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Network neighborhood for query Sequence : UB7I3_HUMAN

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UB7I3_HUMAN
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UB7I3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	136	Target Neighborhood Hits	136	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
θ value	0 (rank : 2)	NC score	0.986341 (rank : 2)
Query Neighborhood Hits	136	Target Neighborhood Hits	131	Shared Neighborhood Hits	107
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RNF14_HUMAN
θ value	2.28291e-11 (rank : 3)	NC score	0.611242 (rank : 8)
Query Neighborhood Hits	136	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

IBRD2_MOUSE
θ value	2.98157e-11 (rank : 4)	NC score	0.626763 (rank : 6)
Query Neighborhood Hits	136	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD1_HUMAN
θ value	5.08577e-11 (rank : 5)	NC score	0.639545 (rank : 3)
Query Neighborhood Hits	136	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

IBRD2_HUMAN
θ value	8.67504e-11 (rank : 6)	NC score	0.619587 (rank : 7)
Query Neighborhood Hits	136	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

RNF14_MOUSE
θ value	8.67504e-11 (rank : 7)	NC score	0.607503 (rank : 9)
Query Neighborhood Hits	136	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

UB7I4_HUMAN
θ value	1.133e-10 (rank : 8)	NC score	0.629769 (rank : 4)
Query Neighborhood Hits	136	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
θ value	1.133e-10 (rank : 9)	NC score	0.629195 (rank : 5)
Query Neighborhood Hits	136	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I1_MOUSE
θ value	4.30538e-10 (rank : 10)	NC score	0.515635 (rank : 18)
Query Neighborhood Hits	136	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

PARC_MOUSE
θ value	5.62301e-10 (rank : 11)	NC score	0.445833 (rank : 22)
Query Neighborhood Hits	136	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

UB7I1_HUMAN
θ value	5.62301e-10 (rank : 12)	NC score	0.517941 (rank : 17)
Query Neighborhood Hits	136	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

RNF31_HUMAN
θ value	1.17247e-07 (rank : 13)	NC score	0.473552 (rank : 19)
Query Neighborhood Hits	136	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

PARC_HUMAN
θ value	1.53129e-07 (rank : 14)	NC score	0.439187 (rank : 24)
Query Neighborhood Hits	136	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

ARI2_HUMAN
θ value	4.45536e-07 (rank : 15)	NC score	0.558727 (rank : 10)
Query Neighborhood Hits	136	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
θ value	4.45536e-07 (rank : 16)	NC score	0.558076 (rank : 11)
Query Neighborhood Hits	136	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

IBRD3_HUMAN
θ value	5.81887e-07 (rank : 17)	NC score	0.551431 (rank : 12)
Query Neighborhood Hits	136	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

RNF19_HUMAN
θ value	5.81887e-07 (rank : 18)	NC score	0.532716 (rank : 16)
Query Neighborhood Hits	136	Target Neighborhood Hits	105	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

RNF19_MOUSE
θ value	5.81887e-07 (rank : 19)	NC score	0.534639 (rank : 15)
Query Neighborhood Hits	136	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF31_MOUSE
θ value	8.40245e-06 (rank : 20)	NC score	0.461132 (rank : 20)
Query Neighborhood Hits	136	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

ARI1_HUMAN
θ value	1.09739e-05 (rank : 21)	NC score	0.537182 (rank : 13)
Query Neighborhood Hits	136	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
θ value	1.09739e-05 (rank : 22)	NC score	0.537077 (rank : 14)
Query Neighborhood Hits	136	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

PRKN2_HUMAN
θ value	3.19293e-05 (rank : 23)	NC score	0.450344 (rank : 21)
Query Neighborhood Hits	136	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PRKN2_MOUSE
θ value	0.000158464 (rank : 24)	NC score	0.445541 (rank : 23)
Query Neighborhood Hits	136	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

TRI50_MOUSE
θ value	0.00869519 (rank : 25)	NC score	0.146552 (rank : 44)
Query Neighborhood Hits	136	Target Neighborhood Hits	326	Shared Neighborhood Hits	75
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

P2RX7_HUMAN
θ value	0.0252991 (rank : 26)	NC score	0.043189 (rank : 217)
Query Neighborhood Hits	136	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q99572, O14991, Q96EV7	Gene names	P2RX7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

RN152_HUMAN
θ value	0.0252991 (rank : 27)	NC score	0.201374 (rank : 27)
Query Neighborhood Hits	136	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RN152_MOUSE
θ value	0.0252991 (rank : 28)	NC score	0.203260 (rank : 26)
Query Neighborhood Hits	136	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

TRIM6_HUMAN
θ value	0.0252991 (rank : 29)	NC score	0.134631 (rank : 50)
Query Neighborhood Hits	136	Target Neighborhood Hits	412	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

TRI50_HUMAN
θ value	0.0330416 (rank : 30)	NC score	0.143057 (rank : 46)
Query Neighborhood Hits	136	Target Neighborhood Hits	294	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI59_MOUSE
θ value	0.0330416 (rank : 31)	NC score	0.170293 (rank : 33)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	79
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
θ value	0.0431538 (rank : 32)	NC score	0.168814 (rank : 34)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

RNF4_HUMAN
θ value	0.0563607 (rank : 33)	NC score	0.203463 (rank : 25)
Query Neighborhood Hits	136	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RNF4_MOUSE
θ value	0.0563607 (rank : 34)	NC score	0.201308 (rank : 28)
Query Neighborhood Hits	136	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

TRIM6_MOUSE
θ value	0.0736092 (rank : 35)	NC score	0.135415 (rank : 48)
Query Neighborhood Hits	136	Target Neighborhood Hits	451	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

NEIL3_HUMAN
θ value	0.0961366 (rank : 36)	NC score	0.098718 (rank : 107)
Query Neighborhood Hits	136	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

RING1_HUMAN
θ value	0.125558 (rank : 37)	NC score	0.176627 (rank : 29)
Query Neighborhood Hits	136	Target Neighborhood Hits	219	Shared Neighborhood Hits	74
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
θ value	0.125558 (rank : 38)	NC score	0.175344 (rank : 30)
Query Neighborhood Hits	136	Target Neighborhood Hits	220	Shared Neighborhood Hits	74
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

TRI68_MOUSE
θ value	0.125558 (rank : 39)	NC score	0.126484 (rank : 58)
Query Neighborhood Hits	136	Target Neighborhood Hits	356	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

RING2_HUMAN
θ value	0.163984 (rank : 40)	NC score	0.170967 (rank : 32)
Query Neighborhood Hits	136	Target Neighborhood Hits	201	Shared Neighborhood Hits	72
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

RING2_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.171001 (rank : 31)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

TRI13_HUMAN
θ value	0.163984 (rank : 42)	NC score	0.160232 (rank : 38)
Query Neighborhood Hits	136	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI32_HUMAN
θ value	0.163984 (rank : 43)	NC score	0.168512 (rank : 35)
Query Neighborhood Hits	136	Target Neighborhood Hits	264	Shared Neighborhood Hits	73
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
θ value	0.163984 (rank : 44)	NC score	0.166652 (rank : 36)
Query Neighborhood Hits	136	Target Neighborhood Hits	271	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

NEIL3_MOUSE
θ value	0.21417 (rank : 45)	NC score	0.092553 (rank : 126)
Query Neighborhood Hits	136	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

RN168_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.153045 (rank : 41)
Query Neighborhood Hits	136	Target Neighborhood Hits	370	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

SMRA3_HUMAN
θ value	0.279714 (rank : 47)	NC score	0.100229 (rank : 99)
Query Neighborhood Hits	136	Target Neighborhood Hits	265	Shared Neighborhood Hits	73
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI73_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.161508 (rank : 37)
Query Neighborhood Hits	136	Target Neighborhood Hits	258	Shared Neighborhood Hits	75
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI22_HUMAN
θ value	0.365318 (rank : 49)	NC score	0.139613 (rank : 47)
Query Neighborhood Hits	136	Target Neighborhood Hits	396	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

RN168_MOUSE
θ value	0.47712 (rank : 50)	NC score	0.145177 (rank : 45)
Query Neighborhood Hits	136	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI13_MOUSE
θ value	0.47712 (rank : 51)	NC score	0.157128 (rank : 40)
Query Neighborhood Hits	136	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

TRI74_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.158629 (rank : 39)
Query Neighborhood Hits	136	Target Neighborhood Hits	249	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRIM5_HUMAN
θ value	0.47712 (rank : 53)	NC score	0.131442 (rank : 56)
Query Neighborhood Hits	136	Target Neighborhood Hits	424	Shared Neighborhood Hits	81
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

AB1IP_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.026977 (rank : 226)
Query Neighborhood Hits	136	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

PKHA6_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.034634 (rank : 224)
Query Neighborhood Hits	136	Target Neighborhood Hits	556	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	0.62314 (rank : 56)	NC score	0.034785 (rank : 222)
Query Neighborhood Hits	136	Target Neighborhood Hits	591	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

POK7_HUMAN
θ value	0.62314 (rank : 57)	NC score	0.077877 (rank : 152)
Query Neighborhood Hits	136	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

TAB2_MOUSE
θ value	0.62314 (rank : 58)	NC score	0.094626 (rank : 123)
Query Neighborhood Hits	136	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TRAF6_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.110952 (rank : 79)
Query Neighborhood Hits	136	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

POK11_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.081028 (rank : 145)
Query Neighborhood Hits	136	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P87893	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Pol protein (HERV-K101 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

POK12_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.053552 (rank : 208)
Query Neighborhood Hits	136	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK17_HUMAN
θ value	0.813845 (rank : 62)	NC score	0.077038 (rank : 157)
Query Neighborhood Hits	136	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK20_HUMAN
θ value	0.813845 (rank : 63)	NC score	0.066242 (rank : 173)
Query Neighborhood Hits	136	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQG0, Q6KH06, Q86YP3	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_3q27.3 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK2_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.077047 (rank : 155)
Query Neighborhood Hits	136	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXR3, Q6KH04, Q9BXR4, Q9UKH5, Q9UP31, Q9WIK9, Q9WJR4	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein) (HERV-K108 Pol protein) (HERV-K(C7) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK4_HUMAN
θ value	0.813845 (rank : 65)	NC score	0.082254 (rank : 142)
Query Neighborhood Hits	136	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	P63128, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Pol protein (HERV-K109 Pol protein) (HERV-K(C6) Pol protein).

