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Network neighborhood for query Sequence : IQEC3_MOUSE

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IQEC3_MOUSE
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IQEC3_HUMAN
θ value	0 (rank : 1)	NC score	0.968732 (rank : 2)
Query Neighborhood Hits	274	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	274	Target Neighborhood Hits	274	Shared Neighborhood Hits	274
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC1_HUMAN
θ value	1.19867e-161 (rank : 3)	NC score	0.951828 (rank : 4)
Query Neighborhood Hits	274	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	6.83811e-141 (rank : 4)	NC score	0.952424 (rank : 3)
Query Neighborhood Hits	274	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_HUMAN
θ value	3.76091e-131 (rank : 5)	NC score	0.916929 (rank : 5)
Query Neighborhood Hits	274	Target Neighborhood Hits	403	Shared Neighborhood Hits	68
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	1.09426e-130 (rank : 6)	NC score	0.916052 (rank : 6)
Query Neighborhood Hits	274	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

CYH2_HUMAN
θ value	3.37985e-39 (rank : 7)	NC score	0.800094 (rank : 10)
Query Neighborhood Hits	274	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	4.41421e-39 (rank : 8)	NC score	0.800378 (rank : 9)
Query Neighborhood Hits	274	Target Neighborhood Hits	171	Shared Neighborhood Hits	27
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH1_MOUSE
θ value	1.6774e-38 (rank : 9)	NC score	0.793022 (rank : 13)
Query Neighborhood Hits	274	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_HUMAN
θ value	2.86122e-38 (rank : 10)	NC score	0.796078 (rank : 12)
Query Neighborhood Hits	274	Target Neighborhood Hits	137	Shared Neighborhood Hits	28
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_HUMAN
θ value	3.73686e-38 (rank : 11)	NC score	0.790334 (rank : 17)
Query Neighborhood Hits	274	Target Neighborhood Hits	184	Shared Neighborhood Hits	28
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_MOUSE
θ value	4.88048e-38 (rank : 12)	NC score	0.790930 (rank : 14)
Query Neighborhood Hits	274	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

BIG1_HUMAN
θ value	3.4976e-36 (rank : 13)	NC score	0.814410 (rank : 8)
Query Neighborhood Hits	274	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CYH4_MOUSE
θ value	2.12192e-33 (rank : 14)	NC score	0.790897 (rank : 15)
Query Neighborhood Hits	274	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
θ value	2.34606e-32 (rank : 15)	NC score	0.790345 (rank : 16)
Query Neighborhood Hits	274	Target Neighborhood Hits	135	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

BIG2_HUMAN
θ value	4.42448e-31 (rank : 16)	NC score	0.797991 (rank : 11)
Query Neighborhood Hits	274	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

GBF1_HUMAN
θ value	1.85889e-29 (rank : 17)	NC score	0.819649 (rank : 7)
Query Neighborhood Hits	274	Target Neighborhood Hits	142	Shared Neighborhood Hits	45
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

FBX8_HUMAN
θ value	3.28887e-18 (rank : 18)	NC score	0.775906 (rank : 19)
Query Neighborhood Hits	274	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	9.56915e-18 (rank : 19)	NC score	0.777222 (rank : 18)
Query Neighborhood Hits	274	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

PSD3_HUMAN
θ value	1.63225e-17 (rank : 20)	NC score	0.728360 (rank : 20)
Query Neighborhood Hits	274	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_HUMAN
θ value	1.63225e-17 (rank : 21)	NC score	0.696952 (rank : 22)
Query Neighborhood Hits	274	Target Neighborhood Hits	178	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	2.7842e-17 (rank : 22)	NC score	0.697697 (rank : 21)
Query Neighborhood Hits	274	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

WNK4_HUMAN
θ value	5.44631e-05 (rank : 23)	NC score	0.022086 (rank : 213)
Query Neighborhood Hits	274	Target Neighborhood Hits	1043	Shared Neighborhood Hits	57
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TNKS1_HUMAN
θ value	0.00020696 (rank : 24)	NC score	0.025793 (rank : 190)
Query Neighborhood Hits	274	Target Neighborhood Hits	477	Shared Neighborhood Hits	35
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

CAC1G_HUMAN
θ value	0.000461057 (rank : 25)	NC score	0.054853 (rank : 95)
Query Neighborhood Hits	274	Target Neighborhood Hits	587	Shared Neighborhood Hits	71
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

RGS3_MOUSE
θ value	0.00390308 (rank : 26)	NC score	0.077994 (rank : 51)
Query Neighborhood Hits	274	Target Neighborhood Hits	1621	Shared Neighborhood Hits	143
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

BASP_HUMAN
θ value	0.00665767 (rank : 27)	NC score	0.104429 (rank : 36)
Query Neighborhood Hits	274	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

OGFR_HUMAN
θ value	0.00869519 (rank : 28)	NC score	0.094439 (rank : 41)
Query Neighborhood Hits	274	Target Neighborhood Hits	1582	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

BASP_MOUSE
θ value	0.0113563 (rank : 29)	NC score	0.100365 (rank : 38)
Query Neighborhood Hits	274	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

ATX7_HUMAN
θ value	0.0193708 (rank : 30)	NC score	0.082464 (rank : 50)
Query Neighborhood Hits	274	Target Neighborhood Hits	351	Shared Neighborhood Hits	65
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

SELPL_MOUSE
θ value	0.0193708 (rank : 31)	NC score	0.074449 (rank : 55)
Query Neighborhood Hits	274	Target Neighborhood Hits	588	Shared Neighborhood Hits	85
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

WNK2_HUMAN
θ value	0.0193708 (rank : 32)	NC score	0.027652 (rank : 180)
Query Neighborhood Hits	274	Target Neighborhood Hits	1407	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

GMIP_HUMAN
θ value	0.0330416 (rank : 33)	NC score	0.022936 (rank : 202)
Query Neighborhood Hits	274	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

HME1_MOUSE
θ value	0.0431538 (rank : 34)	NC score	0.021824 (rank : 215)
Query Neighborhood Hits	274	Target Neighborhood Hits	397	Shared Neighborhood Hits	27
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

SAPS1_HUMAN
θ value	0.0431538 (rank : 35)	NC score	0.056791 (rank : 90)
Query Neighborhood Hits	274	Target Neighborhood Hits	704	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

BSN_MOUSE
θ value	0.0563607 (rank : 36)	NC score	0.092079 (rank : 44)
Query Neighborhood Hits	274	Target Neighborhood Hits	2057	Shared Neighborhood Hits	168
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

IWS1_MOUSE
θ value	0.0563607 (rank : 37)	NC score	0.049619 (rank : 130)
Query Neighborhood Hits	274	Target Neighborhood Hits	1258	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MILK1_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.064860 (rank : 68)
Query Neighborhood Hits	274	Target Neighborhood Hits	788	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

NFH_MOUSE
θ value	0.0563607 (rank : 39)	NC score	0.062524 (rank : 75)
Query Neighborhood Hits	274	Target Neighborhood Hits	2247	Shared Neighborhood Hits	162
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

ATS13_HUMAN
θ value	0.0961366 (rank : 40)	NC score	0.017090 (rank : 245)
Query Neighborhood Hits	274	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

DYNA_HUMAN
θ value	0.0961366 (rank : 41)	NC score	0.018487 (rank : 236)
Query Neighborhood Hits	274	Target Neighborhood Hits	1194	Shared Neighborhood Hits	50
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

ZN750_MOUSE
θ value	0.0961366 (rank : 42)	NC score	0.051429 (rank : 118)
Query Neighborhood Hits	274	Target Neighborhood Hits	346	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

FMN1B_MOUSE
θ value	0.125558 (rank : 43)	NC score	0.041297 (rank : 144)
Query Neighborhood Hits	274	Target Neighborhood Hits	447	Shared Neighborhood Hits	65
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

RERE_MOUSE
θ value	0.125558 (rank : 44)	NC score	0.054269 (rank : 99)
Query Neighborhood Hits	274	Target Neighborhood Hits	785	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

BSN_HUMAN
θ value	0.163984 (rank : 45)	NC score	0.077444 (rank : 54)
Query Neighborhood Hits	274	Target Neighborhood Hits	1537	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

FARP1_HUMAN
θ value	0.163984 (rank : 46)	NC score	0.054579 (rank : 97)
Query Neighborhood Hits	274	Target Neighborhood Hits	241	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

HGS_MOUSE
θ value	0.163984 (rank : 47)	NC score	0.041334 (rank : 142)
Query Neighborhood Hits	274	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

HME1_HUMAN
θ value	0.163984 (rank : 48)	NC score	0.020531 (rank : 221)
Query Neighborhood Hits	274	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

KLF14_HUMAN
θ value	0.163984 (rank : 49)	NC score	0.001300 (rank : 327)
Query Neighborhood Hits	274	Target Neighborhood Hits	725	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

MLL3_HUMAN
θ value	0.163984 (rank : 50)	NC score	0.066312 (rank : 65)
Query Neighborhood Hits	274	Target Neighborhood Hits	1644	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SFPQ_HUMAN
θ value	0.163984 (rank : 51)	NC score	0.045797 (rank : 136)
Query Neighborhood Hits	274	Target Neighborhood Hits	986	Shared Neighborhood Hits	83
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SPEG_HUMAN
θ value	0.163984 (rank : 52)	NC score	0.013006 (rank : 266)
Query Neighborhood Hits	274	Target Neighborhood Hits	1762	Shared Neighborhood Hits	99
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TP53B_MOUSE
θ value	0.163984 (rank : 53)	NC score	0.053879 (rank : 102)
Query Neighborhood Hits	274	Target Neighborhood Hits	644	Shared Neighborhood Hits	64
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MSH3_HUMAN
θ value	0.21417 (rank : 54)	NC score	0.022208 (rank : 210)
Query Neighborhood Hits	274	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

PKD1_HUMAN
θ value	0.21417 (rank : 55)	NC score	0.020458 (rank : 222)
Query Neighborhood Hits	274	Target Neighborhood Hits	387	Shared Neighborhood Hits	10
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

RGS3_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.064390 (rank : 69)
Query Neighborhood Hits	274	Target Neighborhood Hits	1375	Shared Neighborhood Hits	120
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SEPT9_HUMAN
θ value	0.21417 (rank : 57)	NC score	0.034393 (rank : 160)
Query Neighborhood Hits	274	Target Neighborhood Hits	706	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

CRSP2_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.062984 (rank : 74)
Query Neighborhood Hits	274	Target Neighborhood Hits	380	Shared Neighborhood Hits	63
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

FGD4_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.052798 (rank : 108)
Query Neighborhood Hits	274	Target Neighborhood Hits	219	Shared Neighborhood Hits	24
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

IER5_MOUSE
θ value	0.279714 (rank : 60)	NC score	0.045090 (rank : 137)
Query Neighborhood Hits	274	Target Neighborhood Hits	110	Shared Neighborhood Hits	23
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

IWS1_HUMAN
θ value	0.279714 (rank : 61)	NC score	0.047254 (rank : 134)
Query Neighborhood Hits	274	Target Neighborhood Hits	1241	Shared Neighborhood Hits	78
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MAST4_HUMAN
θ value	0.279714 (rank : 62)	NC score	0.019807 (rank : 227)
Query Neighborhood Hits	274	Target Neighborhood Hits	1804	Shared Neighborhood Hits	112
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NRX2A_HUMAN
θ value	0.279714 (rank : 63)	NC score	0.036304 (rank : 153)
Query Neighborhood Hits	274	Target Neighborhood Hits	614	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.279714 (rank : 64)	NC score	0.053480 (rank : 104)
Query Neighborhood Hits	274	Target Neighborhood Hits	481	Shared Neighborhood Hits	62
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SALL3_HUMAN
θ value	0.279714 (rank : 65)	NC score	0.010012 (rank : 285)
Query Neighborhood Hits	274	Target Neighborhood Hits	1066	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZIC5_HUMAN
θ value	0.279714 (rank : 66)	NC score	0.001126 (rank : 328)
Query Neighborhood Hits	274	Target Neighborhood Hits	774	Shared Neighborhood Hits	29
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

FOXGA_HUMAN
θ value	0.365318 (rank : 67)	NC score	0.018798 (rank : 235)
Query Neighborhood Hits	274	Target Neighborhood Hits	132	Shared Neighborhood Hits	18
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

IMMT_MOUSE
θ value	0.365318 (rank : 68)	NC score	0.035315 (rank : 156)
Query Neighborhood Hits	274	Target Neighborhood Hits	326	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

MYO15_MOUSE
θ value	0.365318 (rank : 69)	NC score	0.016185 (rank : 250)
Query Neighborhood Hits	274	Target Neighborhood Hits	467	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PI5PA_MOUSE
θ value	0.365318 (rank : 70)	NC score	0.037747 (rank : 151)
Query Neighborhood Hits	274	Target Neighborhood Hits	331	Shared Neighborhood Hits	59
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

TCOF_HUMAN
θ value	0.365318 (rank : 71)	NC score	0.059506 (rank : 82)
Query Neighborhood Hits	274	Target Neighborhood Hits	543	Shared Neighborhood Hits	64
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TGON2_HUMAN
θ value	0.365318 (rank : 72)	NC score	0.049482 (rank : 131)
Query Neighborhood Hits	274	Target Neighborhood Hits	1037	Shared Neighborhood Hits	89
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1G_HUMAN
θ value	0.365318 (rank : 73)	NC score	0.024822 (rank : 194)
Query Neighborhood Hits	274	Target Neighborhood Hits	410	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	0.365318 (rank : 74)	NC score	0.027653 (rank : 179)
Query Neighborhood Hits	274	Target Neighborhood Hits	498	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

VTNC_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.018176 (rank : 240)
Query Neighborhood Hits	274	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

ZN207_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.057471 (rank : 88)
Query Neighborhood Hits	274	Target Neighborhood Hits	326	Shared Neighborhood Hits	34
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

CLIC6_HUMAN
θ value	0.47712 (rank : 77)	NC score	0.028430 (rank : 177)
Query Neighborhood Hits	274	Target Neighborhood Hits	289	Shared Neighborhood Hits	35
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

FGD4_MOUSE
θ value	0.47712 (rank : 78)	NC score	0.051695 (rank : 116)
Query Neighborhood Hits	274	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

HMX2_MOUSE
θ value	0.47712 (rank : 79)	NC score	0.012173 (rank : 273)
Query Neighborhood Hits	274	Target Neighborhood Hits	354	Shared Neighborhood Hits	14
SwissProt Accessions	P43687, Q8R1Q2	Gene names	Hmx2, Nkx-5.2, Nkx5-2
Domain Architecture
Description	Homeobox protein HMX2 (Homeobox protein Nkx-5.2).

