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Network neighborhood for query Sequence : NEIL3_HUMAN

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NEIL3_HUMAN
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NEIL3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_MOUSE
θ value	0 (rank : 2)	NC score	0.982026 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

TOP3A_HUMAN
θ value	8.11959e-09 (rank : 3)	NC score	0.324149 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

TOP3A_MOUSE
θ value	8.11959e-09 (rank : 4)	NC score	0.324858 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

NEIL2_HUMAN
θ value	1.38499e-08 (rank : 5)	NC score	0.416445 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q969S2, Q7Z3Q7, Q8N842, Q8NG52	Gene names	NEIL2
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2).

NEIL2_MOUSE
θ value	1.29631e-06 (rank : 6)	NC score	0.377095 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R2P8	Gene names	Neil2
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2).

APEX2_MOUSE
θ value	6.43352e-06 (rank : 7)	NC score	0.319748 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

APEX2_HUMAN
θ value	2.44474e-05 (rank : 8)	NC score	0.307134 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

RBP2_HUMAN
θ value	0.000158464 (rank : 9)	NC score	0.096930 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

TTF2_MOUSE
θ value	0.000786445 (rank : 10)	NC score	0.116157 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	364	Shared Neighborhood Hits	8
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

TTF2_HUMAN
θ value	0.00298849 (rank : 11)	NC score	0.105243 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

ZRAN1_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.149190 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

RBP2_MOUSE
θ value	0.0193708 (rank : 13)	NC score	0.089928 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

UB7I3_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.098718 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

CASC5_MOUSE
θ value	0.163984 (rank : 15)	NC score	0.059019 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

UB7I3_MOUSE
θ value	0.21417 (rank : 16)	NC score	0.091203 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

USP9X_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.040854 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9X_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.041046 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

IF4G3_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.030808 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ABCA4_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.016016 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

FANCJ_MOUSE
θ value	0.62314 (rank : 21)	NC score	0.035882 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

UBAP1_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.041177 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

ZCHC4_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.093358 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5U6, Q5IW78, Q96AN7	Gene names	ZCCHC4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

ZCHC4_MOUSE
θ value	1.06291 (rank : 24)	NC score	0.111218 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKW4, Q3UTX6, Q9D2I1	Gene names	Zcchc4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

ELK3_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.013290 (rank : 46)
Query Neighborhood Hits	41	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

MBD1_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.023075 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

NU153_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.082063 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

TAB3_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.027645 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	273	Shared Neighborhood Hits	10
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TARA_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.007205 (rank : 47)
Query Neighborhood Hits	41	Target Neighborhood Hits	1626	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

JHD1B_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.014762 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.014750 (rank : 45)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

MDM4_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.032783 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MDM4_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.034807 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

MK08_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.000350 (rank : 50)
Query Neighborhood Hits	41	Target Neighborhood Hits	834	Shared Neighborhood Hits	3
SwissProt Accessions	P45983, Q15709, Q15712, Q15713	Gene names	MAPK8, JNK1, PRKM8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46).

PTPRO_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.005711 (rank : 48)
Query Neighborhood Hits	41	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

RYBP_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.034313 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

SNPC4_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.014767 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

WNK1_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.001148 (rank : 49)
Query Neighborhood Hits	41	Target Neighborhood Hits	1158	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

K0423_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.018845 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

K0423_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.019350 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

TAB3_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.024639 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	168	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

NEIL1_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.079399 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FI4, Q6ZRA7, Q86XW7, Q9H6C3	Gene names	NEIL1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1) (FPG1).

NEIL1_MOUSE
θ value	θ > 10 (rank : 43)	NC score	0.058258 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

RANG_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.050601 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

RANG_MOUSE
θ value	θ > 10 (rank : 45)	NC score	0.050985 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RBP22_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.052856 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RBP26_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.053049 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RGPD8_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.052999 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

TOP3B_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.104820 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O95985, Q9BUP5	Gene names	TOP3B, TOP3B1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

TOP3B_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.105161 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z321	Gene names	Top3b, Top3b1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

Hits sorted by NC score

NEIL3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_MOUSE
NC score	0.982026 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL2_HUMAN
NC score	0.416445 (rank : 3)	θ value	1.38499e-08 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	4
SwissProt Accessions	Q969S2, Q7Z3Q7, Q8N842, Q8NG52	Gene names	NEIL2
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2).