POK5_HUMAN
θ value	0.813845 (rank : 66)	NC score	0.077041 (rank : 156)
Query Neighborhood Hits	136	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	P63132	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
θ value	0.813845 (rank : 67)	NC score	0.077032 (rank : 158)
Query Neighborhood Hits	136	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

RN125_MOUSE
θ value	0.813845 (rank : 68)	NC score	0.150124 (rank : 42)
Query Neighborhood Hits	136	Target Neighborhood Hits	220	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

SMRA3_MOUSE
θ value	0.813845 (rank : 69)	NC score	0.095482 (rank : 118)
Query Neighborhood Hits	136	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TRI40_HUMAN
θ value	0.813845 (rank : 70)	NC score	0.149655 (rank : 43)
Query Neighborhood Hits	136	Target Neighborhood Hits	279	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRIM3_HUMAN
θ value	0.813845 (rank : 71)	NC score	0.135090 (rank : 49)
Query Neighborhood Hits	136	Target Neighborhood Hits	357	Shared Neighborhood Hits	81
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TULP4_HUMAN
θ value	0.813845 (rank : 72)	NC score	0.024119 (rank : 227)
Query Neighborhood Hits	136	Target Neighborhood Hits	426	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

CHFR_HUMAN
θ value	1.06291 (rank : 73)	NC score	0.134163 (rank : 51)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

CHFR_MOUSE
θ value	1.06291 (rank : 74)	NC score	0.133147 (rank : 54)
Query Neighborhood Hits	136	Target Neighborhood Hits	264	Shared Neighborhood Hits	69
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

NPL4_HUMAN
θ value	1.06291 (rank : 75)	NC score	0.085419 (rank : 136)
Query Neighborhood Hits	136	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_MOUSE
θ value	1.06291 (rank : 76)	NC score	0.085536 (rank : 134)
Query Neighborhood Hits	136	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

PCGF6_HUMAN
θ value	1.06291 (rank : 77)	NC score	0.114452 (rank : 72)
Query Neighborhood Hits	136	Target Neighborhood Hits	178	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_MOUSE
θ value	1.06291 (rank : 78)	NC score	0.115649 (rank : 71)
Query Neighborhood Hits	136	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

RFWD2_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.095551 (rank : 117)
Query Neighborhood Hits	136	Target Neighborhood Hits	518	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	1.06291 (rank : 80)	NC score	0.095612 (rank : 116)
Query Neighborhood Hits	136	Target Neighborhood Hits	535	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

TAB2_HUMAN
θ value	1.06291 (rank : 81)	NC score	0.087152 (rank : 132)
Query Neighborhood Hits	136	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TAB3_HUMAN
θ value	1.06291 (rank : 82)	NC score	0.079350 (rank : 148)
Query Neighborhood Hits	136	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TRAF6_MOUSE
θ value	1.06291 (rank : 83)	NC score	0.109142 (rank : 83)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	69
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

ZN553_HUMAN
θ value	1.06291 (rank : 84)	NC score	0.000336 (rank : 233)
Query Neighborhood Hits	136	Target Neighborhood Hits	760	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

RN166_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.133402 (rank : 53)
Query Neighborhood Hits	136	Target Neighborhood Hits	240	Shared Neighborhood Hits	75
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

RN166_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.132606 (rank : 55)
Query Neighborhood Hits	136	Target Neighborhood Hits	248	Shared Neighborhood Hits	75
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRI60_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.112870 (rank : 75)
Query Neighborhood Hits	136	Target Neighborhood Hits	357	Shared Neighborhood Hits	78
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

BRE1B_HUMAN
θ value	1.81305 (rank : 88)	NC score	0.040146 (rank : 221)
Query Neighborhood Hits	136	Target Neighborhood Hits	1040	Shared Neighborhood Hits	64
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	1.81305 (rank : 89)	NC score	0.041652 (rank : 220)
Query Neighborhood Hits	136	Target Neighborhood Hits	970	Shared Neighborhood Hits	64
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

DTX3_HUMAN
θ value	1.81305 (rank : 90)	NC score	0.108774 (rank : 84)
Query Neighborhood Hits	136	Target Neighborhood Hits	198	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

KI67_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.031686 (rank : 225)
Query Neighborhood Hits	136	Target Neighborhood Hits	581	Shared Neighborhood Hits	6
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

RN125_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.133552 (rank : 52)
Query Neighborhood Hits	136	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

TRAF3_HUMAN
θ value	1.81305 (rank : 93)	NC score	0.059638 (rank : 188)
Query Neighborhood Hits	136	Target Neighborhood Hits	463	Shared Neighborhood Hits	55
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRIM3_MOUSE
θ value	1.81305 (rank : 94)	NC score	0.127276 (rank : 57)
Query Neighborhood Hits	136	Target Neighborhood Hits	351	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

DTX3_MOUSE
θ value	2.36792 (rank : 95)	NC score	0.112102 (rank : 77)
Query Neighborhood Hits	136	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

HLF_HUMAN
θ value	2.36792 (rank : 96)	NC score	0.043090 (rank : 218)
Query Neighborhood Hits	136	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

HLF_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.043081 (rank : 219)
Query Neighborhood Hits	136	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

RO52_HUMAN
θ value	2.36792 (rank : 98)	NC score	0.112916 (rank : 74)
Query Neighborhood Hits	136	Target Neighborhood Hits	419	Shared Neighborhood Hits	78
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TAB3_MOUSE
θ value	2.36792 (rank : 99)	NC score	0.068114 (rank : 170)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TRI68_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.116583 (rank : 68)
Query Neighborhood Hits	136	Target Neighborhood Hits	267	Shared Neighborhood Hits	81
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

COMP_MOUSE
θ value	3.0926 (rank : 101)	NC score	0.009618 (rank : 228)
Query Neighborhood Hits	136	Target Neighborhood Hits	290	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TRIM2_MOUSE
θ value	3.0926 (rank : 102)	NC score	0.122753 (rank : 64)
Query Neighborhood Hits	136	Target Neighborhood Hits	331	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

BOC_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.003137 (rank : 231)
Query Neighborhood Hits	136	Target Neighborhood Hits	543	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

TRI30_MOUSE
θ value	4.03905 (rank : 104)	NC score	0.124106 (rank : 61)
Query Neighborhood Hits	136	Target Neighborhood Hits	434	Shared Neighborhood Hits	79
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRI35_MOUSE
θ value	4.03905 (rank : 105)	NC score	0.117492 (rank : 67)
Query Neighborhood Hits	136	Target Neighborhood Hits	465	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRIM2_HUMAN
θ value	4.03905 (rank : 106)	NC score	0.123798 (rank : 62)
Query Neighborhood Hits	136	Target Neighborhood Hits	330	Shared Neighborhood Hits	83
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

ZN306_HUMAN
θ value	4.03905 (rank : 107)	NC score	-0.002396 (rank : 235)
Query Neighborhood Hits	136	Target Neighborhood Hits	757	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRR0, Q5VXH3, Q92972, Q9H4T3	Gene names	ZNF306, ZFP47, ZSCAN13
Domain Architecture
Description	Zinc finger protein 306 (Zinc finger protein 47 homolog) (Zfp-47) (Zf47) (Zinc finger and SCAN domain-containing protein 13).

BFAR_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.107763 (rank : 85)
Query Neighborhood Hits	136	Target Neighborhood Hits	222	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI11_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.107508 (rank : 87)
Query Neighborhood Hits	136	Target Neighborhood Hits	316	Shared Neighborhood Hits	75
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.107267 (rank : 88)
Query Neighborhood Hits	136	Target Neighborhood Hits	329	Shared Neighborhood Hits	74
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

TRI15_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.093705 (rank : 124)
Query Neighborhood Hits	136	Target Neighborhood Hits	395	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI48_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.107713 (rank : 86)
Query Neighborhood Hits	136	Target Neighborhood Hits	192	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

ZN406_HUMAN
θ value	5.27518 (rank : 113)	NC score	-0.000929 (rank : 234)
Query Neighborhood Hits	136	Target Neighborhood Hits	794	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P243, Q3MIM5, Q6PJ01, Q75PJ7, Q75PJ9, Q86X64	Gene names	ZNF406, KIAA1485
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406 (Protein ZFAT).

NKX31_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.001189 (rank : 232)
Query Neighborhood Hits	136	Target Neighborhood Hits	379	Shared Neighborhood Hits	2
SwissProt Accessions	P97436, O09087	Gene names	Nkx3-1, Nkx-3.1, Nkx3a
Domain Architecture
Description	Homeobox protein Nkx-3.1.

RAD18_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.078164 (rank : 151)
Query Neighborhood Hits	136	Target Neighborhood Hits	230	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

RN165_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.034783 (rank : 223)
Query Neighborhood Hits	136	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

RN183_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.124896 (rank : 60)
Query Neighborhood Hits	136	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

SEM6B_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.003762 (rank : 230)
Query Neighborhood Hits	136	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

TOPRS_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.095314 (rank : 119)
Query Neighborhood Hits	136	Target Neighborhood Hits	286	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TOPRS_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.096703 (rank : 115)
Query Neighborhood Hits	136	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI10_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.120437 (rank : 65)
Query Neighborhood Hits	136	Target Neighborhood Hits	315	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

TRI10_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.123392 (rank : 63)
Query Neighborhood Hits	136	Target Neighborhood Hits	285	Shared Neighborhood Hits	85
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRI17_MOUSE
θ value	6.88961 (rank : 123)	NC score	0.098844 (rank : 105)
Query Neighborhood Hits	136	Target Neighborhood Hits	620	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRIM8_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.104132 (rank : 95)
Query Neighborhood Hits	136	Target Neighborhood Hits	650	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.104834 (rank : 94)
Query Neighborhood Hits	136	Target Neighborhood Hits	674	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

BRCA1_MOUSE
θ value	8.99809 (rank : 126)	NC score	0.099191 (rank : 104)
Query Neighborhood Hits	136	Target Neighborhood Hits	436	Shared Neighborhood Hits	72
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

MNAB_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.055106 (rank : 199)
Query Neighborhood Hits	136	Target Neighborhood Hits	196	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

MNAB_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.054002 (rank : 206)
Query Neighborhood Hits	136	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

PML_MOUSE
θ value	8.99809 (rank : 129)	NC score	0.061851 (rank : 183)
Query Neighborhood Hits	136	Target Neighborhood Hits	246	Shared Neighborhood Hits	51
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

POK9_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.073501 (rank : 161)
Query Neighborhood Hits	136	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P63134	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Pol protein (HERV-K104 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

RN183_MOUSE
θ value	8.99809 (rank : 131)	NC score	0.118929 (rank : 66)
Query Neighborhood Hits	136	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

RNF32_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.053864 (rank : 207)
Query Neighborhood Hits	136	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

RO52_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.110734 (rank : 81)
Query Neighborhood Hits	136	Target Neighborhood Hits	360	Shared Neighborhood Hits	77
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TAF4_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.006993 (rank : 229)
Query Neighborhood Hits	136	Target Neighborhood Hits	687	Shared Neighborhood Hits	7
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

TRI12_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.124970 (rank : 59)
Query Neighborhood Hits	136	Target Neighborhood Hits	387	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

TRI62_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.104891 (rank : 93)
Query Neighborhood Hits	136	Target Neighborhood Hits	478	Shared Neighborhood Hits	74
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

BFAR_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.089772 (rank : 130)
Query Neighborhood Hits	136	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

BRCA1_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.095048 (rank : 122)
Query Neighborhood Hits	136	Target Neighborhood Hits	381	Shared Neighborhood Hits	73
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

BSPRY_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.050676 (rank : 215)
Query Neighborhood Hits	136	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

BSPRY_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.051775 (rank : 211)
Query Neighborhood Hits	136	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

CUL7_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.115896 (rank : 69)
Query Neighborhood Hits	136	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

DTX3L_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.060104 (rank : 187)
Query Neighborhood Hits	136	Target Neighborhood Hits	187	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

ERMAP_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.052770 (rank : 209)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

MEFV_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.068252 (rank : 169)
Query Neighborhood Hits	136	Target Neighborhood Hits	431	Shared Neighborhood Hits	39
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

MEFV_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.064285 (rank : 174)
Query Neighborhood Hits	136	Target Neighborhood Hits	236	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

NHLC1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.057813 (rank : 192)
Query Neighborhood Hits	136	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

NHLC1_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.055006 (rank : 201)
Query Neighborhood Hits	136	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

PCGF2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.060649 (rank : 185)
Query Neighborhood Hits	136	Target Neighborhood Hits	222	Shared Neighborhood Hits	52
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.060585 (rank : 186)
Query Neighborhood Hits	136	Target Neighborhood Hits	213	Shared Neighborhood Hits	52
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PCGF4_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.063088 (rank : 180)
Query Neighborhood Hits	136	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.063032 (rank : 181)
Query Neighborhood Hits	136	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

PEX10_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.107228 (rank : 89)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	74
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

PML_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.057008 (rank : 195)
Query Neighborhood Hits	136	Target Neighborhood Hits	248	Shared Neighborhood Hits	50
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

POK10_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.057055 (rank : 194)
Query Neighborhood Hits	136	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	P10266, P87890, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pol protein (HERV-K10 Pol protein) (HERV-K107 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK3_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.070086 (rank : 166)
Query Neighborhood Hits	136	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

RAD18_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.072922 (rank : 163)
Query Neighborhood Hits	136	Target Neighborhood Hits	284	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RAG1_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.069846 (rank : 167)
Query Neighborhood Hits	136	Target Neighborhood Hits	203	Shared Neighborhood Hits	58
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RAG1_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.064029 (rank : 176)
Query Neighborhood Hits	136	Target Neighborhood Hits	189	Shared Neighborhood Hits	56
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

RFPL1_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.056790 (rank : 196)
Query Neighborhood Hits	136	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

RFPL2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.057172 (rank : 193)
Query Neighborhood Hits	136	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

RFPL3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.062759 (rank : 182)
Query Neighborhood Hits	136	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

