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Network neighborhood for query Sequence : OTU7A_MOUSE

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OTU7A_MOUSE
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OTU7A_HUMAN
θ value	0 (rank : 1)	NC score	0.985021 (rank : 2)
Query Neighborhood Hits	91	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7A_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7B_HUMAN
θ value	0 (rank : 3)	NC score	0.947698 (rank : 3)
Query Neighborhood Hits	91	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

TNAP3_HUMAN
θ value	1.12253e-42 (rank : 4)	NC score	0.769134 (rank : 5)
Query Neighborhood Hits	91	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

TNAP3_MOUSE
θ value	1.46607e-42 (rank : 5)	NC score	0.772366 (rank : 4)
Query Neighborhood Hits	91	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

ZRAN1_HUMAN
θ value	1.62847e-25 (rank : 6)	NC score	0.680726 (rank : 6)
Query Neighborhood Hits	91	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

RRBP1_MOUSE
θ value	0.00228821 (rank : 7)	NC score	0.036752 (rank : 30)
Query Neighborhood Hits	91	Target Neighborhood Hits	1650	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

VCIP1_HUMAN
θ value	0.00298849 (rank : 8)	NC score	0.228252 (rank : 8)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_MOUSE
θ value	0.00298849 (rank : 9)	NC score	0.228298 (rank : 7)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ZFP28_HUMAN
θ value	0.00509761 (rank : 10)	NC score	0.004365 (rank : 88)
Query Neighborhood Hits	91	Target Neighborhood Hits	843	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

CBX2_HUMAN
θ value	0.00869519 (rank : 11)	NC score	0.054729 (rank : 19)
Query Neighborhood Hits	91	Target Neighborhood Hits	264	Shared Neighborhood Hits	9
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

NFH_MOUSE
θ value	0.0113563 (rank : 12)	NC score	0.030473 (rank : 42)
Query Neighborhood Hits	91	Target Neighborhood Hits	2247	Shared Neighborhood Hits	40
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAGE1_HUMAN
θ value	0.0252991 (rank : 13)	NC score	0.029101 (rank : 43)
Query Neighborhood Hits	91	Target Neighborhood Hits	1389	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

GRIN1_HUMAN
θ value	0.0563607 (rank : 14)	NC score	0.046759 (rank : 24)
Query Neighborhood Hits	91	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

OGFR_HUMAN
θ value	0.0736092 (rank : 15)	NC score	0.035998 (rank : 32)
Query Neighborhood Hits	91	Target Neighborhood Hits	1582	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CSKI1_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.023546 (rank : 53)
Query Neighborhood Hits	91	Target Neighborhood Hits	997	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

KCD18_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.052664 (rank : 21)
Query Neighborhood Hits	91	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

PCOC1_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.021142 (rank : 59)
Query Neighborhood Hits	91	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

ZFAN5_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.168415 (rank : 9)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	O76080	Gene names	ZFAND5, ZA20D2, ZNF216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN5_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.167740 (rank : 10)
Query Neighborhood Hits	91	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

LAMA2_HUMAN
θ value	0.279714 (rank : 21)	NC score	0.017651 (rank : 66)
Query Neighborhood Hits	91	Target Neighborhood Hits	1092	Shared Neighborhood Hits	13
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

IQGA1_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.033269 (rank : 35)
Query Neighborhood Hits	91	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

NSF1C_HUMAN
θ value	0.365318 (rank : 23)	NC score	0.088995 (rank : 15)
Query Neighborhood Hits	91	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

ZFAN6_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.166317 (rank : 11)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

ZFAN6_MOUSE
θ value	0.365318 (rank : 25)	NC score	0.157911 (rank : 12)
Query Neighborhood Hits	91	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

JPH2_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.035351 (rank : 33)
Query Neighborhood Hits	91	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

MUC1_HUMAN
θ value	0.47712 (rank : 27)	NC score	0.028861 (rank : 44)
Query Neighborhood Hits	91	Target Neighborhood Hits	975	Shared Neighborhood Hits	17
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RABX5_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.091143 (rank : 14)
Query Neighborhood Hits	91	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RABX5_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.100464 (rank : 13)
Query Neighborhood Hits	91	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

RIMB1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.030618 (rank : 41)
Query Neighborhood Hits	91	Target Neighborhood Hits	1479	Shared Neighborhood Hits	23
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

