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Network neighborhood for query Sequence : TRI45_HUMAN

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TRI45_HUMAN
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRI45_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
θ value	0 (rank : 2)	NC score	0.990801 (rank : 2)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRIM3_HUMAN
θ value	1.42001e-37 (rank : 3)	NC score	0.734423 (rank : 6)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	122
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_MOUSE
θ value	2.42216e-37 (rank : 4)	NC score	0.731136 (rank : 8)
Query Neighborhood Hits	155	Target Neighborhood Hits	331	Shared Neighborhood Hits	119
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRIM3_MOUSE
θ value	3.16345e-37 (rank : 5)	NC score	0.736556 (rank : 5)
Query Neighborhood Hits	155	Target Neighborhood Hits	351	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM2_HUMAN
θ value	7.04741e-37 (rank : 6)	NC score	0.731942 (rank : 7)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TIF1G_HUMAN
θ value	3.06405e-32 (rank : 7)	NC score	0.683546 (rank : 11)
Query Neighborhood Hits	155	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	4.00176e-32 (rank : 8)	NC score	0.675014 (rank : 12)
Query Neighborhood Hits	155	Target Neighborhood Hits	498	Shared Neighborhood Hits	101
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1A_HUMAN
θ value	3.17079e-29 (rank : 9)	NC score	0.632327 (rank : 17)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	88
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRI56_MOUSE
θ value	1.73987e-27 (rank : 10)	NC score	0.771334 (rank : 3)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	112
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TIF1A_MOUSE
θ value	5.06226e-27 (rank : 11)	NC score	0.615665 (rank : 22)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	86
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TRI56_HUMAN
θ value	9.54697e-26 (rank : 12)	NC score	0.744478 (rank : 4)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TIF1B_HUMAN
θ value	3.51386e-20 (rank : 13)	NC score	0.708111 (rank : 9)
Query Neighborhood Hits	155	Target Neighborhood Hits	312	Shared Neighborhood Hits	92
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
θ value	4.58923e-20 (rank : 14)	NC score	0.704826 (rank : 10)
Query Neighborhood Hits	155	Target Neighborhood Hits	276	Shared Neighborhood Hits	91
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TRI36_HUMAN
θ value	2.97466e-19 (rank : 15)	NC score	0.673145 (rank : 13)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	1.63225e-17 (rank : 16)	NC score	0.666653 (rank : 14)
Query Neighborhood Hits	155	Target Neighborhood Hits	266	Shared Neighborhood Hits	111
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRIM1_MOUSE
θ value	3.07829e-16 (rank : 17)	NC score	0.629705 (rank : 19)
Query Neighborhood Hits	155	Target Neighborhood Hits	361	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM1_HUMAN
θ value	4.02038e-16 (rank : 18)	NC score	0.631649 (rank : 18)
Query Neighborhood Hits	155	Target Neighborhood Hits	345	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRI42_MOUSE
θ value	9.90251e-15 (rank : 19)	NC score	0.637897 (rank : 16)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	98
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_HUMAN
θ value	1.29331e-14 (rank : 20)	NC score	0.640828 (rank : 15)
Query Neighborhood Hits	155	Target Neighborhood Hits	283	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI46_HUMAN
θ value	5.43371e-13 (rank : 21)	NC score	0.623563 (rank : 21)
Query Neighborhood Hits	155	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	7.09661e-13 (rank : 22)	NC score	0.623894 (rank : 20)
Query Neighborhood Hits	155	Target Neighborhood Hits	287	Shared Neighborhood Hits	115
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

PML_HUMAN
θ value	6.00763e-12 (rank : 23)	NC score	0.593797 (rank : 26)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	89
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRI18_HUMAN
θ value	7.84624e-12 (rank : 24)	NC score	0.595730 (rank : 25)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	115
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	2.28291e-11 (rank : 25)	NC score	0.602443 (rank : 24)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	116
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

PML_MOUSE
θ value	6.64225e-11 (rank : 26)	NC score	0.604100 (rank : 23)
Query Neighborhood Hits	155	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI66_HUMAN
θ value	1.133e-10 (rank : 27)	NC score	0.457968 (rank : 41)
Query Neighborhood Hits	155	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	1.25267e-09 (rank : 28)	NC score	0.460981 (rank : 39)
Query Neighborhood Hits	155	Target Neighborhood Hits	491	Shared Neighborhood Hits	64
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRIM8_HUMAN
θ value	4.76016e-09 (rank : 29)	NC score	0.505447 (rank : 35)
Query Neighborhood Hits	155	Target Neighborhood Hits	650	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	1.38499e-08 (rank : 30)	NC score	0.506521 (rank : 34)
Query Neighborhood Hits	155	Target Neighborhood Hits	674	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

FLNC_HUMAN
θ value	3.08544e-08 (rank : 31)	NC score	0.202938 (rank : 123)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

TRIM9_MOUSE
θ value	3.08544e-08 (rank : 32)	NC score	0.545377 (rank : 30)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRIM9_HUMAN
θ value	5.26297e-08 (rank : 33)	NC score	0.562266 (rank : 27)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

FLNA_HUMAN
θ value	5.81887e-07 (rank : 34)	NC score	0.200093 (rank : 125)
Query Neighborhood Hits	155	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_MOUSE
θ value	5.81887e-07 (rank : 35)	NC score	0.200112 (rank : 124)
Query Neighborhood Hits	155	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNB_MOUSE
θ value	1.69304e-06 (rank : 36)	NC score	0.195376 (rank : 126)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

FLNB_HUMAN
θ value	2.88788e-06 (rank : 37)	NC score	0.194577 (rank : 127)
Query Neighborhood Hits	155	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

TRI47_MOUSE
θ value	2.88788e-06 (rank : 38)	NC score	0.449786 (rank : 45)
Query Neighborhood Hits	155	Target Neighborhood Hits	295	Shared Neighborhood Hits	112
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI59_HUMAN
θ value	6.43352e-06 (rank : 39)	NC score	0.504968 (rank : 36)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI54_MOUSE
θ value	1.43324e-05 (rank : 40)	NC score	0.556794 (rank : 28)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI13_HUMAN
θ value	2.44474e-05 (rank : 41)	NC score	0.463962 (rank : 38)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	119
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI59_MOUSE
θ value	2.44474e-05 (rank : 42)	NC score	0.494795 (rank : 37)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	114
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

ARD1_MOUSE
θ value	3.19293e-05 (rank : 43)	NC score	0.285083 (rank : 75)
Query Neighborhood Hits	155	Target Neighborhood Hits	573	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRI54_HUMAN
θ value	3.19293e-05 (rank : 44)	NC score	0.552099 (rank : 29)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI13_MOUSE
θ value	0.000121331 (rank : 45)	NC score	0.459993 (rank : 40)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	119
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI16_MOUSE
θ value	0.000158464 (rank : 46)	NC score	0.378942 (rank : 50)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	79
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI55_HUMAN
θ value	0.000158464 (rank : 47)	NC score	0.538050 (rank : 33)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

ARD1_HUMAN
θ value	0.00020696 (rank : 48)	NC score	0.270579 (rank : 95)
Query Neighborhood Hits	155	Target Neighborhood Hits	621	Shared Neighborhood Hits	82
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

TRI47_HUMAN
θ value	0.00020696 (rank : 49)	NC score	0.451015 (rank : 44)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	113
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI63_HUMAN
θ value	0.00020696 (rank : 50)	NC score	0.544911 (rank : 31)
Query Neighborhood Hits	155	Target Neighborhood Hits	298	Shared Neighborhood Hits	111
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI29_MOUSE
θ value	0.00035302 (rank : 51)	NC score	0.448186 (rank : 46)
Query Neighborhood Hits	155	Target Neighborhood Hits	306	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI16_HUMAN
θ value	0.000461057 (rank : 52)	NC score	0.321233 (rank : 60)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	78
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI29_HUMAN
θ value	0.000602161 (rank : 53)	NC score	0.442411 (rank : 47)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	78
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI63_MOUSE
θ value	0.000602161 (rank : 54)	NC score	0.540057 (rank : 32)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	108
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI32_HUMAN
θ value	0.000786445 (rank : 55)	NC score	0.455590 (rank : 42)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	112
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI25_MOUSE
θ value	0.00102713 (rank : 56)	NC score	0.428885 (rank : 48)
Query Neighborhood Hits	155	Target Neighborhood Hits	446	Shared Neighborhood Hits	120
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI32_MOUSE
θ value	0.00102713 (rank : 57)	NC score	0.451111 (rank : 43)
Query Neighborhood Hits	155	Target Neighborhood Hits	271	Shared Neighborhood Hits	111
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

K0157_HUMAN
θ value	0.00298849 (rank : 58)	NC score	0.125326 (rank : 172)
Query Neighborhood Hits	155	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

K0157_MOUSE
θ value	0.00390308 (rank : 59)	NC score	0.122610 (rank : 177)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TCJ1, Q3TB08, Q8K0R4	Gene names	Kiaa0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

TRI41_HUMAN
θ value	0.00665767 (rank : 60)	NC score	0.294770 (rank : 65)
Query Neighborhood Hits	155	Target Neighborhood Hits	349	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI25_HUMAN
θ value	0.0113563 (rank : 61)	NC score	0.420578 (rank : 49)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	121
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI34_HUMAN
θ value	0.0113563 (rank : 62)	NC score	0.288138 (rank : 72)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI50_MOUSE
θ value	0.0148317 (rank : 63)	NC score	0.333941 (rank : 58)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	119
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI68_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.257028 (rank : 106)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRIM6_HUMAN
θ value	0.0330416 (rank : 65)	NC score	0.278483 (rank : 83)
Query Neighborhood Hits	155	Target Neighborhood Hits	412	Shared Neighborhood Hits	118
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI14_MOUSE
θ value	0.0431538 (rank : 66)	NC score	0.312472 (rank : 61)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI68_MOUSE
θ value	0.0431538 (rank : 67)	NC score	0.273678 (rank : 92)
Query Neighborhood Hits	155	Target Neighborhood Hits	356	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRIM6_MOUSE
θ value	0.0431538 (rank : 68)	NC score	0.276012 (rank : 88)
Query Neighborhood Hits	155	Target Neighborhood Hits	451	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

ZN313_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.275792 (rank : 89)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRI39_MOUSE
θ value	0.0563607 (rank : 70)	NC score	0.278994 (rank : 82)
Query Neighborhood Hits	155	Target Neighborhood Hits	691	Shared Neighborhood Hits	118
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI50_HUMAN
θ value	0.0563607 (rank : 71)	NC score	0.329694 (rank : 59)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	118
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

ZN313_MOUSE
θ value	0.0563607 (rank : 72)	NC score	0.283650 (rank : 77)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	100
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI27_HUMAN
θ value	0.0736092 (rank : 73)	NC score	0.279520 (rank : 81)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	111
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI17_MOUSE
θ value	0.0961366 (rank : 74)	NC score	0.279945 (rank : 80)
Query Neighborhood Hits	155	Target Neighborhood Hits	620	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI27_MOUSE
θ value	0.0961366 (rank : 75)	NC score	0.277841 (rank : 84)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	109
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

ITAL_HUMAN
θ value	0.125558 (rank : 76)	NC score	0.017279 (rank : 311)
Query Neighborhood Hits	155	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	P20701, O43746, Q45H73, Q9UBC8	Gene names	ITGAL, CD11A
Domain Architecture
Description	Integrin alpha-L precursor (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD11a antigen).

