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Network neighborhood for query Sequence : CENB5_HUMAN

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CENB5_HUMAN
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CENB2_HUMAN
θ value	0 (rank : 1)	NC score	0.975300 (rank : 2)
Query Neighborhood Hits	395	Target Neighborhood Hits	425	Shared Neighborhood Hits	332
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	395	Target Neighborhood Hits	395	Shared Neighborhood Hits	395
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB1_HUMAN
θ value	6.40027e-139 (rank : 3)	NC score	0.967481 (rank : 3)
Query Neighborhood Hits	395	Target Neighborhood Hits	383	Shared Neighborhood Hits	335
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DDEF2_HUMAN
θ value	2.85459e-46 (rank : 4)	NC score	0.786941 (rank : 6)
Query Neighborhood Hits	395	Target Neighborhood Hits	599	Shared Neighborhood Hits	273
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	1.41672e-45 (rank : 5)	NC score	0.806429 (rank : 5)
Query Neighborhood Hits	395	Target Neighborhood Hits	353	Shared Neighborhood Hits	264
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	5.38352e-45 (rank : 6)	NC score	0.830829 (rank : 4)
Query Neighborhood Hits	395	Target Neighborhood Hits	324	Shared Neighborhood Hits	275
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DDEF2_MOUSE
θ value	1.19932e-44 (rank : 7)	NC score	0.781526 (rank : 7)
Query Neighborhood Hits	395	Target Neighborhood Hits	625	Shared Neighborhood Hits	273
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF1_MOUSE
θ value	6.58091e-43 (rank : 8)	NC score	0.738364 (rank : 8)
Query Neighborhood Hits	395	Target Neighborhood Hits	592	Shared Neighborhood Hits	235
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

CENG2_HUMAN
θ value	5.584e-34 (rank : 9)	NC score	0.695670 (rank : 18)
Query Neighborhood Hits	395	Target Neighborhood Hits	471	Shared Neighborhood Hits	267
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG3_MOUSE
θ value	5.584e-34 (rank : 10)	NC score	0.697283 (rank : 15)
Query Neighborhood Hits	395	Target Neighborhood Hits	467	Shared Neighborhood Hits	244
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG1_MOUSE
θ value	9.52487e-34 (rank : 11)	NC score	0.720326 (rank : 10)
Query Neighborhood Hits	395	Target Neighborhood Hits	531	Shared Neighborhood Hits	254
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG3_HUMAN
θ value	1.24399e-33 (rank : 12)	NC score	0.697021 (rank : 16)
Query Neighborhood Hits	395	Target Neighborhood Hits	455	Shared Neighborhood Hits	244
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG1_HUMAN
θ value	2.77131e-33 (rank : 13)	NC score	0.713684 (rank : 13)
Query Neighborhood Hits	395	Target Neighborhood Hits	544	Shared Neighborhood Hits	256
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENG2_MOUSE
θ value	2.77131e-33 (rank : 14)	NC score	0.696783 (rank : 17)
Query Neighborhood Hits	395	Target Neighborhood Hits	463	Shared Neighborhood Hits	266
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CEND2_HUMAN
θ value	3.75424e-22 (rank : 15)	NC score	0.502373 (rank : 176)
Query Neighborhood Hits	395	Target Neighborhood Hits	166	Shared Neighborhood Hits	79
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

SMAP1_MOUSE
θ value	1.09232e-21 (rank : 16)	NC score	0.625333 (rank : 20)
Query Neighborhood Hits	395	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

DP13A_MOUSE
θ value	2.43343e-21 (rank : 17)	NC score	0.380877 (rank : 241)
Query Neighborhood Hits	395	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

RHG26_HUMAN
θ value	2.43343e-21 (rank : 18)	NC score	0.264139 (rank : 294)
Query Neighborhood Hits	395	Target Neighborhood Hits	281	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

SMP1L_HUMAN
θ value	3.17815e-21 (rank : 19)	NC score	0.623539 (rank : 21)
Query Neighborhood Hits	395	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	3.17815e-21 (rank : 20)	NC score	0.622421 (rank : 22)
Query Neighborhood Hits	395	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_HUMAN
θ value	7.0802e-21 (rank : 21)	NC score	0.622300 (rank : 23)
Query Neighborhood Hits	395	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CEND1_MOUSE
θ value	9.24701e-21 (rank : 22)	NC score	0.511814 (rank : 170)
Query Neighborhood Hits	395	Target Neighborhood Hits	260	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

DP13A_HUMAN
θ value	9.24701e-21 (rank : 23)	NC score	0.379676 (rank : 242)
Query Neighborhood Hits	395	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13B_HUMAN
θ value	1.2077e-20 (rank : 24)	NC score	0.369168 (rank : 252)
Query Neighborhood Hits	395	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

CEND1_HUMAN
θ value	1.5773e-20 (rank : 25)	NC score	0.518903 (rank : 167)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

CENA1_HUMAN
θ value	2.27762e-19 (rank : 26)	NC score	0.637848 (rank : 19)
Query Neighborhood Hits	395	Target Neighborhood Hits	87	Shared Neighborhood Hits	78
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

OPHN1_MOUSE
θ value	2.27762e-19 (rank : 27)	NC score	0.286031 (rank : 283)
Query Neighborhood Hits	395	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_HUMAN
θ value	3.88503e-19 (rank : 28)	NC score	0.273263 (rank : 287)
Query Neighborhood Hits	395	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

DP13B_MOUSE
θ value	8.65492e-19 (rank : 29)	NC score	0.376822 (rank : 246)
Query Neighborhood Hits	395	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

CEND3_HUMAN
θ value	1.058e-16 (rank : 30)	NC score	0.484943 (rank : 187)
Query Neighborhood Hits	395	Target Neighborhood Hits	275	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

CENA2_MOUSE
θ value	1.80466e-16 (rank : 31)	NC score	0.600354 (rank : 28)
Query Neighborhood Hits	395	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

CENA2_HUMAN
θ value	6.85773e-16 (rank : 32)	NC score	0.603510 (rank : 27)
Query Neighborhood Hits	395	Target Neighborhood Hits	83	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

GIT1_HUMAN
θ value	2.60593e-15 (rank : 33)	NC score	0.716642 (rank : 12)
Query Neighborhood Hits	395	Target Neighborhood Hits	336	Shared Neighborhood Hits	263
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	2.60593e-15 (rank : 34)	NC score	0.717046 (rank : 11)
Query Neighborhood Hits	395	Target Neighborhood Hits	341	Shared Neighborhood Hits	264
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT2_HUMAN
θ value	5.8054e-15 (rank : 35)	NC score	0.710304 (rank : 14)
Query Neighborhood Hits	395	Target Neighborhood Hits	381	Shared Neighborhood Hits	258
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

GIT2_MOUSE
θ value	5.8054e-15 (rank : 36)	NC score	0.731166 (rank : 9)
Query Neighborhood Hits	395	Target Neighborhood Hits	323	Shared Neighborhood Hits	260
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

CEND3_MOUSE
θ value	7.58209e-15 (rank : 37)	NC score	0.479010 (rank : 191)
Query Neighborhood Hits	395	Target Neighborhood Hits	228	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

ARFG3_MOUSE
θ value	9.90251e-15 (rank : 38)	NC score	0.574080 (rank : 71)
Query Neighborhood Hits	395	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_HUMAN
θ value	1.29331e-14 (rank : 39)	NC score	0.577510 (rank : 64)
Query Neighborhood Hits	395	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG1_MOUSE
θ value	4.91457e-14 (rank : 40)	NC score	0.586506 (rank : 44)
Query Neighborhood Hits	395	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ARFG1_HUMAN
θ value	8.38298e-14 (rank : 41)	NC score	0.574700 (rank : 68)
Query Neighborhood Hits	395	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

UACA_HUMAN
θ value	5.62301e-10 (rank : 42)	NC score	0.370992 (rank : 250)
Query Neighborhood Hits	395	Target Neighborhood Hits	1622	Shared Neighborhood Hits	296
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

RAI14_HUMAN
θ value	7.34386e-10 (rank : 43)	NC score	0.460503 (rank : 210)
Query Neighborhood Hits	395	Target Neighborhood Hits	1367	Shared Neighborhood Hits	301
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

RAI14_MOUSE
θ value	7.34386e-10 (rank : 44)	NC score	0.436035 (rank : 218)
Query Neighborhood Hits	395	Target Neighborhood Hits	1505	Shared Neighborhood Hits	296
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR44_HUMAN
θ value	2.13673e-09 (rank : 45)	NC score	0.584113 (rank : 47)
Query Neighborhood Hits	395	Target Neighborhood Hits	318	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANK1_HUMAN
θ value	2.79066e-09 (rank : 46)	NC score	0.578082 (rank : 61)
Query Neighborhood Hits	395	Target Neighborhood Hits	416	Shared Neighborhood Hits	261
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR50_HUMAN
θ value	2.79066e-09 (rank : 47)	NC score	0.589447 (rank : 39)
Query Neighborhood Hits	395	Target Neighborhood Hits	361	Shared Neighborhood Hits	263
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANK1_MOUSE
θ value	8.11959e-09 (rank : 48)	NC score	0.576396 (rank : 67)
Query Neighborhood Hits	395	Target Neighborhood Hits	430	Shared Neighborhood Hits	261
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ANR52_HUMAN
θ value	1.06045e-08 (rank : 49)	NC score	0.582011 (rank : 51)
Query Neighborhood Hits	395	Target Neighborhood Hits	322	Shared Neighborhood Hits	260
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_MOUSE
θ value	1.06045e-08 (rank : 50)	NC score	0.582402 (rank : 49)
Query Neighborhood Hits	395	Target Neighborhood Hits	318	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

TNKS2_HUMAN
θ value	1.38499e-08 (rank : 51)	NC score	0.587380 (rank : 42)
Query Neighborhood Hits	395	Target Neighborhood Hits	361	Shared Neighborhood Hits	266
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

UACA_MOUSE
θ value	1.38499e-08 (rank : 52)	NC score	0.351951 (rank : 260)
Query Neighborhood Hits	395	Target Neighborhood Hits	1620	Shared Neighborhood Hits	292
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ANKR5_MOUSE
θ value	2.36244e-08 (rank : 53)	NC score	0.579502 (rank : 58)
Query Neighborhood Hits	395	Target Neighborhood Hits	298	Shared Neighborhood Hits	256
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

PKHA6_HUMAN
θ value	4.0297e-08 (rank : 54)	NC score	0.225298 (rank : 306)
Query Neighborhood Hits	395	Target Neighborhood Hits	556	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

ANKK1_HUMAN
θ value	8.97725e-08 (rank : 55)	NC score	0.364156 (rank : 254)
Query Neighborhood Hits	395	Target Neighborhood Hits	1075	Shared Neighborhood Hits	262
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ANR28_MOUSE
θ value	8.97725e-08 (rank : 56)	NC score	0.581469 (rank : 53)
Query Neighborhood Hits	395	Target Neighborhood Hits	314	Shared Neighborhood Hits	261
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKK1_MOUSE
θ value	1.17247e-07 (rank : 57)	NC score	0.356639 (rank : 257)
Query Neighborhood Hits	395	Target Neighborhood Hits	1072	Shared Neighborhood Hits	262
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

MYPT2_HUMAN
θ value	1.17247e-07 (rank : 58)	NC score	0.562169 (rank : 93)
Query Neighborhood Hits	395	Target Neighborhood Hits	707	Shared Neighborhood Hits	274
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

TNKS1_HUMAN
θ value	1.53129e-07 (rank : 59)	NC score	0.587962 (rank : 41)
Query Neighborhood Hits	395	Target Neighborhood Hits	477	Shared Neighborhood Hits	267
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

EHMT2_MOUSE
θ value	1.99992e-07 (rank : 60)	NC score	0.529551 (rank : 153)
Query Neighborhood Hits	395	Target Neighborhood Hits	750	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

HECD1_HUMAN
θ value	1.99992e-07 (rank : 61)	NC score	0.454440 (rank : 212)
Query Neighborhood Hits	395	Target Neighborhood Hits	371	Shared Neighborhood Hits	253
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

PP16A_MOUSE
θ value	1.99992e-07 (rank : 62)	NC score	0.566199 (rank : 85)
Query Neighborhood Hits	395	Target Neighborhood Hits	318	Shared Neighborhood Hits	258
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

EHMT2_HUMAN
θ value	2.61198e-07 (rank : 63)	NC score	0.542897 (rank : 127)
Query Neighborhood Hits	395	Target Neighborhood Hits	498	Shared Neighborhood Hits	264
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANKR5_HUMAN
θ value	3.41135e-07 (rank : 64)	NC score	0.577386 (rank : 66)
Query Neighborhood Hits	395	Target Neighborhood Hits	297	Shared Neighborhood Hits	257
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANR35_HUMAN
θ value	4.45536e-07 (rank : 65)	NC score	0.552622 (rank : 106)
Query Neighborhood Hits	395	Target Neighborhood Hits	784	Shared Neighborhood Hits	288
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

MYPT1_HUMAN
θ value	4.45536e-07 (rank : 66)	NC score	0.569778 (rank : 79)
Query Neighborhood Hits	395	Target Neighborhood Hits	723	Shared Neighborhood Hits	277
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

MYPT1_MOUSE
θ value	4.45536e-07 (rank : 67)	NC score	0.581319 (rank : 54)
Query Neighborhood Hits	395	Target Neighborhood Hits	539	Shared Neighborhood Hits	271
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PKHA6_MOUSE
θ value	4.45536e-07 (rank : 68)	NC score	0.227012 (rank : 304)
Query Neighborhood Hits	395	Target Neighborhood Hits	591	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

ANKR2_MOUSE
θ value	5.81887e-07 (rank : 69)	NC score	0.585581 (rank : 46)
Query Neighborhood Hits	395	Target Neighborhood Hits	312	Shared Neighborhood Hits	261
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ASB2_HUMAN
θ value	7.59969e-07 (rank : 70)	NC score	0.568829 (rank : 80)
Query Neighborhood Hits	395	Target Neighborhood Hits	309	Shared Neighborhood Hits	259
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

TNI3K_HUMAN
θ value	7.59969e-07 (rank : 71)	NC score	0.293953 (rank : 280)
Query Neighborhood Hits	395	Target Neighborhood Hits	1084	Shared Neighborhood Hits	262
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKR2_HUMAN
θ value	9.92553e-07 (rank : 72)	NC score	0.588786 (rank : 40)
Query Neighborhood Hits	395	Target Neighborhood Hits	321	Shared Neighborhood Hits	262
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

CDN2D_HUMAN
θ value	9.92553e-07 (rank : 73)	NC score	0.579400 (rank : 59)
Query Neighborhood Hits	395	Target Neighborhood Hits	268	Shared Neighborhood Hits	246
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CSKI2_HUMAN
θ value	9.92553e-07 (rank : 74)	NC score	0.541233 (rank : 131)
Query Neighborhood Hits	395	Target Neighborhood Hits	747	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANK2_HUMAN
θ value	1.29631e-06 (rank : 75)	NC score	0.531507 (rank : 149)
Query Neighborhood Hits	395	Target Neighborhood Hits	1615	Shared Neighborhood Hits	285
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANRA2_MOUSE
θ value	1.29631e-06 (rank : 76)	NC score	0.574140 (rank : 70)
Query Neighborhood Hits	395	Target Neighborhood Hits	287	Shared Neighborhood Hits	252
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANS4B_MOUSE
θ value	1.29631e-06 (rank : 77)	NC score	0.569877 (rank : 78)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	241
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CSKI2_MOUSE
θ value	1.29631e-06 (rank : 78)	NC score	0.540702 (rank : 133)
Query Neighborhood Hits	395	Target Neighborhood Hits	812	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANR29_HUMAN
θ value	1.69304e-06 (rank : 79)	NC score	0.585690 (rank : 45)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANR47_MOUSE
θ value	1.69304e-06 (rank : 80)	NC score	0.489285 (rank : 183)
Query Neighborhood Hits	395	Target Neighborhood Hits	350	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

A20A3_HUMAN
θ value	2.88788e-06 (rank : 81)	NC score	0.476083 (rank : 195)
Query Neighborhood Hits	395	Target Neighborhood Hits	692	Shared Neighborhood Hits	274
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	2.88788e-06 (rank : 82)	NC score	0.472699 (rank : 200)
Query Neighborhood Hits	395	Target Neighborhood Hits	710	Shared Neighborhood Hits	274
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR28_HUMAN
θ value	2.88788e-06 (rank : 83)	NC score	0.579904 (rank : 56)
Query Neighborhood Hits	395	Target Neighborhood Hits	314	Shared Neighborhood Hits	261
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANK3_HUMAN
θ value	3.77169e-06 (rank : 84)	NC score	0.562982 (rank : 90)
Query Neighborhood Hits	395	Target Neighborhood Hits	853	Shared Neighborhood Hits	273
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANRA2_HUMAN
θ value	3.77169e-06 (rank : 85)	NC score	0.573382 (rank : 75)
Query Neighborhood Hits	395	Target Neighborhood Hits	288	Shared Neighborhood Hits	251
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

BCL3_HUMAN
θ value	3.77169e-06 (rank : 86)	NC score	0.574666 (rank : 69)
Query Neighborhood Hits	395	Target Neighborhood Hits	324	Shared Neighborhood Hits	259
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

GABP2_HUMAN
θ value	3.77169e-06 (rank : 87)	NC score	0.593851 (rank : 35)
Query Neighborhood Hits	395	Target Neighborhood Hits	454	Shared Neighborhood Hits	267
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

NUPL_HUMAN
θ value	3.77169e-06 (rank : 88)	NC score	0.405287 (rank : 228)
Query Neighborhood Hits	395	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NUPL_MOUSE
θ value	3.77169e-06 (rank : 89)	NC score	0.400867 (rank : 230)
Query Neighborhood Hits	395	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

AN36B_HUMAN
θ value	4.92598e-06 (rank : 90)	NC score	0.554363 (rank : 102)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANS4B_HUMAN
θ value	4.92598e-06 (rank : 91)	NC score	0.566645 (rank : 83)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	247
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ASB2_MOUSE
θ value	4.92598e-06 (rank : 92)	NC score	0.559355 (rank : 96)
Query Neighborhood Hits	395	Target Neighborhood Hits	321	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

CDN2D_MOUSE
θ value	4.92598e-06 (rank : 93)	NC score	0.565994 (rank : 86)
Query Neighborhood Hits	395	Target Neighborhood Hits	267	Shared Neighborhood Hits	244
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

CYH3_HUMAN
θ value	4.92598e-06 (rank : 94)	NC score	0.168926 (rank : 323)
Query Neighborhood Hits	395	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

GABP2_MOUSE
θ value	4.92598e-06 (rank : 95)	NC score	0.594445 (rank : 34)
Query Neighborhood Hits	395	Target Neighborhood Hits	429	Shared Neighborhood Hits	266
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GABP3_MOUSE
θ value	4.92598e-06 (rank : 96)	NC score	0.596956 (rank : 30)
Query Neighborhood Hits	395	Target Neighborhood Hits	330	Shared Neighborhood Hits	261
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

PSD10_HUMAN
θ value	4.92598e-06 (rank : 97)	NC score	0.598479 (rank : 29)
Query Neighborhood Hits	395	Target Neighborhood Hits	301	Shared Neighborhood Hits	260
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

A20A1_HUMAN
θ value	6.43352e-06 (rank : 98)	NC score	0.473980 (rank : 198)
Query Neighborhood Hits	395	Target Neighborhood Hits	698	Shared Neighborhood Hits	273
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
θ value	6.43352e-06 (rank : 99)	NC score	0.476371 (rank : 194)
Query Neighborhood Hits	395	Target Neighborhood Hits	716	Shared Neighborhood Hits	275
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

PSD10_MOUSE
θ value	6.43352e-06 (rank : 100)	NC score	0.596649 (rank : 32)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR42_MOUSE
θ value	8.40245e-06 (rank : 101)	NC score	0.579221 (rank : 60)
Query Neighborhood Hits	395	Target Neighborhood Hits	334	Shared Neighborhood Hits	260
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR47_HUMAN
θ value	8.40245e-06 (rank : 102)	NC score	0.471581 (rank : 203)
Query Neighborhood Hits	395	Target Neighborhood Hits	369	Shared Neighborhood Hits	244
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

BARD1_HUMAN
θ value	8.40245e-06 (rank : 103)	NC score	0.553038 (rank : 103)
Query Neighborhood Hits	395	Target Neighborhood Hits	427	Shared Neighborhood Hits	259
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

SHAN1_HUMAN
θ value	8.40245e-06 (rank : 104)	NC score	0.487386 (rank : 184)
Query Neighborhood Hits	395	Target Neighborhood Hits	1041	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

PKHA2_HUMAN
θ value	1.09739e-05 (rank : 105)	NC score	0.222022 (rank : 307)
Query Neighborhood Hits	395	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

PKHA2_MOUSE
θ value	1.09739e-05 (rank : 106)	NC score	0.226619 (rank : 305)
Query Neighborhood Hits	395	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

RN5A_HUMAN
θ value	1.09739e-05 (rank : 107)	NC score	0.537437 (rank : 136)
Query Neighborhood Hits	395	Target Neighborhood Hits	608	Shared Neighborhood Hits	258
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB3_MOUSE
θ value	1.43324e-05 (rank : 108)	NC score	0.577411 (rank : 65)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

INVS_MOUSE
θ value	1.43324e-05 (rank : 109)	NC score	0.563322 (rank : 89)
Query Neighborhood Hits	395	Target Neighborhood Hits	609	Shared Neighborhood Hits	262
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANR23_HUMAN
θ value	1.87187e-05 (rank : 110)	NC score	0.587115 (rank : 43)
Query Neighborhood Hits	395	Target Neighborhood Hits	291	Shared Neighborhood Hits	258
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

BARD1_MOUSE
θ value	1.87187e-05 (rank : 111)	NC score	0.550000 (rank : 113)
Query Neighborhood Hits	395	Target Neighborhood Hits	411	Shared Neighborhood Hits	255
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

CSKI1_HUMAN
θ value	1.87187e-05 (rank : 112)	NC score	0.533673 (rank : 144)
Query Neighborhood Hits	395	Target Neighborhood Hits	997	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

HRBL_MOUSE
θ value	1.87187e-05 (rank : 113)	NC score	0.349657 (rank : 262)
Query Neighborhood Hits	395	Target Neighborhood Hits	269	Shared Neighborhood Hits	44
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

POTE8_HUMAN
θ value	1.87187e-05 (rank : 114)	NC score	0.533367 (rank : 145)
Query Neighborhood Hits	395	Target Neighborhood Hits	337	Shared Neighborhood Hits	260
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANR39_HUMAN
θ value	2.44474e-05 (rank : 115)	NC score	0.608723 (rank : 25)
Query Neighborhood Hits	395	Target Neighborhood Hits	285	Shared Neighborhood Hits	260
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB8_HUMAN
θ value	2.44474e-05 (rank : 116)	NC score	0.582283 (rank : 50)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ASB8_MOUSE
θ value	2.44474e-05 (rank : 117)	NC score	0.581716 (rank : 52)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	257
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

BCL3_MOUSE
θ value	2.44474e-05 (rank : 118)	NC score	0.572270 (rank : 76)
Query Neighborhood Hits	395	Target Neighborhood Hits	388	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

INVS_HUMAN
θ value	2.44474e-05 (rank : 119)	NC score	0.568333 (rank : 82)
Query Neighborhood Hits	395	Target Neighborhood Hits	455	Shared Neighborhood Hits	263
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

RN5A_MOUSE
θ value	2.44474e-05 (rank : 120)	NC score	0.500738 (rank : 178)
Query Neighborhood Hits	395	Target Neighborhood Hits	899	Shared Neighborhood Hits	258
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

CYH1_HUMAN
θ value	3.19293e-05 (rank : 121)	NC score	0.171652 (rank : 317)
Query Neighborhood Hits	395	Target Neighborhood Hits	184	Shared Neighborhood Hits	77
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

CYH2_HUMAN
θ value	3.19293e-05 (rank : 122)	NC score	0.169186 (rank : 321)
Query Neighborhood Hits	395	Target Neighborhood Hits	175	Shared Neighborhood Hits	75
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
θ value	3.19293e-05 (rank : 123)	NC score	0.169020 (rank : 322)
Query Neighborhood Hits	395	Target Neighborhood Hits	171	Shared Neighborhood Hits	74
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

EHMT1_HUMAN
θ value	3.19293e-05 (rank : 124)	NC score	0.543904 (rank : 126)
Query Neighborhood Hits	395	Target Neighborhood Hits	417	Shared Neighborhood Hits	263
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

