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Network neighborhood for query Sequence : OTU7A_HUMAN

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OTU7A_HUMAN
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OTU7A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7A_MOUSE
θ value	0 (rank : 2)	NC score	0.985021 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7B_HUMAN
θ value	0 (rank : 3)	NC score	0.953395 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	20
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

TNAP3_HUMAN
θ value	1.12253e-42 (rank : 4)	NC score	0.774302 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

TNAP3_MOUSE
θ value	1.46607e-42 (rank : 5)	NC score	0.777329 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

ZRAN1_HUMAN
θ value	1.24688e-25 (rank : 6)	NC score	0.684976 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

VCIP1_HUMAN
θ value	0.00175202 (rank : 7)	NC score	0.232879 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_MOUSE
θ value	0.00175202 (rank : 8)	NC score	0.233120 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

MUC1_HUMAN
θ value	0.0148317 (rank : 9)	NC score	0.028176 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RRBP1_MOUSE
θ value	0.0330416 (rank : 10)	NC score	0.030128 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

ZFAN6_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.173647 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

ZFAN6_MOUSE
θ value	0.0961366 (rank : 12)	NC score	0.164358 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

PAK6_HUMAN
θ value	0.125558 (rank : 13)	NC score	0.005218 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	915	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PITM1_MOUSE
θ value	0.125558 (rank : 14)	NC score	0.034586 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

RIMB1_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.031472 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	1479	Shared Neighborhood Hits	14
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BSN_MOUSE
θ value	0.163984 (rank : 16)	NC score	0.042191 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	2057	Shared Neighborhood Hits	33
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

ZFAN5_HUMAN
θ value	0.163984 (rank : 17)	NC score	0.174562 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	O76080	Gene names	ZFAND5, ZA20D2, ZNF216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN5_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.173945 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

GASP2_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.029070 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

NFH_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.023146 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	2247	Shared Neighborhood Hits	30
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

NSF1C_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.089530 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

CSKI1_MOUSE
θ value	0.62314 (rank : 22)	NC score	0.014191 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	1031	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PRRT3_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.035484 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ZF106_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.035003 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	470	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

CLSPN_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.038998 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

JPH2_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.029395 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	639	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

RP3A_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.015926 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	510	Shared Neighborhood Hits	14
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MYLK_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.003637 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	1489	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

IQEC3_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.016010 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQGA1_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.026897 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

LAMA2_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.012854 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	1092	Shared Neighborhood Hits	7
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

MEFV_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.008656 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

PDZD2_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.018176 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RABX5_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.086912 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RABX5_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.095948 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

SODE_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.027758 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O09164	Gene names	Sod3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

FAF1_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.059012 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

FAF1_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.053513 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

GRIPE_HUMAN
θ value	2.36792 (rank : 39)	NC score	0.031722 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

NSF1C_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.065240 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

ELOA2_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.025953 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

FAIM2_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.018090 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWQ8, Q9UJY9, Q9Y2F7	Gene names	FAIM2, KIAA0950, LFG, TMBIM2
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2).

JHD3B_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.010393 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

MEF2B_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.015332 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

TGON2_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.027322 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	1037	Shared Neighborhood Hits	27
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

CAC1A_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.008615 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

CDC20_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.008183 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

CL026_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.019467 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NXH8, Q3UMX5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf26 homolog.

KCD18_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.039662 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

PHLPP_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.009570 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	604	Shared Neighborhood Hits	12
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SPEG_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.005269 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	1762	Shared Neighborhood Hits	19
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TR150_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.029480 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ZF106_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.027417 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	472	Shared Neighborhood Hits	12
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

CN115_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.057750 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8Y1, Q9NVC7	Gene names	C14orf115
Domain Architecture
Description	Uncharacterized protein C14orf115.

DACT1_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.017574 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

FREM3_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.008070 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

GA2L2_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.021464 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

LTBP2_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.003516 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	617	Shared Neighborhood Hits	7
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

NKTR_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.016101 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	658	Shared Neighborhood Hits	14
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

NOS1_HUMAN
θ value	5.27518 (rank : 60)	NC score	0.008955 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

RAB23_MOUSE
θ value	5.27518 (rank : 61)	NC score	0.004501 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	P35288	Gene names	Rab23
Domain Architecture
Description	Ras-related protein Rab-23 (Rab-15).