RN141_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.063580 (rank : 178)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.063305 (rank : 179)
Query Neighborhood Hits	136	Target Neighborhood Hits	200	Shared Neighborhood Hits	62
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN146_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.070933 (rank : 164)
Query Neighborhood Hits	136	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

RN146_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.069007 (rank : 168)
Query Neighborhood Hits	136	Target Neighborhood Hits	161	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

RN169_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.054771 (rank : 203)
Query Neighborhood Hits	136	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

RN185_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.083805 (rank : 140)
Query Neighborhood Hits	136	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.082880 (rank : 141)
Query Neighborhood Hits	136	Target Neighborhood Hits	211	Shared Neighborhood Hits	71
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RNF32_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.050343 (rank : 216)
Query Neighborhood Hits	136	Target Neighborhood Hits	133	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

RNF39_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.082221 (rank : 143)
Query Neighborhood Hits	136	Target Neighborhood Hits	200	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF41_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.079537 (rank : 147)
Query Neighborhood Hits	136	Target Neighborhood Hits	226	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.079763 (rank : 146)
Query Neighborhood Hits	136	Target Neighborhood Hits	224	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF5_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.077788 (rank : 153)
Query Neighborhood Hits	136	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

RNF5_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.078521 (rank : 150)
Query Neighborhood Hits	136	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RNF8_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.082200 (rank : 144)
Query Neighborhood Hits	136	Target Neighborhood Hits	622	Shared Neighborhood Hits	77
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

RNF8_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.091923 (rank : 128)
Query Neighborhood Hits	136	Target Neighborhood Hits	618	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

TRAF4_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.051388 (rank : 212)
Query Neighborhood Hits	136	Target Neighborhood Hits	373	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRI14_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.061297 (rank : 184)
Query Neighborhood Hits	136	Target Neighborhood Hits	143	Shared Neighborhood Hits	34
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

TRI14_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.059474 (rank : 189)
Query Neighborhood Hits	136	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI17_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.100775 (rank : 98)
Query Neighborhood Hits	136	Target Neighborhood Hits	318	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

TRI18_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.067276 (rank : 171)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.066861 (rank : 172)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	70
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

TRI25_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.086647 (rank : 133)
Query Neighborhood Hits	136	Target Neighborhood Hits	472	Shared Neighborhood Hits	79
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

TRI25_MOUSE
θ value	θ > 10 (rank : 184)	NC score	0.084346 (rank : 139)
Query Neighborhood Hits	136	Target Neighborhood Hits	446	Shared Neighborhood Hits	74
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

TRI26_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.110769 (rank : 80)
Query Neighborhood Hits	136	Target Neighborhood Hits	335	Shared Neighborhood Hits	77
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

TRI26_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.111089 (rank : 78)
Query Neighborhood Hits	136	Target Neighborhood Hits	339	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRI27_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.098435 (rank : 108)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	73
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI27_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.095293 (rank : 121)
Query Neighborhood Hits	136	Target Neighborhood Hits	261	Shared Neighborhood Hits	68
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

TRI29_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.051177 (rank : 213)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	33
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

TRI29_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.056009 (rank : 198)
Query Neighborhood Hits	136	Target Neighborhood Hits	306	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

TRI31_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.115685 (rank : 70)
Query Neighborhood Hits	136	Target Neighborhood Hits	299	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

TRI34_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.106967 (rank : 90)
Query Neighborhood Hits	136	Target Neighborhood Hits	416	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

TRI34_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.099546 (rank : 103)
Query Neighborhood Hits	136	Target Neighborhood Hits	332	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

TRI35_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.113396 (rank : 73)
Query Neighborhood Hits	136	Target Neighborhood Hits	382	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

TRI36_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.054759 (rank : 204)
Query Neighborhood Hits	136	Target Neighborhood Hits	282	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI36_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.052170 (rank : 210)
Query Neighborhood Hits	136	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRI37_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.077347 (rank : 154)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

TRI37_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.079126 (rank : 149)
Query Neighborhood Hits	136	Target Neighborhood Hits	316	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

TRI38_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.098733 (rank : 106)
Query Neighborhood Hits	136	Target Neighborhood Hits	373	Shared Neighborhood Hits	75
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

TRI39_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.096802 (rank : 114)
Query Neighborhood Hits	136	Target Neighborhood Hits	693	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI39_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.097263 (rank : 111)
Query Neighborhood Hits	136	Target Neighborhood Hits	691	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI41_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.084449 (rank : 138)
Query Neighborhood Hits	136	Target Neighborhood Hits	349	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI42_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.054836 (rank : 202)
Query Neighborhood Hits	136	Target Neighborhood Hits	316	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TRI43_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.099818 (rank : 101)
Query Neighborhood Hits	136	Target Neighborhood Hits	341	Shared Neighborhood Hits	72
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI44_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.058469 (rank : 191)
Query Neighborhood Hits	136	Target Neighborhood Hits	393	Shared Neighborhood Hits	31
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

TRI44_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.058821 (rank : 190)
Query Neighborhood Hits	136	Target Neighborhood Hits	327	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI45_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.054207 (rank : 205)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

TRI46_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.055072 (rank : 200)
Query Neighborhood Hits	136	Target Neighborhood Hits	291	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.056485 (rank : 197)
Query Neighborhood Hits	136	Target Neighborhood Hits	287	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI47_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.073120 (rank : 162)
Query Neighborhood Hits	136	Target Neighborhood Hits	286	Shared Neighborhood Hits	69
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

TRI47_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.073602 (rank : 159)
Query Neighborhood Hits	136	Target Neighborhood Hits	295	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRI49_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.095309 (rank : 120)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI52_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.096992 (rank : 112)
Query Neighborhood Hits	136	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI54_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.092142 (rank : 127)
Query Neighborhood Hits	136	Target Neighborhood Hits	209	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI54_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.098102 (rank : 109)
Query Neighborhood Hits	136	Target Neighborhood Hits	197	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRI55_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.089396 (rank : 131)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TRI56_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.096919 (rank : 113)
Query Neighborhood Hits	136	Target Neighborhood Hits	339	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI56_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.099567 (rank : 102)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	76
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI60_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.092606 (rank : 125)
Query Neighborhood Hits	136	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

TRI62_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.100092 (rank : 100)
Query Neighborhood Hits	136	Target Neighborhood Hits	584	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI63_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.085094 (rank : 137)
Query Neighborhood Hits	136	Target Neighborhood Hits	298	Shared Neighborhood Hits	59
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI63_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.085500 (rank : 135)
Query Neighborhood Hits	136	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

TRI65_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.102104 (rank : 97)
Query Neighborhood Hits	136	Target Neighborhood Hits	330	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI65_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.110174 (rank : 82)
Query Neighborhood Hits	136	Target Neighborhood Hits	340	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRIM1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.073512 (rank : 160)
Query Neighborhood Hits	136	Target Neighborhood Hits	345	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.070907 (rank : 165)
Query Neighborhood Hits	136	Target Neighborhood Hits	361	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

TRIM4_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.103656 (rank : 96)
Query Neighborhood Hits	136	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRIM7_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.097502 (rank : 110)
Query Neighborhood Hits	136	Target Neighborhood Hits	336	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRIM7_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.106017 (rank : 92)
Query Neighborhood Hits	136	Target Neighborhood Hits	358	Shared Neighborhood Hits	76
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRIM9_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.063654 (rank : 177)
Query Neighborhood Hits	136	Target Neighborhood Hits	294	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

TRIM9_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.064183 (rank : 175)
Query Neighborhood Hits	136	Target Neighborhood Hits	274	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

UHRF2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.050891 (rank : 214)
Query Neighborhood Hits	136	Target Neighborhood Hits	269	Shared Neighborhood Hits	67
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

ZN179_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.090549 (rank : 129)
Query Neighborhood Hits	136	Target Neighborhood Hits	178	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

ZN313_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.106136 (rank : 91)
Query Neighborhood Hits	136	Target Neighborhood Hits	264	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

ZN313_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.112628 (rank : 76)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

Hits sorted by NC score

UB7I3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	136	Target Neighborhood Hits	136	Shared Neighborhood Hits	136
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

UB7I3_MOUSE
NC score	0.986341 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	136	Target Neighborhood Hits	131	Shared Neighborhood Hits	107
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

IBRD1_HUMAN
NC score	0.639545 (rank : 3)	θ value	5.08577e-11 (rank : 5)
Query Neighborhood Hits	136	Target Neighborhood Hits	62	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC41, Q9BX48	Gene names	IBRDC1
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 1.

UB7I4_HUMAN
NC score	0.629769 (rank : 4)	θ value	1.133e-10 (rank : 8)
Query Neighborhood Hits	136	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	P50876	Gene names	RNF144, KIAA0161, UBCE7IP4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

UB7I4_MOUSE
NC score	0.629195 (rank : 5)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	136	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

IBRD2_MOUSE
NC score	0.626763 (rank : 6)	θ value	2.98157e-11 (rank : 4)
Query Neighborhood Hits	136	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BKD6, Q8BG97	Gene names	Ibrdc2
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2).

IBRD2_HUMAN
NC score	0.619587 (rank : 7)	θ value	8.67504e-11 (rank : 6)
Query Neighborhood Hits	136	Target Neighborhood Hits	55	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z419, Q6P4Q0, Q8N3R7, Q9BX38	Gene names	IBRDC2, P53RFP
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase IBRDC2 (EC 6.3.2.-) (IBR domain-containing protein 2) (p53-inducible RING finger protein).

RNF14_HUMAN
NC score	0.611242 (rank : 8)	θ value	2.28291e-11 (rank : 3)
Query Neighborhood Hits	136	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UBS8, O94793, Q6IBV0	Gene names	RNF14, ARA54
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein) (HFB30).

RNF14_MOUSE
NC score	0.607503 (rank : 9)	θ value	8.67504e-11 (rank : 7)
Query Neighborhood Hits	136	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9JI90, Q9D0L2, Q9D6N2, Q9D6Z8, Q9JI89	Gene names	Rnf14, Ara54, Triad2
Domain Architecture
Description	RING finger protein 14 (Androgen receptor-associated protein 54) (Triad2 protein).

ARI2_HUMAN
NC score	0.558727 (rank : 10)	θ value	4.45536e-07 (rank : 15)
Query Neighborhood Hits	136	Target Neighborhood Hits	113	Shared Neighborhood Hits	40
SwissProt Accessions	O95376, Q9HBZ6, Q9UEM9	Gene names	ARIH2, ARI2, TRIAD1
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein).

ARI2_MOUSE
NC score	0.558076 (rank : 11)	θ value	4.45536e-07 (rank : 16)
Query Neighborhood Hits	136	Target Neighborhood Hits	106	Shared Neighborhood Hits	40
SwissProt Accessions	Q9Z1K6	Gene names	Arih2, Ari2, Triad1, Uip48
Domain Architecture
Description	Protein ariadne-2 homolog (ARI-2) (Triad1 protein) (UbcM4-interacting protein 48).

IBRD3_HUMAN
NC score	0.551431 (rank : 12)	θ value	5.81887e-07 (rank : 17)
Query Neighborhood Hits	136	Target Neighborhood Hits	70	Shared Neighborhood Hits	38
SwissProt Accessions	Q6ZMZ0, Q6P6A4	Gene names	IBRDC3
Domain Architecture	No domain graphic available
Description	IBR domain-containing protein 3.

ARI1_HUMAN
NC score	0.537182 (rank : 13)	θ value	1.09739e-05 (rank : 21)
Query Neighborhood Hits	136	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y4X5, O76026, Q9H3T6, Q9UEN0, Q9UP39	Gene names	ARIH1, ARI, UBCH7BP
Domain Architecture
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6).

ARI1_MOUSE
NC score	0.537077 (rank : 14)	θ value	1.09739e-05 (rank : 22)
Query Neighborhood Hits	136	Target Neighborhood Hits	71	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z1K5, Q6PF92	Gene names	Arih1, Ari, Ubch7bp, Uip77
Domain Architecture	No domain graphic available
Description	Protein ariadne-1 homolog (ARI-1) (Ubiquitin-conjugating enzyme E2- binding protein 1) (UbcH7-binding protein) (UbcM4-interacting protein 77).