IMMT_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.031031 (rank : 170)
Query Neighborhood Hits	274	Target Neighborhood Hits	494	Shared Neighborhood Hits	27
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

MEGF9_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.020624 (rank : 219)
Query Neighborhood Hits	274	Target Neighborhood Hits	557	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

NGAP_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.016336 (rank : 247)
Query Neighborhood Hits	274	Target Neighborhood Hits	517	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

CYTSA_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.014883 (rank : 257)
Query Neighborhood Hits	274	Target Neighborhood Hits	1104	Shared Neighborhood Hits	32
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

FOSB_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.024356 (rank : 196)
Query Neighborhood Hits	274	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

GCC2_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.009693 (rank : 288)
Query Neighborhood Hits	274	Target Neighborhood Hits	1619	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

HXA13_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.016196 (rank : 249)
Query Neighborhood Hits	274	Target Neighborhood Hits	353	Shared Neighborhood Hits	21
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

K1802_HUMAN
θ value	0.62314 (rank : 87)	NC score	0.052301 (rank : 114)
Query Neighborhood Hits	274	Target Neighborhood Hits	1378	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PCLO_MOUSE
θ value	0.62314 (rank : 88)	NC score	0.066733 (rank : 63)
Query Neighborhood Hits	274	Target Neighborhood Hits	2275	Shared Neighborhood Hits	168
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PGCB_HUMAN
θ value	0.62314 (rank : 89)	NC score	0.013009 (rank : 265)
Query Neighborhood Hits	274	Target Neighborhood Hits	478	Shared Neighborhood Hits	33
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PTN23_HUMAN
θ value	0.62314 (rank : 90)	NC score	0.033095 (rank : 164)
Query Neighborhood Hits	274	Target Neighborhood Hits	646	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

TBX1_HUMAN
θ value	0.62314 (rank : 91)	NC score	0.009452 (rank : 290)
Query Neighborhood Hits	274	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

THAP4_HUMAN
θ value	0.62314 (rank : 92)	NC score	0.027231 (rank : 181)
Query Neighborhood Hits	274	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

FGD6_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.051236 (rank : 120)
Query Neighborhood Hits	274	Target Neighborhood Hits	237	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.051220 (rank : 121)
Query Neighborhood Hits	274	Target Neighborhood Hits	282	Shared Neighborhood Hits	33
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

GRIN1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.054686 (rank : 96)
Query Neighborhood Hits	274	Target Neighborhood Hits	681	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MIS_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.019105 (rank : 232)
Query Neighborhood Hits	274	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

MKL1_MOUSE
θ value	0.813845 (rank : 97)	NC score	0.058211 (rank : 86)
Query Neighborhood Hits	274	Target Neighborhood Hits	667	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MYO3A_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.003622 (rank : 318)
Query Neighborhood Hits	274	Target Neighborhood Hits	1033	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

NSMA2_MOUSE
θ value	0.813845 (rank : 99)	NC score	0.034121 (rank : 162)
Query Neighborhood Hits	274	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

PSL1_HUMAN
θ value	0.813845 (rank : 100)	NC score	0.054517 (rank : 98)
Query Neighborhood Hits	274	Target Neighborhood Hits	650	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PTN23_MOUSE
θ value	0.813845 (rank : 101)	NC score	0.030704 (rank : 172)
Query Neighborhood Hits	274	Target Neighborhood Hits	726	Shared Neighborhood Hits	85
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

SMOO_HUMAN
θ value	0.813845 (rank : 102)	NC score	0.048430 (rank : 132)
Query Neighborhood Hits	274	Target Neighborhood Hits	391	Shared Neighborhood Hits	65
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

CHMP6_MOUSE
θ value	1.06291 (rank : 103)	NC score	0.022749 (rank : 203)
Query Neighborhood Hits	274	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	P0C0A3	Gene names	Chmp6
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6).

EP300_HUMAN
θ value	1.06291 (rank : 104)	NC score	0.061618 (rank : 77)
Query Neighborhood Hits	274	Target Neighborhood Hits	821	Shared Neighborhood Hits	96
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GMEB2_HUMAN
θ value	1.06291 (rank : 105)	NC score	0.017272 (rank : 244)
Query Neighborhood Hits	274	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

HGS_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.033715 (rank : 163)
Query Neighborhood Hits	274	Target Neighborhood Hits	517	Shared Neighborhood Hits	47
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HSF2_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.030826 (rank : 171)
Query Neighborhood Hits	274	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HSF2_MOUSE
θ value	1.06291 (rank : 108)	NC score	0.031203 (rank : 169)
Query Neighborhood Hits	274	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

HXA13_MOUSE
θ value	1.06291 (rank : 109)	NC score	0.015075 (rank : 256)
Query Neighborhood Hits	274	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

K1802_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.063873 (rank : 72)
Query Neighborhood Hits	274	Target Neighborhood Hits	1596	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MLL2_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.048420 (rank : 133)
Query Neighborhood Hits	274	Target Neighborhood Hits	1788	Shared Neighborhood Hits	130
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SREC2_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.016972 (rank : 246)
Query Neighborhood Hits	274	Target Neighborhood Hits	645	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

ABCA2_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.005459 (rank : 314)
Query Neighborhood Hits	274	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

CBLB_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.020322 (rank : 223)
Query Neighborhood Hits	274	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

CBLB_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.020819 (rank : 218)
Query Neighborhood Hits	274	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

CN155_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.063681 (rank : 73)
Query Neighborhood Hits	274	Target Neighborhood Hits	385	Shared Neighborhood Hits	53
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CYTSA_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.016312 (rank : 248)
Query Neighborhood Hits	274	Target Neighborhood Hits	1138	Shared Neighborhood Hits	47
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

ERCC5_MOUSE
θ value	1.38821 (rank : 118)	NC score	0.034276 (rank : 161)
Query Neighborhood Hits	274	Target Neighborhood Hits	206	Shared Neighborhood Hits	22
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

FOXP4_MOUSE
θ value	1.38821 (rank : 119)	NC score	0.020590 (rank : 220)
Query Neighborhood Hits	274	Target Neighborhood Hits	211	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

FOXQ1_MOUSE
θ value	1.38821 (rank : 120)	NC score	0.011717 (rank : 275)
Query Neighborhood Hits	274	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	O70220	Gene names	Foxq1, Hfh1, Hfh1l
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1) (HFH-1l).

GGN_HUMAN
θ value	1.38821 (rank : 121)	NC score	0.077819 (rank : 52)
Query Neighborhood Hits	274	Target Neighborhood Hits	269	Shared Neighborhood Hits	52
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

GRIN1_MOUSE
θ value	1.38821 (rank : 122)	NC score	0.050874 (rank : 123)
Query Neighborhood Hits	274	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MNT_HUMAN
θ value	1.38821 (rank : 123)	NC score	0.041949 (rank : 140)
Query Neighborhood Hits	274	Target Neighborhood Hits	496	Shared Neighborhood Hits	73
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SC24C_HUMAN
θ value	1.38821 (rank : 124)	NC score	0.046749 (rank : 135)
Query Neighborhood Hits	274	Target Neighborhood Hits	662	Shared Neighborhood Hits	91
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

UBQL3_HUMAN
θ value	1.38821 (rank : 125)	NC score	0.019497 (rank : 230)
Query Neighborhood Hits	274	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

CSKI1_HUMAN
θ value	1.81305 (rank : 126)	NC score	0.029536 (rank : 175)
Query Neighborhood Hits	274	Target Neighborhood Hits	997	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_MOUSE
θ value	1.81305 (rank : 127)	NC score	0.026634 (rank : 186)
Query Neighborhood Hits	274	Target Neighborhood Hits	812	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CUTL1_MOUSE
θ value	1.81305 (rank : 128)	NC score	0.019830 (rank : 226)
Query Neighborhood Hits	274	Target Neighborhood Hits	1620	Shared Neighborhood Hits	80
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DACT1_HUMAN
θ value	1.81305 (rank : 129)	NC score	0.038829 (rank : 148)
Query Neighborhood Hits	274	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

HCN2_MOUSE
θ value	1.81305 (rank : 130)	NC score	0.023945 (rank : 198)
Query Neighborhood Hits	274	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

MAST2_HUMAN
θ value	1.81305 (rank : 131)	NC score	0.004951 (rank : 317)
Query Neighborhood Hits	274	Target Neighborhood Hits	1189	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MBB1A_HUMAN
θ value	1.81305 (rank : 132)	NC score	0.039568 (rank : 147)
Query Neighborhood Hits	274	Target Neighborhood Hits	665	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MEGF9_MOUSE
θ value	1.81305 (rank : 133)	NC score	0.025668 (rank : 192)
Query Neighborhood Hits	274	Target Neighborhood Hits	896	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

OTU7A_HUMAN
θ value	1.81305 (rank : 134)	NC score	0.016010 (rank : 251)
Query Neighborhood Hits	274	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

PCQAP_HUMAN
θ value	1.81305 (rank : 135)	NC score	0.041311 (rank : 143)
Query Neighborhood Hits	274	Target Neighborhood Hits	549	Shared Neighborhood Hits	59
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

RUSC2_HUMAN
θ value	1.81305 (rank : 136)	NC score	0.022411 (rank : 207)
Query Neighborhood Hits	274	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

SIRT1_HUMAN
θ value	1.81305 (rank : 137)	NC score	0.014025 (rank : 260)
Query Neighborhood Hits	274	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

SRRM2_MOUSE
θ value	1.81305 (rank : 138)	NC score	0.052376 (rank : 113)
Query Neighborhood Hits	274	Target Neighborhood Hits	1470	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AKA12_HUMAN
θ value	2.36792 (rank : 139)	NC score	0.032522 (rank : 166)
Query Neighborhood Hits	274	Target Neighborhood Hits	825	Shared Neighborhood Hits	51
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ANKS1_HUMAN
θ value	2.36792 (rank : 140)	NC score	0.012710 (rank : 271)
Query Neighborhood Hits	274	Target Neighborhood Hits	438	Shared Neighborhood Hits	17
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANR11_HUMAN
θ value	2.36792 (rank : 141)	NC score	0.027035 (rank : 182)
Query Neighborhood Hits	274	Target Neighborhood Hits	1289	Shared Neighborhood Hits	85
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ARI1A_HUMAN
θ value	2.36792 (rank : 142)	NC score	0.038139 (rank : 149)
Query Neighborhood Hits	274	Target Neighborhood Hits	787	Shared Neighborhood Hits	82
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

ATX2L_HUMAN
θ value	2.36792 (rank : 143)	NC score	0.053619 (rank : 103)
Query Neighborhood Hits	274	Target Neighborhood Hits	443	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CIC_HUMAN
θ value	2.36792 (rank : 144)	NC score	0.043477 (rank : 138)
Query Neighborhood Hits	274	Target Neighborhood Hits	992	Shared Neighborhood Hits	115
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CK5P2_MOUSE
θ value	2.36792 (rank : 145)	NC score	0.009976 (rank : 286)
Query Neighborhood Hits	274	Target Neighborhood Hits	1151	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

FA47B_HUMAN
θ value	2.36792 (rank : 146)	NC score	0.056478 (rank : 92)
Query Neighborhood Hits	274	Target Neighborhood Hits	431	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GGN_MOUSE
θ value	2.36792 (rank : 147)	NC score	0.061537 (rank : 78)
Query Neighborhood Hits	274	Target Neighborhood Hits	311	Shared Neighborhood Hits	63
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

NMDE4_HUMAN
θ value	2.36792 (rank : 148)	NC score	0.008562 (rank : 295)
Query Neighborhood Hits	274	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

PHLPP_HUMAN
θ value	2.36792 (rank : 149)	NC score	0.021640 (rank : 217)
Query Neighborhood Hits	274	Target Neighborhood Hits	604	Shared Neighborhood Hits	55
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

RANB9_HUMAN
θ value	2.36792 (rank : 150)	NC score	0.031410 (rank : 168)
Query Neighborhood Hits	274	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

RIMB1_HUMAN
θ value	2.36792 (rank : 151)	NC score	0.034593 (rank : 159)
Query Neighborhood Hits	274	Target Neighborhood Hits	1479	Shared Neighborhood Hits	96
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RP3A_MOUSE
θ value	2.36792 (rank : 152)	NC score	0.029669 (rank : 174)
Query Neighborhood Hits	274	Target Neighborhood Hits	510	Shared Neighborhood Hits	70
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SASH1_HUMAN
θ value	2.36792 (rank : 153)	NC score	0.022155 (rank : 211)
Query Neighborhood Hits	274	Target Neighborhood Hits	292	Shared Neighborhood Hits	38
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

SON_HUMAN
θ value	2.36792 (rank : 154)	NC score	0.060221 (rank : 81)
Query Neighborhood Hits	274	Target Neighborhood Hits	1568	Shared Neighborhood Hits	141
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TACC3_HUMAN
θ value	2.36792 (rank : 155)	NC score	0.026745 (rank : 185)
Query Neighborhood Hits	274	Target Neighborhood Hits	779	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

ZN592_MOUSE
θ value	2.36792 (rank : 156)	NC score	0.001866 (rank : 324)
Query Neighborhood Hits	274	Target Neighborhood Hits	768	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ARHGA_HUMAN
θ value	3.0926 (rank : 157)	NC score	0.020309 (rank : 224)
Query Neighborhood Hits	274	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ASPM_MOUSE
θ value	3.0926 (rank : 158)	NC score	0.018990 (rank : 233)
Query Neighborhood Hits	274	Target Neighborhood Hits	150	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

CEBPE_HUMAN
θ value	3.0926 (rank : 159)	NC score	0.019717 (rank : 228)
Query Neighborhood Hits	274	Target Neighborhood Hits	236	Shared Neighborhood Hits	25
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

CI082_MOUSE
θ value	3.0926 (rank : 160)	NC score	0.030511 (rank : 173)
Query Neighborhood Hits	274	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDY9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82 homolog.

CTDP1_HUMAN
θ value	3.0926 (rank : 161)	NC score	0.037084 (rank : 152)
Query Neighborhood Hits	274	Target Neighborhood Hits	416	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

HXD3_MOUSE
θ value	3.0926 (rank : 162)	NC score	0.018424 (rank : 238)
Query Neighborhood Hits	274	Target Neighborhood Hits	435	Shared Neighborhood Hits	31
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

MILK2_HUMAN
θ value	3.0926 (rank : 163)	NC score	0.035549 (rank : 155)
Query Neighborhood Hits	274	Target Neighborhood Hits	457	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NACAM_MOUSE
θ value	3.0926 (rank : 164)	NC score	0.066917 (rank : 61)
Query Neighborhood Hits	274	Target Neighborhood Hits	1866	Shared Neighborhood Hits	157
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PDLI7_MOUSE
θ value	3.0926 (rank : 165)	NC score	0.006161 (rank : 311)
Query Neighborhood Hits	274	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

PHC2_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.035921 (rank : 154)
Query Neighborhood Hits	274	Target Neighborhood Hits	388	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

SHAN1_HUMAN
θ value	3.0926 (rank : 167)	NC score	0.025153 (rank : 193)
Query Neighborhood Hits	274	Target Neighborhood Hits	1041	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SPR1B_MOUSE
θ value	3.0926 (rank : 168)	NC score	0.061174 (rank : 79)
Query Neighborhood Hits	274	Target Neighborhood Hits	395	Shared Neighborhood Hits	65
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

ZEP2_MOUSE
θ value	3.0926 (rank : 169)	NC score	0.007395 (rank : 301)
Query Neighborhood Hits	274	Target Neighborhood Hits	964	Shared Neighborhood Hits	52
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

AAK1_MOUSE
θ value	4.03905 (rank : 170)	NC score	0.007033 (rank : 307)
Query Neighborhood Hits	274	Target Neighborhood Hits	1051	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

AATK_HUMAN
θ value	4.03905 (rank : 171)	NC score	0.007475 (rank : 300)
Query Neighborhood Hits	274	Target Neighborhood Hits	1243	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ATBF1_HUMAN
θ value	4.03905 (rank : 172)	NC score	0.014074 (rank : 258)
Query Neighborhood Hits	274	Target Neighborhood Hits	1547	Shared Neighborhood Hits	88
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CEBPD_HUMAN
θ value	4.03905 (rank : 173)	NC score	0.017952 (rank : 242)
Query Neighborhood Hits	274	Target Neighborhood Hits	135	Shared Neighborhood Hits	18
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

CI079_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.054260 (rank : 100)
Query Neighborhood Hits	274	Target Neighborhood Hits	288	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CSKI1_MOUSE
θ value	4.03905 (rank : 175)	NC score	0.034898 (rank : 158)
Query Neighborhood Hits	274	Target Neighborhood Hits	1031	Shared Neighborhood Hits	102
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FARP2_MOUSE
θ value	4.03905 (rank : 176)	NC score	0.041826 (rank : 141)
Query Neighborhood Hits	274	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

HCN4_MOUSE
θ value	4.03905 (rank : 177)	NC score	0.023101 (rank : 201)
Query Neighborhood Hits	274	Target Neighborhood Hits	284	Shared Neighborhood Hits	45
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

HXD3_HUMAN
θ value	4.03905 (rank : 178)	NC score	0.022255 (rank : 209)
Query Neighborhood Hits	274	Target Neighborhood Hits	433	Shared Neighborhood Hits	35
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

NR2E1_MOUSE
θ value	4.03905 (rank : 179)	NC score	0.001455 (rank : 326)
Query Neighborhood Hits	274	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