BRWD1_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.010352 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	448	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

K0317_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.009742 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

PSIP1_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.015937 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

RFIP5_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.012807 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

SEPT9_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.008986 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	706	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ALMS1_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.009617 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	356	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

FILA_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.016739 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	685	Shared Neighborhood Hits	16
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

GRIPE_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.023046 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

JUNB_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.018384 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

P2RX2_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.008273 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

RBBP6_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.017338 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

S6A17_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.003064 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1V8, Q5T5Q9	Gene names	SLC6A17, NTT4
Domain Architecture	No domain graphic available
Description	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT4 (Solute carrier family 6 member 17).

SCG2_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.021238 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

Hits sorted by NC score

OTU7A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	74	Target Neighborhood Hits	74	Shared Neighborhood Hits	74
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7A_MOUSE
NC score	0.985021 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	74	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R554	Gene names	Otud7a, Otud7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OTU7B_HUMAN
NC score	0.953395 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	74	Target Neighborhood Hits	132	Shared Neighborhood Hits	20
SwissProt Accessions	Q6GQQ9, Q8WWA7, Q9NQ53, Q9UFF4	Gene names	OTUD7B, ZA20D1
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7B (EC 3.-.-.-) (Zinc finger protein Cezanne) (Zinc finger A20 domain-containing protein 1) (Cellular zinc finger anti-NF-kappa B protein).

TNAP3_MOUSE
NC score	0.777329 (rank : 4)	θ value	1.46607e-42 (rank : 5)
Query Neighborhood Hits	74	Target Neighborhood Hits	35	Shared Neighborhood Hits	15
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

TNAP3_HUMAN
NC score	0.774302 (rank : 5)	θ value	1.12253e-42 (rank : 4)
Query Neighborhood Hits	74	Target Neighborhood Hits	58	Shared Neighborhood Hits	16
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

ZRAN1_HUMAN
NC score	0.684976 (rank : 6)	θ value	1.24688e-25 (rank : 6)
Query Neighborhood Hits	74	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UGI0	Gene names	ZRANB1, TRABID
Domain Architecture
Description	Zinc finger Ran-binding domain-containing protein 1 (Protein TRABID).

VCIP1_MOUSE
NC score	0.233120 (rank : 7)	θ value	0.00175202 (rank : 8)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CDG3, Q7TMU9, Q8BP90	Gene names	Vcpip1, Vcip135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

VCIP1_HUMAN
NC score	0.232879 (rank : 8)	θ value	0.00175202 (rank : 7)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	Q96JH7, Q504T4, Q86T93, Q86W01, Q8N3A9, Q9H5R8	Gene names	VCPIP1, KIAA1850, VCIP135
Domain Architecture
Description	Deubiquitinating protein VCIP135 (EC 3.4.22.-) (Valosin-containing protein p97/p47 complex-interacting protein p135) (Valosin-containing protein p97/p47 complex-interacting protein 1).

ZFAN5_HUMAN
NC score	0.174562 (rank : 9)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	74	Target Neighborhood Hits	26	Shared Neighborhood Hits	11
SwissProt Accessions	O76080	Gene names	ZFAND5, ZA20D2, ZNF216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN5_MOUSE
NC score	0.173945 (rank : 10)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	74	Target Neighborhood Hits	30	Shared Neighborhood Hits	11
SwissProt Accessions	O88878	Gene names	Zfand5, Za20d2, Zfp216, Znf216
Domain Architecture
Description	AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216).

ZFAN6_HUMAN
NC score	0.173647 (rank : 11)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	74	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q6FIF0, O95792, Q9BQF7, Q9GZY3	Gene names	ZFAND6, AWP1, ZA20D3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

ZFAN6_MOUSE
NC score	0.164358 (rank : 12)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	74	Target Neighborhood Hits	92	Shared Neighborhood Hits	12
SwissProt Accessions	Q9DCH6, Q9ER79	Gene names	Zfand6, Awp1, Za20d3
Domain Architecture	No domain graphic available
Description	AN1-type zinc finger protein 6 (Zinc finger A20 domain-containing protein 3) (Associated with PRK1 protein).

RABX5_MOUSE
NC score	0.095948 (rank : 13)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	74	Target Neighborhood Hits	39	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

NSF1C_HUMAN
NC score	0.089530 (rank : 14)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	74	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNZ2, Q7Z533, Q9H102, Q9NVL9, Q9UI06	Gene names	NSFL1C
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

RABX5_HUMAN
NC score	0.086912 (rank : 15)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	74	Target Neighborhood Hits	68	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

NSF1C_MOUSE
NC score	0.065240 (rank : 16)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	74	Target Neighborhood Hits	27	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CZ44, Q80Y15, Q8BYL3	Gene names	Nsfl1c
Domain Architecture
Description	NSFL1 cofactor p47 (p97 cofactor p47).