ZF106_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.035154 (rank : 34)
Query Neighborhood Hits	91	Target Neighborhood Hits	470	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

DMXL1_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.025895 (rank : 49)
Query Neighborhood Hits	91	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

GASP2_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.023966 (rank : 51)
Query Neighborhood Hits	91	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

PAK4_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.003224 (rank : 89)
Query Neighborhood Hits	91	Target Neighborhood Hits	1098	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

PITM1_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.037652 (rank : 27)
Query Neighborhood Hits	91	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

USBP1_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.031410 (rank : 40)
Query Neighborhood Hits	91	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

HDAC6_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.017566 (rank : 67)
Query Neighborhood Hits	91	Target Neighborhood Hits	145	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

IRS1_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.022345 (rank : 55)
Query Neighborhood Hits	91	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

PITM1_HUMAN
θ value	1.38821 (rank : 39)	NC score	0.025019 (rank : 50)
Query Neighborhood Hits	91	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

CLSPN_MOUSE
θ value	1.81305 (rank : 40)	NC score	0.037158 (rank : 28)
Query Neighborhood Hits	91	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

PRRT3_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.033172 (rank : 36)
Query Neighborhood Hits	91	Target Neighborhood Hits	998	Shared Neighborhood Hits	22
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TGON2_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.036074 (rank : 31)
Query Neighborhood Hits	91	Target Neighborhood Hits	1037	Shared Neighborhood Hits	32
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

FAF1_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.058633 (rank : 17)
Query Neighborhood Hits	91	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

FAF1_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.053157 (rank : 20)
Query Neighborhood Hits	91	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

FUBP3_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.015726 (rank : 69)
Query Neighborhood Hits	91	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

GRIPE_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.031489 (rank : 39)
Query Neighborhood Hits	91	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

JUNB_MOUSE
θ value	2.36792 (rank : 47)	NC score	0.028245 (rank : 45)
Query Neighborhood Hits	91	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

MBB1A_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.028016 (rank : 46)
Query Neighborhood Hits	91	Target Neighborhood Hits	665	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

NKTR_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.018521 (rank : 65)
Query Neighborhood Hits	91	Target Neighborhood Hits	658	Shared Neighborhood Hits	14
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NSF1C_MOUSE
θ value	2.36792 (rank : 50)	NC score	0.064850 (rank : 16)
Query Neighborhood Hits	91	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

ANKY1_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.019452 (rank : 62)
Query Neighborhood Hits	91	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

BRWD1_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.012199 (rank : 71)
Query Neighborhood Hits	91	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

GA2L2_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.023644 (rank : 52)
Query Neighborhood Hits	91	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

NIPBL_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.019231 (rank : 63)
Query Neighborhood Hits	91	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SCG2_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.027096 (rank : 48)
Query Neighborhood Hits	91	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

DMXL1_MOUSE
θ value	4.03905 (rank : 56)	NC score	0.021702 (rank : 58)
Query Neighborhood Hits	91	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

MYH7_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.008984 (rank : 79)
Query Neighborhood Hits	91	Target Neighborhood Hits	1559	Shared Neighborhood Hits	14
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

PKDRE_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.014683 (rank : 70)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

RBBP6_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.019951 (rank : 61)
Query Neighborhood Hits	91	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RHBT2_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.011776 (rank : 75)
Query Neighborhood Hits	91	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYZ6, O94825, Q8N4A8, Q9BZK6	Gene names	RHOBTB2, DBC2, KIAA0717
Domain Architecture
Description	Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83).

RHBT2_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.011882 (rank : 73)
Query Neighborhood Hits	91	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V93, Q8K1A8	Gene names	Rhobtb2, Dbc2
Domain Architecture
Description	Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein homolog).

TR150_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.032016 (rank : 38)
Query Neighborhood Hits	91	Target Neighborhood Hits	313	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TRPV4_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.009698 (rank : 77)
Query Neighborhood Hits	91	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

ZF106_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.028016 (rank : 47)
Query Neighborhood Hits	91	Target Neighborhood Hits	472	Shared Neighborhood Hits	11
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CK024_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.032292 (rank : 37)
Query Neighborhood Hits	91	Target Neighborhood Hits	408	Shared Neighborhood Hits	14
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CN115_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.057412 (rank : 18)
Query Neighborhood Hits	91	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8Y1, Q9NVC7	Gene names	C14orf115
Domain Architecture
Description	Uncharacterized protein C14orf115.