OXRP_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.015915 (rank : 252)
Query Neighborhood Hits	274	Target Neighborhood Hits	544	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PCLO_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.064996 (rank : 66)
Query Neighborhood Hits	274	Target Neighborhood Hits	2046	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PHLA1_MOUSE
θ value	4.03905 (rank : 182)	NC score	0.022135 (rank : 212)
Query Neighborhood Hits	274	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

PRRT3_HUMAN
θ value	4.03905 (rank : 183)	NC score	0.088716 (rank : 47)
Query Neighborhood Hits	274	Target Neighborhood Hits	998	Shared Neighborhood Hits	126
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PTN22_MOUSE
θ value	4.03905 (rank : 184)	NC score	0.009120 (rank : 294)
Query Neighborhood Hits	274	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRN_MOUSE
θ value	4.03905 (rank : 185)	NC score	0.014050 (rank : 259)
Query Neighborhood Hits	274	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

RIOK2_HUMAN
θ value	4.03905 (rank : 186)	NC score	0.013545 (rank : 263)
Query Neighborhood Hits	274	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

RP3A_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.018809 (rank : 234)
Query Neighborhood Hits	274	Target Neighborhood Hits	305	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

SH22A_MOUSE
θ value	4.03905 (rank : 188)	NC score	0.013408 (rank : 264)
Query Neighborhood Hits	274	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SMC2_HUMAN
θ value	4.03905 (rank : 189)	NC score	0.007235 (rank : 303)
Query Neighborhood Hits	274	Target Neighborhood Hits	1405	Shared Neighborhood Hits	45
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SRBP1_MOUSE
θ value	4.03905 (rank : 190)	NC score	0.024649 (rank : 195)
Query Neighborhood Hits	274	Target Neighborhood Hits	384	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TAF1C_MOUSE
θ value	4.03905 (rank : 191)	NC score	0.021958 (rank : 214)
Query Neighborhood Hits	274	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

THAP4_MOUSE
θ value	4.03905 (rank : 192)	NC score	0.022516 (rank : 206)
Query Neighborhood Hits	274	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

ZN395_HUMAN
θ value	4.03905 (rank : 193)	NC score	0.019986 (rank : 225)
Query Neighborhood Hits	274	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

AN30A_HUMAN
θ value	5.27518 (rank : 194)	NC score	0.012753 (rank : 269)
Query Neighborhood Hits	274	Target Neighborhood Hits	1119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CCD96_HUMAN
θ value	5.27518 (rank : 195)	NC score	0.024298 (rank : 197)
Query Neighborhood Hits	274	Target Neighborhood Hits	595	Shared Neighborhood Hits	50
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CI082_HUMAN
θ value	5.27518 (rank : 196)	NC score	0.026519 (rank : 187)
Query Neighborhood Hits	274	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

CMGA_HUMAN
θ value	5.27518 (rank : 197)	NC score	0.021740 (rank : 216)
Query Neighborhood Hits	274	Target Neighborhood Hits	238	Shared Neighborhood Hits	22
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

CO039_MOUSE
θ value	5.27518 (rank : 198)	NC score	0.040544 (rank : 146)
Query Neighborhood Hits	274	Target Neighborhood Hits	445	Shared Neighborhood Hits	77
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

DAB1_HUMAN
θ value	5.27518 (rank : 199)	NC score	0.022688 (rank : 204)
Query Neighborhood Hits	274	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

DACT1_MOUSE
θ value	5.27518 (rank : 200)	NC score	0.023933 (rank : 199)
Query Neighborhood Hits	274	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

ENAH_MOUSE
θ value	5.27518 (rank : 201)	NC score	0.040834 (rank : 145)
Query Neighborhood Hits	274	Target Neighborhood Hits	919	Shared Neighborhood Hits	90
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

FOXB2_MOUSE
θ value	5.27518 (rank : 202)	NC score	0.010203 (rank : 284)
Query Neighborhood Hits	274	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

FOXC1_MOUSE
θ value	5.27518 (rank : 203)	NC score	0.013578 (rank : 262)
Query Neighborhood Hits	274	Target Neighborhood Hits	218	Shared Neighborhood Hits	31
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

GSCR1_HUMAN
θ value	5.27518 (rank : 204)	NC score	0.057317 (rank : 89)
Query Neighborhood Hits	274	Target Neighborhood Hits	674	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

HCN2_HUMAN
θ value	5.27518 (rank : 205)	NC score	0.027019 (rank : 183)
Query Neighborhood Hits	274	Target Neighborhood Hits	369	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HIPK3_MOUSE
θ value	5.27518 (rank : 206)	NC score	0.000095 (rank : 329)
Query Neighborhood Hits	274	Target Neighborhood Hits	857	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

HXA3_HUMAN
θ value	5.27518 (rank : 207)	NC score	0.018482 (rank : 237)
Query Neighborhood Hits	274	Target Neighborhood Hits	535	Shared Neighborhood Hits	54
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

IASPP_HUMAN
θ value	5.27518 (rank : 208)	NC score	0.027870 (rank : 178)
Query Neighborhood Hits	274	Target Neighborhood Hits	688	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

LDB3_MOUSE
θ value	5.27518 (rank : 209)	NC score	0.017605 (rank : 243)
Query Neighborhood Hits	274	Target Neighborhood Hits	510	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

NALDL_HUMAN
θ value	5.27518 (rank : 210)	NC score	0.010795 (rank : 280)
Query Neighborhood Hits	274	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQQ1, O43176	Gene names	NAALADL1, NAALADASEL, NAALADL
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).

RAD50_HUMAN
θ value	5.27518 (rank : 211)	NC score	0.007379 (rank : 302)
Query Neighborhood Hits	274	Target Neighborhood Hits	1317	Shared Neighborhood Hits	37
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RIN1_HUMAN
θ value	5.27518 (rank : 212)	NC score	0.009571 (rank : 289)
Query Neighborhood Hits	274	Target Neighborhood Hits	52	Shared Neighborhood Hits	8
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

SEM3F_HUMAN
θ value	5.27518 (rank : 213)	NC score	0.001787 (rank : 325)
Query Neighborhood Hits	274	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

SEN34_MOUSE
θ value	5.27518 (rank : 214)	NC score	0.015374 (rank : 253)
Query Neighborhood Hits	274	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

SOX13_HUMAN
θ value	5.27518 (rank : 215)	NC score	0.019412 (rank : 231)
Query Neighborhood Hits	274	Target Neighborhood Hits	464	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

SRRM1_MOUSE
θ value	5.27518 (rank : 216)	NC score	0.066920 (rank : 60)
Query Neighborhood Hits	274	Target Neighborhood Hits	966	Shared Neighborhood Hits	111
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TAF4_HUMAN
θ value	5.27518 (rank : 217)	NC score	0.055020 (rank : 94)
Query Neighborhood Hits	274	Target Neighborhood Hits	687	Shared Neighborhood Hits	90
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

AKAP2_MOUSE
θ value	6.88961 (rank : 218)	NC score	0.029516 (rank : 176)
Query Neighborhood Hits	274	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANKS6_MOUSE
θ value	6.88961 (rank : 219)	NC score	0.012741 (rank : 270)
Query Neighborhood Hits	274	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

BRD4_MOUSE
θ value	6.88961 (rank : 220)	NC score	0.035174 (rank : 157)
Query Neighborhood Hits	274	Target Neighborhood Hits	845	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CPSM_HUMAN
θ value	6.88961 (rank : 221)	NC score	0.006285 (rank : 310)
Query Neighborhood Hits	274	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P31327, O43774, Q7Z5I5	Gene names	CPS1
Domain Architecture
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

EMIL2_HUMAN
θ value	6.88961 (rank : 222)	NC score	0.011836 (rank : 274)
Query Neighborhood Hits	274	Target Neighborhood Hits	573	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

EMSY_MOUSE
θ value	6.88961 (rank : 223)	NC score	0.023186 (rank : 200)
Query Neighborhood Hits	274	Target Neighborhood Hits	294	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

FOSB_HUMAN
θ value	6.88961 (rank : 224)	NC score	0.019606 (rank : 229)
Query Neighborhood Hits	274	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

FYV1_MOUSE
θ value	6.88961 (rank : 225)	NC score	0.013999 (rank : 261)
Query Neighborhood Hits	274	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

GSH2_MOUSE
θ value	6.88961 (rank : 226)	NC score	0.008115 (rank : 297)
Query Neighborhood Hits	274	Target Neighborhood Hits	319	Shared Neighborhood Hits	14
SwissProt Accessions	P31316	Gene names	Gsh2, Gsh-2
Domain Architecture
Description	Homeobox protein GSH-2.

HCN4_HUMAN
θ value	6.88961 (rank : 227)	NC score	0.022343 (rank : 208)
Query Neighborhood Hits	274	Target Neighborhood Hits	303	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

JADE2_MOUSE
θ value	6.88961 (rank : 228)	NC score	0.026278 (rank : 188)
Query Neighborhood Hits	274	Target Neighborhood Hits	560	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

K0157_HUMAN
θ value	6.88961 (rank : 229)	NC score	0.011397 (rank : 276)
Query Neighborhood Hits	274	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

MEF2D_MOUSE
θ value	6.88961 (rank : 230)	NC score	0.012778 (rank : 268)
Query Neighborhood Hits	274	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

PAWR_HUMAN
θ value	6.88961 (rank : 231)	NC score	0.025765 (rank : 191)
Query Neighborhood Hits	274	Target Neighborhood Hits	252	Shared Neighborhood Hits	14
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

PHLA1_HUMAN
θ value	6.88961 (rank : 232)	NC score	0.026147 (rank : 189)
Query Neighborhood Hits	274	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

RP1L1_HUMAN
θ value	6.88961 (rank : 233)	NC score	0.042034 (rank : 139)
Query Neighborhood Hits	274	Target Neighborhood Hits	1072	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SAHH3_HUMAN
θ value	6.88961 (rank : 234)	NC score	0.010417 (rank : 283)
Query Neighborhood Hits	274	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH3_MOUSE
θ value	6.88961 (rank : 235)	NC score	0.010421 (rank : 282)
Query Neighborhood Hits	274	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SIAH2_MOUSE
θ value	6.88961 (rank : 236)	NC score	0.007661 (rank : 299)
Query Neighborhood Hits	274	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

SYTL1_MOUSE
θ value	6.88961 (rank : 237)	NC score	0.010464 (rank : 281)
Query Neighborhood Hits	274	Target Neighborhood Hits	314	Shared Neighborhood Hits	22
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TBC12_HUMAN
θ value	6.88961 (rank : 238)	NC score	0.005305 (rank : 315)
Query Neighborhood Hits	274	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TM108_HUMAN
θ value	6.88961 (rank : 239)	NC score	0.022639 (rank : 205)
Query Neighborhood Hits	274	Target Neighborhood Hits	166	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

ZEP1_HUMAN
θ value	6.88961 (rank : 240)	NC score	0.011239 (rank : 277)
Query Neighborhood Hits	274	Target Neighborhood Hits	1036	Shared Neighborhood Hits	56
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

AFAD_HUMAN
θ value	8.99809 (rank : 241)	NC score	0.009385 (rank : 291)
Query Neighborhood Hits	274	Target Neighborhood Hits	689	Shared Neighborhood Hits	33
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ATX2_MOUSE
θ value	8.99809 (rank : 242)	NC score	0.031589 (rank : 167)
Query Neighborhood Hits	274	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

AXN2_MOUSE
θ value	8.99809 (rank : 243)	NC score	0.015300 (rank : 255)
Query Neighborhood Hits	274	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

BRD4_HUMAN
θ value	8.99809 (rank : 244)	NC score	0.032774 (rank : 165)
Query Neighborhood Hits	274	Target Neighborhood Hits	851	Shared Neighborhood Hits	86
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CAD15_HUMAN
θ value	8.99809 (rank : 245)	NC score	-0.001303 (rank : 330)
Query Neighborhood Hits	274	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P55291	Gene names	CDH15, CDH14, CDH3
Domain Architecture
Description	Cadherin-15 precursor (Muscle-cadherin) (M-cadherin) (Cadherin-14).

CDYL1_HUMAN
θ value	8.99809 (rank : 246)	NC score	0.003463 (rank : 319)
Query Neighborhood Hits	274	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CJ108_HUMAN
θ value	8.99809 (rank : 247)	NC score	0.049638 (rank : 129)
Query Neighborhood Hits	274	Target Neighborhood Hits	165	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

CREM_MOUSE
θ value	8.99809 (rank : 248)	NC score	0.005475 (rank : 313)
Query Neighborhood Hits	274	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

CT032_HUMAN
θ value	8.99809 (rank : 249)	NC score	0.009190 (rank : 293)
Query Neighborhood Hits	274	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

DEN1A_MOUSE
θ value	8.99809 (rank : 250)	NC score	0.011191 (rank : 278)
Query Neighborhood Hits	274	Target Neighborhood Hits	178	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DMRTC_HUMAN
θ value	8.99809 (rank : 251)	NC score	0.009211 (rank : 292)
Query Neighborhood Hits	274	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

DOT1L_HUMAN
θ value	8.99809 (rank : 252)	NC score	0.037937 (rank : 150)
Query Neighborhood Hits	274	Target Neighborhood Hits	660	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

DPOLM_HUMAN
θ value	8.99809 (rank : 253)	NC score	0.004972 (rank : 316)
Query Neighborhood Hits	274	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

FHOD1_MOUSE
θ value	8.99809 (rank : 254)	NC score	0.018153 (rank : 241)
Query Neighborhood Hits	274	Target Neighborhood Hits	217	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

FOS_MOUSE
θ value	8.99809 (rank : 255)	NC score	0.012303 (rank : 272)
Query Neighborhood Hits	274	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

FOXP4_HUMAN
θ value	8.99809 (rank : 256)	NC score	0.012893 (rank : 267)
Query Neighborhood Hits	274	Target Neighborhood Hits	246	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

GP178_HUMAN
θ value	8.99809 (rank : 257)	NC score	0.015310 (rank : 254)
Query Neighborhood Hits	274	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

GRAP1_MOUSE
θ value	8.99809 (rank : 258)	NC score	0.007099 (rank : 305)
Query Neighborhood Hits	274	Target Neighborhood Hits	1234	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HXA3_MOUSE
θ value	8.99809 (rank : 259)	NC score	0.018231 (rank : 239)
Query Neighborhood Hits	274	Target Neighborhood Hits	558	Shared Neighborhood Hits	56
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

IRF3_HUMAN
θ value	8.99809 (rank : 260)	NC score	0.006963 (rank : 308)
Query Neighborhood Hits	274	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

K1210_HUMAN
θ value	8.99809 (rank : 261)	NC score	0.026757 (rank : 184)
Query Neighborhood Hits	274	Target Neighborhood Hits	219	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

K1279_HUMAN
θ value	8.99809 (rank : 262)	NC score	0.007709 (rank : 298)
Query Neighborhood Hits	274	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EK5, Q9BR89, Q9ULE1, Q9Y428	Gene names	KIAA1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

NOTC2_MOUSE
θ value	8.99809 (rank : 263)	NC score	0.005740 (rank : 312)
Query Neighborhood Hits	274	Target Neighborhood Hits	1069	Shared Neighborhood Hits	52
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OBSCN_HUMAN
θ value	8.99809 (rank : 264)	NC score	0.007069 (rank : 306)
Query Neighborhood Hits	274	Target Neighborhood Hits	1931	Shared Neighborhood Hits	93
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PACN3_HUMAN
θ value	8.99809 (rank : 265)	NC score	0.002893 (rank : 322)
Query Neighborhood Hits	274	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

RB15B_HUMAN
θ value	8.99809 (rank : 266)	NC score	0.006493 (rank : 309)
Query Neighborhood Hits	274	Target Neighborhood Hits	251	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

RREB1_HUMAN
θ value	8.99809 (rank : 267)	NC score	0.003063 (rank : 321)
Query Neighborhood Hits	274	Target Neighborhood Hits	879	Shared Neighborhood Hits	46
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

SAMD4_HUMAN
θ value	8.99809 (rank : 268)	NC score	0.007198 (rank : 304)
Query Neighborhood Hits	274	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SRBP2_HUMAN
θ value	8.99809 (rank : 269)	NC score	0.009949 (rank : 287)
Query Neighborhood Hits	274	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

T22D4_MOUSE
θ value	8.99809 (rank : 270)	NC score	0.011174 (rank : 279)
Query Neighborhood Hits	274	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

TMPSD_HUMAN
θ value	8.99809 (rank : 271)	NC score	0.003221 (rank : 320)
Query Neighborhood Hits	274	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TRIP6_HUMAN
θ value	8.99809 (rank : 272)	NC score	0.008433 (rank : 296)
Query Neighborhood Hits	274	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

ULK1_HUMAN
θ value	8.99809 (rank : 273)	NC score	0.002196 (rank : 323)
Query Neighborhood Hits	274	Target Neighborhood Hits	1121	Shared Neighborhood Hits	53
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN696_HUMAN
θ value	8.99809 (rank : 274)	NC score	-0.004016 (rank : 331)
Query Neighborhood Hits	274	Target Neighborhood Hits	743	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H7X3	Gene names	ZNF696
Domain Architecture	No domain graphic available
Description	Zinc finger protein 696.