FAF1_HUMAN
NC score	0.059012 (rank : 17)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	74	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UNN5, Q9UF34, Q9UNT3, Q9Y2Z3	Gene names	FAF1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1) (hFAF1).

CN115_HUMAN
NC score	0.057750 (rank : 18)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	74	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8Y1, Q9NVC7	Gene names	C14orf115
Domain Architecture
Description	Uncharacterized protein C14orf115.

FAF1_MOUSE
NC score	0.053513 (rank : 19)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	74	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	P54731	Gene names	Faf1
Domain Architecture
Description	FAS-associated factor 1 (Protein FAF1).

BSN_MOUSE
NC score	0.042191 (rank : 20)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	74	Target Neighborhood Hits	2057	Shared Neighborhood Hits	33
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KCD18_HUMAN
NC score	0.039662 (rank : 21)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	74	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PI47, Q53T21, Q6NW26, Q6PCD8, Q8N9B7, Q96N73	Gene names	KCTD18
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein KCTD18.

CLSPN_MOUSE
NC score	0.038998 (rank : 22)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	74	Target Neighborhood Hits	292	Shared Neighborhood Hits	7
SwissProt Accessions	Q80YR7, Q69GM2	Gene names	Clspn
Domain Architecture	No domain graphic available
Description	Claspin.

PRRT3_MOUSE
NC score	0.035484 (rank : 23)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	74	Target Neighborhood Hits	162	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ZF106_HUMAN
NC score	0.035003 (rank : 24)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	74	Target Neighborhood Hits	470	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

PITM1_MOUSE
NC score	0.034586 (rank : 25)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O35954	Gene names	Pitpnm1, Dres9, Mpt1, Nir2, Pitpnm
Domain Architecture	No domain graphic available
Description	Membrane-associated phosphatidylinositol transfer protein 1 (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Mpt-1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) (Drosophila retinal degeneration B homolog 1) (RdgB1).

GRIPE_HUMAN
NC score	0.031722 (rank : 26)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	74	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYQ0, O94960, Q6GYP9, Q6ZT23, Q86YF3, Q86YF5, Q8ND69	Gene names	GARNL1, KIAA0884, TULIP1
Domain Architecture	No domain graphic available
Description	GTPase-activating Rap/Ran-GAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

RIMB1_HUMAN
NC score	0.031472 (rank : 27)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	74	Target Neighborhood Hits	1479	Shared Neighborhood Hits	14
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RRBP1_MOUSE
NC score	0.030128 (rank : 28)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	74	Target Neighborhood Hits	1650	Shared Neighborhood Hits	18
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

TR150_HUMAN
NC score	0.029480 (rank : 29)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	74	Target Neighborhood Hits	313	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

JPH2_HUMAN
NC score	0.029395 (rank : 30)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	74	Target Neighborhood Hits	639	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BR39, O95913, Q5JY74, Q9UJN4	Gene names	JPH2, JP2
Domain Architecture
Description	Junctophilin-2 (Junctophilin type 2) (JP-2).

GASP2_MOUSE
NC score	0.029070 (rank : 31)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	74	Target Neighborhood Hits	228	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUY8	Gene names	Gprasp2
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor-associated sorting protein 2 (GASP-2).

MUC1_HUMAN
NC score	0.028176 (rank : 32)	θ value	0.0148317 (rank : 9)
Query Neighborhood Hits	74	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

SODE_MOUSE
NC score	0.027758 (rank : 33)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	74	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	O09164	Gene names	Sod3
Domain Architecture
Description	Extracellular superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1) (EC-SOD).

ZF106_MOUSE
NC score	0.027417 (rank : 34)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	74	Target Neighborhood Hits	472	Shared Neighborhood Hits	12
SwissProt Accessions	O88466, O55185, O88465, O88467, Q792M1, Q792P4, Q8CDZ8, Q8R3I4, Q9ESU3	Gene names	Zfp106, H3a, Sh3bp3, Sirm, Znf474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 (Zfp-106) (Zinc finger protein 474) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant).

TGON2_HUMAN
NC score	0.027322 (rank : 35)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	74	Target Neighborhood Hits	1037	Shared Neighborhood Hits	27
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

IQGA1_HUMAN
NC score	0.026897 (rank : 36)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	74	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	P46940	Gene names	IQGAP1, KIAA0051
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP1 (p195).