RNF19_MOUSE
NC score	0.534639 (rank : 15)	θ value	5.81887e-07 (rank : 19)
Query Neighborhood Hits	136	Target Neighborhood Hits	96	Shared Neighborhood Hits	50
SwissProt Accessions	P50636, Q9QUJ5	Gene names	Rnf19, Geg-154, Xybp
Domain Architecture
Description	RING finger protein 19 (XY body protein) (XYbp) (Gametogenesis expressed protein GEG-154) (UBCM4-interacting protein 117) (UIP117).

RNF19_HUMAN
NC score	0.532716 (rank : 16)	θ value	5.81887e-07 (rank : 18)
Query Neighborhood Hits	136	Target Neighborhood Hits	105	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NV58, Q9H5H9, Q9H8M8, Q9UFG0, Q9UFX6, Q9Y4Y1	Gene names	RNF19
Domain Architecture
Description	RING finger protein 19 (Dorfin) (Double ring-finger protein) (p38 protein).

UB7I1_HUMAN
NC score	0.517941 (rank : 17)	θ value	5.62301e-10 (rank : 12)
Query Neighborhood Hits	136	Target Neighborhood Hits	177	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NWF9, Q6Y691, Q75ML7, Q7Z2H7, Q7Z7C1, Q8NHW7, Q9NYT1	Gene names	UBCE7IP1, ZIN
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (Zinc finger protein inhibiting NF-kappa-B) (Triad domain-containing protein 3).

UB7I1_MOUSE
NC score	0.515635 (rank : 18)	θ value	4.30538e-10 (rank : 10)
Query Neighborhood Hits	136	Target Neighborhood Hits	206	Shared Neighborhood Hits	27
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

RNF31_HUMAN
NC score	0.473552 (rank : 19)	θ value	1.17247e-07 (rank : 13)
Query Neighborhood Hits	136	Target Neighborhood Hits	110	Shared Neighborhood Hits	39
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.461132 (rank : 20)	θ value	8.40245e-06 (rank : 20)
Query Neighborhood Hits	136	Target Neighborhood Hits	113	Shared Neighborhood Hits	38
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

PRKN2_HUMAN
NC score	0.450344 (rank : 21)	θ value	3.19293e-05 (rank : 23)
Query Neighborhood Hits	136	Target Neighborhood Hits	65	Shared Neighborhood Hits	24
SwissProt Accessions	O60260, Q5TFV8, Q6Q2I6, Q8NI41, Q8NI43, Q8NI44, Q8WW07	Gene names	PARK2, PRKN
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2).

PARC_MOUSE
NC score	0.445833 (rank : 22)	θ value	5.62301e-10 (rank : 11)
Query Neighborhood Hits	136	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q80TT8, Q8BKL9, Q8CGC0, Q8R363	Gene names	Parc, Kiaa0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein.

PRKN2_MOUSE
NC score	0.445541 (rank : 23)	θ value	0.000158464 (rank : 24)
Query Neighborhood Hits	136	Target Neighborhood Hits	69	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVS6, Q9ES22, Q9ES23	Gene names	Park2, Prkn
Domain Architecture	No domain graphic available
Description	Parkin (EC 6.3.2.-) (Ubiquitin E3 ligase PRKN).

PARC_HUMAN
NC score	0.439187 (rank : 24)	θ value	1.53129e-07 (rank : 14)
Query Neighborhood Hits	136	Target Neighborhood Hits	148	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IWT3, O75188, Q68CP2, Q68D92, Q8N3W9, Q9BU56	Gene names	PARC, H7AP1, KIAA0708
Domain Architecture
Description	p53-associated parkin-like cytoplasmic protein (UbcH7-associated protein 1).

RNF4_HUMAN
NC score	0.203463 (rank : 25)	θ value	0.0563607 (rank : 33)
Query Neighborhood Hits	136	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	P78317	Gene names	RNF4
Domain Architecture
Description	RING finger protein 4.

RN152_MOUSE
NC score	0.203260 (rank : 26)	θ value	0.0252991 (rank : 28)
Query Neighborhood Hits	136	Target Neighborhood Hits	109	Shared Neighborhood Hits	45
SwissProt Accessions	Q8BG47	Gene names	Rnf152
Domain Architecture	No domain graphic available
Description	RING finger protein 152.

RN152_HUMAN
NC score	0.201374 (rank : 27)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	136	Target Neighborhood Hits	107	Shared Neighborhood Hits	43
SwissProt Accessions	Q8N8N0	Gene names	RNF152
Domain Architecture
Description	RING finger protein 152.

RNF4_MOUSE
NC score	0.201308 (rank : 28)	θ value	0.0563607 (rank : 34)
Query Neighborhood Hits	136	Target Neighborhood Hits	212	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QZS2, O35941, Q541Z6	Gene names	Rnf4
Domain Architecture
Description	RING finger protein 4.

RING1_HUMAN
NC score	0.176627 (rank : 29)	θ value	0.125558 (rank : 37)
Query Neighborhood Hits	136	Target Neighborhood Hits	219	Shared Neighborhood Hits	74
SwissProt Accessions	Q06587, Q5JP96, Q5SQW2, Q86V19	Gene names	RING1, RNF1
Domain Architecture
Description	Polycomb complex protein RING1 (RING finger protein 1).

RING1_MOUSE
NC score	0.175344 (rank : 30)	θ value	0.125558 (rank : 38)
Query Neighborhood Hits	136	Target Neighborhood Hits	220	Shared Neighborhood Hits	74
SwissProt Accessions	O35730, Q3U242, Q3U333, Q4FK33, Q63ZX8, Q921Z8	Gene names	Ring1, Ring1A, Rnf1
Domain Architecture	No domain graphic available
Description	Polycomb complex protein RING1 (RING finger protein 1) (Transcription repressor Ring1A).

RING2_MOUSE
NC score	0.171001 (rank : 31)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CQJ4, O35699, O35729, Q4FJV5, Q8C1X8	Gene names	Rnf2, DinG, Ring1b
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b).

RING2_HUMAN
NC score	0.170967 (rank : 32)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	136	Target Neighborhood Hits	201	Shared Neighborhood Hits	72
SwissProt Accessions	Q99496, Q5TEN1, Q5TEN2	Gene names	RNF2, BAP1, DING, HIPI3, RING1B
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein RING2 (EC 6.3.2.-) (RING finger protein 2) (RING finger protein 1B) (RING1b) (RING finger protein BAP-1) (DinG protein) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3).

TRI59_MOUSE
NC score	0.170293 (rank : 33)	θ value	0.0330416 (rank : 31)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	79
SwissProt Accessions	Q922Y2, Q9CSP2, Q9CUD5, Q9D740	Gene names	Trim59, Mrf1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (RING finger protein 1).

TRI59_HUMAN
NC score	0.168814 (rank : 34)	θ value	0.0431538 (rank : 32)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	79
SwissProt Accessions	Q8IWR1	Gene names	TRIM59, RNF104, TRIM57, TSBF1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 59 (Tumor suppressor TSBF-1) (RING finger protein 104).

TRI32_HUMAN
NC score	0.168512 (rank : 35)	θ value	0.163984 (rank : 43)
Query Neighborhood Hits	136	Target Neighborhood Hits	264	Shared Neighborhood Hits	73
SwissProt Accessions	Q13049, Q9NQP8	Gene names	TRIM32, HT2A
Domain Architecture
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-) (Zinc finger protein HT2A) (72 kDa Tat-interacting protein).

TRI32_MOUSE
NC score	0.166652 (rank : 36)	θ value	0.163984 (rank : 44)
Query Neighborhood Hits	136	Target Neighborhood Hits	271	Shared Neighborhood Hits	71
SwissProt Accessions	Q8CH72, Q8K055	Gene names	Trim32
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 32 (EC 6.3.2.-).

TRI73_HUMAN
NC score	0.161508 (rank : 37)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	136	Target Neighborhood Hits	258	Shared Neighborhood Hits	75
SwissProt Accessions	Q86UV7, Q8N0S3	Gene names	TRIM73, TRIM50B
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B).

TRI13_HUMAN
NC score	0.160232 (rank : 38)	θ value	0.163984 (rank : 42)
Query Neighborhood Hits	136	Target Neighborhood Hits	274	Shared Neighborhood Hits	79
SwissProt Accessions	O60858, Q9BQ47, Q9C021	Gene names	TRIM13, LEU5, RFP2, RNF77
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2) (Leukemia-associated protein 5) (B- cell chronic lymphocytic leukemia tumor suppressor Leu5) (RING finger protein 77).

TRI74_HUMAN
NC score	0.158629 (rank : 39)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	136	Target Neighborhood Hits	249	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UV6	Gene names	TRIM74, TRIM50C
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C).

TRI13_MOUSE
NC score	0.157128 (rank : 40)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	136	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q9CYB0, Q8CEV0, Q923J0, Q925P1, Q99PQ0	Gene names	Trim13, Rfp2
Domain Architecture
Description	Tripartite motif-containing protein 13 (Ret finger protein 2) (Putative tumor suppressor RFP2).

RN168_HUMAN
NC score	0.153045 (rank : 41)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	136	Target Neighborhood Hits	370	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IYW5, Q8NA67, Q96NS4	Gene names	RNF168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

RN125_MOUSE
NC score	0.150124 (rank : 42)	θ value	0.813845 (rank : 68)
Query Neighborhood Hits	136	Target Neighborhood Hits	220	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D9R0, Q52KL4, Q8C7F2	Gene names	Rnf125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-).

TRI40_HUMAN
NC score	0.149655 (rank : 43)	θ value	0.813845 (rank : 70)
Query Neighborhood Hits	136	Target Neighborhood Hits	279	Shared Neighborhood Hits	76
SwissProt Accessions	Q6P9F5, Q8TD96	Gene names	TRIM40, RNF35
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 40 (RING finger protein 35).

TRI50_MOUSE
NC score	0.146552 (rank : 44)	θ value	0.00869519 (rank : 25)
Query Neighborhood Hits	136	Target Neighborhood Hits	326	Shared Neighborhood Hits	75
SwissProt Accessions	Q810I2	Gene names	Trim50
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

RN168_MOUSE
NC score	0.145177 (rank : 45)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	136	Target Neighborhood Hits	440	Shared Neighborhood Hits	67
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

TRI50_HUMAN
NC score	0.143057 (rank : 46)	θ value	0.0330416 (rank : 30)
Query Neighborhood Hits	136	Target Neighborhood Hits	294	Shared Neighborhood Hits	73
SwissProt Accessions	Q86XT4, Q86XT3	Gene names	TRIM50, TRIM50A
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 50.

TRI22_HUMAN
NC score	0.139613 (rank : 47)	θ value	0.365318 (rank : 49)
Query Neighborhood Hits	136	Target Neighborhood Hits	396	Shared Neighborhood Hits	84
SwissProt Accessions	Q8IYM9, Q15521	Gene names	TRIM22, RNF94, STAF50
Domain Architecture
Description	Tripartite motif-containing protein 22 (RING finger protein 94) (50 kDa-stimulated trans-acting factor) (Staf-50).

TRIM6_MOUSE
NC score	0.135415 (rank : 48)	θ value	0.0736092 (rank : 35)
Query Neighborhood Hits	136	Target Neighborhood Hits	451	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BGE7, Q99PQ6	Gene names	Trim6
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 6.

TRIM3_HUMAN
NC score	0.135090 (rank : 49)	θ value	0.813845 (rank : 71)
Query Neighborhood Hits	136	Target Neighborhood Hits	357	Shared Neighborhood Hits	81
SwissProt Accessions	O75382, Q9C038, Q9C039	Gene names	TRIM3, BERP, RNF22, RNF97
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (Brain- expressed RING finger protein) (RING finger protein 97).

TRIM6_HUMAN
NC score	0.134631 (rank : 50)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	136	Target Neighborhood Hits	412	Shared Neighborhood Hits	78
SwissProt Accessions	Q9C030, Q86WZ8, Q9HCR1	Gene names	TRIM6, RNF89
Domain Architecture
Description	Tripartite motif-containing protein 6 (RING finger protein 89).