TRI14_HUMAN
θ value	0.125558 (rank : 77)	NC score	0.309534 (rank : 62)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	87
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI65_HUMAN
θ value	0.125558 (rank : 78)	NC score	0.362977 (rank : 55)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

RNF39_HUMAN
θ value	0.163984 (rank : 79)	NC score	0.270088 (rank : 96)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRAF6_MOUSE
θ value	0.163984 (rank : 80)	NC score	0.131323 (rank : 164)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	86
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

TRIM5_HUMAN
θ value	0.21417 (rank : 81)	NC score	0.285172 (rank : 74)
Query Neighborhood Hits	155	Target Neighborhood Hits	424	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

MEFV_MOUSE
θ value	0.279714 (rank : 82)	NC score	0.277380 (rank : 86)
Query Neighborhood Hits	155	Target Neighborhood Hits	236	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

RN152_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.260628 (rank : 105)
Query Neighborhood Hits	155	Target Neighborhood Hits	107	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	0.365318 (rank : 84)	NC score	0.261869 (rank : 104)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRI22_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.283817 (rank : 76)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRI65_MOUSE
θ value	0.365318 (rank : 86)	NC score	0.340869 (rank : 57)
Query Neighborhood Hits	155	Target Neighborhood Hits	340	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI73_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.368567 (rank : 52)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI74_HUMAN
θ value	0.47712 (rank : 88)	NC score	0.370919 (rank : 51)
Query Neighborhood Hits	155	Target Neighborhood Hits	249	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

RN168_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.264574 (rank : 100)
Query Neighborhood Hits	155	Target Neighborhood Hits	440	Shared Neighborhood Hits	99
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RO52_HUMAN
θ value	0.62314 (rank : 90)	NC score	0.263433 (rank : 102)
Query Neighborhood Hits	155	Target Neighborhood Hits	419	Shared Neighborhood Hits	121
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

STAB1_MOUSE
θ value	0.62314 (rank : 91)	NC score	0.007637 (rank : 319)
Query Neighborhood Hits	155	Target Neighborhood Hits	566	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

SYCP1_MOUSE
θ value	0.62314 (rank : 92)	NC score	0.027717 (rank : 306)
Query Neighborhood Hits	155	Target Neighborhood Hits	1456	Shared Neighborhood Hits	47
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRAF5_MOUSE
θ value	0.62314 (rank : 93)	NC score	0.092925 (rank : 218)
Query Neighborhood Hits	155	Target Neighborhood Hits	355	Shared Neighborhood Hits	78
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

GOGA3_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.024308 (rank : 308)
Query Neighborhood Hits	155	Target Neighborhood Hits	1437	Shared Neighborhood Hits	44
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

TRI40_HUMAN
θ value	1.06291 (rank : 95)	NC score	0.296782 (rank : 64)
Query Neighborhood Hits	155	Target Neighborhood Hits	279	Shared Neighborhood Hits	104
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

EGLN1_HUMAN
θ value	1.38821 (rank : 96)	NC score	0.029865 (rank : 305)
Query Neighborhood Hits	155	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

MEFV_HUMAN
θ value	1.38821 (rank : 97)	NC score	0.206178 (rank : 120)
Query Neighborhood Hits	155	Target Neighborhood Hits	431	Shared Neighborhood Hits	91
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MYH3_HUMAN
θ value	1.38821 (rank : 98)	NC score	0.007415 (rank : 320)
Query Neighborhood Hits	155	Target Neighborhood Hits	1660	Shared Neighborhood Hits	45
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

RN168_HUMAN
θ value	1.38821 (rank : 99)	NC score	0.268800 (rank : 98)
Query Neighborhood Hits	155	Target Neighborhood Hits	370	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRAF7_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.093153 (rank : 217)
Query Neighborhood Hits	155	Target Neighborhood Hits	482	Shared Neighborhood Hits	86
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRI15_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.280386 (rank : 79)
Query Neighborhood Hits	155	Target Neighborhood Hits	395	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI31_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.346388 (rank : 56)
Query Neighborhood Hits	155	Target Neighborhood Hits	299	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

MNAB_HUMAN
θ value	1.81305 (rank : 103)	NC score	0.120003 (rank : 183)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	1.81305 (rank : 104)	NC score	0.119927 (rank : 184)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	84
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

REST_HUMAN
θ value	1.81305 (rank : 105)	NC score	0.015412 (rank : 312)
Query Neighborhood Hits	155	Target Neighborhood Hits	1605	Shared Neighborhood Hits	48
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

TRI10_MOUSE
θ value	1.81305 (rank : 106)	NC score	0.289333 (rank : 71)
Query Neighborhood Hits	155	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI17_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.268447 (rank : 99)
Query Neighborhood Hits	155	Target Neighborhood Hits	318	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI34_MOUSE
θ value	1.81305 (rank : 108)	NC score	0.251830 (rank : 111)
Query Neighborhood Hits	155	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI60_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.262432 (rank : 103)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	109
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

TRIM7_HUMAN
θ value	1.81305 (rank : 110)	NC score	0.274675 (rank : 90)
Query Neighborhood Hits	155	Target Neighborhood Hits	336	Shared Neighborhood Hits	112
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

CTRO_MOUSE
θ value	2.36792 (rank : 111)	NC score	0.003943 (rank : 325)
Query Neighborhood Hits	155	Target Neighborhood Hits	2344	Shared Neighborhood Hits	45
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EGLN1_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.025856 (rank : 307)
Query Neighborhood Hits	155	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

RN183_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.290429 (rank : 70)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RN183_MOUSE
θ value	2.36792 (rank : 114)	NC score	0.273295 (rank : 94)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	72
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI10_HUMAN
θ value	2.36792 (rank : 115)	NC score	0.282573 (rank : 78)
Query Neighborhood Hits	155	Target Neighborhood Hits	315	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI30_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.287471 (rank : 73)
Query Neighborhood Hits	155	Target Neighborhood Hits	434	Shared Neighborhood Hits	118
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

GOGA3_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.010850 (rank : 316)
Query Neighborhood Hits	155	Target Neighborhood Hits	1317	Shared Neighborhood Hits	33
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

K1C19_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.004485 (rank : 323)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	P19001	Gene names	Krt19, Krt1-19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

TRAF7_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.088522 (rank : 225)
Query Neighborhood Hits	155	Target Neighborhood Hits	470	Shared Neighborhood Hits	85
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

TRI49_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.208712 (rank : 119)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI52_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.277607 (rank : 85)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	103
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRIM4_HUMAN
θ value	3.0926 (rank : 122)	NC score	0.273680 (rank : 91)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	111
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

UB7I3_MOUSE
θ value	3.0926 (rank : 123)	NC score	0.073108 (rank : 245)
Query Neighborhood Hits	155	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

KPCT_HUMAN
θ value	4.03905 (rank : 124)	NC score	-0.003227 (rank : 331)
Query Neighborhood Hits	155	Target Neighborhood Hits	897	Shared Neighborhood Hits	7
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	4.03905 (rank : 125)	NC score	-0.003173 (rank : 330)
Query Neighborhood Hits	155	Target Neighborhood Hits	895	Shared Neighborhood Hits	7
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

MYCB2_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.021639 (rank : 309)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

RC3H1_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.127813 (rank : 171)
Query Neighborhood Hits	155	Target Neighborhood Hits	244	Shared Neighborhood Hits	93
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

TRI37_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.367465 (rank : 53)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	98
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	4.03905 (rank : 129)	NC score	0.367201 (rank : 54)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	98
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

BRCA1_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.193849 (rank : 128)
Query Neighborhood Hits	155	Target Neighborhood Hits	381	Shared Neighborhood Hits	93
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BRCA1_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.192290 (rank : 130)
Query Neighborhood Hits	155	Target Neighborhood Hits	436	Shared Neighborhood Hits	93
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RC3H1_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.120543 (rank : 181)
Query Neighborhood Hits	155	Target Neighborhood Hits	433	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

SYCP1_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.013296 (rank : 314)
Query Neighborhood Hits	155	Target Neighborhood Hits	1313	Shared Neighborhood Hits	31
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRI26_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.264242 (rank : 101)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	107
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRIM7_MOUSE
θ value	5.27518 (rank : 135)	NC score	0.290785 (rank : 69)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	118
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

ZN385_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.013695 (rank : 313)
Query Neighborhood Hits	155	Target Neighborhood Hits	614	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

ATP4A_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.003368 (rank : 327)
Query Neighborhood Hits	155	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q64436, Q9CV46	Gene names	Atp4a
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

CNTN6_MOUSE
θ value	6.88961 (rank : 138)	NC score	-0.000267 (rank : 329)
Query Neighborhood Hits	155	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

GOLI_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.064066 (rank : 267)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

IMMT_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.009195 (rank : 317)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

K1C15_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.004308 (rank : 324)
Query Neighborhood Hits	155	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

ZN254_HUMAN
θ value	6.88961 (rank : 142)	NC score	-0.004740 (rank : 332)
Query Neighborhood Hits	155	Target Neighborhood Hits	702	Shared Neighborhood Hits	4
SwissProt Accessions	O75437	Gene names	ZNF254, BMZF5
Domain Architecture
Description	Zinc finger protein 254 (Bone marrow zinc finger 5) (BMZF-5) (Hematopoietic cell-derived zinc finger protein 1) (HD-ZNF1).

ZN539_HUMAN
θ value	6.88961 (rank : 143)	NC score	-0.005318 (rank : 333)
Query Neighborhood Hits	155	Target Neighborhood Hits	758	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XL7	Gene names	ZNF539
Domain Architecture	No domain graphic available
Description	Zinc finger protein 539.

ATP4A_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.003073 (rank : 328)
Query Neighborhood Hits	155	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	P20648, O00738	Gene names	ATP4A
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

BICD2_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.006147 (rank : 322)
Query Neighborhood Hits	155	Target Neighborhood Hits	864	Shared Neighborhood Hits	21
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CCD21_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.007702 (rank : 318)
Query Neighborhood Hits	155	Target Neighborhood Hits	1228	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

FYCO1_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.011078 (rank : 315)
Query Neighborhood Hits	155	Target Neighborhood Hits	1149	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

K1C13_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.003927 (rank : 326)
Query Neighborhood Hits	155	Target Neighborhood Hits	386	Shared Neighborhood Hits	15
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

LNX1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.110945 (rank : 200)
Query Neighborhood Hits	155	Target Neighborhood Hits	379	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX1_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.114813 (rank : 192)
Query Neighborhood Hits	155	Target Neighborhood Hits	377	Shared Neighborhood Hits	81
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

LNX2_MOUSE
θ value	8.99809 (rank : 151)	NC score	0.121561 (rank : 179)
Query Neighborhood Hits	155	Target Neighborhood Hits	407	Shared Neighborhood Hits	87
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

MYCB2_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.020272 (rank : 310)
Query Neighborhood Hits	155	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NCKPL_HUMAN
θ value	8.99809 (rank : 153)	NC score	0.006609 (rank : 321)
Query Neighborhood Hits	155	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P55160	Gene names	NCKAP1L, HEM1
Domain Architecture	No domain graphic available
Description	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1).

