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Network neighborhood for query Sequence : IQEC1_HUMAN

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IQEC1_HUMAN
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IQEC1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	0 (rank : 2)	NC score	0.997931 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_HUMAN
θ value	0 (rank : 3)	NC score	0.946033 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	0 (rank : 4)	NC score	0.943602 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_MOUSE
θ value	1.19867e-161 (rank : 5)	NC score	0.951828 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	274	Shared Neighborhood Hits	26
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_HUMAN
θ value	1.12714e-143 (rank : 6)	NC score	0.965990 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CYH2_HUMAN
θ value	2.11701e-41 (rank : 7)	NC score	0.800901 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	175	Shared Neighborhood Hits	25
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	2.76489e-41 (rank : 8)	NC score	0.801339 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	171	Shared Neighborhood Hits	25
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH1_MOUSE
θ value	6.81017e-40 (rank : 9)	NC score	0.793483 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH1_HUMAN
θ value	1.51715e-39 (rank : 10)	NC score	0.790635 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	184	Shared Neighborhood Hits	25
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH3_HUMAN
θ value	1.98146e-39 (rank : 11)	NC score	0.795649 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH3_MOUSE
θ value	3.37985e-39 (rank : 12)	NC score	0.789642 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

BIG1_HUMAN
θ value	5.76516e-39 (rank : 13)	NC score	0.817990 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CYH4_MOUSE
θ value	1.73584e-35 (rank : 14)	NC score	0.790726 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH4_HUMAN
θ value	5.0505e-35 (rank : 15)	NC score	0.790403 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

BIG2_HUMAN
θ value	5.22648e-32 (rank : 16)	NC score	0.799381 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

GBF1_HUMAN
θ value	5.22648e-32 (rank : 17)	NC score	0.818949 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

PSD4_HUMAN
θ value	6.62687e-19 (rank : 18)	NC score	0.691223 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	8.65492e-19 (rank : 19)	NC score	0.701152 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

FBX8_MOUSE
θ value	4.29542e-18 (rank : 20)	NC score	0.781334 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX8_HUMAN
θ value	9.56915e-18 (rank : 21)	NC score	0.779223 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

PSD3_HUMAN
θ value	4.74913e-17 (rank : 22)	NC score	0.730433 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

CE025_HUMAN
θ value	0.163984 (rank : 23)	NC score	0.041533 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

HRX_HUMAN
θ value	0.279714 (rank : 24)	NC score	0.021580 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	825	Shared Neighborhood Hits	8
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

TNR11_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.019098 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

ARHGG_MOUSE
θ value	0.813845 (rank : 26)	NC score	0.030116 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

PCLO_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.009660 (rank : 79)
Query Neighborhood Hits	76	Target Neighborhood Hits	2046	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

ANKS3_MOUSE
θ value	1.38821 (rank : 28)	NC score	0.008269 (rank : 84)
Query Neighborhood Hits	76	Target Neighborhood Hits	355	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CCD41_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.008161 (rank : 85)
Query Neighborhood Hits	76	Target Neighborhood Hits	1399	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

GP124_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.017512 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	423	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

PKHA6_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.119804 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	591	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

LMNB1_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.007979 (rank : 87)
Query Neighborhood Hits	76	Target Neighborhood Hits	719	Shared Neighborhood Hits	13
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

ATF6B_MOUSE
θ value	2.36792 (rank : 33)	NC score	0.020906 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

BIN1_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.019289 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	283	Shared Neighborhood Hits	8
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

CF203_MOUSE
θ value	2.36792 (rank : 35)	NC score	0.029098 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQF4, Q3TQU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf203 homolog.

THEX1_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.024532 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IV48, Q9NSX3	Gene names	THEX1, 3'EXO, ERI1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3' end-specific exoribonuclease) (Protein 3'hExo) (HEXO).

AKAP2_MOUSE
θ value	3.0926 (rank : 37)	NC score	0.023800 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

ANR12_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.003957 (rank : 96)
Query Neighborhood Hits	76	Target Neighborhood Hits	1081	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

DDHD1_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.013167 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

HOOK2_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.009290 (rank : 80)
Query Neighborhood Hits	76	Target Neighborhood Hits	714	Shared Neighborhood Hits	15
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

CENB2_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.064559 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

FARP1_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.037910 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	241	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

IER2_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.016374 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).

