Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : OSBL1_HUMAN

For an explanation of this page, click here

OSBL1_HUMAN
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

OSBL1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	368	Target Neighborhood Hits	368	Shared Neighborhood Hits	368
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
θ value	0 (rank : 2)	NC score	0.995068 (rank : 2)
Query Neighborhood Hits	368	Target Neighborhood Hits	336	Shared Neighborhood Hits	310
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL2_HUMAN
θ value	1.23183e-182 (rank : 3)	NC score	0.676232 (rank : 74)
Query Neighborhood Hits	368	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBL2_MOUSE
θ value	1.36195e-181 (rank : 4)	NC score	0.676486 (rank : 72)
Query Neighborhood Hits	368	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

OSBP2_HUMAN
θ value	1.35324e-88 (rank : 5)	NC score	0.626779 (rank : 138)
Query Neighborhood Hits	368	Target Neighborhood Hits	154	Shared Neighborhood Hits	30
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

OSBP2_MOUSE
θ value	2.38869e-85 (rank : 6)	NC score	0.626172 (rank : 140)
Query Neighborhood Hits	368	Target Neighborhood Hits	150	Shared Neighborhood Hits	30
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBP1_HUMAN
θ value	7.19216e-82 (rank : 7)	NC score	0.623133 (rank : 142)
Query Neighborhood Hits	368	Target Neighborhood Hits	180	Shared Neighborhood Hits	42
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL7_HUMAN
θ value	1.11217e-74 (rank : 8)	NC score	0.632773 (rank : 134)
Query Neighborhood Hits	368	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

OSBL6_HUMAN
θ value	3.57772e-73 (rank : 9)	NC score	0.623126 (rank : 143)
Query Neighborhood Hits	368	Target Neighborhood Hits	101	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_HUMAN
θ value	7.97034e-73 (rank : 10)	NC score	0.620600 (rank : 145)
Query Neighborhood Hits	368	Target Neighborhood Hits	93	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_MOUSE
θ value	7.97034e-73 (rank : 11)	NC score	0.620517 (rank : 146)
Query Neighborhood Hits	368	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL3_MOUSE
θ value	5.1662e-72 (rank : 12)	NC score	0.624015 (rank : 141)
Query Neighborhood Hits	368	Target Neighborhood Hits	86	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL8_HUMAN
θ value	7.29293e-34 (rank : 13)	NC score	0.512865 (rank : 205)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

OSBL5_HUMAN
θ value	3.17079e-29 (rank : 14)	NC score	0.522859 (rank : 202)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
θ value	5.40856e-29 (rank : 15)	NC score	0.521187 (rank : 203)
Query Neighborhood Hits	368	Target Neighborhood Hits	77	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

OSB11_MOUSE
θ value	1.80048e-24 (rank : 16)	NC score	0.489649 (rank : 215)
Query Neighborhood Hits	368	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

OSB10_HUMAN
θ value	3.39556e-23 (rank : 17)	NC score	0.503569 (rank : 210)
Query Neighborhood Hits	368	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL9_HUMAN
θ value	4.43474e-23 (rank : 18)	NC score	0.503386 (rank : 211)
Query Neighborhood Hits	368	Target Neighborhood Hits	138	Shared Neighborhood Hits	38
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

OSB11_HUMAN
θ value	8.36355e-22 (rank : 19)	NC score	0.482895 (rank : 218)
Query Neighborhood Hits	368	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

TNKS2_HUMAN
θ value	1.2077e-20 (rank : 20)	NC score	0.714685 (rank : 9)
Query Neighborhood Hits	368	Target Neighborhood Hits	361	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
θ value	5.99374e-20 (rank : 21)	NC score	0.710683 (rank : 10)
Query Neighborhood Hits	368	Target Neighborhood Hits	477	Shared Neighborhood Hits	284
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ANK2_HUMAN
θ value	1.63225e-17 (rank : 22)	NC score	0.649679 (rank : 124)
Query Neighborhood Hits	368	Target Neighborhood Hits	1615	Shared Neighborhood Hits	306
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANK3_HUMAN
θ value	2.7842e-17 (rank : 23)	NC score	0.692009 (rank : 41)
Query Neighborhood Hits	368	Target Neighborhood Hits	853	Shared Neighborhood Hits	295
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ANR52_MOUSE
θ value	1.38178e-16 (rank : 24)	NC score	0.701947 (rank : 19)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	284
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ASB7_HUMAN
θ value	1.80466e-16 (rank : 25)	NC score	0.718770 (rank : 5)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
θ value	1.80466e-16 (rank : 26)	NC score	0.718708 (rank : 6)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	277
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANK1_HUMAN
θ value	4.02038e-16 (rank : 27)	NC score	0.699799 (rank : 22)
Query Neighborhood Hits	368	Target Neighborhood Hits	416	Shared Neighborhood Hits	285
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

CSKI1_MOUSE
θ value	4.02038e-16 (rank : 28)	NC score	0.660972 (rank : 102)
Query Neighborhood Hits	368	Target Neighborhood Hits	1031	Shared Neighborhood Hits	281
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANR44_HUMAN
θ value	5.25075e-16 (rank : 29)	NC score	0.707797 (rank : 14)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	282
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

CSKI1_HUMAN
θ value	5.25075e-16 (rank : 30)	NC score	0.661490 (rank : 99)
Query Neighborhood Hits	368	Target Neighborhood Hits	997	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ANK1_MOUSE
θ value	6.85773e-16 (rank : 31)	NC score	0.698916 (rank : 24)
Query Neighborhood Hits	368	Target Neighborhood Hits	430	Shared Neighborhood Hits	287
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

MIB1_HUMAN
θ value	3.40345e-15 (rank : 32)	NC score	0.682461 (rank : 64)
Query Neighborhood Hits	368	Target Neighborhood Hits	470	Shared Neighborhood Hits	281
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
θ value	3.40345e-15 (rank : 33)	NC score	0.682062 (rank : 65)
Query Neighborhood Hits	368	Target Neighborhood Hits	471	Shared Neighborhood Hits	281
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

PSD10_HUMAN
θ value	3.40345e-15 (rank : 34)	NC score	0.733429 (rank : 3)
Query Neighborhood Hits	368	Target Neighborhood Hits	301	Shared Neighborhood Hits	280
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR28_MOUSE
θ value	5.8054e-15 (rank : 35)	NC score	0.705619 (rank : 16)
Query Neighborhood Hits	368	Target Neighborhood Hits	314	Shared Neighborhood Hits	284
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ASB3_HUMAN
θ value	7.58209e-15 (rank : 36)	NC score	0.710206 (rank : 11)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKR6_HUMAN
θ value	9.90251e-15 (rank : 37)	NC score	0.715467 (rank : 7)
Query Neighborhood Hits	368	Target Neighborhood Hits	439	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR28_HUMAN
θ value	9.90251e-15 (rank : 38)	NC score	0.704120 (rank : 18)
Query Neighborhood Hits	368	Target Neighborhood Hits	314	Shared Neighborhood Hits	283
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_HUMAN
θ value	9.90251e-15 (rank : 39)	NC score	0.700628 (rank : 20)
Query Neighborhood Hits	368	Target Neighborhood Hits	322	Shared Neighborhood Hits	284
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANKS1_HUMAN
θ value	1.68911e-14 (rank : 40)	NC score	0.683884 (rank : 62)
Query Neighborhood Hits	368	Target Neighborhood Hits	438	Shared Neighborhood Hits	282
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

PSD10_MOUSE
θ value	6.41864e-14 (rank : 41)	NC score	0.732360 (rank : 4)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	278
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ANR50_HUMAN
θ value	8.38298e-14 (rank : 42)	NC score	0.709882 (rank : 12)
Query Neighborhood Hits	368	Target Neighborhood Hits	361	Shared Neighborhood Hits	283
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ASB3_MOUSE
θ value	1.42992e-13 (rank : 43)	NC score	0.708562 (rank : 13)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANKS1_MOUSE
θ value	2.43908e-13 (rank : 44)	NC score	0.673248 (rank : 77)
Query Neighborhood Hits	368	Target Neighborhood Hits	453	Shared Neighborhood Hits	281
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

PP16A_HUMAN
θ value	4.16044e-13 (rank : 45)	NC score	0.691244 (rank : 44)
Query Neighborhood Hits	368	Target Neighborhood Hits	340	Shared Neighborhood Hits	275
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

PP16B_MOUSE
θ value	4.16044e-13 (rank : 46)	NC score	0.685716 (rank : 59)
Query Neighborhood Hits	368	Target Neighborhood Hits	302	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

TNI3K_MOUSE
θ value	4.16044e-13 (rank : 47)	NC score	0.355568 (rank : 267)
Query Neighborhood Hits	368	Target Neighborhood Hits	1079	Shared Neighborhood Hits	288
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

PP16B_HUMAN
θ value	5.43371e-13 (rank : 48)	NC score	0.687258 (rank : 52)
Query Neighborhood Hits	368	Target Neighborhood Hits	307	Shared Neighborhood Hits	277
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

MYPT2_HUMAN
θ value	9.26847e-13 (rank : 49)	NC score	0.681872 (rank : 66)
Query Neighborhood Hits	368	Target Neighborhood Hits	707	Shared Neighborhood Hits	301
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANKK1_HUMAN
θ value	1.2105e-12 (rank : 50)	NC score	0.453634 (rank : 226)
Query Neighborhood Hits	368	Target Neighborhood Hits	1075	Shared Neighborhood Hits	286
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

PP16A_MOUSE
θ value	1.2105e-12 (rank : 51)	NC score	0.693119 (rank : 39)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	277
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

ANR12_HUMAN
θ value	1.58096e-12 (rank : 52)	NC score	0.607076 (rank : 162)
Query Neighborhood Hits	368	Target Neighborhood Hits	1081	Shared Neighborhood Hits	307
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANKK1_MOUSE
θ value	2.0648e-12 (rank : 53)	NC score	0.440662 (rank : 232)
Query Neighborhood Hits	368	Target Neighborhood Hits	1072	Shared Neighborhood Hits	285
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

BARD1_HUMAN
θ value	2.69671e-12 (rank : 54)	NC score	0.673894 (rank : 76)
Query Neighborhood Hits	368	Target Neighborhood Hits	427	Shared Neighborhood Hits	276
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

MIB2_HUMAN
θ value	2.69671e-12 (rank : 55)	NC score	0.669958 (rank : 81)
Query Neighborhood Hits	368	Target Neighborhood Hits	438	Shared Neighborhood Hits	276
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

ANR11_HUMAN
θ value	3.52202e-12 (rank : 56)	NC score	0.629238 (rank : 136)
Query Neighborhood Hits	368	Target Neighborhood Hits	1289	Shared Neighborhood Hits	297
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

BCOR_HUMAN
θ value	6.00763e-12 (rank : 57)	NC score	0.608218 (rank : 160)
Query Neighborhood Hits	368	Target Neighborhood Hits	609	Shared Neighborhood Hits	271
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

INVS_HUMAN
θ value	6.00763e-12 (rank : 58)	NC score	0.697852 (rank : 26)
Query Neighborhood Hits	368	Target Neighborhood Hits	455	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

BCOR_MOUSE
θ value	7.84624e-12 (rank : 59)	NC score	0.616012 (rank : 150)
Query Neighborhood Hits	368	Target Neighborhood Hits	521	Shared Neighborhood Hits	270
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ILK_MOUSE
θ value	7.84624e-12 (rank : 60)	NC score	0.424443 (rank : 243)
Query Neighborhood Hits	368	Target Neighborhood Hits	858	Shared Neighborhood Hits	272
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

PA2G6_HUMAN
θ value	1.02475e-11 (rank : 61)	NC score	0.689264 (rank : 49)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	270
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

ANR42_HUMAN
θ value	1.33837e-11 (rank : 62)	NC score	0.706565 (rank : 15)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	271
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

INVS_MOUSE
θ value	1.74796e-11 (rank : 63)	NC score	0.689934 (rank : 47)
Query Neighborhood Hits	368	Target Neighborhood Hits	609	Shared Neighborhood Hits	281
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

BARD1_MOUSE
θ value	2.28291e-11 (rank : 64)	NC score	0.669954 (rank : 82)
Query Neighborhood Hits	368	Target Neighborhood Hits	411	Shared Neighborhood Hits	270
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