ELOA2_HUMAN
NC score	0.025953 (rank : 37)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	74	Target Neighborhood Hits	165	Shared Neighborhood Hits	9
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

NFH_MOUSE
NC score	0.023146 (rank : 38)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	74	Target Neighborhood Hits	2247	Shared Neighborhood Hits	30
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

GRIPE_MOUSE
NC score	0.023046 (rank : 39)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	74	Target Neighborhood Hits	70	Shared Neighborhood Hits	4
SwissProt Accessions	Q6GYP7, Q6GYP6, Q6ZQ28, Q8BNJ5, Q8C9G8, Q8CIW4, Q9JMC4	Gene names	Garnl1, Kiaa0884, Tulip1
Domain Architecture	No domain graphic available
Description	GTPase-activating RapGAP domain-like 1 (GAP-related-interacting partner to E12) (GRIPE) (Tuberin-like protein 1).

GA2L2_HUMAN
NC score	0.021464 (rank : 40)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	74	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NHY3, Q8NHY4	Gene names	GAS2L2, GAR17
Domain Architecture	No domain graphic available
Description	GAS2-like protein 2 (Growth arrest-specific 2-like 2) (GAS2-related protein on chromosome 17) (GAR17 protein).

SCG2_HUMAN
NC score	0.021238 (rank : 41)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	74	Target Neighborhood Hits	190	Shared Neighborhood Hits	6
SwissProt Accessions	P13521, Q8TBH3	Gene names	SCG2, CHGC
Domain Architecture
Description	Secretogranin-2 precursor (Secretogranin II) (SgII) (Chromogranin C) [Contains: Secretoneurin (SN)].

CL026_MOUSE
NC score	0.019467 (rank : 42)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	74	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NXH8, Q3UMX5	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C12orf26 homolog.

JUNB_MOUSE
NC score	0.018384 (rank : 43)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	74	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P09450, Q8C2G9	Gene names	Junb, Jun-b
Domain Architecture
Description	Transcription factor jun-B.

PDZD2_HUMAN
NC score	0.018176 (rank : 44)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	74	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

FAIM2_HUMAN
NC score	0.018090 (rank : 45)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	74	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWQ8, Q9UJY9, Q9Y2F7	Gene names	FAIM2, KIAA0950, LFG, TMBIM2
Domain Architecture
Description	Fas apoptotic inhibitory molecule 2 (Lifeguard protein) (Transmembrane BAX inhibitor motif-containing protein 2).

DACT1_MOUSE
NC score	0.017574 (rank : 46)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	74	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

RBBP6_HUMAN
NC score	0.017338 (rank : 47)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	74	Target Neighborhood Hits	1135	Shared Neighborhood Hits	17
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FILA_HUMAN
NC score	0.016739 (rank : 48)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	74	Target Neighborhood Hits	685	Shared Neighborhood Hits	16
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

NKTR_HUMAN
NC score	0.016101 (rank : 49)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	74	Target Neighborhood Hits	658	Shared Neighborhood Hits	14
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

IQEC3_MOUSE
NC score	0.016010 (rank : 50)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	74	Target Neighborhood Hits	274	Shared Neighborhood Hits	12
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

PSIP1_MOUSE
NC score	0.015937 (rank : 51)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	74	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

RP3A_MOUSE
NC score	0.015926 (rank : 52)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	74	Target Neighborhood Hits	510	Shared Neighborhood Hits	14
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

MEF2B_MOUSE
NC score	0.015332 (rank : 53)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	74	Target Neighborhood Hits	218	Shared Neighborhood Hits	5
SwissProt Accessions	O55087, O55088, O55089, O55090, O55231, Q61843	Gene names	Mef2b
Domain Architecture
Description	Myocyte-specific enhancer factor 2B.

CSKI1_MOUSE
NC score	0.014191 (rank : 54)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	74	Target Neighborhood Hits	1031	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LAMA2_HUMAN
NC score	0.012854 (rank : 55)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	74	Target Neighborhood Hits	1092	Shared Neighborhood Hits	7
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

RFIP5_MOUSE
NC score	0.012807 (rank : 56)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	74	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R361	Gene names	Rab11fip5, D6Ertd32e, Rip11
Domain Architecture	No domain graphic available
Description	Rab11 family-interacting protein 5 (Rab11-FIP5) (Rab11-interacting protein Rip11).

JHD3B_HUMAN
NC score	0.010393 (rank : 57)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	74	Target Neighborhood Hits	128	Shared Neighborhood Hits	5
SwissProt Accessions	O94953, O75274, Q6P3R5, Q9P1V1, Q9UF40	Gene names	JMJD2B, JHDM3B, KIAA0876
Domain Architecture
Description	JmjC domain-containing histone demethylation protein 3B (EC 1.14.11.-) (Jumonji domain-containing protein 2B).