CHFR_HUMAN
NC score	0.134163 (rank : 51)	θ value	1.06291 (rank : 73)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	68
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN125_HUMAN
NC score	0.133552 (rank : 52)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	136	Target Neighborhood Hits	230	Shared Neighborhood Hits	69
SwissProt Accessions	Q96EQ8, Q9NX39	Gene names	RNF125
Domain Architecture	No domain graphic available
Description	RING finger protein 125 (EC 6.3.2.-) (T-cell RING activation protein 1) (TRAC-1).

RN166_HUMAN
NC score	0.133402 (rank : 53)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	136	Target Neighborhood Hits	240	Shared Neighborhood Hits	75
SwissProt Accessions	Q96A37, Q96DM0	Gene names	RNF166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

CHFR_MOUSE
NC score	0.133147 (rank : 54)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	136	Target Neighborhood Hits	264	Shared Neighborhood Hits	69
SwissProt Accessions	Q810L3, Q8BJZ9, Q8BWH4	Gene names	Chfr
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

RN166_MOUSE
NC score	0.132606 (rank : 55)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	136	Target Neighborhood Hits	248	Shared Neighborhood Hits	75
SwissProt Accessions	Q3U9F6	Gene names	Rnf166
Domain Architecture	No domain graphic available
Description	RING finger protein 166.

TRIM5_HUMAN
NC score	0.131442 (rank : 56)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	136	Target Neighborhood Hits	424	Shared Neighborhood Hits	81
SwissProt Accessions	Q9C035, Q8WU46, Q96SR5, Q9C031, Q9C032, Q9C033, Q9C034	Gene names	TRIM5, RNF88
Domain Architecture
Description	Tripartite motif-containing protein 5 (EC 6.3.2.-) (RING finger protein 88).

TRIM3_MOUSE
NC score	0.127276 (rank : 57)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	136	Target Neighborhood Hits	351	Shared Neighborhood Hits	80
SwissProt Accessions	Q9R1R2, Q3UMU5	Gene names	Trim3, Hac1, Rnf22
Domain Architecture
Description	Tripartite motif-containing protein 3 (RING finger protein 22) (RING finger protein HAC1).

TRI68_MOUSE
NC score	0.126484 (rank : 58)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	136	Target Neighborhood Hits	356	Shared Neighborhood Hits	81
SwissProt Accessions	Q8K243	Gene names	Trim68, Rnf137
Domain Architecture	No domain graphic available
Description	Tripartite motif containing protein 68 (Ring finger protein 137).

TRI12_MOUSE
NC score	0.124970 (rank : 59)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	136	Target Neighborhood Hits	387	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PQ1, Q9D704	Gene names	Trim12
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 12.

RN183_HUMAN
NC score	0.124896 (rank : 60)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	136	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q96D59	Gene names	RNF183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI30_MOUSE
NC score	0.124106 (rank : 61)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	136	Target Neighborhood Hits	434	Shared Neighborhood Hits	79
SwissProt Accessions	P15533, Q99K55, Q99PQ7, Q99PQ8, Q99PQ9	Gene names	Trim30, Rpt-1, Rpt1
Domain Architecture
Description	Tripartite motif-containing protein 30 (Down regulatory protein of interleukin 2 receptor).

TRIM2_HUMAN
NC score	0.123798 (rank : 62)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	136	Target Neighborhood Hits	330	Shared Neighborhood Hits	83
SwissProt Accessions	Q9C040, O60272, Q9BSI9, Q9UFZ1	Gene names	TRIM2, KIAA0517, RNF86
Domain Architecture
Description	Tripartite motif-containing protein 2 (RING finger protein 86).

TRI10_MOUSE
NC score	0.123392 (rank : 63)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	136	Target Neighborhood Hits	285	Shared Neighborhood Hits	85
SwissProt Accessions	Q9WUH5, Q80WA9, Q9CY03	Gene names	Trim10, Herf1, Rnf9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (Hematopoietic RING finger 1).

TRIM2_MOUSE
NC score	0.122753 (rank : 64)	θ value	3.0926 (rank : 102)
Query Neighborhood Hits	136	Target Neighborhood Hits	331	Shared Neighborhood Hits	81
SwissProt Accessions	Q9ESN6, Q3UHP5, Q8C981	Gene names	Trim2, Narf
Domain Architecture
Description	Tripartite motif-containing protein 2 (Neural activity-related RING finger protein).

TRI10_HUMAN
NC score	0.120437 (rank : 65)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	136	Target Neighborhood Hits	315	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UDY6, Q86Z08, Q96QB6, Q9C023, Q9C024	Gene names	TRIM10, RFB30, RNF9
Domain Architecture
Description	Tripartite motif-containing protein 10 (RING finger protein 9) (B30- RING finger protein).

RN183_MOUSE
NC score	0.118929 (rank : 66)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	136	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	Q8QZS5, Q5NBV8	Gene names	Rnf183
Domain Architecture	No domain graphic available
Description	RING finger protein 183.

TRI35_MOUSE
NC score	0.117492 (rank : 67)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	136	Target Neighborhood Hits	465	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRI68_HUMAN
NC score	0.116583 (rank : 68)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	136	Target Neighborhood Hits	267	Shared Neighborhood Hits	81
SwissProt Accessions	Q6AZZ1, Q8WZ70, Q96PF7, Q9H9C2, Q9NW18	Gene names	TRIM68, RNF137, SS56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 68 (RING finger protein 137) (SSA protein SS-56) (SS-56).

CUL7_HUMAN
NC score	0.115896 (rank : 69)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	136	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q14999, Q5T654	Gene names	CUL7, KIAA0076
Domain Architecture
Description	Cullin-7 (CUL-7).

TRI31_HUMAN
NC score	0.115685 (rank : 70)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	136	Target Neighborhood Hits	299	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BZY9, Q53H52, Q5RI37, Q5SRJ7, Q5SRJ8, Q5SS28, Q96AK4, Q96AP8, Q99579, Q9BZY8	Gene names	TRIM31, C6orf13, RNF
Domain Architecture
Description	Tripartite motif-containing protein 31.

PCGF6_MOUSE
NC score	0.115649 (rank : 71)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	136	Target Neighborhood Hits	163	Shared Neighborhood Hits	62
SwissProt Accessions	Q99NA9	Gene names	Pcgf6, Mblr, Rnf134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

PCGF6_HUMAN
NC score	0.114452 (rank : 72)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	136	Target Neighborhood Hits	178	Shared Neighborhood Hits	63
SwissProt Accessions	Q9BYE7, Q5SYD1, Q5SYD6, Q96ID9, Q96SJ1	Gene names	PCGF6, MBLR, RNF134
Domain Architecture	No domain graphic available
Description	Polycomb group RING finger protein 6 (RING finger protein 134) (Mel18 and Bmi1-like RING finger).

TRI35_HUMAN
NC score	0.113396 (rank : 73)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	136	Target Neighborhood Hits	382	Shared Neighborhood Hits	82
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

RO52_HUMAN
NC score	0.112916 (rank : 74)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	136	Target Neighborhood Hits	419	Shared Neighborhood Hits	78
SwissProt Accessions	P19474, Q96RF8	Gene names	TRIM21, RNF81, RO52, SSA1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21) (RING finger protein 81).

TRI60_HUMAN
NC score	0.112870 (rank : 75)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	136	Target Neighborhood Hits	357	Shared Neighborhood Hits	78
SwissProt Accessions	Q495X7, Q8NA35	Gene names	TRIM60, RNF129
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (RING finger protein 129).

ZN313_MOUSE
NC score	0.112628 (rank : 76)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	78
SwissProt Accessions	Q9ET26, Q3UFU8, Q8K5A2	Gene names	Znf313, Zfp228, Zfp313, Znf228
Domain Architecture
Description	Zinc finger protein 313.

DTX3_MOUSE
NC score	0.112102 (rank : 77)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	136	Target Neighborhood Hits	202	Shared Neighborhood Hits	70
SwissProt Accessions	Q80V91, Q9ER06	Gene names	Dtx3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3) (mDTX3).

TRI26_MOUSE
NC score	0.111089 (rank : 78)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	136	Target Neighborhood Hits	339	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PN3, Q8C9E9, Q8JZT7, Q99PN2	Gene names	Trim26, Znf173
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173).

TRAF6_HUMAN
NC score	0.110952 (rank : 79)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	136	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

TRI26_HUMAN
NC score	0.110769 (rank : 80)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	136	Target Neighborhood Hits	335	Shared Neighborhood Hits	77
SwissProt Accessions	Q12899	Gene names	TRIM26, RNF95, ZNF173
Domain Architecture
Description	Tripartite motif-containing protein 26 (Zinc finger protein 173) (Acid finger protein) (AFP) (RING finger protein 95).

RO52_MOUSE
NC score	0.110734 (rank : 81)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	136	Target Neighborhood Hits	360	Shared Neighborhood Hits	77
SwissProt Accessions	Q62191	Gene names	Trim21, Ro52, Ssa1
Domain Architecture
Description	52 kDa Ro protein (Sjoegren syndrome type A antigen) (SS-A) (Ro(SS-A)) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (Tripartite motif- containing protein 21).

TRI65_MOUSE
NC score	0.110174 (rank : 82)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	136	Target Neighborhood Hits	340	Shared Neighborhood Hits	76
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRAF6_MOUSE
NC score	0.109142 (rank : 83)	θ value	1.06291 (rank : 83)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	69
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

DTX3_HUMAN
NC score	0.108774 (rank : 84)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	136	Target Neighborhood Hits	198	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N9I9, Q8NAU6, Q8NDS8	Gene names	DTX3
Domain Architecture
Description	Protein deltex-3 (Deltex-3) (Deltex3).

BFAR_HUMAN
NC score	0.107763 (rank : 85)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	136	Target Neighborhood Hits	222	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

TRI48_HUMAN
NC score	0.107713 (rank : 86)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	136	Target Neighborhood Hits	192	Shared Neighborhood Hits	69
SwissProt Accessions	Q8IWZ4, Q9BUW4	Gene names	TRIM48, RNF101
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 48 (RING finger protein 101).

TRI11_HUMAN
NC score	0.107508 (rank : 87)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	136	Target Neighborhood Hits	316	Shared Neighborhood Hits	75
SwissProt Accessions	Q96F44, Q8NCA6, Q9C022	Gene names	TRIM11, RNF92
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-) (RING finger protein 92) (Protein BIA1).

TRI11_MOUSE
NC score	0.107267 (rank : 88)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	136	Target Neighborhood Hits	329	Shared Neighborhood Hits	74
SwissProt Accessions	Q99PQ2, Q8VDX5	Gene names	Trim11
Domain Architecture
Description	Tripartite motif-containing protein 11 (EC 6.3.2.-).

PEX10_HUMAN
NC score	0.107228 (rank : 89)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	74
SwissProt Accessions	O60683, Q5T095, Q9BW90	Gene names	PEX10, RNF69
Domain Architecture
Description	Peroxisome assembly protein 10 (Peroxin-10) (Peroxisome biogenesis factor 10) (RING finger protein 69).

TRI34_HUMAN
NC score	0.106967 (rank : 90)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	136	Target Neighborhood Hits	416	Shared Neighborhood Hits	69
SwissProt Accessions	Q9BYJ4, Q9C016, Q9HCR0, Q9HCR1, Q9HCR2	Gene names	TRIM34, IFP1, RNF21
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34 (Interferon-responsive finger protein 1) (RING finger protein 21).

ZN313_HUMAN
NC score	0.106136 (rank : 91)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	136	Target Neighborhood Hits	264	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y508, Q6N0B0	Gene names	ZNF313, RNF114, ZNF228
Domain Architecture
Description	Zinc finger protein 313 (RING finger protein 114).

TRIM7_MOUSE
NC score	0.106017 (rank : 92)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	136	Target Neighborhood Hits	358	Shared Neighborhood Hits	76
SwissProt Accessions	Q923T7, Q5NCB6, Q99PQ5	Gene names	Trim7, Gnip
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein).