TRI12_MOUSE
θ value	8.99809 (rank : 154)	NC score	0.302885 (rank : 63)
Query Neighborhood Hits	155	Target Neighborhood Hits	387	Shared Neighborhood Hits	112
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI26_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.273372 (rank : 93)
Query Neighborhood Hits	155	Target Neighborhood Hits	335	Shared Neighborhood Hits	108
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

AIRE_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.135423 (rank : 162)
Query Neighborhood Hits	155	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.136039 (rank : 161)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AMD_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.089384 (rank : 223)
Query Neighborhood Hits	155	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P19021, O95080, Q16252, Q16253, Q86U53, Q8WVC7, Q9UCG0	Gene names	PAM
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

AMD_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.074478 (rank : 241)
Query Neighborhood Hits	155	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	P97467	Gene names	Pam
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

AMFR2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.075439 (rank : 237)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

AMFR_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.075540 (rank : 236)
Query Neighborhood Hits	155	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.078387 (rank : 231)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.061723 (rank : 271)
Query Neighborhood Hits	155	Target Neighborhood Hits	701	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.068021 (rank : 260)
Query Neighborhood Hits	155	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.112186 (rank : 198)
Query Neighborhood Hits	155	Target Neighborhood Hits	780	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.108470 (rank : 204)
Query Neighborhood Hits	155	Target Neighborhood Hits	744	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.094938 (rank : 214)
Query Neighborhood Hits	155	Target Neighborhood Hits	803	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BFAR_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.170162 (rank : 140)
Query Neighborhood Hits	155	Target Neighborhood Hits	222	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BFAR_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.157969 (rank : 152)
Query Neighborhood Hits	155	Target Neighborhood Hits	232	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BIRC7_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.103305 (rank : 208)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	80
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BPTF_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.094777 (rank : 215)
Query Neighborhood Hits	155	Target Neighborhood Hits	786	Shared Neighborhood Hits	16
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

BRD2_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.078177 (rank : 232)
Query Neighborhood Hits	155	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.067480 (rank : 261)
Query Neighborhood Hits	155	Target Neighborhood Hits	369	Shared Neighborhood Hits	12
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.067404 (rank : 262)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

BRD4_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.061447 (rank : 272)
Query Neighborhood Hits	155	Target Neighborhood Hits	851	Shared Neighborhood Hits	16
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

BRD4_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.061956 (rank : 270)
Query Neighborhood Hits	155	Target Neighborhood Hits	845	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BRD8_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.050040 (rank : 304)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

BRDT_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.070377 (rank : 255)
Query Neighborhood Hits	155	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.070216 (rank : 256)
Query Neighborhood Hits	155	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

BSPRY_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.176534 (rank : 136)
Query Neighborhood Hits	155	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.170100 (rank : 141)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	67
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BT1A1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.122991 (rank : 175)
Query Neighborhood Hits	155	Target Neighborhood Hits	322	Shared Neighborhood Hits	51
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.122741 (rank : 176)
Query Neighborhood Hits	155	Target Neighborhood Hits	252	Shared Neighborhood Hits	51
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT2A1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.104736 (rank : 207)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	48
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BT2A2_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.113611 (rank : 194)
Query Neighborhood Hits	155	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BT2A3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.101711 (rank : 209)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BT3A1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.116593 (rank : 190)
Query Neighborhood Hits	155	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

BT3A3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.117032 (rank : 189)
Query Neighborhood Hits	155	Target Neighborhood Hits	233	Shared Neighborhood Hits	49
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BTNL3_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.112677 (rank : 195)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL8_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.101088 (rank : 210)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

BTNL9_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.112528 (rank : 196)
Query Neighborhood Hits	155	Target Neighborhood Hits	125	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

CBLB_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.072435 (rank : 248)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	64
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.072711 (rank : 247)
Query Neighborhood Hits	155	Target Neighborhood Hits	277	Shared Neighborhood Hits	65
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLC_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.089219 (rank : 224)
Query Neighborhood Hits	155	Target Neighborhood Hits	173	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

CBLC_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.092438 (rank : 219)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	53
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

CBL_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.072725 (rank : 246)
Query Neighborhood Hits	155	Target Neighborhood Hits	353	Shared Neighborhood Hits	64
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBL_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.071412 (rank : 251)
Query Neighborhood Hits	155	Target Neighborhood Hits	426	Shared Neighborhood Hits	65
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

CBP_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.054606 (rank : 293)
Query Neighborhood Hits	155	Target Neighborhood Hits	941	Shared Neighborhood Hits	9
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.052204 (rank : 299)
Query Neighborhood Hits	155	Target Neighborhood Hits	1051	Shared Neighborhood Hits	7
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CECR2_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.079562 (rank : 230)
Query Neighborhood Hits	155	Target Neighborhood Hits	543	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CHD3_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.050453 (rank : 303)
Query Neighborhood Hits	155	Target Neighborhood Hits	397	Shared Neighborhood Hits	12
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.052023 (rank : 301)
Query Neighborhood Hits	155	Target Neighborhood Hits	365	Shared Neighborhood Hits	12
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.052153 (rank : 300)
Query Neighborhood Hits	155	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.053906 (rank : 296)
Query Neighborhood Hits	155	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHFR_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.169937 (rank : 142)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	82
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.169936 (rank : 143)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	80
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CM007_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.064537 (rank : 266)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	61
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

CM007_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.076361 (rank : 235)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

DTX3L_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.068244 (rank : 259)
Query Neighborhood Hits	155	Target Neighborhood Hits	187	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

DTX3_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.118010 (rank : 188)
Query Neighborhood Hits	155	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

DTX3_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.120161 (rank : 182)
Query Neighborhood Hits	155	Target Neighborhood Hits	202	Shared Neighborhood Hits	75
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

EP300_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.054655 (rank : 292)
Query Neighborhood Hits	155	Target Neighborhood Hits	821	Shared Neighborhood Hits	9
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

ERMAP_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.129340 (rank : 167)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

ERMAP_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.118721 (rank : 185)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

FSD1L_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.183240 (rank : 133)
Query Neighborhood Hits	155	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

FSD1L_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.223138 (rank : 116)
Query Neighborhood Hits	155	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

GCNL2_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.070870 (rank : 254)
Query Neighborhood Hits	155	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

GCNL2_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.066338 (rank : 263)
Query Neighborhood Hits	155	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

GOLI_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.061016 (rank : 275)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

LNX2_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.121180 (rank : 180)
Query Neighborhood Hits	155	Target Neighborhood Hits	389	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

LY10_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.172399 (rank : 139)
Query Neighborhood Hits	155	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MGRN1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.054717 (rank : 291)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

MGRN1_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.053824 (rank : 297)
Query Neighborhood Hits	155	Target Neighborhood Hits	149	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

NHLC1_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.204100 (rank : 121)
Query Neighborhood Hits	155	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.228421 (rank : 114)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NSD1_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.070067 (rank : 257)
Query Neighborhood Hits	155	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.071385 (rank : 252)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	13
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PB1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.058645 (rank : 284)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	7
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PCAF_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.068475 (rank : 258)
Query Neighborhood Hits	155	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

PCGF6_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.059008 (rank : 281)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.062334 (rank : 268)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PEX10_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.179428 (rank : 135)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PF21A_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.110111 (rank : 201)
Query Neighborhood Hits	155	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.111797 (rank : 199)
Query Neighborhood Hits	155	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.087145 (rank : 226)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.077372 (rank : 233)
Query Neighborhood Hits	155	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.098222 (rank : 212)
Query Neighborhood Hits	155	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.098086 (rank : 213)
Query Neighborhood Hits	155	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.061082 (rank : 274)
Query Neighborhood Hits	155	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

PHF1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.059003 (rank : 282)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

PHF22_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.062169 (rank : 269)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PHF22_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.051373 (rank : 302)
Query Neighborhood Hits	155	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

PKCB1_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.115181 (rank : 191)
Query Neighborhood Hits	155	Target Neighborhood Hits	488	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PZRN3_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.073340 (rank : 244)
Query Neighborhood Hits	155	Target Neighborhood Hits	461	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN3_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.074634 (rank : 239)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	81
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

PZRN4_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.074295 (rank : 242)
Query Neighborhood Hits	155	Target Neighborhood Hits	438	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

R113A_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.108117 (rank : 205)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	66
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

R113B_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.128031 (rank : 170)
Query Neighborhood Hits	155	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RAD18_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.163509 (rank : 147)
Query Neighborhood Hits	155	Target Neighborhood Hits	284	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAD18_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.165544 (rank : 146)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAG1_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.089671 (rank : 222)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	68
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.092429 (rank : 220)
Query Neighborhood Hits	155	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RAPSN_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.054037 (rank : 295)
Query Neighborhood Hits	155	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

RBBP6_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.065562 (rank : 265)
Query Neighborhood Hits	155	Target Neighborhood Hits	1135	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.074516 (rank : 240)
Query Neighborhood Hits	155	Target Neighborhood Hits	1014	Shared Neighborhood Hits	68
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RFPL1_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.123367 (rank : 174)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.124030 (rank : 173)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.128707 (rank : 169)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RFWD2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.118451 (rank : 186)
Query Neighborhood Hits	155	Target Neighborhood Hits	518	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.118089 (rank : 187)
Query Neighborhood Hits	155	Target Neighborhood Hits	535	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RING1_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.158567 (rank : 150)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.155508 (rank : 154)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	76
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.144340 (rank : 159)
Query Neighborhood Hits	155	Target Neighborhood Hits	201	Shared Neighborhood Hits	74
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.144864 (rank : 158)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RN122_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.058987 (rank : 283)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN122_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.052882 (rank : 298)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

RN125_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.174586 (rank : 138)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	87
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN125_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.176458 (rank : 137)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN141_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.151948 (rank : 156)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.153623 (rank : 155)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.169246 (rank : 144)
Query Neighborhood Hits	155	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.167955 (rank : 145)
Query Neighborhood Hits	155	Target Neighborhood Hits	161	Shared Neighborhood Hits	71
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN166_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.192580 (rank : 129)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	89
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.190035 (rank : 131)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	91
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN167_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.059617 (rank : 280)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN167_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.060483 (rank : 277)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN169_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.145680 (rank : 157)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN185_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.109896 (rank : 202)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.109447 (rank : 203)
Query Neighborhood Hits	155	Target Neighborhood Hits	211	Shared Neighborhood Hits	70
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF13_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.056719 (rank : 286)
Query Neighborhood Hits	155	Target Neighborhood Hits	147	Shared Neighborhood Hits	23
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RNF13_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.061396 (rank : 273)
Query Neighborhood Hits	155	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RNF19_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.055488 (rank : 289)
Query Neighborhood Hits	155	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.055289 (rank : 290)
Query Neighborhood Hits	155	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF26_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.075128 (rank : 238)
Query Neighborhood Hits	155	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

RNF41_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.129668 (rank : 166)
Query Neighborhood Hits	155	Target Neighborhood Hits	226	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.128788 (rank : 168)
Query Neighborhood Hits	155	Target Neighborhood Hits	224	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF4_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.083105 (rank : 227)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.082027 (rank : 228)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RNF5_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.113900 (rank : 193)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.112271 (rank : 197)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF8_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.156169 (rank : 153)
Query Neighborhood Hits	155	Target Neighborhood Hits	622	Shared Neighborhood Hits	100
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.161343 (rank : 148)
Query Neighborhood Hits	155	Target Neighborhood Hits	618	Shared Neighborhood Hits	106
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

RO52_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.240051 (rank : 113)
Query Neighborhood Hits	155	Target Neighborhood Hits	360	Shared Neighborhood Hits	111
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

RSF1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.059955 (rank : 279)
Query Neighborhood Hits	155	Target Neighborhood Hits	539	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SMRA3_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.106145 (rank : 206)
Query Neighborhood Hits	155	Target Neighborhood Hits	265	Shared Neighborhood Hits	85
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.099980 (rank : 211)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SP110_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.131585 (rank : 163)
Query Neighborhood Hits	155	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

SPRY4_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.181762 (rank : 134)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

SPRY4_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.189532 (rank : 132)
Query Neighborhood Hits	155	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

TAF1L_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.056286 (rank : 287)
Query Neighborhood Hits	155	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TAF1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.060218 (rank : 278)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

TOPRS_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.090551 (rank : 221)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.093168 (rank : 216)
Query Neighborhood Hits	155	Target Neighborhood Hits	263	Shared Neighborhood Hits	49
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.072352 (rank : 249)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	75
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

TRAF2_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.065661 (rank : 264)
Query Neighborhood Hits	155	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF3_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.055938 (rank : 288)
Query Neighborhood Hits	155	Target Neighborhood Hits	463	Shared Neighborhood Hits	75
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRAF3_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.057800 (rank : 285)
Query Neighborhood Hits	155	Target Neighborhood Hits	476	Shared Neighborhood Hits	77
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