NEIL2_MOUSE
NC score	0.377095 (rank : 4)	θ value	1.29631e-06 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q6R2P8	Gene names	Neil2
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 2 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 2) (DNA glycosylase/AP lyase Neil2) (DNA-(apurinic or apyrimidinic site) lyase Neil2) (NEH2).

TOP3A_MOUSE
NC score	0.324858 (rank : 5)	θ value	8.11959e-09 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

TOP3A_HUMAN
NC score	0.324149 (rank : 6)	θ value	8.11959e-09 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

APEX2_MOUSE
NC score	0.319748 (rank : 7)	θ value	6.43352e-06 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

APEX2_HUMAN
NC score	0.307134 (rank : 8)	θ value	2.44474e-05 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

ZRAN1_HUMAN
NC score	0.149190 (rank : 9)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

TTF2_MOUSE
NC score	0.116157 (rank : 10)	θ value	0.000786445 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	364	Shared Neighborhood Hits	8
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ZCHC4_MOUSE
NC score	0.111218 (rank : 11)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BKW4, Q3UTX6, Q9D2I1	Gene names	Zcchc4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

TTF2_HUMAN
NC score	0.105243 (rank : 12)	θ value	0.00298849 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	98	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TOP3B_MOUSE
NC score	0.105161 (rank : 13)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	41	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z321	Gene names	Top3b, Top3b1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

TOP3B_HUMAN
NC score	0.104820 (rank : 14)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	O95985, Q9BUP5	Gene names	TOP3B, TOP3B1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

UB7I3_HUMAN
NC score	0.098718 (rank : 15)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	136	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYM8, O95623, Q96BS3, Q9BYM9	Gene names	RBCK1, C20orf18, RNF54, UBCE7IP3, XAP4
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (Hepatitis B virus X- associated protein 4) (HBV-associated factor 4) (RING finger protein 54).

RBP2_HUMAN
NC score	0.096930 (rank : 16)	θ value	0.000158464 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

ZCHC4_HUMAN
NC score	0.093358 (rank : 17)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H5U6, Q5IW78, Q96AN7	Gene names	ZCCHC4
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 4.

UB7I3_MOUSE
NC score	0.091203 (rank : 18)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	131	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WUB0	Gene names	Rbck1, Rbck, Ubce7ip3, Uip28
Domain Architecture
Description	RanBP-type and C3HC4-type zinc finger-containing protein 1 (Ubiquitin- conjugating enzyme 7-interacting protein 3) (UbcM4-interacting protein 28).

RBP2_MOUSE
NC score	0.089928 (rank : 19)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	232	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

NU153_HUMAN
NC score	0.082063 (rank : 20)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

NEIL1_HUMAN
NC score	0.079399 (rank : 21)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	Q96FI4, Q6ZRA7, Q86XW7, Q9H6C3	Gene names	NEIL1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1) (FPG1).

CASC5_MOUSE
NC score	0.059019 (rank : 22)	θ value	0.163984 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q66JQ7, Q8CCH6, Q9CV38	Gene names	Casc5
Domain Architecture	No domain graphic available
Description	Protein CASC5 (Cancer susceptibility candidate gene 5 protein homolog).

NEIL1_MOUSE
NC score	0.058258 (rank : 23)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4Q6, Q80V58, Q9CYT9	Gene names	Neil1, Nei1
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 1 (EC 3.2.2.-) (EC 4.2.99.18) (Nei-like 1) (DNA glycosylase/AP lyase Neil1) (DNA-(apurinic or apyrimidinic site) lyase Neil1) (NEH1).

