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Network neighborhood for query Sequence : ZRAN1_HUMAN

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ZRAN1_HUMAN
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZRAN1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

TNAP3_MOUSE
θ value	4.89182e-30 (rank : 2)	NC score	0.707938 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

TNAP3_HUMAN
θ value	8.3442e-30 (rank : 3)	NC score	0.701019 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

OTU7B_HUMAN
θ value	3.87602e-27 (rank : 4)	NC score	0.679850 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

OTU7A_HUMAN
θ value	1.24688e-25 (rank : 5)	NC score	0.684976 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7A_MOUSE
θ value	1.62847e-25 (rank : 6)	NC score	0.680726 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

RBP2_MOUSE
θ value	6.00763e-12 (rank : 7)	NC score	0.196760 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	232	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RBP2_HUMAN
θ value	1.25267e-09 (rank : 8)	NC score	0.191855 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	249	Shared Neighborhood Hits	16
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

NU153_HUMAN
θ value	3.64472e-09 (rank : 9)	NC score	0.319819 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

RNF31_HUMAN
θ value	1.43324e-05 (rank : 10)	NC score	0.231959 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
θ value	1.87187e-05 (rank : 11)	NC score	0.227783 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

NEIL3_MOUSE
θ value	0.00869519 (rank : 12)	NC score	0.150177 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_HUMAN
θ value	0.0148317 (rank : 13)	NC score	0.149190 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

TAB2_MOUSE
θ value	0.0563607 (rank : 14)	NC score	0.131888 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	245	Shared Neighborhood Hits	17
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

TAB2_HUMAN
θ value	0.0736092 (rank : 15)	NC score	0.136584 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

YAF2_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.190989 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY57, Q99710	Gene names	YAF2
Domain Architecture
Description	YY1-associated factor 2.

YAF2_MOUSE
θ value	0.0736092 (rank : 17)	NC score	0.195626 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

RYBP_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.176625 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

RYBP_MOUSE
θ value	0.163984 (rank : 19)	NC score	0.173368 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

ZRAB2_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.112546 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

TAB3_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.118010 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

R113B_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.068405 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

SPN90_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.062974 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

TAB3_MOUSE
θ value	0.47712 (rank : 24)	NC score	0.114005 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	273	Shared Neighborhood Hits	15
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

MYH14_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.009955 (rank : 66)
Query Neighborhood Hits	44	Target Neighborhood Hits	1225	Shared Neighborhood Hits	4
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

NPL4_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.084066 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.084139 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

R113A_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.060321 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

SPN90_HUMAN
θ value	1.06291 (rank : 29)	NC score	0.057117 (rank : 49)
Query Neighborhood Hits	44	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

EVPL_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.013696 (rank : 65)
Query Neighborhood Hits	44	Target Neighborhood Hits	895	Shared Neighborhood Hits	4
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

SRGP2_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.024854 (rank : 56)
Query Neighborhood Hits	44	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	2.36792 (rank : 32)	NC score	0.025135 (rank : 55)
Query Neighborhood Hits	44	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

MYH14_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.008977 (rank : 68)
Query Neighborhood Hits	44	Target Neighborhood Hits	995	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ELOA2_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.023174 (rank : 57)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

SRGP1_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.022083 (rank : 58)
Query Neighborhood Hits	44	Target Neighborhood Hits	390	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

UDA1_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.007267 (rank : 69)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4X1	Gene names	UGT2A1
Domain Architecture
Description	UDP-glucuronosyltransferase 2A1 precursor (EC 2.4.1.17).

MUG1_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.014572 (rank : 64)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

MUG2_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.014962 (rank : 63)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

CDKL3_MOUSE
θ value	8.99809 (rank : 39)	NC score	-0.001513 (rank : 70)
Query Neighborhood Hits	44	Target Neighborhood Hits	857	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).

EWS_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.016685 (rank : 60)
Query Neighborhood Hits	44	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.016256 (rank : 62)
Query Neighborhood Hits	44	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

GASP1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.009352 (rank : 67)
Query Neighborhood Hits	44	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JY77, O43168, Q96LA1	Gene names	GPRASP1, GASP, KIAA0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

TCF20_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.016282 (rank : 61)
Query Neighborhood Hits	44	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.017676 (rank : 59)
Query Neighborhood Hits	44	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

NKTR_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.052137 (rank : 54)
Query Neighborhood Hits	44	Target Neighborhood Hits	658	Shared Neighborhood Hits	8
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

PPIA_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.066256 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

PPIA_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.066306 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIB_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.058811 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P23284, Q9BVK5	Gene names	PPIB, CYPB
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIB_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.058735 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P24369	Gene names	Ppib
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIC_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.058701 (rank : 47)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P45877	Gene names	PPIC, CYPC
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPIC_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.058329 (rank : 48)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P30412	Gene names	Ppic, Cypc
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPID_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.052684 (rank : 51)
Query Neighborhood Hits	44	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

PPID_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.053068 (rank : 50)
Query Neighborhood Hits	44	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR16, Q543G1	Gene names	Ppid
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40).