TRAF4_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.081393 (rank : 229)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF5_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.073758 (rank : 243)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	74
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF6_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.122017 (rank : 178)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI11_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.253076 (rank : 109)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	105
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.254201 (rank : 108)
Query Neighborhood Hits	155	Target Neighborhood Hits	329	Shared Neighborhood Hits	109
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI35_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.268975 (rank : 97)
Query Neighborhood Hits	155	Target Neighborhood Hits	382	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI35_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.291887 (rank : 67)
Query Neighborhood Hits	155	Target Neighborhood Hits	465	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI38_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.252127 (rank : 110)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	114
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI39_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.276814 (rank : 87)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI43_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.244595 (rank : 112)
Query Neighborhood Hits	155	Target Neighborhood Hits	341	Shared Neighborhood Hits	105
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI44_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.217639 (rank : 118)
Query Neighborhood Hits	155	Target Neighborhood Hits	393	Shared Neighborhood Hits	79
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.219820 (rank : 117)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI48_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.203731 (rank : 122)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI60_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.256344 (rank : 107)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.293256 (rank : 66)
Query Neighborhood Hits	155	Target Neighborhood Hits	584	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI62_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.291480 (rank : 68)
Query Neighborhood Hits	155	Target Neighborhood Hits	478	Shared Neighborhood Hits	112
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

UB7I3_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.054207 (rank : 294)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UHRF1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.141065 (rank : 160)
Query Neighborhood Hits	155	Target Neighborhood Hits	272	Shared Neighborhood Hits	92
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.130990 (rank : 165)
Query Neighborhood Hits	155	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

UHRF2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.158871 (rank : 149)
Query Neighborhood Hits	155	Target Neighborhood Hits	269	Shared Neighborhood Hits	92
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

UHRF2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.158310 (rank : 151)
Query Neighborhood Hits	155	Target Neighborhood Hits	275	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

ZMY11_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.071361 (rank : 253)
Query Neighborhood Hits	155	Target Neighborhood Hits	201	Shared Neighborhood Hits	9
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.072219 (rank : 250)
Query Neighborhood Hits	155	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

ZN179_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.225333 (rank : 115)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZSWM2_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.060978 (rank : 276)
Query Neighborhood Hits	155	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

ZSWM2_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.077143 (rank : 234)
Query Neighborhood Hits	155	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

Hits sorted by NC score

TRI45_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI45_MOUSE
NC score	0.990801 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	121
SwissProt Accessions	Q6PFY8, Q8BVT5	Gene names	Trim45
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45.

TRI56_MOUSE
NC score	0.771334 (rank : 3)	θ value	1.73987e-27 (rank : 10)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	112
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI56_HUMAN
NC score	0.744478 (rank : 4)	θ value	9.54697e-26 (rank : 12)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	109
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRIM3_MOUSE
NC score	0.736556 (rank : 5)	θ value	3.16345e-37 (rank : 5)
Query Neighborhood Hits	155	Target Neighborhood Hits	351	Shared Neighborhood Hits	119
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRIM3_HUMAN
NC score	0.734423 (rank : 6)	θ value	1.42001e-37 (rank : 3)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	122
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM2_HUMAN
NC score	0.731942 (rank : 7)	θ value	7.04741e-37 (rank : 6)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRIM2_MOUSE
NC score	0.731136 (rank : 8)	θ value	2.42216e-37 (rank : 4)
Query Neighborhood Hits	155	Target Neighborhood Hits	331	Shared Neighborhood Hits	119
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TIF1B_HUMAN
NC score	0.708111 (rank : 9)	θ value	3.51386e-20 (rank : 13)
Query Neighborhood Hits	155	Target Neighborhood Hits	312	Shared Neighborhood Hits	92
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.704826 (rank : 10)	θ value	4.58923e-20 (rank : 14)
Query Neighborhood Hits	155	Target Neighborhood Hits	276	Shared Neighborhood Hits	91
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

TIF1G_HUMAN
NC score	0.683546 (rank : 11)	θ value	3.06405e-32 (rank : 7)
Query Neighborhood Hits	155	Target Neighborhood Hits	410	Shared Neighborhood Hits	102
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
NC score	0.675014 (rank : 12)	θ value	4.00176e-32 (rank : 8)
Query Neighborhood Hits	155	Target Neighborhood Hits	498	Shared Neighborhood Hits	101
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI36_HUMAN
NC score	0.673145 (rank : 13)	θ value	2.97466e-19 (rank : 15)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	111
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
NC score	0.666653 (rank : 14)	θ value	1.63225e-17 (rank : 16)
Query Neighborhood Hits	155	Target Neighborhood Hits	266	Shared Neighborhood Hits	111
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI42_HUMAN
NC score	0.640828 (rank : 15)	θ value	1.29331e-14 (rank : 20)
Query Neighborhood Hits	155	Target Neighborhood Hits	283	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI42_MOUSE
NC score	0.637897 (rank : 16)	θ value	9.90251e-15 (rank : 19)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	98
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TIF1A_HUMAN
NC score	0.632327 (rank : 17)	θ value	3.17079e-29 (rank : 9)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	88
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TRIM1_HUMAN
NC score	0.631649 (rank : 18)	θ value	4.02038e-16 (rank : 18)
Query Neighborhood Hits	155	Target Neighborhood Hits	345	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.629705 (rank : 19)	θ value	3.07829e-16 (rank : 17)
Query Neighborhood Hits	155	Target Neighborhood Hits	361	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRI46_MOUSE
NC score	0.623894 (rank : 20)	θ value	7.09661e-13 (rank : 22)
Query Neighborhood Hits	155	Target Neighborhood Hits	287	Shared Neighborhood Hits	115
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_HUMAN
NC score	0.623563 (rank : 21)	θ value	5.43371e-13 (rank : 21)
Query Neighborhood Hits	155	Target Neighborhood Hits	291	Shared Neighborhood Hits	116
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TIF1A_MOUSE
NC score	0.615665 (rank : 22)	θ value	5.06226e-27 (rank : 11)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	86
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

PML_MOUSE
NC score	0.604100 (rank : 23)	θ value	6.64225e-11 (rank : 26)
Query Neighborhood Hits	155	Target Neighborhood Hits	246	Shared Neighborhood Hits	95
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI18_MOUSE
NC score	0.602443 (rank : 24)	θ value	2.28291e-11 (rank : 25)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	116
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI18_HUMAN
NC score	0.595730 (rank : 25)	θ value	7.84624e-12 (rank : 24)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	115
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

PML_HUMAN
NC score	0.593797 (rank : 26)	θ value	6.00763e-12 (rank : 23)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	89
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

TRIM9_HUMAN
NC score	0.562266 (rank : 27)	θ value	5.26297e-08 (rank : 33)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	110
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRI54_MOUSE
NC score	0.556794 (rank : 28)	θ value	1.43324e-05 (rank : 40)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	104
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_HUMAN
NC score	0.552099 (rank : 29)	θ value	3.19293e-05 (rank : 44)
Query Neighborhood Hits	155	Target Neighborhood Hits	209	Shared Neighborhood Hits	105
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM9_MOUSE
NC score	0.545377 (rank : 30)	θ value	3.08544e-08 (rank : 32)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	110
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

TRI63_HUMAN
NC score	0.544911 (rank : 31)	θ value	0.00020696 (rank : 50)
Query Neighborhood Hits	155	Target Neighborhood Hits	298	Shared Neighborhood Hits	111
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
NC score	0.540057 (rank : 32)	θ value	0.000602161 (rank : 54)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	108
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI55_HUMAN
NC score	0.538050 (rank : 33)	θ value	0.000158464 (rank : 47)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRIM8_MOUSE
NC score	0.506521 (rank : 34)	θ value	1.38499e-08 (rank : 30)
Query Neighborhood Hits	155	Target Neighborhood Hits	674	Shared Neighborhood Hits	124
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.505447 (rank : 35)	θ value	4.76016e-09 (rank : 29)
Query Neighborhood Hits	155	Target Neighborhood Hits	650	Shared Neighborhood Hits	125
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRI59_HUMAN
NC score	0.504968 (rank : 36)	θ value	6.43352e-06 (rank : 39)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI59_MOUSE
NC score	0.494795 (rank : 37)	θ value	2.44474e-05 (rank : 42)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	114
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI13_HUMAN
NC score	0.463962 (rank : 38)	θ value	2.44474e-05 (rank : 41)
Query Neighborhood Hits	155	Target Neighborhood Hits	274	Shared Neighborhood Hits	119
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI66_MOUSE
NC score	0.460981 (rank : 39)	θ value	1.25267e-09 (rank : 28)
Query Neighborhood Hits	155	Target Neighborhood Hits	491	Shared Neighborhood Hits	64
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI13_MOUSE
NC score	0.459993 (rank : 40)	θ value	0.000121331 (rank : 45)
Query Neighborhood Hits	155	Target Neighborhood Hits	282	Shared Neighborhood Hits	119
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI66_HUMAN
NC score	0.457968 (rank : 41)	θ value	1.133e-10 (rank : 27)
Query Neighborhood Hits	155	Target Neighborhood Hits	479	Shared Neighborhood Hits	61
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI32_HUMAN
NC score	0.455590 (rank : 42)	θ value	0.000786445 (rank : 55)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	112
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.451111 (rank : 43)	θ value	0.00102713 (rank : 57)
Query Neighborhood Hits	155	Target Neighborhood Hits	271	Shared Neighborhood Hits	111
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI47_HUMAN
NC score	0.451015 (rank : 44)	θ value	0.00020696 (rank : 49)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	113
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
NC score	0.449786 (rank : 45)	θ value	2.88788e-06 (rank : 38)
Query Neighborhood Hits	155	Target Neighborhood Hits	295	Shared Neighborhood Hits	112
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI29_MOUSE
NC score	0.448186 (rank : 46)	θ value	0.00035302 (rank : 51)
Query Neighborhood Hits	155	Target Neighborhood Hits	306	Shared Neighborhood Hits	84
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI29_HUMAN
NC score	0.442411 (rank : 47)	θ value	0.000602161 (rank : 53)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	78
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI25_MOUSE
NC score	0.428885 (rank : 48)	θ value	0.00102713 (rank : 56)
Query Neighborhood Hits	155	Target Neighborhood Hits	446	Shared Neighborhood Hits	120
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI25_HUMAN
NC score	0.420578 (rank : 49)	θ value	0.0113563 (rank : 61)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	121
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI16_MOUSE
NC score	0.378942 (rank : 50)	θ value	0.000158464 (rank : 46)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	79
SwissProt Accessions	Q99PP9, Q7TPY6, Q8C332, Q8C6V0	Gene names	Trim16, Ebbp
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI74_HUMAN
NC score	0.370919 (rank : 51)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	155	Target Neighborhood Hits	249	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI73_HUMAN
NC score	0.368567 (rank : 52)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	155	Target Neighborhood Hits	258	Shared Neighborhood Hits	116
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI37_HUMAN
NC score	0.367465 (rank : 53)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	98
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
NC score	0.367201 (rank : 54)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	98
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI65_HUMAN
NC score	0.362977 (rank : 55)	θ value	0.125558 (rank : 78)
Query Neighborhood Hits	155	Target Neighborhood Hits	330	Shared Neighborhood Hits	111
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI31_HUMAN
NC score	0.346388 (rank : 56)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	155	Target Neighborhood Hits	299	Shared Neighborhood Hits	115
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI65_MOUSE
NC score	0.340869 (rank : 57)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	155	Target Neighborhood Hits	340	Shared Neighborhood Hits	109
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI50_MOUSE
NC score	0.333941 (rank : 58)	θ value	0.0148317 (rank : 63)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	119
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI50_HUMAN
NC score	0.329694 (rank : 59)	θ value	0.0563607 (rank : 71)
Query Neighborhood Hits	155	Target Neighborhood Hits	294	Shared Neighborhood Hits	118
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI16_HUMAN
NC score	0.321233 (rank : 60)	θ value	0.000461057 (rank : 52)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	78
SwissProt Accessions	O95361, Q7Z6I2, Q96BE8, Q96J43	Gene names	TRIM16, EBBP
Domain Architecture
Description	Tripartite motif-containing protein 16 (Estrogen-responsive B box protein).