K0195_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.011522 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

MLL3_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.026537 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

AMOL1_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.016588 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	435	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

AMOL1_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.022182 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

ARHGG_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.012457 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARI4A_HUMAN
θ value	5.27518 (rank : 49)	NC score	0.012231 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	434	Shared Neighborhood Hits	13
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ASPM_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.011138 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

ATN1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.008042 (rank : 86)
Query Neighborhood Hits	76	Target Neighborhood Hits	676	Shared Neighborhood Hits	10
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

CENPF_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.003260 (rank : 98)
Query Neighborhood Hits	76	Target Neighborhood Hits	1932	Shared Neighborhood Hits	27
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DPPA2_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.024008 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z7J5, Q8WVF0	Gene names	DPPA2, PESCRG1
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 2 (Pluripotent embryonic stem cell-related protein 1).

DSPP_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.006828 (rank : 90)
Query Neighborhood Hits	76	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GOSR2_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.028338 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O14653, Q96DA5, Q9BZZ4	Gene names	GOSR2, GS27
Domain Architecture
Description	Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin).

LMNB1_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.006020 (rank : 93)
Query Neighborhood Hits	76	Target Neighborhood Hits	714	Shared Neighborhood Hits	14
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

NOLC1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.008749 (rank : 82)
Query Neighborhood Hits	76	Target Neighborhood Hits	452	Shared Neighborhood Hits	9
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

POGZ_MOUSE
θ value	5.27518 (rank : 58)	NC score	-0.000721 (rank : 102)
Query Neighborhood Hits	76	Target Neighborhood Hits	765	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

CNGB1_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.004653 (rank : 94)
Query Neighborhood Hits	76	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

ILDR1_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.009189 (rank : 81)
Query Neighborhood Hits	76	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

MYH9_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.004023 (rank : 95)
Query Neighborhood Hits	76	Target Neighborhood Hits	1829	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYO9B_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.003621 (rank : 97)
Query Neighborhood Hits	76	Target Neighborhood Hits	311	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

NCOA6_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.034384 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	1202	Shared Neighborhood Hits	16
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NEB2_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.003068 (rank : 100)
Query Neighborhood Hits	76	Target Neighborhood Hits	889	Shared Neighborhood Hits	14
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RAI14_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.002335 (rank : 101)
Query Neighborhood Hits	76	Target Neighborhood Hits	1505	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

WAPL_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.008626 (rank : 83)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

AKAP2_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.010892 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

ARHG8_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.012227 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

CTNA1_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.006075 (rank : 92)
Query Neighborhood Hits	76	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P35221, Q12795	Gene names	CTNNA1
Domain Architecture
Description	Catenin alpha-1 (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen).

CTNA1_MOUSE
θ value	8.99809 (rank : 70)	NC score	0.006082 (rank : 91)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	P26231	Gene names	Ctnna1, Catna1
Domain Architecture
Description	Catenin alpha-1 (102 kDa cadherin-associated protein) (CAP102) (Alpha E-catenin).

GRAM3_MOUSE
θ value	8.99809 (rank : 71)	NC score	0.007916 (rank : 88)
Query Neighborhood Hits	76	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEM6	Gene names	Gramd3
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3.

HOOK1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.007449 (rank : 89)
Query Neighborhood Hits	76	Target Neighborhood Hits	942	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

M4K1_HUMAN
θ value	8.99809 (rank : 73)	NC score	-0.001935 (rank : 104)
Query Neighborhood Hits	76	Target Neighborhood Hits	884	Shared Neighborhood Hits	4
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

PCNT_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.003161 (rank : 99)
Query Neighborhood Hits	76	Target Neighborhood Hits	1207	Shared Neighborhood Hits	16
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

TRIO_HUMAN
θ value	8.99809 (rank : 75)	NC score	-0.002301 (rank : 105)
Query Neighborhood Hits	76	Target Neighborhood Hits	1580	Shared Neighborhood Hits	18
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

ZEP2_HUMAN
θ value	8.99809 (rank : 76)	NC score	-0.001570 (rank : 103)
Query Neighborhood Hits	76	Target Neighborhood Hits	937	Shared Neighborhood Hits	8
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