RAI14_MOUSE
θ value	2.98157e-11 (rank : 65)	NC score	0.496393 (rank : 213)
Query Neighborhood Hits	368	Target Neighborhood Hits	1505	Shared Neighborhood Hits	320
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CSKI2_MOUSE
θ value	3.89403e-11 (rank : 66)	NC score	0.661343 (rank : 100)
Query Neighborhood Hits	368	Target Neighborhood Hits	812	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ILK1_HUMAN
θ value	3.89403e-11 (rank : 67)	NC score	0.424291 (rank : 244)
Query Neighborhood Hits	368	Target Neighborhood Hits	857	Shared Neighborhood Hits	272
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	3.89403e-11 (rank : 68)	NC score	0.439323 (rank : 233)
Query Neighborhood Hits	368	Target Neighborhood Hits	848	Shared Neighborhood Hits	272
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

NFKB1_MOUSE
θ value	3.89403e-11 (rank : 69)	NC score	0.600386 (rank : 167)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	261
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

TNI3K_HUMAN
θ value	3.89403e-11 (rank : 70)	NC score	0.357117 (rank : 266)
Query Neighborhood Hits	368	Target Neighborhood Hits	1084	Shared Neighborhood Hits	287
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

NFKB1_HUMAN
θ value	5.08577e-11 (rank : 71)	NC score	0.600163 (rank : 168)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	266
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

PA2G6_MOUSE
θ value	6.64225e-11 (rank : 72)	NC score	0.693138 (rank : 38)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	272
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

RIPK4_HUMAN
θ value	6.64225e-11 (rank : 73)	NC score	0.444775 (rank : 229)
Query Neighborhood Hits	368	Target Neighborhood Hits	1094	Shared Neighborhood Hits	290
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

CSKI2_HUMAN
θ value	8.67504e-11 (rank : 74)	NC score	0.658821 (rank : 107)
Query Neighborhood Hits	368	Target Neighborhood Hits	747	Shared Neighborhood Hits	281
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

DAPK1_MOUSE
θ value	1.133e-10 (rank : 75)	NC score	0.316936 (rank : 278)
Query Neighborhood Hits	368	Target Neighborhood Hits	1138	Shared Neighborhood Hits	286
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DAPK1_HUMAN
θ value	1.47974e-10 (rank : 76)	NC score	0.310446 (rank : 280)
Query Neighborhood Hits	368	Target Neighborhood Hits	1130	Shared Neighborhood Hits	283
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

EHMT2_HUMAN
θ value	3.29651e-10 (rank : 77)	NC score	0.646123 (rank : 128)
Query Neighborhood Hits	368	Target Neighborhood Hits	498	Shared Neighborhood Hits	287
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ZDH13_HUMAN
θ value	3.29651e-10 (rank : 78)	NC score	0.615686 (rank : 152)
Query Neighborhood Hits	368	Target Neighborhood Hits	322	Shared Neighborhood Hits	270
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ASZ1_MOUSE
θ value	4.30538e-10 (rank : 79)	NC score	0.685928 (rank : 58)
Query Neighborhood Hits	368	Target Neighborhood Hits	319	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

NOTC4_HUMAN
θ value	4.30538e-10 (rank : 80)	NC score	0.375414 (rank : 260)
Query Neighborhood Hits	368	Target Neighborhood Hits	905	Shared Neighborhood Hits	281
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ZDH13_MOUSE
θ value	4.30538e-10 (rank : 81)	NC score	0.613275 (rank : 156)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	272
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

EHMT2_MOUSE
θ value	5.62301e-10 (rank : 82)	NC score	0.632686 (rank : 135)
Query Neighborhood Hits	368	Target Neighborhood Hits	750	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

NOTC4_MOUSE
θ value	7.34386e-10 (rank : 83)	NC score	0.379184 (rank : 258)
Query Neighborhood Hits	368	Target Neighborhood Hits	872	Shared Neighborhood Hits	278
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

ANKR1_HUMAN
θ value	9.59137e-10 (rank : 84)	NC score	0.695581 (rank : 32)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	272
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ASZ1_HUMAN
θ value	9.59137e-10 (rank : 85)	NC score	0.686341 (rank : 55)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

MYPT1_HUMAN
θ value	9.59137e-10 (rank : 86)	NC score	0.668229 (rank : 85)
Query Neighborhood Hits	368	Target Neighborhood Hits	723	Shared Neighborhood Hits	305
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

NOTC1_HUMAN
θ value	9.59137e-10 (rank : 87)	NC score	0.341859 (rank : 269)
Query Neighborhood Hits	368	Target Neighborhood Hits	906	Shared Neighborhood Hits	278
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	9.59137e-10 (rank : 88)	NC score	0.341847 (rank : 270)
Query Neighborhood Hits	368	Target Neighborhood Hits	1062	Shared Neighborhood Hits	281
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	9.59137e-10 (rank : 89)	NC score	0.343870 (rank : 268)
Query Neighborhood Hits	368	Target Neighborhood Hits	975	Shared Neighborhood Hits	283
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ASB15_HUMAN
θ value	1.25267e-09 (rank : 90)	NC score	0.670618 (rank : 80)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

RAI14_HUMAN
θ value	1.25267e-09 (rank : 91)	NC score	0.524124 (rank : 201)
Query Neighborhood Hits	368	Target Neighborhood Hits	1367	Shared Neighborhood Hits	324
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

ANR42_MOUSE
θ value	1.63604e-09 (rank : 92)	NC score	0.704300 (rank : 17)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ASB2_HUMAN
θ value	1.63604e-09 (rank : 93)	NC score	0.689715 (rank : 48)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	276
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASB2_MOUSE
θ value	1.63604e-09 (rank : 94)	NC score	0.686173 (rank : 57)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	273
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

FANK1_MOUSE
θ value	1.63604e-09 (rank : 95)	NC score	0.700519 (rank : 21)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	272
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANFY1_MOUSE
θ value	2.13673e-09 (rank : 96)	NC score	0.619887 (rank : 147)
Query Neighborhood Hits	368	Target Neighborhood Hits	480	Shared Neighborhood Hits	283
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BCL3_MOUSE
θ value	2.13673e-09 (rank : 97)	NC score	0.684955 (rank : 61)
Query Neighborhood Hits	368	Target Neighborhood Hits	388	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

MYPT1_MOUSE
θ value	2.13673e-09 (rank : 98)	NC score	0.683353 (rank : 63)
Query Neighborhood Hits	368	Target Neighborhood Hits	539	Shared Neighborhood Hits	290
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

ANKR1_MOUSE
θ value	2.79066e-09 (rank : 99)	NC score	0.695468 (rank : 33)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	276
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ASB16_MOUSE
θ value	2.79066e-09 (rank : 100)	NC score	0.677854 (rank : 70)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ASB9_HUMAN
θ value	2.79066e-09 (rank : 101)	NC score	0.667656 (rank : 87)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	251
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

MIB2_MOUSE
θ value	2.79066e-09 (rank : 102)	NC score	0.664413 (rank : 94)
Query Neighborhood Hits	368	Target Neighborhood Hits	409	Shared Neighborhood Hits	270
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ANR29_HUMAN
θ value	3.64472e-09 (rank : 103)	NC score	0.714855 (rank : 8)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	281
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

ANKR5_MOUSE
θ value	4.76016e-09 (rank : 104)	NC score	0.680814 (rank : 67)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	274
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

RN5A_HUMAN
θ value	4.76016e-09 (rank : 105)	NC score	0.655640 (rank : 112)
Query Neighborhood Hits	368	Target Neighborhood Hits	608	Shared Neighborhood Hits	276
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ANR35_HUMAN
θ value	6.21693e-09 (rank : 106)	NC score	0.637624 (rank : 133)
Query Neighborhood Hits	368	Target Neighborhood Hits	784	Shared Neighborhood Hits	299
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

RN5A_MOUSE
θ value	6.21693e-09 (rank : 107)	NC score	0.614107 (rank : 155)
Query Neighborhood Hits	368	Target Neighborhood Hits	899	Shared Neighborhood Hits	283
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB8_MOUSE
θ value	8.11959e-09 (rank : 108)	NC score	0.697720 (rank : 28)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANKR5_HUMAN
θ value	1.38499e-08 (rank : 109)	NC score	0.677599 (rank : 71)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	272
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_HUMAN
θ value	1.38499e-08 (rank : 110)	NC score	0.676149 (rank : 75)
Query Neighborhood Hits	368	Target Neighborhood Hits	355	Shared Neighborhood Hits	274
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

ANR10_MOUSE
θ value	1.38499e-08 (rank : 111)	NC score	0.670778 (rank : 79)
Query Neighborhood Hits	368	Target Neighborhood Hits	273	Shared Neighborhood Hits	260
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANR32_HUMAN
θ value	1.38499e-08 (rank : 112)	NC score	0.656675 (rank : 110)
Query Neighborhood Hits	368	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB5_HUMAN
θ value	1.38499e-08 (rank : 113)	NC score	0.663306 (rank : 96)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB8_HUMAN
θ value	1.38499e-08 (rank : 114)	NC score	0.696198 (rank : 30)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	274
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

AN36B_HUMAN
θ value	1.80886e-08 (rank : 115)	NC score	0.649410 (rank : 125)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	269
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

ANKS3_MOUSE
θ value	1.80886e-08 (rank : 116)	NC score	0.679954 (rank : 68)
Query Neighborhood Hits	368	Target Neighborhood Hits	355	Shared Neighborhood Hits	275
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

BCL3_HUMAN
θ value	1.80886e-08 (rank : 117)	NC score	0.688567 (rank : 50)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	273
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

CTTB2_HUMAN
θ value	1.80886e-08 (rank : 118)	NC score	0.607772 (rank : 161)
Query Neighborhood Hits	368	Target Neighborhood Hits	1061	Shared Neighborhood Hits	316
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

EHMT1_HUMAN
θ value	1.80886e-08 (rank : 119)	NC score	0.650906 (rank : 121)
Query Neighborhood Hits	368	Target Neighborhood Hits	417	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ASB10_MOUSE
θ value	2.36244e-08 (rank : 120)	NC score	0.691867 (rank : 42)
Query Neighborhood Hits	368	Target Neighborhood Hits	301	Shared Neighborhood Hits	275
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

FANK1_HUMAN
θ value	2.36244e-08 (rank : 121)	NC score	0.698710 (rank : 25)
Query Neighborhood Hits	368	Target Neighborhood Hits	326	Shared Neighborhood Hits	275
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

ZDH17_HUMAN
θ value	2.36244e-08 (rank : 122)	NC score	0.614543 (rank : 154)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	270
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

ANFY1_HUMAN
θ value	3.08544e-08 (rank : 123)	NC score	0.618217 (rank : 149)
Query Neighborhood Hits	368	Target Neighborhood Hits	480	Shared Neighborhood Hits	281
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

ANR10_HUMAN
θ value	3.08544e-08 (rank : 124)	NC score	0.669323 (rank : 83)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ACBD6_MOUSE
θ value	4.0297e-08 (rank : 125)	NC score	0.666915 (rank : 91)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKR2_MOUSE
θ value	5.26297e-08 (rank : 126)	NC score	0.695369 (rank : 34)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANR23_MOUSE
θ value	5.26297e-08 (rank : 127)	NC score	0.696759 (rank : 29)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	275
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

NFKB2_HUMAN
θ value	5.26297e-08 (rank : 128)	NC score	0.588939 (rank : 171)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	269
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ZDH17_MOUSE
θ value	5.26297e-08 (rank : 129)	NC score	0.610581 (rank : 157)
Query Neighborhood Hits	368	Target Neighborhood Hits	328	Shared Neighborhood Hits	267
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

ANR21_HUMAN
θ value	6.87365e-08 (rank : 130)	NC score	0.588706 (rank : 172)
Query Neighborhood Hits	368	Target Neighborhood Hits	864	Shared Neighborhood Hits	298
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

GABP3_MOUSE
θ value	6.87365e-08 (rank : 131)	NC score	0.686929 (rank : 53)
Query Neighborhood Hits	368	Target Neighborhood Hits	330	Shared Neighborhood Hits	272
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