3BP2_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.112690 (rank : 32)
Query Neighborhood Hits	274	Target Neighborhood Hits	296	Shared Neighborhood Hits	46
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.109061 (rank : 33)
Query Neighborhood Hits	274	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

AB1IP_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.050043 (rank : 127)
Query Neighborhood Hits	274	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

ANLN_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.106033 (rank : 35)
Query Neighborhood Hits	274	Target Neighborhood Hits	222	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANLN_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.087045 (rank : 49)
Query Neighborhood Hits	274	Target Neighborhood Hits	297	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ATX1_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.053218 (rank : 106)
Query Neighborhood Hits	274	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

ATX7_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.064868 (rank : 67)
Query Neighborhood Hits	274	Target Neighborhood Hits	328	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

BAT2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.053115 (rank : 107)
Query Neighborhood Hits	274	Target Neighborhood Hits	931	Shared Neighborhood Hits	124
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BAT2_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.050948 (rank : 122)
Query Neighborhood Hits	274	Target Neighborhood Hits	947	Shared Neighborhood Hits	127
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

BCL9_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.064013 (rank : 71)
Query Neighborhood Hits	274	Target Neighborhood Hits	1008	Shared Neighborhood Hits	109
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CBP_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.058688 (rank : 84)
Query Neighborhood Hits	274	Target Neighborhood Hits	1051	Shared Neighborhood Hits	122
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CENB2_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.066384 (rank : 64)
Query Neighborhood Hits	274	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.058026 (rank : 87)
Query Neighborhood Hits	274	Target Neighborhood Hits	395	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CNKR1_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.176910 (rank : 23)
Query Neighborhood Hits	274	Target Neighborhood Hits	154	Shared Neighborhood Hits	27
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.092779 (rank : 43)
Query Neighborhood Hits	274	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.092884 (rank : 42)
Query Neighborhood Hits	274	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.096456 (rank : 39)
Query Neighborhood Hits	274	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.101515 (rank : 37)
Query Neighborhood Hits	274	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DYN2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.050587 (rank : 124)
Query Neighborhood Hits	274	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

DYN3_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.052446 (rank : 111)
Query Neighborhood Hits	274	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

FA47A_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.051395 (rank : 119)
Query Neighborhood Hits	274	Target Neighborhood Hits	451	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

GNRP_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.058348 (rank : 85)
Query Neighborhood Hits	274	Target Neighborhood Hits	239	Shared Neighborhood Hits	23
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GNRP_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.055804 (rank : 93)
Query Neighborhood Hits	274	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

GPS2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.064385 (rank : 70)
Query Neighborhood Hits	274	Target Neighborhood Hits	459	Shared Neighborhood Hits	49
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

K1543_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.052788 (rank : 109)
Query Neighborhood Hits	274	Target Neighborhood Hits	435	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MAGE1_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.056548 (rank : 91)
Query Neighborhood Hits	274	Target Neighborhood Hits	1389	Shared Neighborhood Hits	139
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MUC1_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.077624 (rank : 53)
Query Neighborhood Hits	274	Target Neighborhood Hits	975	Shared Neighborhood Hits	122
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

MUC7_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.054045 (rank : 101)
Query Neighborhood Hits	274	Target Neighborhood Hits	538	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NCOA6_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.072107 (rank : 58)
Query Neighborhood Hits	274	Target Neighborhood Hits	1202	Shared Neighborhood Hits	124
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PHLB1_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.060684 (rank : 80)
Query Neighborhood Hits	274	Target Neighborhood Hits	1038	Shared Neighborhood Hits	94
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.051692 (rank : 117)
Query Neighborhood Hits	274	Target Neighborhood Hits	678	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PKHA1_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.118828 (rank : 27)
Query Neighborhood Hits	274	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.118136 (rank : 28)
Query Neighborhood Hits	274	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.094790 (rank : 40)
Query Neighborhood Hits	274	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.107953 (rank : 34)
Query Neighborhood Hits	274	Target Neighborhood Hits	116	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.115218 (rank : 31)
Query Neighborhood Hits	274	Target Neighborhood Hits	283	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.116847 (rank : 30)
Query Neighborhood Hits	274	Target Neighborhood Hits	202	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.090739 (rank : 45)
Query Neighborhood Hits	274	Target Neighborhood Hits	455	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.133974 (rank : 24)
Query Neighborhood Hits	274	Target Neighborhood Hits	556	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.127420 (rank : 25)
Query Neighborhood Hits	274	Target Neighborhood Hits	591	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHB2_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.050522 (rank : 125)
Query Neighborhood Hits	274	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

PLEK2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.088092 (rank : 48)
Query Neighborhood Hits	274	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.089653 (rank : 46)
Query Neighborhood Hits	274	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.117563 (rank : 29)
Query Neighborhood Hits	274	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.120154 (rank : 26)
Query Neighborhood Hits	274	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PRB4S_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.052139 (rank : 115)
Query Neighborhood Hits	274	Target Neighborhood Hits	330	Shared Neighborhood Hits	56
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

PRP2_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.061696 (rank : 76)
Query Neighborhood Hits	274	Target Neighborhood Hits	347	Shared Neighborhood Hits	60
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.052685 (rank : 110)
Query Neighborhood Hits	274	Target Neighborhood Hits	460	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

PRR8_HUMAN
θ value	θ > 10 (rank : 323)	NC score	0.053266 (rank : 105)
Query Neighborhood Hits	274	Target Neighborhood Hits	217	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

RASA1_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.072115 (rank : 57)
Query Neighborhood Hits	274	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RHG25_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.069933 (rank : 59)
Query Neighborhood Hits	274	Target Neighborhood Hits	550	Shared Neighborhood Hits	30
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.072557 (rank : 56)
Query Neighborhood Hits	274	Target Neighborhood Hits	492	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SET1A_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.050174 (rank : 126)
Query Neighborhood Hits	274	Target Neighborhood Hits	690	Shared Neighborhood Hits	83
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SWP70_HUMAN
θ value	θ > 10 (rank : 328)	NC score	0.066778 (rank : 62)
Query Neighborhood Hits	274	Target Neighborhood Hits	973	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 329)	NC score	0.058833 (rank : 83)
Query Neighborhood Hits	274	Target Neighborhood Hits	1097	Shared Neighborhood Hits	44
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TARSH_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.052392 (rank : 112)
Query Neighborhood Hits	274	Target Neighborhood Hits	768	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TBCD2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.050037 (rank : 128)
Query Neighborhood Hits	274	Target Neighborhood Hits	419	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

Hits sorted by NC score

IQEC3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	274	Target Neighborhood Hits	274	Shared Neighborhood Hits	274
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_HUMAN
NC score	0.968732 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	274	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC1_MOUSE
NC score	0.952424 (rank : 3)	θ value	6.83811e-141 (rank : 4)
Query Neighborhood Hits	274	Target Neighborhood Hits	54	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC1_HUMAN
NC score	0.951828 (rank : 4)	θ value	1.19867e-161 (rank : 3)
Query Neighborhood Hits	274	Target Neighborhood Hits	76	Shared Neighborhood Hits	26
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC2_HUMAN
NC score	0.916929 (rank : 5)	θ value	3.76091e-131 (rank : 5)
Query Neighborhood Hits	274	Target Neighborhood Hits	403	Shared Neighborhood Hits	68
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
NC score	0.916052 (rank : 6)	θ value	1.09426e-130 (rank : 6)
Query Neighborhood Hits	274	Target Neighborhood Hits	417	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

GBF1_HUMAN
NC score	0.819649 (rank : 7)	θ value	1.85889e-29 (rank : 17)
Query Neighborhood Hits	274	Target Neighborhood Hits	142	Shared Neighborhood Hits	45
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

BIG1_HUMAN
NC score	0.814410 (rank : 8)	θ value	3.4976e-36 (rank : 13)
Query Neighborhood Hits	274	Target Neighborhood Hits	76	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CYH2_MOUSE
NC score	0.800378 (rank : 9)	θ value	4.41421e-39 (rank : 8)
Query Neighborhood Hits	274	Target Neighborhood Hits	171	Shared Neighborhood Hits	27
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.800094 (rank : 10)	θ value	3.37985e-39 (rank : 7)
Query Neighborhood Hits	274	Target Neighborhood Hits	175	Shared Neighborhood Hits	28
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

BIG2_HUMAN
NC score	0.797991 (rank : 11)	θ value	4.42448e-31 (rank : 16)
Query Neighborhood Hits	274	Target Neighborhood Hits	66	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

CYH3_HUMAN
NC score	0.796078 (rank : 12)	θ value	2.86122e-38 (rank : 10)
Query Neighborhood Hits	274	Target Neighborhood Hits	137	Shared Neighborhood Hits	28
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_MOUSE
NC score	0.793022 (rank : 13)	θ value	1.6774e-38 (rank : 9)
Query Neighborhood Hits	274	Target Neighborhood Hits	176	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH3_MOUSE
NC score	0.790930 (rank : 14)	θ value	4.88048e-38 (rank : 12)
Query Neighborhood Hits	274	Target Neighborhood Hits	148	Shared Neighborhood Hits	28
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

CYH4_MOUSE
NC score	0.790897 (rank : 15)	θ value	2.12192e-33 (rank : 14)
Query Neighborhood Hits	274	Target Neighborhood Hits	134	Shared Neighborhood Hits	28
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
NC score	0.790345 (rank : 16)	θ value	2.34606e-32 (rank : 15)
Query Neighborhood Hits	274	Target Neighborhood Hits	135	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH1_HUMAN
NC score	0.790334 (rank : 17)	θ value	3.73686e-38 (rank : 11)
Query Neighborhood Hits	274	Target Neighborhood Hits	184	Shared Neighborhood Hits	28
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

FBX8_MOUSE
NC score	0.777222 (rank : 18)	θ value	9.56915e-18 (rank : 19)
Query Neighborhood Hits	274	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX8_HUMAN
NC score	0.775906 (rank : 19)	θ value	3.28887e-18 (rank : 18)
Query Neighborhood Hits	274	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

PSD3_HUMAN
NC score	0.728360 (rank : 20)	θ value	1.63225e-17 (rank : 20)
Query Neighborhood Hits	274	Target Neighborhood Hits	75	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_MOUSE
NC score	0.697697 (rank : 21)	θ value	2.7842e-17 (rank : 22)
Query Neighborhood Hits	274	Target Neighborhood Hits	78	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD4_HUMAN
NC score	0.696952 (rank : 22)	θ value	1.63225e-17 (rank : 21)
Query Neighborhood Hits	274	Target Neighborhood Hits	178	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

CNKR1_HUMAN
NC score	0.176910 (rank : 23)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	274	Target Neighborhood Hits	154	Shared Neighborhood Hits	27
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA6_HUMAN
NC score	0.133974 (rank : 24)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	274	Target Neighborhood Hits	556	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.127420 (rank : 25)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	274	Target Neighborhood Hits	591	Shared Neighborhood Hits	50
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK_MOUSE
NC score	0.120154 (rank : 26)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	274	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PKHA1_HUMAN
NC score	0.118828 (rank : 27)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	274	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.118136 (rank : 28)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	274	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_HUMAN
NC score	0.117563 (rank : 29)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	274	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHA4_MOUSE
NC score	0.116847 (rank : 30)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	274	Target Neighborhood Hits	202	Shared Neighborhood Hits	37
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_HUMAN
NC score	0.115218 (rank : 31)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	274	Target Neighborhood Hits	283	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

3BP2_HUMAN
NC score	0.112690 (rank : 32)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	274	Target Neighborhood Hits	296	Shared Neighborhood Hits	46
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
NC score	0.109061 (rank : 33)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	274	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

PKHA2_MOUSE
NC score	0.107953 (rank : 34)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	274	Target Neighborhood Hits	116	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

ANLN_HUMAN
NC score	0.106033 (rank : 35)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	274	Target Neighborhood Hits	222	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

BASP_HUMAN
NC score	0.104429 (rank : 36)	θ value	0.00665767 (rank : 27)
Query Neighborhood Hits	274	Target Neighborhood Hits	321	Shared Neighborhood Hits	60
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DAPP1_MOUSE
NC score	0.101515 (rank : 37)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	274	Target Neighborhood Hits	225	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

BASP_MOUSE
NC score	0.100365 (rank : 38)	θ value	0.0113563 (rank : 29)
Query Neighborhood Hits	274	Target Neighborhood Hits	260	Shared Neighborhood Hits	49
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DAPP1_HUMAN
NC score	0.096456 (rank : 39)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	274	Target Neighborhood Hits	227	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA2_HUMAN
NC score	0.094790 (rank : 40)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	274	Target Neighborhood Hits	119	Shared Neighborhood Hits	16
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

OGFR_HUMAN
NC score	0.094439 (rank : 41)	θ value	0.00869519 (rank : 28)
Query Neighborhood Hits	274	Target Neighborhood Hits	1582	Shared Neighborhood Hits	159
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

CNKR2_MOUSE
NC score	0.092884 (rank : 42)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	274	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.092779 (rank : 43)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	274	Target Neighborhood Hits	197	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

BSN_MOUSE
NC score	0.092079 (rank : 44)	θ value	0.0563607 (rank : 36)
Query Neighborhood Hits	274	Target Neighborhood Hits	2057	Shared Neighborhood Hits	168
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PKHA5_HUMAN
NC score	0.090739 (rank : 45)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	274	Target Neighborhood Hits	455	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PLEK2_MOUSE
NC score	0.089653 (rank : 46)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	274	Target Neighborhood Hits	96	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PRRT3_HUMAN
NC score	0.088716 (rank : 47)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	274	Target Neighborhood Hits	998	Shared Neighborhood Hits	126
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

PLEK2_HUMAN
NC score	0.088092 (rank : 48)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	274	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

ANLN_MOUSE
NC score	0.087045 (rank : 49)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	274	Target Neighborhood Hits	297	Shared Neighborhood Hits	21
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ATX7_HUMAN
NC score	0.082464 (rank : 50)	θ value	0.0193708 (rank : 30)
Query Neighborhood Hits	274	Target Neighborhood Hits	351	Shared Neighborhood Hits	65
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

RGS3_MOUSE
NC score	0.077994 (rank : 51)	θ value	0.00390308 (rank : 26)
Query Neighborhood Hits	274	Target Neighborhood Hits	1621	Shared Neighborhood Hits	143
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

GGN_HUMAN
NC score	0.077819 (rank : 52)	θ value	1.38821 (rank : 121)
Query Neighborhood Hits	274	Target Neighborhood Hits	269	Shared Neighborhood Hits	52
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

MUC1_HUMAN
NC score	0.077624 (rank : 53)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	274	Target Neighborhood Hits	975	Shared Neighborhood Hits	122
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BSN_HUMAN
NC score	0.077444 (rank : 54)	θ value	0.163984 (rank : 45)
Query Neighborhood Hits	274	Target Neighborhood Hits	1537	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