EHMT1_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.005843 (rank : 85)
Query Neighborhood Hits	91	Target Neighborhood Hits	417	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

HOME2_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.011863 (rank : 74)
Query Neighborhood Hits	91	Target Neighborhood Hits	882	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

JUNB_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.020083 (rank : 60)
Query Neighborhood Hits	91	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

MARK2_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.000828 (rank : 91)
Query Neighborhood Hits	91	Target Neighborhood Hits	1056	Shared Neighborhood Hits	11
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

MYH6_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.008481 (rank : 80)
Query Neighborhood Hits	91	Target Neighborhood Hits	1426	Shared Neighborhood Hits	13
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	5.27518 (rank : 72)	NC score	0.008454 (rank : 81)
Query Neighborhood Hits	91	Target Neighborhood Hits	1501	Shared Neighborhood Hits	12
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RAB23_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.005018 (rank : 86)
Query Neighborhood Hits	91	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	P35288	Gene names	Rab23
Domain Architecture
Description	Ras-related protein Rab-23 (Rab-15).

ULK1_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.000745 (rank : 93)
Query Neighborhood Hits	91	Target Neighborhood Hits	1121	Shared Neighborhood Hits	12
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

CORIN_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.001350 (rank : 90)
Query Neighborhood Hits	91	Target Neighborhood Hits	451	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ES8L1_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.008432 (rank : 82)
Query Neighborhood Hits	91	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

K0317_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.009603 (rank : 78)
Query Neighborhood Hits	91	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

LAMB3_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.007543 (rank : 83)
Query Neighborhood Hits	91	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

MYO15_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.010455 (rank : 76)
Query Neighborhood Hits	91	Target Neighborhood Hits	467	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

RUSC2_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.017446 (rank : 68)
Query Neighborhood Hits	91	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SF3B1_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.039243 (rank : 25)
Query Neighborhood Hits	91	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.039196 (rank : 26)
Query Neighborhood Hits	91	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SUHW4_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.004442 (rank : 87)
Query Neighborhood Hits	91	Target Neighborhood Hits	860	Shared Neighborhood Hits	8
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ZKSC1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.000826 (rank : 92)
Query Neighborhood Hits	91	Target Neighborhood Hits	949	Shared Neighborhood Hits	10
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

BSN_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.036940 (rank : 29)
Query Neighborhood Hits	91	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ELOA2_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.021878 (rank : 57)
Query Neighborhood Hits	91	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

GRIPE_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.022870 (rank : 54)
Query Neighborhood Hits	91	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

K2027_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.022231 (rank : 56)
Query Neighborhood Hits	91	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MDC1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.018888 (rank : 64)
Query Neighborhood Hits	91	Target Neighborhood Hits	1446	Shared Neighborhood Hits	29
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PGCB_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.007477 (rank : 84)
Query Neighborhood Hits	91	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

T22D4_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.012137 (rank : 72)
Query Neighborhood Hits	91	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

PRB3_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.050291 (rank : 23)
Query Neighborhood Hits	91	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

PRP1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.052313 (rank : 22)
Query Neighborhood Hits	91	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

Hits sorted by NC score

OTU7A_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	91
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7A_HUMAN
NC score	0.985021 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	91	Target Neighborhood Hits	74	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7B_HUMAN
NC score	0.947698 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	91	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

TNAP3_MOUSE
NC score	0.772366 (rank : 4)	θ value	1.46607e-42 (rank : 5)
Query Neighborhood Hits	91	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

TNAP3_HUMAN
NC score	0.769134 (rank : 5)	θ value	1.12253e-42 (rank : 4)
Query Neighborhood Hits	91	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

ZRAN1_HUMAN
NC score	0.680726 (rank : 6)	θ value	1.62847e-25 (rank : 6)
Query Neighborhood Hits	91	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

VCIP1_MOUSE
NC score	0.228298 (rank : 7)	θ value	0.00298849 (rank : 9)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_HUMAN
NC score	0.228252 (rank : 8)	θ value	0.00298849 (rank : 8)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	8
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ZFAN5_HUMAN
NC score	0.168415 (rank : 9)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	O76080	Gene names	ZFAND5, ZA20D2, ZNF216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN5_MOUSE
NC score	0.167740 (rank : 10)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	91	Target Neighborhood Hits	30	Shared Neighborhood Hits	12
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN6_HUMAN
NC score	0.166317 (rank : 11)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	91	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