ANKY2_HUMAN
θ value	1.17247e-07 (rank : 132)	NC score	0.626176 (rank : 139)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	259
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR32_MOUSE
θ value	1.17247e-07 (rank : 133)	NC score	0.650621 (rank : 122)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	256
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB15_MOUSE
θ value	1.17247e-07 (rank : 134)	NC score	0.659926 (rank : 106)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

ASB5_MOUSE
θ value	1.17247e-07 (rank : 135)	NC score	0.657939 (rank : 108)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	250
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

TRPA1_MOUSE
θ value	1.17247e-07 (rank : 136)	NC score	0.678241 (rank : 69)
Query Neighborhood Hits	368	Target Neighborhood Hits	343	Shared Neighborhood Hits	282
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ANKR2_HUMAN
θ value	1.53129e-07 (rank : 137)	NC score	0.694780 (rank : 35)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	282
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

NFKB2_MOUSE
θ value	1.53129e-07 (rank : 138)	NC score	0.577766 (rank : 176)
Query Neighborhood Hits	368	Target Neighborhood Hits	326	Shared Neighborhood Hits	265
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

NOTC2_HUMAN
θ value	1.53129e-07 (rank : 139)	NC score	0.337414 (rank : 271)
Query Neighborhood Hits	368	Target Neighborhood Hits	1113	Shared Neighborhood Hits	275
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ACBD6_HUMAN
θ value	1.99992e-07 (rank : 140)	NC score	0.663393 (rank : 95)
Query Neighborhood Hits	368	Target Neighborhood Hits	304	Shared Neighborhood Hits	274
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB13_MOUSE
θ value	1.99992e-07 (rank : 141)	NC score	0.686183 (rank : 56)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

GABP2_HUMAN
θ value	1.99992e-07 (rank : 142)	NC score	0.686533 (rank : 54)
Query Neighborhood Hits	368	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

GABP2_MOUSE
θ value	1.99992e-07 (rank : 143)	NC score	0.687881 (rank : 51)
Query Neighborhood Hits	368	Target Neighborhood Hits	429	Shared Neighborhood Hits	289
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

MTPN_MOUSE
θ value	1.99992e-07 (rank : 144)	NC score	0.692395 (rank : 40)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	262
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

POT15_HUMAN
θ value	1.99992e-07 (rank : 145)	NC score	0.589508 (rank : 170)
Query Neighborhood Hits	368	Target Neighborhood Hits	893	Shared Neighborhood Hits	298
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TRPA1_HUMAN
θ value	1.99992e-07 (rank : 146)	NC score	0.676334 (rank : 73)
Query Neighborhood Hits	368	Target Neighborhood Hits	339	Shared Neighborhood Hits	282
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

ASB13_HUMAN
θ value	2.61198e-07 (rank : 147)	NC score	0.685423 (rank : 60)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB14_MOUSE
θ value	2.61198e-07 (rank : 148)	NC score	0.659939 (rank : 105)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	266
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB1_MOUSE
θ value	2.61198e-07 (rank : 149)	NC score	0.655154 (rank : 113)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	265
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

MTPN_HUMAN
θ value	2.61198e-07 (rank : 150)	NC score	0.690219 (rank : 46)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	262
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

NOTC2_MOUSE
θ value	2.61198e-07 (rank : 151)	NC score	0.335567 (rank : 273)
Query Neighborhood Hits	368	Target Neighborhood Hits	1069	Shared Neighborhood Hits	277
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OSTF1_MOUSE
θ value	2.61198e-07 (rank : 152)	NC score	0.541319 (rank : 188)
Query Neighborhood Hits	368	Target Neighborhood Hits	467	Shared Neighborhood Hits	253
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANKY2_MOUSE
θ value	3.41135e-07 (rank : 153)	NC score	0.601087 (rank : 166)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	254
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

ANR39_MOUSE
θ value	3.41135e-07 (rank : 154)	NC score	0.697825 (rank : 27)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	272
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR49_HUMAN
θ value	3.41135e-07 (rank : 155)	NC score	0.693172 (rank : 37)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

SHAN1_HUMAN
θ value	3.41135e-07 (rank : 156)	NC score	0.571445 (rank : 178)
Query Neighborhood Hits	368	Target Neighborhood Hits	1041	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ANKR7_HUMAN
θ value	4.45536e-07 (rank : 157)	NC score	0.661146 (rank : 101)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	267
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

ANR39_HUMAN
θ value	4.45536e-07 (rank : 158)	NC score	0.699394 (rank : 23)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	273
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANR49_MOUSE
θ value	4.45536e-07 (rank : 159)	NC score	0.694618 (rank : 36)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR26_HUMAN
θ value	5.81887e-07 (rank : 160)	NC score	0.363974 (rank : 264)
Query Neighborhood Hits	368	Target Neighborhood Hits	1614	Shared Neighborhood Hits	322
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ASB10_HUMAN
θ value	5.81887e-07 (rank : 161)	NC score	0.691463 (rank : 43)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB11_MOUSE
θ value	5.81887e-07 (rank : 162)	NC score	0.660754 (rank : 103)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	251
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

OSTF1_HUMAN
θ value	7.59969e-07 (rank : 163)	NC score	0.527067 (rank : 198)
Query Neighborhood Hits	368	Target Neighborhood Hits	466	Shared Neighborhood Hits	252
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR26_MOUSE
θ value	9.92553e-07 (rank : 164)	NC score	0.380246 (rank : 257)
Query Neighborhood Hits	368	Target Neighborhood Hits	1554	Shared Neighborhood Hits	315
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC1_MOUSE
θ value	9.92553e-07 (rank : 165)	NC score	0.290722 (rank : 284)
Query Neighborhood Hits	368	Target Neighborhood Hits	916	Shared Neighborhood Hits	259
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

POTE8_HUMAN
θ value	9.92553e-07 (rank : 166)	NC score	0.622483 (rank : 144)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	277
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

CT086_HUMAN
θ value	1.69304e-06 (rank : 167)	NC score	0.672594 (rank : 78)
Query Neighborhood Hits	368	Target Neighborhood Hits	277	Shared Neighborhood Hits	263
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

IKBB_MOUSE
θ value	1.69304e-06 (rank : 168)	NC score	0.640292 (rank : 132)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	269
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR23_HUMAN
θ value	2.21117e-06 (rank : 169)	NC score	0.691039 (rank : 45)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	274
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

ANRA2_HUMAN
θ value	2.21117e-06 (rank : 170)	NC score	0.669086 (rank : 84)
Query Neighborhood Hits	368	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ANRA2_MOUSE
θ value	2.21117e-06 (rank : 171)	NC score	0.667309 (rank : 88)
Query Neighborhood Hits	368	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB1_HUMAN
θ value	2.21117e-06 (rank : 172)	NC score	0.654954 (rank : 115)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR47_MOUSE
θ value	2.88788e-06 (rank : 173)	NC score	0.590486 (rank : 169)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB9_MOUSE
θ value	2.88788e-06 (rank : 174)	NC score	0.652940 (rank : 118)
Query Neighborhood Hits	368	Target Neighborhood Hits	257	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

IKBE_MOUSE
θ value	2.88788e-06 (rank : 175)	NC score	0.656411 (rank : 111)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	266
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

CDN2D_HUMAN
θ value	3.77169e-06 (rank : 176)	NC score	0.659941 (rank : 104)
Query Neighborhood Hits	368	Target Neighborhood Hits	268	Shared Neighborhood Hits	258
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB12_HUMAN
θ value	4.92598e-06 (rank : 177)	NC score	0.649769 (rank : 123)
Query Neighborhood Hits	368	Target Neighborhood Hits	263	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ASB12_MOUSE
θ value	4.92598e-06 (rank : 178)	NC score	0.647707 (rank : 127)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	252
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANR22_HUMAN
θ value	6.43352e-06 (rank : 179)	NC score	0.661970 (rank : 98)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	236
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR40_HUMAN
θ value	6.43352e-06 (rank : 180)	NC score	0.530052 (rank : 197)
Query Neighborhood Hits	368	Target Neighborhood Hits	224	Shared Neighborhood Hits	199
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

KRIT1_MOUSE
θ value	6.43352e-06 (rank : 181)	NC score	0.577202 (rank : 177)
Query Neighborhood Hits	368	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

POT14_HUMAN
θ value	6.43352e-06 (rank : 182)	NC score	0.579913 (rank : 175)
Query Neighborhood Hits	368	Target Neighborhood Hits	403	Shared Neighborhood Hits	265
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

CLPB_HUMAN
θ value	1.09739e-05 (rank : 183)	NC score	0.506063 (rank : 208)
Query Neighborhood Hits	368	Target Neighborhood Hits	265	Shared Neighborhood Hits	233
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANKS6_MOUSE
θ value	1.43324e-05 (rank : 184)	NC score	0.668227 (rank : 86)
Query Neighborhood Hits	368	Target Neighborhood Hits	435	Shared Neighborhood Hits	278
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ANR40_MOUSE
θ value	1.43324e-05 (rank : 185)	NC score	0.526799 (rank : 200)
Query Neighborhood Hits	368	Target Neighborhood Hits	228	Shared Neighborhood Hits	203
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

IKBE_HUMAN
θ value	1.43324e-05 (rank : 186)	NC score	0.643166 (rank : 131)
Query Neighborhood Hits	368	Target Neighborhood Hits	288	Shared Neighborhood Hits	261
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

TEX14_HUMAN
θ value	1.43324e-05 (rank : 187)	NC score	0.328023 (rank : 277)
Query Neighborhood Hits	368	Target Neighborhood Hits	1103	Shared Neighborhood Hits	249
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR37_HUMAN
θ value	1.87187e-05 (rank : 188)	NC score	0.606660 (rank : 163)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	237
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ASB11_HUMAN
θ value	1.87187e-05 (rank : 189)	NC score	0.657254 (rank : 109)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	253
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ASB16_HUMAN
θ value	1.87187e-05 (rank : 190)	NC score	0.667082 (rank : 89)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	264
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

KRIT1_HUMAN
θ value	1.87187e-05 (rank : 191)	NC score	0.565954 (rank : 179)
Query Neighborhood Hits	368	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

RFXK_HUMAN
θ value	1.87187e-05 (rank : 192)	NC score	0.666994 (rank : 90)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	260
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ANKS6_HUMAN
θ value	2.44474e-05 (rank : 193)	NC score	0.666584 (rank : 92)
Query Neighborhood Hits	368	Target Neighborhood Hits	411	Shared Neighborhood Hits	279
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

ANR46_MOUSE
θ value	3.19293e-05 (rank : 194)	NC score	0.652611 (rank : 119)
Query Neighborhood Hits	368	Target Neighborhood Hits	274	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

A20A1_HUMAN
θ value	5.44631e-05 (rank : 195)	NC score	0.535523 (rank : 192)
Query Neighborhood Hits	368	Target Neighborhood Hits	698	Shared Neighborhood Hits	290
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A3_HUMAN
θ value	5.44631e-05 (rank : 196)	NC score	0.536173 (rank : 191)
Query Neighborhood Hits	368	Target Neighborhood Hits	692	Shared Neighborhood Hits	288
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A4_HUMAN
θ value	5.44631e-05 (rank : 197)	NC score	0.532601 (rank : 195)
Query Neighborhood Hits	368	Target Neighborhood Hits	710	Shared Neighborhood Hits	290
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR25_HUMAN
θ value	5.44631e-05 (rank : 198)	NC score	0.552697 (rank : 185)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	254
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

A20A2_HUMAN
θ value	7.1131e-05 (rank : 199)	NC score	0.534859 (rank : 193)
Query Neighborhood Hits	368	Target Neighborhood Hits	716	Shared Neighborhood Hits	295
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

ANR18_HUMAN
θ value	9.29e-05 (rank : 200)	NC score	0.498090 (rank : 212)
Query Neighborhood Hits	368	Target Neighborhood Hits	1106	Shared Neighborhood Hits	295
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

C43BP_HUMAN
θ value	9.29e-05 (rank : 201)	NC score	0.243942 (rank : 299)
Query Neighborhood Hits	368	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CDN2D_MOUSE
θ value	9.29e-05 (rank : 202)	NC score	0.652090 (rank : 120)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	254
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ANR46_HUMAN
θ value	0.000121331 (rank : 203)	NC score	0.654760 (rank : 116)
Query Neighborhood Hits	368	Target Neighborhood Hits	281	Shared Neighborhood Hits	261
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