SELPL_MOUSE
NC score	0.074449 (rank : 55)	θ value	0.0193708 (rank : 31)
Query Neighborhood Hits	274	Target Neighborhood Hits	588	Shared Neighborhood Hits	85
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

RHG25_MOUSE
NC score	0.072557 (rank : 56)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	274	Target Neighborhood Hits	492	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RASA1_HUMAN
NC score	0.072115 (rank : 57)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	274	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

NCOA6_HUMAN
NC score	0.072107 (rank : 58)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	274	Target Neighborhood Hits	1202	Shared Neighborhood Hits	124
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RHG25_HUMAN
NC score	0.069933 (rank : 59)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	274	Target Neighborhood Hits	550	Shared Neighborhood Hits	30
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SRRM1_MOUSE
NC score	0.066920 (rank : 60)	θ value	5.27518 (rank : 216)
Query Neighborhood Hits	274	Target Neighborhood Hits	966	Shared Neighborhood Hits	111
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

NACAM_MOUSE
NC score	0.066917 (rank : 61)	θ value	3.0926 (rank : 164)
Query Neighborhood Hits	274	Target Neighborhood Hits	1866	Shared Neighborhood Hits	157
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SWP70_HUMAN
NC score	0.066778 (rank : 62)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	274	Target Neighborhood Hits	973	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

PCLO_MOUSE
NC score	0.066733 (rank : 63)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	274	Target Neighborhood Hits	2275	Shared Neighborhood Hits	168
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

CENB2_HUMAN
NC score	0.066384 (rank : 64)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	274	Target Neighborhood Hits	425	Shared Neighborhood Hits	26
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

MLL3_HUMAN
NC score	0.066312 (rank : 65)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	274	Target Neighborhood Hits	1644	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PCLO_HUMAN
NC score	0.064996 (rank : 66)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	274	Target Neighborhood Hits	2046	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ATX7_MOUSE
NC score	0.064868 (rank : 67)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	274	Target Neighborhood Hits	328	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

MILK1_MOUSE
NC score	0.064860 (rank : 68)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	274	Target Neighborhood Hits	788	Shared Neighborhood Hits	103
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

RGS3_HUMAN
NC score	0.064390 (rank : 69)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	274	Target Neighborhood Hits	1375	Shared Neighborhood Hits	120
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GPS2_HUMAN
NC score	0.064385 (rank : 70)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	274	Target Neighborhood Hits	459	Shared Neighborhood Hits	49
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

BCL9_HUMAN
NC score	0.064013 (rank : 71)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	274	Target Neighborhood Hits	1008	Shared Neighborhood Hits	109
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

K1802_MOUSE
NC score	0.063873 (rank : 72)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	274	Target Neighborhood Hits	1596	Shared Neighborhood Hits	131
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CN155_HUMAN
NC score	0.063681 (rank : 73)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	274	Target Neighborhood Hits	385	Shared Neighborhood Hits	53
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

CRSP2_HUMAN
NC score	0.062984 (rank : 74)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	274	Target Neighborhood Hits	380	Shared Neighborhood Hits	63
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

NFH_MOUSE
NC score	0.062524 (rank : 75)	θ value	0.0563607 (rank : 39)
Query Neighborhood Hits	274	Target Neighborhood Hits	2247	Shared Neighborhood Hits	162
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRP2_MOUSE
NC score	0.061696 (rank : 76)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	274	Target Neighborhood Hits	347	Shared Neighborhood Hits	60
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

EP300_HUMAN
NC score	0.061618 (rank : 77)	θ value	1.06291 (rank : 104)
Query Neighborhood Hits	274	Target Neighborhood Hits	821	Shared Neighborhood Hits	96
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

GGN_MOUSE
NC score	0.061537 (rank : 78)	θ value	2.36792 (rank : 147)
Query Neighborhood Hits	274	Target Neighborhood Hits	311	Shared Neighborhood Hits	63
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SPR1B_MOUSE
NC score	0.061174 (rank : 79)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	274	Target Neighborhood Hits	395	Shared Neighborhood Hits	65
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

PHLB1_HUMAN
NC score	0.060684 (rank : 80)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	274	Target Neighborhood Hits	1038	Shared Neighborhood Hits	94
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

SON_HUMAN
NC score	0.060221 (rank : 81)	θ value	2.36792 (rank : 154)
Query Neighborhood Hits	274	Target Neighborhood Hits	1568	Shared Neighborhood Hits	141
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TCOF_HUMAN
NC score	0.059506 (rank : 82)	θ value	0.365318 (rank : 71)
Query Neighborhood Hits	274	Target Neighborhood Hits	543	Shared Neighborhood Hits	64
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SWP70_MOUSE
NC score	0.058833 (rank : 83)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	274	Target Neighborhood Hits	1097	Shared Neighborhood Hits	44
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CBP_MOUSE
NC score	0.058688 (rank : 84)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	274	Target Neighborhood Hits	1051	Shared Neighborhood Hits	122
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GNRP_HUMAN
NC score	0.058348 (rank : 85)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	274	Target Neighborhood Hits	239	Shared Neighborhood Hits	23
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

MKL1_MOUSE
NC score	0.058211 (rank : 86)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	274	Target Neighborhood Hits	667	Shared Neighborhood Hits	82
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

CENB5_HUMAN
NC score	0.058026 (rank : 87)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	274	Target Neighborhood Hits	395	Shared Neighborhood Hits	22
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

ZN207_HUMAN
NC score	0.057471 (rank : 88)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	274	Target Neighborhood Hits	326	Shared Neighborhood Hits	34
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

GSCR1_HUMAN
NC score	0.057317 (rank : 89)	θ value	5.27518 (rank : 204)
Query Neighborhood Hits	274	Target Neighborhood Hits	674	Shared Neighborhood Hits	93
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

SAPS1_HUMAN
NC score	0.056791 (rank : 90)	θ value	0.0431538 (rank : 35)
Query Neighborhood Hits	274	Target Neighborhood Hits	704	Shared Neighborhood Hits	96
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

MAGE1_HUMAN
NC score	0.056548 (rank : 91)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	274	Target Neighborhood Hits	1389	Shared Neighborhood Hits	139
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

FA47B_HUMAN
NC score	0.056478 (rank : 92)	θ value	2.36792 (rank : 146)
Query Neighborhood Hits	274	Target Neighborhood Hits	431	Shared Neighborhood Hits	63
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GNRP_MOUSE
NC score	0.055804 (rank : 93)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	274	Target Neighborhood Hits	191	Shared Neighborhood Hits	17
SwissProt Accessions	P27671	Gene names	Rasgrf1, Cdc25, Grf1
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (CDC25Mm).

TAF4_HUMAN
NC score	0.055020 (rank : 94)	θ value	5.27518 (rank : 217)
Query Neighborhood Hits	274	Target Neighborhood Hits	687	Shared Neighborhood Hits	90
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CAC1G_HUMAN
NC score	0.054853 (rank : 95)	θ value	0.000461057 (rank : 25)
Query Neighborhood Hits	274	Target Neighborhood Hits	587	Shared Neighborhood Hits	71
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

GRIN1_HUMAN
NC score	0.054686 (rank : 96)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	274	Target Neighborhood Hits	681	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

FARP1_HUMAN
NC score	0.054579 (rank : 97)	θ value	0.163984 (rank : 46)
Query Neighborhood Hits	274	Target Neighborhood Hits	241	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

PSL1_HUMAN
NC score	0.054517 (rank : 98)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	274	Target Neighborhood Hits	650	Shared Neighborhood Hits	86
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RERE_MOUSE
NC score	0.054269 (rank : 99)	θ value	0.125558 (rank : 44)
Query Neighborhood Hits	274	Target Neighborhood Hits	785	Shared Neighborhood Hits	95
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CI079_HUMAN
NC score	0.054260 (rank : 100)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	274	Target Neighborhood Hits	288	Shared Neighborhood Hits	49
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

MUC7_HUMAN
NC score	0.054045 (rank : 101)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	274	Target Neighborhood Hits	538	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

TP53B_MOUSE
NC score	0.053879 (rank : 102)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	274	Target Neighborhood Hits	644	Shared Neighborhood Hits	64
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

ATX2L_HUMAN
NC score	0.053619 (rank : 103)	θ value	2.36792 (rank : 143)
Query Neighborhood Hits	274	Target Neighborhood Hits	443	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

NRX2B_HUMAN
NC score	0.053480 (rank : 104)	θ value	0.279714 (rank : 64)
Query Neighborhood Hits	274	Target Neighborhood Hits	481	Shared Neighborhood Hits	62
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

PRR8_HUMAN
NC score	0.053266 (rank : 105)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	274	Target Neighborhood Hits	217	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NSV0	Gene names	PRR8
Domain Architecture	No domain graphic available
Description	Proline-rich protein 8.

ATX1_MOUSE
NC score	0.053218 (rank : 106)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	274	Target Neighborhood Hits	264	Shared Neighborhood Hits	46
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

BAT2_HUMAN
NC score	0.053115 (rank : 107)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	274	Target Neighborhood Hits	931	Shared Neighborhood Hits	124
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FGD4_HUMAN
NC score	0.052798 (rank : 108)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	274	Target Neighborhood Hits	219	Shared Neighborhood Hits	24
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

K1543_HUMAN
NC score	0.052788 (rank : 109)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	274	Target Neighborhood Hits	435	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PRR12_HUMAN
NC score	0.052685 (rank : 110)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	274	Target Neighborhood Hits	460	Shared Neighborhood Hits	72
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

DYN3_HUMAN
NC score	0.052446 (rank : 111)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	274	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UQ16, O14982, O95555, Q5W129, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6	Gene names	DNM3, KIAA0820
Domain Architecture
Description	Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin).

TARSH_HUMAN
NC score	0.052392 (rank : 112)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	274	Target Neighborhood Hits	768	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

SRRM2_MOUSE
NC score	0.052376 (rank : 113)	θ value	1.81305 (rank : 138)
Query Neighborhood Hits	274	Target Neighborhood Hits	1470	Shared Neighborhood Hits	123
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

K1802_HUMAN
NC score	0.052301 (rank : 114)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	274	Target Neighborhood Hits	1378	Shared Neighborhood Hits	115
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PRB4S_HUMAN
NC score	0.052139 (rank : 115)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	274	Target Neighborhood Hits	330	Shared Neighborhood Hits	56
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

FGD4_MOUSE
NC score	0.051695 (rank : 116)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	274	Target Neighborhood Hits	227	Shared Neighborhood Hits	24
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

PHLB1_MOUSE
NC score	0.051692 (rank : 117)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	274	Target Neighborhood Hits	678	Shared Neighborhood Hits	71
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

ZN750_MOUSE
NC score	0.051429 (rank : 118)	θ value	0.0961366 (rank : 42)
Query Neighborhood Hits	274	Target Neighborhood Hits	346	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BH05, Q66JP3, Q8C0L1	Gene names	Znf750
Domain Architecture	No domain graphic available
Description	Protein ZNF750.

FA47A_HUMAN
NC score	0.051395 (rank : 119)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	274	Target Neighborhood Hits	451	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

FGD6_HUMAN
NC score	0.051236 (rank : 120)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	274	Target Neighborhood Hits	237	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZV73, Q6ZR53, Q7Z2Z7, Q96D44, Q9NUR8, Q9P2I5	Gene names	FGD6, KIAA1362, ZFYVE24
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24).

FGD6_MOUSE
NC score	0.051220 (rank : 121)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	274	Target Neighborhood Hits	282	Shared Neighborhood Hits	33
SwissProt Accessions	Q69ZL1, Q8C8W5, Q8K3B0, Q9D3Y7	Gene names	Fgd6, Kiaa1362
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 6.

BAT2_MOUSE
NC score	0.050948 (rank : 122)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	274	Target Neighborhood Hits	947	Shared Neighborhood Hits	127
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

GRIN1_MOUSE
NC score	0.050874 (rank : 123)	θ value	1.38821 (rank : 122)
Query Neighborhood Hits	274	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

DYN2_HUMAN
NC score	0.050587 (rank : 124)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	274	Target Neighborhood Hits	112	Shared Neighborhood Hits	22
SwissProt Accessions	P50570, Q7Z5S3, Q9UPH4	Gene names	DNM2, DYN2
Domain Architecture
Description	Dynamin-2 (EC 3.6.5.5).

PKHB2_HUMAN
NC score	0.050522 (rank : 125)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	274	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

SET1A_HUMAN
NC score	0.050174 (rank : 126)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	274	Target Neighborhood Hits	690	Shared Neighborhood Hits	83
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AB1IP_HUMAN
NC score	0.050043 (rank : 127)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	274	Target Neighborhood Hits	213	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z5R6, Q8IWS8, Q8IZZ7	Gene names	APBB1IP, PREL1, RARP1, RIAM
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Rap1-GTP- interacting adapter molecule) (RIAM) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Retinoic acid-responsive proline- rich protein 1) (RARP-1).

TBCD2_HUMAN
NC score	0.050037 (rank : 128)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	274	Target Neighborhood Hits	419	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

CJ108_HUMAN
NC score	0.049638 (rank : 129)	θ value	8.99809 (rank : 247)
Query Neighborhood Hits	274	Target Neighborhood Hits	165	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N8Z3	Gene names	C10orf108
Domain Architecture	No domain graphic available
Description	Putative uncharacterized protein C10orf108.

IWS1_MOUSE
NC score	0.049619 (rank : 130)	θ value	0.0563607 (rank : 37)
Query Neighborhood Hits	274	Target Neighborhood Hits	1258	Shared Neighborhood Hits	85
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TGON2_HUMAN
NC score	0.049482 (rank : 131)	θ value	0.365318 (rank : 72)
Query Neighborhood Hits	274	Target Neighborhood Hits	1037	Shared Neighborhood Hits	89
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

SMOO_HUMAN
NC score	0.048430 (rank : 132)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	274	Target Neighborhood Hits	391	Shared Neighborhood Hits	65
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

MLL2_HUMAN
NC score	0.048420 (rank : 133)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	274	Target Neighborhood Hits	1788	Shared Neighborhood Hits	130
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

IWS1_HUMAN
NC score	0.047254 (rank : 134)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	274	Target Neighborhood Hits	1241	Shared Neighborhood Hits	78
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SC24C_HUMAN
NC score	0.046749 (rank : 135)	θ value	1.38821 (rank : 124)
Query Neighborhood Hits	274	Target Neighborhood Hits	662	Shared Neighborhood Hits	91
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SFPQ_HUMAN
NC score	0.045797 (rank : 136)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	274	Target Neighborhood Hits	986	Shared Neighborhood Hits	83
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

IER5_MOUSE
NC score	0.045090 (rank : 137)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	274	Target Neighborhood Hits	110	Shared Neighborhood Hits	23
SwissProt Accessions	O89113, Q8CGI0	Gene names	Ier5
Domain Architecture	No domain graphic available
Description	Immediate early response gene 5 protein.

CIC_HUMAN
NC score	0.043477 (rank : 138)	θ value	2.36792 (rank : 144)
Query Neighborhood Hits	274	Target Neighborhood Hits	992	Shared Neighborhood Hits	115
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

RP1L1_HUMAN
NC score	0.042034 (rank : 139)	θ value	6.88961 (rank : 233)
Query Neighborhood Hits	274	Target Neighborhood Hits	1072	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

MNT_HUMAN
NC score	0.041949 (rank : 140)	θ value	1.38821 (rank : 123)
Query Neighborhood Hits	274	Target Neighborhood Hits	496	Shared Neighborhood Hits	73
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

FARP2_MOUSE
NC score	0.041826 (rank : 141)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	274	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q91VS8, Q3TAP2, Q69ZZ0	Gene names	Farp2, Kiaa0793
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 2 (FERM domain including RhoGEF) (FIR).

