborhood Hits	121	Target Neighborhood Hits	349	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CSR2B_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.063491 (rank : 89)
Query Neighborhood Hits	121	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8E8, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5	Gene names	CSRP2BP
Domain Architecture
Description	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (CRP2BP) (CRP2-binding partner).

CXCC1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.051559 (rank : 100)
Query Neighborhood Hits	121	Target Neighborhood Hits	143	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

CXCC1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.050743 (rank : 102)
Query Neighborhood Hits	121	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

JAD1C_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.062170 (rank : 91)
Query Neighborhood Hits	121	Target Neighborhood Hits	187	Shared Neighborhood Hits	36
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

JAD1C_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.062593 (rank : 90)
Query Neighborhood Hits	121	Target Neighborhood Hits	164	Shared Neighborhood Hits	36
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1D_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.070702 (rank : 83)
Query Neighborhood Hits	121	Target Neighborhood Hits	147	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JAD1D_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.065805 (rank : 87)
Query Neighborhood Hits	121	Target Neighborhood Hits	228	Shared Neighborhood Hits	42
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

JADE1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.086419 (rank : 67)
Query Neighborhood Hits	121	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.086382 (rank : 68)
Query Neighborhood Hits	121	Target Neighborhood Hits	160	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

MYST3_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.089719 (rank : 65)
Query Neighborhood Hits	121	Target Neighborhood Hits	688	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.091049 (rank : 61)
Query Neighborhood Hits	121	Target Neighborhood Hits	671	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.093615 (rank : 57)
Query Neighborhood Hits	121	Target Neighborhood Hits	416	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

NSD1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.091476 (rank : 60)
Query Neighborhood Hits	121	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.095270 (rank : 53)
Query Neighborhood Hits	121	Target Neighborhood Hits	472	Shared Neighborhood Hits	51
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PF21B_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.152651 (rank : 25)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.095001 (rank : 54)
Query Neighborhood Hits	121	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.094272 (rank : 56)
Query Neighborhood Hits	121	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.052575 (rank : 97)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF14_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.078575 (rank : 73)
Query Neighborhood Hits	121	Target Neighborhood Hits	447	Shared Neighborhood Hits	52
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.076792 (rank : 74)
Query Neighborhood Hits	121	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PKCB1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.098633 (rank : 50)
Query Neighborhood Hits	121	Target Neighborhood Hits	488	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PML_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.054316 (rank : 96)
Query Neighborhood Hits	121	Target Neighborhood Hits	248	Shared Neighborhood Hits	15
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PML_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.051953 (rank : 98)
Query Neighborhood Hits	121	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

RAI1_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.063522 (rank : 88)
Query Neighborhood Hits	121	Target Neighborhood Hits	344	Shared Neighborhood Hits	20
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REQU_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.117199 (rank : 35)
Query Neighborhood Hits	121	Target Neighborhood Hits	519	Shared Neighborhood Hits	43
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

RSF1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.100946 (rank : 46)
Query Neighborhood Hits	121	Target Neighborhood Hits	539	Shared Neighborhood Hits	49
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SET1A_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.060140 (rank : 94)
Query Neighborhood Hits	121	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

TRI45_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.062169 (rank : 92)
Query Neighborhood Hits	121	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.061868 (rank : 93)
Query Neighborhood Hits	121	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

UHRF1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.086349 (rank : 69)
Query Neighborhood Hits	121	Target Neighborhood Hits	272	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF2_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.071646 (rank : 82)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.073105 (rank : 79)
Query Neighborhood Hits	121	Target Neighborhood Hits	275	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZMY11_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.068838 (rank : 85)
Query Neighborhood Hits	121	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.073964 (rank : 77)
Query Neighborhood Hits	121	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

PHF22_HUMAN
NC score	0.999962 (rank : 1)	θ value	1.41594e-162 (rank : 1)
Query Neighborhood Hits	121	Target Neighborhood Hits	121	Shared Neighborhood Hits	121
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
NC score	0.962905 (rank : 2)	θ value	6.17048e-150 (rank : 2)
Query Neighborhood Hits	121	Target Neighborhood Hits	89	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF1_MOUSE
NC score	0.378665 (rank : 3)	θ value	2.21117e-06 (rank : 4)
Query Neighborhood Hits	121	Target Neighborhood Hits	116	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF1_HUMAN
NC score	0.378429 (rank : 4)	θ value	2.21117e-06 (rank : 3)
Query Neighborhood Hits	121	Target Neighborhood Hits	117	Shared Neighborhood Hits	34
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