ANR47_HUMAN
θ value	0.000121331 (rank : 204)	NC score	0.564744 (rank : 181)
Query Neighborhood Hits	368	Target Neighborhood Hits	369	Shared Neighborhood Hits	254
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB4_HUMAN
θ value	0.000121331 (rank : 205)	NC score	0.644493 (rank : 130)
Query Neighborhood Hits	368	Target Neighborhood Hits	264	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_MOUSE
θ value	0.000121331 (rank : 206)	NC score	0.644546 (rank : 129)
Query Neighborhood Hits	368	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

C43BP_MOUSE
θ value	0.000121331 (rank : 207)	NC score	0.240001 (rank : 302)
Query Neighborhood Hits	368	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

IKBB_HUMAN
θ value	0.000121331 (rank : 208)	NC score	0.628507 (rank : 137)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	266
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

AN36A_HUMAN
θ value	0.000158464 (rank : 209)	NC score	0.619402 (rank : 148)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANR37_MOUSE
θ value	0.000158464 (rank : 210)	NC score	0.587788 (rank : 173)
Query Neighborhood Hits	368	Target Neighborhood Hits	237	Shared Neighborhood Hits	229
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANS4B_HUMAN
θ value	0.000158464 (rank : 211)	NC score	0.615819 (rank : 151)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	255
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

TEX14_MOUSE
θ value	0.000158464 (rank : 212)	NC score	0.329023 (rank : 275)
Query Neighborhood Hits	368	Target Neighborhood Hits	1333	Shared Neighborhood Hits	280
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANR16_HUMAN
θ value	0.000270298 (rank : 213)	NC score	0.695952 (rank : 31)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	271
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANR25_MOUSE
θ value	0.000270298 (rank : 214)	NC score	0.540597 (rank : 189)
Query Neighborhood Hits	368	Target Neighborhood Hits	398	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

CDN2C_MOUSE
θ value	0.000270298 (rank : 215)	NC score	0.665330 (rank : 93)
Query Neighborhood Hits	368	Target Neighborhood Hits	270	Shared Neighborhood Hits	263
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ABTB2_MOUSE
θ value	0.00035302 (rank : 216)	NC score	0.471021 (rank : 221)
Query Neighborhood Hits	368	Target Neighborhood Hits	414	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

IKBA_MOUSE
θ value	0.00035302 (rank : 217)	NC score	0.647773 (rank : 126)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

RFXK_MOUSE
θ value	0.00035302 (rank : 218)	NC score	0.653684 (rank : 117)
Query Neighborhood Hits	368	Target Neighborhood Hits	273	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ANR15_HUMAN
θ value	0.000461057 (rank : 219)	NC score	0.587039 (rank : 174)
Query Neighborhood Hits	368	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

ANR19_HUMAN
θ value	0.000461057 (rank : 220)	NC score	0.615423 (rank : 153)
Query Neighborhood Hits	368	Target Neighborhood Hits	276	Shared Neighborhood Hits	261
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

HECD1_HUMAN
θ value	0.000461057 (rank : 221)	NC score	0.493646 (rank : 214)
Query Neighborhood Hits	368	Target Neighborhood Hits	371	Shared Neighborhood Hits	267
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

NUD12_HUMAN
θ value	0.000461057 (rank : 222)	NC score	0.459620 (rank : 224)
Query Neighborhood Hits	368	Target Neighborhood Hits	222	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ABTB2_HUMAN
θ value	0.000602161 (rank : 223)	NC score	0.479317 (rank : 219)
Query Neighborhood Hits	368	Target Neighborhood Hits	391	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

AN30A_HUMAN
θ value	0.000602161 (rank : 224)	NC score	0.466262 (rank : 222)
Query Neighborhood Hits	368	Target Neighborhood Hits	1119	Shared Neighborhood Hits	297
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

POT22_HUMAN
θ value	0.000602161 (rank : 225)	NC score	0.543822 (rank : 186)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	251
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

AN13B_HUMAN
θ value	0.000786445 (rank : 226)	NC score	0.442305 (rank : 231)
Query Neighborhood Hits	368	Target Neighborhood Hits	265	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_MOUSE
θ value	0.000786445 (rank : 227)	NC score	0.442563 (rank : 230)
Query Neighborhood Hits	368	Target Neighborhood Hits	276	Shared Neighborhood Hits	250
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

CDN2C_HUMAN
θ value	0.000786445 (rank : 228)	NC score	0.662040 (rank : 97)
Query Neighborhood Hits	368	Target Neighborhood Hits	262	Shared Neighborhood Hits	257
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR43_MOUSE
θ value	0.00102713 (rank : 229)	NC score	0.507500 (rank : 207)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANS4B_MOUSE
θ value	0.00102713 (rank : 230)	NC score	0.603193 (rank : 165)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

CLPB_MOUSE
θ value	0.00102713 (rank : 231)	NC score	0.565735 (rank : 180)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	248
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

IKBA_HUMAN
θ value	0.00102713 (rank : 232)	NC score	0.655111 (rank : 114)
Query Neighborhood Hits	368	Target Neighborhood Hits	280	Shared Neighborhood Hits	265
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

NUD12_MOUSE
θ value	0.00102713 (rank : 233)	NC score	0.486403 (rank : 216)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	220
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ANR43_HUMAN
θ value	0.00134147 (rank : 234)	NC score	0.511277 (rank : 206)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

UACA_HUMAN
θ value	0.00134147 (rank : 235)	NC score	0.401255 (rank : 250)
Query Neighborhood Hits	368	Target Neighborhood Hits	1622	Shared Neighborhood Hits	321
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

ASPP1_HUMAN
θ value	0.00175202 (rank : 236)	NC score	0.449781 (rank : 227)
Query Neighborhood Hits	368	Target Neighborhood Hits	956	Shared Neighborhood Hits	289
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ASPP1_MOUSE
θ value	0.00175202 (rank : 237)	NC score	0.434464 (rank : 236)
Query Neighborhood Hits	368	Target Neighborhood Hits	1244	Shared Neighborhood Hits	292
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

TRPV3_MOUSE
θ value	0.00175202 (rank : 238)	NC score	0.195421 (rank : 309)
Query Neighborhood Hits	368	Target Neighborhood Hits	188	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

DGKZ_HUMAN
θ value	0.00298849 (rank : 239)	NC score	0.316564 (rank : 279)
Query Neighborhood Hits	368	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

SWP70_HUMAN
θ value	0.00298849 (rank : 240)	NC score	0.078989 (rank : 323)
Query Neighborhood Hits	368	Target Neighborhood Hits	973	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

AN13C_HUMAN
θ value	0.00390308 (rank : 241)	NC score	0.437992 (rank : 235)
Query Neighborhood Hits	368	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

AN13C_MOUSE
θ value	0.00390308 (rank : 242)	NC score	0.429599 (rank : 240)
Query Neighborhood Hits	368	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

MPP8_HUMAN
θ value	0.00390308 (rank : 243)	NC score	0.533675 (rank : 194)
Query Neighborhood Hits	368	Target Neighborhood Hits	948	Shared Neighborhood Hits	272
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

UACA_MOUSE
θ value	0.00390308 (rank : 244)	NC score	0.382253 (rank : 255)
Query Neighborhood Hits	368	Target Neighborhood Hits	1620	Shared Neighborhood Hits	319
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

AN13A_MOUSE
θ value	0.00509761 (rank : 245)	NC score	0.371779 (rank : 262)
Query Neighborhood Hits	368	Target Neighborhood Hits	226	Shared Neighborhood Hits	209
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

PKHA3_MOUSE
θ value	0.00509761 (rank : 246)	NC score	0.265955 (rank : 289)
Query Neighborhood Hits	368	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

AN13A_HUMAN
θ value	0.00665767 (rank : 247)	NC score	0.389548 (rank : 253)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	215
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

CENB5_HUMAN
θ value	0.00665767 (rank : 248)	NC score	0.438143 (rank : 234)
Query Neighborhood Hits	368	Target Neighborhood Hits	395	Shared Neighborhood Hits	264
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

TRPV3_HUMAN
θ value	0.00665767 (rank : 249)	NC score	0.191682 (rank : 310)
Query Neighborhood Hits	368	Target Neighborhood Hits	198	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

USH1G_HUMAN
θ value	0.00665767 (rank : 250)	NC score	0.609028 (rank : 159)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

USH1G_MOUSE
θ value	0.00665767 (rank : 251)	NC score	0.609094 (rank : 158)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	254
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

ANR41_HUMAN
θ value	0.00869519 (rank : 252)	NC score	0.605605 (rank : 164)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	246
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ASPP2_HUMAN
θ value	0.00869519 (rank : 253)	NC score	0.459343 (rank : 225)
Query Neighborhood Hits	368	Target Neighborhood Hits	1156	Shared Neighborhood Hits	301
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

DDFL1_MOUSE
θ value	0.00869519 (rank : 254)	NC score	0.378350 (rank : 259)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	251
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

GIT2_MOUSE
θ value	0.00869519 (rank : 255)	NC score	0.405070 (rank : 248)
Query Neighborhood Hits	368	Target Neighborhood Hits	323	Shared Neighborhood Hits	248
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

SWP70_MOUSE
θ value	0.0113563 (rank : 256)	NC score	0.076381 (rank : 324)
Query Neighborhood Hits	368	Target Neighborhood Hits	1097	Shared Neighborhood Hits	82
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

DGKZ_MOUSE
θ value	0.0148317 (rank : 257)	NC score	0.297604 (rank : 283)
Query Neighborhood Hits	368	Target Neighborhood Hits	542	Shared Neighborhood Hits	200
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

ANR38_HUMAN
θ value	0.0193708 (rank : 258)	NC score	0.526945 (rank : 199)
Query Neighborhood Hits	368	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

DGKI_HUMAN
θ value	0.0330416 (rank : 259)	NC score	0.283017 (rank : 286)
Query Neighborhood Hits	368	Target Neighborhood Hits	609	Shared Neighborhood Hits	213
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

GLSL_HUMAN
θ value	0.0330416 (rank : 260)	NC score	0.418077 (rank : 246)
Query Neighborhood Hits	368	Target Neighborhood Hits	211	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

RSNL2_HUMAN
θ value	0.0330416 (rank : 261)	NC score	0.218420 (rank : 306)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

GIT1_HUMAN
θ value	0.0431538 (rank : 262)	NC score	0.394491 (rank : 251)
Query Neighborhood Hits	368	Target Neighborhood Hits	336	Shared Neighborhood Hits	251
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
θ value	0.0431538 (rank : 263)	NC score	0.393554 (rank : 252)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	251
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

GLSL_MOUSE
θ value	0.0431538 (rank : 264)	NC score	0.407224 (rank : 247)
Query Neighborhood Hits	368	Target Neighborhood Hits	212	Shared Neighborhood Hits	198
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

TRPV5_HUMAN
θ value	0.0431538 (rank : 265)	NC score	0.367255 (rank : 263)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	219
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

DDEF1_MOUSE
θ value	0.0563607 (rank : 266)	NC score	0.272842 (rank : 287)
Query Neighborhood Hits	368	Target Neighborhood Hits	592	Shared Neighborhood Hits	202
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

GIT2_HUMAN
θ value	0.0563607 (rank : 267)	NC score	0.373075 (rank : 261)
Query Neighborhood Hits	368	Target Neighborhood Hits	381	Shared Neighborhood Hits	252
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

ANR38_MOUSE
θ value	0.0736092 (rank : 268)	NC score	0.505424 (rank : 209)
Query Neighborhood Hits	368	Target Neighborhood Hits	512	Shared Neighborhood Hits	249
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

IASPP_HUMAN
θ value	0.0736092 (rank : 269)	NC score	0.447497 (rank : 228)
Query Neighborhood Hits	368	Target Neighborhood Hits	688	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TRPV6_MOUSE
θ value	0.0736092 (rank : 270)	NC score	0.432264 (rank : 238)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	245
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

DDFL1_HUMAN
θ value	0.0961366 (rank : 271)	NC score	0.299705 (rank : 282)
Query Neighborhood Hits	368	Target Neighborhood Hits	353	Shared Neighborhood Hits	231
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

PKHA3_HUMAN
θ value	0.0961366 (rank : 272)	NC score	0.251980 (rank : 298)
Query Neighborhood Hits	368	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