TRI14_MOUSE
NC score	0.312472 (rank : 61)	θ value	0.0431538 (rank : 66)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI14_HUMAN
NC score	0.309534 (rank : 62)	θ value	0.125558 (rank : 77)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	87
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI12_MOUSE
NC score	0.302885 (rank : 63)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	155	Target Neighborhood Hits	387	Shared Neighborhood Hits	112
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI40_HUMAN
NC score	0.296782 (rank : 64)	θ value	1.06291 (rank : 95)
Query Neighborhood Hits	155	Target Neighborhood Hits	279	Shared Neighborhood Hits	104
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI41_HUMAN
NC score	0.294770 (rank : 65)	θ value	0.00665767 (rank : 60)
Query Neighborhood Hits	155	Target Neighborhood Hits	349	Shared Neighborhood Hits	113
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI62_HUMAN
NC score	0.293256 (rank : 66)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	155	Target Neighborhood Hits	584	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI35_MOUSE
NC score	0.291887 (rank : 67)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	155	Target Neighborhood Hits	465	Shared Neighborhood Hits	115
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI62_MOUSE
NC score	0.291480 (rank : 68)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	155	Target Neighborhood Hits	478	Shared Neighborhood Hits	112
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM7_MOUSE
NC score	0.290785 (rank : 69)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	118
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

RN183_HUMAN
NC score	0.290429 (rank : 70)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	77
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI10_MOUSE
NC score	0.289333 (rank : 71)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	155	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI34_HUMAN
NC score	0.288138 (rank : 72)	θ value	0.0113563 (rank : 62)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI30_MOUSE
NC score	0.287471 (rank : 73)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	155	Target Neighborhood Hits	434	Shared Neighborhood Hits	118
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRIM5_HUMAN
NC score	0.285172 (rank : 74)	θ value	0.21417 (rank : 81)
Query Neighborhood Hits	155	Target Neighborhood Hits	424	Shared Neighborhood Hits	119
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

ARD1_MOUSE
NC score	0.285083 (rank : 75)	θ value	3.19293e-05 (rank : 43)
Query Neighborhood Hits	155	Target Neighborhood Hits	573	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGX0, Q8C2B6, Q8CDA4, Q8CDA7	Gene names	Trim23, Arfd1
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23).

TRI22_HUMAN
NC score	0.283817 (rank : 76)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	117
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

ZN313_MOUSE
NC score	0.283650 (rank : 77)	θ value	0.0563607 (rank : 72)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	100
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

TRI10_HUMAN
NC score	0.282573 (rank : 78)	θ value	2.36792 (rank : 115)
Query Neighborhood Hits	155	Target Neighborhood Hits	315	Shared Neighborhood Hits	114
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI15_HUMAN
NC score	0.280386 (rank : 79)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	155	Target Neighborhood Hits	395	Shared Neighborhood Hits	116
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI17_MOUSE
NC score	0.279945 (rank : 80)	θ value	0.0961366 (rank : 74)
Query Neighborhood Hits	155	Target Neighborhood Hits	620	Shared Neighborhood Hits	112
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI27_HUMAN
NC score	0.279520 (rank : 81)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	155	Target Neighborhood Hits	273	Shared Neighborhood Hits	111
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI39_MOUSE
NC score	0.278994 (rank : 82)	θ value	0.0563607 (rank : 70)
Query Neighborhood Hits	155	Target Neighborhood Hits	691	Shared Neighborhood Hits	118
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM6_HUMAN
NC score	0.278483 (rank : 83)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	155	Target Neighborhood Hits	412	Shared Neighborhood Hits	118
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI27_MOUSE
NC score	0.277841 (rank : 84)	θ value	0.0961366 (rank : 75)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	109
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI52_HUMAN
NC score	0.277607 (rank : 85)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	103
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

MEFV_MOUSE
NC score	0.277380 (rank : 86)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	155	Target Neighborhood Hits	236	Shared Neighborhood Hits	86
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRI39_HUMAN
NC score	0.276814 (rank : 87)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	118
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRIM6_MOUSE
NC score	0.276012 (rank : 88)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	155	Target Neighborhood Hits	451	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

ZN313_HUMAN
NC score	0.275792 (rank : 89)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRIM7_HUMAN
NC score	0.274675 (rank : 90)	θ value	1.81305 (rank : 110)
Query Neighborhood Hits	155	Target Neighborhood Hits	336	Shared Neighborhood Hits	112
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM4_HUMAN
NC score	0.273680 (rank : 91)	θ value	3.0926 (rank : 122)
Query Neighborhood Hits	155	Target Neighborhood Hits	321	Shared Neighborhood Hits	111
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI68_MOUSE
NC score	0.273678 (rank : 92)	θ value	0.0431538 (rank : 67)
Query Neighborhood Hits	155	Target Neighborhood Hits	356	Shared Neighborhood Hits	122
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI26_HUMAN
NC score	0.273372 (rank : 93)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	155	Target Neighborhood Hits	335	Shared Neighborhood Hits	108
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

RN183_MOUSE
NC score	0.273295 (rank : 94)	θ value	2.36792 (rank : 114)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	72
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

ARD1_HUMAN
NC score	0.270579 (rank : 95)	θ value	0.00020696 (rank : 48)
Query Neighborhood Hits	155	Target Neighborhood Hits	621	Shared Neighborhood Hits	82
SwissProt Accessions	P36406, Q9BZY4, Q9BZY5	Gene names	TRIM23, ARD1, ARFD1, RNF46
Domain Architecture
Description	GTP-binding protein ARD-1 (ADP-ribosylation factor domain protein 1) (Tripartite motif-containing protein 23) (RING finger protein 46).

RNF39_HUMAN
NC score	0.270088 (rank : 96)	θ value	0.163984 (rank : 79)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	102
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

TRI35_HUMAN
NC score	0.268975 (rank : 97)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	155	Target Neighborhood Hits	382	Shared Neighborhood Hits	112
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

RN168_HUMAN
NC score	0.268800 (rank : 98)	θ value	1.38821 (rank : 99)
Query Neighborhood Hits	155	Target Neighborhood Hits	370	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI17_HUMAN
NC score	0.268447 (rank : 99)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	155	Target Neighborhood Hits	318	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

RN168_MOUSE
NC score	0.264574 (rank : 100)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	155	Target Neighborhood Hits	440	Shared Neighborhood Hits	99
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI26_MOUSE
NC score	0.264242 (rank : 101)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	155	Target Neighborhood Hits	339	Shared Neighborhood Hits	107
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

RO52_HUMAN
NC score	0.263433 (rank : 102)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	155	Target Neighborhood Hits	419	Shared Neighborhood Hits	121
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI60_HUMAN
NC score	0.262432 (rank : 103)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	155	Target Neighborhood Hits	357	Shared Neighborhood Hits	109
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

RN152_MOUSE
NC score	0.261869 (rank : 104)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	155	Target Neighborhood Hits	109	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN152_HUMAN
NC score	0.260628 (rank : 105)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	155	Target Neighborhood Hits	107	Shared Neighborhood Hits	57
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

TRI68_HUMAN
NC score	0.257028 (rank : 106)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	114
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

TRI60_MOUSE
NC score	0.256344 (rank : 107)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI11_MOUSE
NC score	0.254201 (rank : 108)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	155	Target Neighborhood Hits	329	Shared Neighborhood Hits	109
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI11_HUMAN
NC score	0.253076 (rank : 109)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	155	Target Neighborhood Hits	316	Shared Neighborhood Hits	105
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI38_HUMAN
NC score	0.252127 (rank : 110)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	114
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI34_MOUSE
NC score	0.251830 (rank : 111)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	155	Target Neighborhood Hits	332	Shared Neighborhood Hits	106
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI43_HUMAN
NC score	0.244595 (rank : 112)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	155	Target Neighborhood Hits	341	Shared Neighborhood Hits	105
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

RO52_MOUSE
NC score	0.240051 (rank : 113)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	155	Target Neighborhood Hits	360	Shared Neighborhood Hits	111
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

NHLC1_MOUSE
NC score	0.228421 (rank : 114)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	155	Target Neighborhood Hits	103	Shared Neighborhood Hits	53
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

ZN179_HUMAN
NC score	0.225333 (rank : 115)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

FSD1L_MOUSE
NC score	0.223138 (rank : 116)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	155	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BYN5, Q3USW7	Gene names	Fsd1l, Ccdc10, Csdufd1, Fsd1nl
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

TRI44_MOUSE
NC score	0.219820 (rank : 117)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	155	Target Neighborhood Hits	327	Shared Neighborhood Hits	73
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI44_HUMAN
NC score	0.217639 (rank : 118)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	155	Target Neighborhood Hits	393	Shared Neighborhood Hits	79
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI49_HUMAN
NC score	0.208712 (rank : 119)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	104
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

MEFV_HUMAN
NC score	0.206178 (rank : 120)	θ value	1.38821 (rank : 97)
Query Neighborhood Hits	155	Target Neighborhood Hits	431	Shared Neighborhood Hits	91
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

NHLC1_HUMAN
NC score	0.204100 (rank : 121)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	155	Target Neighborhood Hits	91	Shared Neighborhood Hits	48
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRI48_HUMAN
NC score	0.203731 (rank : 122)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	97
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

FLNC_HUMAN
NC score	0.202938 (rank : 123)	θ value	3.08544e-08 (rank : 31)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	Q14315, O95303, Q07985, Q9NS12, Q9NYE5, Q9UMR8, Q9Y503	Gene names	FLNC, ABPL, FLN2
Domain Architecture
Description	Filamin-C (Gamma-filamin) (Filamin-2) (Protein FLNc) (Actin-binding- like protein) (ABP-L) (ABP-280-like protein).

FLNA_MOUSE
NC score	0.200112 (rank : 124)	θ value	5.81887e-07 (rank : 35)
Query Neighborhood Hits	155	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BTM8, O54934, Q7TQI1, Q8BLK1, Q8BTN7, Q8VHX5, Q8VHX8, Q99KQ2	Gene names	Flna, Fln, Fln1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNA_HUMAN
NC score	0.200093 (rank : 125)	θ value	5.81887e-07 (rank : 34)
Query Neighborhood Hits	155	Target Neighborhood Hits	138	Shared Neighborhood Hits	13
SwissProt Accessions	P21333	Gene names	FLNA, FLN, FLN1
Domain Architecture
Description	Filamin-A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) (ABP-280) (Nonmuscle filamin).

FLNB_MOUSE
NC score	0.195376 (rank : 126)	θ value	1.69304e-06 (rank : 36)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	14
SwissProt Accessions	Q80X90, Q8VHX4, Q8VHX7, Q99KY3	Gene names	Flnb
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (ABP- 280-like protein).

FLNB_HUMAN
NC score	0.194577 (rank : 127)	θ value	2.88788e-06 (rank : 37)
Query Neighborhood Hits	155	Target Neighborhood Hits	111	Shared Neighborhood Hits	13
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

BRCA1_HUMAN
NC score	0.193849 (rank : 128)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	155	Target Neighborhood Hits	381	Shared Neighborhood Hits	93
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

RN166_HUMAN
NC score	0.192580 (rank : 129)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	155	Target Neighborhood Hits	240	Shared Neighborhood Hits	89
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

BRCA1_MOUSE
NC score	0.192290 (rank : 130)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	155	Target Neighborhood Hits	436	Shared Neighborhood Hits	93
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

RN166_MOUSE
NC score	0.190035 (rank : 131)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	155	Target Neighborhood Hits	248	Shared Neighborhood Hits	91
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

SPRY4_MOUSE
NC score	0.189532 (rank : 132)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	155	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	Q91WK1, Q8BUS6, Q9D651	Gene names	Spryd4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

FSD1L_HUMAN
NC score	0.183240 (rank : 133)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	155	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BXM9, Q5T880	Gene names	FSD1L, CCDC10, CSDUFD1, FSD1NL
Domain Architecture	No domain graphic available
Description	FSD1-like protein (FSD1 N-terminal-like protein) (Coiled-coil domain- containing protein 10).