MTF2_HUMAN
NC score	0.314362 (rank : 5)	θ value	0.00134147 (rank : 8)
Query Neighborhood Hits	121	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y483, Q9UES9, Q9UP40	Gene names	MTF2
Domain Architecture
Description	Metal-response element-binding transcription factor 2 (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

MTF2_MOUSE
NC score	0.313142 (rank : 6)	θ value	0.00134147 (rank : 9)
Query Neighborhood Hits	121	Target Neighborhood Hits	126	Shared Neighborhood Hits	40
SwissProt Accessions	Q02395, Q569Z8, Q6PG89, Q8BGP9, Q8BSJ7	Gene names	Mtf2
Domain Architecture	No domain graphic available
Description	Metal-response element-binding transcription factor 2 (Zinc-regulated factor 1) (ZiRF1) (Metal-response element DNA-binding protein M96) (Metal-regulatory transcription factor 2) (PCL2).

PF21A_MOUSE
NC score	0.266269 (rank : 7)	θ value	0.000786445 (rank : 6)
Query Neighborhood Hits	121	Target Neighborhood Hits	285	Shared Neighborhood Hits	47
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21A_HUMAN
NC score	0.260949 (rank : 8)	θ value	0.000602161 (rank : 5)
Query Neighborhood Hits	121	Target Neighborhood Hits	303	Shared Neighborhood Hits	47
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

SP110_HUMAN
NC score	0.232956 (rank : 9)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	121	Target Neighborhood Hits	141	Shared Neighborhood Hits	33
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

LY10_HUMAN
NC score	0.214629 (rank : 10)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	121	Target Neighborhood Hits	151	Shared Neighborhood Hits	37
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

TIF1A_MOUSE
NC score	0.207743 (rank : 11)	θ value	0.00298849 (rank : 10)
Query Neighborhood Hits	121	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1B_MOUSE
NC score	0.204985 (rank : 12)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	121	Target Neighborhood Hits	276	Shared Neighborhood Hits	39
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1A_HUMAN
NC score	0.203754 (rank : 13)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	121	Target Neighborhood Hits	327	Shared Neighborhood Hits	40
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1B_HUMAN
NC score	0.202288 (rank : 14)	θ value	0.0330416 (rank : 17)
Query Neighborhood Hits	121	Target Neighborhood Hits	312	Shared Neighborhood Hits	38
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

PHF12_MOUSE
NC score	0.198294 (rank : 15)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	121	Target Neighborhood Hits	172	Shared Neighborhood Hits	42
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.195931 (rank : 16)	θ value	0.163984 (rank : 26)
Query Neighborhood Hits	121	Target Neighborhood Hits	174	Shared Neighborhood Hits	41
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

HRX_HUMAN
NC score	0.189311 (rank : 17)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	121	Target Neighborhood Hits	825	Shared Neighborhood Hits	58
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TRI66_MOUSE
NC score	0.187984 (rank : 18)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	121	Target Neighborhood Hits	491	Shared Neighborhood Hits	49
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TIF1G_MOUSE
NC score	0.180542 (rank : 19)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	121	Target Neighborhood Hits	498	Shared Neighborhood Hits	48
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1G_HUMAN
NC score	0.179682 (rank : 20)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	121	Target Neighborhood Hits	410	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TRI66_HUMAN
NC score	0.177715 (rank : 21)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	121	Target Neighborhood Hits	479	Shared Neighborhood Hits	49
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

PF21B_HUMAN
NC score	0.176286 (rank : 22)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	121	Target Neighborhood Hits	197	Shared Neighborhood Hits	37
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

AIRE_HUMAN
NC score	0.154160 (rank : 23)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	121	Target Neighborhood Hits	144	Shared Neighborhood Hits	39
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

MLL3_MOUSE
NC score	0.152799 (rank : 24)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	121	Target Neighborhood Hits	1399	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PF21B_MOUSE
NC score	0.152651 (rank : 25)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MLL4_HUMAN
NC score	0.152278 (rank : 26)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	121	Target Neighborhood Hits	722	Shared Neighborhood Hits	55
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

AIRE_MOUSE
NC score	0.144372 (rank : 27)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	121	Target Neighborhood Hits	196	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

MLL3_HUMAN
NC score	0.144191 (rank : 28)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	121	Target Neighborhood Hits	1644	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DPF1_MOUSE
NC score	0.141164 (rank : 29)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	121	Target Neighborhood Hits	491	Shared Neighborhood Hits	43
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MLL2_HUMAN
NC score	0.137812 (rank : 30)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	121	Target Neighborhood Hits	1788	Shared Neighborhood Hits	71
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DPF1_HUMAN
NC score	0.137424 (rank : 31)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	121	Target Neighborhood Hits	136	Shared Neighborhood Hits	42
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