BAT4_MOUSE
θ value	0.125558 (rank : 273)	NC score	0.241769 (rank : 301)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

CENB1_HUMAN
θ value	0.125558 (rank : 274)	NC score	0.433461 (rank : 237)
Query Neighborhood Hits	368	Target Neighborhood Hits	383	Shared Neighborhood Hits	258
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

MYH13_HUMAN
θ value	0.125558 (rank : 275)	NC score	0.021625 (rank : 361)
Query Neighborhood Hits	368	Target Neighborhood Hits	1504	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

ANR33_MOUSE
θ value	0.163984 (rank : 276)	NC score	0.540301 (rank : 190)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

CLR59_HUMAN
θ value	0.163984 (rank : 277)	NC score	0.255416 (rank : 295)
Query Neighborhood Hits	368	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

TRPV5_MOUSE
θ value	0.163984 (rank : 278)	NC score	0.388929 (rank : 254)
Query Neighborhood Hits	368	Target Neighborhood Hits	278	Shared Neighborhood Hits	238
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ASB14_HUMAN
θ value	0.21417 (rank : 279)	NC score	0.428821 (rank : 241)
Query Neighborhood Hits	368	Target Neighborhood Hits	187	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

BAT4_HUMAN
θ value	0.279714 (rank : 280)	NC score	0.218315 (rank : 307)
Query Neighborhood Hits	368	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

DDEF2_HUMAN
θ value	0.279714 (rank : 281)	NC score	0.330616 (rank : 274)
Query Neighborhood Hits	368	Target Neighborhood Hits	599	Shared Neighborhood Hits	246
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	0.279714 (rank : 282)	NC score	0.328191 (rank : 276)
Query Neighborhood Hits	368	Target Neighborhood Hits	625	Shared Neighborhood Hits	249
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

EP15R_HUMAN
θ value	0.279714 (rank : 283)	NC score	0.032601 (rank : 345)
Query Neighborhood Hits	368	Target Neighborhood Hits	1083	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

BPAEA_MOUSE
θ value	0.365318 (rank : 284)	NC score	0.031677 (rank : 347)
Query Neighborhood Hits	368	Target Neighborhood Hits	1480	Shared Neighborhood Hits	73
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CENB2_HUMAN
θ value	0.365318 (rank : 285)	NC score	0.418129 (rank : 245)
Query Neighborhood Hits	368	Target Neighborhood Hits	425	Shared Neighborhood Hits	259
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

EP15R_MOUSE
θ value	0.365318 (rank : 286)	NC score	0.034267 (rank : 341)
Query Neighborhood Hits	368	Target Neighborhood Hits	1135	Shared Neighborhood Hits	72
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

IASPP_MOUSE
θ value	0.365318 (rank : 287)	NC score	0.401845 (rank : 249)
Query Neighborhood Hits	368	Target Neighborhood Hits	1024	Shared Neighborhood Hits	260
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RSNL2_MOUSE
θ value	0.365318 (rank : 288)	NC score	0.188298 (rank : 311)
Query Neighborhood Hits	368	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV6_HUMAN
θ value	0.365318 (rank : 289)	NC score	0.362006 (rank : 265)
Query Neighborhood Hits	368	Target Neighborhood Hits	262	Shared Neighborhood Hits	219
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

CDN2B_HUMAN
θ value	0.47712 (rank : 290)	NC score	0.483951 (rank : 217)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	190
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

CENG2_HUMAN
θ value	0.47712 (rank : 291)	NC score	0.265914 (rank : 290)
Query Neighborhood Hits	368	Target Neighborhood Hits	471	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG2_MOUSE
θ value	0.47712 (rank : 292)	NC score	0.264565 (rank : 292)
Query Neighborhood Hits	368	Target Neighborhood Hits	463	Shared Neighborhood Hits	244
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

DIAP1_MOUSE
θ value	0.47712 (rank : 293)	NC score	0.027971 (rank : 352)
Query Neighborhood Hits	368	Target Neighborhood Hits	839	Shared Neighborhood Hits	56
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

ANKZ1_HUMAN
θ value	0.62314 (rank : 294)	NC score	0.270307 (rank : 288)
Query Neighborhood Hits	368	Target Neighborhood Hits	236	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

ANR33_HUMAN
θ value	0.62314 (rank : 295)	NC score	0.531032 (rank : 196)
Query Neighborhood Hits	368	Target Neighborhood Hits	215	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

MRCKA_HUMAN
θ value	0.62314 (rank : 296)	NC score	0.014941 (rank : 370)
Query Neighborhood Hits	368	Target Neighborhood Hits	1999	Shared Neighborhood Hits	79
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

ABTB1_MOUSE
θ value	0.813845 (rank : 297)	NC score	0.253742 (rank : 297)
Query Neighborhood Hits	368	Target Neighborhood Hits	349	Shared Neighborhood Hits	177
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

DIAP1_HUMAN
θ value	0.813845 (rank : 298)	NC score	0.024534 (rank : 357)
Query Neighborhood Hits	368	Target Neighborhood Hits	784	Shared Neighborhood Hits	48
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

PRP4_HUMAN
θ value	0.813845 (rank : 299)	NC score	0.003164 (rank : 395)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

PRP4_MOUSE
θ value	0.813845 (rank : 300)	NC score	0.003229 (rank : 394)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

TRIPB_HUMAN
θ value	0.813845 (rank : 301)	NC score	0.037282 (rank : 337)
Query Neighborhood Hits	368	Target Neighborhood Hits	1587	Shared Neighborhood Hits	86
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ANKZ1_MOUSE
θ value	1.06291 (rank : 302)	NC score	0.283795 (rank : 285)
Query Neighborhood Hits	368	Target Neighborhood Hits	208	Shared Neighborhood Hits	148
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

HSF2_HUMAN
θ value	1.06291 (rank : 303)	NC score	0.017228 (rank : 368)
Query Neighborhood Hits	368	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

RAE2_MOUSE
θ value	1.06291 (rank : 304)	NC score	0.010124 (rank : 383)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

REST_MOUSE
θ value	1.06291 (rank : 305)	NC score	0.034423 (rank : 340)
Query Neighborhood Hits	368	Target Neighborhood Hits	1506	Shared Neighborhood Hits	84
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SYNE1_HUMAN
θ value	1.06291 (rank : 306)	NC score	0.023473 (rank : 358)
Query Neighborhood Hits	368	Target Neighborhood Hits	1484	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ANKR9_HUMAN
θ value	1.38821 (rank : 307)	NC score	0.200427 (rank : 308)
Query Neighborhood Hits	368	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKR9_MOUSE
θ value	1.38821 (rank : 308)	NC score	0.241833 (rank : 300)
Query Neighborhood Hits	368	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

ANKY1_HUMAN
θ value	1.38821 (rank : 309)	NC score	0.427921 (rank : 242)
Query Neighborhood Hits	368	Target Neighborhood Hits	248	Shared Neighborhood Hits	202
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

SNCAP_HUMAN
θ value	1.38821 (rank : 310)	NC score	0.558353 (rank : 183)
Query Neighborhood Hits	368	Target Neighborhood Hits	313	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

TS101_HUMAN
θ value	1.38821 (rank : 311)	NC score	0.028327 (rank : 351)
Query Neighborhood Hits	368	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

TS101_MOUSE
θ value	1.38821 (rank : 312)	NC score	0.027617 (rank : 353)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

ABTB1_HUMAN
θ value	1.81305 (rank : 313)	NC score	0.222069 (rank : 305)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	161
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

CD2A1_MOUSE
θ value	1.81305 (rank : 314)	NC score	0.543585 (rank : 187)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	198
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

CENG1_MOUSE
θ value	1.81305 (rank : 315)	NC score	0.265606 (rank : 291)
Query Neighborhood Hits	368	Target Neighborhood Hits	531	Shared Neighborhood Hits	231
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

GLSK_HUMAN
θ value	1.81305 (rank : 316)	NC score	0.380558 (rank : 256)
Query Neighborhood Hits	368	Target Neighborhood Hits	204	Shared Neighborhood Hits	186
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

GOGA5_MOUSE
θ value	1.81305 (rank : 317)	NC score	0.030780 (rank : 349)
Query Neighborhood Hits	368	Target Neighborhood Hits	1434	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

LIGA_HUMAN
θ value	1.81305 (rank : 318)	NC score	0.013332 (rank : 373)
Query Neighborhood Hits	368	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

MACF1_HUMAN
θ value	1.81305 (rank : 319)	NC score	0.021698 (rank : 359)
Query Neighborhood Hits	368	Target Neighborhood Hits	1341	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	1.81305 (rank : 320)	NC score	0.025060 (rank : 356)
Query Neighborhood Hits	368	Target Neighborhood Hits	1321	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

M4K4_HUMAN
θ value	2.36792 (rank : 321)	NC score	0.008285 (rank : 386)
Query Neighborhood Hits	368	Target Neighborhood Hits	1589	Shared Neighborhood Hits	68
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_MOUSE
θ value	2.36792 (rank : 322)	NC score	0.008097 (rank : 388)
Query Neighborhood Hits	368	Target Neighborhood Hits	1560	Shared Neighborhood Hits	63
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PRGC2_MOUSE
θ value	2.36792 (rank : 323)	NC score	0.012364 (rank : 376)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

RL21_HUMAN
θ value	2.36792 (rank : 324)	NC score	0.013806 (rank : 372)
Query Neighborhood Hits	368	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P46778, Q16699	Gene names	RPL21
Domain Architecture
Description	60S ribosomal protein L21.

CENG1_HUMAN
θ value	3.0926 (rank : 325)	NC score	0.264131 (rank : 293)
Query Neighborhood Hits	368	Target Neighborhood Hits	544	Shared Neighborhood Hits	234
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

CENPF_HUMAN
θ value	3.0926 (rank : 326)	NC score	0.029985 (rank : 350)
Query Neighborhood Hits	368	Target Neighborhood Hits	1932	Shared Neighborhood Hits	87
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

DESP_HUMAN
θ value	3.0926 (rank : 327)	NC score	0.033050 (rank : 343)
Query Neighborhood Hits	368	Target Neighborhood Hits	1470	Shared Neighborhood Hits	77
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

MYH8_HUMAN
θ value	3.0926 (rank : 328)	NC score	0.021192 (rank : 363)
Query Neighborhood Hits	368	Target Neighborhood Hits	1610	Shared Neighborhood Hits	82
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

CDN2B_MOUSE
θ value	4.03905 (rank : 329)	NC score	0.515205 (rank : 204)
Query Neighborhood Hits	368	Target Neighborhood Hits	201	Shared Neighborhood Hits	194
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

CELR1_HUMAN
θ value	4.03905 (rank : 330)	NC score	0.007834 (rank : 389)
Query Neighborhood Hits	368	Target Neighborhood Hits	613	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CEP68_HUMAN
θ value	4.03905 (rank : 331)	NC score	0.010981 (rank : 380)
Query Neighborhood Hits	368	Target Neighborhood Hits	128	Shared Neighborhood Hits	10
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

DPOLZ_HUMAN
θ value	4.03905 (rank : 332)	NC score	0.006968 (rank : 390)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

HMMR_MOUSE
θ value	4.03905 (rank : 333)	NC score	0.032276 (rank : 346)
Query Neighborhood Hits	368	Target Neighborhood Hits	1178	Shared Neighborhood Hits	69
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

PACN3_HUMAN
θ value	4.03905 (rank : 334)	NC score	0.011305 (rank : 379)
Query Neighborhood Hits	368	Target Neighborhood Hits	385	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

SPTA2_HUMAN
θ value	4.03905 (rank : 335)	NC score	0.019487 (rank : 366)
Query Neighborhood Hits	368	Target Neighborhood Hits	888	Shared Neighborhood Hits	60
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

T3JAM_HUMAN
θ value	4.03905 (rank : 336)	NC score	0.026678 (rank : 354)
Query Neighborhood Hits	368	Target Neighborhood Hits	533	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TRPC6_HUMAN
θ value	4.03905 (rank : 337)	NC score	0.082396 (rank : 321)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