SPRY4_HUMAN
NC score	0.181762 (rank : 134)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	155	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WW59	Gene names	SPRYD4
Domain Architecture	No domain graphic available
Description	SPRY domain-containing protein 4.

PEX10_HUMAN
NC score	0.179428 (rank : 135)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	77
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

BSPRY_HUMAN
NC score	0.176534 (rank : 136)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	155	Target Neighborhood Hits	115	Shared Neighborhood Hits	60
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RN125_MOUSE
NC score	0.176458 (rank : 137)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	80
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

RN125_HUMAN
NC score	0.174586 (rank : 138)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	87
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

LY10_HUMAN
NC score	0.172399 (rank : 139)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	155	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

BFAR_HUMAN
NC score	0.170162 (rank : 140)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	155	Target Neighborhood Hits	222	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

BSPRY_MOUSE
NC score	0.170100 (rank : 141)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	67
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

CHFR_HUMAN
NC score	0.169937 (rank : 142)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	82
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
NC score	0.169936 (rank : 143)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	155	Target Neighborhood Hits	264	Shared Neighborhood Hits	80
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN146_HUMAN
NC score	0.169246 (rank : 144)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	155	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
NC score	0.167955 (rank : 145)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	155	Target Neighborhood Hits	161	Shared Neighborhood Hits	71
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RAD18_MOUSE
NC score	0.165544 (rank : 146)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	155	Target Neighborhood Hits	230	Shared Neighborhood Hits	79
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RAD18_HUMAN
NC score	0.163509 (rank : 147)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	155	Target Neighborhood Hits	284	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RNF8_MOUSE
NC score	0.161343 (rank : 148)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	155	Target Neighborhood Hits	618	Shared Neighborhood Hits	106
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

UHRF2_HUMAN
NC score	0.158871 (rank : 149)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	155	Target Neighborhood Hits	269	Shared Neighborhood Hits	92
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

RING1_HUMAN
NC score	0.158567 (rank : 150)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

UHRF2_MOUSE
NC score	0.158310 (rank : 151)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	155	Target Neighborhood Hits	275	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TMI3, Q8BG56, Q8BJP6, Q8BY30, Q8K1I5	Gene names	Uhrf2, Nirf
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95-like ring finger protein) (Nuclear zinc finger protein Np97) (NIRF).

BFAR_MOUSE
NC score	0.157969 (rank : 152)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	155	Target Neighborhood Hits	232	Shared Neighborhood Hits	76
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

RNF8_HUMAN
NC score	0.156169 (rank : 153)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	155	Target Neighborhood Hits	622	Shared Neighborhood Hits	100
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RING1_MOUSE
NC score	0.155508 (rank : 154)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	155	Target Neighborhood Hits	220	Shared Neighborhood Hits	76
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RN141_MOUSE
NC score	0.153623 (rank : 155)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	155	Target Neighborhood Hits	200	Shared Neighborhood Hits	76
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_HUMAN
NC score	0.151948 (rank : 156)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN169_HUMAN
NC score	0.145680 (rank : 157)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RING2_MOUSE
NC score	0.144864 (rank : 158)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	155	Target Neighborhood Hits	199	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.144340 (rank : 159)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	155	Target Neighborhood Hits	201	Shared Neighborhood Hits	74
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

UHRF1_HUMAN
NC score	0.141065 (rank : 160)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	155	Target Neighborhood Hits	272	Shared Neighborhood Hits	92
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

AIRE_MOUSE
NC score	0.136039 (rank : 161)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.135423 (rank : 162)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	155	Target Neighborhood Hits	144	Shared Neighborhood Hits	8
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

SP110_HUMAN
NC score	0.131585 (rank : 163)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	155	Target Neighborhood Hits	141	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TRAF6_MOUSE
NC score	0.131323 (rank : 164)	θ value	0.163984 (rank : 80)
Query Neighborhood Hits	155	Target Neighborhood Hits	255	Shared Neighborhood Hits	86
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

UHRF1_MOUSE
NC score	0.130990 (rank : 165)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	155	Target Neighborhood Hits	278	Shared Neighborhood Hits	91
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

RNF41_HUMAN
NC score	0.129668 (rank : 166)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	155	Target Neighborhood Hits	226	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

ERMAP_HUMAN
NC score	0.129340 (rank : 167)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	155	Target Neighborhood Hits	155	Shared Neighborhood Hits	49
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

RNF41_MOUSE
NC score	0.128788 (rank : 168)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	155	Target Neighborhood Hits	224	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RFPL3_HUMAN
NC score	0.128707 (rank : 169)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	77
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

R113B_HUMAN
NC score	0.128031 (rank : 170)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	155	Target Neighborhood Hits	165	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

RC3H1_MOUSE
NC score	0.127813 (rank : 171)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	155	Target Neighborhood Hits	244	Shared Neighborhood Hits	93
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

K0157_HUMAN
NC score	0.125326 (rank : 172)	θ value	0.00298849 (rank : 58)
Query Neighborhood Hits	155	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

RFPL2_HUMAN
NC score	0.124030 (rank : 173)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	155	Target Neighborhood Hits	126	Shared Neighborhood Hits	76
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL1_HUMAN
NC score	0.123367 (rank : 174)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	155	Target Neighborhood Hits	119	Shared Neighborhood Hits	69
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

BT1A1_HUMAN
NC score	0.122991 (rank : 175)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	155	Target Neighborhood Hits	322	Shared Neighborhood Hits	51
SwissProt Accessions	Q13410, Q9H458	Gene names	BTN1A1, BTN
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

BT1A1_MOUSE
NC score	0.122741 (rank : 176)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	155	Target Neighborhood Hits	252	Shared Neighborhood Hits	51
SwissProt Accessions	Q62556, P97392, Q8K2H7, Q921K7	Gene names	Btn1a1, Btn
Domain Architecture
Description	Butyrophilin subfamily 1 member A1 precursor (BT).

K0157_MOUSE
NC score	0.122610 (rank : 177)	θ value	0.00390308 (rank : 59)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	Q3TCJ1, Q3TB08, Q8K0R4	Gene names	Kiaa0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

TRAF6_HUMAN
NC score	0.122017 (rank : 178)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

LNX2_MOUSE
NC score	0.121561 (rank : 179)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	155	Target Neighborhood Hits	407	Shared Neighborhood Hits	87
SwissProt Accessions	Q91XL2, Q8CBE1	Gene names	Lnx2
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2).

LNX2_HUMAN
NC score	0.121180 (rank : 180)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	155	Target Neighborhood Hits	389	Shared Neighborhood Hits	88
SwissProt Accessions	Q8N448, Q5W0P0, Q6ZMH2, Q96SH4	Gene names	LNX2, PDZRN1
Domain Architecture
Description	Ligand of Numb-protein X 2 (Numb-binding protein 2) (PDZ domain- containing RING finger protein 1).

RC3H1_HUMAN
NC score	0.120543 (rank : 181)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	155	Target Neighborhood Hits	433	Shared Neighborhood Hits	93
SwissProt Accessions	Q5TC82, Q5W180, Q5W181, Q8IVE6, Q8N9V1	Gene names	RC3H1, KIAA2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1).

DTX3_MOUSE
NC score	0.120161 (rank : 182)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	155	Target Neighborhood Hits	202	Shared Neighborhood Hits	75
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

MNAB_HUMAN
NC score	0.120003 (rank : 183)	θ value	1.81305 (rank : 103)
Query Neighborhood Hits	155	Target Neighborhood Hits	196	Shared Neighborhood Hits	82
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
NC score	0.119927 (rank : 184)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	84
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

ERMAP_MOUSE
NC score	0.118721 (rank : 185)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	155	Target Neighborhood Hits	231	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLN5, Q3UV82, Q6P4T5, Q8CEH1	Gene names	Ermap
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor.

RFWD2_HUMAN
NC score	0.118451 (rank : 186)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	155	Target Neighborhood Hits	518	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.118089 (rank : 187)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	155	Target Neighborhood Hits	535	Shared Neighborhood Hits	87
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

DTX3_HUMAN
NC score	0.118010 (rank : 188)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	155	Target Neighborhood Hits	198	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

BT3A3_HUMAN
NC score	0.117032 (rank : 189)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	155	Target Neighborhood Hits	233	Shared Neighborhood Hits	49
SwissProt Accessions	O00478	Gene names	BTN3A3, BTF3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A3 precursor.

BT3A1_HUMAN
NC score	0.116593 (rank : 190)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	155	Target Neighborhood Hits	229	Shared Neighborhood Hits	50
SwissProt Accessions	O00481, Q99420, Q9HCY1	Gene names	BTN3A1, BTF5
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A1 precursor (CD277 antigen).

PKCB1_HUMAN
NC score	0.115181 (rank : 191)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	155	Target Neighborhood Hits	488	Shared Neighborhood Hits	14
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

LNX1_MOUSE
NC score	0.114813 (rank : 192)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	155	Target Neighborhood Hits	377	Shared Neighborhood Hits	81
SwissProt Accessions	O70263, O70264, Q8BRI8, Q8CFR3	Gene names	Lnx1, Lnx
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-binding protein 1) (Ligand of Numb-protein X 1).

RNF5_HUMAN
NC score	0.113900 (rank : 193)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	66
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

BT2A2_HUMAN
NC score	0.113611 (rank : 194)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	155	Target Neighborhood Hits	191	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WVV5, O00480	Gene names	BTN2A2, BT2.2, BTF2
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A2 precursor.

BTNL3_HUMAN
NC score	0.112677 (rank : 195)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	155	Target Neighborhood Hits	143	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UXE8, Q9Y2C7	Gene names	BTNL3, BTNLR, COLF4100
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 3 precursor (Butyrophilin-like receptor).

BTNL9_HUMAN
NC score	0.112528 (rank : 196)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	155	Target Neighborhood Hits	125	Shared Neighborhood Hits	46
SwissProt Accessions	Q6UXG8, Q6P660, Q96DM5	Gene names	BTNL9
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 9 precursor.

RNF5_MOUSE
NC score	0.112271 (rank : 197)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	155	Target Neighborhood Hits	206	Shared Neighborhood Hits	64
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

BAZ2A_HUMAN
NC score	0.112186 (rank : 198)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	155	Target Neighborhood Hits	780	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

PF21A_MOUSE
NC score	0.111797 (rank : 199)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	155	Target Neighborhood Hits	285	Shared Neighborhood Hits	12
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

LNX1_HUMAN
NC score	0.110945 (rank : 200)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	155	Target Neighborhood Hits	379	Shared Neighborhood Hits	81
SwissProt Accessions	Q8TBB1, Q8N4C2, Q96MJ7, Q9BY20	Gene names	LNX1, LNX
Domain Architecture
Description	Ubiquitin ligase LNX (EC 6.3.2.-) (Numb-binding protein 1) (Ligand of Numb-protein X 1).

PF21A_HUMAN
NC score	0.110111 (rank : 201)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	155	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

RN185_HUMAN
NC score	0.109896 (rank : 202)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	155	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.109447 (rank : 203)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	155	Target Neighborhood Hits	211	Shared Neighborhood Hits	70
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

BAZ2A_MOUSE
NC score	0.108470 (rank : 204)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	155	Target Neighborhood Hits	744	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

R113A_HUMAN
NC score	0.108117 (rank : 205)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	66
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

SMRA3_HUMAN
NC score	0.106145 (rank : 206)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	155	Target Neighborhood Hits	265	Shared Neighborhood Hits	85
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

BT2A1_HUMAN
NC score	0.104736 (rank : 207)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	48
SwissProt Accessions	Q7KYR7, O00475, P78408, Q7KYQ7, Q7Z386, Q9NU62	Gene names	BTN2A1, BT2.1, BTF1
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A1 precursor.