ZFAN6_MOUSE
NC score	0.157911 (rank : 12)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	91	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

RABX5_MOUSE
NC score	0.100464 (rank : 13)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	91	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

RABX5_HUMAN
NC score	0.091143 (rank : 14)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	91	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

NSF1C_HUMAN
NC score	0.088995 (rank : 15)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	91	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

NSF1C_MOUSE
NC score	0.064850 (rank : 16)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	91	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

FAF1_HUMAN
NC score	0.058633 (rank : 17)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	91	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

CN115_HUMAN
NC score	0.057412 (rank : 18)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	91	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8Y1, Q9NVC7	Gene names	C14orf115
Domain Architecture
Description	Uncharacterized protein C14orf115.

CBX2_HUMAN
NC score	0.054729 (rank : 19)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	91	Target Neighborhood Hits	264	Shared Neighborhood Hits	9
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

FAF1_MOUSE
NC score	0.053157 (rank : 20)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	91	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

KCD18_HUMAN
NC score	0.052664 (rank : 21)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	91	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

PRP1_HUMAN
NC score	0.052313 (rank : 22)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	91	Target Neighborhood Hits	385	Shared Neighborhood Hits	20
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRB3_HUMAN
NC score	0.050291 (rank : 23)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	91	Target Neighborhood Hits	318	Shared Neighborhood Hits	19
SwissProt Accessions	Q04118, Q15188, Q7M4M9	Gene names	PRB3
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 3 precursor (Parotid salivary glycoprotein G1) (Proline-rich protein G1).

GRIN1_HUMAN
NC score	0.046759 (rank : 24)	θ value	0.0563607 (rank : 14)
Query Neighborhood Hits	91	Target Neighborhood Hits	681	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SF3B1_HUMAN
NC score	0.039243 (rank : 25)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	91	Target Neighborhood Hits	341	Shared Neighborhood Hits	13
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

SF3B1_MOUSE
NC score	0.039196 (rank : 26)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	91	Target Neighborhood Hits	352	Shared Neighborhood Hits	13
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PITM1_MOUSE
NC score	0.037652 (rank : 27)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	91	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

CLSPN_MOUSE
NC score	0.037158 (rank : 28)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	91	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

BSN_MOUSE
NC score	0.036940 (rank : 29)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	91	Target Neighborhood Hits	2057	Shared Neighborhood Hits	39
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

RRBP1_MOUSE
NC score	0.036752 (rank : 30)	θ value	0.00228821 (rank : 7)
Query Neighborhood Hits	91	Target Neighborhood Hits	1650	Shared Neighborhood Hits	26
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TGON2_HUMAN
NC score	0.036074 (rank : 31)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	91	Target Neighborhood Hits	1037	Shared Neighborhood Hits	32
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

OGFR_HUMAN
NC score	0.035998 (rank : 32)	θ value	0.0736092 (rank : 15)
Query Neighborhood Hits	91	Target Neighborhood Hits	1582	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

JPH2_HUMAN
NC score	0.035351 (rank : 33)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	91	Target Neighborhood Hits	639	Shared Neighborhood Hits	21
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

ZF106_HUMAN
NC score	0.035154 (rank : 34)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	91	Target Neighborhood Hits	470	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

IQGA1_HUMAN
NC score	0.033269 (rank : 35)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	91	Target Neighborhood Hits	250	Shared Neighborhood Hits	10
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

PRRT3_HUMAN
NC score	0.033172 (rank : 36)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	91	Target Neighborhood Hits	998	Shared Neighborhood Hits	22
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CK024_HUMAN
NC score	0.032292 (rank : 37)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	91	Target Neighborhood Hits	408	Shared Neighborhood Hits	14
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

TR150_HUMAN
NC score	0.032016 (rank : 38)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	91	Target Neighborhood Hits	313	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

GRIPE_HUMAN
NC score	0.031489 (rank : 39)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	91	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

USBP1_HUMAN
NC score	0.031410 (rank : 40)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	91	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N6Y0, Q8NBX7, Q96KH3, Q9BYI8	Gene names	USHBP1, AIEBP, MCC2
Domain Architecture	No domain graphic available
Description	USH1C-binding protein 1 (Usher syndrome type-1C protein-binding protein 1) (MCC-2) (AIE-75 binding protein).