ARHG7_MOUSE
θ value	5.27518 (rank : 338)	NC score	0.013985 (rank : 371)
Query Neighborhood Hits	368	Target Neighborhood Hits	396	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CENPE_HUMAN
θ value	5.27518 (rank : 339)	NC score	0.026364 (rank : 355)
Query Neighborhood Hits	368	Target Neighborhood Hits	2060	Shared Neighborhood Hits	90
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

EEA1_MOUSE
θ value	5.27518 (rank : 340)	NC score	0.031199 (rank : 348)
Query Neighborhood Hits	368	Target Neighborhood Hits	1637	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FYB_HUMAN
θ value	5.27518 (rank : 341)	NC score	0.016220 (rank : 369)
Query Neighborhood Hits	368	Target Neighborhood Hits	379	Shared Neighborhood Hits	15
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

REST_HUMAN
θ value	5.27518 (rank : 342)	NC score	0.035393 (rank : 338)
Query Neighborhood Hits	368	Target Neighborhood Hits	1605	Shared Neighborhood Hits	80
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

ROCK1_MOUSE
θ value	5.27518 (rank : 343)	NC score	0.018635 (rank : 367)
Query Neighborhood Hits	368	Target Neighborhood Hits	2126	Shared Neighborhood Hits	85
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ASB6_MOUSE
θ value	6.88961 (rank : 344)	NC score	0.559420 (rank : 182)
Query Neighborhood Hits	368	Target Neighborhood Hits	264	Shared Neighborhood Hits	240
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ELOA2_HUMAN
θ value	6.88961 (rank : 345)	NC score	0.004363 (rank : 391)
Query Neighborhood Hits	368	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

FYB_MOUSE
θ value	6.88961 (rank : 346)	NC score	0.010720 (rank : 381)
Query Neighborhood Hits	368	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

GOGB1_HUMAN
θ value	6.88961 (rank : 347)	NC score	0.035228 (rank : 339)
Query Neighborhood Hits	368	Target Neighborhood Hits	2297	Shared Neighborhood Hits	95
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

IFIH1_MOUSE
θ value	6.88961 (rank : 348)	NC score	0.001395 (rank : 396)
Query Neighborhood Hits	368	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

KI21A_MOUSE
θ value	6.88961 (rank : 349)	NC score	0.013298 (rank : 374)
Query Neighborhood Hits	368	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LRP1B_HUMAN
θ value	6.88961 (rank : 350)	NC score	0.020769 (rank : 364)
Query Neighborhood Hits	368	Target Neighborhood Hits	602	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MINK1_HUMAN
θ value	6.88961 (rank : 351)	NC score	0.003461 (rank : 393)
Query Neighborhood Hits	368	Target Neighborhood Hits	1477	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_MOUSE
θ value	6.88961 (rank : 352)	NC score	0.003874 (rank : 392)
Query Neighborhood Hits	368	Target Neighborhood Hits	1451	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MYH6_HUMAN
θ value	6.88961 (rank : 353)	NC score	0.021620 (rank : 362)
Query Neighborhood Hits	368	Target Neighborhood Hits	1426	Shared Neighborhood Hits	80
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	6.88961 (rank : 354)	NC score	0.021666 (rank : 360)
Query Neighborhood Hits	368	Target Neighborhood Hits	1501	Shared Neighborhood Hits	80
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

PACN2_MOUSE
θ value	6.88961 (rank : 355)	NC score	0.012063 (rank : 378)
Query Neighborhood Hits	368	Target Neighborhood Hits	382	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

SPTB1_HUMAN
θ value	6.88961 (rank : 356)	NC score	0.010190 (rank : 382)
Query Neighborhood Hits	368	Target Neighborhood Hits	541	Shared Neighborhood Hits	48
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

TRPC3_HUMAN
θ value	6.88961 (rank : 357)	NC score	0.063893 (rank : 326)
Query Neighborhood Hits	368	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC3_MOUSE
θ value	6.88961 (rank : 358)	NC score	0.058024 (rank : 328)
Query Neighborhood Hits	368	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

ABCC9_MOUSE
θ value	8.99809 (rank : 359)	NC score	-0.002195 (rank : 397)
Query Neighborhood Hits	368	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).

CT012_MOUSE
θ value	8.99809 (rank : 360)	NC score	0.335583 (rank : 272)
Query Neighborhood Hits	368	Target Neighborhood Hits	229	Shared Neighborhood Hits	174
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

DFFA_HUMAN
θ value	8.99809 (rank : 361)	NC score	0.009618 (rank : 384)
Query Neighborhood Hits	368	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	O00273, Q96I97, Q9Y6C6	Gene names	DFFA, DFF1, DFF45
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

KLC1_MOUSE
θ value	8.99809 (rank : 362)	NC score	0.008975 (rank : 385)
Query Neighborhood Hits	368	Target Neighborhood Hits	357	Shared Neighborhood Hits	38
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

LRP1B_MOUSE
θ value	8.99809 (rank : 363)	NC score	0.019937 (rank : 365)
Query Neighborhood Hits	368	Target Neighborhood Hits	606	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

MORC1_HUMAN
θ value	8.99809 (rank : 364)	NC score	0.008119 (rank : 387)
Query Neighborhood Hits	368	Target Neighborhood Hits	127	Shared Neighborhood Hits	19
SwissProt Accessions	Q86VD1, Q7L8E2, Q9NSG7, Q9Y6D4	Gene names	MORC1, MORC
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 1.

OCLN_HUMAN
θ value	8.99809 (rank : 365)	NC score	0.012876 (rank : 375)
Query Neighborhood Hits	368	Target Neighborhood Hits	131	Shared Neighborhood Hits	19
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

PACN2_HUMAN
θ value	8.99809 (rank : 366)	NC score	0.012085 (rank : 377)
Query Neighborhood Hits	368	Target Neighborhood Hits	339	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PININ_MOUSE
θ value	8.99809 (rank : 367)	NC score	0.033371 (rank : 342)
Query Neighborhood Hits	368	Target Neighborhood Hits	777	Shared Neighborhood Hits	57
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SYCP1_MOUSE
θ value	8.99809 (rank : 368)	NC score	0.033029 (rank : 344)
Query Neighborhood Hits	368	Target Neighborhood Hits	1456	Shared Neighborhood Hits	82
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ANKF1_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.103223 (rank : 318)
Query Neighborhood Hits	368	Target Neighborhood Hits	126	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

ANR45_HUMAN
θ value	θ > 10 (rank : 370)	NC score	0.431809 (rank : 239)
Query Neighborhood Hits	368	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ANR45_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.460625 (rank : 223)
Query Neighborhood Hits	368	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

ASB6_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.555919 (rank : 184)
Query Neighborhood Hits	368	Target Neighborhood Hits	256	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

CD2A1_HUMAN
θ value	θ > 10 (rank : 373)	NC score	0.477043 (rank : 220)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	189
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

CENG3_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.237131 (rank : 303)
Query Neighborhood Hits	368	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.236829 (rank : 304)
Query Neighborhood Hits	368	Target Neighborhood Hits	467	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CMTA1_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.138722 (rank : 315)
Query Neighborhood Hits	368	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

CMTA2_HUMAN
θ value	θ > 10 (rank : 377)	NC score	0.109780 (rank : 317)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	85
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CMTA2_MOUSE
θ value	θ > 10 (rank : 378)	NC score	0.099642 (rank : 319)
Query Neighborhood Hits	368	Target Neighborhood Hits	216	Shared Neighborhood Hits	73
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

CT012_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.308957 (rank : 281)
Query Neighborhood Hits	368	Target Neighborhood Hits	205	Shared Neighborhood Hits	162
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

CU081_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.071635 (rank : 325)
Query Neighborhood Hits	368	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

IKBL_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.260150 (rank : 294)
Query Neighborhood Hits	368	Target Neighborhood Hits	168	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

IKBL_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.253864 (rank : 296)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	138
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

LRRK1_MOUSE
θ value	θ > 10 (rank : 383)	NC score	0.062519 (rank : 327)
Query Neighborhood Hits	368	Target Neighborhood Hits	1267	Shared Neighborhood Hits	126
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

RELB_HUMAN
θ value	θ > 10 (rank : 384)	NC score	0.050640 (rank : 335)
Query Neighborhood Hits	368	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

RELB_MOUSE
θ value	θ > 10 (rank : 385)	NC score	0.050675 (rank : 334)
Query Neighborhood Hits	368	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

REL_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.051631 (rank : 331)
Query Neighborhood Hits	368	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_MOUSE
θ value	θ > 10 (rank : 387)	NC score	0.052000 (rank : 330)
Query Neighborhood Hits	368	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

TF65_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.050217 (rank : 336)
Query Neighborhood Hits	368	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TRPC6_MOUSE
θ value	θ > 10 (rank : 389)	NC score	0.057261 (rank : 329)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	86
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC7_HUMAN
θ value	θ > 10 (rank : 390)	NC score	0.050778 (rank : 333)
Query Neighborhood Hits	368	Target Neighborhood Hits	123	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	θ > 10 (rank : 391)	NC score	0.050787 (rank : 332)
Query Neighborhood Hits	368	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPV1_HUMAN
θ value	θ > 10 (rank : 392)	NC score	0.165330 (rank : 313)
Query Neighborhood Hits	368	Target Neighborhood Hits	184	Shared Neighborhood Hits	138
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	θ > 10 (rank : 393)	NC score	0.176469 (rank : 312)
Query Neighborhood Hits	368	Target Neighborhood Hits	189	Shared Neighborhood Hits	146
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV2_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.152590 (rank : 314)
Query Neighborhood Hits	368	Target Neighborhood Hits	130	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.116035 (rank : 316)
Query Neighborhood Hits	368	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

TRPV4_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.086825 (rank : 320)
Query Neighborhood Hits	368	Target Neighborhood Hits	150	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV4_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.079047 (rank : 322)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

Hits sorted by NC score

OSBL1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	368	Target Neighborhood Hits	368	Shared Neighborhood Hits	368
SwissProt Accessions	Q9BXW6, Q9BZF5, Q9NW87	Gene names	OSBPL1A, ORP1, OSBP8, OSBPL1
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

OSBL1_MOUSE
NC score	0.995068 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	368	Target Neighborhood Hits	336	Shared Neighborhood Hits	310
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

PSD10_HUMAN
NC score	0.733429 (rank : 3)	θ value	3.40345e-15 (rank : 34)
Query Neighborhood Hits	368	Target Neighborhood Hits	301	Shared Neighborhood Hits	280
SwissProt Accessions	O75832	Gene names	PSMD10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

PSD10_MOUSE
NC score	0.732360 (rank : 4)	θ value	6.41864e-14 (rank : 41)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	278
SwissProt Accessions	Q9Z2X2, Q9D7N8	Gene names	Psmd10
Domain Architecture
Description	26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28) (Gankyrin).

ASB7_HUMAN
NC score	0.718770 (rank : 5)	θ value	1.80466e-16 (rank : 25)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	277
SwissProt Accessions	Q9H672, Q7Z4S3	Gene names	ASB7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ASB7_MOUSE
NC score	0.718708 (rank : 6)	θ value	1.80466e-16 (rank : 26)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	277
SwissProt Accessions	Q91ZU0	Gene names	Asb7
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 7 (ASB-7).

ANKR6_HUMAN
NC score	0.715467 (rank : 7)	θ value	9.90251e-15 (rank : 37)
Query Neighborhood Hits	368	Target Neighborhood Hits	439	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR29_HUMAN
NC score	0.714855 (rank : 8)	θ value	3.64472e-09 (rank : 103)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	281
SwissProt Accessions	Q8N6D5, Q6ZWE8, Q96LU9	Gene names	ANKRD29
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 29.

TNKS2_HUMAN
NC score	0.714685 (rank : 9)	θ value	1.2077e-20 (rank : 20)
Query Neighborhood Hits	368	Target Neighborhood Hits	361	Shared Neighborhood Hits	285
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

TNKS1_HUMAN
NC score	0.710683 (rank : 10)	θ value	5.99374e-20 (rank : 21)
Query Neighborhood Hits	368	Target Neighborhood Hits	477	Shared Neighborhood Hits	284
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

ASB3_HUMAN
NC score	0.710206 (rank : 11)	θ value	7.58209e-15 (rank : 36)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	279
SwissProt Accessions	Q9Y575, Q9NVZ2	Gene names	ASB3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR50_HUMAN
NC score	0.709882 (rank : 12)	θ value	8.38298e-14 (rank : 42)
Query Neighborhood Hits	368	Target Neighborhood Hits	361	Shared Neighborhood Hits	283
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

ASB3_MOUSE
NC score	0.708562 (rank : 13)	θ value	1.42992e-13 (rank : 43)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WV72	Gene names	Asb3
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 3 (ASB-3).