HGS_MOUSE
NC score	0.041334 (rank : 142)	θ value	0.163984 (rank : 47)
Query Neighborhood Hits	274	Target Neighborhood Hits	589	Shared Neighborhood Hits	62
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

PCQAP_HUMAN
NC score	0.041311 (rank : 143)	θ value	1.81305 (rank : 135)
Query Neighborhood Hits	274	Target Neighborhood Hits	549	Shared Neighborhood Hits	59
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

FMN1B_MOUSE
NC score	0.041297 (rank : 144)	θ value	0.125558 (rank : 43)
Query Neighborhood Hits	274	Target Neighborhood Hits	447	Shared Neighborhood Hits	65
SwissProt Accessions	Q05859	Gene names	Fmn, Ld
Domain Architecture
Description	Formin-1 isoform IV (Limb deformity protein).

ENAH_MOUSE
NC score	0.040834 (rank : 145)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	274	Target Neighborhood Hits	919	Shared Neighborhood Hits	90
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

CO039_MOUSE
NC score	0.040544 (rank : 146)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	274	Target Neighborhood Hits	445	Shared Neighborhood Hits	77
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

MBB1A_HUMAN
NC score	0.039568 (rank : 147)	θ value	1.81305 (rank : 132)
Query Neighborhood Hits	274	Target Neighborhood Hits	665	Shared Neighborhood Hits	72
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

DACT1_HUMAN
NC score	0.038829 (rank : 148)	θ value	1.81305 (rank : 129)
Query Neighborhood Hits	274	Target Neighborhood Hits	228	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NYF0, Q86TY0	Gene names	DACT1, DPR1, HNG3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (hDPR1) (Heptacellular carcinoma novel gene 3 protein).

ARI1A_HUMAN
NC score	0.038139 (rank : 149)	θ value	2.36792 (rank : 142)
Query Neighborhood Hits	274	Target Neighborhood Hits	787	Shared Neighborhood Hits	82
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

DOT1L_HUMAN
NC score	0.037937 (rank : 150)	θ value	8.99809 (rank : 252)
Query Neighborhood Hits	274	Target Neighborhood Hits	660	Shared Neighborhood Hits	72
SwissProt Accessions	Q8TEK3, O60379, Q96JL1	Gene names	DOT1L, KIAA1814
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.43) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (DOT1-like protein).

PI5PA_MOUSE
NC score	0.037747 (rank : 151)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	274	Target Neighborhood Hits	331	Shared Neighborhood Hits	59
SwissProt Accessions	P59644	Gene names	Pib5pa
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

CTDP1_HUMAN
NC score	0.037084 (rank : 152)	θ value	3.0926 (rank : 161)
Query Neighborhood Hits	274	Target Neighborhood Hits	416	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y5B0, Q7Z644, Q96BZ1, Q9Y6F5	Gene names	CTDP1, FCP1
Domain Architecture
Description	RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (TFIIF-associating CTD phosphatase).

NRX2A_HUMAN
NC score	0.036304 (rank : 153)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	274	Target Neighborhood Hits	614	Shared Neighborhood Hits	64
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PHC2_HUMAN
NC score	0.035921 (rank : 154)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	274	Target Neighborhood Hits	388	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IXK0, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306, Q8TAG8, Q96BL4, Q9Y4Y7	Gene names	PHC2, EDR2, PH2
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 2 (hPH2) (Early development regulatory protein 2).

MILK2_HUMAN
NC score	0.035549 (rank : 155)	θ value	3.0926 (rank : 163)
Query Neighborhood Hits	274	Target Neighborhood Hits	457	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

IMMT_MOUSE
NC score	0.035315 (rank : 156)	θ value	0.365318 (rank : 68)
Query Neighborhood Hits	274	Target Neighborhood Hits	326	Shared Neighborhood Hits	18
SwissProt Accessions	Q8CAQ8, Q66JS4, Q7TNE2, Q8C7V1, Q8CCI0, Q8CDA8, Q9D9F6	Gene names	Immt
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin).

BRD4_MOUSE
NC score	0.035174 (rank : 157)	θ value	6.88961 (rank : 220)
Query Neighborhood Hits	274	Target Neighborhood Hits	845	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CSKI1_MOUSE
NC score	0.034898 (rank : 158)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	274	Target Neighborhood Hits	1031	Shared Neighborhood Hits	102
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

RIMB1_HUMAN
NC score	0.034593 (rank : 159)	θ value	2.36792 (rank : 151)
Query Neighborhood Hits	274	Target Neighborhood Hits	1479	Shared Neighborhood Hits	96
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SEPT9_HUMAN
NC score	0.034393 (rank : 160)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	274	Target Neighborhood Hits	706	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ERCC5_MOUSE
NC score	0.034276 (rank : 161)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	274	Target Neighborhood Hits	206	Shared Neighborhood Hits	22
SwissProt Accessions	P35689, Q61528, Q64248	Gene names	Ercc5, Ercc-5, Xpg
Domain Architecture
Description	DNA-repair protein complementing XP-G cells homolog (Xeroderma pigmentosum group G-complementing protein homolog) (DNA excision repair protein ERCC-5).

NSMA2_MOUSE
NC score	0.034121 (rank : 162)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	274	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JJY3, Q3UTQ5	Gene names	smpd3
Domain Architecture	No domain graphic available
Description	Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (Neutral sphingomyelinase II) (nSMase2) (nSMase- 2).

HGS_HUMAN
NC score	0.033715 (rank : 163)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	274	Target Neighborhood Hits	517	Shared Neighborhood Hits	47
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

PTN23_HUMAN
NC score	0.033095 (rank : 164)	θ value	0.62314 (rank : 90)
Query Neighborhood Hits	274	Target Neighborhood Hits	646	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

BRD4_HUMAN
NC score	0.032774 (rank : 165)	θ value	8.99809 (rank : 244)
Query Neighborhood Hits	274	Target Neighborhood Hits	851	Shared Neighborhood Hits	86
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

AKA12_HUMAN
NC score	0.032522 (rank : 166)	θ value	2.36792 (rank : 139)
Query Neighborhood Hits	274	Target Neighborhood Hits	825	Shared Neighborhood Hits	51
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ATX2_MOUSE
NC score	0.031589 (rank : 167)	θ value	8.99809 (rank : 242)
Query Neighborhood Hits	274	Target Neighborhood Hits	445	Shared Neighborhood Hits	64
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

RANB9_HUMAN
NC score	0.031410 (rank : 168)	θ value	2.36792 (rank : 150)
Query Neighborhood Hits	274	Target Neighborhood Hits	179	Shared Neighborhood Hits	41
SwissProt Accessions	Q96S59, O94764, Q6P3T7, Q7LBR2, Q7Z7F9	Gene names	RANBP9, RANBPM
Domain Architecture	No domain graphic available
Description	Ran-binding protein 9 (RanBP9) (RanBP7) (Ran-binding protein M) (RanBPM) (BPM90) (BPM-L).

HSF2_MOUSE
NC score	0.031203 (rank : 169)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	274	Target Neighborhood Hits	153	Shared Neighborhood Hits	9
SwissProt Accessions	P38533, Q64157, Q8VEJ0, Q9Z2L8	Gene names	Hsf2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

IMMT_HUMAN
NC score	0.031031 (rank : 170)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	274	Target Neighborhood Hits	494	Shared Neighborhood Hits	27
SwissProt Accessions	Q16891, Q14539, Q15092, Q68D41, Q69HW5, Q6IBL0, Q7Z3X1, Q8TAJ5, Q9P0V2	Gene names	IMMT, HMP, PIG4
Domain Architecture	No domain graphic available
Description	Mitochondrial inner membrane protein (Mitofilin) (p87/89) (Proliferation-inducing gene 4 protein).

HSF2_HUMAN
NC score	0.030826 (rank : 171)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	274	Target Neighborhood Hits	149	Shared Neighborhood Hits	8
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

PTN23_MOUSE
NC score	0.030704 (rank : 172)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	274	Target Neighborhood Hits	726	Shared Neighborhood Hits	85
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CI082_MOUSE
NC score	0.030511 (rank : 173)	θ value	3.0926 (rank : 160)
Query Neighborhood Hits	274	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VDY9	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82 homolog.

RP3A_MOUSE
NC score	0.029669 (rank : 174)	θ value	2.36792 (rank : 152)
Query Neighborhood Hits	274	Target Neighborhood Hits	510	Shared Neighborhood Hits	70
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

CSKI1_HUMAN
NC score	0.029536 (rank : 175)	θ value	1.81305 (rank : 126)
Query Neighborhood Hits	274	Target Neighborhood Hits	997	Shared Neighborhood Hits	93
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

AKAP2_MOUSE
NC score	0.029516 (rank : 176)	θ value	6.88961 (rank : 218)
Query Neighborhood Hits	274	Target Neighborhood Hits	385	Shared Neighborhood Hits	44
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CLIC6_HUMAN
NC score	0.028430 (rank : 177)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	274	Target Neighborhood Hits	289	Shared Neighborhood Hits	35
SwissProt Accessions	Q96NY7, Q8IX31	Gene names	CLIC6, CLIC1L
Domain Architecture	No domain graphic available
Description	Chloride intracellular channel 6.

IASPP_HUMAN
NC score	0.027870 (rank : 178)	θ value	5.27518 (rank : 208)
Query Neighborhood Hits	274	Target Neighborhood Hits	688	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TIF1G_MOUSE
NC score	0.027653 (rank : 179)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	274	Target Neighborhood Hits	498	Shared Neighborhood Hits	40
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

WNK2_HUMAN
NC score	0.027652 (rank : 180)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	274	Target Neighborhood Hits	1407	Shared Neighborhood Hits	116
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

THAP4_HUMAN
NC score	0.027231 (rank : 181)	θ value	0.62314 (rank : 92)
Query Neighborhood Hits	274	Target Neighborhood Hits	92	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WY91, Q53NU7, Q6GRN0, Q6IPJ3, Q9NW26, Q9Y325	Gene names	THAP4
Domain Architecture
Description	THAP domain-containing protein 4.

ANR11_HUMAN
NC score	0.027035 (rank : 182)	θ value	2.36792 (rank : 141)
Query Neighborhood Hits	274	Target Neighborhood Hits	1289	Shared Neighborhood Hits	85
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

HCN2_HUMAN
NC score	0.027019 (rank : 183)	θ value	5.27518 (rank : 205)
Query Neighborhood Hits	274	Target Neighborhood Hits	369	Shared Neighborhood Hits	66
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

K1210_HUMAN
NC score	0.026757 (rank : 184)	θ value	8.99809 (rank : 261)
Query Neighborhood Hits	274	Target Neighborhood Hits	219	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

TACC3_HUMAN
NC score	0.026745 (rank : 185)	θ value	2.36792 (rank : 155)
Query Neighborhood Hits	274	Target Neighborhood Hits	779	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CSKI2_MOUSE
NC score	0.026634 (rank : 186)	θ value	1.81305 (rank : 127)
Query Neighborhood Hits	274	Target Neighborhood Hits	812	Shared Neighborhood Hits	70
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

CI082_HUMAN
NC score	0.026519 (rank : 187)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	274	Target Neighborhood Hits	32	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H8G2, Q5VY32, Q6IPE6, Q96C59	Gene names	C9orf82
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf82.

JADE2_MOUSE
NC score	0.026278 (rank : 188)	θ value	6.88961 (rank : 228)
Query Neighborhood Hits	274	Target Neighborhood Hits	560	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

PHLA1_HUMAN
NC score	0.026147 (rank : 189)	θ value	6.88961 (rank : 232)
Query Neighborhood Hits	274	Target Neighborhood Hits	121	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

TNKS1_HUMAN
NC score	0.025793 (rank : 190)	θ value	0.00020696 (rank : 24)
Query Neighborhood Hits	274	Target Neighborhood Hits	477	Shared Neighborhood Hits	35
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

PAWR_HUMAN
NC score	0.025765 (rank : 191)	θ value	6.88961 (rank : 231)
Query Neighborhood Hits	274	Target Neighborhood Hits	252	Shared Neighborhood Hits	14
SwissProt Accessions	Q96IZ0, O75796, Q6FHY9, Q8N700	Gene names	PAWR, PAR4
Domain Architecture	No domain graphic available
Description	PRKC apoptosis WT1 regulator protein (Prostate apoptosis response 4 protein) (Par-4).

MEGF9_MOUSE
NC score	0.025668 (rank : 192)	θ value	1.81305 (rank : 133)
Query Neighborhood Hits	274	Target Neighborhood Hits	896	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SHAN1_HUMAN
NC score	0.025153 (rank : 193)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	274	Target Neighborhood Hits	1041	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

TIF1G_HUMAN
NC score	0.024822 (rank : 194)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	274	Target Neighborhood Hits	410	Shared Neighborhood Hits	30
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

SRBP1_MOUSE
NC score	0.024649 (rank : 195)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	274	Target Neighborhood Hits	384	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

FOSB_MOUSE
NC score	0.024356 (rank : 196)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	274	Target Neighborhood Hits	137	Shared Neighborhood Hits	12
SwissProt Accessions	P13346	Gene names	Fosb
Domain Architecture	No domain graphic available
Description	Protein fosB.

CCD96_HUMAN
NC score	0.024298 (rank : 197)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	274	Target Neighborhood Hits	595	Shared Neighborhood Hits	50
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

HCN2_MOUSE
NC score	0.023945 (rank : 198)	θ value	1.81305 (rank : 130)
Query Neighborhood Hits	274	Target Neighborhood Hits	278	Shared Neighborhood Hits	51
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

DACT1_MOUSE
NC score	0.023933 (rank : 199)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	274	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

EMSY_MOUSE
NC score	0.023186 (rank : 200)	θ value	6.88961 (rank : 223)
Query Neighborhood Hits	274	Target Neighborhood Hits	294	Shared Neighborhood Hits	38
SwissProt Accessions	Q8BMB0, Q5FWK5, Q80XU1, Q8VDW9	Gene names	Emsy
Domain Architecture
Description	Protein EMSY.

HCN4_MOUSE
NC score	0.023101 (rank : 201)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	274	Target Neighborhood Hits	284	Shared Neighborhood Hits	45
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

GMIP_HUMAN
NC score	0.022936 (rank : 202)	θ value	0.0330416 (rank : 33)
Query Neighborhood Hits	274	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHMP6_MOUSE
NC score	0.022749 (rank : 203)	θ value	1.06291 (rank : 103)
Query Neighborhood Hits	274	Target Neighborhood Hits	99	Shared Neighborhood Hits	6
SwissProt Accessions	P0C0A3	Gene names	Chmp6
Domain Architecture	No domain graphic available
Description	Charged multivesicular body protein 6 (Chromatin-modifying protein 6).

DAB1_HUMAN
NC score	0.022688 (rank : 204)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	274	Target Neighborhood Hits	219	Shared Neighborhood Hits	36
SwissProt Accessions	O75553, Q9NYA8	Gene names	DAB1
Domain Architecture
Description	Disabled homolog 1.

TM108_HUMAN
NC score	0.022639 (rank : 205)	θ value	6.88961 (rank : 239)
Query Neighborhood Hits	274	Target Neighborhood Hits	166	Shared Neighborhood Hits	30
SwissProt Accessions	Q6UXF1, Q9BQH1, Q9BW81, Q9C0H3	Gene names	TMEM108, KIAA1690
Domain Architecture	No domain graphic available
Description	Transmembrane protein 108 precursor.

THAP4_MOUSE
NC score	0.022516 (rank : 206)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	274	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P3Z3, Q3US28, Q6NZN6, Q6PEN6, Q91WR2, Q9CVE5, Q9CVG3	Gene names	Thap4
Domain Architecture	No domain graphic available
Description	THAP domain-containing protein 4.

RUSC2_HUMAN
NC score	0.022411 (rank : 207)	θ value	1.81305 (rank : 136)
Query Neighborhood Hits	274	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q8N2Y8, O15080, Q6P1W7	Gene names	RUSC2, KIAA0375
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 2.

HCN4_HUMAN
NC score	0.022343 (rank : 208)	θ value	6.88961 (rank : 227)
Query Neighborhood Hits	274	Target Neighborhood Hits	303	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y3Q4, Q9UMQ7	Gene names	HCN4
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4.