BPTF_HUMAN
NC score	0.126209 (rank : 32)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	121	Target Neighborhood Hits	786	Shared Neighborhood Hits	62
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

REQU_HUMAN
NC score	0.123660 (rank : 33)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	121	Target Neighborhood Hits	523	Shared Neighborhood Hits	43
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

TF3B_MOUSE
NC score	0.117535 (rank : 34)	θ value	0.0330416 (rank : 16)
Query Neighborhood Hits	121	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CFK2	Gene names	Brf1
Domain Architecture	No domain graphic available
Description	Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B- related factor 1) (BRF-1).

REQU_MOUSE
NC score	0.117199 (rank : 35)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	121	Target Neighborhood Hits	519	Shared Neighborhood Hits	43
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

PHF13_MOUSE
NC score	0.115098 (rank : 36)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K2W6	Gene names	Phf13
Domain Architecture
Description	PHD finger protein 13.

PHF13_HUMAN
NC score	0.115009 (rank : 37)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	121	Target Neighborhood Hits	41	Shared Neighborhood Hits	14
SwissProt Accessions	Q86YI8, Q8N551, Q9UJP2	Gene names	PHF13
Domain Architecture
Description	PHD finger protein 13.

BAZ2A_HUMAN
NC score	0.115009 (rank : 38)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	121	Target Neighborhood Hits	780	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
NC score	0.111055 (rank : 39)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	121	Target Neighborhood Hits	744	Shared Neighborhood Hits	59
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
NC score	0.109691 (rank : 40)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	121	Target Neighborhood Hits	803	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

RAI1_HUMAN
NC score	0.109093 (rank : 41)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	121	Target Neighborhood Hits	360	Shared Neighborhood Hits	27
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

UHRF1_MOUSE
NC score	0.108031 (rank : 42)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	121	Target Neighborhood Hits	278	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CCDC5_HUMAN
NC score	0.104683 (rank : 43)	θ value	0.0736092 (rank : 19)
Query Neighborhood Hits	121	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q96CS2, Q8N837	Gene names	CCDC5, HEIC
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5 (Enhancer of invasion-cluster) (HEI-C).

CIR_MOUSE
NC score	0.102715 (rank : 44)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	121	Target Neighborhood Hits	255	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

MYST3_HUMAN
NC score	0.102005 (rank : 45)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	121	Target Neighborhood Hits	772	Shared Neighborhood Hits	55
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

RSF1_HUMAN
NC score	0.100946 (rank : 46)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	121	Target Neighborhood Hits	539	Shared Neighborhood Hits	49
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

JADE2_HUMAN
NC score	0.100156 (rank : 47)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	121	Target Neighborhood Hits	199	Shared Neighborhood Hits	43
SwissProt Accessions	Q9NQC1, Q6IE80, Q8TEK0, Q92513, Q96GQ6	Gene names	PHF15, JADE2, KIAA0239
Domain Architecture
Description	Protein Jade-2 (PHD finger protein 15).

CCDC5_MOUSE
NC score	0.100022 (rank : 48)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	121	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BHX1, Q3UIH2, Q8R1M1	Gene names	Ccdc5
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 5.

BAZ1A_HUMAN
NC score	0.099581 (rank : 49)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	121	Target Neighborhood Hits	693	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PKCB1_HUMAN
NC score	0.098633 (rank : 50)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	121	Target Neighborhood Hits	488	Shared Neighborhood Hits	49
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

JADE2_MOUSE
NC score	0.098408 (rank : 51)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	121	Target Neighborhood Hits	560	Shared Neighborhood Hits	51
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JADE3_MOUSE
NC score	0.095455 (rank : 52)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	121	Target Neighborhood Hits	174	Shared Neighborhood Hits	43
SwissProt Accessions	Q6IE82, Q6ZQG2	Gene names	Phf16, Jade3, Kiaa0215
Domain Architecture	No domain graphic available
Description	Protein Jade-3 (PHD finger protein 16).

NSD1_MOUSE
NC score	0.095270 (rank : 53)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	121	Target Neighborhood Hits	472	Shared Neighborhood Hits	51
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PHF10_HUMAN
NC score	0.095001 (rank : 54)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	121	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

JADE3_HUMAN
NC score	0.094656 (rank : 55)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	121	Target Neighborhood Hits	148	Shared Neighborhood Hits	41
SwissProt Accessions	Q92613, Q6IE79	Gene names	PHF16, JADE3, KIAA0215
Domain Architecture
Description	Protein Jade-3 (PHD finger protein 16).