ANR44_HUMAN
NC score	0.707797 (rank : 14)	θ value	5.25075e-16 (rank : 29)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	282
SwissProt Accessions	Q8N8A2, Q6P480, Q86VL5, Q8IZ72, Q9UFA4	Gene names	ANKRD44
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 44.

ANR42_HUMAN
NC score	0.706565 (rank : 15)	θ value	1.33837e-11 (rank : 62)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	271
SwissProt Accessions	Q8N9B4, Q49A49	Gene names	ANKRD42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR28_MOUSE
NC score	0.705619 (rank : 16)	θ value	5.8054e-15 (rank : 35)
Query Neighborhood Hits	368	Target Neighborhood Hits	314	Shared Neighborhood Hits	284
SwissProt Accessions	Q505D1	Gene names	Ankrd28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR42_MOUSE
NC score	0.704300 (rank : 17)	θ value	1.63604e-09 (rank : 92)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	283
SwissProt Accessions	Q3V096, Q8BX55, Q8BZT3, Q8C0T6, Q8C0X5	Gene names	Ankrd42
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 42.

ANR28_HUMAN
NC score	0.704120 (rank : 18)	θ value	9.90251e-15 (rank : 38)
Query Neighborhood Hits	368	Target Neighborhood Hits	314	Shared Neighborhood Hits	283
SwissProt Accessions	O15084, Q6ULS0, Q6ZT57	Gene names	ANKRD28, KIAA0379
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 28.

ANR52_MOUSE
NC score	0.701947 (rank : 19)	θ value	1.38178e-16 (rank : 24)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	284
SwissProt Accessions	Q8BTI7	Gene names	Ankrd52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

ANR52_HUMAN
NC score	0.700628 (rank : 20)	θ value	9.90251e-15 (rank : 39)
Query Neighborhood Hits	368	Target Neighborhood Hits	322	Shared Neighborhood Hits	284
SwissProt Accessions	Q8NB46	Gene names	ANKRD52
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 52.

FANK1_MOUSE
NC score	0.700519 (rank : 21)	θ value	1.63604e-09 (rank : 95)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	272
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANK1_HUMAN
NC score	0.699799 (rank : 22)	θ value	4.02038e-16 (rank : 27)
Query Neighborhood Hits	368	Target Neighborhood Hits	416	Shared Neighborhood Hits	285
SwissProt Accessions	P16157, O43400, Q13768, Q59FP2, Q8N604, Q99407	Gene names	ANK1, ANK
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin) (Ankyrin-R).

ANR39_HUMAN
NC score	0.699394 (rank : 23)	θ value	4.45536e-07 (rank : 158)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	273
SwissProt Accessions	Q53RE8, Q59FU2, Q8N5X5, Q9P0S5	Gene names	ANKRD39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ANK1_MOUSE
NC score	0.698916 (rank : 24)	θ value	6.85773e-16 (rank : 31)
Query Neighborhood Hits	368	Target Neighborhood Hits	430	Shared Neighborhood Hits	287
SwissProt Accessions	Q02357, P70440, P97446, P97941, Q3TZ35, Q3UH42, Q3UHP2, Q3UYY7, Q61302, Q61303, Q78E45	Gene names	Ank1, Ank-1
Domain Architecture
Description	Ankyrin-1 (Erythrocyte ankyrin).

FANK1_HUMAN
NC score	0.698710 (rank : 25)	θ value	2.36244e-08 (rank : 121)
Query Neighborhood Hits	368	Target Neighborhood Hits	326	Shared Neighborhood Hits	275
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

INVS_HUMAN
NC score	0.697852 (rank : 26)	θ value	6.00763e-12 (rank : 58)
Query Neighborhood Hits	368	Target Neighborhood Hits	455	Shared Neighborhood Hits	280
SwissProt Accessions	Q9Y283, Q5W0T6, Q8IVX8, Q9BRB9, Q9Y488, Q9Y498	Gene names	INVS, INV, NPHP2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning homolog) (Nephrocystin-2).

ANR39_MOUSE
NC score	0.697825 (rank : 27)	θ value	3.41135e-07 (rank : 154)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	272
SwissProt Accessions	Q9D2X0	Gene names	Ankrd39
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 39.

ASB8_MOUSE
NC score	0.697720 (rank : 28)	θ value	8.11959e-09 (rank : 108)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	274
SwissProt Accessions	Q91ZT9, Q8R178	Gene names	Asb8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR23_MOUSE
NC score	0.696759 (rank : 29)	θ value	5.26297e-08 (rank : 127)
Query Neighborhood Hits	368	Target Neighborhood Hits	296	Shared Neighborhood Hits	275
SwissProt Accessions	Q812A3	Gene names	Ankrd23, Darp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein).

ASB8_HUMAN
NC score	0.696198 (rank : 30)	θ value	1.38499e-08 (rank : 114)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	274
SwissProt Accessions	Q9H765, Q547Q2	Gene names	ASB8
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 8 (ASB-8).

ANR16_HUMAN
NC score	0.695952 (rank : 31)	θ value	0.000270298 (rank : 213)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	271
SwissProt Accessions	Q6P6B7, Q9NT01	Gene names	ANKRD16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 16.

ANKR1_HUMAN
NC score	0.695581 (rank : 32)	θ value	9.59137e-10 (rank : 84)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	272
SwissProt Accessions	Q15327, Q96LE7	Gene names	ANKRD1, C193, CARP, HA1A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein) (Cytokine-inducible nuclear protein) (C-193).

ANKR1_MOUSE
NC score	0.695468 (rank : 33)	θ value	2.79066e-09 (rank : 99)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	276
SwissProt Accessions	Q9CR42, O55014, Q3UIF7, Q3UJ39, Q792Q9	Gene names	Ankrd1, Carp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 1 (Cardiac ankyrin repeat protein).

ANKR2_MOUSE
NC score	0.695369 (rank : 34)	θ value	5.26297e-08 (rank : 126)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	279
SwissProt Accessions	Q9WV06	Gene names	Ankrd2, Arpp
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (mArpp).

ANKR2_HUMAN
NC score	0.694780 (rank : 35)	θ value	1.53129e-07 (rank : 137)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	282
SwissProt Accessions	Q9GZV1, Q5T456, Q8WUD7	Gene names	ANKRD2, ARPP
Domain Architecture
Description	Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp).

ANR49_MOUSE
NC score	0.694618 (rank : 36)	θ value	4.45536e-07 (rank : 159)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANR49_HUMAN
NC score	0.693172 (rank : 37)	θ value	3.41135e-07 (rank : 155)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	268
SwissProt Accessions	Q8WVL7, Q8NDF2, Q96JE5, Q9NXK7	Gene names	ANKRD49, FGIF
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor).

PA2G6_MOUSE
NC score	0.693138 (rank : 38)	θ value	6.64225e-11 (rank : 72)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	272
SwissProt Accessions	P97819, Q99LA9, Q9JK61	Gene names	Pla2g6
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

PP16A_MOUSE
NC score	0.693119 (rank : 39)	θ value	1.2105e-12 (rank : 51)
Query Neighborhood Hits	368	Target Neighborhood Hits	318	Shared Neighborhood Hits	277
SwissProt Accessions	Q923M0, Q4V9Z1	Gene names	Ppp1r16a, Mypt3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase targeting subunit 3).

MTPN_MOUSE
NC score	0.692395 (rank : 40)	θ value	1.99992e-07 (rank : 144)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	262
SwissProt Accessions	P62774, P80144, Q543M6, Q9DCN8	Gene names	Mtpn, Gcdp
Domain Architecture	No domain graphic available
Description	Myotrophin (Protein V-1) (Granule cell differentiation protein).

ANK3_HUMAN
NC score	0.692009 (rank : 41)	θ value	2.7842e-17 (rank : 23)
Query Neighborhood Hits	368	Target Neighborhood Hits	853	Shared Neighborhood Hits	295
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

ASB10_MOUSE
NC score	0.691867 (rank : 42)	θ value	2.36244e-08 (rank : 120)
Query Neighborhood Hits	368	Target Neighborhood Hits	301	Shared Neighborhood Hits	275
SwissProt Accessions	Q91ZT7	Gene names	Asb10
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

ASB10_HUMAN
NC score	0.691463 (rank : 43)	θ value	5.81887e-07 (rank : 161)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	273
SwissProt Accessions	Q8WXI3	Gene names	ASB10
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 10 (ASB-10).

PP16A_HUMAN
NC score	0.691244 (rank : 44)	θ value	4.16044e-13 (rank : 45)
Query Neighborhood Hits	368	Target Neighborhood Hits	340	Shared Neighborhood Hits	275
SwissProt Accessions	Q96I34	Gene names	PPP1R16A, MYPT3
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 16A (Myosin phosphatase- targeting subunit 3).

ANR23_HUMAN
NC score	0.691039 (rank : 45)	θ value	2.21117e-06 (rank : 169)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	274
SwissProt Accessions	Q86SG2, Q711K7, Q8NAJ7	Gene names	ANKRD23, DARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 23 (Diabetes-related ankyrin repeat protein) (Muscle ankyrin repeat protein 3).

MTPN_HUMAN
NC score	0.690219 (rank : 46)	θ value	2.61198e-07 (rank : 150)
Query Neighborhood Hits	368	Target Neighborhood Hits	269	Shared Neighborhood Hits	262
SwissProt Accessions	P58546	Gene names	MTPN
Domain Architecture
Description	Myotrophin (Protein V-1).

INVS_MOUSE
NC score	0.689934 (rank : 47)	θ value	1.74796e-11 (rank : 63)
Query Neighborhood Hits	368	Target Neighborhood Hits	609	Shared Neighborhood Hits	281
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

ASB2_HUMAN
NC score	0.689715 (rank : 48)	θ value	1.63604e-09 (rank : 93)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	276
SwissProt Accessions	Q96Q27, Q9NSU5, Q9Y567	Gene names	ASB2
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

PA2G6_HUMAN
NC score	0.689264 (rank : 49)	θ value	1.02475e-11 (rank : 61)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	270
SwissProt Accessions	O60733, O75645, Q8N452, Q9UG29, Q9UIT0, Q9Y671	Gene names	PLA2G6, IPLA2
Domain Architecture
Description	85 kDa calcium-independent phospholipase A2 (EC 3.1.1.4) (iPLA2) (CaI- PLA2) (Group VI phospholipase A2) (GVI PLA2).

BCL3_HUMAN
NC score	0.688567 (rank : 50)	θ value	1.80886e-08 (rank : 117)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	273
SwissProt Accessions	P20749	Gene names	BCL3
Domain Architecture
Description	B-cell lymphoma 3-encoded protein (Protein Bcl-3).

GABP2_MOUSE
NC score	0.687881 (rank : 51)	θ value	1.99992e-07 (rank : 143)
Query Neighborhood Hits	368	Target Neighborhood Hits	429	Shared Neighborhood Hits	289
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

PP16B_HUMAN
NC score	0.687258 (rank : 52)	θ value	5.43371e-13 (rank : 48)
Query Neighborhood Hits	368	Target Neighborhood Hits	307	Shared Neighborhood Hits	277
SwissProt Accessions	Q96T49, O94912, Q9NQG4	Gene names	PPP1R16B, ANKRD4, KIAA0823
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (hTIMAP) (CAAX box protein TIMAP) (Ankyrin repeat domain protein 4).

GABP3_MOUSE
NC score	0.686929 (rank : 53)	θ value	6.87365e-08 (rank : 131)
Query Neighborhood Hits	368	Target Neighborhood Hits	330	Shared Neighborhood Hits	272
SwissProt Accessions	P81069	Gene names	Gabpb2
Domain Architecture	No domain graphic available
Description	GA-binding protein beta-2-1 chain (GABP subunit beta-2-1) (GABPB2-1).