HXD3_HUMAN
NC score	0.022255 (rank : 209)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	274	Target Neighborhood Hits	433	Shared Neighborhood Hits	35
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

MSH3_HUMAN
NC score	0.022208 (rank : 210)	θ value	0.21417 (rank : 54)
Query Neighborhood Hits	274	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P20585, Q6PJT5, Q86UQ6, Q92867	Gene names	MSH3, DUC1, DUG
Domain Architecture
Description	DNA mismatch repair protein Msh3 (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1).

SASH1_HUMAN
NC score	0.022155 (rank : 211)	θ value	2.36792 (rank : 153)
Query Neighborhood Hits	274	Target Neighborhood Hits	292	Shared Neighborhood Hits	38
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

PHLA1_MOUSE
NC score	0.022135 (rank : 212)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	274	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

WNK4_HUMAN
NC score	0.022086 (rank : 213)	θ value	5.44631e-05 (rank : 23)
Query Neighborhood Hits	274	Target Neighborhood Hits	1043	Shared Neighborhood Hits	57
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TAF1C_MOUSE
NC score	0.021958 (rank : 214)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	274	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PDZ2, P97359, Q3U3B6, Q8BN54	Gene names	Taf1c
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor, RNA polymerase I, subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 95 kDa) (TAFI95).

HME1_MOUSE
NC score	0.021824 (rank : 215)	θ value	0.0431538 (rank : 34)
Query Neighborhood Hits	274	Target Neighborhood Hits	397	Shared Neighborhood Hits	27
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

CMGA_HUMAN
NC score	0.021740 (rank : 216)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	274	Target Neighborhood Hits	238	Shared Neighborhood Hits	22
SwissProt Accessions	P10645, Q96E84, Q96GL7, Q9BQB5	Gene names	CHGA
Domain Architecture
Description	Chromogranin A precursor (CgA) (Pituitary secretory protein I) (SP-I) [Contains: Vasostatin-1 (Vasostatin I); Vasostatin-2 (Vasostatin II); EA-92; ES-43; Pancreastatin; SS-18; WA-8; WE-14; LF-19; AL-11; GV-19; GR-44; ER-37].

PHLPP_HUMAN
NC score	0.021640 (rank : 217)	θ value	2.36792 (rank : 149)
Query Neighborhood Hits	274	Target Neighborhood Hits	604	Shared Neighborhood Hits	55
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

CBLB_MOUSE
NC score	0.020819 (rank : 218)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	274	Target Neighborhood Hits	277	Shared Neighborhood Hits	19
SwissProt Accessions	Q3TTA7	Gene names	Cblb
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b).

MEGF9_HUMAN
NC score	0.020624 (rank : 219)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	274	Target Neighborhood Hits	557	Shared Neighborhood Hits	41
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

FOXP4_MOUSE
NC score	0.020590 (rank : 220)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	274	Target Neighborhood Hits	211	Shared Neighborhood Hits	30
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

HME1_HUMAN
NC score	0.020531 (rank : 221)	θ value	0.163984 (rank : 48)
Query Neighborhood Hits	274	Target Neighborhood Hits	384	Shared Neighborhood Hits	24
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

PKD1_HUMAN
NC score	0.020458 (rank : 222)	θ value	0.21417 (rank : 55)
Query Neighborhood Hits	274	Target Neighborhood Hits	387	Shared Neighborhood Hits	10
SwissProt Accessions	P98161, Q15140, Q15141	Gene names	PKD1
Domain Architecture
Description	Polycystin-1 precursor (Autosomal dominant polycystic kidney disease protein 1).

CBLB_HUMAN
NC score	0.020322 (rank : 223)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	274	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	Q13191, Q13192, Q13193, Q3LIC0, Q8IVC5	Gene names	CBLB, RNF56
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL-B (EC 6.3.2.-) (Signal transduction protein CBL-B) (SH3-binding protein CBL-B) (Casitas B-lineage lymphoma proto-oncogene b) (RING finger protein 56).

ARHGA_HUMAN
NC score	0.020309 (rank : 224)	θ value	3.0926 (rank : 157)
Query Neighborhood Hits	274	Target Neighborhood Hits	187	Shared Neighborhood Hits	13
SwissProt Accessions	O15013, O14665, Q68D55, Q8IWD9, Q8IY77	Gene names	ARHGEF10, KIAA0294
Domain Architecture
Description	Rho guanine nucleotide exchange factor 10.

ZN395_HUMAN
NC score	0.019986 (rank : 225)	θ value	4.03905 (rank : 193)
Query Neighborhood Hits	274	Target Neighborhood Hits	64	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H8N7, Q6F6H2, Q9BY72, Q9NPB2, Q9NS57, Q9NS58, Q9NS59	Gene names	ZNF395, HDBP2, PBF
Domain Architecture	No domain graphic available
Description	Zinc finger protein 395 (Papillomavirus-binding factor) (Papillomavirus regulatory factor 1) (PRF-1) (Huntington disease gene regulatory region-binding protein 2) (HDBP-2) (HD gene regulatory region-binding protein 2) (HD-regulating factor 2) (HDRF-2).

CUTL1_MOUSE
NC score	0.019830 (rank : 226)	θ value	1.81305 (rank : 128)
Query Neighborhood Hits	274	Target Neighborhood Hits	1620	Shared Neighborhood Hits	80
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

MAST4_HUMAN
NC score	0.019807 (rank : 227)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	274	Target Neighborhood Hits	1804	Shared Neighborhood Hits	112
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

CEBPE_HUMAN
NC score	0.019717 (rank : 228)	θ value	3.0926 (rank : 159)
Query Neighborhood Hits	274	Target Neighborhood Hits	236	Shared Neighborhood Hits	25
SwissProt Accessions	Q15744, Q15745, Q8IYI2, Q99803	Gene names	CEBPE
Domain Architecture
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

FOSB_HUMAN
NC score	0.019606 (rank : 229)	θ value	6.88961 (rank : 224)
Query Neighborhood Hits	274	Target Neighborhood Hits	141	Shared Neighborhood Hits	14
SwissProt Accessions	P53539	Gene names	FOSB, G0S3
Domain Architecture	No domain graphic available
Description	Protein fosB (G0/G1 switch regulatory protein 3).

UBQL3_HUMAN
NC score	0.019497 (rank : 230)	θ value	1.38821 (rank : 125)
Query Neighborhood Hits	274	Target Neighborhood Hits	141	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H347, Q9NRE0	Gene names	UBQLN3
Domain Architecture
Description	Ubiquilin-3.

SOX13_HUMAN
NC score	0.019412 (rank : 231)	θ value	5.27518 (rank : 215)
Query Neighborhood Hits	274	Target Neighborhood Hits	464	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

MIS_HUMAN
NC score	0.019105 (rank : 232)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	274	Target Neighborhood Hits	87	Shared Neighborhood Hits	5
SwissProt Accessions	P03971, O75246	Gene names	AMH, MIF
Domain Architecture
Description	Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone) (AMH) (Muellerian-inhibiting substance).

ASPM_MOUSE
NC score	0.018990 (rank : 233)	θ value	3.0926 (rank : 158)
Query Neighborhood Hits	274	Target Neighborhood Hits	150	Shared Neighborhood Hits	17
SwissProt Accessions	Q8CJ27, O88482, Q8BJI8, Q8BKT4	Gene names	Aspm, Calmbp1, Sha1
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein homolog (Calmodulin-binding protein 1) (Spindle and hydroxyurea checkpoint abnormal protein) (Calmodulin-binding protein Sha1).

RP3A_HUMAN
NC score	0.018809 (rank : 234)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	274	Target Neighborhood Hits	305	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

FOXGA_HUMAN
NC score	0.018798 (rank : 235)	θ value	0.365318 (rank : 67)
Query Neighborhood Hits	274	Target Neighborhood Hits	132	Shared Neighborhood Hits	18
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

DYNA_HUMAN
NC score	0.018487 (rank : 236)	θ value	0.0961366 (rank : 41)
Query Neighborhood Hits	274	Target Neighborhood Hits	1194	Shared Neighborhood Hits	50
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

HXA3_HUMAN
NC score	0.018482 (rank : 237)	θ value	5.27518 (rank : 207)
Query Neighborhood Hits	274	Target Neighborhood Hits	535	Shared Neighborhood Hits	54
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

HXD3_MOUSE
NC score	0.018424 (rank : 238)	θ value	3.0926 (rank : 162)
Query Neighborhood Hits	274	Target Neighborhood Hits	435	Shared Neighborhood Hits	31
SwissProt Accessions	P09027, Q3UUD3	Gene names	Hoxd3, Hox-4.1, Hoxd-3
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4.1) (Homeobox protein MH-19).

HXA3_MOUSE
NC score	0.018231 (rank : 239)	θ value	8.99809 (rank : 259)
Query Neighborhood Hits	274	Target Neighborhood Hits	558	Shared Neighborhood Hits	56
SwissProt Accessions	P02831, Q4V9Z8, Q61197	Gene names	Hoxa3, Hox-1.5, Hoxa-3
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1.5) (MO-10).

VTNC_HUMAN
NC score	0.018176 (rank : 240)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	274	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	P04004, P01141, Q9BSH7	Gene names	VTN
Domain Architecture
Description	Vitronectin precursor (Serum-spreading factor) (S-protein) (V75) [Contains: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin B].

FHOD1_MOUSE
NC score	0.018153 (rank : 241)	θ value	8.99809 (rank : 254)
Query Neighborhood Hits	274	Target Neighborhood Hits	217	Shared Neighborhood Hits	36
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

CEBPD_HUMAN
NC score	0.017952 (rank : 242)	θ value	4.03905 (rank : 173)
Query Neighborhood Hits	274	Target Neighborhood Hits	135	Shared Neighborhood Hits	18
SwissProt Accessions	P49716, Q14937	Gene names	CEBPD
Domain Architecture
Description	CCAAT/enhancer-binding protein delta (C/EBP delta) (Nuclear factor NF- IL6-beta) (NF-IL6-beta).

LDB3_MOUSE
NC score	0.017605 (rank : 243)	θ value	5.27518 (rank : 209)
Query Neighborhood Hits	274	Target Neighborhood Hits	510	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

GMEB2_HUMAN
NC score	0.017272 (rank : 244)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	274	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

ATS13_HUMAN
NC score	0.017090 (rank : 245)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	274	Target Neighborhood Hits	238	Shared Neighborhood Hits	13
SwissProt Accessions	Q76LX8, Q6UY16, Q710F6, Q711T8, Q96L37, Q9H0G3	Gene names	ADAMTS13, C9orf8
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

SREC2_HUMAN
NC score	0.016972 (rank : 246)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	274	Target Neighborhood Hits	645	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

NGAP_HUMAN
NC score	0.016336 (rank : 247)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	274	Target Neighborhood Hits	517	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

CYTSA_HUMAN
NC score	0.016312 (rank : 248)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	274	Target Neighborhood Hits	1138	Shared Neighborhood Hits	47
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

HXA13_HUMAN
NC score	0.016196 (rank : 249)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	274	Target Neighborhood Hits	353	Shared Neighborhood Hits	21
SwissProt Accessions	P31271, O43371	Gene names	HOXA13, HOX1J
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1J).

MYO15_MOUSE
NC score	0.016185 (rank : 250)	θ value	0.365318 (rank : 69)
Query Neighborhood Hits	274	Target Neighborhood Hits	467	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

OTU7A_HUMAN
NC score	0.016010 (rank : 251)	θ value	1.81305 (rank : 134)
Query Neighborhood Hits	274	Target Neighborhood Hits	74	Shared Neighborhood Hits	12
SwissProt Accessions	Q8TE49, Q8IWK5	Gene names	OTUD7A, C15orf16, OTUD7
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 7A (EC 3.-.-.-) (Zinc finger protein Cezanne 2).

OXRP_HUMAN
NC score	0.015915 (rank : 252)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	274	Target Neighborhood Hits	544	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SEN34_MOUSE
NC score	0.015374 (rank : 253)	θ value	5.27518 (rank : 214)
Query Neighborhood Hits	274	Target Neighborhood Hits	158	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMZ5, Q58EU2, Q99LV6, Q9CYW1	Gene names	Tsen34, Leng5, Sen34
Domain Architecture	No domain graphic available
Description	tRNA-splicing endonuclease subunit Sen34 (EC 3.1.27.9) (tRNA-intron endonuclease Sen34) (Leukocyte receptor cluster member 5 homolog).

GP178_HUMAN
NC score	0.015310 (rank : 254)	θ value	8.99809 (rank : 257)
Query Neighborhood Hits	274	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9P2C4, Q5VTU1	Gene names	GPR178, KIAA1423
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR178.

AXN2_MOUSE
NC score	0.015300 (rank : 255)	θ value	8.99809 (rank : 243)
Query Neighborhood Hits	274	Target Neighborhood Hits	116	Shared Neighborhood Hits	14
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

HXA13_MOUSE
NC score	0.015075 (rank : 256)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	274	Target Neighborhood Hits	351	Shared Neighborhood Hits	20
SwissProt Accessions	Q62424	Gene names	Hoxa13, Hox-1.10
Domain Architecture
Description	Homeobox protein Hox-A13 (Hox-1.10).

CYTSA_MOUSE
NC score	0.014883 (rank : 257)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	274	Target Neighborhood Hits	1104	Shared Neighborhood Hits	32
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

ATBF1_HUMAN
NC score	0.014074 (rank : 258)	θ value	4.03905 (rank : 172)
Query Neighborhood Hits	274	Target Neighborhood Hits	1547	Shared Neighborhood Hits	88
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PTPRN_MOUSE
NC score	0.014050 (rank : 259)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	274	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

SIRT1_HUMAN
NC score	0.014025 (rank : 260)	θ value	1.81305 (rank : 137)
Query Neighborhood Hits	274	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	Q96EB6, Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0	Gene names	SIRT1, SIR2L1
Domain Architecture
Description	NAD-dependent deacetylase sirtuin-1 (EC 3.5.1.-) (hSIRT1) (hSIR2) (SIR2-like protein 1).

FYV1_MOUSE
NC score	0.013999 (rank : 261)	θ value	6.88961 (rank : 225)
Query Neighborhood Hits	274	Target Neighborhood Hits	191	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1T6	Gene names	Pip5k3, Pikfyve
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (PIP5K) (PtdIns(4)P-5- kinase) (PIKfyve) (p235).

FOXC1_MOUSE
NC score	0.013578 (rank : 262)	θ value	5.27518 (rank : 203)
Query Neighborhood Hits	274	Target Neighborhood Hits	218	Shared Neighborhood Hits	31
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

RIOK2_HUMAN
NC score	0.013545 (rank : 263)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	274	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

SH22A_MOUSE
NC score	0.013408 (rank : 264)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	274	Target Neighborhood Hits	179	Shared Neighborhood Hits	15
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

PGCB_HUMAN
NC score	0.013009 (rank : 265)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	274	Target Neighborhood Hits	478	Shared Neighborhood Hits	33
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SPEG_HUMAN
NC score	0.013006 (rank : 266)	θ value	0.163984 (rank : 52)
Query Neighborhood Hits	274	Target Neighborhood Hits	1762	Shared Neighborhood Hits	99
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

FOXP4_HUMAN
NC score	0.012893 (rank : 267)	θ value	8.99809 (rank : 256)
Query Neighborhood Hits	274	Target Neighborhood Hits	246	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IVH2, Q96E19	Gene names	FOXP4, FKHLA
Domain Architecture
Description	Forkhead box protein P4 (Fork head-related protein-like A).

MEF2D_MOUSE
NC score	0.012778 (rank : 268)	θ value	6.88961 (rank : 230)
Query Neighborhood Hits	274	Target Neighborhood Hits	146	Shared Neighborhood Hits	23
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

AN30A_HUMAN
NC score	0.012753 (rank : 269)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	274	Target Neighborhood Hits	1119	Shared Neighborhood Hits	47
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANKS6_MOUSE
NC score	0.012741 (rank : 270)	θ value	6.88961 (rank : 219)
Query Neighborhood Hits	274	Target Neighborhood Hits	435	Shared Neighborhood Hits	29
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANKS1_HUMAN
NC score	0.012710 (rank : 271)	θ value	2.36792 (rank : 140)
Query Neighborhood Hits	274	Target Neighborhood Hits	438	Shared Neighborhood Hits	17
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

FOS_MOUSE
NC score	0.012303 (rank : 272)	θ value	8.99809 (rank : 255)
Query Neighborhood Hits	274	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	P01101	Gene names	Fos
Domain Architecture
Description	Proto-oncogene protein c-fos (Cellular oncogene fos).