3BP2_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.095088 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	296	Shared Neighborhood Hits	15
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.097562 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ANLN_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.100358 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	222	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANLN_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.080975 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	297	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CENB5_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.055140 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	395	Shared Neighborhood Hits	15
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CNKR1_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.162494 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	154	Shared Neighborhood Hits	18
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CNKR2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.085356 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.085481 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

DAPP1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.094771 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.099695 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

GNRP_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.050184 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	239	Shared Neighborhood Hits	15
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

GPS2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.050580 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	459	Shared Neighborhood Hits	10
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

PKHA1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.115880 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.115734 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA2_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.090969 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.102778 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA4_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.099195 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA4_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.107810 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA5_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.087561 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PKHA6_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.123409 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	556	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK2_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.085695 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	101	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.087141 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.113673 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.116410 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

RASA1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.067416 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RHG25_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.064285 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	550	Shared Neighborhood Hits	20
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.067527 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	492	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SWP70_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.061043 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	973	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.051836 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	1097	Shared Neighborhood Hits	26
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

Hits sorted by NC score

IQEC1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	76
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
NC score	0.997931 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	76	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC3_HUMAN
NC score	0.965990 (rank : 3)	θ value	1.12714e-143 (rank : 6)
Query Neighborhood Hits	76	Target Neighborhood Hits	125	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
NC score	0.951828 (rank : 4)	θ value	1.19867e-161 (rank : 5)
Query Neighborhood Hits	76	Target Neighborhood Hits	274	Shared Neighborhood Hits	26
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC2_HUMAN
NC score	0.946033 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	76	Target Neighborhood Hits	403	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
NC score	0.943602 (rank : 6)	θ value	0 (rank : 4)
Query Neighborhood Hits	76	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

GBF1_HUMAN
NC score	0.818949 (rank : 7)	θ value	5.22648e-32 (rank : 17)
Query Neighborhood Hits	76	Target Neighborhood Hits	142	Shared Neighborhood Hits	24
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

BIG1_HUMAN
NC score	0.817990 (rank : 8)	θ value	5.76516e-39 (rank : 13)
Query Neighborhood Hits	76	Target Neighborhood Hits	76	Shared Neighborhood Hits	25
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

CYH2_MOUSE
NC score	0.801339 (rank : 9)	θ value	2.76489e-41 (rank : 8)
Query Neighborhood Hits	76	Target Neighborhood Hits	171	Shared Neighborhood Hits	25
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH2_HUMAN
NC score	0.800901 (rank : 10)	θ value	2.11701e-41 (rank : 7)
Query Neighborhood Hits	76	Target Neighborhood Hits	175	Shared Neighborhood Hits	25
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

BIG2_HUMAN
NC score	0.799381 (rank : 11)	θ value	5.22648e-32 (rank : 16)
Query Neighborhood Hits	76	Target Neighborhood Hits	66	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

CYH3_HUMAN
NC score	0.795649 (rank : 12)	θ value	1.98146e-39 (rank : 11)
Query Neighborhood Hits	76	Target Neighborhood Hits	137	Shared Neighborhood Hits	25
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

CYH1_MOUSE
NC score	0.793483 (rank : 13)	θ value	6.81017e-40 (rank : 9)
Query Neighborhood Hits	76	Target Neighborhood Hits	176	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH4_MOUSE
NC score	0.790726 (rank : 14)	θ value	1.73584e-35 (rank : 14)
Query Neighborhood Hits	76	Target Neighborhood Hits	134	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

CYH1_HUMAN
NC score	0.790635 (rank : 15)	θ value	1.51715e-39 (rank : 10)
Query Neighborhood Hits	76	Target Neighborhood Hits	184	Shared Neighborhood Hits	25
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH4_HUMAN
NC score	0.790403 (rank : 16)	θ value	5.0505e-35 (rank : 15)
Query Neighborhood Hits	76	Target Neighborhood Hits	135	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

CYH3_MOUSE
NC score	0.789642 (rank : 17)	θ value	3.37985e-39 (rank : 12)
Query Neighborhood Hits	76	Target Neighborhood Hits	148	Shared Neighborhood Hits	25
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