PHF10_MOUSE
NC score	0.094272 (rank : 56)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	121	Target Neighborhood Hits	131	Shared Neighborhood Hits	37
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

MYST4_MOUSE
NC score	0.093615 (rank : 57)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	121	Target Neighborhood Hits	416	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

BRPF1_HUMAN
NC score	0.093281 (rank : 58)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	121	Target Neighborhood Hits	259	Shared Neighborhood Hits	43
SwissProt Accessions	P55201, Q9UHI0	Gene names	BRPF1, BR140
Domain Architecture
Description	Peregrin (Bromodomain and PHD finger-containing protein 1) (BR140 protein).

ARI4A_HUMAN
NC score	0.092830 (rank : 59)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	121	Target Neighborhood Hits	434	Shared Neighborhood Hits	15
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

NSD1_HUMAN
NC score	0.091476 (rank : 60)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	121	Target Neighborhood Hits	427	Shared Neighborhood Hits	46
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

MYST4_HUMAN
NC score	0.091049 (rank : 61)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	121	Target Neighborhood Hits	671	Shared Neighborhood Hits	56
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

BAZ1B_MOUSE
NC score	0.090896 (rank : 62)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	121	Target Neighborhood Hits	394	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

TAF3_MOUSE
NC score	0.090581 (rank : 63)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	121	Target Neighborhood Hits	463	Shared Neighborhood Hits	42
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BAZ1B_HUMAN
NC score	0.089972 (rank : 64)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	121	Target Neighborhood Hits	701	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

MYST3_MOUSE
NC score	0.089719 (rank : 65)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	121	Target Neighborhood Hits	688	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MAP4_HUMAN
NC score	0.087195 (rank : 66)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	121	Target Neighborhood Hits	428	Shared Neighborhood Hits	26
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

JADE1_HUMAN
NC score	0.086419 (rank : 67)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	121	Target Neighborhood Hits	140	Shared Neighborhood Hits	39
SwissProt Accessions	Q6IE81, Q4W5D5, Q6ZSL7, Q8NC41, Q96JL8, Q96SQ1, Q9H692	Gene names	PHF17, JADE1, KIAA1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

JADE1_MOUSE
NC score	0.086382 (rank : 68)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	121	Target Neighborhood Hits	160	Shared Neighborhood Hits	41
SwissProt Accessions	Q6ZPI0, Q6IE84, Q8C7S6, Q8CFM2, Q8R362	Gene names	Phf17, Jade1, Kiaa1807
Domain Architecture	No domain graphic available
Description	Protein Jade-1 (PHD finger protein 17).

UHRF1_HUMAN
NC score	0.086349 (rank : 69)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	121	Target Neighborhood Hits	272	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

JAD1A_HUMAN
NC score	0.081352 (rank : 70)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	121	Target Neighborhood Hits	328	Shared Neighborhood Hits	49
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

TAF3_HUMAN
NC score	0.079685 (rank : 71)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	121	Target Neighborhood Hits	568	Shared Neighborhood Hits	40
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BRD1_HUMAN
NC score	0.079390 (rank : 72)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	121	Target Neighborhood Hits	188	Shared Neighborhood Hits	40
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

PHF14_HUMAN
NC score	0.078575 (rank : 73)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	121	Target Neighborhood Hits	447	Shared Neighborhood Hits	52
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
NC score	0.076792 (rank : 74)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	121	Target Neighborhood Hits	342	Shared Neighborhood Hits	47
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

DOT1L_HUMAN
NC score	0.076009 (rank : 75)	θ value	0.0961366 (rank : 20)
Query Neighborhood Hits	121	Target Neighborhood Hits	660	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

BRPF3_HUMAN
NC score	0.074143 (rank : 76)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	121	Target Neighborhood Hits	217	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

ZMY11_MOUSE
NC score	0.073964 (rank : 77)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	121	Target Neighborhood Hits	198	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CHD5_HUMAN
NC score	0.073269 (rank : 78)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	121	Target Neighborhood Hits	349	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

UHRF2_MOUSE
NC score	0.073105 (rank : 79)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	121	Target Neighborhood Hits	275	Shared Neighborhood Hits	39
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

CHD4_HUMAN
NC score	0.072491 (rank : 80)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	121	Target Neighborhood Hits	365	Shared Neighborhood Hits	45
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.072200 (rank : 81)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	121	Target Neighborhood Hits	408	Shared Neighborhood Hits	42
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