HRBL_HUMAN
θ value	3.19293e-05 (rank : 125)	NC score	0.357297 (rank : 255)
Query Neighborhood Hits	395	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ANKS1_HUMAN
θ value	4.1701e-05 (rank : 126)	NC score	0.533158 (rank : 146)
Query Neighborhood Hits	395	Target Neighborhood Hits	438	Shared Neighborhood Hits	263
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

ANR12_HUMAN
θ value	4.1701e-05 (rank : 127)	NC score	0.486428 (rank : 185)
Query Neighborhood Hits	395	Target Neighborhood Hits	1081	Shared Neighborhood Hits	278
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

CYH1_MOUSE
θ value	4.1701e-05 (rank : 128)	NC score	0.170750 (rank : 319)
Query Neighborhood Hits	395	Target Neighborhood Hits	176	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

CYH4_MOUSE
θ value	4.1701e-05 (rank : 129)	NC score	0.158444 (rank : 329)
Query Neighborhood Hits	395	Target Neighborhood Hits	134	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DAPP1_MOUSE
θ value	4.1701e-05 (rank : 130)	NC score	0.162810 (rank : 326)
Query Neighborhood Hits	395	Target Neighborhood Hits	225	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

TNI3K_MOUSE
θ value	4.1701e-05 (rank : 131)	NC score	0.287840 (rank : 282)
Query Neighborhood Hits	395	Target Neighborhood Hits	1079	Shared Neighborhood Hits	262
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANKY2_HUMAN
θ value	5.44631e-05 (rank : 132)	NC score	0.506175 (rank : 174)
Query Neighborhood Hits	395	Target Neighborhood Hits	306	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR15_HUMAN
θ value	5.44631e-05 (rank : 133)	NC score	0.506872 (rank : 173)
Query Neighborhood Hits	395	Target Neighborhood Hits	478	Shared Neighborhood Hits	265
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ASB14_MOUSE
θ value	5.44631e-05 (rank : 134)	NC score	0.541077 (rank : 132)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	258
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB1_MOUSE
θ value	5.44631e-05 (rank : 135)	NC score	0.524340 (rank : 164)
Query Neighborhood Hits	395	Target Neighborhood Hits	292	Shared Neighborhood Hits	247
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANKS6_HUMAN
θ value	7.1131e-05 (rank : 136)	NC score	0.559041 (rank : 98)
Query Neighborhood Hits	395	Target Neighborhood Hits	411	Shared Neighborhood Hits	262
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR10_MOUSE
θ value	7.1131e-05 (rank : 137)	NC score	0.561120 (rank : 94)
Query Neighborhood Hits	395	Target Neighborhood Hits	273	Shared Neighborhood Hits	246
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR39_MOUSE
θ value	7.1131e-05 (rank : 138)	NC score	0.606400 (rank : 26)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR41_HUMAN
θ value	7.1131e-05 (rank : 139)	NC score	0.558237 (rank : 99)
Query Neighborhood Hits	395	Target Neighborhood Hits	332	Shared Neighborhood Hits	237
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ASB3_HUMAN
θ value	7.1131e-05 (rank : 140)	NC score	0.571621 (rank : 77)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

CYH3_MOUSE
θ value	7.1131e-05 (rank : 141)	NC score	0.160717 (rank : 327)
Query Neighborhood Hits	395	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

DAPK1_HUMAN
θ value	7.1131e-05 (rank : 142)	NC score	0.246606 (rank : 302)
Query Neighborhood Hits	395	Target Neighborhood Hits	1130	Shared Neighborhood Hits	260
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

ANKR1_HUMAN
θ value	9.29e-05 (rank : 143)	NC score	0.579731 (rank : 57)
Query Neighborhood Hits	395	Target Neighborhood Hits	308	Shared Neighborhood Hits	258
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ASB15_HUMAN
θ value	9.29e-05 (rank : 144)	NC score	0.542114 (rank : 129)
Query Neighborhood Hits	395	Target Neighborhood Hits	305	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

CT086_HUMAN
θ value	9.29e-05 (rank : 145)	NC score	0.614033 (rank : 24)
Query Neighborhood Hits	395	Target Neighborhood Hits	277	Shared Neighborhood Hits	251
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

FANK1_MOUSE
θ value	9.29e-05 (rank : 146)	NC score	0.573949 (rank : 73)
Query Neighborhood Hits	395	Target Neighborhood Hits	325	Shared Neighborhood Hits	259
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

NOTC4_MOUSE
θ value	0.000121331 (rank : 147)	NC score	0.309103 (rank : 274)
Query Neighborhood Hits	395	Target Neighborhood Hits	872	Shared Neighborhood Hits	258
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

AN36A_HUMAN
θ value	0.000158464 (rank : 148)	NC score	0.536967 (rank : 139)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	251
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANKR6_HUMAN
θ value	0.000158464 (rank : 149)	NC score	0.590487 (rank : 38)
Query Neighborhood Hits	395	Target Neighborhood Hits	439	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR19_HUMAN
θ value	0.000158464 (rank : 150)	NC score	0.534231 (rank : 143)
Query Neighborhood Hits	395	Target Neighborhood Hits	276	Shared Neighborhood Hits	251
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ANR21_HUMAN
θ value	0.000158464 (rank : 151)	NC score	0.494547 (rank : 180)
Query Neighborhood Hits	395	Target Neighborhood Hits	864	Shared Neighborhood Hits	279
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR23_MOUSE
θ value	0.000158464 (rank : 152)	NC score	0.582806 (rank : 48)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	257
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR42_HUMAN
θ value	0.000158464 (rank : 153)	NC score	0.580646 (rank : 55)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	256
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR46_MOUSE
θ value	0.000158464 (rank : 154)	NC score	0.590646 (rank : 37)
Query Neighborhood Hits	395	Target Neighborhood Hits	274	Shared Neighborhood Hits	248
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CYH4_HUMAN
θ value	0.000158464 (rank : 155)	NC score	0.156075 (rank : 331)
Query Neighborhood Hits	395	Target Neighborhood Hits	135	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

DAPK1_MOUSE
θ value	0.000158464 (rank : 156)	NC score	0.254678 (rank : 299)
Query Neighborhood Hits	395	Target Neighborhood Hits	1138	Shared Neighborhood Hits	261
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

MTPN_HUMAN
θ value	0.000158464 (rank : 157)	NC score	0.592410 (rank : 36)
Query Neighborhood Hits	395	Target Neighborhood Hits	269	Shared Neighborhood Hits	250
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

MTPN_MOUSE
θ value	0.000158464 (rank : 158)	NC score	0.596903 (rank : 31)
Query Neighborhood Hits	395	Target Neighborhood Hits	269	Shared Neighborhood Hits	250
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

NFKB2_MOUSE
θ value	0.000158464 (rank : 159)	NC score	0.467582 (rank : 206)
Query Neighborhood Hits	395	Target Neighborhood Hits	326	Shared Neighborhood Hits	255
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

PKHA1_MOUSE
θ value	0.000158464 (rank : 160)	NC score	0.251597 (rank : 301)
Query Neighborhood Hits	395	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

ANKS6_MOUSE
θ value	0.00020696 (rank : 161)	NC score	0.554396 (rank : 101)
Query Neighborhood Hits	395	Target Neighborhood Hits	435	Shared Neighborhood Hits	262
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

DAPP1_HUMAN
θ value	0.00020696 (rank : 162)	NC score	0.156590 (rank : 330)
Query Neighborhood Hits	395	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

NFKB2_HUMAN
θ value	0.00020696 (rank : 163)	NC score	0.478812 (rank : 192)
Query Neighborhood Hits	395	Target Neighborhood Hits	325	Shared Neighborhood Hits	259
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

RIPK4_HUMAN
θ value	0.00020696 (rank : 164)	NC score	0.353232 (rank : 259)
Query Neighborhood Hits	395	Target Neighborhood Hits	1094	Shared Neighborhood Hits	262
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

USH1G_HUMAN
θ value	0.00020696 (rank : 165)	NC score	0.551936 (rank : 109)
Query Neighborhood Hits	395	Target Neighborhood Hits	267	Shared Neighborhood Hits	248
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	0.00020696 (rank : 166)	NC score	0.552622 (rank : 107)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	248
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANKR7_HUMAN
θ value	0.000270298 (rank : 167)	NC score	0.551358 (rank : 111)
Query Neighborhood Hits	395	Target Neighborhood Hits	286	Shared Neighborhood Hits	254
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR18_HUMAN
θ value	0.000270298 (rank : 168)	NC score	0.431520 (rank : 221)
Query Neighborhood Hits	395	Target Neighborhood Hits	1106	Shared Neighborhood Hits	291
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

CSKI1_MOUSE
θ value	0.000270298 (rank : 169)	NC score	0.532086 (rank : 148)
Query Neighborhood Hits	395	Target Neighborhood Hits	1031	Shared Neighborhood Hits	272
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

FANK1_HUMAN
θ value	0.000270298 (rank : 170)	NC score	0.573430 (rank : 74)
Query Neighborhood Hits	395	Target Neighborhood Hits	326	Shared Neighborhood Hits	259
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANKS1_MOUSE
θ value	0.00035302 (rank : 171)	NC score	0.525614 (rank : 163)
Query Neighborhood Hits	395	Target Neighborhood Hits	453	Shared Neighborhood Hits	265
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ANR26_MOUSE
θ value	0.00035302 (rank : 172)	NC score	0.326689 (rank : 268)
Query Neighborhood Hits	395	Target Neighborhood Hits	1554	Shared Neighborhood Hits	297
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR46_HUMAN
θ value	0.00035302 (rank : 173)	NC score	0.596570 (rank : 33)
Query Neighborhood Hits	395	Target Neighborhood Hits	281	Shared Neighborhood Hits	253
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ASB10_MOUSE
θ value	0.00035302 (rank : 174)	NC score	0.573987 (rank : 72)
Query Neighborhood Hits	395	Target Neighborhood Hits	301	Shared Neighborhood Hits	258
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB11_MOUSE
θ value	0.00035302 (rank : 175)	NC score	0.539659 (rank : 134)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	244
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

IKBE_MOUSE
θ value	0.00035302 (rank : 176)	NC score	0.542518 (rank : 128)
Query Neighborhood Hits	395	Target Neighborhood Hits	308	Shared Neighborhood Hits	255
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

NOTC2_HUMAN
θ value	0.00035302 (rank : 177)	NC score	0.270620 (rank : 288)
Query Neighborhood Hits	395	Target Neighborhood Hits	1113	Shared Neighborhood Hits	262
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OSBL1_MOUSE
θ value	0.00035302 (rank : 178)	NC score	0.430051 (rank : 223)
Query Neighborhood Hits	395	Target Neighborhood Hits	336	Shared Neighborhood Hits	263
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PKHA1_HUMAN
θ value	0.00035302 (rank : 179)	NC score	0.252790 (rank : 300)
Query Neighborhood Hits	395	Target Neighborhood Hits	127	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

ANR11_HUMAN
θ value	0.000461057 (rank : 180)	NC score	0.489289 (rank : 182)
Query Neighborhood Hits	395	Target Neighborhood Hits	1289	Shared Neighborhood Hits	275
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ASB11_HUMAN
θ value	0.000461057 (rank : 181)	NC score	0.534609 (rank : 141)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	245
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CTTB2_HUMAN
θ value	0.000461057 (rank : 182)	NC score	0.501246 (rank : 177)
Query Neighborhood Hits	395	Target Neighborhood Hits	1061	Shared Neighborhood Hits	291
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

IKBE_HUMAN
θ value	0.000461057 (rank : 183)	NC score	0.535253 (rank : 140)
Query Neighborhood Hits	395	Target Neighborhood Hits	288	Shared Neighborhood Hits	252
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

MPP8_HUMAN
θ value	0.000461057 (rank : 184)	NC score	0.440381 (rank : 216)
Query Neighborhood Hits	395	Target Neighborhood Hits	948	Shared Neighborhood Hits	257
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NFKB1_MOUSE
θ value	0.000461057 (rank : 185)	NC score	0.469267 (rank : 205)
Query Neighborhood Hits	395	Target Neighborhood Hits	300	Shared Neighborhood Hits	251
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NOTC2_MOUSE
θ value	0.000461057 (rank : 186)	NC score	0.268297 (rank : 290)
Query Neighborhood Hits	395	Target Neighborhood Hits	1069	Shared Neighborhood Hits	262
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PKHA5_HUMAN
θ value	0.000461057 (rank : 187)	NC score	0.166365 (rank : 324)
Query Neighborhood Hits	395	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

RFXK_HUMAN
θ value	0.000461057 (rank : 188)	NC score	0.550030 (rank : 112)
Query Neighborhood Hits	395	Target Neighborhood Hits	282	Shared Neighborhood Hits	250
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ASB1_HUMAN
θ value	0.000602161 (rank : 189)	NC score	0.529388 (rank : 154)
Query Neighborhood Hits	395	Target Neighborhood Hits	291	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

PP16B_MOUSE
θ value	0.000602161 (rank : 190)	NC score	0.552669 (rank : 105)
Query Neighborhood Hits	395	Target Neighborhood Hits	302	Shared Neighborhood Hits	256
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

TRPA1_MOUSE
θ value	0.000602161 (rank : 191)	NC score	0.547660 (rank : 118)
Query Neighborhood Hits	395	Target Neighborhood Hits	343	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANFY1_HUMAN
θ value	0.000786445 (rank : 192)	NC score	0.509494 (rank : 171)
Query Neighborhood Hits	395	Target Neighborhood Hits	480	Shared Neighborhood Hits	270
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASB10_HUMAN
θ value	0.000786445 (rank : 193)	NC score	0.577651 (rank : 63)
Query Neighborhood Hits	395	Target Neighborhood Hits	291	Shared Neighborhood Hits	257
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASPP2_HUMAN
θ value	0.000786445 (rank : 194)	NC score	0.396181 (rank : 233)
Query Neighborhood Hits	395	Target Neighborhood Hits	1156	Shared Neighborhood Hits	281
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CDN2C_HUMAN
θ value	0.000786445 (rank : 195)	NC score	0.546524 (rank : 120)
Query Neighborhood Hits	395	Target Neighborhood Hits	262	Shared Neighborhood Hits	246
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

DGKH_HUMAN
θ value	0.000786445 (rank : 196)	NC score	0.134517 (rank : 334)
Query Neighborhood Hits	395	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

PP16A_HUMAN
θ value	0.000786445 (rank : 197)	NC score	0.543997 (rank : 125)
Query Neighborhood Hits	395	Target Neighborhood Hits	340	Shared Neighborhood Hits	254
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANKS3_MOUSE
θ value	0.00102713 (rank : 198)	NC score	0.562846 (rank : 92)
Query Neighborhood Hits	395	Target Neighborhood Hits	355	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR49_MOUSE
θ value	0.00102713 (rank : 199)	NC score	0.566428 (rank : 84)
Query Neighborhood Hits	395	Target Neighborhood Hits	285	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ASB13_MOUSE
θ value	0.00102713 (rank : 200)	NC score	0.564847 (rank : 87)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	259
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

DGKD_HUMAN
θ value	0.00102713 (rank : 201)	NC score	0.119925 (rank : 341)
Query Neighborhood Hits	395	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

MIB1_HUMAN
θ value	0.00102713 (rank : 202)	NC score	0.531188 (rank : 150)
Query Neighborhood Hits	395	Target Neighborhood Hits	470	Shared Neighborhood Hits	262
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	0.00102713 (rank : 203)	NC score	0.530898 (rank : 151)
Query Neighborhood Hits	395	Target Neighborhood Hits	471	Shared Neighborhood Hits	261
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MIB2_HUMAN
θ value	0.00102713 (rank : 204)	NC score	0.532443 (rank : 147)
Query Neighborhood Hits	395	Target Neighborhood Hits	438	Shared Neighborhood Hits	259
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

NOTC4_HUMAN
θ value	0.00102713 (rank : 205)	NC score	0.303315 (rank : 277)
Query Neighborhood Hits	395	Target Neighborhood Hits	905	Shared Neighborhood Hits	259
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

SWP70_HUMAN
θ value	0.00102713 (rank : 206)	NC score	0.113274 (rank : 345)
Query Neighborhood Hits	395	Target Neighborhood Hits	973	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ANKR1_MOUSE
θ value	0.00134147 (rank : 207)	NC score	0.577709 (rank : 62)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKS3_HUMAN
θ value	0.00134147 (rank : 208)	NC score	0.554677 (rank : 100)
Query Neighborhood Hits	395	Target Neighborhood Hits	355	Shared Neighborhood Hits	261
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ASB13_HUMAN
θ value	0.00134147 (rank : 209)	NC score	0.564661 (rank : 88)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

IKBB_MOUSE
θ value	0.00134147 (rank : 210)	NC score	0.549915 (rank : 115)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR49_HUMAN
θ value	0.00175202 (rank : 211)	NC score	0.568743 (rank : 81)
Query Neighborhood Hits	395	Target Neighborhood Hits	282	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

CT012_MOUSE
θ value	0.00175202 (rank : 212)	NC score	0.314894 (rank : 272)
Query Neighborhood Hits	395	Target Neighborhood Hits	229	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

MIB2_MOUSE
θ value	0.00175202 (rank : 213)	NC score	0.527271 (rank : 159)
Query Neighborhood Hits	395	Target Neighborhood Hits	409	Shared Neighborhood Hits	256
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

PP16B_HUMAN
θ value	0.00175202 (rank : 214)	NC score	0.552153 (rank : 108)
Query Neighborhood Hits	395	Target Neighborhood Hits	307	Shared Neighborhood Hits	256
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

SWP70_MOUSE
θ value	0.00175202 (rank : 215)	NC score	0.111154 (rank : 346)
Query Neighborhood Hits	395	Target Neighborhood Hits	1097	Shared Neighborhood Hits	111
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ANKY2_MOUSE
θ value	0.00228821 (rank : 216)	NC score	0.482999 (rank : 189)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	243
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

CAPS1_HUMAN
θ value	0.00228821 (rank : 217)	NC score	0.077653 (rank : 371)
Query Neighborhood Hits	395	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CAPS1_MOUSE
θ value	0.00228821 (rank : 218)	NC score	0.079829 (rank : 366)
Query Neighborhood Hits	395	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

NOTC3_HUMAN
θ value	0.00228821 (rank : 219)	NC score	0.275498 (rank : 286)
Query Neighborhood Hits	395	Target Neighborhood Hits	1062	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0.00228821 (rank : 220)	NC score	0.276948 (rank : 285)
Query Neighborhood Hits	395	Target Neighborhood Hits	975	Shared Neighborhood Hits	263
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

OSTF1_MOUSE
θ value	0.00228821 (rank : 221)	NC score	0.432549 (rank : 220)
Query Neighborhood Hits	395	Target Neighborhood Hits	467	Shared Neighborhood Hits	235
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ASB16_HUMAN
θ value	0.00298849 (rank : 222)	NC score	0.548980 (rank : 116)
Query Neighborhood Hits	395	Target Neighborhood Hits	286	Shared Neighborhood Hits	253
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

IASPP_MOUSE
θ value	0.00298849 (rank : 223)	NC score	0.376759 (rank : 247)
Query Neighborhood Hits	395	Target Neighborhood Hits	1024	Shared Neighborhood Hits	254
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NOTC1_HUMAN
θ value	0.00298849 (rank : 224)	NC score	0.266621 (rank : 291)
Query Neighborhood Hits	395	Target Neighborhood Hits	906	Shared Neighborhood Hits	262
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TRPA1_HUMAN
θ value	0.00298849 (rank : 225)	NC score	0.541736 (rank : 130)
Query Neighborhood Hits	395	Target Neighborhood Hits	339	Shared Neighborhood Hits	260
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

IKBB_HUMAN
θ value	0.00390308 (rank : 226)	NC score	0.537185 (rank : 138)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

ILK1_HUMAN
θ value	0.00390308 (rank : 227)	NC score	0.338905 (rank : 265)
Query Neighborhood Hits	395	Target Neighborhood Hits	857	Shared Neighborhood Hits	257
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	0.00390308 (rank : 228)	NC score	0.351151 (rank : 261)
Query Neighborhood Hits	395	Target Neighborhood Hits	848	Shared Neighborhood Hits	257
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	0.00390308 (rank : 229)	NC score	0.336743 (rank : 267)
Query Neighborhood Hits	395	Target Neighborhood Hits	858	Shared Neighborhood Hits	258
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANFY1_MOUSE
θ value	0.00509761 (rank : 230)	NC score	0.508417 (rank : 172)
Query Neighborhood Hits	395	Target Neighborhood Hits	480	Shared Neighborhood Hits	270
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ASPP1_HUMAN
θ value	0.00509761 (rank : 231)	NC score	0.382437 (rank : 239)
Query Neighborhood Hits	395	Target Neighborhood Hits	956	Shared Neighborhood Hits	270
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	0.00509761 (rank : 232)	NC score	0.375463 (rank : 249)
Query Neighborhood Hits	395	Target Neighborhood Hits	1244	Shared Neighborhood Hits	275
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BCOR_HUMAN
θ value	0.00509761 (rank : 233)	NC score	0.465039 (rank : 208)
Query Neighborhood Hits	395	Target Neighborhood Hits	609	Shared Neighborhood Hits	252
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

BCOR_MOUSE
θ value	0.00509761 (rank : 234)	NC score	0.473151 (rank : 199)
Query Neighborhood Hits	395	Target Neighborhood Hits	521	Shared Neighborhood Hits	249
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

IASPP_HUMAN
θ value	0.00509761 (rank : 235)	NC score	0.404517 (rank : 229)
Query Neighborhood Hits	395	Target Neighborhood Hits	688	Shared Neighborhood Hits	247
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

AN13B_MOUSE
θ value	0.00665767 (rank : 236)	NC score	0.377865 (rank : 243)
Query Neighborhood Hits	395	Target Neighborhood Hits	276	Shared Neighborhood Hits	240
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ASB9_MOUSE
θ value	0.00665767 (rank : 237)	NC score	0.526034 (rank : 162)
Query Neighborhood Hits	395	Target Neighborhood Hits	257	Shared Neighborhood Hits	237
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

CDN2C_MOUSE
θ value	0.00665767 (rank : 238)	NC score	0.546770 (rank : 119)
Query Neighborhood Hits	395	Target Neighborhood Hits	270	Shared Neighborhood Hits	248
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

KRIT1_MOUSE
θ value	0.00665767 (rank : 239)	NC score	0.430248 (rank : 222)
Query Neighborhood Hits	395	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

NFKB1_HUMAN
θ value	0.00665767 (rank : 240)	NC score	0.470268 (rank : 204)
Query Neighborhood Hits	395	Target Neighborhood Hits	306	Shared Neighborhood Hits	256
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

OSBL1_HUMAN
θ value	0.00665767 (rank : 241)	NC score	0.438143 (rank : 217)
Query Neighborhood Hits	395	Target Neighborhood Hits	368	Shared Neighborhood Hits	264
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

RASA3_HUMAN
θ value	0.00665767 (rank : 242)	NC score	0.090733 (rank : 354)
Query Neighborhood Hits	395	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RASA3_MOUSE
θ value	0.00665767 (rank : 243)	NC score	0.089069 (rank : 358)
Query Neighborhood Hits	395	Target Neighborhood Hits	144	Shared Neighborhood Hits	37
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

ZDH17_HUMAN
θ value	0.00665767 (rank : 244)	NC score	0.502505 (rank : 175)
Query Neighborhood Hits	395	Target Neighborhood Hits	334	Shared Neighborhood Hits	259
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ZDH17_MOUSE
θ value	0.00665767 (rank : 245)	NC score	0.498722 (rank : 179)
Query Neighborhood Hits	395	Target Neighborhood Hits	328	Shared Neighborhood Hits	256
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

AN13B_HUMAN
θ value	0.00869519 (rank : 246)	NC score	0.376971 (rank : 245)
Query Neighborhood Hits	395	Target Neighborhood Hits	265	Shared Neighborhood Hits	240
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ASZ1_MOUSE
θ value	0.00869519 (rank : 247)	NC score	0.547986 (rank : 117)
Query Neighborhood Hits	395	Target Neighborhood Hits	319	Shared Neighborhood Hits	259
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

FGD1_HUMAN
θ value	0.00869519 (rank : 248)	NC score	0.068676 (rank : 403)
Query Neighborhood Hits	395	Target Neighborhood Hits	367	Shared Neighborhood Hits	44
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

TEX14_MOUSE
θ value	0.00869519 (rank : 249)	NC score	0.269223 (rank : 289)
Query Neighborhood Hits	395	Target Neighborhood Hits	1333	Shared Neighborhood Hits	265
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ASB9_HUMAN
θ value	0.0113563 (rank : 250)	NC score	0.528638 (rank : 158)
Query Neighborhood Hits	395	Target Neighborhood Hits	267	Shared Neighborhood Hits	239
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