FBX8_MOUSE
NC score	0.781334 (rank : 18)	θ value	4.29542e-18 (rank : 20)
Query Neighborhood Hits	76	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FBX8_HUMAN
NC score	0.779223 (rank : 19)	θ value	9.56915e-18 (rank : 21)
Query Neighborhood Hits	76	Target Neighborhood Hits	44	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

PSD3_HUMAN
NC score	0.730433 (rank : 20)	θ value	4.74913e-17 (rank : 22)
Query Neighborhood Hits	76	Target Neighborhood Hits	75	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_MOUSE
NC score	0.701152 (rank : 21)	θ value	8.65492e-19 (rank : 19)
Query Neighborhood Hits	76	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

PSD4_HUMAN
NC score	0.691223 (rank : 22)	θ value	6.62687e-19 (rank : 18)
Query Neighborhood Hits	76	Target Neighborhood Hits	178	Shared Neighborhood Hits	25
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

CNKR1_HUMAN
NC score	0.162494 (rank : 23)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	76	Target Neighborhood Hits	154	Shared Neighborhood Hits	18
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

PKHA6_HUMAN
NC score	0.123409 (rank : 24)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	76	Target Neighborhood Hits	556	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA6_MOUSE
NC score	0.119804 (rank : 25)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	76	Target Neighborhood Hits	591	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PLEK_MOUSE
NC score	0.116410 (rank : 26)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	76	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PKHA1_HUMAN
NC score	0.115880 (rank : 27)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	76	Target Neighborhood Hits	127	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.115734 (rank : 28)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	76	Target Neighborhood Hits	120	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PLEK_HUMAN
NC score	0.113673 (rank : 29)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	76	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PKHA4_MOUSE
NC score	0.107810 (rank : 30)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	76	Target Neighborhood Hits	202	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

PKHA2_MOUSE
NC score	0.102778 (rank : 31)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	76	Target Neighborhood Hits	116	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

ANLN_HUMAN
NC score	0.100358 (rank : 32)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	76	Target Neighborhood Hits	222	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DAPP1_MOUSE
NC score	0.099695 (rank : 33)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	76	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA4_HUMAN
NC score	0.099195 (rank : 34)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	76	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

3BP2_MOUSE
NC score	0.097562 (rank : 35)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	76	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_HUMAN
NC score	0.095088 (rank : 36)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	76	Target Neighborhood Hits	296	Shared Neighborhood Hits	15
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

DAPP1_HUMAN
NC score	0.094771 (rank : 37)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	76	Target Neighborhood Hits	227	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA2_HUMAN
NC score	0.090969 (rank : 38)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	76	Target Neighborhood Hits	119	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA5_HUMAN
NC score	0.087561 (rank : 39)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	76	Target Neighborhood Hits	455	Shared Neighborhood Hits	23
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

PLEK2_MOUSE
NC score	0.087141 (rank : 40)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	76	Target Neighborhood Hits	96	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

PLEK2_HUMAN
NC score	0.085695 (rank : 41)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	76	Target Neighborhood Hits	101	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

CNKR2_MOUSE
NC score	0.085481 (rank : 42)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	76	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.085356 (rank : 43)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	76	Target Neighborhood Hits	197	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

ANLN_MOUSE
NC score	0.080975 (rank : 44)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	76	Target Neighborhood Hits	297	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

RHG25_MOUSE
NC score	0.067527 (rank : 45)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	76	Target Neighborhood Hits	492	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RASA1_HUMAN
NC score	0.067416 (rank : 46)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	76	Target Neighborhood Hits	258	Shared Neighborhood Hits	10
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

CENB2_HUMAN
NC score	0.064559 (rank : 47)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	76	Target Neighborhood Hits	425	Shared Neighborhood Hits	18
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

RHG25_HUMAN
NC score	0.064285 (rank : 48)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	76	Target Neighborhood Hits	550	Shared Neighborhood Hits	20
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

SWP70_HUMAN
NC score	0.061043 (rank : 49)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	76	Target Neighborhood Hits	973	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CENB5_HUMAN
NC score	0.055140 (rank : 50)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	76	Target Neighborhood Hits	395	Shared Neighborhood Hits	15
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

SWP70_MOUSE
NC score	0.051836 (rank : 51)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	76	Target Neighborhood Hits	1097	Shared Neighborhood Hits	26
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

GPS2_HUMAN
NC score	0.050580 (rank : 52)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	76	Target Neighborhood Hits	459	Shared Neighborhood Hits	10
SwissProt Accessions	Q13227	Gene names	GPS2
Domain Architecture	No domain graphic available
Description	G protein pathway suppressor 2 (Protein GPS2).