TRI62_MOUSE
NC score	0.104891 (rank : 93)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	136	Target Neighborhood Hits	478	Shared Neighborhood Hits	74
SwissProt Accessions	Q80V85	Gene names	Trim62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRIM8_MOUSE
NC score	0.104834 (rank : 94)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	136	Target Neighborhood Hits	674	Shared Neighborhood Hits	76
SwissProt Accessions	Q99PJ2, Q8C508, Q8C700, Q8CGI2, Q99PQ4	Gene names	Trim8, Gerp, Rnf27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM8_HUMAN
NC score	0.104132 (rank : 95)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	136	Target Neighborhood Hits	650	Shared Neighborhood Hits	76
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

TRIM4_HUMAN
NC score	0.103656 (rank : 96)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	136	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C037, Q96F06, Q9C036	Gene names	TRIM4, RNF87
Domain Architecture
Description	Tripartite motif-containing protein 4 (RING finger protein 87).

TRI65_HUMAN
NC score	0.102104 (rank : 97)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	136	Target Neighborhood Hits	330	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PJ69, Q4G0F0, Q6DKJ6, Q9BRP6	Gene names	TRIM65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

TRI17_HUMAN
NC score	0.100775 (rank : 98)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	136	Target Neighborhood Hits	318	Shared Neighborhood Hits	72
SwissProt Accessions	Q9Y577	Gene names	TRIM17, RBCC, RNF16, TERF
Domain Architecture
Description	Tripartite motif-containing protein 17 (Testis RING finger protein) (RING finger protein 16).

SMRA3_HUMAN
NC score	0.100229 (rank : 99)	θ value	0.279714 (rank : 47)
Query Neighborhood Hits	136	Target Neighborhood Hits	265	Shared Neighborhood Hits	73
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

TRI62_HUMAN
NC score	0.100092 (rank : 100)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	136	Target Neighborhood Hits	584	Shared Neighborhood Hits	73
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

TRI43_HUMAN
NC score	0.099818 (rank : 101)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	136	Target Neighborhood Hits	341	Shared Neighborhood Hits	72
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

TRI56_MOUSE
NC score	0.099567 (rank : 102)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	136	Target Neighborhood Hits	255	Shared Neighborhood Hits	76
SwissProt Accessions	Q80VI1, Q8CAY0	Gene names	Trim56
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56.

TRI34_MOUSE
NC score	0.099546 (rank : 103)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	136	Target Neighborhood Hits	332	Shared Neighborhood Hits	63
SwissProt Accessions	Q99PP6, Q99PP4, Q99PP5	Gene names	Trim34
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 34.

BRCA1_MOUSE
NC score	0.099191 (rank : 104)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	136	Target Neighborhood Hits	436	Shared Neighborhood Hits	72
SwissProt Accessions	P48754, Q60957, Q60983	Gene names	Brca1
Domain Architecture
Description	Breast cancer type 1 susceptibility protein homolog.

TRI17_MOUSE
NC score	0.098844 (rank : 105)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	136	Target Neighborhood Hits	620	Shared Neighborhood Hits	72
SwissProt Accessions	Q7TPM3, Q99PP8	Gene names	Trim17
Domain Architecture
Description	Tripartite motif-containing protein 17.

TRI38_HUMAN
NC score	0.098733 (rank : 106)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	136	Target Neighborhood Hits	373	Shared Neighborhood Hits	75
SwissProt Accessions	O00635	Gene names	TRIM38, RNF15, RORET
Domain Architecture
Description	Tripartite motif-containing protein 38 (RING finger protein 15) (Zinc finger protein RoRet).

NEIL3_HUMAN
NC score	0.098718 (rank : 107)	θ value	0.0961366 (rank : 36)
Query Neighborhood Hits	136	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

TRI27_HUMAN
NC score	0.098435 (rank : 108)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	73
SwissProt Accessions	P14373, Q5ST26, Q6LA73, Q6NXR9, Q9BZY6, Q9UJL3	Gene names	TRIM27, RFP, RNF76
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27) (RING finger protein 76).

TRI54_MOUSE
NC score	0.098102 (rank : 109)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	136	Target Neighborhood Hits	197	Shared Neighborhood Hits	64
SwissProt Accessions	Q9ERP3	Gene names	Trim54, Murf, Rnf30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

TRIM7_HUMAN
NC score	0.097502 (rank : 110)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	136	Target Neighborhood Hits	336	Shared Neighborhood Hits	74
SwissProt Accessions	Q9C029, Q969F5, Q96F67, Q96J89, Q96J90	Gene names	TRIM7, GNIP, RNF90
Domain Architecture
Description	Tripartite motif-containing protein 7 (Glycogenin-interacting protein) (RING finger protein 90).

TRI39_MOUSE
NC score	0.097263 (rank : 111)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	136	Target Neighborhood Hits	691	Shared Neighborhood Hits	77
SwissProt Accessions	Q9ESN2, Q8BPR5, Q8K0F7	Gene names	Trim39, Rnf23, Tfp
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TRI52_HUMAN
NC score	0.096992 (rank : 112)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	136	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q96A61	Gene names	TRIM52, RNF102
Domain Architecture
Description	Tripartite motif-containing protein 52 (RING finger protein 102).

TRI56_HUMAN
NC score	0.096919 (rank : 113)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	136	Target Neighborhood Hits	339	Shared Neighborhood Hits	77
SwissProt Accessions	Q9BRZ2, Q86VT6, Q8N2H8, Q8NAC0, Q9H031	Gene names	TRIM56, RNF109
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 56 (RING finger protein 109).

TRI39_HUMAN
NC score	0.096802 (rank : 114)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	136	Target Neighborhood Hits	693	Shared Neighborhood Hits	77
SwissProt Accessions	Q9HCM9, Q76BL3, Q8IYT9, Q96IB6	Gene names	TRIM39, RNF23, TFP
Domain Architecture
Description	Tripartite motif-containing protein 39 (RING finger protein 23) (Testis-abundant finger protein).

TOPRS_MOUSE
NC score	0.096703 (rank : 115)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	136	Target Neighborhood Hits	263	Shared Neighborhood Hits	56
SwissProt Accessions	Q80Z37, Q3U5B5, Q3UPZ1, Q3USN3, Q3UZ55, Q8BXP2, Q8CFF5, Q8CGC8, Q920L3	Gene names	Topors
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

RFWD2_MOUSE
NC score	0.095612 (rank : 116)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	136	Target Neighborhood Hits	535	Shared Neighborhood Hits	76
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

RFWD2_HUMAN
NC score	0.095551 (rank : 117)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	136	Target Neighborhood Hits	518	Shared Neighborhood Hits	76
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

SMRA3_MOUSE
NC score	0.095482 (rank : 118)	θ value	0.813845 (rank : 69)
Query Neighborhood Hits	136	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

TOPRS_HUMAN
NC score	0.095314 (rank : 119)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	136	Target Neighborhood Hits	286	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NS56, O43273, Q6P987, Q9NS55, Q9UNR9	Gene names	TOPORS, LUN, TP53BPL
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein E3 ligase Topors (EC 6.3.2.-) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3).

TRI49_HUMAN
NC score	0.095309 (rank : 120)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NS80, Q6DJV1	Gene names	TRIM49, RNF18
Domain Architecture
Description	Tripartite motif-containing protein 49 (RING finger protein 18) (Testis-specific ring-finger protein).

TRI27_MOUSE
NC score	0.095293 (rank : 121)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	136	Target Neighborhood Hits	261	Shared Neighborhood Hits	68
SwissProt Accessions	Q62158, Q62157, Q8C2Q5, Q99LK1	Gene names	Trim27, Rfp
Domain Architecture
Description	Zinc finger protein RFP (Ret finger protein) (Tripartite motif- containing protein 27).

BRCA1_HUMAN
NC score	0.095048 (rank : 122)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	136	Target Neighborhood Hits	381	Shared Neighborhood Hits	73
SwissProt Accessions	P38398	Gene names	BRCA1, RNF53
Domain Architecture
Description	Breast cancer type 1 susceptibility protein (RING finger protein 53).

TAB2_MOUSE
NC score	0.094626 (rank : 123)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	136	Target Neighborhood Hits	245	Shared Neighborhood Hits	11
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TRI15_HUMAN
NC score	0.093705 (rank : 124)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	136	Target Neighborhood Hits	395	Shared Neighborhood Hits	66
SwissProt Accessions	Q9C019, O95604, Q8IUX9, Q9C018	Gene names	TRIM15, RNF93, ZNF178, ZNFB7
Domain Architecture
Description	Tripartite motif-containing protein 15 (Zinc finger protein B7) (RING finger protein 93) (Zinc finger protein 178).

TRI60_MOUSE
NC score	0.092606 (rank : 125)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	136	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q8VI40, Q3UX74	Gene names	Trim60, 2czf45, Rnf33
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 60 (Ring finger protein 33).

NEIL3_MOUSE
NC score	0.092553 (rank : 126)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	136	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

TRI54_HUMAN
NC score	0.092142 (rank : 127)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	136	Target Neighborhood Hits	209	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BYV2, Q53SY4, Q9BYV3	Gene names	TRIM54, MURF, MURF3, RNF30
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 54 (Muscle-specific RING finger protein 3) (MuRF3) (MURF-3) (Muscle-specific RING finger protein) (MuRF) (RING finger protein 30).

RNF8_MOUSE
NC score	0.091923 (rank : 128)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	136	Target Neighborhood Hits	618	Shared Neighborhood Hits	80
SwissProt Accessions	Q8VC56, Q9JK13	Gene names	Rnf8
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8) (AIP37) (ActA-interacting protein 37) (LaXp180).

ZN179_HUMAN
NC score	0.090549 (rank : 129)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	136	Target Neighborhood Hits	178	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ULX5, O60633	Gene names	ZNF179, BFP, RNF112
Domain Architecture
Description	Zinc finger protein 179 (Brain finger protein) (RING finger protein 112).

BFAR_MOUSE
NC score	0.089772 (rank : 130)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	136	Target Neighborhood Hits	232	Shared Neighborhood Hits	68
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

TRI55_HUMAN
NC score	0.089396 (rank : 131)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BYV6, Q53XX3, Q8IUD9, Q8IUE4, Q96DV2, Q96DV3, Q9BYV5	Gene names	TRIM55, MURF2, RNF29
Domain Architecture
Description	Tripartite motif-containing protein 55 (Muscle-specific RING finger protein 2) (MuRF2) (MURF-2) (RING finger protein 29).

TAB2_HUMAN
NC score	0.087152 (rank : 132)	θ value	1.06291 (rank : 81)
Query Neighborhood Hits	136	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TRI25_HUMAN
NC score	0.086647 (rank : 133)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	136	Target Neighborhood Hits	472	Shared Neighborhood Hits	79
SwissProt Accessions	Q14258	Gene names	TRIM25, EFP, RNF147, ZNF147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp) (RING finger protein 147).

NPL4_MOUSE
NC score	0.085536 (rank : 134)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	136	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

TRI63_MOUSE
NC score	0.085500 (rank : 135)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	136	Target Neighborhood Hits	240	Shared Neighborhood Hits	60
SwissProt Accessions	Q38HM4, Q8BWC4	Gene names	Trim63, Murf1, Rf1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (Muscle RING finger protein 1).

NPL4_HUMAN
NC score	0.085419 (rank : 136)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	136	Target Neighborhood Hits	19	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

TRI63_HUMAN
NC score	0.085094 (rank : 137)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	136	Target Neighborhood Hits	298	Shared Neighborhood Hits	59
SwissProt Accessions	Q969Q1, Q5T2I1, Q96BD3, Q96KD9, Q9BYV4	Gene names	TRIM63, IRF, MURF1, RNF28, SMRZ
Domain Architecture
Description	Ubiquitin ligase TRIM63 (EC 6.3.2.-) (Tripartite motif-containing protein 63) (Muscle-specific RING finger protein 1) (MuRF1) (MURF-1) (RING finger protein 28) (Striated muscle RING zinc finger protein) (Iris RING finger protein).

TRI41_HUMAN
NC score	0.084449 (rank : 138)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	136	Target Neighborhood Hits	349	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WV44, Q5BKT0, Q7L484, Q96Q10, Q9BSL8	Gene names	TRIM41
Domain Architecture
Description	Tripartite motif-containing protein 41.