PPIE_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.052593 (rank : 53)
Query Neighborhood Hits	44	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNP9, O43634, O43635, Q5TGA0, Q9UIZ5	Gene names	PPIE, CYP33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

PPIE_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.052639 (rank : 52)
Query Neighborhood Hits	44	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZH3, Q9D8C0	Gene names	Ppie, Cyp33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

PPIF_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.065896 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P30405, Q5W131	Gene names	PPIF, CYP3
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIF_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.066958 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KR7	Gene names	Ppif
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIH_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.059106 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O43447	Gene names	PPIH, CYP20, CYPH
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH).

PPIH_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.059617 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D868, Q9CQU7	Gene names	Ppih
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H).

RANG_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.110245 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

RANG_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.111029 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RBP22_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.118589 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RBP26_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.118302 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

RGPD8_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.118380 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

VCIP1_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.111951 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.112080 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ZFAN5_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.065882 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O76080	Gene names	ZFAND5, ZA20D2, ZNF216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN5_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.065233 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN6_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.067501 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

ZFAN6_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.062136 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

Hits sorted by NC score

ZRAN1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

TNAP3_MOUSE
NC score	0.707938 (rank : 2)	θ value	4.89182e-30 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

TNAP3_HUMAN
NC score	0.701019 (rank : 3)	θ value	8.3442e-30 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

OTU7A_HUMAN
NC score	0.684976 (rank : 4)	θ value	1.24688e-25 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7A_MOUSE
NC score	0.680726 (rank : 5)	θ value	1.62847e-25 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7B_HUMAN
NC score	0.679850 (rank : 6)	θ value	3.87602e-27 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	132	Shared Neighborhood Hits	6
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

NU153_HUMAN
NC score	0.319819 (rank : 7)	θ value	3.64472e-09 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

RNF31_HUMAN
NC score	0.231959 (rank : 8)	θ value	1.43324e-05 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q96EP0, Q86VI2, Q8TEI0, Q96GB4, Q96NF1, Q9H5F1, Q9NWD2	Gene names	RNF31, ZIBRA
Domain Architecture
Description	RING finger protein 31 (Zinc in-between-RING-finger ubiquitin- associated domain protein).

RNF31_MOUSE
NC score	0.227783 (rank : 9)	θ value	1.87187e-05 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q924T7	Gene names	Rnf31
Domain Architecture
Description	RING finger protein 31.

RBP2_MOUSE
NC score	0.196760 (rank : 10)	θ value	6.00763e-12 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	232	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

YAF2_MOUSE
NC score	0.195626 (rank : 11)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	17	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LW6, Q3UFD4, Q9DBE4	Gene names	Yaf2
Domain Architecture
Description	YY1-associated factor 2.

RBP2_HUMAN
NC score	0.191855 (rank : 12)	θ value	1.25267e-09 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	249	Shared Neighborhood Hits	16
SwissProt Accessions	P49792, Q13074, Q15280, Q53TE2, Q59FH7	Gene names	RANBP2, NUP358
Domain Architecture
Description	Ran-binding protein 2 (RanBP2) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (358 kDa nucleoporin) (P270).

YAF2_HUMAN
NC score	0.190989 (rank : 13)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY57, Q99710	Gene names	YAF2
Domain Architecture
Description	YY1-associated factor 2.

RYBP_HUMAN
NC score	0.176625 (rank : 14)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	50	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

RYBP_MOUSE
NC score	0.173368 (rank : 15)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

NEIL3_MOUSE
NC score	0.150177 (rank : 16)	θ value	0.00869519 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K203, Q8CD85, Q8R3P4	Gene names	Neil3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

NEIL3_HUMAN
NC score	0.149190 (rank : 17)	θ value	0.0148317 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAT5, Q2PPJ3, Q8NG51, Q9NV95	Gene names	NEIL3
Domain Architecture	No domain graphic available
Description	Endonuclease VIII-like 3 (Nei-like 3) (DNA glycosylase FPG2).