GNRP_HUMAN
NC score	0.050184 (rank : 53)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	76	Target Neighborhood Hits	239	Shared Neighborhood Hits	15
SwissProt Accessions	Q13972, Q16027	Gene names	RASGRF1, CDC25
Domain Architecture
Description	Guanine nucleotide-releasing protein (GNRP) (Ras-specific nucleotide exchange factor CDC25) (Ras-specific guanine nucleotide-releasing factor).

CE025_HUMAN
NC score	0.041533 (rank : 54)	θ value	0.163984 (rank : 23)
Query Neighborhood Hits	76	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

FARP1_HUMAN
NC score	0.037910 (rank : 55)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	76	Target Neighborhood Hits	241	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

NCOA6_HUMAN
NC score	0.034384 (rank : 56)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	76	Target Neighborhood Hits	1202	Shared Neighborhood Hits	16
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

ARHGG_MOUSE
NC score	0.030116 (rank : 57)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	76	Target Neighborhood Hits	152	Shared Neighborhood Hits	10
SwissProt Accessions	Q3U5C8, Q501M8, Q8VCE8	Gene names	Arhgef16
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

CF203_MOUSE
NC score	0.029098 (rank : 58)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	76	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CQF4, Q3TQU4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf203 homolog.

GOSR2_HUMAN
NC score	0.028338 (rank : 59)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	76	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O14653, Q96DA5, Q9BZZ4	Gene names	GOSR2, GS27
Domain Architecture
Description	Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin).

MLL3_HUMAN
NC score	0.026537 (rank : 60)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	76	Target Neighborhood Hits	1644	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

THEX1_HUMAN
NC score	0.024532 (rank : 61)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	76	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IV48, Q9NSX3	Gene names	THEX1, 3'EXO, ERI1
Domain Architecture
Description	3' histone mRNA exonuclease 1 (EC 3.1.-.-) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3' end-specific exoribonuclease) (Protein 3'hExo) (HEXO).

DPPA2_HUMAN
NC score	0.024008 (rank : 62)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	76	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z7J5, Q8WVF0	Gene names	DPPA2, PESCRG1
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 2 (Pluripotent embryonic stem cell-related protein 1).

AKAP2_MOUSE
NC score	0.023800 (rank : 63)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	76	Target Neighborhood Hits	385	Shared Neighborhood Hits	14
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

AMOL1_MOUSE
NC score	0.022182 (rank : 64)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	76	Target Neighborhood Hits	445	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

HRX_HUMAN
NC score	0.021580 (rank : 65)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	76	Target Neighborhood Hits	825	Shared Neighborhood Hits	8
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ATF6B_MOUSE
NC score	0.020906 (rank : 66)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	76	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

BIN1_MOUSE
NC score	0.019289 (rank : 67)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	76	Target Neighborhood Hits	283	Shared Neighborhood Hits	8
SwissProt Accessions	O08539, Q62434	Gene names	Bin1, Amphl, Sh3p9
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (SH3-domain-containing protein 9).

TNR11_HUMAN
NC score	0.019098 (rank : 68)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	76	Target Neighborhood Hits	135	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6Q6	Gene names	TNFRSF11A, RANK
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 11A precursor (Receptor activator of NF-KB) (Osteoclast differentiation factor receptor) (ODFR) (CD265 antigen).

GP124_MOUSE
NC score	0.017512 (rank : 69)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	76	Target Neighborhood Hits	423	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

AMOL1_HUMAN
NC score	0.016588 (rank : 70)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	76	Target Neighborhood Hits	435	Shared Neighborhood Hits	18
SwissProt Accessions	Q8IY63, Q63HK7, Q8NDN0, Q8WXD1, Q96CM5	Gene names	AMOTL1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

IER2_MOUSE
NC score	0.016374 (rank : 71)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	76	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P17950, Q64251, Q8BME8, Q99M25	Gene names	Ier2
Domain Architecture
Description	Immediate early response gene 2 protein (T-lymphocyte-activated protein) (Cycloheximide-induced gene protein) (CHX1) (Growth factor- inducible immediate early protein) (Proline-rich-induced protein 92) (Pip92).