UHRF2_HUMAN
NC score	0.071646 (rank : 82)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	121	Target Neighborhood Hits	269	Shared Neighborhood Hits	36
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

JAD1D_HUMAN
NC score	0.070702 (rank : 83)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	121	Target Neighborhood Hits	147	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BY66, Q92509, Q92809, Q9HCU1	Gene names	SMCY, HY, HYA, JARID1D, KIAA0234
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

CHD3_HUMAN
NC score	0.069926 (rank : 84)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	121	Target Neighborhood Hits	397	Shared Neighborhood Hits	46
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ZMY11_HUMAN
NC score	0.068838 (rank : 85)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	121	Target Neighborhood Hits	201	Shared Neighborhood Hits	33
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

MUC1_MOUSE
NC score	0.068624 (rank : 86)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	121	Target Neighborhood Hits	388	Shared Neighborhood Hits	28
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

JAD1D_MOUSE
NC score	0.065805 (rank : 87)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	121	Target Neighborhood Hits	228	Shared Neighborhood Hits	42
SwissProt Accessions	Q62240, Q9QVR9, Q9R040	Gene names	Smcy, Hya, Jarid1d
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1D (SmcY protein) (Histocompatibility Y antigen) (H-Y).

RAI1_MOUSE
NC score	0.063522 (rank : 88)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	121	Target Neighborhood Hits	344	Shared Neighborhood Hits	20
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

CSR2B_HUMAN
NC score	0.063491 (rank : 89)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	121	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H8E8, Q96GW6, Q96IH3, Q9HBF0, Q9UIY5	Gene names	CSRP2BP
Domain Architecture
Description	Cysteine-rich protein 2-binding protein (CSRP2-binding protein) (CRP2BP) (CRP2-binding partner).

JAD1C_MOUSE
NC score	0.062593 (rank : 90)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	121	Target Neighborhood Hits	164	Shared Neighborhood Hits	36
SwissProt Accessions	P41230, O54995, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039	Gene names	Smcx, Jarid1c, Xe169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein).

JAD1C_HUMAN
NC score	0.062170 (rank : 91)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	121	Target Neighborhood Hits	187	Shared Neighborhood Hits	36
SwissProt Accessions	P41229	Gene names	SMCX, DXS1272E, JARID1C, XE169
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1C (Protein SmcX) (Protein Xe169).

TRI45_HUMAN
NC score	0.062169 (rank : 92)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	121	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
NC score	0.061868 (rank : 93)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	121	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

SET1A_HUMAN
NC score	0.060140 (rank : 94)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	121	Target Neighborhood Hits	690	Shared Neighborhood Hits	28
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

CA103_MOUSE
NC score	0.054755 (rank : 95)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	121	Target Neighborhood Hits	37	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDD9, Q8C893	Gene names
Domain Architecture	No domain graphic available
Description	Protein C1orf103 homolog.

PML_HUMAN
NC score	0.054316 (rank : 96)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	121	Target Neighborhood Hits	248	Shared Neighborhood Hits	15
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

PHF11_HUMAN
NC score	0.052575 (rank : 97)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	121	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PML_MOUSE
NC score	0.051953 (rank : 98)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	121	Target Neighborhood Hits	246	Shared Neighborhood Hits	13
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

IF3X_HUMAN
NC score	0.051810 (rank : 99)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	121	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O75153, Q6AHY2, Q6P3X7, Q6ZUG8, Q8N4U7, Q9BTA3, Q9H979	Gene names	KIAA0664
Domain Architecture	No domain graphic available
Description	Putative eukaryotic translation initiation factor 3 subunit (eIF-3).

CXCC1_HUMAN
NC score	0.051559 (rank : 100)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	121	Target Neighborhood Hits	143	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P0U4, Q8N2W4, Q96BC8, Q9P2V7	Gene names	CXXC1, CGBP, PCCX1, PHF18
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

RPGR_MOUSE
NC score	0.051029 (rank : 101)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	121	Target Neighborhood Hits	281	Shared Neighborhood Hits	10
SwissProt Accessions	Q9R0X5, O88408, Q9CU92	Gene names	Rpgr
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator (mRpgr).

CXCC1_MOUSE
NC score	0.050743 (rank : 102)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	121	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CWW7	Gene names	Cxxc1, Cgbp, Pccx1
Domain Architecture
Description	CpG-binding protein (PHD finger and CXXC domain-containing protein 1) (CXXC-type zinc finger protein 1).