BIRC7_HUMAN
NC score	0.103305 (rank : 208)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	155	Target Neighborhood Hits	185	Shared Neighborhood Hits	80
SwissProt Accessions	Q96CA5, Q9BQV0, Q9H2A8, Q9HAP7	Gene names	BIRC7, KIAP, LIVIN, MLIAP
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 7 (Kidney inhibitor of apoptosis protein) (KIAP) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (Livin).

BT2A3_HUMAN
NC score	0.101711 (rank : 209)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	155	Target Neighborhood Hits	195	Shared Neighborhood Hits	46
SwissProt Accessions	Q96KV6	Gene names	BTN2A3
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 2 member A3 precursor.

BTNL8_HUMAN
NC score	0.101088 (rank : 210)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	155	Target Neighborhood Hits	177	Shared Neighborhood Hits	48
SwissProt Accessions	Q6UX41, Q9H730	Gene names	BTNL8
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 8 precursor.

SMRA3_MOUSE
NC score	0.099980 (rank : 211)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	155	Target Neighborhood Hits	267	Shared Neighborhood Hits	84
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

PHF12_HUMAN
NC score	0.098222 (rank : 212)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	155	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
NC score	0.098086 (rank : 213)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	155	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

BAZ2B_HUMAN
NC score	0.094938 (rank : 214)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	155	Target Neighborhood Hits	803	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
NC score	0.094777 (rank : 215)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	155	Target Neighborhood Hits	786	Shared Neighborhood Hits	16
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

TOPRS_MOUSE
NC score	0.093168 (rank : 216)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	155	Target Neighborhood Hits	263	Shared Neighborhood Hits	49
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRAF7_HUMAN
NC score	0.093153 (rank : 217)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	155	Target Neighborhood Hits	482	Shared Neighborhood Hits	86
SwissProt Accessions	Q6Q0C0, Q9H073	Gene names	TRAF7, RFWD1, RNF119
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7) (RING finger and WD repeat domain protein 1) (RING finger protein 119).

TRAF5_MOUSE
NC score	0.092925 (rank : 218)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	155	Target Neighborhood Hits	355	Shared Neighborhood Hits	78
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

CBLC_MOUSE
NC score	0.092438 (rank : 219)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	155	Target Neighborhood Hits	186	Shared Neighborhood Hits	53
SwissProt Accessions	Q80XL1, Q99PB6, Q9D6L2, Q9D7A9	Gene names	Cblc, Cbl3
Domain Architecture	No domain graphic available
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3).

RAG1_MOUSE
NC score	0.092429 (rank : 220)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	155	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TOPRS_HUMAN
NC score	0.090551 (rank : 221)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	155	Target Neighborhood Hits	286	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RAG1_HUMAN
NC score	0.089671 (rank : 222)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	155	Target Neighborhood Hits	203	Shared Neighborhood Hits	68
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

AMD_HUMAN
NC score	0.089384 (rank : 223)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	155	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P19021, O95080, Q16252, Q16253, Q86U53, Q8WVC7, Q9UCG0	Gene names	PAM
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

CBLC_HUMAN
NC score	0.089219 (rank : 224)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	155	Target Neighborhood Hits	173	Shared Neighborhood Hits	54
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

TRAF7_MOUSE
NC score	0.088522 (rank : 225)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	155	Target Neighborhood Hits	470	Shared Neighborhood Hits	85
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

PF21B_HUMAN
NC score	0.087145 (rank : 226)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	155	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RNF4_HUMAN
NC score	0.083105 (rank : 227)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	68
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
NC score	0.082027 (rank : 228)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	155	Target Neighborhood Hits	212	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRAF4_HUMAN
NC score	0.081393 (rank : 229)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	155	Target Neighborhood Hits	373	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

CECR2_HUMAN
NC score	0.079562 (rank : 230)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	155	Target Neighborhood Hits	543	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

BAZ1A_HUMAN
NC score	0.078387 (rank : 231)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	155	Target Neighborhood Hits	693	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BRD2_HUMAN
NC score	0.078177 (rank : 232)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	155	Target Neighborhood Hits	242	Shared Neighborhood Hits	9
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

PF21B_MOUSE
NC score	0.077372 (rank : 233)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	155	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

ZSWM2_MOUSE
NC score	0.077143 (rank : 234)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	155	Target Neighborhood Hits	132	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D9X6	Gene names	Zswim2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

CM007_MOUSE
NC score	0.076361 (rank : 235)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	155	Target Neighborhood Hits	416	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

AMFR_MOUSE
NC score	0.075540 (rank : 236)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	155	Target Neighborhood Hits	208	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R049, Q8K008, Q99LH5	Gene names	Amfr
Domain Architecture
Description	Autocrine motility factor receptor (EC 6.3.2.19) (AMF receptor).

AMFR2_HUMAN
NC score	0.075439 (rank : 237)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	155	Target Neighborhood Hits	219	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKV5, Q8IZ70	Gene names	AMFR
Domain Architecture
Description	Autocrine motility factor receptor, isoform 2 (EC 6.3.2.-) (AMF receptor) (gp78).

RNF26_HUMAN
NC score	0.075128 (rank : 238)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	155	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BY78	Gene names	RNF26
Domain Architecture	No domain graphic available
Description	RING finger protein 26.

PZRN3_MOUSE
NC score	0.074634 (rank : 239)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	155	Target Neighborhood Hits	447	Shared Neighborhood Hits	81
SwissProt Accessions	Q69ZS0, Q91Z03, Q9QY54, Q9QY55	Gene names	Pdzrn3, Kiaa1095, Semcap3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

RBBP6_MOUSE
NC score	0.074516 (rank : 240)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	155	Target Neighborhood Hits	1014	Shared Neighborhood Hits	68
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

AMD_MOUSE
NC score	0.074478 (rank : 241)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	155	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	P97467	Gene names	Pam
Domain Architecture
Description	Peptidyl-glycine alpha-amidating monooxygenase precursor (PAM) [Includes: Peptidylglycine alpha-hydroxylating monooxygenase (EC 1.14.17.3) (PHM); Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (EC 4.3.2.5) (Peptidylamidoglycolate lyase) (PAL)].

PZRN4_HUMAN
NC score	0.074295 (rank : 242)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	155	Target Neighborhood Hits	438	Shared Neighborhood Hits	87
SwissProt Accessions	Q6ZMN7, Q6N052, Q8IUU1, Q9NTP7	Gene names	PDZRN4, LNX4, SEMCAP3L
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 4 (Ligand of Numb-protein X 4) (SEMACAP3-like protein).

TRAF5_HUMAN
NC score	0.073758 (rank : 243)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	155	Target Neighborhood Hits	396	Shared Neighborhood Hits	74
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

PZRN3_HUMAN
NC score	0.073340 (rank : 244)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	155	Target Neighborhood Hits	461	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UPQ7, Q8N2N7, Q96CC2, Q9NSQ2	Gene names	PDZRN3, KIAA1095, LNX3, SEMCAP3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing RING finger protein 3 (Ligand of Numb-protein X 3) (Semaphorin cytoplasmic domain-associated protein 3) (SEMACAP3 protein).

UB7I3_MOUSE
NC score	0.073108 (rank : 245)	θ value	3.0926 (rank : 123)
Query Neighborhood Hits	155	Target Neighborhood Hits	131	Shared Neighborhood Hits	43
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

CBL_HUMAN
NC score	0.072725 (rank : 246)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	155	Target Neighborhood Hits	353	Shared Neighborhood Hits	64
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

CBLB_MOUSE
NC score	0.072711 (rank : 247)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	155	Target Neighborhood Hits	277	Shared Neighborhood Hits	65
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CBLB_HUMAN
NC score	0.072435 (rank : 248)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	64
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

TRAF2_HUMAN
NC score	0.072352 (rank : 249)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	75
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

ZMY11_MOUSE
NC score	0.072219 (rank : 250)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	155	Target Neighborhood Hits	198	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CBL_MOUSE
NC score	0.071412 (rank : 251)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	155	Target Neighborhood Hits	426	Shared Neighborhood Hits	65
SwissProt Accessions	P22682, Q8CEA1	Gene names	Cbl
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene).

NSD1_MOUSE
NC score	0.071385 (rank : 252)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	155	Target Neighborhood Hits	472	Shared Neighborhood Hits	13
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

ZMY11_HUMAN
NC score	0.071361 (rank : 253)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	155	Target Neighborhood Hits	201	Shared Neighborhood Hits	9
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

GCNL2_HUMAN
NC score	0.070870 (rank : 254)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	155	Target Neighborhood Hits	159	Shared Neighborhood Hits	7
SwissProt Accessions	Q92830, Q9UCW1	Gene names	GCN5L2, GCN5, HGCN5
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (hsGCN5) (STAF97).

BRDT_HUMAN
NC score	0.070377 (rank : 255)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	155	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	Q58F21, O14789, Q6P5T1, Q7Z4A6, Q8IWI6	Gene names	BRDT
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein).

BRDT_MOUSE
NC score	0.070216 (rank : 256)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	155	Target Neighborhood Hits	243	Shared Neighborhood Hits	9
SwissProt Accessions	Q91Y44, Q59HJ4	Gene names	Brdt, Fsrg3
Domain Architecture	No domain graphic available
Description	Bromodomain testis-specific protein (RING3-like protein) (Bromodomain- containing female sterile homeotic-like protein).

NSD1_HUMAN
NC score	0.070067 (rank : 257)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	155	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

PCAF_HUMAN
NC score	0.068475 (rank : 258)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	155	Target Neighborhood Hits	68	Shared Neighborhood Hits	6
SwissProt Accessions	Q92831, Q6NSK1	Gene names	PCAF
Domain Architecture
Description	Histone acetyltransferase PCAF (EC 2.3.1.48) (P300/CBP-associated factor) (P/CAF) (Histone acetylase PCAF).

DTX3L_HUMAN
NC score	0.068244 (rank : 259)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	155	Target Neighborhood Hits	187	Shared Neighborhood Hits	46
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

BAZ1B_MOUSE
NC score	0.068021 (rank : 260)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	155	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BRD3_HUMAN
NC score	0.067480 (rank : 261)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	155	Target Neighborhood Hits	369	Shared Neighborhood Hits	12
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

BRD3_MOUSE
NC score	0.067404 (rank : 262)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	155	Target Neighborhood Hits	402	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K2F0, Q8C665, Q8CAX7, Q9JI25	Gene names	Brd3, Fsrg2
Domain Architecture
Description	Bromodomain-containing protein 3 (Bromodomain-containing FSH-like protein FSRG2).

GCNL2_MOUSE
NC score	0.066338 (rank : 263)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	155	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JHD2	Gene names	Gcn5l2
Domain Architecture
Description	General control of amino acid synthesis protein 5-like 2 (EC 2.3.1.48) (Histone acetyltransferase GCN5) (mmGCN5).

TRAF2_MOUSE
NC score	0.065661 (rank : 264)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	155	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

RBBP6_HUMAN
NC score	0.065562 (rank : 265)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	155	Target Neighborhood Hits	1135	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CM007_HUMAN
NC score	0.064537 (rank : 266)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	155	Target Neighborhood Hits	422	Shared Neighborhood Hits	61
SwissProt Accessions	Q5W0B1, Q8TBY2, Q9H0T2, Q9H8M0	Gene names	C13orf7
Domain Architecture	No domain graphic available
Description	Protein C13orf7.

GOLI_HUMAN
NC score	0.064066 (rank : 267)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	155	Target Neighborhood Hits	137	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

PCGF6_MOUSE
NC score	0.062334 (rank : 268)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	155	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PHF22_HUMAN
NC score	0.062169 (rank : 269)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	8
SwissProt Accessions	Q96CB8, Q9HD71	Gene names	INTS12, PHF22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

BRD4_MOUSE
NC score	0.061956 (rank : 270)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	155	Target Neighborhood Hits	845	Shared Neighborhood Hits	16
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

BAZ1B_HUMAN
NC score	0.061723 (rank : 271)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	155	Target Neighborhood Hits	701	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BRD4_HUMAN
NC score	0.061447 (rank : 272)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	155	Target Neighborhood Hits	851	Shared Neighborhood Hits	16
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

RNF13_MOUSE
NC score	0.061396 (rank : 273)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	155	Target Neighborhood Hits	164	Shared Neighborhood Hits	26
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

PHF1_HUMAN
NC score	0.061082 (rank : 274)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	155	Target Neighborhood Hits	117	Shared Neighborhood Hits	11
SwissProt Accessions	O43189, O60929, Q96KM7	Gene names	PHF1
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1).