TRI25_MOUSE
NC score	0.084346 (rank : 139)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	136	Target Neighborhood Hits	446	Shared Neighborhood Hits	74
SwissProt Accessions	Q61510	Gene names	Trim25, Efp, Zfp147, Znf147
Domain Architecture
Description	Tripartite motif-containing protein 25 (Zinc finger protein 147) (Estrogen-responsive finger protein) (Efp).

RN185_HUMAN
NC score	0.083805 (rank : 140)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	136	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q96GF1, Q8N900	Gene names	RNF185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

RN185_MOUSE
NC score	0.082880 (rank : 141)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	136	Target Neighborhood Hits	211	Shared Neighborhood Hits	71
SwissProt Accessions	Q91YT2, Q6ZWS3	Gene names	Rnf185
Domain Architecture	No domain graphic available
Description	RING finger protein 185.

POK4_HUMAN
NC score	0.082254 (rank : 142)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	136	Target Neighborhood Hits	15	Shared Neighborhood Hits	11
SwissProt Accessions	P63128, Q9UKH4	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_6q14.1 provirus ancestral Pol protein (HERV-K109 Pol protein) (HERV-K(C6) Pol protein).

RNF39_HUMAN
NC score	0.082221 (rank : 143)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	136	Target Neighborhood Hits	200	Shared Neighborhood Hits	67
SwissProt Accessions	Q9H2S5, Q5SPM8, Q5SPM9, Q5SPN0, Q5SRJ9, Q5SRK1, Q5SS29, Q9H2S3, Q9H2S4	Gene names	RNF39, HZFW
Domain Architecture	No domain graphic available
Description	RING finger protein 39 (Protein HZFw).

RNF8_HUMAN
NC score	0.082200 (rank : 144)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	136	Target Neighborhood Hits	622	Shared Neighborhood Hits	77
SwissProt Accessions	O76064	Gene names	RNF8, KIAA0646
Domain Architecture
Description	Ubiquitin ligase protein RNF8 (EC 6.3.2.-) (RING finger protein 8).

POK11_HUMAN
NC score	0.081028 (rank : 145)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	136	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	P87893	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_22q11.21 provirus ancestral Pol protein (HERV-K101 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

RNF41_MOUSE
NC score	0.079763 (rank : 146)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	136	Target Neighborhood Hits	224	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BH75, Q8BGJ2, Q8BMC9, Q8VEA2, Q9CRK6, Q9D568	Gene names	Rnf41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

RNF41_HUMAN
NC score	0.079537 (rank : 147)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	136	Target Neighborhood Hits	226	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H4P4, O75598	Gene names	RNF41
Domain Architecture	No domain graphic available
Description	RING finger protein 41.

TAB3_HUMAN
NC score	0.079350 (rank : 148)	θ value	1.06291 (rank : 82)
Query Neighborhood Hits	136	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TRI37_MOUSE
NC score	0.079126 (rank : 149)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	136	Target Neighborhood Hits	316	Shared Neighborhood Hits	62
SwissProt Accessions	Q6PCX9, Q8CHC5	Gene names	Trim37, Kiaa0898
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37.

RNF5_MOUSE
NC score	0.078521 (rank : 150)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	136	Target Neighborhood Hits	206	Shared Neighborhood Hits	59
SwissProt Accessions	O35445	Gene names	Rnf5, Ng2
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (RING finger protein 5).

RAD18_MOUSE
NC score	0.078164 (rank : 151)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	136	Target Neighborhood Hits	230	Shared Neighborhood Hits	59
SwissProt Accessions	Q9QXK2, Q9CZB8	Gene names	Rad18, Rad18sc
Domain Architecture
Description	Postreplication repair protein RAD18 (mRAD18Sc).

POK7_HUMAN
NC score	0.077877 (rank : 152)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	136	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QC07, Q6QAI9, Q96PI5	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q23.3 provirus ancestral Pol protein (HERV-K18 Pol protein) (HERV-K110 Pol protein) (HERV-K(C1a) Pol protein) [Includes: Reverse transcriptase (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H)].

RNF5_HUMAN
NC score	0.077788 (rank : 153)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	136	Target Neighborhood Hits	206	Shared Neighborhood Hits	60
SwissProt Accessions	Q99942, Q9UMQ2	Gene names	RNF5, G16, NG2, RMA1
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase RMA1 (EC 6.3.2.-) (HsRma1) (RING finger protein 5) (Protein G16).

TRI37_HUMAN
NC score	0.077347 (rank : 154)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	61
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

POK2_HUMAN
NC score	0.077047 (rank : 155)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	136	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXR3, Q6KH04, Q9BXR4, Q9UKH5, Q9UP31, Q9WIK9, Q9WJR4	Gene names	ERVK6
Domain Architecture	No domain graphic available
Description	HERV-K_7p22.1 provirus ancestral Pol protein (HERV-K(HML-2.HOM) Pol protein) (HERV-K108 Pol protein) (HERV-K(C7) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK5_HUMAN
NC score	0.077041 (rank : 156)	θ value	0.813845 (rank : 66)
Query Neighborhood Hits	136	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	P63132	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19p13.11 provirus ancestral Pol protein (HERV-K113 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK17_HUMAN
NC score	0.077038 (rank : 157)	θ value	0.813845 (rank : 62)
Query Neighborhood Hits	136	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	P63136	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_11q22.1 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

POK6_HUMAN
NC score	0.077032 (rank : 158)	θ value	0.813845 (rank : 67)
Query Neighborhood Hits	136	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	P63133	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_8p23.1 provirus ancestral Pol protein (HERV-K115 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

TRI47_MOUSE
NC score	0.073602 (rank : 159)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	136	Target Neighborhood Hits	295	Shared Neighborhood Hits	68
SwissProt Accessions	Q8C0E3, Q6P249, Q811J7, Q8BVZ8, Q8R1K0, Q8R3Y1	Gene names	Trim47
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47.

TRIM1_HUMAN
NC score	0.073512 (rank : 160)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	136	Target Neighborhood Hits	345	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

POK9_HUMAN
NC score	0.073501 (rank : 161)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	136	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	P63134	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_5q13.3 provirus ancestral Pol protein (HERV-K104 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49)].

TRI47_HUMAN
NC score	0.073120 (rank : 162)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	136	Target Neighborhood Hits	286	Shared Neighborhood Hits	69
SwissProt Accessions	Q96LD4, Q96GU5, Q9BRN7	Gene names	TRIM47, GOA, RNF100
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 47 (Gene overexpressed in astrocytoma protein) (RING finger protein 100).

RAD18_HUMAN
NC score	0.072922 (rank : 163)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	136	Target Neighborhood Hits	284	Shared Neighborhood Hits	55
SwissProt Accessions	Q9NS91, Q58F55, Q9NRT6	Gene names	RAD18, RNF73
Domain Architecture
Description	Postreplication repair protein RAD18 (hRAD18) (hHR18) (RING finger protein 73).

RN146_HUMAN
NC score	0.070933 (rank : 164)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	136	Target Neighborhood Hits	162	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NTX7, Q6FIB2, Q7L8H4, Q96K03, Q9NTX6	Gene names	RNF146
Domain Architecture	No domain graphic available
Description	RING finger protein 146 (Dactylidin).

TRIM1_MOUSE
NC score	0.070907 (rank : 165)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	136	Target Neighborhood Hits	361	Shared Neighborhood Hits	72
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

POK3_HUMAN
NC score	0.070086 (rank : 166)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	136	Target Neighborhood Hits	27	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WJR5, O15312	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_19q12 provirus ancestral Pol protein (HERV-K(C19) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

RAG1_HUMAN
NC score	0.069846 (rank : 167)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	136	Target Neighborhood Hits	203	Shared Neighborhood Hits	58
SwissProt Accessions	P15918, Q8NER2	Gene names	RAG1, RNF74
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74).

RN146_MOUSE
NC score	0.069007 (rank : 168)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	136	Target Neighborhood Hits	161	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CZW6, Q3TF93	Gene names	Rnf146
Domain Architecture	No domain graphic available
Description	RING finger protein 146.

MEFV_HUMAN
NC score	0.068252 (rank : 169)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	136	Target Neighborhood Hits	431	Shared Neighborhood Hits	39
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

TAB3_MOUSE
NC score	0.068114 (rank : 170)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	11
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TRI18_HUMAN
NC score	0.067276 (rank : 171)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	136	Target Neighborhood Hits	307	Shared Neighborhood Hits	71
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI18_MOUSE
NC score	0.066861 (rank : 172)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	136	Target Neighborhood Hits	292	Shared Neighborhood Hits	70
SwissProt Accessions	O70583, O35418, Q7TPT6	Gene names	Mid1, Fxy, Trim18
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Midin).

POK20_HUMAN
NC score	0.066242 (rank : 173)	θ value	0.813845 (rank : 63)
Query Neighborhood Hits	136	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UQG0, Q6KH06, Q86YP3	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_3q27.3 provirus ancestral Pol protein [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

MEFV_MOUSE
NC score	0.064285 (rank : 174)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	136	Target Neighborhood Hits	236	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JJ26	Gene names	Mefv
Domain Architecture
Description	Pyrin (Marenostrin).

TRIM9_MOUSE
NC score	0.064183 (rank : 175)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	136	Target Neighborhood Hits	274	Shared Neighborhood Hits	63
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

RAG1_MOUSE
NC score	0.064029 (rank : 176)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	136	Target Neighborhood Hits	189	Shared Neighborhood Hits	56
SwissProt Accessions	P15919	Gene names	Rag1, Rag-1
Domain Architecture
Description	V(D)J recombination-activating protein 1 (RAG-1).

TRIM9_HUMAN
NC score	0.063654 (rank : 177)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	136	Target Neighborhood Hits	294	Shared Neighborhood Hits	63
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

RN141_HUMAN
NC score	0.063580 (rank : 178)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	136	Target Neighborhood Hits	199	Shared Neighborhood Hits	62
SwissProt Accessions	Q8WVD5, Q9NZB4	Gene names	RNF141, ZNF230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

RN141_MOUSE
NC score	0.063305 (rank : 179)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	136	Target Neighborhood Hits	200	Shared Neighborhood Hits	62
SwissProt Accessions	Q99MB7, Q9D040, Q9D5C4, Q9D9L0	Gene names	Rnf141, Znf230
Domain Architecture	No domain graphic available
Description	RING finger protein 141 (Zinc finger protein 230).

PCGF4_HUMAN
NC score	0.063088 (rank : 180)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	136	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	P35226, Q16030, Q96F37	Gene names	PCGF4, BMI1, RNF51
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1) (RING finger protein 51).

PCGF4_MOUSE
NC score	0.063032 (rank : 181)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	136	Target Neighborhood Hits	163	Shared Neighborhood Hits	53
SwissProt Accessions	P25916	Gene names	Pcgf4, Bmi-1, Bmi1
Domain Architecture
Description	Polycomb group RING finger protein 4 (Polycomb complex protein BMI-1).

RFPL3_HUMAN
NC score	0.062759 (rank : 182)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	136	Target Neighborhood Hits	134	Shared Neighborhood Hits	48
SwissProt Accessions	O75679, Q6IC04	Gene names	RFPL3
Domain Architecture
Description	Ret finger protein-like 3.

PML_MOUSE
NC score	0.061851 (rank : 183)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	136	Target Neighborhood Hits	246	Shared Neighborhood Hits	51
SwissProt Accessions	Q60953	Gene names	Pml
Domain Architecture	No domain graphic available
Description	Probable transcription factor PML.

TRI14_HUMAN
NC score	0.061297 (rank : 184)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	136	Target Neighborhood Hits	143	Shared Neighborhood Hits	34
SwissProt Accessions	Q14142, Q9BRD8, Q9C020	Gene names	TRIM14, KIAA0129
Domain Architecture
Description	Tripartite motif-containing protein 14.

PCGF2_HUMAN
NC score	0.060649 (rank : 185)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	136	Target Neighborhood Hits	222	Shared Neighborhood Hits	52
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PCGF2_MOUSE
NC score	0.060585 (rank : 186)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	136	Target Neighborhood Hits	213	Shared Neighborhood Hits	52
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

DTX3L_HUMAN
NC score	0.060104 (rank : 187)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	136	Target Neighborhood Hits	187	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDB6	Gene names	DTX3L, BBAP
Domain Architecture
Description	Protein deltex 3-like protein (B-lymphoma- and BAL-associated protein) (Rhysin-2) (Rhysin2).