MINT_HUMAN
NC score	0.047860 (rank : 103)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	121	Target Neighborhood Hits	1291	Shared Neighborhood Hits	51
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CO002_HUMAN
NC score	0.047529 (rank : 104)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	121	Target Neighborhood Hits	387	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

PODXL_HUMAN
NC score	0.046460 (rank : 105)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	121	Target Neighborhood Hits	191	Shared Neighborhood Hits	9
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

WAPL_HUMAN
NC score	0.044844 (rank : 106)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	121	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z5K2, Q5VSK5, Q8IX10, Q92549	Gene names	WAPAL, FOE, KIAA0261, WAPL
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Friend of EBNA2 protein).

FXL19_HUMAN
NC score	0.043759 (rank : 107)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	121	Target Neighborhood Hits	147	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

CCNA2_HUMAN
NC score	0.043710 (rank : 108)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	121	Target Neighborhood Hits	46	Shared Neighborhood Hits	4
SwissProt Accessions	P20248	Gene names	CCNA2, CCN1, CCNA
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

CJ108_HUMAN
NC score	0.043090 (rank : 109)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	121	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

SAPS1_HUMAN
NC score	0.041231 (rank : 110)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	121	Target Neighborhood Hits	704	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

WAPL_MOUSE
NC score	0.040383 (rank : 111)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	121	Target Neighborhood Hits	158	Shared Neighborhood Hits	8
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

SRRM1_MOUSE
NC score	0.039494 (rank : 112)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	121	Target Neighborhood Hits	966	Shared Neighborhood Hits	41
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SNPC1_HUMAN
NC score	0.039249 (rank : 113)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	121	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q16533	Gene names	SNAPC1, SNAP43
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 1 (SNAPc subunit 1) (snRNA- activating protein complex 43 kDa subunit) (SNAPc 43 kDa subunit) (Small nuclear RNA-activating complex polypeptide 1) (Proximal sequence element-binding transcription factor subunit gamma) (PSE- binding factor subunit gamma) (PTF subunit gamma).

NFH_MOUSE
NC score	0.038881 (rank : 114)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	121	Target Neighborhood Hits	2247	Shared Neighborhood Hits	60
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CKAP5_HUMAN
NC score	0.038712 (rank : 115)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	121	Target Neighborhood Hits	96	Shared Neighborhood Hits	5
SwissProt Accessions	Q14008, Q14668	Gene names	CKAP5, KIAA0097
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 5 (Colonic and hepatic tumor over- expressed protein) (Ch-TOG protein).

ENL_HUMAN
NC score	0.038332 (rank : 116)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	121	Target Neighborhood Hits	305	Shared Neighborhood Hits	19
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

CSF1_HUMAN
NC score	0.037247 (rank : 117)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	121	Target Neighborhood Hits	258	Shared Neighborhood Hits	12
SwissProt Accessions	P09603, Q13130, Q14086, Q14806, Q9UQR8	Gene names	CSF1
Domain Architecture
Description	Macrophage colony-stimulating factor 1 precursor (CSF-1) (MCSF) (M- CSF) (Lanimostim).

CYLC1_HUMAN
NC score	0.036881 (rank : 118)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	121	Target Neighborhood Hits	408	Shared Neighborhood Hits	17
SwissProt Accessions	P35663, Q5JQQ9	Gene names	CYLC1, CYL, CYL1
Domain Architecture	No domain graphic available
Description	Cylicin-1 (Cylicin I) (Multiple-band polypeptide I).

JHD1B_MOUSE
NC score	0.036362 (rank : 119)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	121	Target Neighborhood Hits	214	Shared Neighborhood Hits	21
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

DPOD3_MOUSE
NC score	0.035524 (rank : 120)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	121	Target Neighborhood Hits	118	Shared Neighborhood Hits	10
SwissProt Accessions	Q9EQ28	Gene names	Pold3
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

BCAS1_HUMAN
NC score	0.034781 (rank : 121)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	121	Target Neighborhood Hits	133	Shared Neighborhood Hits	12
SwissProt Accessions	O75363, Q68CZ3	Gene names	BCAS1, AIBC1, NABC1
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 1 (Novel amplified in breast cancer 1) (Amplified and overexpressed in breast cancer).

BASP_MOUSE
NC score	0.034634 (rank : 122)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	121	Target Neighborhood Hits	260	Shared Neighborhood Hits	8
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

JHD1B_HUMAN
NC score	0.034227 (rank : 123)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	121	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

AFF1_HUMAN
NC score	0.033315 (rank : 124)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	121	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

TCAL1_MOUSE
NC score	0.033239 (rank : 125)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	121	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q921P9	Gene names	Tceal1
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Transcription elongation factor S-II protein-like 1).