GOLI_MOUSE
NC score	0.061016 (rank : 275)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	155	Target Neighborhood Hits	134	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

ZSWM2_HUMAN
NC score	0.060978 (rank : 276)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	155	Target Neighborhood Hits	151	Shared Neighborhood Hits	35
SwissProt Accessions	Q8NEG5	Gene names	ZSWIM2
Domain Architecture
Description	Zinc finger SWIM domain-containing protein 2.

RN167_MOUSE
NC score	0.060483 (rank : 277)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	30
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

TAF1_HUMAN
NC score	0.060218 (rank : 278)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	P21675, Q6IUZ1	Gene names	TAF1, BA2R, CCG1, TAF2A
Domain Architecture
Description	Transcription initiation factor TFIID subunit 1 (EC 2.7.11.1) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) (TBP-associated factor 250 kDa) (p250) (Cell cycle gene 1 protein).

RSF1_HUMAN
NC score	0.059955 (rank : 279)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	155	Target Neighborhood Hits	539	Shared Neighborhood Hits	16
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

RN167_HUMAN
NC score	0.059617 (rank : 280)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	155	Target Neighborhood Hits	157	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

PCGF6_HUMAN
NC score	0.059008 (rank : 281)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	155	Target Neighborhood Hits	178	Shared Neighborhood Hits	56
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PHF1_MOUSE
NC score	0.059003 (rank : 282)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	155	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1B8, O54808	Gene names	Phf1, Tctex-3, Tctex3
Domain Architecture
Description	PHD finger protein 1 (Protein PHF1) (T-complex testis-expressed 3) (Polycomblike 1) (mPCl1).

RN122_HUMAN
NC score	0.058987 (rank : 283)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	28
SwissProt Accessions	Q9H9V4, Q52LK3	Gene names	RNF122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

PB1_HUMAN
NC score	0.058645 (rank : 284)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	155	Target Neighborhood Hits	261	Shared Neighborhood Hits	7
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

TRAF3_MOUSE
NC score	0.057800 (rank : 285)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	155	Target Neighborhood Hits	476	Shared Neighborhood Hits	77
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

RNF13_HUMAN
NC score	0.056719 (rank : 286)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	155	Target Neighborhood Hits	147	Shared Neighborhood Hits	23
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

TAF1L_HUMAN
NC score	0.056286 (rank : 287)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	155	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IZX4	Gene names	TAF1L
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID 210 kDa subunit (TBP-associated factor 210 kDa) (TAF(II)210) (TBP-associated factor 1-like).

TRAF3_HUMAN
NC score	0.055938 (rank : 288)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	155	Target Neighborhood Hits	463	Shared Neighborhood Hits	75
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

RNF19_HUMAN
NC score	0.055488 (rank : 289)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	155	Target Neighborhood Hits	105	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
NC score	0.055289 (rank : 290)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	155	Target Neighborhood Hits	96	Shared Neighborhood Hits	28
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

MGRN1_HUMAN
NC score	0.054717 (rank : 291)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	155	Target Neighborhood Hits	192	Shared Neighborhood Hits	45
SwissProt Accessions	O60291, Q86W76	Gene names	MGRN1, KIAA0544, RNF156
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1) (RING finger protein 156).

EP300_HUMAN
NC score	0.054655 (rank : 292)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	155	Target Neighborhood Hits	821	Shared Neighborhood Hits	9
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_HUMAN
NC score	0.054606 (rank : 293)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	155	Target Neighborhood Hits	941	Shared Neighborhood Hits	9
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

UB7I3_HUMAN
NC score	0.054207 (rank : 294)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	155	Target Neighborhood Hits	136	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RAPSN_MOUSE
NC score	0.054037 (rank : 295)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	155	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	P12672	Gene names	Rapsn
Domain Architecture
Description	43 kDa receptor-associated protein of the synapse (RAPsyn) (Acetylcholine receptor-associated 43 kDa protein) (43 kDa postsynaptic protein).

CHD5_HUMAN
NC score	0.053906 (rank : 296)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	155	Target Neighborhood Hits	349	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

MGRN1_MOUSE
NC score	0.053824 (rank : 297)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	155	Target Neighborhood Hits	149	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D074, Q3U5V9, Q3UDA1, Q6ZQ97, Q8BZM9	Gene names	Mgrn1, Kiaa0544
Domain Architecture	No domain graphic available
Description	Probable E3 ubiquitin-protein ligase MGRN1 (EC 6.3.2.-) (Mahogunin ring finger protein 1).

RN122_MOUSE
NC score	0.052882 (rank : 298)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	155	Target Neighborhood Hits	121	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BP31, Q80VA7, Q8BGD3	Gene names	Rnf122
Domain Architecture	No domain graphic available
Description	RING finger protein 122.

CBP_MOUSE
NC score	0.052204 (rank : 299)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	155	Target Neighborhood Hits	1051	Shared Neighborhood Hits	7
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CHD4_MOUSE
NC score	0.052153 (rank : 300)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	155	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD4_HUMAN
NC score	0.052023 (rank : 301)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	155	Target Neighborhood Hits	365	Shared Neighborhood Hits	12
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

PHF22_MOUSE
NC score	0.051373 (rank : 302)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	155	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D168, Q3U2Q5, Q921U2	Gene names	Ints12, Phf22
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 12 (PHD finger protein 22).

CHD3_HUMAN
NC score	0.050453 (rank : 303)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	155	Target Neighborhood Hits	397	Shared Neighborhood Hits	12
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

BRD8_HUMAN
NC score	0.050040 (rank : 304)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	155	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

EGLN1_HUMAN
NC score	0.029865 (rank : 305)	θ value	1.38821 (rank : 96)
Query Neighborhood Hits	155	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q9GZT9, Q8N3M8, Q9BZS8, Q9BZT0	Gene names	EGLN1, C1orf12
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20).

SYCP1_MOUSE
NC score	0.027717 (rank : 306)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	155	Target Neighborhood Hits	1456	Shared Neighborhood Hits	47
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EGLN1_MOUSE
NC score	0.025856 (rank : 307)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	155	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q91YE3, Q8VHJ2, Q922P3	Gene names	Egln1
Domain Architecture
Description	Egl nine homolog 1 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-prolyl hydroxylase 2) (HIF-PH2) (HPH-2) (SM-20).

GOGA3_MOUSE
NC score	0.024308 (rank : 308)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	155	Target Neighborhood Hits	1437	Shared Neighborhood Hits	44
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

MYCB2_MOUSE
NC score	0.021639 (rank : 309)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	155	Target Neighborhood Hits	307	Shared Neighborhood Hits	14
SwissProt Accessions	Q7TPH6, Q6PCM8	Gene names	Mycbp2, Pam, Phr1
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

MYCB2_HUMAN
NC score	0.020272 (rank : 310)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	155	Target Neighborhood Hits	390	Shared Neighborhood Hits	14
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

ITAL_HUMAN
NC score	0.017279 (rank : 311)	θ value	0.125558 (rank : 76)
Query Neighborhood Hits	155	Target Neighborhood Hits	71	Shared Neighborhood Hits	4
SwissProt Accessions	P20701, O43746, Q45H73, Q9UBC8	Gene names	ITGAL, CD11A
Domain Architecture
Description	Integrin alpha-L precursor (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD11a antigen).

REST_HUMAN
NC score	0.015412 (rank : 312)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	155	Target Neighborhood Hits	1605	Shared Neighborhood Hits	48
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ZN385_HUMAN
NC score	0.013695 (rank : 313)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	155	Target Neighborhood Hits	614	Shared Neighborhood Hits	8
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

SYCP1_HUMAN
NC score	0.013296 (rank : 314)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	155	Target Neighborhood Hits	1313	Shared Neighborhood Hits	31
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

FYCO1_HUMAN
NC score	0.011078 (rank : 315)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	155	Target Neighborhood Hits	1149	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

GOGA3_HUMAN
NC score	0.010850 (rank : 316)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	155	Target Neighborhood Hits	1317	Shared Neighborhood Hits	33
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

IMMT_MOUSE
NC score	0.009195 (rank : 317)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	155	Target Neighborhood Hits	326	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

CCD21_HUMAN
NC score	0.007702 (rank : 318)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	155	Target Neighborhood Hits	1228	Shared Neighborhood Hits	30
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

STAB1_MOUSE
NC score	0.007637 (rank : 319)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	155	Target Neighborhood Hits	566	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

MYH3_HUMAN
NC score	0.007415 (rank : 320)	θ value	1.38821 (rank : 98)
Query Neighborhood Hits	155	Target Neighborhood Hits	1660	Shared Neighborhood Hits	45
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NCKPL_HUMAN
NC score	0.006609 (rank : 321)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	155	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	P55160	Gene names	NCKAP1L, HEM1
Domain Architecture	No domain graphic available
Description	Nck-associated protein 1-like (Membrane-associated protein HEM-1) (Hematopoietic protein 1).

BICD2_MOUSE
NC score	0.006147 (rank : 322)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	155	Target Neighborhood Hits	864	Shared Neighborhood Hits	21
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

K1C19_MOUSE
NC score	0.004485 (rank : 323)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	155	Target Neighborhood Hits	358	Shared Neighborhood Hits	14
SwissProt Accessions	P19001	Gene names	Krt19, Krt1-19
Domain Architecture
Description	Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19).

K1C15_HUMAN
NC score	0.004308 (rank : 324)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	155	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P19012, Q53XV8, Q9BUG4	Gene names	KRT15, KRTB
Domain Architecture
Description	Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15).

CTRO_MOUSE
NC score	0.003943 (rank : 325)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	155	Target Neighborhood Hits	2344	Shared Neighborhood Hits	45
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

K1C13_HUMAN
NC score	0.003927 (rank : 326)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	155	Target Neighborhood Hits	386	Shared Neighborhood Hits	15
SwissProt Accessions	P13646, Q53G54, Q6AZK5, Q8N240	Gene names	KRT13
Domain Architecture
Description	Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13).

ATP4A_MOUSE
NC score	0.003368 (rank : 327)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	155	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q64436, Q9CV46	Gene names	Atp4a
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

ATP4A_HUMAN
NC score	0.003073 (rank : 328)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	155	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	P20648, O00738	Gene names	ATP4A
Domain Architecture
Description	Potassium-transporting ATPase alpha chain 1 (EC 3.6.3.10) (Proton pump) (Gastric H+/K+ ATPase subunit alpha).

CNTN6_MOUSE
NC score	-0.000267 (rank : 329)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	155	Target Neighborhood Hits	429	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

KPCT_MOUSE
NC score	-0.003173 (rank : 330)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	155	Target Neighborhood Hits	895	Shared Neighborhood Hits	7
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	-0.003227 (rank : 331)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	155	Target Neighborhood Hits	897	Shared Neighborhood Hits	7
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

ZN254_HUMAN
NC score	-0.004740 (rank : 332)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	155	Target Neighborhood Hits	702	Shared Neighborhood Hits	4
SwissProt Accessions	O75437	Gene names	ZNF254, BMZF5
Domain Architecture
Description	Zinc finger protein 254 (Bone marrow zinc finger 5) (BMZF-5) (Hematopoietic cell-derived zinc finger protein 1) (HD-ZNF1).

ZN539_HUMAN
NC score	-0.005318 (rank : 333)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	155	Target Neighborhood Hits	758	Shared Neighborhood Hits	8
SwissProt Accessions	Q86XL7	Gene names	ZNF539
Domain Architecture	No domain graphic available
Description	Zinc finger protein 539.