BRWD1_HUMAN
NC score	0.010352 (rank : 58)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	74	Target Neighborhood Hits	448	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSI6, O43721, Q5R2V0, Q5R2V1, Q8TCV3, Q96QG9, Q96QH0, Q9NUK1	Gene names	BRWD1, C21orf107, WDR9
Domain Architecture
Description	Bromodomain and WD repeat domain-containing protein 1 (WD repeat protein 9).

K0317_HUMAN
NC score	0.009742 (rank : 59)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	74	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O15033, Q7LDY1, Q8IYY9	Gene names	KIAA0317
Domain Architecture	No domain graphic available
Description	Protein KIAA0317.

ALMS1_HUMAN
NC score	0.009617 (rank : 60)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	74	Target Neighborhood Hits	356	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

PHLPP_HUMAN
NC score	0.009570 (rank : 61)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	74	Target Neighborhood Hits	604	Shared Neighborhood Hits	12
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

SEPT9_HUMAN
NC score	0.008986 (rank : 62)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	74	Target Neighborhood Hits	706	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

NOS1_HUMAN
NC score	0.008955 (rank : 63)	θ value	5.27518 (rank : 60)
Query Neighborhood Hits	74	Target Neighborhood Hits	218	Shared Neighborhood Hits	4
SwissProt Accessions	P29475	Gene names	NOS1
Domain Architecture
Description	Nitric-oxide synthase, brain (EC 1.14.13.39) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Constitutive NOS) (NC-NOS) (bNOS).

MEFV_HUMAN
NC score	0.008656 (rank : 64)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	74	Target Neighborhood Hits	431	Shared Neighborhood Hits	7
SwissProt Accessions	O15553, Q96PN4, Q96PN5	Gene names	MEFV, MEF
Domain Architecture
Description	Pyrin (Marenostrin).

CAC1A_HUMAN
NC score	0.008615 (rank : 65)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	74	Target Neighborhood Hits	387	Shared Neighborhood Hits	14
SwissProt Accessions	O00555, P78510, P78511, Q16290, Q92690, Q99790, Q99791, Q99792, Q99793	Gene names	CACNA1A, CACH4, CACN3, CACNL1A4
Domain Architecture
Description	Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage- gated calcium channel subunit alpha Cav2.1) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Brain calcium channel I) (BI).

P2RX2_HUMAN
NC score	0.008273 (rank : 66)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	74	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBL9, Q6V9R6, Q9NR37, Q9NR38, Q9UHD5, Q9UHD6, Q9UHD7, Q9Y637, Q9Y638	Gene names	P2RX2, P2X2
Domain Architecture
Description	P2X purinoceptor 2 (ATP receptor) (P2X2) (Purinergic receptor).

CDC20_HUMAN
NC score	0.008183 (rank : 67)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	74	Target Neighborhood Hits	329	Shared Neighborhood Hits	9
SwissProt Accessions	Q12834, Q9BW56, Q9UQI9	Gene names	CDC20
Domain Architecture
Description	Cell division cycle protein 20 homolog (p55CDC).

FREM3_HUMAN
NC score	0.008070 (rank : 68)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	74	Target Neighborhood Hits	56	Shared Neighborhood Hits	2
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

SPEG_HUMAN
NC score	0.005269 (rank : 69)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	74	Target Neighborhood Hits	1762	Shared Neighborhood Hits	19
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

PAK6_HUMAN
NC score	0.005218 (rank : 70)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	74	Target Neighborhood Hits	915	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

RAB23_MOUSE
NC score	0.004501 (rank : 71)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	74	Target Neighborhood Hits	274	Shared Neighborhood Hits	3
SwissProt Accessions	P35288	Gene names	Rab23
Domain Architecture
Description	Ras-related protein Rab-23 (Rab-15).

MYLK_MOUSE
NC score	0.003637 (rank : 72)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	74	Target Neighborhood Hits	1489	Shared Neighborhood Hits	9
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

LTBP2_MOUSE
NC score	0.003516 (rank : 73)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	74	Target Neighborhood Hits	617	Shared Neighborhood Hits	7
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

S6A17_HUMAN
NC score	0.003064 (rank : 74)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	74	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H1V8, Q5T5Q9	Gene names	SLC6A17, NTT4
Domain Architecture	No domain graphic available
Description	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT4 (Solute carrier family 6 member 17).