DCBD2_HUMAN
NC score	0.031842 (rank : 126)	θ value	0.125558 (rank : 22)
Query Neighborhood Hits	121	Target Neighborhood Hits	118	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

FANCM_MOUSE
NC score	0.031840 (rank : 127)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	121	Target Neighborhood Hits	177	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

HTF4_HUMAN
NC score	0.030894 (rank : 128)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	121	Target Neighborhood Hits	152	Shared Neighborhood Hits	4
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

MUC5B_HUMAN
NC score	0.030207 (rank : 129)	θ value	3.0926 (rank : 68)
Query Neighborhood Hits	121	Target Neighborhood Hits	1020	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

COE3_MOUSE
NC score	0.029233 (rank : 130)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	121	Target Neighborhood Hits	60	Shared Neighborhood Hits	6
SwissProt Accessions	O08791, O08793	Gene names	Ebf3, Coe3
Domain Architecture
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

COE3_HUMAN
NC score	0.029032 (rank : 131)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	121	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H4W6, Q5T6H9, Q9H4W5	Gene names	EBF3, COE3
Domain Architecture	No domain graphic available
Description	Transcription factor COE3 (Early B-cell factor 3) (EBF-3) (Olf-1/EBF- like 2) (OE-2) (O/E-2).

TCAL3_MOUSE
NC score	0.028759 (rank : 132)	θ value	3.0926 (rank : 69)
Query Neighborhood Hits	121	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0A5, Q9CYK5, Q9D1S4	Gene names	Tceal3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

RGP2_HUMAN
NC score	0.028558 (rank : 133)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	121	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P47736	Gene names	RAP1GAP, RAP1GA1
Domain Architecture
Description	Rap1 GTPase-activating protein 1 (Rap1GAP).

ZAN_HUMAN
NC score	0.027370 (rank : 134)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	121	Target Neighborhood Hits	679	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MAP1A_HUMAN
NC score	0.027231 (rank : 135)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	121	Target Neighborhood Hits	1626	Shared Neighborhood Hits	38
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SAFB2_HUMAN
NC score	0.025715 (rank : 136)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	121	Target Neighborhood Hits	720	Shared Neighborhood Hits	15
SwissProt Accessions	Q14151, Q8TB13	Gene names	SAFB2, KIAA0138
Domain Architecture
Description	Scaffold attachment factor B2.

LRRF1_HUMAN
NC score	0.025640 (rank : 137)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	121	Target Neighborhood Hits	625	Shared Neighborhood Hits	12
SwissProt Accessions	Q32MZ4, O75766, O75799, Q32MZ5, Q53T49, Q6PKG2	Gene names	LRRFIP1, GCF2, TRIP
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (TAR RNA-interacting protein) (GC-binding factor 2).

DDX21_MOUSE
NC score	0.024482 (rank : 138)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	121	Target Neighborhood Hits	350	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JIK5, Q9WV45	Gene names	Ddx21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

PHLB2_HUMAN
NC score	0.024393 (rank : 139)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	121	Target Neighborhood Hits	964	Shared Neighborhood Hits	30
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SQSTM_HUMAN
NC score	0.024241 (rank : 140)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	121	Target Neighborhood Hits	61	Shared Neighborhood Hits	8
SwissProt Accessions	Q13501, Q13446, Q9BUV7, Q9BVS6, Q9UEU1	Gene names	SQSTM1, ORCA
Domain Architecture	No domain graphic available
Description	Sequestosome-1 (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (EBI3-associated protein of 60 kDa) (p60) (EBIAP).

SIN3B_MOUSE
NC score	0.023888 (rank : 141)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	121	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q62141, O54976, Q6A013, Q8VCB8, Q8VDZ5	Gene names	Sin3b, Kiaa0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

RIMS1_HUMAN
NC score	0.022579 (rank : 142)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	121	Target Neighborhood Hits	437	Shared Neighborhood Hits	14
SwissProt Accessions	Q86UR5, O15048, Q8TDY9, Q8TDZ5, Q9HBA1, Q9HBA2, Q9HBA3, Q9HBA4, Q9HBA5, Q9HBA6	Gene names	RIMS1, KIAA0340, RIM1
Domain Architecture
Description	Regulating synaptic membrane exocytosis protein 1 (Rab3-interacting molecule 1) (RIM 1).