HMX2_MOUSE
NC score	0.012173 (rank : 273)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	274	Target Neighborhood Hits	354	Shared Neighborhood Hits	14
SwissProt Accessions	P43687, Q8R1Q2	Gene names	Hmx2, Nkx-5.2, Nkx5-2
Domain Architecture
Description	Homeobox protein HMX2 (Homeobox protein Nkx-5.2).

EMIL2_HUMAN
NC score	0.011836 (rank : 274)	θ value	6.88961 (rank : 222)
Query Neighborhood Hits	274	Target Neighborhood Hits	573	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BXX0, Q8NBH3, Q96JQ4	Gene names	EMILIN2
Domain Architecture
Description	EMILIN-2 precursor (Elastin microfibril interface-located protein 2) (Elastin microfibril interfacer 2) (Protein FOAP-10).

FOXQ1_MOUSE
NC score	0.011717 (rank : 275)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	274	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	O70220	Gene names	Foxq1, Hfh1, Hfh1l
Domain Architecture
Description	Forkhead box protein Q1 (Hepatocyte nuclear factor 3 forkhead homolog 1) (HNF-3/forkhead-like protein 1) (HFH-1) (HFH-1l).

K0157_HUMAN
NC score	0.011397 (rank : 276)	θ value	6.88961 (rank : 229)
Query Neighborhood Hits	274	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	Q15018, Q96H11	Gene names	KIAA0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

ZEP1_HUMAN
NC score	0.011239 (rank : 277)	θ value	6.88961 (rank : 240)
Query Neighborhood Hits	274	Target Neighborhood Hits	1036	Shared Neighborhood Hits	56
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

DEN1A_MOUSE
NC score	0.011191 (rank : 278)	θ value	8.99809 (rank : 250)
Query Neighborhood Hits	274	Target Neighborhood Hits	178	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

T22D4_MOUSE
NC score	0.011174 (rank : 279)	θ value	8.99809 (rank : 270)
Query Neighborhood Hits	274	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EQN3	Gene names	Tsc22d4, Tilz2
Domain Architecture
Description	TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2).

NALDL_HUMAN
NC score	0.010795 (rank : 280)	θ value	5.27518 (rank : 210)
Query Neighborhood Hits	274	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UQQ1, O43176	Gene names	NAALADL1, NAALADASEL, NAALADL
Domain Architecture
Description	N-acetylated-alpha-linked acidic dipeptidase-like protein (EC 3.4.17.21) (NAALADase L) (Ileal dipeptidylpeptidase) (100 kDa ileum brush border membrane protein) (I100).

SYTL1_MOUSE
NC score	0.010464 (rank : 281)	θ value	6.88961 (rank : 237)
Query Neighborhood Hits	274	Target Neighborhood Hits	314	Shared Neighborhood Hits	22
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

SAHH3_MOUSE
NC score	0.010421 (rank : 282)	θ value	6.88961 (rank : 235)
Query Neighborhood Hits	274	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	Q68FL4, Q8BIH1	Gene names
Domain Architecture	No domain graphic available
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

SAHH3_HUMAN
NC score	0.010417 (rank : 283)	θ value	6.88961 (rank : 234)
Query Neighborhood Hits	274	Target Neighborhood Hits	23	Shared Neighborhood Hits	6
SwissProt Accessions	Q96HN2, O94917	Gene names	KIAA0828
Domain Architecture
Description	Putative adenosylhomocysteinase 3 (EC 3.3.1.1) (S-adenosyl-L- homocysteine hydrolase 3) (AdoHcyase 3).

FOXB2_MOUSE
NC score	0.010203 (rank : 284)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	274	Target Neighborhood Hits	139	Shared Neighborhood Hits	21
SwissProt Accessions	Q64733	Gene names	Foxb2, Fkh4
Domain Architecture
Description	Forkhead box protein B2 (Transcription factor FKH-4).

SALL3_HUMAN
NC score	0.010012 (rank : 285)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	274	Target Neighborhood Hits	1066	Shared Neighborhood Hits	70
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

CK5P2_MOUSE
NC score	0.009976 (rank : 286)	θ value	2.36792 (rank : 145)
Query Neighborhood Hits	274	Target Neighborhood Hits	1151	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

SRBP2_HUMAN
NC score	0.009949 (rank : 287)	θ value	8.99809 (rank : 269)
Query Neighborhood Hits	274	Target Neighborhood Hits	133	Shared Neighborhood Hits	7
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

GCC2_MOUSE
NC score	0.009693 (rank : 288)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	274	Target Neighborhood Hits	1619	Shared Neighborhood Hits	43
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RIN1_HUMAN
NC score	0.009571 (rank : 289)	θ value	5.27518 (rank : 212)
Query Neighborhood Hits	274	Target Neighborhood Hits	52	Shared Neighborhood Hits	8
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

TBX1_HUMAN
NC score	0.009452 (rank : 290)	θ value	0.62314 (rank : 91)
Query Neighborhood Hits	274	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	O43435, O43436, Q96RJ2	Gene names	TBX1
Domain Architecture
Description	T-box transcription factor TBX1 (T-box protein 1) (Testis-specific T- box protein).

AFAD_HUMAN
NC score	0.009385 (rank : 291)	θ value	8.99809 (rank : 241)
Query Neighborhood Hits	274	Target Neighborhood Hits	689	Shared Neighborhood Hits	33
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

DMRTC_HUMAN
NC score	0.009211 (rank : 292)	θ value	8.99809 (rank : 251)
Query Neighborhood Hits	274	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q5HYR2, Q5HYR0, Q5U5K2, Q8N6L3, Q96SD3	Gene names	DMRTC1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1.

CT032_HUMAN
NC score	0.009190 (rank : 293)	θ value	8.99809 (rank : 249)
Query Neighborhood Hits	274	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NQ75, Q96K09, Q9BYL5	Gene names	HEFL, C20orf32
Domain Architecture
Description	HEF-like protein.

PTN22_MOUSE
NC score	0.009120 (rank : 294)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	274	Target Neighborhood Hits	179	Shared Neighborhood Hits	19
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

NMDE4_HUMAN
NC score	0.008562 (rank : 295)	θ value	2.36792 (rank : 148)
Query Neighborhood Hits	274	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	O15399	Gene names	GRIN2D
Domain Architecture
Description	Glutamate [NMDA] receptor subunit epsilon 4 precursor (N-methyl D- aspartate receptor subtype 2D) (NR2D) (NMDAR2D) (EB11).

TRIP6_HUMAN
NC score	0.008433 (rank : 296)	θ value	8.99809 (rank : 272)
Query Neighborhood Hits	274	Target Neighborhood Hits	228	Shared Neighborhood Hits	16
SwissProt Accessions	Q15654, O15170, O15275, Q9BTB2, Q9UNT4	Gene names	TRIP6, OIP1
Domain Architecture
Description	Thyroid receptor-interacting protein 6 (TRIP6) (OPA-interacting protein 1) (Zyxin-related protein 1) (ZRP-1).

GSH2_MOUSE
NC score	0.008115 (rank : 297)	θ value	6.88961 (rank : 226)
Query Neighborhood Hits	274	Target Neighborhood Hits	319	Shared Neighborhood Hits	14
SwissProt Accessions	P31316	Gene names	Gsh2, Gsh-2
Domain Architecture
Description	Homeobox protein GSH-2.

K1279_HUMAN
NC score	0.007709 (rank : 298)	θ value	8.99809 (rank : 262)
Query Neighborhood Hits	274	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EK5, Q9BR89, Q9ULE1, Q9Y428	Gene names	KIAA1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

SIAH2_MOUSE
NC score	0.007661 (rank : 299)	θ value	6.88961 (rank : 236)
Query Neighborhood Hits	274	Target Neighborhood Hits	101	Shared Neighborhood Hits	10
SwissProt Accessions	Q06986	Gene names	Siah2
Domain Architecture
Description	Ubiquitin ligase SIAH2 (EC 6.3.2.-) (Seven in absentia homolog 2) (Siah-2) (mSiah2).

AATK_HUMAN
NC score	0.007475 (rank : 300)	θ value	4.03905 (rank : 171)
Query Neighborhood Hits	274	Target Neighborhood Hits	1243	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ZEP2_MOUSE
NC score	0.007395 (rank : 301)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	274	Target Neighborhood Hits	964	Shared Neighborhood Hits	52
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

RAD50_HUMAN
NC score	0.007379 (rank : 302)	θ value	5.27518 (rank : 211)
Query Neighborhood Hits	274	Target Neighborhood Hits	1317	Shared Neighborhood Hits	37
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SMC2_HUMAN
NC score	0.007235 (rank : 303)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	274	Target Neighborhood Hits	1405	Shared Neighborhood Hits	45
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SAMD4_HUMAN
NC score	0.007198 (rank : 304)	θ value	8.99809 (rank : 268)
Query Neighborhood Hits	274	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

GRAP1_MOUSE
NC score	0.007099 (rank : 305)	θ value	8.99809 (rank : 258)
Query Neighborhood Hits	274	Target Neighborhood Hits	1234	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

OBSCN_HUMAN
NC score	0.007069 (rank : 306)	θ value	8.99809 (rank : 264)
Query Neighborhood Hits	274	Target Neighborhood Hits	1931	Shared Neighborhood Hits	93
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

AAK1_MOUSE
NC score	0.007033 (rank : 307)	θ value	4.03905 (rank : 170)
Query Neighborhood Hits	274	Target Neighborhood Hits	1051	Shared Neighborhood Hits	62
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

IRF3_HUMAN
NC score	0.006963 (rank : 308)	θ value	8.99809 (rank : 260)
Query Neighborhood Hits	274	Target Neighborhood Hits	129	Shared Neighborhood Hits	19
SwissProt Accessions	Q14653	Gene names	IRF3
Domain Architecture
Description	Interferon regulatory factor 3 (IRF-3).

RB15B_HUMAN
NC score	0.006493 (rank : 309)	θ value	8.99809 (rank : 266)
Query Neighborhood Hits	274	Target Neighborhood Hits	251	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NDT2, Q6QE19, Q9BV96	Gene names	RBM15B
Domain Architecture	No domain graphic available
Description	Putative RNA-binding protein 15B (RNA-binding motif protein 15B).

CPSM_HUMAN
NC score	0.006285 (rank : 310)	θ value	6.88961 (rank : 221)
Query Neighborhood Hits	274	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P31327, O43774, Q7Z5I5	Gene names	CPS1
Domain Architecture
Description	Carbamoyl-phosphate synthase [ammonia], mitochondrial precursor (EC 6.3.4.16) (Carbamoyl-phosphate synthetase I) (CPSase I).

PDLI7_MOUSE
NC score	0.006161 (rank : 311)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	274	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q3TJD7, Q80ZY6, Q810S3, Q8C1S4, Q9CRA1	Gene names	Pdlim7, Enigma
Domain Architecture	No domain graphic available
Description	PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma).

NOTC2_MOUSE
NC score	0.005740 (rank : 312)	θ value	8.99809 (rank : 263)
Query Neighborhood Hits	274	Target Neighborhood Hits	1069	Shared Neighborhood Hits	52
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CREM_MOUSE
NC score	0.005475 (rank : 313)	θ value	8.99809 (rank : 248)
Query Neighborhood Hits	274	Target Neighborhood Hits	58	Shared Neighborhood Hits	4
SwissProt Accessions	P27699, P27698	Gene names	Crem
Domain Architecture
Description	cAMP-responsive element modulator.

ABCA2_HUMAN
NC score	0.005459 (rank : 314)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	274	Target Neighborhood Hits	143	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZC7	Gene names	ABCA2, ABC2
Domain Architecture
Description	ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2).

TBC12_HUMAN
NC score	0.005305 (rank : 315)	θ value	6.88961 (rank : 238)
Query Neighborhood Hits	274	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

DPOLM_HUMAN
NC score	0.004972 (rank : 316)	θ value	8.99809 (rank : 253)
Query Neighborhood Hits	274	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

MAST2_HUMAN
NC score	0.004951 (rank : 317)	θ value	1.81305 (rank : 131)
Query Neighborhood Hits	274	Target Neighborhood Hits	1189	Shared Neighborhood Hits	53
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MYO3A_HUMAN
NC score	0.003622 (rank : 318)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	274	Target Neighborhood Hits	1033	Shared Neighborhood Hits	22
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

CDYL1_HUMAN
NC score	0.003463 (rank : 319)	θ value	8.99809 (rank : 246)
Query Neighborhood Hits	274	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

TMPSD_HUMAN
NC score	0.003221 (rank : 320)	θ value	8.99809 (rank : 271)
Query Neighborhood Hits	274	Target Neighborhood Hits	333	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

RREB1_HUMAN
NC score	0.003063 (rank : 321)	θ value	8.99809 (rank : 267)
Query Neighborhood Hits	274	Target Neighborhood Hits	879	Shared Neighborhood Hits	46
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

PACN3_HUMAN
NC score	0.002893 (rank : 322)	θ value	8.99809 (rank : 265)
Query Neighborhood Hits	274	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

ULK1_HUMAN
NC score	0.002196 (rank : 323)	θ value	8.99809 (rank : 273)
Query Neighborhood Hits	274	Target Neighborhood Hits	1121	Shared Neighborhood Hits	53
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ZN592_MOUSE
NC score	0.001866 (rank : 324)	θ value	2.36792 (rank : 156)
Query Neighborhood Hits	274	Target Neighborhood Hits	768	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

SEM3F_HUMAN
NC score	0.001787 (rank : 325)	θ value	5.27518 (rank : 213)
Query Neighborhood Hits	274	Target Neighborhood Hits	100	Shared Neighborhood Hits	3
SwissProt Accessions	Q13275, Q13274, Q13372, Q15704	Gene names	SEMA3F
Domain Architecture
Description	Semaphorin-3F precursor (Semaphorin IV) (Sema IV) (Sema III/F).

NR2E1_MOUSE
NC score	0.001455 (rank : 326)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	274	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

KLF14_HUMAN
NC score	0.001300 (rank : 327)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	274	Target Neighborhood Hits	725	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TD94	Gene names	KLF14, BTEB5
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 14 (Transcription factor BTEB5) (Basic transcription element-binding protein 5) (BTE-binding protein 5).

ZIC5_HUMAN
NC score	0.001126 (rank : 328)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	274	Target Neighborhood Hits	774	Shared Neighborhood Hits	29
SwissProt Accessions	Q96T25	Gene names	ZIC5
Domain Architecture	No domain graphic available
Description	Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5).

HIPK3_MOUSE
NC score	0.000095 (rank : 329)	θ value	5.27518 (rank : 206)
Query Neighborhood Hits	274	Target Neighborhood Hits	857	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ERH7, O88906, Q9QZR2	Gene names	Hipk3, Fist3
Domain Architecture	No domain graphic available
Description	Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Fas- interacting serine/threonine-protein kinase) (FIST) (Nuclear body- associated kinase 3) (Nbak3) (Androgen receptor-interacting nuclear protein kinase) (ANPK).

CAD15_HUMAN
NC score	-0.001303 (rank : 330)	θ value	8.99809 (rank : 245)
Query Neighborhood Hits	274	Target Neighborhood Hits	173	Shared Neighborhood Hits	4
SwissProt Accessions	P55291	Gene names	CDH15, CDH14, CDH3
Domain Architecture
Description	Cadherin-15 precursor (Muscle-cadherin) (M-cadherin) (Cadherin-14).

ZN696_HUMAN
NC score	-0.004016 (rank : 331)	θ value	8.99809 (rank : 274)
Query Neighborhood Hits	274	Target Neighborhood Hits	743	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H7X3	Gene names	ZNF696
Domain Architecture	No domain graphic available
Description	Zinc finger protein 696.