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Network neighborhood for query Sequence : TOP3B_MOUSE

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TOP3B_MOUSE
SwissProt Accessions	Q9Z321	Gene names	Top3b, Top3b1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TOP3B_HUMAN
θ value	0 (rank : 1)	NC score	0.998789 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	O95985, Q9BUP5	Gene names	TOP3B, TOP3B1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

TOP3B_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z321	Gene names	Top3b, Top3b1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

TOP3A_MOUSE
θ value	1.02895e-112 (rank : 3)	NC score	0.890109 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

TOP3A_HUMAN
θ value	3.91003e-112 (rank : 4)	NC score	0.891080 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

TENA_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.008658 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	631	Shared Neighborhood Hits	3
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

CL025_HUMAN
θ value	5.27518 (rank : 6)	NC score	0.021129 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

MLL2_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.009829 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	1788	Shared Neighborhood Hits	4
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FUCO2_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.011768 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BTY2, Q7Z6Y2, Q8NBK4	Gene names	FUCA2
Domain Architecture	No domain graphic available
Description	Plasma alpha-L-fucosidase precursor (EC 3.2.1.51) (Alpha-L-fucosidase 2) (Alpha-L-fucoside fucohydrolase 2).

LRP2_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.005096 (rank : 14)
Query Neighborhood Hits	11	Target Neighborhood Hits	573	Shared Neighborhood Hits	3
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

RHG12_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.006678 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

ZN578_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.000263 (rank : 15)
Query Neighborhood Hits	11	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N58	Gene names	ZNF578
Domain Architecture	No domain graphic available
Description	Zinc finger protein 578.

APEX2_HUMAN
θ value	θ > 10 (rank : 12)	NC score	0.074399 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

APEX2_MOUSE
θ value	θ > 10 (rank : 13)	NC score	0.078473 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

NEIL3_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.105161 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.113250 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

Hits sorted by NC score

TOP3B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z321	Gene names	Top3b, Top3b1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

TOP3B_HUMAN
NC score	0.998789 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	O95985, Q9BUP5	Gene names	TOP3B, TOP3B1
Domain Architecture
Description	DNA topoisomerase 3-beta-1 (EC 5.99.1.2) (DNA topoisomerase III beta- 1).

TOP3A_HUMAN
NC score	0.891080 (rank : 3)	θ value	3.91003e-112 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q13472, Q13473	Gene names	TOP3A, TOP3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

TOP3A_MOUSE
NC score	0.890109 (rank : 4)	θ value	1.02895e-112 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	O70157	Gene names	Top3a, Top3
Domain Architecture
Description	DNA topoisomerase 3-alpha (EC 5.99.1.2) (DNA topoisomerase III alpha).

NEIL3_MOUSE
NC score	0.113250 (rank : 5)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	11	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_HUMAN
NC score	0.105161 (rank : 6)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	11	Target Neighborhood Hits	41	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

APEX2_MOUSE
NC score	0.078473 (rank : 7)	θ value	θ > 10 (rank : 13)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q68G58, Q8BJP7, Q8BTR7, Q8BUZ2, Q8BYE9, Q8R018, Q8R328, Q9CS12	Gene names	Apex2, Ape2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2).

APEX2_HUMAN
NC score	0.074399 (rank : 8)	θ value	θ > 10 (rank : 12)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBZ4, Q9Y5X7	Gene names	APEX2, APE2, APEXL2, XTH2
Domain Architecture	No domain graphic available
Description	DNA-(apurinic or apyrimidinic site) lyase 2 (EC 4.2.99.18) (Apurinic- apyrimidinic endonuclease 2) (AP endonuclease 2) (APEX nuclease 2) (APEX nuclease-like 2) (AP endonuclease XTH2).

CL025_HUMAN
NC score	0.021129 (rank : 9)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	179	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IYM0, Q8TCP7, Q9H0L3	Gene names	C12orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf25.

FUCO2_HUMAN
NC score	0.011768 (rank : 10)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BTY2, Q7Z6Y2, Q8NBK4	Gene names	FUCA2
Domain Architecture	No domain graphic available
Description	Plasma alpha-L-fucosidase precursor (EC 3.2.1.51) (Alpha-L-fucosidase 2) (Alpha-L-fucoside fucohydrolase 2).

MLL2_HUMAN
NC score	0.009829 (rank : 11)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	1788	Shared Neighborhood Hits	4
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

TENA_HUMAN
NC score	0.008658 (rank : 12)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	631	Shared Neighborhood Hits	3
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

RHG12_MOUSE
NC score	0.006678 (rank : 13)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

LRP2_HUMAN
NC score	0.005096 (rank : 14)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	573	Shared Neighborhood Hits	3
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

ZN578_HUMAN
NC score	0.000263 (rank : 15)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	755	Shared Neighborhood Hits	3
SwissProt Accessions	Q96N58	Gene names	ZNF578
Domain Architecture	No domain graphic available
Description	Zinc finger protein 578.