FGD3_MOUSE
θ value	0.0113563 (rank : 251)	NC score	0.045138 (rank : 459)
Query Neighborhood Hits	395	Target Neighborhood Hits	257	Shared Neighborhood Hits	27
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

ASB15_MOUSE
θ value	0.0148317 (rank : 252)	NC score	0.529312 (rank : 155)
Query Neighborhood Hits	395	Target Neighborhood Hits	292	Shared Neighborhood Hits	254
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

OSTF1_HUMAN
θ value	0.0148317 (rank : 253)	NC score	0.413225 (rank : 225)
Query Neighborhood Hits	395	Target Neighborhood Hits	466	Shared Neighborhood Hits	235
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

PLEK2_HUMAN
θ value	0.0148317 (rank : 254)	NC score	0.125266 (rank : 336)
Query Neighborhood Hits	395	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

ACBD6_HUMAN
θ value	0.0193708 (rank : 255)	NC score	0.545828 (rank : 123)
Query Neighborhood Hits	395	Target Neighborhood Hits	304	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ACBD6_MOUSE
θ value	0.0193708 (rank : 256)	NC score	0.546468 (rank : 121)
Query Neighborhood Hits	395	Target Neighborhood Hits	305	Shared Neighborhood Hits	256
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

RFXK_MOUSE
θ value	0.0193708 (rank : 257)	NC score	0.539095 (rank : 135)
Query Neighborhood Hits	395	Target Neighborhood Hits	273	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ZDH13_HUMAN
θ value	0.0193708 (rank : 258)	NC score	0.484019 (rank : 188)
Query Neighborhood Hits	395	Target Neighborhood Hits	322	Shared Neighborhood Hits	256
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

AN13C_MOUSE
θ value	0.0252991 (rank : 259)	NC score	0.370309 (rank : 251)
Query Neighborhood Hits	395	Target Neighborhood Hits	242	Shared Neighborhood Hits	224
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN30A_HUMAN
θ value	0.0252991 (rank : 260)	NC score	0.386181 (rank : 238)
Query Neighborhood Hits	395	Target Neighborhood Hits	1119	Shared Neighborhood Hits	282
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR10_HUMAN
θ value	0.0252991 (rank : 261)	NC score	0.562909 (rank : 91)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB5_HUMAN
θ value	0.0252991 (rank : 262)	NC score	0.526280 (rank : 161)
Query Neighborhood Hits	395	Target Neighborhood Hits	283	Shared Neighborhood Hits	251
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB7_HUMAN
θ value	0.0252991 (rank : 263)	NC score	0.559283 (rank : 97)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	258
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	0.0252991 (rank : 264)	NC score	0.559555 (rank : 95)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	258
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

CAPS2_MOUSE
θ value	0.0252991 (rank : 265)	NC score	0.076472 (rank : 374)
Query Neighborhood Hits	395	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

IKBA_MOUSE
θ value	0.0252991 (rank : 266)	NC score	0.519871 (rank : 166)
Query Neighborhood Hits	395	Target Neighborhood Hits	283	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

NOTC1_MOUSE
θ value	0.0252991 (rank : 267)	NC score	0.221725 (rank : 308)
Query Neighborhood Hits	395	Target Neighborhood Hits	916	Shared Neighborhood Hits	245
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PKHA4_HUMAN
θ value	0.0252991 (rank : 268)	NC score	0.170370 (rank : 320)
Query Neighborhood Hits	395	Target Neighborhood Hits	283	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

ZDH13_MOUSE
θ value	0.0252991 (rank : 269)	NC score	0.484975 (rank : 186)
Query Neighborhood Hits	395	Target Neighborhood Hits	329	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

AN13C_HUMAN
θ value	0.0330416 (rank : 270)	NC score	0.376731 (rank : 248)
Query Neighborhood Hits	395	Target Neighborhood Hits	241	Shared Neighborhood Hits	228
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ANR37_HUMAN
θ value	0.0330416 (rank : 271)	NC score	0.534533 (rank : 142)
Query Neighborhood Hits	395	Target Neighborhood Hits	247	Shared Neighborhood Hits	234
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB16_MOUSE
θ value	0.0330416 (rank : 272)	NC score	0.551831 (rank : 110)
Query Neighborhood Hits	395	Target Neighborhood Hits	306	Shared Neighborhood Hits	257
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASZ1_HUMAN
θ value	0.0330416 (rank : 273)	NC score	0.537189 (rank : 137)
Query Neighborhood Hits	395	Target Neighborhood Hits	341	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

IKBA_HUMAN
θ value	0.0330416 (rank : 274)	NC score	0.528978 (rank : 157)
Query Neighborhood Hits	395	Target Neighborhood Hits	280	Shared Neighborhood Hits	256
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

PA2G6_MOUSE
θ value	0.0330416 (rank : 275)	NC score	0.549939 (rank : 114)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	257
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PKHA4_MOUSE
θ value	0.0330416 (rank : 276)	NC score	0.172689 (rank : 316)
Query Neighborhood Hits	395	Target Neighborhood Hits	202	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

POT15_HUMAN
θ value	0.0330416 (rank : 277)	NC score	0.492680 (rank : 181)
Query Neighborhood Hits	395	Target Neighborhood Hits	893	Shared Neighborhood Hits	277
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ABTB2_HUMAN
θ value	0.0431538 (rank : 278)	NC score	0.368437 (rank : 253)
Query Neighborhood Hits	395	Target Neighborhood Hits	391	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

DGKI_HUMAN
θ value	0.0431538 (rank : 279)	NC score	0.265995 (rank : 292)
Query Neighborhood Hits	395	Target Neighborhood Hits	609	Shared Neighborhood Hits	210
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

PA2G6_HUMAN
θ value	0.0431538 (rank : 280)	NC score	0.552697 (rank : 104)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	257
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR26_HUMAN
θ value	0.0563607 (rank : 281)	NC score	0.305807 (rank : 275)
Query Neighborhood Hits	395	Target Neighborhood Hits	1614	Shared Neighborhood Hits	296
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB5_MOUSE
θ value	0.0563607 (rank : 282)	NC score	0.522367 (rank : 165)
Query Neighborhood Hits	395	Target Neighborhood Hits	266	Shared Neighborhood Hits	243
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ANR37_MOUSE
θ value	0.0736092 (rank : 283)	NC score	0.529108 (rank : 156)
Query Neighborhood Hits	395	Target Neighborhood Hits	237	Shared Neighborhood Hits	223
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ASB4_MOUSE
θ value	0.0736092 (rank : 284)	NC score	0.514983 (rank : 168)
Query Neighborhood Hits	395	Target Neighborhood Hits	265	Shared Neighborhood Hits	246
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

FGD1_MOUSE
θ value	0.0736092 (rank : 285)	NC score	0.065375 (rank : 412)
Query Neighborhood Hits	395	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

PLEK2_MOUSE
θ value	0.0736092 (rank : 286)	NC score	0.114574 (rank : 344)
Query Neighborhood Hits	395	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

DGKK_HUMAN
θ value	0.0961366 (rank : 287)	NC score	0.086117 (rank : 360)
Query Neighborhood Hits	395	Target Neighborhood Hits	378	Shared Neighborhood Hits	42
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

GOGA4_HUMAN
θ value	0.0961366 (rank : 288)	NC score	0.041604 (rank : 465)
Query Neighborhood Hits	395	Target Neighborhood Hits	2034	Shared Neighborhood Hits	90
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RASA2_HUMAN
θ value	0.0961366 (rank : 289)	NC score	0.074230 (rank : 378)
Query Neighborhood Hits	395	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

ANR33_HUMAN
θ value	0.125558 (rank : 290)	NC score	0.474911 (rank : 196)
Query Neighborhood Hits	395	Target Neighborhood Hits	215	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CAPS2_HUMAN
θ value	0.125558 (rank : 291)	NC score	0.072579 (rank : 387)
Query Neighborhood Hits	395	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

KRIT1_HUMAN
θ value	0.125558 (rank : 292)	NC score	0.418383 (rank : 224)
Query Neighborhood Hits	395	Target Neighborhood Hits	258	Shared Neighborhood Hits	212
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

POT22_HUMAN
θ value	0.163984 (rank : 293)	NC score	0.457047 (rank : 211)
Query Neighborhood Hits	395	Target Neighborhood Hits	266	Shared Neighborhood Hits	245
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

RASA2_MOUSE
θ value	0.163984 (rank : 294)	NC score	0.075526 (rank : 375)
Query Neighborhood Hits	395	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

ANR22_HUMAN
θ value	0.21417 (rank : 295)	NC score	0.546171 (rank : 122)
Query Neighborhood Hits	395	Target Neighborhood Hits	243	Shared Neighborhood Hits	228
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ASB4_HUMAN
θ value	0.21417 (rank : 296)	NC score	0.514708 (rank : 169)
Query Neighborhood Hits	395	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

GOGA2_MOUSE
θ value	0.21417 (rank : 297)	NC score	0.037938 (rank : 472)
Query Neighborhood Hits	395	Target Neighborhood Hits	944	Shared Neighborhood Hits	57
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

POT14_HUMAN
θ value	0.21417 (rank : 298)	NC score	0.482653 (rank : 190)
Query Neighborhood Hits	395	Target Neighborhood Hits	403	Shared Neighborhood Hits	254
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

ASB6_HUMAN
θ value	0.279714 (rank : 299)	NC score	0.472506 (rank : 201)
Query Neighborhood Hits	395	Target Neighborhood Hits	256	Shared Neighborhood Hits	229
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CLPB_MOUSE
θ value	0.279714 (rank : 300)	NC score	0.440854 (rank : 215)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	233
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

MRE11_HUMAN
θ value	0.279714 (rank : 301)	NC score	0.028041 (rank : 481)
Query Neighborhood Hits	395	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

OSBL8_HUMAN
θ value	0.279714 (rank : 302)	NC score	0.043451 (rank : 460)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

TBCD2_HUMAN
θ value	0.279714 (rank : 303)	NC score	0.050596 (rank : 453)
Query Neighborhood Hits	395	Target Neighborhood Hits	419	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

ZCHC6_MOUSE
θ value	0.279714 (rank : 304)	NC score	0.022985 (rank : 487)
Query Neighborhood Hits	395	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ABTB2_MOUSE
θ value	0.365318 (rank : 305)	NC score	0.356891 (rank : 256)
Query Neighborhood Hits	395	Target Neighborhood Hits	414	Shared Neighborhood Hits	225
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANR25_HUMAN
θ value	0.365318 (rank : 306)	NC score	0.446988 (rank : 214)
Query Neighborhood Hits	395	Target Neighborhood Hits	350	Shared Neighborhood Hits	242
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

ANR33_MOUSE
θ value	0.365318 (rank : 307)	NC score	0.474342 (rank : 197)
Query Neighborhood Hits	395	Target Neighborhood Hits	225	Shared Neighborhood Hits	215
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ASB12_HUMAN
θ value	0.365318 (rank : 308)	NC score	0.530235 (rank : 152)
Query Neighborhood Hits	395	Target Neighborhood Hits	263	Shared Neighborhood Hits	245
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

FGD2_HUMAN
θ value	0.365318 (rank : 309)	NC score	0.039875 (rank : 469)
Query Neighborhood Hits	395	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

TARA_HUMAN
θ value	0.365318 (rank : 310)	NC score	0.063834 (rank : 416)
Query Neighborhood Hits	395	Target Neighborhood Hits	1626	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TARA_MOUSE
θ value	0.365318 (rank : 311)	NC score	0.071437 (rank : 393)
Query Neighborhood Hits	395	Target Neighborhood Hits	1133	Shared Neighborhood Hits	93
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TEX14_HUMAN
θ value	0.365318 (rank : 312)	NC score	0.262611 (rank : 296)
Query Neighborhood Hits	395	Target Neighborhood Hits	1103	Shared Neighborhood Hits	242
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

CCD46_MOUSE
θ value	0.47712 (rank : 313)	NC score	0.039988 (rank : 467)
Query Neighborhood Hits	395	Target Neighborhood Hits	1405	Shared Neighborhood Hits	71
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

DGKZ_HUMAN
θ value	0.47712 (rank : 314)	NC score	0.263295 (rank : 295)
Query Neighborhood Hits	395	Target Neighborhood Hits	551	Shared Neighborhood Hits	209
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

EZH2_HUMAN
θ value	0.47712 (rank : 315)	NC score	0.035757 (rank : 474)
Query Neighborhood Hits	395	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

MRIP_MOUSE
θ value	0.47712 (rank : 316)	NC score	0.073278 (rank : 383)
Query Neighborhood Hits	395	Target Neighborhood Hits	569	Shared Neighborhood Hits	77
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

RHG25_HUMAN
θ value	0.47712 (rank : 317)	NC score	0.125000 (rank : 337)
Query Neighborhood Hits	395	Target Neighborhood Hits	550	Shared Neighborhood Hits	90
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TRPV1_MOUSE
θ value	0.47712 (rank : 318)	NC score	0.142428 (rank : 333)
Query Neighborhood Hits	395	Target Neighborhood Hits	189	Shared Neighborhood Hits	142
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

ANR25_MOUSE
θ value	0.62314 (rank : 319)	NC score	0.432995 (rank : 219)
Query Neighborhood Hits	395	Target Neighborhood Hits	398	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ASB12_MOUSE
θ value	0.62314 (rank : 320)	NC score	0.526641 (rank : 160)
Query Neighborhood Hits	395	Target Neighborhood Hits	261	Shared Neighborhood Hits	243
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB6_MOUSE
θ value	0.62314 (rank : 321)	NC score	0.467227 (rank : 207)
Query Neighborhood Hits	395	Target Neighborhood Hits	264	Shared Neighborhood Hits	234
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

FGD4_HUMAN
θ value	0.62314 (rank : 322)	NC score	0.060503 (rank : 425)
Query Neighborhood Hits	395	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

GAB1_HUMAN
θ value	0.62314 (rank : 323)	NC score	0.079718 (rank : 367)
Query Neighborhood Hits	395	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

GAB1_MOUSE
θ value	0.813845 (rank : 324)	NC score	0.072766 (rank : 386)
Query Neighborhood Hits	395	Target Neighborhood Hits	233	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

ANLN_HUMAN
θ value	1.06291 (rank : 325)	NC score	0.069796 (rank : 399)
Query Neighborhood Hits	395	Target Neighborhood Hits	222	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANR16_HUMAN
θ value	1.06291 (rank : 326)	NC score	0.545299 (rank : 124)
Query Neighborhood Hits	395	Target Neighborhood Hits	286	Shared Neighborhood Hits	255
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR32_HUMAN
θ value	1.06291 (rank : 327)	NC score	0.476926 (rank : 193)
Query Neighborhood Hits	395	Target Neighborhood Hits	270	Shared Neighborhood Hits	242
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

EZH2_MOUSE
θ value	1.06291 (rank : 328)	NC score	0.034774 (rank : 475)
Query Neighborhood Hits	395	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

GOGA5_MOUSE
θ value	1.06291 (rank : 329)	NC score	0.040517 (rank : 466)
Query Neighborhood Hits	395	Target Neighborhood Hits	1434	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TRPV1_HUMAN
θ value	1.06291 (rank : 330)	NC score	0.134141 (rank : 335)
Query Neighborhood Hits	395	Target Neighborhood Hits	184	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV6_MOUSE
θ value	1.06291 (rank : 331)	NC score	0.323343 (rank : 270)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	235
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANLN_MOUSE
θ value	1.38821 (rank : 332)	NC score	0.066790 (rank : 408)
Query Neighborhood Hits	395	Target Neighborhood Hits	297	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

DGKZ_MOUSE
θ value	1.38821 (rank : 333)	NC score	0.240588 (rank : 303)
Query Neighborhood Hits	395	Target Neighborhood Hits	542	Shared Neighborhood Hits	193
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

FGD4_MOUSE
θ value	1.38821 (rank : 334)	NC score	0.071600 (rank : 392)
Query Neighborhood Hits	395	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

ANR43_HUMAN
θ value	1.81305 (rank : 335)	NC score	0.394666 (rank : 234)
Query Neighborhood Hits	395	Target Neighborhood Hits	209	Shared Neighborhood Hits	198
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

DJC17_MOUSE
θ value	1.81305 (rank : 336)	NC score	0.009887 (rank : 498)
Query Neighborhood Hits	395	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WT4, Q8C5R1	Gene names	Dnajc17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

EEA1_HUMAN
θ value	1.81305 (rank : 337)	NC score	0.045288 (rank : 458)
Query Neighborhood Hits	395	Target Neighborhood Hits	1796	Shared Neighborhood Hits	94
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GCC2_HUMAN
θ value	1.81305 (rank : 338)	NC score	0.039741 (rank : 471)
Query Neighborhood Hits	395	Target Neighborhood Hits	1558	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

KI13A_MOUSE
θ value	1.81305 (rank : 339)	NC score	0.005208 (rank : 499)
Query Neighborhood Hits	395	Target Neighborhood Hits	395	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

OSBL3_HUMAN
θ value	1.81305 (rank : 340)	NC score	0.064954 (rank : 413)
Query Neighborhood Hits	395	Target Neighborhood Hits	93	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKHB2_HUMAN
θ value	1.81305 (rank : 341)	NC score	0.064287 (rank : 414)
Query Neighborhood Hits	395	Target Neighborhood Hits	54	Shared Neighborhood Hits	34
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

RBP24_HUMAN
θ value	1.81305 (rank : 342)	NC score	0.039804 (rank : 470)
Query Neighborhood Hits	395	Target Neighborhood Hits	1559	Shared Neighborhood Hits	78
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

ZCHC6_HUMAN
θ value	1.81305 (rank : 343)	NC score	0.019525 (rank : 493)
Query Neighborhood Hits	395	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

ANR32_MOUSE
θ value	2.36792 (rank : 344)	NC score	0.472187 (rank : 202)
Query Neighborhood Hits	395	Target Neighborhood Hits	285	Shared Neighborhood Hits	242
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ARBK1_HUMAN
θ value	2.36792 (rank : 345)	NC score	0.004510 (rank : 500)
Query Neighborhood Hits	395	Target Neighborhood Hits	859	Shared Neighborhood Hits	23
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

CLPB_HUMAN
θ value	2.36792 (rank : 346)	NC score	0.381189 (rank : 240)
Query Neighborhood Hits	395	Target Neighborhood Hits	265	Shared Neighborhood Hits	219
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

MYH9_HUMAN
θ value	2.36792 (rank : 347)	NC score	0.026962 (rank : 484)
Query Neighborhood Hits	395	Target Neighborhood Hits	1762	Shared Neighborhood Hits	87
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ANR43_MOUSE
θ value	3.0926 (rank : 348)	NC score	0.391674 (rank : 237)
Query Neighborhood Hits	395	Target Neighborhood Hits	214	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CNKR1_HUMAN
θ value	3.0926 (rank : 349)	NC score	0.097044 (rank : 351)
Query Neighborhood Hits	395	Target Neighborhood Hits	154	Shared Neighborhood Hits	42
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

FGD3_HUMAN
θ value	3.0926 (rank : 350)	NC score	0.034385 (rank : 476)
Query Neighborhood Hits	395	Target Neighborhood Hits	249	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

MRE11_MOUSE
θ value	3.0926 (rank : 351)	NC score	0.024065 (rank : 486)
Query Neighborhood Hits	395	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

MYH9_MOUSE
θ value	3.0926 (rank : 352)	NC score	0.027016 (rank : 483)
Query Neighborhood Hits	395	Target Neighborhood Hits	1829	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

OSBL3_MOUSE
θ value	3.0926 (rank : 353)	NC score	0.063994 (rank : 415)
Query Neighborhood Hits	395	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PHLB2_MOUSE
θ value	3.0926 (rank : 354)	NC score	0.065437 (rank : 411)
Query Neighborhood Hits	395	Target Neighborhood Hits	1016	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

SEM3E_MOUSE
θ value	3.0926 (rank : 355)	NC score	0.000271 (rank : 505)
Query Neighborhood Hits	395	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).

TRPV5_MOUSE
θ value	3.0926 (rank : 356)	NC score	0.294359 (rank : 279)
Query Neighborhood Hits	395	Target Neighborhood Hits	278	Shared Neighborhood Hits	231
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

CD2A1_HUMAN
θ value	4.03905 (rank : 357)	NC score	0.400106 (rank : 232)
Query Neighborhood Hits	395	Target Neighborhood Hits	196	Shared Neighborhood Hits	181
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

DYHC_HUMAN
θ value	4.03905 (rank : 358)	NC score	0.020097 (rank : 491)
Query Neighborhood Hits	395	Target Neighborhood Hits	733	Shared Neighborhood Hits	42
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	4.03905 (rank : 359)	NC score	0.020091 (rank : 492)
Query Neighborhood Hits	395	Target Neighborhood Hits	729	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

FGD2_MOUSE
θ value	4.03905 (rank : 360)	NC score	0.041706 (rank : 464)
Query Neighborhood Hits	395	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

GAB2_MOUSE
θ value	4.03905 (rank : 361)	NC score	0.074232 (rank : 377)
Query Neighborhood Hits	395	Target Neighborhood Hits	220	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

MYO10_HUMAN
θ value	4.03905 (rank : 362)	NC score	0.056867 (rank : 434)
Query Neighborhood Hits	395	Target Neighborhood Hits	920	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

SMC3_HUMAN
θ value	4.03905 (rank : 363)	NC score	0.028162 (rank : 480)
Query Neighborhood Hits	395	Target Neighborhood Hits	1186	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	4.03905 (rank : 364)	NC score	0.028236 (rank : 479)
Query Neighborhood Hits	395	Target Neighborhood Hits	1187	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

ANR38_MOUSE
θ value	5.27518 (rank : 365)	NC score	0.393178 (rank : 236)
Query Neighborhood Hits	395	Target Neighborhood Hits	512	Shared Neighborhood Hits	236
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

DAAM1_HUMAN
θ value	5.27518 (rank : 366)	NC score	0.012819 (rank : 496)
Query Neighborhood Hits	395	Target Neighborhood Hits	483	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

FARP1_HUMAN
θ value	5.27518 (rank : 367)	NC score	0.047572 (rank : 457)
Query Neighborhood Hits	395	Target Neighborhood Hits	241	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

KIF1A_MOUSE
θ value	5.27518 (rank : 368)	NC score	0.003309 (rank : 502)
Query Neighborhood Hits	395	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

MRIP_HUMAN
θ value	5.27518 (rank : 369)	NC score	0.065775 (rank : 410)
Query Neighborhood Hits	395	Target Neighborhood Hits	578	Shared Neighborhood Hits	76
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PHLB2_HUMAN
θ value	5.27518 (rank : 370)	NC score	0.060472 (rank : 426)
Query Neighborhood Hits	395	Target Neighborhood Hits	964	Shared Neighborhood Hits	80
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

PLEC1_HUMAN
θ value	5.27518 (rank : 371)	NC score	0.022045 (rank : 489)
Query Neighborhood Hits	395	Target Neighborhood Hits	1326	Shared Neighborhood Hits	70
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

APLP2_HUMAN
θ value	6.88961 (rank : 372)	NC score	0.004294 (rank : 501)
Query Neighborhood Hits	395	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

ARBK1_MOUSE
θ value	6.88961 (rank : 373)	NC score	0.003067 (rank : 503)
Query Neighborhood Hits	395	Target Neighborhood Hits	849	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

GAB2_HUMAN
θ value	6.88961 (rank : 374)	NC score	0.073784 (rank : 382)
Query Neighborhood Hits	395	Target Neighborhood Hits	188	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

GFAP_MOUSE
θ value	6.88961 (rank : 375)	NC score	0.012931 (rank : 495)
Query Neighborhood Hits	395	Target Neighborhood Hits	725	Shared Neighborhood Hits	53
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

GNAS1_HUMAN
θ value	6.88961 (rank : 376)	NC score	0.001408 (rank : 504)
Query Neighborhood Hits	395	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

MYH11_MOUSE
θ value	6.88961 (rank : 377)	NC score	0.027914 (rank : 482)
Query Neighborhood Hits	395	Target Neighborhood Hits	1777	Shared Neighborhood Hits	89
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

OSBL6_HUMAN
θ value	6.88961 (rank : 378)	NC score	0.042899 (rank : 462)
Query Neighborhood Hits	395	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	6.88961 (rank : 379)	NC score	0.042893 (rank : 463)
Query Neighborhood Hits	395	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL7_HUMAN
θ value	6.88961 (rank : 380)	NC score	0.042971 (rank : 461)
Query Neighborhood Hits	395	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

PKHB2_MOUSE
θ value	6.88961 (rank : 381)	NC score	0.072121 (rank : 390)
Query Neighborhood Hits	395	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