RIMB1_HUMAN
NC score	0.030618 (rank : 41)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	91	Target Neighborhood Hits	1479	Shared Neighborhood Hits	23
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NFH_MOUSE
NC score	0.030473 (rank : 42)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	91	Target Neighborhood Hits	2247	Shared Neighborhood Hits	40
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAGE1_HUMAN
NC score	0.029101 (rank : 43)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	91	Target Neighborhood Hits	1389	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC1_HUMAN
NC score	0.028861 (rank : 44)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	91	Target Neighborhood Hits	975	Shared Neighborhood Hits	17
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

JUNB_MOUSE
NC score	0.028245 (rank : 45)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	91	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

MBB1A_HUMAN
NC score	0.028016 (rank : 46)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	91	Target Neighborhood Hits	665	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

ZF106_MOUSE
NC score	0.028016 (rank : 47)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	91	Target Neighborhood Hits	472	Shared Neighborhood Hits	11
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

SCG2_HUMAN
NC score	0.027096 (rank : 48)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	91	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

DMXL1_HUMAN
NC score	0.025895 (rank : 49)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	91	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

PITM1_HUMAN
NC score	0.025019 (rank : 50)	θ value	1.38821 (rank : 39)
Query Neighborhood Hits	91	Target Neighborhood Hits	129	Shared Neighborhood Hits	6
SwissProt Accessions	O00562, Q6T7X3, Q8TBN3, Q9BZ73	Gene names	PITPNM1, DRES9, NIR2, PITPNM
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog).

GASP2_HUMAN
NC score	0.023966 (rank : 51)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	91	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q96D09, Q8NAB4	Gene names	GPRASP2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

GA2L2_HUMAN
NC score	0.023644 (rank : 52)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	91	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

CSKI1_HUMAN
NC score	0.023546 (rank : 53)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	91	Target Neighborhood Hits	997	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

GRIPE_MOUSE
NC score	0.022870 (rank : 54)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	91	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

IRS1_HUMAN
NC score	0.022345 (rank : 55)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	91	Target Neighborhood Hits	109	Shared Neighborhood Hits	4
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

K2027_HUMAN
NC score	0.022231 (rank : 56)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	91	Target Neighborhood Hits	194	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

ELOA2_HUMAN
NC score	0.021878 (rank : 57)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	91	Target Neighborhood Hits	165	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

DMXL1_MOUSE
NC score	0.021702 (rank : 58)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	91	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PNC0, Q3TLG8, Q6PHM6, Q8BQF2	Gene names	Dmxl1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

PCOC1_HUMAN
NC score	0.021142 (rank : 59)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	91	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

JUNB_HUMAN
NC score	0.020083 (rank : 60)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	91	Target Neighborhood Hits	97	Shared Neighborhood Hits	5
SwissProt Accessions	P17275, Q96GH3	Gene names	JUNB
Domain Architecture
Description	Transcription factor jun-B.

RBBP6_HUMAN
NC score	0.019951 (rank : 61)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	91	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

ANKY1_HUMAN
NC score	0.019452 (rank : 62)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	91	Target Neighborhood Hits	248	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

NIPBL_HUMAN
NC score	0.019231 (rank : 63)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	91	Target Neighborhood Hits	1311	Shared Neighborhood Hits	23
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

MDC1_HUMAN
NC score	0.018888 (rank : 64)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	91	Target Neighborhood Hits	1446	Shared Neighborhood Hits	29
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NKTR_HUMAN
NC score	0.018521 (rank : 65)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	91	Target Neighborhood Hits	658	Shared Neighborhood Hits	14
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

LAMA2_HUMAN
NC score	0.017651 (rank : 66)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	91	Target Neighborhood Hits	1092	Shared Neighborhood Hits	13
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

HDAC6_HUMAN
NC score	0.017566 (rank : 67)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	91	Target Neighborhood Hits	145	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

RUSC2_HUMAN
NC score	0.017446 (rank : 68)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	91	Target Neighborhood Hits	205	Shared Neighborhood Hits	12
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

FUBP3_HUMAN
NC score	0.015726 (rank : 69)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	91	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q96I24, Q92946, Q9BVB6	Gene names	FUBP3
Domain Architecture
Description	Far upstream element-binding protein 3 (FUSE-binding protein 3).