TAB2_HUMAN
NC score	0.136584 (rank : 18)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TAB2_MOUSE
NC score	0.131888 (rank : 19)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	245	Shared Neighborhood Hits	17
SwissProt Accessions	Q99K90, Q3UGP1, Q8BTP4, Q8CHD3, Q99KP4	Gene names	Map3k7ip2, Kiaa0733, Tab2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2) (TAB2).

RBP22_HUMAN
NC score	0.118589 (rank : 20)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q53T03, Q53QN2, Q59GM7	Gene names	RANBP2L2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 2 (RanBP2L2).

RGPD8_HUMAN
NC score	0.118380 (rank : 21)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	44	Target Neighborhood Hits	135	Shared Neighborhood Hits	3
SwissProt Accessions	Q99666	Gene names	RGPD8, RANBP2L1
Domain Architecture	No domain graphic available
Description	RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 1) (RanBP2L1) (Sperm membrane protein BS-63).

RBP26_HUMAN
NC score	0.118302 (rank : 22)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	44	Target Neighborhood Hits	146	Shared Neighborhood Hits	3
SwissProt Accessions	Q68DN6, Q6V1X0	Gene names	RANBP2L6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 6 (RanBP2L6).

TAB3_HUMAN
NC score	0.118010 (rank : 23)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	168	Shared Neighborhood Hits	13
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TAB3_MOUSE
NC score	0.114005 (rank : 24)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	273	Shared Neighborhood Hits	15
SwissProt Accessions	Q571K4	Gene names	Map3k7ip3, Kiaa4135, Tab3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3).

ZRAB2_HUMAN
NC score	0.112546 (rank : 25)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	O95218, Q9UP63	Gene names	ZRANB2, ZIS, ZNF265
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 2 Zinc finger protein 265 (Zinc finger, splicing).

VCIP1_MOUSE
NC score	0.112080 (rank : 26)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_HUMAN
NC score	0.111951 (rank : 27)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

RANG_MOUSE
NC score	0.111029 (rank : 28)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	P34022, P34023, Q3TL81, Q9D894, Q9DCA3	Gene names	Ranbp1, Htf9-a, Htf9a
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RANBP1) (HpaII tiny fragments locus 9a protein).

RANG_HUMAN
NC score	0.110245 (rank : 29)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	44	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P43487	Gene names	RANBP1
Domain Architecture
Description	Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1).

NPL4_MOUSE
NC score	0.084139 (rank : 30)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	P60670	Gene names	Nploc4, Kiaa1499, Npl4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

NPL4_HUMAN
NC score	0.084066 (rank : 31)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q8TAT6, Q8N3J1, Q9H8V2, Q9H964, Q9NWR5, Q9P229	Gene names	NPLOC4, KIAA1499, NPL4
Domain Architecture
Description	Nuclear protein localization protein 4 homolog (Protein NPL4).

R113B_HUMAN
NC score	0.068405 (rank : 32)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IZP6, Q8WWF9, Q96QY9	Gene names	RNF113B, RNF161, ZNF183L1
Domain Architecture
Description	RING finger protein 113B (Zinc finger protein 183-like 1).

ZFAN6_HUMAN
NC score	0.067501 (rank : 33)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

PPIF_MOUSE
NC score	0.066958 (rank : 34)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KR7	Gene names	Ppif
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

PPIA_MOUSE
NC score	0.066306 (rank : 35)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P17742, Q9CWJ5, Q9R137	Gene names	Ppia
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein) (SP18).

PPIA_HUMAN
NC score	0.066256 (rank : 36)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P62937, P05092, Q6IBU5, Q96IX3, Q9BRU4, Q9BTY9, Q9UC61	Gene names	PPIA, CYPA
Domain Architecture	No domain graphic available
Description	Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) (Cyclosporin A-binding protein).

PPIF_HUMAN
NC score	0.065896 (rank : 37)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P30405, Q5W131	Gene names	PPIF, CYP3
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase, mitochondrial precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin F).

ZFAN5_HUMAN
NC score	0.065882 (rank : 38)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O76080	Gene names	ZFAND5, ZA20D2, ZNF216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN5_MOUSE
NC score	0.065233 (rank : 39)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

SPN90_MOUSE
NC score	0.062974 (rank : 40)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ESJ4, Q68G72	Gene names	Nckipsd, Spin90, Wasbp
Domain Architecture	No domain graphic available
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (N-WASP-interacting protein, 90kDa) (Wiskott-Aldrich syndrome protein-binding protein WISH) (N-WASP-binding protein).

ZFAN6_MOUSE
NC score	0.062136 (rank : 41)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	44	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

R113A_HUMAN
NC score	0.060321 (rank : 42)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	177	Shared Neighborhood Hits	3
SwissProt Accessions	O15541	Gene names	RNF113A, RNF113, ZNF183
Domain Architecture
Description	RING finger protein 113A (Zinc finger protein 183).