ANKY1_HUMAN
θ value	8.99809 (rank : 382)	NC score	0.325397 (rank : 269)
Query Neighborhood Hits	395	Target Neighborhood Hits	248	Shared Neighborhood Hits	195
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ANKZ1_HUMAN
θ value	8.99809 (rank : 383)	NC score	0.196874 (rank : 312)
Query Neighborhood Hits	395	Target Neighborhood Hits	236	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANKZ1_MOUSE
θ value	8.99809 (rank : 384)	NC score	0.212566 (rank : 309)
Query Neighborhood Hits	395	Target Neighborhood Hits	208	Shared Neighborhood Hits	145
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

ANR38_HUMAN
θ value	8.99809 (rank : 385)	NC score	0.411524 (rank : 226)
Query Neighborhood Hits	395	Target Neighborhood Hits	443	Shared Neighborhood Hits	238
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

C43BP_MOUSE
θ value	8.99809 (rank : 386)	NC score	0.056869 (rank : 433)
Query Neighborhood Hits	395	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CP250_MOUSE
θ value	8.99809 (rank : 387)	NC score	0.039896 (rank : 468)
Query Neighborhood Hits	395	Target Neighborhood Hits	1583	Shared Neighborhood Hits	85
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

KTN1_MOUSE
θ value	8.99809 (rank : 388)	NC score	0.035909 (rank : 473)
Query Neighborhood Hits	395	Target Neighborhood Hits	1324	Shared Neighborhood Hits	69
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYH14_MOUSE
θ value	8.99809 (rank : 389)	NC score	0.022824 (rank : 488)
Query Neighborhood Hits	395	Target Neighborhood Hits	1225	Shared Neighborhood Hits	77
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PLD1_HUMAN
θ value	8.99809 (rank : 390)	NC score	0.012459 (rank : 497)
Query Neighborhood Hits	395	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

PLD1_MOUSE
θ value	8.99809 (rank : 391)	NC score	0.013097 (rank : 494)
Query Neighborhood Hits	395	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

SETB2_HUMAN
θ value	8.99809 (rank : 392)	NC score	0.032717 (rank : 477)
Query Neighborhood Hits	395	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SKIL_MOUSE
θ value	8.99809 (rank : 393)	NC score	0.025085 (rank : 485)
Query Neighborhood Hits	395	Target Neighborhood Hits	719	Shared Neighborhood Hits	47
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

SM1L2_HUMAN
θ value	8.99809 (rank : 394)	NC score	0.031089 (rank : 478)
Query Neighborhood Hits	395	Target Neighborhood Hits	1019	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SPTB2_MOUSE
θ value	8.99809 (rank : 395)	NC score	0.020867 (rank : 490)
Query Neighborhood Hits	395	Target Neighborhood Hits	770	Shared Neighborhood Hits	59
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

3BP1_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.068085 (rank : 405)
Query Neighborhood Hits	395	Target Neighborhood Hits	376	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP1_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.066084 (rank : 409)
Query Neighborhood Hits	395	Target Neighborhood Hits	238	Shared Neighborhood Hits	23
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

3BP2_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.077624 (rank : 372)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	42
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

3BP2_MOUSE
θ value	θ > 10 (rank : 399)	NC score	0.072894 (rank : 385)
Query Neighborhood Hits	395	Target Neighborhood Hits	142	Shared Neighborhood Hits	39
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ABR_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.074028 (rank : 380)
Query Neighborhood Hits	395	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ABTB1_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.153516 (rank : 332)
Query Neighborhood Hits	395	Target Neighborhood Hits	325	Shared Neighborhood Hits	151
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

ABTB1_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.177481 (rank : 314)
Query Neighborhood Hits	395	Target Neighborhood Hits	349	Shared Neighborhood Hits	166
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

AN13A_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.304879 (rank : 276)
Query Neighborhood Hits	395	Target Neighborhood Hits	243	Shared Neighborhood Hits	204
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

AN13A_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.288245 (rank : 281)
Query Neighborhood Hits	395	Target Neighborhood Hits	226	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

ANKF1_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.082776 (rank : 363)
Query Neighborhood Hits	395	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANKR9_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.159124 (rank : 328)
Query Neighborhood Hits	395	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	θ > 10 (rank : 407)	NC score	0.195316 (rank : 313)
Query Neighborhood Hits	395	Target Neighborhood Hits	120	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANR40_HUMAN
θ value	θ > 10 (rank : 408)	NC score	0.349187 (rank : 263)
Query Neighborhood Hits	395	Target Neighborhood Hits	224	Shared Neighborhood Hits	192
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
θ value	θ > 10 (rank : 409)	NC score	0.345661 (rank : 264)
Query Neighborhood Hits	395	Target Neighborhood Hits	228	Shared Neighborhood Hits	195
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR45_HUMAN
θ value	θ > 10 (rank : 410)	NC score	0.377710 (rank : 244)
Query Neighborhood Hits	395	Target Neighborhood Hits	201	Shared Neighborhood Hits	175
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
θ value	θ > 10 (rank : 411)	NC score	0.405455 (rank : 227)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	180
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB14_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.319284 (rank : 271)
Query Neighborhood Hits	395	Target Neighborhood Hits	187	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

BAT4_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.170893 (rank : 318)
Query Neighborhood Hits	395	Target Neighborhood Hits	157	Shared Neighborhood Hits	102
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BAT4_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.174404 (rank : 315)
Query Neighborhood Hits	395	Target Neighborhood Hits	171	Shared Neighborhood Hits	112
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

BCR_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.074344 (rank : 376)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

BIG1_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.059469 (rank : 428)
Query Neighborhood Hits	395	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

BIG2_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.060713 (rank : 423)
Query Neighborhood Hits	395	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

C43BP_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.050097 (rank : 456)
Query Neighborhood Hits	395	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CD2A1_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.448111 (rank : 213)
Query Neighborhood Hits	395	Target Neighborhood Hits	206	Shared Neighborhood Hits	192
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CDN2B_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.393468 (rank : 235)
Query Neighborhood Hits	395	Target Neighborhood Hits	196	Shared Neighborhood Hits	187
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CDN2B_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.400792 (rank : 231)
Query Neighborhood Hits	395	Target Neighborhood Hits	201	Shared Neighborhood Hits	189
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CE005_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.053581 (rank : 445)
Query Neighborhood Hits	395	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.051463 (rank : 449)
Query Neighborhood Hits	395	Target Neighborhood Hits	238	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

CHIN_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.069113 (rank : 400)
Query Neighborhood Hits	395	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.069064 (rank : 401)
Query Neighborhood Hits	395	Target Neighborhood Hits	229	Shared Neighborhood Hits	13
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.068844 (rank : 402)
Query Neighborhood Hits	395	Target Neighborhood Hits	220	Shared Neighborhood Hits	13
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.071417 (rank : 394)
Query Neighborhood Hits	395	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CLR59_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.163248 (rank : 325)
Query Neighborhood Hits	395	Target Neighborhood Hits	163	Shared Neighborhood Hits	133
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

CMTA1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.109088 (rank : 347)
Query Neighborhood Hits	395	Target Neighborhood Hits	217	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.089135 (rank : 357)
Query Neighborhood Hits	395	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.084467 (rank : 362)
Query Neighborhood Hits	395	Target Neighborhood Hits	216	Shared Neighborhood Hits	75
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CNKR2_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.072160 (rank : 389)
Query Neighborhood Hits	395	Target Neighborhood Hits	197	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.072362 (rank : 388)
Query Neighborhood Hits	395	Target Neighborhood Hits	197	Shared Neighborhood Hits	51
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CT012_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.259715 (rank : 298)
Query Neighborhood Hits	395	Target Neighborhood Hits	205	Shared Neighborhood Hits	162
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CU081_HUMAN
θ value	θ > 10 (rank : 435)	NC score	0.092177 (rank : 352)
Query Neighborhood Hits	395	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

FBX8_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.054903 (rank : 441)
Query Neighborhood Hits	395	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

FBX8_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.055144 (rank : 438)
Query Neighborhood Hits	395	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

FNBP2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.063195 (rank : 418)
Query Neighborhood Hits	395	Target Neighborhood Hits	432	Shared Neighborhood Hits	36
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

GBF1_HUMAN
θ value	θ > 10 (rank : 439)	NC score	0.060317 (rank : 427)
Query Neighborhood Hits	395	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GLSK_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.282094 (rank : 284)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	176
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GLSL_HUMAN
θ value	θ > 10 (rank : 441)	NC score	0.313598 (rank : 273)
Query Neighborhood Hits	395	Target Neighborhood Hits	211	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
θ value	θ > 10 (rank : 442)	NC score	0.302053 (rank : 278)
Query Neighborhood Hits	395	Target Neighborhood Hits	212	Shared Neighborhood Hits	187
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GMIP_HUMAN
θ value	θ > 10 (rank : 443)	NC score	0.073229 (rank : 384)
Query Neighborhood Hits	395	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_MOUSE
θ value	θ > 10 (rank : 444)	NC score	0.078118 (rank : 370)
Query Neighborhood Hits	395	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GRLF1_HUMAN
θ value	θ > 10 (rank : 445)	NC score	0.073808 (rank : 381)
Query Neighborhood Hits	395	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

IKBL_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.202024 (rank : 310)
Query Neighborhood Hits	395	Target Neighborhood Hits	168	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.198649 (rank : 311)
Query Neighborhood Hits	395	Target Neighborhood Hits	196	Shared Neighborhood Hits	143
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IQEC1_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.055140 (rank : 439)
Query Neighborhood Hits	395	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

IQEC1_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.054249 (rank : 443)
Query Neighborhood Hits	395	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC2_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.050600 (rank : 452)
Query Neighborhood Hits	395	Target Neighborhood Hits	403	Shared Neighborhood Hits	25
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.050859 (rank : 451)
Query Neighborhood Hits	395	Target Neighborhood Hits	417	Shared Neighborhood Hits	26
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC3_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.053594 (rank : 444)
Query Neighborhood Hits	395	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

IQEC3_MOUSE
θ value	θ > 10 (rank : 453)	NC score	0.058026 (rank : 431)
Query Neighborhood Hits	395	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

NUD12_HUMAN
θ value	θ > 10 (rank : 454)	NC score	0.336777 (rank : 266)
Query Neighborhood Hits	395	Target Neighborhood Hits	222	Shared Neighborhood Hits	188
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

NUD12_MOUSE
θ value	θ > 10 (rank : 455)	NC score	0.356516 (rank : 258)
Query Neighborhood Hits	395	Target Neighborhood Hits	243	Shared Neighborhood Hits	210
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

OSBL9_HUMAN
θ value	θ > 10 (rank : 456)	NC score	0.069974 (rank : 398)
Query Neighborhood Hits	395	Target Neighborhood Hits	138	Shared Neighborhood Hits	51
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSBP1_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.090906 (rank : 353)
Query Neighborhood Hits	395	Target Neighborhood Hits	180	Shared Neighborhood Hits	64
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBP2_HUMAN
θ value	θ > 10 (rank : 458)	NC score	0.062206 (rank : 420)
Query Neighborhood Hits	395	Target Neighborhood Hits	154	Shared Neighborhood Hits	51
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	θ > 10 (rank : 459)	NC score	0.055098 (rank : 440)
Query Neighborhood Hits	395	Target Neighborhood Hits	150	Shared Neighborhood Hits	50
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

PHLB1_HUMAN
θ value	θ > 10 (rank : 460)	NC score	0.054320 (rank : 442)
Query Neighborhood Hits	395	Target Neighborhood Hits	1038	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PHLB1_MOUSE
θ value	θ > 10 (rank : 461)	NC score	0.056655 (rank : 436)
Query Neighborhood Hits	395	Target Neighborhood Hits	678	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PLEK_HUMAN
θ value	θ > 10 (rank : 462)	NC score	0.114642 (rank : 343)
Query Neighborhood Hits	395	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK_MOUSE
θ value	θ > 10 (rank : 463)	NC score	0.108064 (rank : 348)
Query Neighborhood Hits	395	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

PSD3_HUMAN
θ value	θ > 10 (rank : 464)	NC score	0.071318 (rank : 395)
Query Neighborhood Hits	395	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

PSD4_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.056805 (rank : 435)
Query Neighborhood Hits	395	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PSD4_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.055868 (rank : 437)
Query Neighborhood Hits	395	Target Neighborhood Hits	78	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

RASA1_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.050177 (rank : 455)
Query Neighborhood Hits	395	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

RBP1_HUMAN
θ value	θ > 10 (rank : 468)	NC score	0.087337 (rank : 359)
Query Neighborhood Hits	395	Target Neighborhood Hits	521	Shared Neighborhood Hits	48
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RBP1_MOUSE
θ value	θ > 10 (rank : 469)	NC score	0.089627 (rank : 355)
Query Neighborhood Hits	395	Target Neighborhood Hits	493	Shared Neighborhood Hits	49
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RGAP1_HUMAN
θ value	θ > 10 (rank : 470)	NC score	0.079886 (rank : 365)
Query Neighborhood Hits	395	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	θ > 10 (rank : 471)	NC score	0.080864 (rank : 364)
Query Neighborhood Hits	395	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RHG01_HUMAN
θ value	θ > 10 (rank : 472)	NC score	0.059305 (rank : 430)
Query Neighborhood Hits	395	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG04_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.060509 (rank : 424)
Query Neighborhood Hits	395	Target Neighborhood Hits	307	Shared Neighborhood Hits	22
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG05_HUMAN
θ value	θ > 10 (rank : 474)	NC score	0.071710 (rank : 391)
Query Neighborhood Hits	395	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG05_MOUSE
θ value	θ > 10 (rank : 475)	NC score	0.071168 (rank : 396)
Query Neighborhood Hits	395	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG06_HUMAN
θ value	θ > 10 (rank : 476)	NC score	0.068330 (rank : 404)
Query Neighborhood Hits	395	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
θ value	θ > 10 (rank : 477)	NC score	0.068047 (rank : 406)
Query Neighborhood Hits	395	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG07_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.050458 (rank : 454)
Query Neighborhood Hits	395	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG08_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.051392 (rank : 450)
Query Neighborhood Hits	395	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.051807 (rank : 448)
Query Neighborhood Hits	395	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG09_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.089489 (rank : 356)
Query Neighborhood Hits	395	Target Neighborhood Hits	186	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG12_HUMAN
θ value	θ > 10 (rank : 482)	NC score	0.074090 (rank : 379)
Query Neighborhood Hits	395	Target Neighborhood Hits	190	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
θ value	θ > 10 (rank : 483)	NC score	0.077309 (rank : 373)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG18_HUMAN
θ value	θ > 10 (rank : 484)	NC score	0.070503 (rank : 397)
Query Neighborhood Hits	395	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG18_MOUSE
θ value	θ > 10 (rank : 485)	NC score	0.066946 (rank : 407)
Query Neighborhood Hits	395	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG25_MOUSE
θ value	θ > 10 (rank : 486)	NC score	0.123576 (rank : 339)
Query Neighborhood Hits	395	Target Neighborhood Hits	492	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RSNL2_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.123960 (rank : 338)
Query Neighborhood Hits	395	Target Neighborhood Hits	136	Shared Neighborhood Hits	106
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RSNL2_MOUSE
θ value	θ > 10 (rank : 488)	NC score	0.104569 (rank : 350)
Query Neighborhood Hits	395	Target Neighborhood Hits	129	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

SNCAP_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.460668 (rank : 209)
Query Neighborhood Hits	395	Target Neighborhood Hits	313	Shared Neighborhood Hits	224
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

SRGP1_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.061436 (rank : 422)
Query Neighborhood Hits	395	Target Neighborhood Hits	390	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

SRGP2_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.062281 (rank : 419)
Query Neighborhood Hits	395	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

SRGP2_MOUSE
θ value	θ > 10 (rank : 492)	NC score	0.061911 (rank : 421)
Query Neighborhood Hits	395	Target Neighborhood Hits	324	Shared Neighborhood Hits	33
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

TAGAP_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.063215 (rank : 417)
Query Neighborhood Hits	395	Target Neighborhood Hits	82	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TAGAP_MOUSE
θ value	θ > 10 (rank : 494)	NC score	0.057313 (rank : 432)
Query Neighborhood Hits	395	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TCGAP_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.085518 (rank : 361)
Query Neighborhood Hits	395	Target Neighborhood Hits	872	Shared Neighborhood Hits	37
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	θ > 10 (rank : 496)	NC score	0.078551 (rank : 369)
Query Neighborhood Hits	395	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRPC6_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.053013 (rank : 447)
Query Neighborhood Hits	395	Target Neighborhood Hits	171	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPV2_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.106326 (rank : 349)
Query Neighborhood Hits	395	Target Neighborhood Hits	130	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 499)	NC score	0.079575 (rank : 368)
Query Neighborhood Hits	395	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV3_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.121037 (rank : 340)
Query Neighborhood Hits	395	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.119828 (rank : 342)
Query Neighborhood Hits	395	Target Neighborhood Hits	188	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.059431 (rank : 429)
Query Neighborhood Hits	395	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.053441 (rank : 446)
Query Neighborhood Hits	395	Target Neighborhood Hits	117	Shared Neighborhood Hits	68
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV5_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.265975 (rank : 293)
Query Neighborhood Hits	395	Target Neighborhood Hits	261	Shared Neighborhood Hits	207
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV6_HUMAN
θ value	θ > 10 (rank : 505)	NC score	0.260302 (rank : 297)
Query Neighborhood Hits	395	Target Neighborhood Hits	262	Shared Neighborhood Hits	209
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

Hits sorted by NC score

CENB5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	395	Target Neighborhood Hits	395	Shared Neighborhood Hits	395
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CENB2_HUMAN
NC score	0.975300 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	395	Target Neighborhood Hits	425	Shared Neighborhood Hits	332
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB1_HUMAN
NC score	0.967481 (rank : 3)	θ value	6.40027e-139 (rank : 3)
Query Neighborhood Hits	395	Target Neighborhood Hits	383	Shared Neighborhood Hits	335
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DDFL1_MOUSE
NC score	0.830829 (rank : 4)	θ value	5.38352e-45 (rank : 6)
Query Neighborhood Hits	395	Target Neighborhood Hits	324	Shared Neighborhood Hits	275
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DDFL1_HUMAN
NC score	0.806429 (rank : 5)	θ value	1.41672e-45 (rank : 5)
Query Neighborhood Hits	395	Target Neighborhood Hits	353	Shared Neighborhood Hits	264
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDEF2_HUMAN
NC score	0.786941 (rank : 6)	θ value	2.85459e-46 (rank : 4)
Query Neighborhood Hits	395	Target Neighborhood Hits	599	Shared Neighborhood Hits	273
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
NC score	0.781526 (rank : 7)	θ value	1.19932e-44 (rank : 7)
Query Neighborhood Hits	395	Target Neighborhood Hits	625	Shared Neighborhood Hits	273
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF1_MOUSE
NC score	0.738364 (rank : 8)	θ value	6.58091e-43 (rank : 8)
Query Neighborhood Hits	395	Target Neighborhood Hits	592	Shared Neighborhood Hits	235
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GIT2_MOUSE
NC score	0.731166 (rank : 9)	θ value	5.8054e-15 (rank : 36)
Query Neighborhood Hits	395	Target Neighborhood Hits	323	Shared Neighborhood Hits	260
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

CENG1_MOUSE
NC score	0.720326 (rank : 10)	θ value	9.52487e-34 (rank : 11)
Query Neighborhood Hits	395	Target Neighborhood Hits	531	Shared Neighborhood Hits	254
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

GIT1_MOUSE
NC score	0.717046 (rank : 11)	θ value	2.60593e-15 (rank : 34)
Query Neighborhood Hits	395	Target Neighborhood Hits	341	Shared Neighborhood Hits	264
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GIT1_HUMAN
NC score	0.716642 (rank : 12)	θ value	2.60593e-15 (rank : 33)
Query Neighborhood Hits	395	Target Neighborhood Hits	336	Shared Neighborhood Hits	263
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

CENG1_HUMAN
NC score	0.713684 (rank : 13)	θ value	2.77131e-33 (rank : 13)
Query Neighborhood Hits	395	Target Neighborhood Hits	544	Shared Neighborhood Hits	256
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

GIT2_HUMAN
NC score	0.710304 (rank : 14)	θ value	5.8054e-15 (rank : 35)
Query Neighborhood Hits	395	Target Neighborhood Hits	381	Shared Neighborhood Hits	258
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

CENG3_MOUSE
NC score	0.697283 (rank : 15)	θ value	5.584e-34 (rank : 10)
Query Neighborhood Hits	395	Target Neighborhood Hits	467	Shared Neighborhood Hits	244
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_HUMAN
NC score	0.697021 (rank : 16)	θ value	1.24399e-33 (rank : 12)
Query Neighborhood Hits	395	Target Neighborhood Hits	455	Shared Neighborhood Hits	244
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG2_MOUSE
NC score	0.696783 (rank : 17)	θ value	2.77131e-33 (rank : 14)
Query Neighborhood Hits	395	Target Neighborhood Hits	463	Shared Neighborhood Hits	266
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG2_HUMAN
NC score	0.695670 (rank : 18)	θ value	5.584e-34 (rank : 9)
Query Neighborhood Hits	395	Target Neighborhood Hits	471	Shared Neighborhood Hits	267
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENA1_HUMAN
NC score	0.637848 (rank : 19)	θ value	2.27762e-19 (rank : 26)
Query Neighborhood Hits	395	Target Neighborhood Hits	87	Shared Neighborhood Hits	78
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

SMAP1_MOUSE
NC score	0.625333 (rank : 20)	θ value	1.09232e-21 (rank : 16)
Query Neighborhood Hits	395	Target Neighborhood Hits	120	Shared Neighborhood Hits	40
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
NC score	0.623539 (rank : 21)	θ value	3.17815e-21 (rank : 19)
Query Neighborhood Hits	395	Target Neighborhood Hits	74	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
NC score	0.622421 (rank : 22)	θ value	3.17815e-21 (rank : 20)
Query Neighborhood Hits	395	Target Neighborhood Hits	70	Shared Neighborhood Hits	40
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SMAP1_HUMAN
NC score	0.622300 (rank : 23)	θ value	7.0802e-21 (rank : 21)
Query Neighborhood Hits	395	Target Neighborhood Hits	98	Shared Neighborhood Hits	38
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

CT086_HUMAN
NC score	0.614033 (rank : 24)	θ value	9.29e-05 (rank : 145)
Query Neighborhood Hits	395	Target Neighborhood Hits	277	Shared Neighborhood Hits	251
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR39_HUMAN
NC score	0.608723 (rank : 25)	θ value	2.44474e-05 (rank : 115)
Query Neighborhood Hits	395	Target Neighborhood Hits	285	Shared Neighborhood Hits	260
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR39_MOUSE
NC score	0.606400 (rank : 26)	θ value	7.1131e-05 (rank : 138)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	258
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

CENA2_HUMAN
NC score	0.603510 (rank : 27)	θ value	6.85773e-16 (rank : 32)
Query Neighborhood Hits	395	Target Neighborhood Hits	83	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENA2_MOUSE
NC score	0.600354 (rank : 28)	θ value	1.80466e-16 (rank : 31)
Query Neighborhood Hits	395	Target Neighborhood Hits	68	Shared Neighborhood Hits	58
SwissProt Accessions	Q8R2V5	Gene names	Centa2
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 2.