DDHD1_HUMAN
NC score	0.013167 (rank : 72)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	76	Target Neighborhood Hits	40	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEL9, Q8WVH3, Q96LL2, Q9C0F8	Gene names	DDHD1, KIAA1705
Domain Architecture
Description	Probable phospholipase DDHD1 (EC 3.1.1.-) (DDHD domain protein 1) (Phosphatidic acid-preferring phospholipase A1 homolog) (PA-PLA1).

ARHGG_HUMAN
NC score	0.012457 (rank : 73)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	76	Target Neighborhood Hits	129	Shared Neighborhood Hits	8
SwissProt Accessions	Q5VV41, Q86TF0, Q99434	Gene names	ARHGEF16, NBR
Domain Architecture	No domain graphic available
Description	Rho guanine nucleotide exchange factor 16.

ARI4A_HUMAN
NC score	0.012231 (rank : 74)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	76	Target Neighborhood Hits	434	Shared Neighborhood Hits	13
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ARHG8_HUMAN
NC score	0.012227 (rank : 75)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	76	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z628, Q12773, Q96D82, Q99903, Q9UEN6	Gene names	NET1, ARHGEF8
Domain Architecture	No domain graphic available
Description	Neuroepithelial cell-transforming gene 1 protein (p65 Net1 proto- oncogene) (Rho guanine nucleotide exchange factor 8).

K0195_HUMAN
NC score	0.011522 (rank : 76)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	76	Target Neighborhood Hits	61	Shared Neighborhood Hits	2
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

ASPM_HUMAN
NC score	0.011138 (rank : 77)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	76	Target Neighborhood Hits	197	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZT6, Q86UX4, Q8IUL2, Q8IZJ7, Q8IZJ8, Q8IZJ9, Q8N4D1, Q9NVS1, Q9NVT6	Gene names	ASPM, MCPH5
Domain Architecture
Description	Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog).

AKAP2_HUMAN
NC score	0.010892 (rank : 78)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	76	Target Neighborhood Hits	507	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

PCLO_HUMAN
NC score	0.009660 (rank : 79)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	76	Target Neighborhood Hits	2046	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

HOOK2_HUMAN
NC score	0.009290 (rank : 80)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	76	Target Neighborhood Hits	714	Shared Neighborhood Hits	15
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

ILDR1_MOUSE
NC score	0.009189 (rank : 81)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	76	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CBR1, Q6PFB3, Q8CB39, Q91VS0	Gene names	Ildr1
Domain Architecture	No domain graphic available
Description	Immunoglobulin-like domain-containing receptor 1 precursor.

NOLC1_HUMAN
NC score	0.008749 (rank : 82)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	76	Target Neighborhood Hits	452	Shared Neighborhood Hits	9
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

WAPL_MOUSE
NC score	0.008626 (rank : 83)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	76	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q65Z40, Q6ZQE9	Gene names	Wapal, Kiaa0261, Wapl
Domain Architecture	No domain graphic available
Description	Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2).

ANKS3_MOUSE
NC score	0.008269 (rank : 84)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	76	Target Neighborhood Hits	355	Shared Neighborhood Hits	7
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

CCD41_MOUSE
NC score	0.008161 (rank : 85)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	76	Target Neighborhood Hits	1399	Shared Neighborhood Hits	22
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

ATN1_HUMAN
NC score	0.008042 (rank : 86)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	76	Target Neighborhood Hits	676	Shared Neighborhood Hits	10
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

LMNB1_MOUSE
NC score	0.007979 (rank : 87)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	76	Target Neighborhood Hits	719	Shared Neighborhood Hits	13
SwissProt Accessions	P14733, Q61791	Gene names	Lmnb1
Domain Architecture
Description	Lamin-B1.

GRAM3_MOUSE
NC score	0.007916 (rank : 88)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	76	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEM6	Gene names	Gramd3
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3.