TRAF3_HUMAN
NC score	0.059638 (rank : 188)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	136	Target Neighborhood Hits	463	Shared Neighborhood Hits	55
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

TRI14_MOUSE
NC score	0.059474 (rank : 189)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	136	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BVW3, Q6A0C3, Q762I6, Q9D3G8	Gene names	Trim14, Kiaa0129, Pub
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 14 (PU.1-binding protein).

TRI44_MOUSE
NC score	0.058821 (rank : 190)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	136	Target Neighborhood Hits	327	Shared Neighborhood Hits	31
SwissProt Accessions	Q9QXA7, Q80SV9, Q9JHR8	Gene names	Trim44, Dipb
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB) (Protein Mc7).

TRI44_HUMAN
NC score	0.058469 (rank : 191)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	136	Target Neighborhood Hits	393	Shared Neighborhood Hits	31
SwissProt Accessions	Q96DX7, Q96QY2, Q9UGK0	Gene names	TRIM44, DIPB
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 44 (Protein DIPB).

NHLC1_HUMAN
NC score	0.057813 (rank : 192)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	136	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	Q6VVB1, Q6IMH1	Gene names	NHLRC1, EPM2B
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

RFPL2_HUMAN
NC score	0.057172 (rank : 193)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	136	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	O75678	Gene names	RFPL2, RNF79
Domain Architecture
Description	Ret finger protein-like 2 (RING finger protein 79).

POK10_HUMAN
NC score	0.057055 (rank : 194)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	136	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	P10266, P87890, Q14273	Gene names
Domain Architecture
Description	HERV-K_5q33.3 provirus ancestral Pol protein (HERV-K10 Pol protein) (HERV-K107 Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

PML_HUMAN
NC score	0.057008 (rank : 195)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	136	Target Neighborhood Hits	248	Shared Neighborhood Hits	50
SwissProt Accessions	P29590, P29591, P29592, P29593, Q00755	Gene names	PML, MYL, RNF71, TRIM19
Domain Architecture
Description	Probable transcription factor PML (Tripartite motif-containing protein 19) (RING finger protein 71).

RFPL1_HUMAN
NC score	0.056790 (rank : 196)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	136	Target Neighborhood Hits	119	Shared Neighborhood Hits	39
SwissProt Accessions	O75677, Q6IC06	Gene names	RFPL1, RFPL1L, RNF78
Domain Architecture
Description	Ret finger protein-like 1 (RING finger protein 78).

TRI46_MOUSE
NC score	0.056485 (rank : 197)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	136	Target Neighborhood Hits	287	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI29_MOUSE
NC score	0.056009 (rank : 198)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	136	Target Neighborhood Hits	306	Shared Neighborhood Hits	35
SwissProt Accessions	Q8R2Q0, Q8CEE2, Q922Y3, Q99PN5, Q9CSC9	Gene names	Trim29
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29.

MNAB_HUMAN
NC score	0.055106 (rank : 199)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	136	Target Neighborhood Hits	196	Shared Neighborhood Hits	49
SwissProt Accessions	Q9HBD1, Q5JPD7, Q86ST6, Q8N3D6, Q96F27, Q9H5J2, Q9HBD2, Q9NWN9, Q9NXE1	Gene names	MNAB, RNF164
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein (RING finger protein 164).

TRI46_HUMAN
NC score	0.055072 (rank : 200)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	136	Target Neighborhood Hits	291	Shared Neighborhood Hits	63
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

NHLC1_MOUSE
NC score	0.055006 (rank : 201)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	136	Target Neighborhood Hits	103	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BR37	Gene names	Nhlrc1, Epm2b
Domain Architecture	No domain graphic available
Description	NHL repeat-containing protein 1 (Malin).

TRI42_MOUSE
NC score	0.054836 (rank : 202)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	136	Target Neighborhood Hits	316	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RN169_HUMAN
NC score	0.054771 (rank : 203)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	136	Target Neighborhood Hits	203	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NCN4, Q6N015	Gene names	RNF169, KIAA1991
Domain Architecture	No domain graphic available
Description	RING finger protein 169.

TRI36_HUMAN
NC score	0.054759 (rank : 204)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	136	Target Neighborhood Hits	282	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

TRI45_HUMAN
NC score	0.054207 (rank : 205)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H8W5, Q5T2K4, Q5T2K5, Q8IYV6	Gene names	TRIM45, RNF99
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 45 (RING finger protein 99).

MNAB_MOUSE
NC score	0.054002 (rank : 206)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	136	Target Neighborhood Hits	231	Shared Neighborhood Hits	48
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

RNF32_MOUSE
NC score	0.053864 (rank : 207)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	136	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	Q9JIT1, Q9D9X0, Q9DAJ3	Gene names	Rnf32, Lmbr2
Domain Architecture	No domain graphic available
Description	RING finger protein 32 (Limb region protein 2).

POK12_HUMAN
NC score	0.053552 (rank : 208)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	136	Target Neighborhood Hits	50	Shared Neighborhood Hits	11
SwissProt Accessions	P63135	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Pol protein (HERV-K102 Pol protein) (HERV-K(III) Pol protein) [Includes: Reverse transcriptase (RT) (EC 2.7.7.49); Ribonuclease H (EC 3.1.26.4) (RNase H); Integrase (IN)].

ERMAP_HUMAN
NC score	0.052770 (rank : 209)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	136	Target Neighborhood Hits	155	Shared Neighborhood Hits	21
SwissProt Accessions	Q96PL5, Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3, Q96PL6	Gene names	ERMAP, RD, SC
Domain Architecture	No domain graphic available
Description	Erythroid membrane-associated protein precursor (hERMAP) (Scianna blood group antigen) (Radin blood group antigen).

TRI36_MOUSE
NC score	0.052170 (rank : 210)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	136	Target Neighborhood Hits	266	Shared Neighborhood Hits	50
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

BSPRY_MOUSE
NC score	0.051775 (rank : 211)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	136	Target Neighborhood Hits	163	Shared Neighborhood Hits	30
SwissProt Accessions	Q80YW5, Q3TU74, Q8BZF0, Q99KV7, Q9ER70	Gene names	Bspry
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

TRAF4_HUMAN
NC score	0.051388 (rank : 212)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	136	Target Neighborhood Hits	373	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRI29_HUMAN
NC score	0.051177 (rank : 213)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	136	Target Neighborhood Hits	273	Shared Neighborhood Hits	33
SwissProt Accessions	Q14134, Q96AA9, Q9BZY7	Gene names	TRIM29, ATDC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 29 (Ataxia-telangiectasia group D- associated protein).

UHRF2_HUMAN
NC score	0.050891 (rank : 214)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	136	Target Neighborhood Hits	269	Shared Neighborhood Hits	67
SwissProt Accessions	Q96PU4, Q5VYR1, Q5VYR3, Q659C8, Q8TAG7	Gene names	UHRF2, NIRF, RNF107
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 2 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 2) (Np95/ICBP90-like RING finger protein) (Np95-like RING finger protein) (Nuclear zinc finger protein Np97) (RING finger protein 107).

BSPRY_HUMAN
NC score	0.050676 (rank : 215)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	136	Target Neighborhood Hits	115	Shared Neighborhood Hits	30
SwissProt Accessions	Q5W0U4, Q96DJ2, Q9H4E4, Q9NXN0	Gene names	BSPRY
Domain Architecture	No domain graphic available
Description	B box and SPRY domain-containing protein.

RNF32_HUMAN
NC score	0.050343 (rank : 216)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	136	Target Neighborhood Hits	133	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H0A6, Q6FIB3, Q6X7T4, Q8N6V8, Q8TDG0, Q96BM5, Q9Y6U1	Gene names	RNF32
Domain Architecture	No domain graphic available
Description	RING finger protein 32.

P2RX7_HUMAN
NC score	0.043189 (rank : 217)	θ value	0.0252991 (rank : 26)
Query Neighborhood Hits	136	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q99572, O14991, Q96EV7	Gene names	P2RX7
Domain Architecture
Description	P2X purinoceptor 7 (ATP receptor) (P2X7) (Purinergic receptor) (P2Z receptor).

HLF_HUMAN
NC score	0.043090 (rank : 218)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	136	Target Neighborhood Hits	75	Shared Neighborhood Hits	5
SwissProt Accessions	Q16534	Gene names	HLF
Domain Architecture
Description	Hepatic leukemia factor.

HLF_MOUSE
NC score	0.043081 (rank : 219)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	136	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BW74, Q6PF83	Gene names	Hlf
Domain Architecture	No domain graphic available
Description	Hepatic leukemia factor.

BRE1B_MOUSE
NC score	0.041652 (rank : 220)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	136	Target Neighborhood Hits	970	Shared Neighborhood Hits	64
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

BRE1B_HUMAN
NC score	0.040146 (rank : 221)	θ value	1.81305 (rank : 88)
Query Neighborhood Hits	136	Target Neighborhood Hits	1040	Shared Neighborhood Hits	64
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

PKHA6_MOUSE
NC score	0.034785 (rank : 222)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	136	Target Neighborhood Hits	591	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RN165_HUMAN
NC score	0.034783 (rank : 223)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	136	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZSG1	Gene names	RNF165
Domain Architecture	No domain graphic available
Description	RING finger protein 165.

PKHA6_HUMAN
NC score	0.034634 (rank : 224)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	136	Target Neighborhood Hits	556	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

KI67_HUMAN
NC score	0.031686 (rank : 225)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	136	Target Neighborhood Hits	581	Shared Neighborhood Hits	6
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

AB1IP_MOUSE
NC score	0.026977 (rank : 226)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	136	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

TULP4_HUMAN
NC score	0.024119 (rank : 227)	θ value	0.813845 (rank : 72)
Query Neighborhood Hits	136	Target Neighborhood Hits	426	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NRJ4, Q9HD22, Q9P2F0	Gene names	TULP4, KIAA1397, TUSP
Domain Architecture
Description	Tubby-like protein 4 (Tubby superfamily protein).

COMP_MOUSE
NC score	0.009618 (rank : 228)	θ value	3.0926 (rank : 101)
Query Neighborhood Hits	136	Target Neighborhood Hits	290	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

TAF4_HUMAN
NC score	0.006993 (rank : 229)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	136	Target Neighborhood Hits	687	Shared Neighborhood Hits	7
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

SEM6B_HUMAN
NC score	0.003762 (rank : 230)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	136	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

BOC_HUMAN
NC score	0.003137 (rank : 231)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	136	Target Neighborhood Hits	543	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

NKX31_MOUSE
NC score	0.001189 (rank : 232)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	136	Target Neighborhood Hits	379	Shared Neighborhood Hits	2
SwissProt Accessions	P97436, O09087	Gene names	Nkx3-1, Nkx-3.1, Nkx3a
Domain Architecture
Description	Homeobox protein Nkx-3.1.

ZN553_HUMAN
NC score	0.000336 (rank : 233)	θ value	1.06291 (rank : 84)
Query Neighborhood Hits	136	Target Neighborhood Hits	760	Shared Neighborhood Hits	6
SwissProt Accessions	Q96MX3, Q4G0R3, Q69YP3, Q96IL9	Gene names	ZNF553
Domain Architecture	No domain graphic available
Description	Zinc finger protein 553.

ZN406_HUMAN
NC score	-0.000929 (rank : 234)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	136	Target Neighborhood Hits	794	Shared Neighborhood Hits	7
SwissProt Accessions	Q9P243, Q3MIM5, Q6PJ01, Q75PJ7, Q75PJ9, Q86X64	Gene names	ZNF406, KIAA1485
Domain Architecture	No domain graphic available
Description	Zinc finger protein 406 (Protein ZFAT).

ZN306_HUMAN
NC score	-0.002396 (rank : 235)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	136	Target Neighborhood Hits	757	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BRR0, Q5VXH3, Q92972, Q9H4T3	Gene names	ZNF306, ZFP47, ZSCAN13
Domain Architecture
Description	Zinc finger protein 306 (Zinc finger protein 47 homolog) (Zfp-47) (Zf47) (Zinc finger and SCAN domain-containing protein 13).