PSD10_HUMAN
NC score	0.598479 (rank : 29)	θ value	4.92598e-06 (rank : 97)
Query Neighborhood Hits	395	Target Neighborhood Hits	301	Shared Neighborhood Hits	260
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

GABP3_MOUSE
NC score	0.596956 (rank : 30)	θ value	4.92598e-06 (rank : 96)
Query Neighborhood Hits	395	Target Neighborhood Hits	330	Shared Neighborhood Hits	261
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

MTPN_MOUSE
NC score	0.596903 (rank : 31)	θ value	0.000158464 (rank : 158)
Query Neighborhood Hits	395	Target Neighborhood Hits	269	Shared Neighborhood Hits	250
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

PSD10_MOUSE
NC score	0.596649 (rank : 32)	θ value	6.43352e-06 (rank : 100)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR46_HUMAN
NC score	0.596570 (rank : 33)	θ value	0.00035302 (rank : 173)
Query Neighborhood Hits	395	Target Neighborhood Hits	281	Shared Neighborhood Hits	253
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

GABP2_MOUSE
NC score	0.594445 (rank : 34)	θ value	4.92598e-06 (rank : 95)
Query Neighborhood Hits	395	Target Neighborhood Hits	429	Shared Neighborhood Hits	266
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

GABP2_HUMAN
NC score	0.593851 (rank : 35)	θ value	3.77169e-06 (rank : 87)
Query Neighborhood Hits	395	Target Neighborhood Hits	454	Shared Neighborhood Hits	267
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

MTPN_HUMAN
NC score	0.592410 (rank : 36)	θ value	0.000158464 (rank : 157)
Query Neighborhood Hits	395	Target Neighborhood Hits	269	Shared Neighborhood Hits	250
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

ANR46_MOUSE
NC score	0.590646 (rank : 37)	θ value	0.000158464 (rank : 154)
Query Neighborhood Hits	395	Target Neighborhood Hits	274	Shared Neighborhood Hits	248
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANKR6_HUMAN
NC score	0.590487 (rank : 38)	θ value	0.000158464 (rank : 149)
Query Neighborhood Hits	395	Target Neighborhood Hits	439	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR50_HUMAN
NC score	0.589447 (rank : 39)	θ value	2.79066e-09 (rank : 47)
Query Neighborhood Hits	395	Target Neighborhood Hits	361	Shared Neighborhood Hits	263
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ANKR2_HUMAN
NC score	0.588786 (rank : 40)	θ value	9.92553e-07 (rank : 72)
Query Neighborhood Hits	395	Target Neighborhood Hits	321	Shared Neighborhood Hits	262
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

TNKS1_HUMAN
NC score	0.587962 (rank : 41)	θ value	1.53129e-07 (rank : 59)
Query Neighborhood Hits	395	Target Neighborhood Hits	477	Shared Neighborhood Hits	267
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

TNKS2_HUMAN
NC score	0.587380 (rank : 42)	θ value	1.38499e-08 (rank : 51)
Query Neighborhood Hits	395	Target Neighborhood Hits	361	Shared Neighborhood Hits	266
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

ANR23_HUMAN
NC score	0.587115 (rank : 43)	θ value	1.87187e-05 (rank : 110)
Query Neighborhood Hits	395	Target Neighborhood Hits	291	Shared Neighborhood Hits	258
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ARFG1_MOUSE
NC score	0.586506 (rank : 44)	θ value	4.91457e-14 (rank : 40)
Query Neighborhood Hits	395	Target Neighborhood Hits	51	Shared Neighborhood Hits	38
SwissProt Accessions	Q9EPJ9, Q3TI52, Q8BMM6, Q8BMQ7	Gene names	Arfgap1, Arf1gap
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

ANR29_HUMAN
NC score	0.585690 (rank : 45)	θ value	1.69304e-06 (rank : 79)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANKR2_MOUSE
NC score	0.585581 (rank : 46)	θ value	5.81887e-07 (rank : 69)
Query Neighborhood Hits	395	Target Neighborhood Hits	312	Shared Neighborhood Hits	261
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR44_HUMAN
NC score	0.584113 (rank : 47)	θ value	2.13673e-09 (rank : 45)
Query Neighborhood Hits	395	Target Neighborhood Hits	318	Shared Neighborhood Hits	260
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR23_MOUSE
NC score	0.582806 (rank : 48)	θ value	0.000158464 (rank : 152)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	257
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ANR52_MOUSE
NC score	0.582402 (rank : 49)	θ value	1.06045e-08 (rank : 50)
Query Neighborhood Hits	395	Target Neighborhood Hits	318	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB8_HUMAN
NC score	0.582283 (rank : 50)	θ value	2.44474e-05 (rank : 116)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	259
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR52_HUMAN
NC score	0.582011 (rank : 51)	θ value	1.06045e-08 (rank : 49)
Query Neighborhood Hits	395	Target Neighborhood Hits	322	Shared Neighborhood Hits	260
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB8_MOUSE
NC score	0.581716 (rank : 52)	θ value	2.44474e-05 (rank : 117)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	257
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR28_MOUSE
NC score	0.581469 (rank : 53)	θ value	8.97725e-08 (rank : 56)
Query Neighborhood Hits	395	Target Neighborhood Hits	314	Shared Neighborhood Hits	261
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

MYPT1_MOUSE
NC score	0.581319 (rank : 54)	θ value	4.45536e-07 (rank : 67)
Query Neighborhood Hits	395	Target Neighborhood Hits	539	Shared Neighborhood Hits	271
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANR42_HUMAN
NC score	0.580646 (rank : 55)	θ value	0.000158464 (rank : 153)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	256
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR28_HUMAN
NC score	0.579904 (rank : 56)	θ value	2.88788e-06 (rank : 83)
Query Neighborhood Hits	395	Target Neighborhood Hits	314	Shared Neighborhood Hits	261
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANKR1_HUMAN
NC score	0.579731 (rank : 57)	θ value	9.29e-05 (rank : 143)
Query Neighborhood Hits	395	Target Neighborhood Hits	308	Shared Neighborhood Hits	258
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR5_MOUSE
NC score	0.579502 (rank : 58)	θ value	2.36244e-08 (rank : 53)
Query Neighborhood Hits	395	Target Neighborhood Hits	298	Shared Neighborhood Hits	256
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

CDN2D_HUMAN
NC score	0.579400 (rank : 59)	θ value	9.92553e-07 (rank : 73)
Query Neighborhood Hits	395	Target Neighborhood Hits	268	Shared Neighborhood Hits	246
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR42_MOUSE
NC score	0.579221 (rank : 60)	θ value	8.40245e-06 (rank : 101)
Query Neighborhood Hits	395	Target Neighborhood Hits	334	Shared Neighborhood Hits	260
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANK1_HUMAN
NC score	0.578082 (rank : 61)	θ value	2.79066e-09 (rank : 46)
Query Neighborhood Hits	395	Target Neighborhood Hits	416	Shared Neighborhood Hits	261
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANKR1_MOUSE
NC score	0.577709 (rank : 62)	θ value	0.00134147 (rank : 207)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB10_HUMAN
NC score	0.577651 (rank : 63)	θ value	0.000786445 (rank : 193)
Query Neighborhood Hits	395	Target Neighborhood Hits	291	Shared Neighborhood Hits	257
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ARFG3_HUMAN
NC score	0.577510 (rank : 64)	θ value	1.29331e-14 (rank : 39)
Query Neighborhood Hits	395	Target Neighborhood Hits	56	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ASB3_MOUSE
NC score	0.577411 (rank : 65)	θ value	1.43324e-05 (rank : 108)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	259
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKR5_HUMAN
NC score	0.577386 (rank : 66)	θ value	3.41135e-07 (rank : 64)
Query Neighborhood Hits	395	Target Neighborhood Hits	297	Shared Neighborhood Hits	257
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANK1_MOUSE
NC score	0.576396 (rank : 67)	θ value	8.11959e-09 (rank : 48)
Query Neighborhood Hits	395	Target Neighborhood Hits	430	Shared Neighborhood Hits	261
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

ARFG1_HUMAN
NC score	0.574700 (rank : 68)	θ value	8.38298e-14 (rank : 41)
Query Neighborhood Hits	395	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q8N6T3, Q96KC4, Q96T02, Q9NSU3, Q9NVF6, Q9UIL0	Gene names	ARFGAP1, ARF1GAP
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 1 (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase- activating protein) (GAP protein).

BCL3_HUMAN
NC score	0.574666 (rank : 69)	θ value	3.77169e-06 (rank : 86)
Query Neighborhood Hits	395	Target Neighborhood Hits	324	Shared Neighborhood Hits	259
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

ANRA2_MOUSE
NC score	0.574140 (rank : 70)	θ value	1.29631e-06 (rank : 76)
Query Neighborhood Hits	395	Target Neighborhood Hits	287	Shared Neighborhood Hits	252
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ARFG3_MOUSE
NC score	0.574080 (rank : 71)	θ value	9.90251e-15 (rank : 38)
Query Neighborhood Hits	395	Target Neighborhood Hits	80	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ASB10_MOUSE
NC score	0.573987 (rank : 72)	θ value	0.00035302 (rank : 174)
Query Neighborhood Hits	395	Target Neighborhood Hits	301	Shared Neighborhood Hits	258
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

FANK1_MOUSE
NC score	0.573949 (rank : 73)	θ value	9.29e-05 (rank : 146)
Query Neighborhood Hits	395	Target Neighborhood Hits	325	Shared Neighborhood Hits	259
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

FANK1_HUMAN
NC score	0.573430 (rank : 74)	θ value	0.000270298 (rank : 170)
Query Neighborhood Hits	395	Target Neighborhood Hits	326	Shared Neighborhood Hits	259
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ANRA2_HUMAN
NC score	0.573382 (rank : 75)	θ value	3.77169e-06 (rank : 85)
Query Neighborhood Hits	395	Target Neighborhood Hits	288	Shared Neighborhood Hits	251
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

BCL3_MOUSE
NC score	0.572270 (rank : 76)	θ value	2.44474e-05 (rank : 118)
Query Neighborhood Hits	395	Target Neighborhood Hits	388	Shared Neighborhood Hits	261
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ASB3_HUMAN
NC score	0.571621 (rank : 77)	θ value	7.1131e-05 (rank : 140)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	259
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANS4B_MOUSE
NC score	0.569877 (rank : 78)	θ value	1.29631e-06 (rank : 77)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	241
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

MYPT1_HUMAN
NC score	0.569778 (rank : 79)	θ value	4.45536e-07 (rank : 66)
Query Neighborhood Hits	395	Target Neighborhood Hits	723	Shared Neighborhood Hits	277
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ASB2_HUMAN
NC score	0.568829 (rank : 80)	θ value	7.59969e-07 (rank : 70)
Query Neighborhood Hits	395	Target Neighborhood Hits	309	Shared Neighborhood Hits	259
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ANR49_HUMAN
NC score	0.568743 (rank : 81)	θ value	0.00175202 (rank : 211)
Query Neighborhood Hits	395	Target Neighborhood Hits	282	Shared Neighborhood Hits	254
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

INVS_HUMAN
NC score	0.568333 (rank : 82)	θ value	2.44474e-05 (rank : 119)
Query Neighborhood Hits	395	Target Neighborhood Hits	455	Shared Neighborhood Hits	263
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANS4B_HUMAN
NC score	0.566645 (rank : 83)	θ value	4.92598e-06 (rank : 91)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	247
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANR49_MOUSE
NC score	0.566428 (rank : 84)	θ value	0.00102713 (rank : 199)
Query Neighborhood Hits	395	Target Neighborhood Hits	285	Shared Neighborhood Hits	253
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

PP16A_MOUSE
NC score	0.566199 (rank : 85)	θ value	1.99992e-07 (rank : 62)
Query Neighborhood Hits	395	Target Neighborhood Hits	318	Shared Neighborhood Hits	258
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

CDN2D_MOUSE
NC score	0.565994 (rank : 86)	θ value	4.92598e-06 (rank : 93)
Query Neighborhood Hits	395	Target Neighborhood Hits	267	Shared Neighborhood Hits	244
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB13_MOUSE
NC score	0.564847 (rank : 87)	θ value	0.00102713 (rank : 200)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	259
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB13_HUMAN
NC score	0.564661 (rank : 88)	θ value	0.00134147 (rank : 209)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	260
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

INVS_MOUSE
NC score	0.563322 (rank : 89)	θ value	1.43324e-05 (rank : 109)
Query Neighborhood Hits	395	Target Neighborhood Hits	609	Shared Neighborhood Hits	262
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ANK3_HUMAN
NC score	0.562982 (rank : 90)	θ value	3.77169e-06 (rank : 84)
Query Neighborhood Hits	395	Target Neighborhood Hits	853	Shared Neighborhood Hits	273
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR10_HUMAN
NC score	0.562909 (rank : 91)	θ value	0.0252991 (rank : 261)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	246
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANKS3_MOUSE
NC score	0.562846 (rank : 92)	θ value	0.00102713 (rank : 198)
Query Neighborhood Hits	395	Target Neighborhood Hits	355	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

MYPT2_HUMAN
NC score	0.562169 (rank : 93)	θ value	1.17247e-07 (rank : 58)
Query Neighborhood Hits	395	Target Neighborhood Hits	707	Shared Neighborhood Hits	274
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANR10_MOUSE
NC score	0.561120 (rank : 94)	θ value	7.1131e-05 (rank : 137)
Query Neighborhood Hits	395	Target Neighborhood Hits	273	Shared Neighborhood Hits	246
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB7_MOUSE
NC score	0.559555 (rank : 95)	θ value	0.0252991 (rank : 264)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	258
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB2_MOUSE
NC score	0.559355 (rank : 96)	θ value	4.92598e-06 (rank : 92)
Query Neighborhood Hits	395	Target Neighborhood Hits	321	Shared Neighborhood Hits	257
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB7_HUMAN
NC score	0.559283 (rank : 97)	θ value	0.0252991 (rank : 263)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	258
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANKS6_HUMAN
NC score	0.559041 (rank : 98)	θ value	7.1131e-05 (rank : 136)
Query Neighborhood Hits	395	Target Neighborhood Hits	411	Shared Neighborhood Hits	262
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR41_HUMAN
NC score	0.558237 (rank : 99)	θ value	7.1131e-05 (rank : 139)
Query Neighborhood Hits	395	Target Neighborhood Hits	332	Shared Neighborhood Hits	237
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANKS3_HUMAN
NC score	0.554677 (rank : 100)	θ value	0.00134147 (rank : 208)
Query Neighborhood Hits	395	Target Neighborhood Hits	355	Shared Neighborhood Hits	261
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANKS6_MOUSE
NC score	0.554396 (rank : 101)	θ value	0.00020696 (rank : 161)
Query Neighborhood Hits	395	Target Neighborhood Hits	435	Shared Neighborhood Hits	262
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

AN36B_HUMAN
NC score	0.554363 (rank : 102)	θ value	4.92598e-06 (rank : 90)
Query Neighborhood Hits	395	Target Neighborhood Hits	294	Shared Neighborhood Hits	253
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

BARD1_HUMAN
NC score	0.553038 (rank : 103)	θ value	8.40245e-06 (rank : 103)
Query Neighborhood Hits	395	Target Neighborhood Hits	427	Shared Neighborhood Hits	259
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

PA2G6_HUMAN
NC score	0.552697 (rank : 104)	θ value	0.0431538 (rank : 280)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	257
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PP16B_MOUSE
NC score	0.552669 (rank : 105)	θ value	0.000602161 (rank : 190)
Query Neighborhood Hits	395	Target Neighborhood Hits	302	Shared Neighborhood Hits	256
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ANR35_HUMAN
NC score	0.552622 (rank : 106)	θ value	4.45536e-07 (rank : 65)
Query Neighborhood Hits	395	Target Neighborhood Hits	784	Shared Neighborhood Hits	288
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

USH1G_MOUSE
NC score	0.552622 (rank : 107)	θ value	0.00020696 (rank : 166)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	248
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

PP16B_HUMAN
NC score	0.552153 (rank : 108)	θ value	0.00175202 (rank : 214)
Query Neighborhood Hits	395	Target Neighborhood Hits	307	Shared Neighborhood Hits	256
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

USH1G_HUMAN
NC score	0.551936 (rank : 109)	θ value	0.00020696 (rank : 165)
Query Neighborhood Hits	395	Target Neighborhood Hits	267	Shared Neighborhood Hits	248
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

ASB16_MOUSE
NC score	0.551831 (rank : 110)	θ value	0.0330416 (rank : 272)
Query Neighborhood Hits	395	Target Neighborhood Hits	306	Shared Neighborhood Hits	257
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANKR7_HUMAN
NC score	0.551358 (rank : 111)	θ value	0.000270298 (rank : 167)
Query Neighborhood Hits	395	Target Neighborhood Hits	286	Shared Neighborhood Hits	254
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

RFXK_HUMAN
NC score	0.550030 (rank : 112)	θ value	0.000461057 (rank : 188)
Query Neighborhood Hits	395	Target Neighborhood Hits	282	Shared Neighborhood Hits	250
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

BARD1_MOUSE
NC score	0.550000 (rank : 113)	θ value	1.87187e-05 (rank : 111)
Query Neighborhood Hits	395	Target Neighborhood Hits	411	Shared Neighborhood Hits	255
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

PA2G6_MOUSE
NC score	0.549939 (rank : 114)	θ value	0.0330416 (rank : 275)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	257
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

IKBB_MOUSE
NC score	0.549915 (rank : 115)	θ value	0.00134147 (rank : 210)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	255
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ASB16_HUMAN
NC score	0.548980 (rank : 116)	θ value	0.00298849 (rank : 222)
Query Neighborhood Hits	395	Target Neighborhood Hits	286	Shared Neighborhood Hits	253
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASZ1_MOUSE
NC score	0.547986 (rank : 117)	θ value	0.00869519 (rank : 247)
Query Neighborhood Hits	395	Target Neighborhood Hits	319	Shared Neighborhood Hits	259
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

TRPA1_MOUSE
NC score	0.547660 (rank : 118)	θ value	0.000602161 (rank : 191)
Query Neighborhood Hits	395	Target Neighborhood Hits	343	Shared Neighborhood Hits	260
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

CDN2C_MOUSE
NC score	0.546770 (rank : 119)	θ value	0.00665767 (rank : 238)
Query Neighborhood Hits	395	Target Neighborhood Hits	270	Shared Neighborhood Hits	248
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

CDN2C_HUMAN
NC score	0.546524 (rank : 120)	θ value	0.000786445 (rank : 195)
Query Neighborhood Hits	395	Target Neighborhood Hits	262	Shared Neighborhood Hits	246
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ACBD6_MOUSE
NC score	0.546468 (rank : 121)	θ value	0.0193708 (rank : 256)
Query Neighborhood Hits	395	Target Neighborhood Hits	305	Shared Neighborhood Hits	256
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR22_HUMAN
NC score	0.546171 (rank : 122)	θ value	0.21417 (rank : 295)
Query Neighborhood Hits	395	Target Neighborhood Hits	243	Shared Neighborhood Hits	228
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ACBD6_HUMAN
NC score	0.545828 (rank : 123)	θ value	0.0193708 (rank : 255)
Query Neighborhood Hits	395	Target Neighborhood Hits	304	Shared Neighborhood Hits	259
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANR16_HUMAN
NC score	0.545299 (rank : 124)	θ value	1.06291 (rank : 326)
Query Neighborhood Hits	395	Target Neighborhood Hits	286	Shared Neighborhood Hits	255
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

PP16A_HUMAN
NC score	0.543997 (rank : 125)	θ value	0.000786445 (rank : 197)
Query Neighborhood Hits	395	Target Neighborhood Hits	340	Shared Neighborhood Hits	254
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

EHMT1_HUMAN
NC score	0.543904 (rank : 126)	θ value	3.19293e-05 (rank : 124)
Query Neighborhood Hits	395	Target Neighborhood Hits	417	Shared Neighborhood Hits	263
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

EHMT2_HUMAN
NC score	0.542897 (rank : 127)	θ value	2.61198e-07 (rank : 63)
Query Neighborhood Hits	395	Target Neighborhood Hits	498	Shared Neighborhood Hits	264
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

IKBE_MOUSE
NC score	0.542518 (rank : 128)	θ value	0.00035302 (rank : 176)
Query Neighborhood Hits	395	Target Neighborhood Hits	308	Shared Neighborhood Hits	255
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

ASB15_HUMAN
NC score	0.542114 (rank : 129)	θ value	9.29e-05 (rank : 144)
Query Neighborhood Hits	395	Target Neighborhood Hits	305	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

TRPA1_HUMAN
NC score	0.541736 (rank : 130)	θ value	0.00298849 (rank : 225)
Query Neighborhood Hits	395	Target Neighborhood Hits	339	Shared Neighborhood Hits	260
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

CSKI2_HUMAN
NC score	0.541233 (rank : 131)	θ value	9.92553e-07 (rank : 74)
Query Neighborhood Hits	395	Target Neighborhood Hits	747	Shared Neighborhood Hits	270
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB14_MOUSE
NC score	0.541077 (rank : 132)	θ value	5.44631e-05 (rank : 134)
Query Neighborhood Hits	395	Target Neighborhood Hits	293	Shared Neighborhood Hits	258
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CSKI2_MOUSE
NC score	0.540702 (rank : 133)	θ value	1.29631e-06 (rank : 78)
Query Neighborhood Hits	395	Target Neighborhood Hits	812	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB11_MOUSE
NC score	0.539659 (rank : 134)	θ value	0.00035302 (rank : 175)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	244
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

RFXK_MOUSE
NC score	0.539095 (rank : 135)	θ value	0.0193708 (rank : 257)
Query Neighborhood Hits	395	Target Neighborhood Hits	273	Shared Neighborhood Hits	250
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

RN5A_HUMAN
NC score	0.537437 (rank : 136)	θ value	1.09739e-05 (rank : 107)
Query Neighborhood Hits	395	Target Neighborhood Hits	608	Shared Neighborhood Hits	258
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASZ1_HUMAN
NC score	0.537189 (rank : 137)	θ value	0.0330416 (rank : 273)
Query Neighborhood Hits	395	Target Neighborhood Hits	341	Shared Neighborhood Hits	258
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

IKBB_HUMAN
NC score	0.537185 (rank : 138)	θ value	0.00390308 (rank : 226)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	253
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

AN36A_HUMAN
NC score	0.536967 (rank : 139)	θ value	0.000158464 (rank : 148)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	251
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

IKBE_HUMAN
NC score	0.535253 (rank : 140)	θ value	0.000461057 (rank : 183)
Query Neighborhood Hits	395	Target Neighborhood Hits	288	Shared Neighborhood Hits	252
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

ASB11_HUMAN
NC score	0.534609 (rank : 141)	θ value	0.000461057 (rank : 181)
Query Neighborhood Hits	395	Target Neighborhood Hits	271	Shared Neighborhood Hits	245
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANR37_HUMAN
NC score	0.534533 (rank : 142)	θ value	0.0330416 (rank : 271)
Query Neighborhood Hits	395	Target Neighborhood Hits	247	Shared Neighborhood Hits	234
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR19_HUMAN
NC score	0.534231 (rank : 143)	θ value	0.000158464 (rank : 150)
Query Neighborhood Hits	395	Target Neighborhood Hits	276	Shared Neighborhood Hits	251
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

CSKI1_HUMAN
NC score	0.533673 (rank : 144)	θ value	1.87187e-05 (rank : 112)
Query Neighborhood Hits	395	Target Neighborhood Hits	997	Shared Neighborhood Hits	271
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

POTE8_HUMAN
NC score	0.533367 (rank : 145)	θ value	1.87187e-05 (rank : 114)
Query Neighborhood Hits	395	Target Neighborhood Hits	337	Shared Neighborhood Hits	260
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

ANKS1_HUMAN
NC score	0.533158 (rank : 146)	θ value	4.1701e-05 (rank : 126)
Query Neighborhood Hits	395	Target Neighborhood Hits	438	Shared Neighborhood Hits	263
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

MIB2_HUMAN
NC score	0.532443 (rank : 147)	θ value	0.00102713 (rank : 204)
Query Neighborhood Hits	395	Target Neighborhood Hits	438	Shared Neighborhood Hits	259
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

CSKI1_MOUSE
NC score	0.532086 (rank : 148)	θ value	0.000270298 (rank : 169)
Query Neighborhood Hits	395	Target Neighborhood Hits	1031	Shared Neighborhood Hits	272
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANK2_HUMAN
NC score	0.531507 (rank : 149)	θ value	1.29631e-06 (rank : 75)
Query Neighborhood Hits	395	Target Neighborhood Hits	1615	Shared Neighborhood Hits	285
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MIB1_HUMAN
NC score	0.531188 (rank : 150)	θ value	0.00102713 (rank : 202)
Query Neighborhood Hits	395	Target Neighborhood Hits	470	Shared Neighborhood Hits	262
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.530898 (rank : 151)	θ value	0.00102713 (rank : 203)
Query Neighborhood Hits	395	Target Neighborhood Hits	471	Shared Neighborhood Hits	261
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

ASB12_HUMAN
NC score	0.530235 (rank : 152)	θ value	0.365318 (rank : 308)
Query Neighborhood Hits	395	Target Neighborhood Hits	263	Shared Neighborhood Hits	245
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

EHMT2_MOUSE
NC score	0.529551 (rank : 153)	θ value	1.99992e-07 (rank : 60)
Query Neighborhood Hits	395	Target Neighborhood Hits	750	Shared Neighborhood Hits	264
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB1_HUMAN
NC score	0.529388 (rank : 154)	θ value	0.000602161 (rank : 189)
Query Neighborhood Hits	395	Target Neighborhood Hits	291	Shared Neighborhood Hits	249
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB15_MOUSE
NC score	0.529312 (rank : 155)	θ value	0.0148317 (rank : 252)
Query Neighborhood Hits	395	Target Neighborhood Hits	292	Shared Neighborhood Hits	254
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ANR37_MOUSE
NC score	0.529108 (rank : 156)	θ value	0.0736092 (rank : 283)
Query Neighborhood Hits	395	Target Neighborhood Hits	237	Shared Neighborhood Hits	223
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