PPIH_MOUSE
NC score	0.059617 (rank : 43)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D868, Q9CQU7	Gene names	Ppih
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H).

PPIH_HUMAN
NC score	0.059106 (rank : 44)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	O43447	Gene names	PPIH, CYP20, CYPH
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase H (EC 5.2.1.8) (PPIase H) (Rotamase H) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH).

PPIB_HUMAN
NC score	0.058811 (rank : 45)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P23284, Q9BVK5	Gene names	PPIB, CYPB
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIB_MOUSE
NC score	0.058735 (rank : 46)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P24369	Gene names	Ppib
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase B precursor (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin B) (S-cyclophilin) (SCYLP) (CYP-S1).

PPIC_HUMAN
NC score	0.058701 (rank : 47)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P45877	Gene names	PPIC, CYPC
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

PPIC_MOUSE
NC score	0.058329 (rank : 48)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P30412	Gene names	Ppic, Cypc
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase C (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin C).

SPN90_HUMAN
NC score	0.057117 (rank : 49)	θ value	1.06291 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NZQ3, Q9UGM8	Gene names	NCKIPSD, AF3P21, SPIN90
Domain Architecture
Description	SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).

PPID_MOUSE
NC score	0.053068 (rank : 50)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	44	Target Neighborhood Hits	98	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CR16, Q543G1	Gene names	Ppid
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40).

PPID_HUMAN
NC score	0.052684 (rank : 51)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	44	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q08752	Gene names	PPID, CYP40, CYPD
Domain Architecture
Description	40 kDa peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) (PPIase) (Rotamase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein).

PPIE_MOUSE
NC score	0.052639 (rank : 52)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	44	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZH3, Q9D8C0	Gene names	Ppie, Cyp33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

PPIE_HUMAN
NC score	0.052593 (rank : 53)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	44	Target Neighborhood Hits	205	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNP9, O43634, O43635, Q5TGA0, Q9UIZ5	Gene names	PPIE, CYP33
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) (PPIase E) (Rotamase E) (Cyclophilin E) (Cyclophilin 33).

NKTR_HUMAN
NC score	0.052137 (rank : 54)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	658	Shared Neighborhood Hits	8
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

SRGP2_MOUSE
NC score	0.025135 (rank : 55)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	324	Shared Neighborhood Hits	5
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP2_HUMAN
NC score	0.024854 (rank : 56)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	331	Shared Neighborhood Hits	5
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

ELOA2_HUMAN
NC score	0.023174 (rank : 57)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

SRGP1_HUMAN
NC score	0.022083 (rank : 58)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	390	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

TCF20_MOUSE
NC score	0.017676 (rank : 59)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	396	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

EWS_HUMAN
NC score	0.016685 (rank : 60)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

TCF20_HUMAN
NC score	0.016282 (rank : 61)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	323	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

EWS_MOUSE
NC score	0.016256 (rank : 62)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	271	Shared Neighborhood Hits	4
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

MUG2_MOUSE
NC score	0.014962 (rank : 63)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	P28666	Gene names	Mug2, Mug-2
Domain Architecture
Description	Murinoglobulin-2 precursor (MuG2).

MUG1_MOUSE
NC score	0.014572 (rank : 64)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P28665	Gene names	Mug1, Mug-1
Domain Architecture
Description	Murinoglobulin-1 precursor (MuG1).

EVPL_HUMAN
NC score	0.013696 (rank : 65)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	895	Shared Neighborhood Hits	4
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MYH14_MOUSE
NC score	0.009955 (rank : 66)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	1225	Shared Neighborhood Hits	4
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

GASP1_HUMAN
NC score	0.009352 (rank : 67)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q5JY77, O43168, Q96LA1	Gene names	GPRASP1, GASP, KIAA0443
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 1 (GASP-1).

MYH14_HUMAN
NC score	0.008977 (rank : 68)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	995	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

UDA1_HUMAN
NC score	0.007267 (rank : 69)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y4X1	Gene names	UGT2A1
Domain Architecture
Description	UDP-glucuronosyltransferase 2A1 precursor (EC 2.4.1.17).

CDKL3_MOUSE
NC score	-0.001513 (rank : 70)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	857	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BLF2, Q5M6W2, Q8BKR2, Q8BL49, Q8BVE0, Q8K134	Gene names	Cdkl3
Domain Architecture	No domain graphic available
Description	Cyclin-dependent kinase-like 3 (EC 2.7.11.22).