PKDRE_MOUSE
NC score	0.014683 (rank : 70)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	91	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

BRWD1_HUMAN
NC score	0.012199 (rank : 71)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	91	Target Neighborhood Hits	448	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

T22D4_HUMAN
NC score	0.012137 (rank : 72)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	91	Target Neighborhood Hits	403	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y3Q8	Gene names	TSC22D4, TILZ2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2) (Tsc-22-like protein THG-1).

RHBT2_MOUSE
NC score	0.011882 (rank : 73)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	91	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q91V93, Q8K1A8	Gene names	Rhobtb2, Dbc2
Domain Architecture
Description	Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein homolog).

HOME2_MOUSE
NC score	0.011863 (rank : 74)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	91	Target Neighborhood Hits	882	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QWW1, O89025, Q9Z0E4	Gene names	Homer2, Vesl2
Domain Architecture
Description	Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up- regulated during seizure and LTP 2) (Vesl-2).

RHBT2_HUMAN
NC score	0.011776 (rank : 75)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	91	Target Neighborhood Hits	245	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BYZ6, O94825, Q8N4A8, Q9BZK6	Gene names	RHOBTB2, DBC2, KIAA0717
Domain Architecture
Description	Rho-related BTB domain-containing protein 2 (Deleted in breast cancer 2 gene protein) (p83).

MYO15_MOUSE
NC score	0.010455 (rank : 76)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	91	Target Neighborhood Hits	467	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

TRPV4_HUMAN
NC score	0.009698 (rank : 77)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	91	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

K0317_HUMAN
NC score	0.009603 (rank : 78)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	91	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

MYH7_HUMAN
NC score	0.008984 (rank : 79)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	91	Target Neighborhood Hits	1559	Shared Neighborhood Hits	14
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH6_HUMAN
NC score	0.008481 (rank : 80)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	91	Target Neighborhood Hits	1426	Shared Neighborhood Hits	13
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
NC score	0.008454 (rank : 81)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	91	Target Neighborhood Hits	1501	Shared Neighborhood Hits	12
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

ES8L1_HUMAN
NC score	0.008432 (rank : 82)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	91	Target Neighborhood Hits	162	Shared Neighborhood Hits	5
SwissProt Accessions	Q8TE68, Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0	Gene names	EPS8L1, DRC3, EPS8R1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

LAMB3_MOUSE
NC score	0.007543 (rank : 83)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	91	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

PGCB_HUMAN
NC score	0.007477 (rank : 84)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	91	Target Neighborhood Hits	478	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

EHMT1_HUMAN
NC score	0.005843 (rank : 85)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	91	Target Neighborhood Hits	417	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

RAB23_MOUSE
NC score	0.005018 (rank : 86)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	91	Target Neighborhood Hits	274	Shared Neighborhood Hits	5
SwissProt Accessions	P35288	Gene names	Rab23
Domain Architecture
Description	Ras-related protein Rab-23 (Rab-15).

SUHW4_HUMAN
NC score	0.004442 (rank : 87)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	91	Target Neighborhood Hits	860	Shared Neighborhood Hits	8
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

ZFP28_HUMAN
NC score	0.004365 (rank : 88)	θ value	0.00509761 (rank : 10)
Query Neighborhood Hits	91	Target Neighborhood Hits	843	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

PAK4_MOUSE
NC score	0.003224 (rank : 89)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	91	Target Neighborhood Hits	1098	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BTW9, Q6ZPX0, Q80Z97, Q9CS71	Gene names	Pak4, Kiaa1142
Domain Architecture
Description	Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4).

CORIN_MOUSE
NC score	0.001350 (rank : 90)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	91	Target Neighborhood Hits	451	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

MARK2_HUMAN
NC score	0.000828 (rank : 91)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	91	Target Neighborhood Hits	1056	Shared Neighborhood Hits	11
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

ZKSC1_HUMAN
NC score	0.000826 (rank : 92)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	91	Target Neighborhood Hits	949	Shared Neighborhood Hits	10
SwissProt Accessions	P17029, P52745, Q8TBW5, Q8TEK7	Gene names	ZKSCAN1, KOX18, ZNF139, ZNF36
Domain Architecture	No domain graphic available
Description	Zinc finger with KRAB and SCAN domain-containing protein 1 (Zinc finger protein 36) (Zinc finger protein KOX18).

ULK1_HUMAN
NC score	0.000745 (rank : 93)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	91	Target Neighborhood Hits	1121	Shared Neighborhood Hits	12
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).