IKBA_HUMAN
NC score	0.528978 (rank : 157)	θ value	0.0330416 (rank : 274)
Query Neighborhood Hits	395	Target Neighborhood Hits	280	Shared Neighborhood Hits	256
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASB9_HUMAN
NC score	0.528638 (rank : 158)	θ value	0.0113563 (rank : 250)
Query Neighborhood Hits	395	Target Neighborhood Hits	267	Shared Neighborhood Hits	239
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MIB2_MOUSE
NC score	0.527271 (rank : 159)	θ value	0.00175202 (rank : 213)
Query Neighborhood Hits	395	Target Neighborhood Hits	409	Shared Neighborhood Hits	256
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ASB12_MOUSE
NC score	0.526641 (rank : 160)	θ value	0.62314 (rank : 320)
Query Neighborhood Hits	395	Target Neighborhood Hits	261	Shared Neighborhood Hits	243
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB5_HUMAN
NC score	0.526280 (rank : 161)	θ value	0.0252991 (rank : 262)
Query Neighborhood Hits	395	Target Neighborhood Hits	283	Shared Neighborhood Hits	251
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB9_MOUSE
NC score	0.526034 (rank : 162)	θ value	0.00665767 (rank : 237)
Query Neighborhood Hits	395	Target Neighborhood Hits	257	Shared Neighborhood Hits	237
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANKS1_MOUSE
NC score	0.525614 (rank : 163)	θ value	0.00035302 (rank : 171)
Query Neighborhood Hits	395	Target Neighborhood Hits	453	Shared Neighborhood Hits	265
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ASB1_MOUSE
NC score	0.524340 (rank : 164)	θ value	5.44631e-05 (rank : 135)
Query Neighborhood Hits	395	Target Neighborhood Hits	292	Shared Neighborhood Hits	247
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ASB5_MOUSE
NC score	0.522367 (rank : 165)	θ value	0.0563607 (rank : 282)
Query Neighborhood Hits	395	Target Neighborhood Hits	266	Shared Neighborhood Hits	243
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

IKBA_MOUSE
NC score	0.519871 (rank : 166)	θ value	0.0252991 (rank : 266)
Query Neighborhood Hits	395	Target Neighborhood Hits	283	Shared Neighborhood Hits	257
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

CEND1_HUMAN
NC score	0.518903 (rank : 167)	θ value	1.5773e-20 (rank : 25)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	98
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

ASB4_MOUSE
NC score	0.514983 (rank : 168)	θ value	0.0736092 (rank : 284)
Query Neighborhood Hits	395	Target Neighborhood Hits	265	Shared Neighborhood Hits	246
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_HUMAN
NC score	0.514708 (rank : 169)	θ value	0.21417 (rank : 296)
Query Neighborhood Hits	395	Target Neighborhood Hits	264	Shared Neighborhood Hits	246
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

CEND1_MOUSE
NC score	0.511814 (rank : 170)	θ value	9.24701e-21 (rank : 22)
Query Neighborhood Hits	395	Target Neighborhood Hits	260	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

ANFY1_HUMAN
NC score	0.509494 (rank : 171)	θ value	0.000786445 (rank : 192)
Query Neighborhood Hits	395	Target Neighborhood Hits	480	Shared Neighborhood Hits	270
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANFY1_MOUSE
NC score	0.508417 (rank : 172)	θ value	0.00509761 (rank : 230)
Query Neighborhood Hits	395	Target Neighborhood Hits	480	Shared Neighborhood Hits	270
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR15_HUMAN
NC score	0.506872 (rank : 173)	θ value	5.44631e-05 (rank : 133)
Query Neighborhood Hits	395	Target Neighborhood Hits	478	Shared Neighborhood Hits	265
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANKY2_HUMAN
NC score	0.506175 (rank : 174)	θ value	5.44631e-05 (rank : 132)
Query Neighborhood Hits	395	Target Neighborhood Hits	306	Shared Neighborhood Hits	244
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ZDH17_HUMAN
NC score	0.502505 (rank : 175)	θ value	0.00665767 (rank : 244)
Query Neighborhood Hits	395	Target Neighborhood Hits	334	Shared Neighborhood Hits	259
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

CEND2_HUMAN
NC score	0.502373 (rank : 176)	θ value	3.75424e-22 (rank : 15)
Query Neighborhood Hits	395	Target Neighborhood Hits	166	Shared Neighborhood Hits	79
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

CTTB2_HUMAN
NC score	0.501246 (rank : 177)	θ value	0.000461057 (rank : 182)
Query Neighborhood Hits	395	Target Neighborhood Hits	1061	Shared Neighborhood Hits	291
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

RN5A_MOUSE
NC score	0.500738 (rank : 178)	θ value	2.44474e-05 (rank : 120)
Query Neighborhood Hits	395	Target Neighborhood Hits	899	Shared Neighborhood Hits	258
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ZDH17_MOUSE
NC score	0.498722 (rank : 179)	θ value	0.00665767 (rank : 245)
Query Neighborhood Hits	395	Target Neighborhood Hits	328	Shared Neighborhood Hits	256
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR21_HUMAN
NC score	0.494547 (rank : 180)	θ value	0.000158464 (rank : 151)
Query Neighborhood Hits	395	Target Neighborhood Hits	864	Shared Neighborhood Hits	279
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.492680 (rank : 181)	θ value	0.0330416 (rank : 277)
Query Neighborhood Hits	395	Target Neighborhood Hits	893	Shared Neighborhood Hits	277
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

ANR11_HUMAN
NC score	0.489289 (rank : 182)	θ value	0.000461057 (rank : 180)
Query Neighborhood Hits	395	Target Neighborhood Hits	1289	Shared Neighborhood Hits	275
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

ANR47_MOUSE
NC score	0.489285 (rank : 183)	θ value	1.69304e-06 (rank : 80)
Query Neighborhood Hits	395	Target Neighborhood Hits	350	Shared Neighborhood Hits	247
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

SHAN1_HUMAN
NC score	0.487386 (rank : 184)	θ value	8.40245e-06 (rank : 104)
Query Neighborhood Hits	395	Target Neighborhood Hits	1041	Shared Neighborhood Hits	265
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANR12_HUMAN
NC score	0.486428 (rank : 185)	θ value	4.1701e-05 (rank : 127)
Query Neighborhood Hits	395	Target Neighborhood Hits	1081	Shared Neighborhood Hits	278
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ZDH13_MOUSE
NC score	0.484975 (rank : 186)	θ value	0.0252991 (rank : 269)
Query Neighborhood Hits	395	Target Neighborhood Hits	329	Shared Neighborhood Hits	258
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

CEND3_HUMAN
NC score	0.484943 (rank : 187)	θ value	1.058e-16 (rank : 30)
Query Neighborhood Hits	395	Target Neighborhood Hits	275	Shared Neighborhood Hits	70
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

ZDH13_HUMAN
NC score	0.484019 (rank : 188)	θ value	0.0193708 (rank : 258)
Query Neighborhood Hits	395	Target Neighborhood Hits	322	Shared Neighborhood Hits	256
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANKY2_MOUSE
NC score	0.482999 (rank : 189)	θ value	0.00228821 (rank : 216)
Query Neighborhood Hits	395	Target Neighborhood Hits	316	Shared Neighborhood Hits	243
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

POT14_HUMAN
NC score	0.482653 (rank : 190)	θ value	0.21417 (rank : 298)
Query Neighborhood Hits	395	Target Neighborhood Hits	403	Shared Neighborhood Hits	254
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

CEND3_MOUSE
NC score	0.479010 (rank : 191)	θ value	7.58209e-15 (rank : 37)
Query Neighborhood Hits	395	Target Neighborhood Hits	228	Shared Neighborhood Hits	70
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

NFKB2_HUMAN
NC score	0.478812 (rank : 192)	θ value	0.00020696 (rank : 163)
Query Neighborhood Hits	395	Target Neighborhood Hits	325	Shared Neighborhood Hits	259
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR32_HUMAN
NC score	0.476926 (rank : 193)	θ value	1.06291 (rank : 327)
Query Neighborhood Hits	395	Target Neighborhood Hits	270	Shared Neighborhood Hits	242
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

A20A2_HUMAN
NC score	0.476371 (rank : 194)	θ value	6.43352e-06 (rank : 99)
Query Neighborhood Hits	395	Target Neighborhood Hits	716	Shared Neighborhood Hits	275
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

A20A3_HUMAN
NC score	0.476083 (rank : 195)	θ value	2.88788e-06 (rank : 81)
Query Neighborhood Hits	395	Target Neighborhood Hits	692	Shared Neighborhood Hits	274
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

ANR33_HUMAN
NC score	0.474911 (rank : 196)	θ value	0.125558 (rank : 290)
Query Neighborhood Hits	395	Target Neighborhood Hits	215	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR33_MOUSE
NC score	0.474342 (rank : 197)	θ value	0.365318 (rank : 307)
Query Neighborhood Hits	395	Target Neighborhood Hits	225	Shared Neighborhood Hits	215
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

A20A1_HUMAN
NC score	0.473980 (rank : 198)	θ value	6.43352e-06 (rank : 98)
Query Neighborhood Hits	395	Target Neighborhood Hits	698	Shared Neighborhood Hits	273
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

BCOR_MOUSE
NC score	0.473151 (rank : 199)	θ value	0.00509761 (rank : 234)
Query Neighborhood Hits	395	Target Neighborhood Hits	521	Shared Neighborhood Hits	249
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

A20A4_HUMAN
NC score	0.472699 (rank : 200)	θ value	2.88788e-06 (rank : 82)
Query Neighborhood Hits	395	Target Neighborhood Hits	710	Shared Neighborhood Hits	274
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ASB6_HUMAN
NC score	0.472506 (rank : 201)	θ value	0.279714 (rank : 299)
Query Neighborhood Hits	395	Target Neighborhood Hits	256	Shared Neighborhood Hits	229
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR32_MOUSE
NC score	0.472187 (rank : 202)	θ value	2.36792 (rank : 344)
Query Neighborhood Hits	395	Target Neighborhood Hits	285	Shared Neighborhood Hits	242
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ANR47_HUMAN
NC score	0.471581 (rank : 203)	θ value	8.40245e-06 (rank : 102)
Query Neighborhood Hits	395	Target Neighborhood Hits	369	Shared Neighborhood Hits	244
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

NFKB1_HUMAN
NC score	0.470268 (rank : 204)	θ value	0.00665767 (rank : 240)
Query Neighborhood Hits	395	Target Neighborhood Hits	306	Shared Neighborhood Hits	256
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

NFKB1_MOUSE
NC score	0.469267 (rank : 205)	θ value	0.000461057 (rank : 185)
Query Neighborhood Hits	395	Target Neighborhood Hits	300	Shared Neighborhood Hits	251
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB2_MOUSE
NC score	0.467582 (rank : 206)	θ value	0.000158464 (rank : 159)
Query Neighborhood Hits	395	Target Neighborhood Hits	326	Shared Neighborhood Hits	255
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ASB6_MOUSE
NC score	0.467227 (rank : 207)	θ value	0.62314 (rank : 321)
Query Neighborhood Hits	395	Target Neighborhood Hits	264	Shared Neighborhood Hits	234
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

BCOR_HUMAN
NC score	0.465039 (rank : 208)	θ value	0.00509761 (rank : 233)
Query Neighborhood Hits	395	Target Neighborhood Hits	609	Shared Neighborhood Hits	252
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

SNCAP_HUMAN
NC score	0.460668 (rank : 209)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	395	Target Neighborhood Hits	313	Shared Neighborhood Hits	224
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

RAI14_HUMAN
NC score	0.460503 (rank : 210)	θ value	7.34386e-10 (rank : 43)
Query Neighborhood Hits	395	Target Neighborhood Hits	1367	Shared Neighborhood Hits	301
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

POT22_HUMAN
NC score	0.457047 (rank : 211)	θ value	0.163984 (rank : 293)
Query Neighborhood Hits	395	Target Neighborhood Hits	266	Shared Neighborhood Hits	245
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

HECD1_HUMAN
NC score	0.454440 (rank : 212)	θ value	1.99992e-07 (rank : 61)
Query Neighborhood Hits	395	Target Neighborhood Hits	371	Shared Neighborhood Hits	253
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

CD2A1_MOUSE
NC score	0.448111 (rank : 213)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	395	Target Neighborhood Hits	206	Shared Neighborhood Hits	192
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

ANR25_HUMAN
NC score	0.446988 (rank : 214)	θ value	0.365318 (rank : 306)
Query Neighborhood Hits	395	Target Neighborhood Hits	350	Shared Neighborhood Hits	242
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

CLPB_MOUSE
NC score	0.440854 (rank : 215)	θ value	0.279714 (rank : 300)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	233
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

MPP8_HUMAN
NC score	0.440381 (rank : 216)	θ value	0.000461057 (rank : 184)
Query Neighborhood Hits	395	Target Neighborhood Hits	948	Shared Neighborhood Hits	257
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

OSBL1_HUMAN
NC score	0.438143 (rank : 217)	θ value	0.00665767 (rank : 241)
Query Neighborhood Hits	395	Target Neighborhood Hits	368	Shared Neighborhood Hits	264
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

RAI14_MOUSE
NC score	0.436035 (rank : 218)	θ value	7.34386e-10 (rank : 44)
Query Neighborhood Hits	395	Target Neighborhood Hits	1505	Shared Neighborhood Hits	296
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ANR25_MOUSE
NC score	0.432995 (rank : 219)	θ value	0.62314 (rank : 319)
Query Neighborhood Hits	395	Target Neighborhood Hits	398	Shared Neighborhood Hits	240
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

OSTF1_MOUSE
NC score	0.432549 (rank : 220)	θ value	0.00228821 (rank : 221)
Query Neighborhood Hits	395	Target Neighborhood Hits	467	Shared Neighborhood Hits	235
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR18_HUMAN
NC score	0.431520 (rank : 221)	θ value	0.000270298 (rank : 168)
Query Neighborhood Hits	395	Target Neighborhood Hits	1106	Shared Neighborhood Hits	291
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

KRIT1_MOUSE
NC score	0.430248 (rank : 222)	θ value	0.00665767 (rank : 239)
Query Neighborhood Hits	395	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

OSBL1_MOUSE
NC score	0.430051 (rank : 223)	θ value	0.00035302 (rank : 178)
Query Neighborhood Hits	395	Target Neighborhood Hits	336	Shared Neighborhood Hits	263
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

KRIT1_HUMAN
NC score	0.418383 (rank : 224)	θ value	0.125558 (rank : 292)
Query Neighborhood Hits	395	Target Neighborhood Hits	258	Shared Neighborhood Hits	212
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

OSTF1_HUMAN
NC score	0.413225 (rank : 225)	θ value	0.0148317 (rank : 253)
Query Neighborhood Hits	395	Target Neighborhood Hits	466	Shared Neighborhood Hits	235
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR38_HUMAN
NC score	0.411524 (rank : 226)	θ value	8.99809 (rank : 385)
Query Neighborhood Hits	395	Target Neighborhood Hits	443	Shared Neighborhood Hits	238
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR45_MOUSE
NC score	0.405455 (rank : 227)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	180
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

NUPL_HUMAN
NC score	0.405287 (rank : 228)	θ value	3.77169e-06 (rank : 88)
Query Neighborhood Hits	395	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

IASPP_HUMAN
NC score	0.404517 (rank : 229)	θ value	0.00509761 (rank : 235)
Query Neighborhood Hits	395	Target Neighborhood Hits	688	Shared Neighborhood Hits	247
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

NUPL_MOUSE
NC score	0.400867 (rank : 230)	θ value	3.77169e-06 (rank : 89)
Query Neighborhood Hits	395	Target Neighborhood Hits	113	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

CDN2B_MOUSE
NC score	0.400792 (rank : 231)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	395	Target Neighborhood Hits	201	Shared Neighborhood Hits	189
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CD2A1_HUMAN
NC score	0.400106 (rank : 232)	θ value	4.03905 (rank : 357)
Query Neighborhood Hits	395	Target Neighborhood Hits	196	Shared Neighborhood Hits	181
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ASPP2_HUMAN
NC score	0.396181 (rank : 233)	θ value	0.000786445 (rank : 194)
Query Neighborhood Hits	395	Target Neighborhood Hits	1156	Shared Neighborhood Hits	281
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANR43_HUMAN
NC score	0.394666 (rank : 234)	θ value	1.81305 (rank : 335)
Query Neighborhood Hits	395	Target Neighborhood Hits	209	Shared Neighborhood Hits	198
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CDN2B_HUMAN
NC score	0.393468 (rank : 235)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	395	Target Neighborhood Hits	196	Shared Neighborhood Hits	187
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

ANR38_MOUSE
NC score	0.393178 (rank : 236)	θ value	5.27518 (rank : 365)
Query Neighborhood Hits	395	Target Neighborhood Hits	512	Shared Neighborhood Hits	236
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR43_MOUSE
NC score	0.391674 (rank : 237)	θ value	3.0926 (rank : 348)
Query Neighborhood Hits	395	Target Neighborhood Hits	214	Shared Neighborhood Hits	201
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

AN30A_HUMAN
NC score	0.386181 (rank : 238)	θ value	0.0252991 (rank : 260)
Query Neighborhood Hits	395	Target Neighborhood Hits	1119	Shared Neighborhood Hits	282
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ASPP1_HUMAN
NC score	0.382437 (rank : 239)	θ value	0.00509761 (rank : 231)
Query Neighborhood Hits	395	Target Neighborhood Hits	956	Shared Neighborhood Hits	270
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CLPB_HUMAN
NC score	0.381189 (rank : 240)	θ value	2.36792 (rank : 346)
Query Neighborhood Hits	395	Target Neighborhood Hits	265	Shared Neighborhood Hits	219
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

DP13A_MOUSE
NC score	0.380877 (rank : 241)	θ value	2.43343e-21 (rank : 17)
Query Neighborhood Hits	395	Target Neighborhood Hits	96	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_HUMAN
NC score	0.379676 (rank : 242)	θ value	9.24701e-21 (rank : 23)
Query Neighborhood Hits	395	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

AN13B_MOUSE
NC score	0.377865 (rank : 243)	θ value	0.00665767 (rank : 236)
Query Neighborhood Hits	395	Target Neighborhood Hits	276	Shared Neighborhood Hits	240
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANR45_HUMAN
NC score	0.377710 (rank : 244)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	395	Target Neighborhood Hits	201	Shared Neighborhood Hits	175
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

AN13B_HUMAN
NC score	0.376971 (rank : 245)	θ value	0.00869519 (rank : 246)
Query Neighborhood Hits	395	Target Neighborhood Hits	265	Shared Neighborhood Hits	240
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

DP13B_MOUSE
NC score	0.376822 (rank : 246)	θ value	8.65492e-19 (rank : 29)
Query Neighborhood Hits	395	Target Neighborhood Hits	58	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K3G9, Q99LT7	Gene names	Dip13b, Appl2, Dip3b
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

IASPP_MOUSE
NC score	0.376759 (rank : 247)	θ value	0.00298849 (rank : 223)
Query Neighborhood Hits	395	Target Neighborhood Hits	1024	Shared Neighborhood Hits	254
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

AN13C_HUMAN
NC score	0.376731 (rank : 248)	θ value	0.0330416 (rank : 270)
Query Neighborhood Hits	395	Target Neighborhood Hits	241	Shared Neighborhood Hits	228
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASPP1_MOUSE
NC score	0.375463 (rank : 249)	θ value	0.00509761 (rank : 232)
Query Neighborhood Hits	395	Target Neighborhood Hits	1244	Shared Neighborhood Hits	275
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

UACA_HUMAN
NC score	0.370992 (rank : 250)	θ value	5.62301e-10 (rank : 42)
Query Neighborhood Hits	395	Target Neighborhood Hits	1622	Shared Neighborhood Hits	296
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

AN13C_MOUSE
NC score	0.370309 (rank : 251)	θ value	0.0252991 (rank : 259)
Query Neighborhood Hits	395	Target Neighborhood Hits	242	Shared Neighborhood Hits	224
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

DP13B_HUMAN
NC score	0.369168 (rank : 252)	θ value	1.2077e-20 (rank : 24)
Query Neighborhood Hits	395	Target Neighborhood Hits	58	Shared Neighborhood Hits	29
SwissProt Accessions	Q8NEU8, Q8N4R7, Q9NVL2	Gene names	DIP13B, APPL2
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 beta (Dip13 beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2).

ABTB2_HUMAN
NC score	0.368437 (rank : 253)	θ value	0.0431538 (rank : 278)
Query Neighborhood Hits	395	Target Neighborhood Hits	391	Shared Neighborhood Hits	226
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANKK1_HUMAN
NC score	0.364156 (rank : 254)	θ value	8.97725e-08 (rank : 55)
Query Neighborhood Hits	395	Target Neighborhood Hits	1075	Shared Neighborhood Hits	262
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

HRBL_HUMAN
NC score	0.357297 (rank : 255)	θ value	3.19293e-05 (rank : 125)
Query Neighborhood Hits	395	Target Neighborhood Hits	179	Shared Neighborhood Hits	38
SwissProt Accessions	O95081, O75429, Q96AB9, Q96GL4	Gene names	HRBL, RABR
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ABTB2_MOUSE
NC score	0.356891 (rank : 256)	θ value	0.365318 (rank : 305)
Query Neighborhood Hits	395	Target Neighborhood Hits	414	Shared Neighborhood Hits	225
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

ANKK1_MOUSE
NC score	0.356639 (rank : 257)	θ value	1.17247e-07 (rank : 57)
Query Neighborhood Hits	395	Target Neighborhood Hits	1072	Shared Neighborhood Hits	262
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

NUD12_MOUSE
NC score	0.356516 (rank : 258)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	395	Target Neighborhood Hits	243	Shared Neighborhood Hits	210
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

RIPK4_HUMAN
NC score	0.353232 (rank : 259)	θ value	0.00020696 (rank : 164)
Query Neighborhood Hits	395	Target Neighborhood Hits	1094	Shared Neighborhood Hits	262
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

UACA_MOUSE
NC score	0.351951 (rank : 260)	θ value	1.38499e-08 (rank : 52)
Query Neighborhood Hits	395	Target Neighborhood Hits	1620	Shared Neighborhood Hits	292
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

ILK2_HUMAN
NC score	0.351151 (rank : 261)	θ value	0.00390308 (rank : 228)
Query Neighborhood Hits	395	Target Neighborhood Hits	848	Shared Neighborhood Hits	257
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

HRBL_MOUSE
NC score	0.349657 (rank : 262)	θ value	1.87187e-05 (rank : 113)
Query Neighborhood Hits	395	Target Neighborhood Hits	269	Shared Neighborhood Hits	44
SwissProt Accessions	Q80WC7, Q8BKS5, Q99J67	Gene names	Hrbl, Rabr
Domain Architecture
Description	HIV-1 Rev-binding protein-like protein (Rev/Rex activation domain- binding protein related) (RAB-R).