HOOK1_HUMAN
NC score	0.007449 (rank : 89)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	76	Target Neighborhood Hits	942	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

DSPP_MOUSE
NC score	0.006828 (rank : 90)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	76	Target Neighborhood Hits	491	Shared Neighborhood Hits	9
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CTNA1_MOUSE
NC score	0.006082 (rank : 91)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	76	Target Neighborhood Hits	84	Shared Neighborhood Hits	6
SwissProt Accessions	P26231	Gene names	Ctnna1, Catna1
Domain Architecture
Description	Catenin alpha-1 (102 kDa cadherin-associated protein) (CAP102) (Alpha E-catenin).

CTNA1_HUMAN
NC score	0.006075 (rank : 92)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	76	Target Neighborhood Hits	83	Shared Neighborhood Hits	6
SwissProt Accessions	P35221, Q12795	Gene names	CTNNA1
Domain Architecture
Description	Catenin alpha-1 (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen).

LMNB1_HUMAN
NC score	0.006020 (rank : 93)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	76	Target Neighborhood Hits	714	Shared Neighborhood Hits	14
SwissProt Accessions	P20700, Q3SYN7, Q96EI6	Gene names	LMNB1, LMN2, LMNB
Domain Architecture
Description	Lamin-B1.

CNGB1_HUMAN
NC score	0.004653 (rank : 94)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	76	Target Neighborhood Hits	222	Shared Neighborhood Hits	8
SwissProt Accessions	Q14028, Q14029	Gene names	CNGB1, CNCG4
Domain Architecture
Description	Cyclic nucleotide-gated cation channel 4 (CNG channel 4) (CNG-4) (CNG4) (Cyclic nucleotide-gated cation channel modulatory subunit).

MYH9_MOUSE
NC score	0.004023 (rank : 95)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	76	Target Neighborhood Hits	1829	Shared Neighborhood Hits	27
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ANR12_HUMAN
NC score	0.003957 (rank : 96)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	76	Target Neighborhood Hits	1081	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

MYO9B_MOUSE
NC score	0.003621 (rank : 97)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	76	Target Neighborhood Hits	311	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

CENPF_HUMAN
NC score	0.003260 (rank : 98)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	76	Target Neighborhood Hits	1932	Shared Neighborhood Hits	27
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PCNT_MOUSE
NC score	0.003161 (rank : 99)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	76	Target Neighborhood Hits	1207	Shared Neighborhood Hits	16
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

NEB2_MOUSE
NC score	0.003068 (rank : 100)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	76	Target Neighborhood Hits	889	Shared Neighborhood Hits	14
SwissProt Accessions	Q6R891, Q8K0X7	Gene names	Ppp1r9b
Domain Architecture	No domain graphic available
Description	Neurabin-2 (Neurabin-II) (Spinophilin) (Protein phosphatase 1 regulatory subunit 9B).

RAI14_MOUSE
NC score	0.002335 (rank : 101)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	76	Target Neighborhood Hits	1505	Shared Neighborhood Hits	25
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

POGZ_MOUSE
NC score	-0.000721 (rank : 102)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	76	Target Neighborhood Hits	765	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZH4, Q4VA94, Q80TZ8, Q8C0K1, Q8K294	Gene names	Pogz, Kiaa0461
Domain Architecture
Description	Pogo transposable element with ZNF domain.

ZEP2_HUMAN
NC score	-0.001570 (rank : 103)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	76	Target Neighborhood Hits	937	Shared Neighborhood Hits	8
SwissProt Accessions	P31629, Q02646, Q5THT5, Q9NS05	Gene names	HIVEP2
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 (HIV- EP2) (MHC-binding protein 2) (MBP-2).

M4K1_HUMAN
NC score	-0.001935 (rank : 104)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	76	Target Neighborhood Hits	884	Shared Neighborhood Hits	4
SwissProt Accessions	Q92918	Gene names	MAP4K1, HPK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 1 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 1) (MEK kinase kinase 1) (MEKKK 1) (Hematopoietic progenitor kinase).

TRIO_HUMAN
NC score	-0.002301 (rank : 105)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	76	Target Neighborhood Hits	1580	Shared Neighborhood Hits	18
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).