NFH_HUMAN
NC score	0.022203 (rank : 143)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	121	Target Neighborhood Hits	1242	Shared Neighborhood Hits	30
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

UBP31_HUMAN
NC score	0.020832 (rank : 144)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	121	Target Neighborhood Hits	293	Shared Neighborhood Hits	14
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

ANK2_HUMAN
NC score	0.020759 (rank : 145)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	121	Target Neighborhood Hits	1615	Shared Neighborhood Hits	51
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

S18L1_HUMAN
NC score	0.020623 (rank : 146)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	121	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	O75177, Q5JXJ3, Q8NE69, Q9BR55, Q9H4K6	Gene names	SS18L1, KIAA0693
Domain Architecture
Description	SS18-like protein 1 (SYT homolog 1).

DDX21_HUMAN
NC score	0.020192 (rank : 147)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	121	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

RP3A_MOUSE
NC score	0.020066 (rank : 148)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	121	Target Neighborhood Hits	510	Shared Neighborhood Hits	27
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CEP70_HUMAN
NC score	0.019046 (rank : 149)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	121	Target Neighborhood Hits	432	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NHQ1, Q96B31, Q9H2C3, Q9H2Z1, Q9H940	Gene names	CEP70, BITE
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein) (p10-binding protein).

MORC2_HUMAN
NC score	0.018789 (rank : 150)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	121	Target Neighborhood Hits	207	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

EEA1_MOUSE
NC score	0.017790 (rank : 151)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	121	Target Neighborhood Hits	1637	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

COHA1_MOUSE
NC score	0.016706 (rank : 152)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	121	Target Neighborhood Hits	414	Shared Neighborhood Hits	15
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

UBQL3_MOUSE
NC score	0.016669 (rank : 153)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	121	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

HCFC1_MOUSE
NC score	0.015936 (rank : 154)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	121	Target Neighborhood Hits	348	Shared Neighborhood Hits	16
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HERC2_HUMAN
NC score	0.014900 (rank : 155)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	121	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	O95714, Q86SV7, Q86SV8, Q86SV9, Q86YY3, Q86YY4, Q86YY5, Q86YY6, Q86YY7, Q86YY8, Q86YY9, Q86YZ0, Q86YZ1	Gene names	HERC2
Domain Architecture	No domain graphic available
Description	HECT domain and RCC1-like domain-containing protein 2.

LIMD1_HUMAN
NC score	0.014511 (rank : 156)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	121	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UGP4, Q9BQQ9, Q9NQ47	Gene names	LIMD1
Domain Architecture
Description	LIM domain-containing protein 1.

PRGR_MOUSE
NC score	0.014449 (rank : 157)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	121	Target Neighborhood Hits	286	Shared Neighborhood Hits	12
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

ELF4_HUMAN
NC score	0.010411 (rank : 158)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	121	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	Q99607, O60435	Gene names	ELF4, ELFR, MEF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor).

RPGF2_HUMAN
NC score	0.010109 (rank : 159)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	121	Target Neighborhood Hits	242	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4G8	Gene names	RAPGEF2, KIAA0313, NRAPGEP, PDZGEF1
Domain Architecture	No domain graphic available
Description	Rap guanine nucleotide exchange factor 2 (Neural RAP guanine nucleotide exchange protein) (nRap GEP) (PDZ domain-containing guanine nucleotide exchange factor 1) (PDZ-GEF1) (RA-GEF).

ECT2_MOUSE
NC score	0.009070 (rank : 160)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	121	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q07139	Gene names	Ect2
Domain Architecture
Description	ECT2 protein (Epithelial cell-transforming sequence 2 oncogene).

WNK2_HUMAN
NC score	0.007992 (rank : 161)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	121	Target Neighborhood Hits	1407	Shared Neighborhood Hits	34
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

TITIN_HUMAN
NC score	0.007105 (rank : 162)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	121	Target Neighborhood Hits	2923	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MAST2_MOUSE
NC score	0.005952 (rank : 163)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	121	Target Neighborhood Hits	1110	Shared Neighborhood Hits	19
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

VGFR1_HUMAN
NC score	0.002994 (rank : 164)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	121	Target Neighborhood Hits	1109	Shared Neighborhood Hits	7
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

KPCI_HUMAN
NC score	0.002700 (rank : 165)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	121	Target Neighborhood Hits	885	Shared Neighborhood Hits	7
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

KPCI_MOUSE
NC score	0.002697 (rank : 166)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	121	Target Neighborhood Hits	888	Shared Neighborhood Hits	7
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

ZN583_MOUSE
NC score	-0.000005 (rank : 167)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	121	Target Neighborhood Hits	774	Shared Neighborhood Hits	5
SwissProt Accessions	Q3V080, Q3V3L4	Gene names	Znf583, Zfp583
Domain Architecture	No domain graphic available
Description	Zinc finger protein 583.