ANR40_HUMAN
NC score	0.349187 (rank : 263)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	395	Target Neighborhood Hits	224	Shared Neighborhood Hits	192
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ANR40_MOUSE
NC score	0.345661 (rank : 264)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	395	Target Neighborhood Hits	228	Shared Neighborhood Hits	195
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

ILK1_HUMAN
NC score	0.338905 (rank : 265)	θ value	0.00390308 (rank : 227)
Query Neighborhood Hits	395	Target Neighborhood Hits	857	Shared Neighborhood Hits	257
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

NUD12_HUMAN
NC score	0.336777 (rank : 266)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	395	Target Neighborhood Hits	222	Shared Neighborhood Hits	188
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ILK_MOUSE
NC score	0.336743 (rank : 267)	θ value	0.00390308 (rank : 229)
Query Neighborhood Hits	395	Target Neighborhood Hits	858	Shared Neighborhood Hits	258
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ANR26_MOUSE
NC score	0.326689 (rank : 268)	θ value	0.00035302 (rank : 172)
Query Neighborhood Hits	395	Target Neighborhood Hits	1554	Shared Neighborhood Hits	297
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANKY1_HUMAN
NC score	0.325397 (rank : 269)	θ value	8.99809 (rank : 382)
Query Neighborhood Hits	395	Target Neighborhood Hits	248	Shared Neighborhood Hits	195
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

TRPV6_MOUSE
NC score	0.323343 (rank : 270)	θ value	1.06291 (rank : 331)
Query Neighborhood Hits	395	Target Neighborhood Hits	284	Shared Neighborhood Hits	235
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ASB14_HUMAN
NC score	0.319284 (rank : 271)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	395	Target Neighborhood Hits	187	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

CT012_MOUSE
NC score	0.314894 (rank : 272)	θ value	0.00175202 (rank : 212)
Query Neighborhood Hits	395	Target Neighborhood Hits	229	Shared Neighborhood Hits	169
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

GLSL_HUMAN
NC score	0.313598 (rank : 273)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	395	Target Neighborhood Hits	211	Shared Neighborhood Hits	188
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

NOTC4_MOUSE
NC score	0.309103 (rank : 274)	θ value	0.000121331 (rank : 147)
Query Neighborhood Hits	395	Target Neighborhood Hits	872	Shared Neighborhood Hits	258
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANR26_HUMAN
NC score	0.305807 (rank : 275)	θ value	0.0563607 (rank : 281)
Query Neighborhood Hits	395	Target Neighborhood Hits	1614	Shared Neighborhood Hits	296
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

AN13A_HUMAN
NC score	0.304879 (rank : 276)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	395	Target Neighborhood Hits	243	Shared Neighborhood Hits	204
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

NOTC4_HUMAN
NC score	0.303315 (rank : 277)	θ value	0.00102713 (rank : 205)
Query Neighborhood Hits	395	Target Neighborhood Hits	905	Shared Neighborhood Hits	259
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GLSL_MOUSE
NC score	0.302053 (rank : 278)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	395	Target Neighborhood Hits	212	Shared Neighborhood Hits	187
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TRPV5_MOUSE
NC score	0.294359 (rank : 279)	θ value	3.0926 (rank : 356)
Query Neighborhood Hits	395	Target Neighborhood Hits	278	Shared Neighborhood Hits	231
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TNI3K_HUMAN
NC score	0.293953 (rank : 280)	θ value	7.59969e-07 (rank : 71)
Query Neighborhood Hits	395	Target Neighborhood Hits	1084	Shared Neighborhood Hits	262
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

AN13A_MOUSE
NC score	0.288245 (rank : 281)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	395	Target Neighborhood Hits	226	Shared Neighborhood Hits	205
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

TNI3K_MOUSE
NC score	0.287840 (rank : 282)	θ value	4.1701e-05 (rank : 131)
Query Neighborhood Hits	395	Target Neighborhood Hits	1079	Shared Neighborhood Hits	262
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

OPHN1_MOUSE
NC score	0.286031 (rank : 283)	θ value	2.27762e-19 (rank : 27)
Query Neighborhood Hits	395	Target Neighborhood Hits	174	Shared Neighborhood Hits	28
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GLSK_HUMAN
NC score	0.282094 (rank : 284)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	176
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

NOTC3_MOUSE
NC score	0.276948 (rank : 285)	θ value	0.00228821 (rank : 220)
Query Neighborhood Hits	395	Target Neighborhood Hits	975	Shared Neighborhood Hits	263
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.275498 (rank : 286)	θ value	0.00228821 (rank : 219)
Query Neighborhood Hits	395	Target Neighborhood Hits	1062	Shared Neighborhood Hits	263
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

OPHN1_HUMAN
NC score	0.273263 (rank : 287)	θ value	3.88503e-19 (rank : 28)
Query Neighborhood Hits	395	Target Neighborhood Hits	161	Shared Neighborhood Hits	23
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

NOTC2_HUMAN
NC score	0.270620 (rank : 288)	θ value	0.00035302 (rank : 177)
Query Neighborhood Hits	395	Target Neighborhood Hits	1113	Shared Neighborhood Hits	262
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TEX14_MOUSE
NC score	0.269223 (rank : 289)	θ value	0.00869519 (rank : 249)
Query Neighborhood Hits	395	Target Neighborhood Hits	1333	Shared Neighborhood Hits	265
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

NOTC2_MOUSE
NC score	0.268297 (rank : 290)	θ value	0.000461057 (rank : 186)
Query Neighborhood Hits	395	Target Neighborhood Hits	1069	Shared Neighborhood Hits	262
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.266621 (rank : 291)	θ value	0.00298849 (rank : 224)
Query Neighborhood Hits	395	Target Neighborhood Hits	906	Shared Neighborhood Hits	262
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DGKI_HUMAN
NC score	0.265995 (rank : 292)	θ value	0.0431538 (rank : 279)
Query Neighborhood Hits	395	Target Neighborhood Hits	609	Shared Neighborhood Hits	210
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

TRPV5_HUMAN
NC score	0.265975 (rank : 293)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	395	Target Neighborhood Hits	261	Shared Neighborhood Hits	207
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

RHG26_HUMAN
NC score	0.264139 (rank : 294)	θ value	2.43343e-21 (rank : 18)
Query Neighborhood Hits	395	Target Neighborhood Hits	281	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

DGKZ_HUMAN
NC score	0.263295 (rank : 295)	θ value	0.47712 (rank : 314)
Query Neighborhood Hits	395	Target Neighborhood Hits	551	Shared Neighborhood Hits	209
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

TEX14_HUMAN
NC score	0.262611 (rank : 296)	θ value	0.365318 (rank : 312)
Query Neighborhood Hits	395	Target Neighborhood Hits	1103	Shared Neighborhood Hits	242
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TRPV6_HUMAN
NC score	0.260302 (rank : 297)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	395	Target Neighborhood Hits	262	Shared Neighborhood Hits	209
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

CT012_HUMAN
NC score	0.259715 (rank : 298)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	395	Target Neighborhood Hits	205	Shared Neighborhood Hits	162
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DAPK1_MOUSE
NC score	0.254678 (rank : 299)	θ value	0.000158464 (rank : 156)
Query Neighborhood Hits	395	Target Neighborhood Hits	1138	Shared Neighborhood Hits	261
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

PKHA1_HUMAN
NC score	0.252790 (rank : 300)	θ value	0.00035302 (rank : 179)
Query Neighborhood Hits	395	Target Neighborhood Hits	127	Shared Neighborhood Hits	68
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
NC score	0.251597 (rank : 301)	θ value	0.000158464 (rank : 160)
Query Neighborhood Hits	395	Target Neighborhood Hits	120	Shared Neighborhood Hits	66
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

DAPK1_HUMAN
NC score	0.246606 (rank : 302)	θ value	7.1131e-05 (rank : 142)
Query Neighborhood Hits	395	Target Neighborhood Hits	1130	Shared Neighborhood Hits	260
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DGKZ_MOUSE
NC score	0.240588 (rank : 303)	θ value	1.38821 (rank : 333)
Query Neighborhood Hits	395	Target Neighborhood Hits	542	Shared Neighborhood Hits	193
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

PKHA6_MOUSE
NC score	0.227012 (rank : 304)	θ value	4.45536e-07 (rank : 68)
Query Neighborhood Hits	395	Target Neighborhood Hits	591	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA2_MOUSE
NC score	0.226619 (rank : 305)	θ value	1.09739e-05 (rank : 106)
Query Neighborhood Hits	395	Target Neighborhood Hits	116	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ERS5, Q8BY29	Gene names	Plekha2, Tapp2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2) (PH domain-containing adaptor PHAD47).

PKHA6_HUMAN
NC score	0.225298 (rank : 306)	θ value	4.0297e-08 (rank : 54)
Query Neighborhood Hits	395	Target Neighborhood Hits	556	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

PKHA2_HUMAN
NC score	0.222022 (rank : 307)	θ value	1.09739e-05 (rank : 105)
Query Neighborhood Hits	395	Target Neighborhood Hits	119	Shared Neighborhood Hits	65
SwissProt Accessions	Q9HB19	Gene names	PLEKHA2, TAPP2
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 2 (Tandem PH domain-containing protein 2) (TAPP-2).

NOTC1_MOUSE
NC score	0.221725 (rank : 308)	θ value	0.0252991 (rank : 267)
Query Neighborhood Hits	395	Target Neighborhood Hits	916	Shared Neighborhood Hits	245
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKZ1_MOUSE
NC score	0.212566 (rank : 309)	θ value	8.99809 (rank : 384)
Query Neighborhood Hits	395	Target Neighborhood Hits	208	Shared Neighborhood Hits	145
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

IKBL_HUMAN
NC score	0.202024 (rank : 310)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	395	Target Neighborhood Hits	168	Shared Neighborhood Hits	138
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
NC score	0.198649 (rank : 311)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	395	Target Neighborhood Hits	196	Shared Neighborhood Hits	143
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ANKZ1_HUMAN
NC score	0.196874 (rank : 312)	θ value	8.99809 (rank : 383)
Query Neighborhood Hits	395	Target Neighborhood Hits	236	Shared Neighborhood Hits	150
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANKR9_MOUSE
NC score	0.195316 (rank : 313)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	395	Target Neighborhood Hits	120	Shared Neighborhood Hits	114
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ABTB1_MOUSE
NC score	0.177481 (rank : 314)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	395	Target Neighborhood Hits	349	Shared Neighborhood Hits	166
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

BAT4_MOUSE
NC score	0.174404 (rank : 315)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	395	Target Neighborhood Hits	171	Shared Neighborhood Hits	112
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

PKHA4_MOUSE
NC score	0.172689 (rank : 316)	θ value	0.0330416 (rank : 276)
Query Neighborhood Hits	395	Target Neighborhood Hits	202	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VC98, Q8R3N3	Gene names	Plekha4, Pepp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CYH1_HUMAN
NC score	0.171652 (rank : 317)	θ value	3.19293e-05 (rank : 121)
Query Neighborhood Hits	395	Target Neighborhood Hits	184	Shared Neighborhood Hits	77
SwissProt Accessions	Q15438, Q9P123, Q9P124	Gene names	PSCD1, D17S811E
Domain Architecture
Description	Cytohesin-1 (SEC7 homolog B2-1).

BAT4_HUMAN
NC score	0.170893 (rank : 318)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	395	Target Neighborhood Hits	157	Shared Neighborhood Hits	102
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CYH1_MOUSE
NC score	0.170750 (rank : 319)	θ value	4.1701e-05 (rank : 128)
Query Neighborhood Hits	395	Target Neighborhood Hits	176	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QX11, O88817	Gene names	Pscd1
Domain Architecture
Description	Cytohesin-1 (CLM1).

PKHA4_HUMAN
NC score	0.170370 (rank : 320)	θ value	0.0252991 (rank : 268)
Query Neighborhood Hits	395	Target Neighborhood Hits	283	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H4M7, Q8N4M8, Q8N658	Gene names	PLEKHA4, PEPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 4 (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1).

CYH2_HUMAN
NC score	0.169186 (rank : 321)	θ value	3.19293e-05 (rank : 122)
Query Neighborhood Hits	395	Target Neighborhood Hits	175	Shared Neighborhood Hits	75
SwissProt Accessions	Q99418, Q92958	Gene names	PSCD2, ARNO
Domain Architecture
Description	Cytohesin-2 (ARF nucleotide-binding site opener) (ARNO protein) (ARF exchange factor).

CYH2_MOUSE
NC score	0.169020 (rank : 322)	θ value	3.19293e-05 (rank : 123)
Query Neighborhood Hits	395	Target Neighborhood Hits	171	Shared Neighborhood Hits	74
SwissProt Accessions	P63034, O89099, P97695, Q3UP39	Gene names	Pscd2, Sec7b
Domain Architecture	No domain graphic available
Description	Cytohesin-2 (CLM2) (SEC7 homolog B) (msec7-2).

CYH3_HUMAN
NC score	0.168926 (rank : 323)	θ value	4.92598e-06 (rank : 94)
Query Neighborhood Hits	395	Target Neighborhood Hits	137	Shared Neighborhood Hits	63
SwissProt Accessions	O43739	Gene names	PSCD3, ARNO3, GRP1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1).

PKHA5_HUMAN
NC score	0.166365 (rank : 324)	θ value	0.000461057 (rank : 187)
Query Neighborhood Hits	395	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

CLR59_HUMAN
NC score	0.163248 (rank : 325)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	395	Target Neighborhood Hits	163	Shared Neighborhood Hits	133
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

DAPP1_MOUSE
NC score	0.162810 (rank : 326)	θ value	4.1701e-05 (rank : 130)
Query Neighborhood Hits	395	Target Neighborhood Hits	225	Shared Neighborhood Hits	58
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CYH3_MOUSE
NC score	0.160717 (rank : 327)	θ value	7.1131e-05 (rank : 141)
Query Neighborhood Hits	395	Target Neighborhood Hits	148	Shared Neighborhood Hits	62
SwissProt Accessions	O08967, Q8CI93	Gene names	Pscd3, Grp1
Domain Architecture
Description	Cytohesin-3 (ARF nucleotide-binding site opener 3) (ARNO3 protein) (General receptor of phosphoinositides 1) (Grp1) (CLM-3).

ANKR9_HUMAN
NC score	0.159124 (rank : 328)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	395	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

CYH4_MOUSE
NC score	0.158444 (rank : 329)	θ value	4.1701e-05 (rank : 129)
Query Neighborhood Hits	395	Target Neighborhood Hits	134	Shared Neighborhood Hits	62
SwissProt Accessions	Q80YW0	Gene names	Pscd4
Domain Architecture	No domain graphic available
Description	Cytohesin-4.

DAPP1_HUMAN
NC score	0.156590 (rank : 330)	θ value	0.00020696 (rank : 162)
Query Neighborhood Hits	395	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

CYH4_HUMAN
NC score	0.156075 (rank : 331)	θ value	0.000158464 (rank : 155)
Query Neighborhood Hits	395	Target Neighborhood Hits	135	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UIA0, Q5R3F9, Q9UGT6	Gene names	PSCD4, CYT4
Domain Architecture
Description	Cytohesin-4.

ABTB1_HUMAN
NC score	0.153516 (rank : 332)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	395	Target Neighborhood Hits	325	Shared Neighborhood Hits	151
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

TRPV1_MOUSE
NC score	0.142428 (rank : 333)	θ value	0.47712 (rank : 318)
Query Neighborhood Hits	395	Target Neighborhood Hits	189	Shared Neighborhood Hits	142
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

DGKH_HUMAN
NC score	0.134517 (rank : 334)	θ value	0.000786445 (rank : 196)
Query Neighborhood Hits	395	Target Neighborhood Hits	255	Shared Neighborhood Hits	79
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

TRPV1_HUMAN
NC score	0.134141 (rank : 335)	θ value	1.06291 (rank : 330)
Query Neighborhood Hits	395	Target Neighborhood Hits	184	Shared Neighborhood Hits	137
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

PLEK2_HUMAN
NC score	0.125266 (rank : 336)	θ value	0.0148317 (rank : 254)
Query Neighborhood Hits	395	Target Neighborhood Hits	101	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NYT0, Q96JT0	Gene names	PLEK2
Domain Architecture
Description	Pleckstrin-2.

RHG25_HUMAN
NC score	0.125000 (rank : 337)	θ value	0.47712 (rank : 317)
Query Neighborhood Hits	395	Target Neighborhood Hits	550	Shared Neighborhood Hits	90
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RSNL2_HUMAN
NC score	0.123960 (rank : 338)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	395	Target Neighborhood Hits	136	Shared Neighborhood Hits	106
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

RHG25_MOUSE
NC score	0.123576 (rank : 339)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	395	Target Neighborhood Hits	492	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

TRPV3_HUMAN
NC score	0.121037 (rank : 340)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	395	Target Neighborhood Hits	198	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

DGKD_HUMAN
NC score	0.119925 (rank : 341)	θ value	0.00102713 (rank : 201)
Query Neighborhood Hits	395	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

TRPV3_MOUSE
NC score	0.119828 (rank : 342)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	395	Target Neighborhood Hits	188	Shared Neighborhood Hits	120
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

PLEK_HUMAN
NC score	0.114642 (rank : 343)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	395	Target Neighborhood Hits	110	Shared Neighborhood Hits	49
SwissProt Accessions	P08567, Q53SU8, Q6FGM8, Q8WV81	Gene names	PLEK, P47
Domain Architecture
Description	Pleckstrin (Platelet p47 protein).

PLEK2_MOUSE
NC score	0.114574 (rank : 344)	θ value	0.0736092 (rank : 286)
Query Neighborhood Hits	395	Target Neighborhood Hits	96	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV52	Gene names	Plek2
Domain Architecture
Description	Pleckstrin-2.

SWP70_HUMAN
NC score	0.113274 (rank : 345)	θ value	0.00102713 (rank : 206)
Query Neighborhood Hits	395	Target Neighborhood Hits	973	Shared Neighborhood Hits	108
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.111154 (rank : 346)	θ value	0.00175202 (rank : 215)
Query Neighborhood Hits	395	Target Neighborhood Hits	1097	Shared Neighborhood Hits	111
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CMTA1_HUMAN
NC score	0.109088 (rank : 347)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	395	Target Neighborhood Hits	217	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

PLEK_MOUSE
NC score	0.108064 (rank : 348)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	395	Target Neighborhood Hits	109	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JHK5, Q9ERI9	Gene names	Plek
Domain Architecture
Description	Pleckstrin.

TRPV2_HUMAN
NC score	0.106326 (rank : 349)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	395	Target Neighborhood Hits	130	Shared Neighborhood Hits	103
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

RSNL2_MOUSE
NC score	0.104569 (rank : 350)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	395	Target Neighborhood Hits	129	Shared Neighborhood Hits	91
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

CNKR1_HUMAN
NC score	0.097044 (rank : 351)	θ value	3.0926 (rank : 349)
Query Neighborhood Hits	395	Target Neighborhood Hits	154	Shared Neighborhood Hits	42
SwissProt Accessions	Q969H4, O95381	Gene names	CNKSR1, CNK1
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 1 (Connector enhancer of KSR1) (hCNK1) (Connector enhancer of KSR-like) (CNK homolog protein 1).

CU081_HUMAN
NC score	0.092177 (rank : 352)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	395	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

OSBP1_HUMAN
NC score	0.090906 (rank : 353)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	395	Target Neighborhood Hits	180	Shared Neighborhood Hits	64
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

RASA3_HUMAN
NC score	0.090733 (rank : 354)	θ value	0.00665767 (rank : 242)
Query Neighborhood Hits	395	Target Neighborhood Hits	166	Shared Neighborhood Hits	40
SwissProt Accessions	Q14644	Gene names	RASA3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein).

RBP1_MOUSE
NC score	0.089627 (rank : 355)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	395	Target Neighborhood Hits	493	Shared Neighborhood Hits	49
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

RHG09_HUMAN
NC score	0.089489 (rank : 356)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	395	Target Neighborhood Hits	186	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

CMTA2_HUMAN
NC score	0.089135 (rank : 357)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	395	Target Neighborhood Hits	199	Shared Neighborhood Hits	83
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

RASA3_MOUSE
NC score	0.089069 (rank : 358)	θ value	0.00665767 (rank : 243)
Query Neighborhood Hits	395	Target Neighborhood Hits	144	Shared Neighborhood Hits	37
SwissProt Accessions	Q60790	Gene names	Rasa3
Domain Architecture
Description	Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein) (GapIII).

RBP1_HUMAN
NC score	0.087337 (rank : 359)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	395	Target Neighborhood Hits	521	Shared Neighborhood Hits	48
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

DGKK_HUMAN
NC score	0.086117 (rank : 360)	θ value	0.0961366 (rank : 287)
Query Neighborhood Hits	395	Target Neighborhood Hits	378	Shared Neighborhood Hits	42
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

TCGAP_HUMAN
NC score	0.085518 (rank : 361)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	395	Target Neighborhood Hits	872	Shared Neighborhood Hits	37
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CMTA2_MOUSE
NC score	0.084467 (rank : 362)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	395	Target Neighborhood Hits	216	Shared Neighborhood Hits	75
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ANKF1_HUMAN
NC score	0.082776 (rank : 363)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	395	Target Neighborhood Hits	126	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

RGAP1_MOUSE
NC score	0.080864 (rank : 364)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	395	Target Neighborhood Hits	185	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_HUMAN
NC score	0.079886 (rank : 365)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	395	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CAPS1_MOUSE
NC score	0.079829 (rank : 366)	θ value	0.00228821 (rank : 218)
Query Neighborhood Hits	395	Target Neighborhood Hits	93	Shared Neighborhood Hits	25
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

GAB1_HUMAN
NC score	0.079718 (rank : 367)	θ value	0.62314 (rank : 323)
Query Neighborhood Hits	395	Target Neighborhood Hits	279	Shared Neighborhood Hits	47
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

TRPV2_MOUSE
NC score	0.079575 (rank : 368)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	395	Target Neighborhood Hits	111	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TCGAP_MOUSE
NC score	0.078551 (rank : 369)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	395	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

GMIP_MOUSE
NC score	0.078118 (rank : 370)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	395	Target Neighborhood Hits	202	Shared Neighborhood Hits	18
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CAPS1_HUMAN
NC score	0.077653 (rank : 371)	θ value	0.00228821 (rank : 217)
Query Neighborhood Hits	395	Target Neighborhood Hits	86	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

3BP2_HUMAN
NC score	0.077624 (rank : 372)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	395	Target Neighborhood Hits	296	Shared Neighborhood Hits	42
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

RHG12_MOUSE
NC score	0.077309 (rank : 373)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

CAPS2_MOUSE
NC score	0.076472 (rank : 374)	θ value	0.0252991 (rank : 265)
Query Neighborhood Hits	395	Target Neighborhood Hits	78	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BYR5, O08903, Q66JM7, Q6PCL7, Q76I88, Q7TMM6, Q80ZV8, Q8BL25, Q8BY04, Q8K3K6	Gene names	Cadps2, Caps2
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

RASA2_MOUSE
NC score	0.075526 (rank : 375)	θ value	0.163984 (rank : 294)
Query Neighborhood Hits	395	Target Neighborhood Hits	159	Shared Neighborhood Hits	35
SwissProt Accessions	P58069	Gene names	Rasa2
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

BCR_HUMAN
NC score	0.074344 (rank : 376)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	395	Target Neighborhood Hits	204	Shared Neighborhood Hits	21
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

GAB2_MOUSE
NC score	0.074232 (rank : 377)	θ value	4.03905 (rank : 361)
Query Neighborhood Hits	395	Target Neighborhood Hits	220	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1S8, Q9R1X3	Gene names	Gab2
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (PH domain-containing adaptor molecule p97).

RASA2_HUMAN
NC score	0.074230 (rank : 378)	θ value	0.0961366 (rank : 289)
Query Neighborhood Hits	395	Target Neighborhood Hits	157	Shared Neighborhood Hits	35
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

RHG12_HUMAN
NC score	0.074090 (rank : 379)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	395	Target Neighborhood Hits	190	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

ABR_HUMAN
NC score	0.074028 (rank : 380)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	395	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

GRLF1_HUMAN
NC score	0.073808 (rank : 381)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	395	Target Neighborhood Hits	167	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

GAB2_HUMAN
NC score	0.073784 (rank : 382)	θ value	6.88961 (rank : 374)
Query Neighborhood Hits	395	Target Neighborhood Hits	188	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQC2, O60317	Gene names	GAB2, KIAA0571
Domain Architecture
Description	GRB2-associated-binding protein 2 (GRB2-associated binder 2) (pp100).

MRIP_MOUSE
NC score	0.073278 (rank : 383)	θ value	0.47712 (rank : 316)
Query Neighborhood Hits	395	Target Neighborhood Hits	569	Shared Neighborhood Hits	77
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

GMIP_HUMAN
NC score	0.073229 (rank : 384)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	395	Target Neighborhood Hits	225	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

3BP2_MOUSE
NC score	0.072894 (rank : 385)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	395	Target Neighborhood Hits	142	Shared Neighborhood Hits	39
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

GAB1_MOUSE
NC score	0.072766 (rank : 386)	θ value	0.813845 (rank : 324)
Query Neighborhood Hits	395	Target Neighborhood Hits	233	Shared Neighborhood Hits	46
SwissProt Accessions	Q9QYY0, Q91VW7	Gene names	Gab1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

CAPS2_HUMAN
NC score	0.072579 (rank : 387)	θ value	0.125558 (rank : 291)
Query Neighborhood Hits	395	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q86UW7, Q658Q2, Q7Z5T7, Q8IZW9, Q8N7M4, Q9H6P4, Q9HCI1, Q9NWK8	Gene names	CADPS2, CAPS2, KIAA1591
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 2 (Calcium-dependent activator protein for secretion 2) (CAPS-2).

CNKR2_MOUSE
NC score	0.072362 (rank : 388)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	395	Target Neighborhood Hits	197	Shared Neighborhood Hits	51
SwissProt Accessions	Q80YA9, Q80TP2	Gene names	Cnksr2, Kiaa0902
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

CNKR2_HUMAN
NC score	0.072160 (rank : 389)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	395	Target Neighborhood Hits	197	Shared Neighborhood Hits	49
SwissProt Accessions	Q8WXI2, O94976, Q8WXI1	Gene names	CNKSR2, CNK2, KIAA0902, KSR2
Domain Architecture	No domain graphic available
Description	Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR2) (CNK2).