RBP26_HUMAN
NC score	0.053049 (rank : 24)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	41	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RGPD8_HUMAN
NC score	0.052999 (rank : 25)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	41	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

RBP22_HUMAN
NC score	0.052856 (rank : 26)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	41	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RANG_MOUSE
NC score	0.050985 (rank : 27)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RANG_HUMAN
NC score	0.050601 (rank : 28)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

UBAP1_HUMAN
NC score	0.041177 (rank : 29)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NZ09, Q4V759, Q5T7B3, Q6FI75, Q8NC52, Q8NCG6, Q8NCH9	Gene names	UBAP1
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 1 (UBAP).

USP9X_MOUSE
NC score	0.041046 (rank : 30)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

USP9X_HUMAN
NC score	0.040854 (rank : 31)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	161	Shared Neighborhood Hits	3
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

FANCJ_MOUSE
NC score	0.035882 (rank : 32)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SXJ3, Q8BJQ8, Q8BKI6	Gene names	Brip1, Bach1, Fancj
Domain Architecture	No domain graphic available
Description	Fanconi anemia group J protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase BRIP1) (Protein FACJ) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1) (BRCA1-associated C-terminal helicase 1).

MDM4_MOUSE
NC score	0.034807 (rank : 33)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O35618	Gene names	Mdm4, Mdmx
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

RYBP_HUMAN
NC score	0.034313 (rank : 34)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

MDM4_HUMAN
NC score	0.032783 (rank : 35)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	O15151, Q6GS18, Q8IV83	Gene names	MDM4, MDMX
Domain Architecture
Description	Mdm4 protein (p53-binding protein Mdm4) (Mdm2-like p53-binding protein) (Mdmx protein) (Double minute 4 protein).

IF4G3_MOUSE
NC score	0.030808 (rank : 36)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	279	Shared Neighborhood Hits	2
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

TAB3_MOUSE
NC score	0.027645 (rank : 37)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	273	Shared Neighborhood Hits	10
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

TAB3_HUMAN
NC score	0.024639 (rank : 38)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	168	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

MBD1_MOUSE
NC score	0.023075 (rank : 39)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2E2, Q792D6, Q8CCL9, Q9DC19	Gene names	Mbd1
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 1 (Methyl-CpG-binding protein MBD1).

K0423_MOUSE
NC score	0.019350 (rank : 40)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

K0423_HUMAN
NC score	0.018845 (rank : 41)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	171	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4F4, Q68D66, Q6PG27	Gene names	KIAA0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

ABCA4_HUMAN
NC score	0.016016 (rank : 42)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	116	Shared Neighborhood Hits	2
SwissProt Accessions	P78363, O15112, O60438, O60915	Gene names	ABCA4, ABCR
Domain Architecture
Description	Retinal-specific ATP-binding cassette transporter (ATP-binding cassette sub-family A member 4) (RIM ABC transporter) (RIM protein) (RmP) (Stargardt disease protein).

SNPC4_MOUSE
NC score	0.014767 (rank : 43)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	237	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

JHD1B_HUMAN
NC score	0.014762 (rank : 44)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NHM5, Q8NCI2, Q96HC7, Q96SL0, Q96T03, Q9NS96, Q9UF75	Gene names	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10) (Protein JEMMA) (Jumonji domain-containing EMSY-interactor methyltransferase motif protein) (CXXC-type zinc finger protein 2) (Protein-containing CXXC domain 2).

JHD1B_MOUSE
NC score	0.014750 (rank : 45)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

ELK3_MOUSE
NC score	0.013290 (rank : 46)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	72	Shared Neighborhood Hits	2
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

TARA_HUMAN
NC score	0.007205 (rank : 47)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	1626	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

PTPRO_HUMAN
NC score	0.005711 (rank : 48)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	139	Shared Neighborhood Hits	2
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

WNK1_HUMAN
NC score	0.001148 (rank : 49)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	1158	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

MK08_HUMAN
NC score	0.000350 (rank : 50)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	834	Shared Neighborhood Hits	3
SwissProt Accessions	P45983, Q15709, Q15712, Q15713	Gene names	MAPK8, JNK1, PRKM8
Domain Architecture
Description	Mitogen-activated protein kinase 8 (EC 2.7.11.24) (Stress-activated protein kinase JNK1) (c-Jun N-terminal kinase 1) (JNK-46).