PKHB2_MOUSE
NC score	0.072121 (rank : 390)	θ value	6.88961 (rank : 381)
Query Neighborhood Hits	395	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QZC7, Q3UDH6, Q8C4I4, Q8CA27	Gene names	Plekhb2, Evt2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

RHG05_HUMAN
NC score	0.071710 (rank : 391)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	395	Target Neighborhood Hits	158	Shared Neighborhood Hits	10
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

FGD4_MOUSE
NC score	0.071600 (rank : 392)	θ value	1.38821 (rank : 334)
Query Neighborhood Hits	395	Target Neighborhood Hits	227	Shared Neighborhood Hits	46
SwissProt Accessions	Q91ZT5, Q3UEB6, Q8BW60, Q8BZI7, Q91ZT3, Q91ZT4	Gene names	Fgd4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein).

TARA_MOUSE
NC score	0.071437 (rank : 393)	θ value	0.365318 (rank : 311)
Query Neighborhood Hits	395	Target Neighborhood Hits	1133	Shared Neighborhood Hits	93
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CHIO_MOUSE
NC score	0.071417 (rank : 394)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	395	Target Neighborhood Hits	130	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

PSD3_HUMAN
NC score	0.071318 (rank : 395)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	395	Target Neighborhood Hits	75	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NYI0, Q9Y2F1	Gene names	PSD3, EFA6R, HCA67, KIAA0942
Domain Architecture
Description	PH and SEC7 domain-containing protein 3 (Pleckstrin homology and SEC7 domain-containing protein 3) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Hepatocellular carcinoma- associated antigen 67).

RHG05_MOUSE
NC score	0.071168 (rank : 396)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	395	Target Neighborhood Hits	165	Shared Neighborhood Hits	10
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG18_HUMAN
NC score	0.070503 (rank : 397)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	395	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

OSBL9_HUMAN
NC score	0.069974 (rank : 398)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	395	Target Neighborhood Hits	138	Shared Neighborhood Hits	51
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

ANLN_HUMAN
NC score	0.069796 (rank : 399)	θ value	1.06291 (rank : 325)
Query Neighborhood Hits	395	Target Neighborhood Hits	222	Shared Neighborhood Hits	36
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CHIN_HUMAN
NC score	0.069113 (rank : 400)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	395	Target Neighborhood Hits	227	Shared Neighborhood Hits	13
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
NC score	0.069064 (rank : 401)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	395	Target Neighborhood Hits	229	Shared Neighborhood Hits	13
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.068844 (rank : 402)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	395	Target Neighborhood Hits	220	Shared Neighborhood Hits	13
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

FGD1_HUMAN
NC score	0.068676 (rank : 403)	θ value	0.00869519 (rank : 248)
Query Neighborhood Hits	395	Target Neighborhood Hits	367	Shared Neighborhood Hits	44
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

RHG06_HUMAN
NC score	0.068330 (rank : 404)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	395	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

3BP1_HUMAN
NC score	0.068085 (rank : 405)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	395	Target Neighborhood Hits	376	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG06_MOUSE
NC score	0.068047 (rank : 406)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	395	Target Neighborhood Hits	105	Shared Neighborhood Hits	9
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG18_MOUSE
NC score	0.066946 (rank : 407)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	395	Target Neighborhood Hits	110	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

ANLN_MOUSE
NC score	0.066790 (rank : 408)	θ value	1.38821 (rank : 332)
Query Neighborhood Hits	395	Target Neighborhood Hits	297	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

3BP1_MOUSE
NC score	0.066084 (rank : 409)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	395	Target Neighborhood Hits	238	Shared Neighborhood Hits	23
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MRIP_HUMAN
NC score	0.065775 (rank : 410)	θ value	5.27518 (rank : 369)
Query Neighborhood Hits	395	Target Neighborhood Hits	578	Shared Neighborhood Hits	76
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

PHLB2_MOUSE
NC score	0.065437 (rank : 411)	θ value	3.0926 (rank : 354)
Query Neighborhood Hits	395	Target Neighborhood Hits	1016	Shared Neighborhood Hits	85
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

FGD1_MOUSE
NC score	0.065375 (rank : 412)	θ value	0.0736092 (rank : 285)
Query Neighborhood Hits	395	Target Neighborhood Hits	387	Shared Neighborhood Hits	41
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

OSBL3_HUMAN
NC score	0.064954 (rank : 413)	θ value	1.81305 (rank : 340)
Query Neighborhood Hits	395	Target Neighborhood Hits	93	Shared Neighborhood Hits	43
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

PKHB2_HUMAN
NC score	0.064287 (rank : 414)	θ value	1.81305 (rank : 341)
Query Neighborhood Hits	395	Target Neighborhood Hits	54	Shared Neighborhood Hits	34
SwissProt Accessions	Q96CS7, Q86W37, Q9BV75, Q9NWK1	Gene names	PLEKHB2, EVT2
Domain Architecture
Description	Pleckstrin homology domain-containing family B member 2 (Evectin-2).

OSBL3_MOUSE
NC score	0.063994 (rank : 415)	θ value	3.0926 (rank : 353)
Query Neighborhood Hits	395	Target Neighborhood Hits	86	Shared Neighborhood Hits	42
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

TARA_HUMAN
NC score	0.063834 (rank : 416)	θ value	0.365318 (rank : 310)
Query Neighborhood Hits	395	Target Neighborhood Hits	1626	Shared Neighborhood Hits	104
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TAGAP_HUMAN
NC score	0.063215 (rank : 417)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	395	Target Neighborhood Hits	82	Shared Neighborhood Hits	9
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

FNBP2_HUMAN
NC score	0.063195 (rank : 418)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	395	Target Neighborhood Hits	432	Shared Neighborhood Hits	36
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

SRGP2_HUMAN
NC score	0.062281 (rank : 419)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	395	Target Neighborhood Hits	331	Shared Neighborhood Hits	30
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

OSBP2_HUMAN
NC score	0.062206 (rank : 420)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	395	Target Neighborhood Hits	154	Shared Neighborhood Hits	51
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

SRGP2_MOUSE
NC score	0.061911 (rank : 421)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	395	Target Neighborhood Hits	324	Shared Neighborhood Hits	33
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP1_HUMAN
NC score	0.061436 (rank : 422)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	395	Target Neighborhood Hits	390	Shared Neighborhood Hits	34
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

BIG2_HUMAN
NC score	0.060713 (rank : 423)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	395	Target Neighborhood Hits	66	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6D5, Q5TFT9, Q9NTS1	Gene names	ARFGEF2, ARFGEP2, BIG2
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2).

RHG04_HUMAN
NC score	0.060509 (rank : 424)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	395	Target Neighborhood Hits	307	Shared Neighborhood Hits	22
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

FGD4_HUMAN
NC score	0.060503 (rank : 425)	θ value	0.62314 (rank : 322)
Query Neighborhood Hits	395	Target Neighborhood Hits	219	Shared Neighborhood Hits	50
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

PHLB2_HUMAN
NC score	0.060472 (rank : 426)	θ value	5.27518 (rank : 370)
Query Neighborhood Hits	395	Target Neighborhood Hits	964	Shared Neighborhood Hits	80
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

GBF1_HUMAN
NC score	0.060317 (rank : 427)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	395	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

BIG1_HUMAN
NC score	0.059469 (rank : 428)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	395	Target Neighborhood Hits	76	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y6D6, Q9NV46, Q9UFV2, Q9UNL0	Gene names	ARFGEF1, ARFGEP1, BIG1
Domain Architecture
Description	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Brefeldin A-inhibited GEP 1) (p200 ARF-GEP1) (p200 ARF guanine nucleotide exchange factor).

TRPV4_HUMAN
NC score	0.059431 (rank : 429)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	395	Target Neighborhood Hits	150	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

RHG01_HUMAN
NC score	0.059305 (rank : 430)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	395	Target Neighborhood Hits	75	Shared Neighborhood Hits	9
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

IQEC3_MOUSE
NC score	0.058026 (rank : 431)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	395	Target Neighborhood Hits	274	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TES0, Q3UHP8, Q80TJ8	Gene names	Iqsec3, Kiaa1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

TAGAP_MOUSE
NC score	0.057313 (rank : 432)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	395	Target Neighborhood Hits	83	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

C43BP_MOUSE
NC score	0.056869 (rank : 433)	θ value	8.99809 (rank : 386)
Query Neighborhood Hits	395	Target Neighborhood Hits	91	Shared Neighborhood Hits	45
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

MYO10_HUMAN
NC score	0.056867 (rank : 434)	θ value	4.03905 (rank : 362)
Query Neighborhood Hits	395	Target Neighborhood Hits	920	Shared Neighborhood Hits	106
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

PSD4_HUMAN
NC score	0.056805 (rank : 435)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	395	Target Neighborhood Hits	178	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NDX1, O95621, Q4ZG34, Q6GPH8, Q8IYP4	Gene names	PSD4, EFA6B, TIC
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B) (Telomeric of interleukin-1 cluster protein).

PHLB1_MOUSE
NC score	0.056655 (rank : 436)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	395	Target Neighborhood Hits	678	Shared Neighborhood Hits	80
SwissProt Accessions	Q6PDH0, Q80TV2	Gene names	Phldb1, Kiaa0638, Ll5a
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

PSD4_MOUSE
NC score	0.055868 (rank : 437)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	395	Target Neighborhood Hits	78	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BLR5, Q3TE33, Q3TQF5, Q3UD59, Q3UFH9, Q80V44	Gene names	Psd4
Domain Architecture	No domain graphic available
Description	PH and SEC7 domain-containing protein 4 (Pleckstrin homology and SEC7 domain-containing protein 4).

FBX8_MOUSE
NC score	0.055144 (rank : 438)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	395	Target Neighborhood Hits	45	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QZN3	Gene names	Fbxo8, Fbx8
Domain Architecture
Description	F-box only protein 8.

IQEC1_HUMAN
NC score	0.055140 (rank : 439)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	395	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q6DN90, O94863, Q96D85	Gene names	IQSEC1, ARFGEP100, BRAG2, KIAA0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein).

OSBP2_MOUSE
NC score	0.055098 (rank : 440)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	395	Target Neighborhood Hits	150	Shared Neighborhood Hits	50
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

FBX8_HUMAN
NC score	0.054903 (rank : 441)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	395	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NRD0, Q6UWN4, Q9NRP5, Q9UKC4	Gene names	FBXO8, FBS, FBX8
Domain Architecture
Description	F-box only protein 8 (F-box/SEC7 protein FBS).

PHLB1_HUMAN
NC score	0.054320 (rank : 442)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	395	Target Neighborhood Hits	1038	Shared Neighborhood Hits	93
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

IQEC1_MOUSE
NC score	0.054249 (rank : 443)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	395	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R0S2, Q3TZC3, Q5DU15	Gene names	Iqsec1, Kiaa0763
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 1.

IQEC3_HUMAN
NC score	0.053594 (rank : 444)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	395	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPP2, Q8TB43	Gene names	IQSEC3, KIAA1110
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 3.

CE005_HUMAN
NC score	0.053581 (rank : 445)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	395	Target Neighborhood Hits	213	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

TRPV4_MOUSE
NC score	0.053441 (rank : 446)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	395	Target Neighborhood Hits	117	Shared Neighborhood Hits	68
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC6_HUMAN
NC score	0.053013 (rank : 447)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	395	Target Neighborhood Hits	171	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

RHG08_MOUSE
NC score	0.051807 (rank : 448)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	395	Target Neighborhood Hits	73	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

CE005_MOUSE
NC score	0.051463 (rank : 449)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	395	Target Neighborhood Hits	238	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG08_HUMAN
NC score	0.051392 (rank : 450)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	395	Target Neighborhood Hits	88	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

IQEC2_MOUSE
NC score	0.050859 (rank : 451)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	395	Target Neighborhood Hits	417	Shared Neighborhood Hits	26
SwissProt Accessions	Q5DU25	Gene names	Iqsec2, Kiaa0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

IQEC2_HUMAN
NC score	0.050600 (rank : 452)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	395	Target Neighborhood Hits	403	Shared Neighborhood Hits	25
SwissProt Accessions	Q5JU85, O60275	Gene names	IQSEC2, KIAA0522
Domain Architecture	No domain graphic available
Description	IQ motif and Sec7 domain-containing protein 2.

TBCD2_HUMAN
NC score	0.050596 (rank : 453)	θ value	0.279714 (rank : 303)
Query Neighborhood Hits	395	Target Neighborhood Hits	419	Shared Neighborhood Hits	58
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

RHG07_MOUSE
NC score	0.050458 (rank : 454)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	395	Target Neighborhood Hits	103	Shared Neighborhood Hits	11
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RASA1_HUMAN
NC score	0.050177 (rank : 455)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	395	Target Neighborhood Hits	258	Shared Neighborhood Hits	38
SwissProt Accessions	P20936	Gene names	RASA1, RASA
Domain Architecture
Description	Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP).

C43BP_HUMAN
NC score	0.050097 (rank : 456)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	395	Target Neighborhood Hits	87	Shared Neighborhood Hits	44
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

FARP1_HUMAN
NC score	0.047572 (rank : 457)	θ value	5.27518 (rank : 367)
Query Neighborhood Hits	395	Target Neighborhood Hits	241	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Y4F1, Q6IQ29	Gene names	FARP1, CDEP
Domain Architecture	No domain graphic available
Description	FERM, RhoGEF and pleckstrin domain-containing protein 1 (Chondrocyte- derived ezrin-like protein).

EEA1_HUMAN
NC score	0.045288 (rank : 458)	θ value	1.81305 (rank : 337)
Query Neighborhood Hits	395	Target Neighborhood Hits	1796	Shared Neighborhood Hits	94
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FGD3_MOUSE
NC score	0.045138 (rank : 459)	θ value	0.0113563 (rank : 251)
Query Neighborhood Hits	395	Target Neighborhood Hits	257	Shared Neighborhood Hits	27
SwissProt Accessions	O88842, Q8BQ72	Gene names	Fgd3
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3.

OSBL8_HUMAN
NC score	0.043451 (rank : 460)	θ value	0.279714 (rank : 302)
Query Neighborhood Hits	395	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL7_HUMAN
NC score	0.042971 (rank : 461)	θ value	6.88961 (rank : 380)
Query Neighborhood Hits	395	Target Neighborhood Hits	71	Shared Neighborhood Hits	27
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL6_HUMAN
NC score	0.042899 (rank : 462)	θ value	6.88961 (rank : 378)
Query Neighborhood Hits	395	Target Neighborhood Hits	101	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
NC score	0.042893 (rank : 463)	θ value	6.88961 (rank : 379)
Query Neighborhood Hits	395	Target Neighborhood Hits	105	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

FGD2_MOUSE
NC score	0.041706 (rank : 464)	θ value	4.03905 (rank : 360)
Query Neighborhood Hits	395	Target Neighborhood Hits	163	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BY35, O88841, Q7TSE3, Q8VDH4	Gene names	Fgd2
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2.

GOGA4_HUMAN
NC score	0.041604 (rank : 465)	θ value	0.0961366 (rank : 288)
Query Neighborhood Hits	395	Target Neighborhood Hits	2034	Shared Neighborhood Hits	90
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGA5_MOUSE
NC score	0.040517 (rank : 466)	θ value	1.06291 (rank : 329)
Query Neighborhood Hits	395	Target Neighborhood Hits	1434	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CCD46_MOUSE
NC score	0.039988 (rank : 467)	θ value	0.47712 (rank : 313)
Query Neighborhood Hits	395	Target Neighborhood Hits	1405	Shared Neighborhood Hits	71
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CP250_MOUSE
NC score	0.039896 (rank : 468)	θ value	8.99809 (rank : 387)
Query Neighborhood Hits	395	Target Neighborhood Hits	1583	Shared Neighborhood Hits	85
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

FGD2_HUMAN
NC score	0.039875 (rank : 469)	θ value	0.365318 (rank : 309)
Query Neighborhood Hits	395	Target Neighborhood Hits	151	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z6J4, Q5T8I1, Q6P6A8, Q6ZNL5, Q8IZ32, Q8N868, Q9H7M2	Gene names	FGD2, ZFYVE4
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4).

RBP24_HUMAN
NC score	0.039804 (rank : 470)	θ value	1.81305 (rank : 342)
Query Neighborhood Hits	395	Target Neighborhood Hits	1559	Shared Neighborhood Hits	78
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.039741 (rank : 471)	θ value	1.81305 (rank : 338)
Query Neighborhood Hits	395	Target Neighborhood Hits	1558	Shared Neighborhood Hits	78
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA2_MOUSE
NC score	0.037938 (rank : 472)	θ value	0.21417 (rank : 297)
Query Neighborhood Hits	395	Target Neighborhood Hits	944	Shared Neighborhood Hits	57
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

KTN1_MOUSE
NC score	0.035909 (rank : 473)	θ value	8.99809 (rank : 388)
Query Neighborhood Hits	395	Target Neighborhood Hits	1324	Shared Neighborhood Hits	69
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

EZH2_HUMAN
NC score	0.035757 (rank : 474)	θ value	0.47712 (rank : 315)
Query Neighborhood Hits	395	Target Neighborhood Hits	84	Shared Neighborhood Hits	13
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.034774 (rank : 475)	θ value	1.06291 (rank : 328)
Query Neighborhood Hits	395	Target Neighborhood Hits	86	Shared Neighborhood Hits	14
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

FGD3_HUMAN
NC score	0.034385 (rank : 476)	θ value	3.0926 (rank : 350)
Query Neighborhood Hits	395	Target Neighborhood Hits	249	Shared Neighborhood Hits	20
SwissProt Accessions	Q5JSP0, Q7Z7D9, Q8N5G1	Gene names	FGD3, ZFYVE5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 3 (Zinc finger FYVE domain-containing protein 5).

SETB2_HUMAN
NC score	0.032717 (rank : 477)	θ value	8.99809 (rank : 392)
Query Neighborhood Hits	395	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SM1L2_HUMAN
NC score	0.031089 (rank : 478)	θ value	8.99809 (rank : 394)
Query Neighborhood Hits	395	Target Neighborhood Hits	1019	Shared Neighborhood Hits	58
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC3_MOUSE
NC score	0.028236 (rank : 479)	θ value	4.03905 (rank : 364)
Query Neighborhood Hits	395	Target Neighborhood Hits	1187	Shared Neighborhood Hits	60
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.028162 (rank : 480)	θ value	4.03905 (rank : 363)
Query Neighborhood Hits	395	Target Neighborhood Hits	1186	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

MRE11_HUMAN
NC score	0.028041 (rank : 481)	θ value	0.279714 (rank : 301)
Query Neighborhood Hits	395	Target Neighborhood Hits	95	Shared Neighborhood Hits	10
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

MYH11_MOUSE
NC score	0.027914 (rank : 482)	θ value	6.88961 (rank : 377)
Query Neighborhood Hits	395	Target Neighborhood Hits	1777	Shared Neighborhood Hits	89
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
NC score	0.027016 (rank : 483)	θ value	3.0926 (rank : 352)
Query Neighborhood Hits	395	Target Neighborhood Hits	1829	Shared Neighborhood Hits	92
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_HUMAN
NC score	0.026962 (rank : 484)	θ value	2.36792 (rank : 347)
Query Neighborhood Hits	395	Target Neighborhood Hits	1762	Shared Neighborhood Hits	87
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

SKIL_MOUSE
NC score	0.025085 (rank : 485)	θ value	8.99809 (rank : 393)
Query Neighborhood Hits	395	Target Neighborhood Hits	719	Shared Neighborhood Hits	47
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

MRE11_MOUSE
NC score	0.024065 (rank : 486)	θ value	3.0926 (rank : 351)
Query Neighborhood Hits	395	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q61216, Q62430	Gene names	Mre11a, Mre11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A) (MmMRE11A).

ZCHC6_MOUSE
NC score	0.022985 (rank : 487)	θ value	0.279714 (rank : 304)
Query Neighborhood Hits	395	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q5BLK4, Q8CIH3	Gene names	Zcchc6
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

MYH14_MOUSE
NC score	0.022824 (rank : 488)	θ value	8.99809 (rank : 389)
Query Neighborhood Hits	395	Target Neighborhood Hits	1225	Shared Neighborhood Hits	77
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PLEC1_HUMAN
NC score	0.022045 (rank : 489)	θ value	5.27518 (rank : 371)
Query Neighborhood Hits	395	Target Neighborhood Hits	1326	Shared Neighborhood Hits	70
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SPTB2_MOUSE
NC score	0.020867 (rank : 490)	θ value	8.99809 (rank : 395)
Query Neighborhood Hits	395	Target Neighborhood Hits	770	Shared Neighborhood Hits	59
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

DYHC_HUMAN
NC score	0.020097 (rank : 491)	θ value	4.03905 (rank : 358)
Query Neighborhood Hits	395	Target Neighborhood Hits	733	Shared Neighborhood Hits	42
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.020091 (rank : 492)	θ value	4.03905 (rank : 359)
Query Neighborhood Hits	395	Target Neighborhood Hits	729	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

ZCHC6_HUMAN
NC score	0.019525 (rank : 493)	θ value	1.81305 (rank : 343)
Query Neighborhood Hits	395	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	Q5VYS8, Q5H9T0, Q5VYS5, Q5VYS7, Q658Z9, Q659A2, Q6MZJ3, Q8N5F0, Q96N57, Q96NE8, Q9C0F2, Q9H8M6	Gene names	ZCCHC6, KIAA1711
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 6.

PLD1_MOUSE
NC score	0.013097 (rank : 494)	θ value	8.99809 (rank : 391)
Query Neighborhood Hits	395	Target Neighborhood Hits	23	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z280, O35911	Gene names	Pld1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (mPLD1).

GFAP_MOUSE
NC score	0.012931 (rank : 495)	θ value	6.88961 (rank : 375)
Query Neighborhood Hits	395	Target Neighborhood Hits	725	Shared Neighborhood Hits	53
SwissProt Accessions	P03995, Q7TQ30, Q925K3	Gene names	Gfap
Domain Architecture
Description	Glial fibrillary acidic protein, astrocyte (GFAP).

DAAM1_HUMAN
NC score	0.012819 (rank : 496)	θ value	5.27518 (rank : 366)
Query Neighborhood Hits	395	Target Neighborhood Hits	483	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y4D1, Q86U34, Q8N1Z8, Q8TB39	Gene names	DAAM1, KIAA0666
Domain Architecture
Description	Disheveled-associated activator of morphogenesis 1.

PLD1_HUMAN
NC score	0.012459 (rank : 497)	θ value	8.99809 (rank : 390)
Query Neighborhood Hits	395	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q13393	Gene names	PLD1
Domain Architecture
Description	Phospholipase D1 (EC 3.1.4.4) (PLD 1) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1) (hPLD1).

DJC17_MOUSE
NC score	0.009887 (rank : 498)	θ value	1.81305 (rank : 336)
Query Neighborhood Hits	395	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	Q91WT4, Q8C5R1	Gene names	Dnajc17
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 17.

KI13A_MOUSE
NC score	0.005208 (rank : 499)	θ value	1.81305 (rank : 339)
Query Neighborhood Hits	395	Target Neighborhood Hits	395	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

ARBK1_HUMAN
NC score	0.004510 (rank : 500)	θ value	2.36792 (rank : 345)
Query Neighborhood Hits	395	Target Neighborhood Hits	859	Shared Neighborhood Hits	23
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

APLP2_HUMAN
NC score	0.004294 (rank : 501)	θ value	6.88961 (rank : 372)
Query Neighborhood Hits	395	Target Neighborhood Hits	193	Shared Neighborhood Hits	17
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

KIF1A_MOUSE
NC score	0.003309 (rank : 502)	θ value	5.27518 (rank : 368)
Query Neighborhood Hits	395	Target Neighborhood Hits	239	Shared Neighborhood Hits	21
SwissProt Accessions	P33173, Q61770	Gene names	Kif1a, Atsv, Kif1
Domain Architecture
Description	Kinesin-like protein KIF1A (Axonal transporter of synaptic vesicles).

ARBK1_MOUSE
NC score	0.003067 (rank : 503)	θ value	6.88961 (rank : 373)
Query Neighborhood Hits	395	Target Neighborhood Hits	849	Shared Neighborhood Hits	23
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

GNAS1_HUMAN
NC score	0.001408 (rank : 504)	θ value	6.88961 (rank : 376)
Query Neighborhood Hits	395	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q5JWF2, O75684, O75685, Q5JW67, Q5JWF1, Q9NY42	Gene names	GNAS, GNAS1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

SEM3E_MOUSE
NC score	0.000271 (rank : 505)	θ value	3.0926 (rank : 355)
Query Neighborhood Hits	395	Target Neighborhood Hits	76	Shared Neighborhood Hits	2
SwissProt Accessions	P70275, O09078, O09079	Gene names	Sema3e, Semah, Semh
Domain Architecture
Description	Semaphorin-3E precursor (Semaphorin H) (Sema H).