GABP2_HUMAN
NC score	0.686533 (rank : 54)	θ value	1.99992e-07 (rank : 142)
Query Neighborhood Hits	368	Target Neighborhood Hits	454	Shared Neighborhood Hits	288
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

ASZ1_HUMAN
NC score	0.686341 (rank : 55)	θ value	9.59137e-10 (rank : 85)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WWH4	Gene names	ASZ1, GASZ
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

ASB13_MOUSE
NC score	0.686183 (rank : 56)	θ value	1.99992e-07 (rank : 141)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	271
SwissProt Accessions	Q8VBX0	Gene names	Asb13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

ASB2_MOUSE
NC score	0.686173 (rank : 57)	θ value	1.63604e-09 (rank : 94)
Query Neighborhood Hits	368	Target Neighborhood Hits	321	Shared Neighborhood Hits	273
SwissProt Accessions	Q8K0L0, Q9CTH4, Q9WV73	Gene names	Asb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 2 (ASB-2).

ASZ1_MOUSE
NC score	0.685928 (rank : 58)	θ value	4.30538e-10 (rank : 79)
Query Neighborhood Hits	368	Target Neighborhood Hits	319	Shared Neighborhood Hits	278
SwissProt Accessions	Q8VD46, Q9JKQ7	Gene names	Asz1, Gasz
Domain Architecture
Description	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Germ cell-specific ankyrin, SAM and basic leucine zipper domain- containing protein).

PP16B_MOUSE
NC score	0.685716 (rank : 59)	θ value	4.16044e-13 (rank : 46)
Query Neighborhood Hits	368	Target Neighborhood Hits	302	Shared Neighborhood Hits	276
SwissProt Accessions	Q8VHQ3	Gene names	Ppp1r16b
Domain Architecture
Description	Protein phosphatase 1 regulatory inhibitor subunit 16B (TGF-beta- inhibited membrane-associated protein) (CAAX box protein TIMAP).

ASB13_HUMAN
NC score	0.685423 (rank : 60)	θ value	2.61198e-07 (rank : 147)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WXK3, Q96EP7, Q9H8Z1	Gene names	ASB13
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 13 (ASB-13).

BCL3_MOUSE
NC score	0.684955 (rank : 61)	θ value	2.13673e-09 (rank : 97)
Query Neighborhood Hits	368	Target Neighborhood Hits	388	Shared Neighborhood Hits	274
SwissProt Accessions	Q9Z2F6	Gene names	Bcl3
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 3-encoded protein homolog (Protein Bcl-3).

ANKS1_HUMAN
NC score	0.683884 (rank : 62)	θ value	1.68911e-14 (rank : 40)
Query Neighborhood Hits	368	Target Neighborhood Hits	438	Shared Neighborhood Hits	282
SwissProt Accessions	Q92625, Q5JYI9, Q5SYR2, Q86WQ7	Gene names	ANKS1A, ANKS1, KIAA0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A (Odin).

MYPT1_MOUSE
NC score	0.683353 (rank : 63)	θ value	2.13673e-09 (rank : 98)
Query Neighborhood Hits	368	Target Neighborhood Hits	539	Shared Neighborhood Hits	290
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

MIB1_HUMAN
NC score	0.682461 (rank : 64)	θ value	3.40345e-15 (rank : 32)
Query Neighborhood Hits	368	Target Neighborhood Hits	470	Shared Neighborhood Hits	281
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

MIB1_MOUSE
NC score	0.682062 (rank : 65)	θ value	3.40345e-15 (rank : 33)
Query Neighborhood Hits	368	Target Neighborhood Hits	471	Shared Neighborhood Hits	281
SwissProt Accessions	Q80SY4, Q5XK51, Q6IS57, Q6YI52, Q6ZPT8, Q8BNR1, Q8C6W2, Q921Q1	Gene names	Mib1, Dip1, Kiaa1323, Mib
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1).

MYPT2_HUMAN
NC score	0.681872 (rank : 66)	θ value	9.26847e-13 (rank : 49)
Query Neighborhood Hits	368	Target Neighborhood Hits	707	Shared Neighborhood Hits	301
SwissProt Accessions	O60237, Q8N179, Q9HCB7, Q9HCB8	Gene names	PPP1R12B, MYPT2
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12B (Myosin phosphatase- targeting subunit 2) (Myosin phosphatase target subunit 2).

ANKR5_MOUSE
NC score	0.680814 (rank : 67)	θ value	4.76016e-09 (rank : 104)
Query Neighborhood Hits	368	Target Neighborhood Hits	298	Shared Neighborhood Hits	274
SwissProt Accessions	Q9D2J7	Gene names	Ankrd5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

ANKS3_MOUSE
NC score	0.679954 (rank : 68)	θ value	1.80886e-08 (rank : 116)
Query Neighborhood Hits	368	Target Neighborhood Hits	355	Shared Neighborhood Hits	275
SwissProt Accessions	Q9CZK6, Q6ZPF6, Q80X46	Gene names	Anks3, Kiaa1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

TRPA1_MOUSE
NC score	0.678241 (rank : 69)	θ value	1.17247e-07 (rank : 136)
Query Neighborhood Hits	368	Target Neighborhood Hits	343	Shared Neighborhood Hits	282
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

ASB16_MOUSE
NC score	0.677854 (rank : 70)	θ value	2.79066e-09 (rank : 100)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	269
SwissProt Accessions	Q8VHS5, Q8BYT0	Gene names	Asb16
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

ANKR5_HUMAN
NC score	0.677599 (rank : 71)	θ value	1.38499e-08 (rank : 109)
Query Neighborhood Hits	368	Target Neighborhood Hits	297	Shared Neighborhood Hits	272
SwissProt Accessions	Q9NU02, Q9H6Y9	Gene names	ANKRD5
Domain Architecture
Description	Ankyrin repeat domain-containing protein 5.

OSBL2_MOUSE
NC score	0.676486 (rank : 72)	θ value	1.36195e-181 (rank : 4)
Query Neighborhood Hits	368	Target Neighborhood Hits	22	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BX94, Q3TCK8, Q8R0H8	Gene names	Osbpl2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

TRPA1_HUMAN
NC score	0.676334 (rank : 73)	θ value	1.99992e-07 (rank : 146)
Query Neighborhood Hits	368	Target Neighborhood Hits	339	Shared Neighborhood Hits	282
SwissProt Accessions	O75762	Gene names	TRPA1, ANKTM1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1) (Transformation sensitive-protein p120).

OSBL2_HUMAN
NC score	0.676232 (rank : 74)	θ value	1.23183e-182 (rank : 3)
Query Neighborhood Hits	368	Target Neighborhood Hits	23	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H1P3, Q9BZB1, Q9Y4B8	Gene names	OSBPL2, KIAA0772, ORP2
Domain Architecture
Description	Oxysterol-binding protein-related protein 2 (OSBP-related protein 2) (ORP-2).

ANKS3_HUMAN
NC score	0.676149 (rank : 75)	θ value	1.38499e-08 (rank : 110)
Query Neighborhood Hits	368	Target Neighborhood Hits	355	Shared Neighborhood Hits	274
SwissProt Accessions	Q6ZW76, Q8TF25	Gene names	ANKS3, KIAA1977
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 3.

BARD1_HUMAN
NC score	0.673894 (rank : 76)	θ value	2.69671e-12 (rank : 54)
Query Neighborhood Hits	368	Target Neighborhood Hits	427	Shared Neighborhood Hits	276
SwissProt Accessions	Q99728, O43574	Gene names	BARD1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANKS1_MOUSE
NC score	0.673248 (rank : 77)	θ value	2.43908e-13 (rank : 44)
Query Neighborhood Hits	368	Target Neighborhood Hits	453	Shared Neighborhood Hits	281
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

CT086_HUMAN
NC score	0.672594 (rank : 78)	θ value	1.69304e-06 (rank : 167)
Query Neighborhood Hits	368	Target Neighborhood Hits	277	Shared Neighborhood Hits	263
SwissProt Accessions	Q9BZ19, Q4VXE6	Gene names	C20orf86
Domain Architecture
Description	Putative uncharacterized protein C20orf86.

ANR10_MOUSE
NC score	0.670778 (rank : 79)	θ value	1.38499e-08 (rank : 111)
Query Neighborhood Hits	368	Target Neighborhood Hits	273	Shared Neighborhood Hits	260
SwissProt Accessions	Q99LW0	Gene names	Ankrd10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ASB15_HUMAN
NC score	0.670618 (rank : 80)	θ value	1.25267e-09 (rank : 90)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	272
SwissProt Accessions	Q8WXK1	Gene names	ASB15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

MIB2_HUMAN
NC score	0.669958 (rank : 81)	θ value	2.69671e-12 (rank : 55)
Query Neighborhood Hits	368	Target Neighborhood Hits	438	Shared Neighborhood Hits	276
SwissProt Accessions	Q96AX9, Q7Z437, Q8IY62, Q8N897, Q8N8R2, Q8N911, Q8NB36, Q8NCY1, Q8NG59, Q8NG60, Q8NG61, Q8NI59, Q8WYN1	Gene names	MIB2, SKD, ZZANK1
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Zinc finger ZZ type with ankyrin repeat domain protein 1) (Skeletrophin) (Novelzin) (Novel zinc finger protein) (Putative NF-kappa-B-activating protein 002N).

BARD1_MOUSE
NC score	0.669954 (rank : 82)	θ value	2.28291e-11 (rank : 64)
Query Neighborhood Hits	368	Target Neighborhood Hits	411	Shared Neighborhood Hits	270
SwissProt Accessions	O70445	Gene names	Bard1
Domain Architecture
Description	BRCA1-associated RING domain protein 1 (BARD-1).

ANR10_HUMAN
NC score	0.669323 (rank : 83)	θ value	3.08544e-08 (rank : 124)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	260
SwissProt Accessions	Q9NXR5	Gene names	ANKRD10
Domain Architecture
Description	Ankyrin repeat domain-containing protein 10.

ANRA2_HUMAN
NC score	0.669086 (rank : 84)	θ value	2.21117e-06 (rank : 170)
Query Neighborhood Hits	368	Target Neighborhood Hits	288	Shared Neighborhood Hits	271
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

MYPT1_HUMAN
NC score	0.668229 (rank : 85)	θ value	9.59137e-10 (rank : 86)
Query Neighborhood Hits	368	Target Neighborhood Hits	723	Shared Neighborhood Hits	305
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

ANKS6_MOUSE
NC score	0.668227 (rank : 86)	θ value	1.43324e-05 (rank : 184)
Query Neighborhood Hits	368	Target Neighborhood Hits	435	Shared Neighborhood Hits	278
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

ASB9_HUMAN
NC score	0.667656 (rank : 87)	θ value	2.79066e-09 (rank : 101)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	251
SwissProt Accessions	Q96DX5, Q9NWS5, Q9Y4T3	Gene names	ASB9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANRA2_MOUSE
NC score	0.667309 (rank : 88)	θ value	2.21117e-06 (rank : 171)
Query Neighborhood Hits	368	Target Neighborhood Hits	287	Shared Neighborhood Hits	271
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

ASB16_HUMAN
NC score	0.667082 (rank : 89)	θ value	1.87187e-05 (rank : 190)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	264
SwissProt Accessions	Q96NS5, Q8WXK0	Gene names	ASB16
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 16 (ASB-16).

RFXK_HUMAN
NC score	0.666994 (rank : 90)	θ value	1.87187e-05 (rank : 192)
Query Neighborhood Hits	368	Target Neighborhood Hits	282	Shared Neighborhood Hits	260
SwissProt Accessions	O14593, O95839	Gene names	RFXANK, ANKRA1, RFXB
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Ankyrin repeat family A protein 1).

ACBD6_MOUSE
NC score	0.666915 (rank : 91)	θ value	4.0297e-08 (rank : 125)
Query Neighborhood Hits	368	Target Neighborhood Hits	305	Shared Neighborhood Hits	277
SwissProt Accessions	Q9D061, Q3TMN7, Q9DCU4	Gene names	Acbd6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ANKS6_HUMAN
NC score	0.666584 (rank : 92)	θ value	2.44474e-05 (rank : 193)
Query Neighborhood Hits	368	Target Neighborhood Hits	411	Shared Neighborhood Hits	279
SwissProt Accessions	Q68DC2, Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2, Q8N9L6, Q96D62	Gene names	ANKS6, ANKRD14, SAMD6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6) (Ankyrin repeat domain-containing protein 14).

CDN2C_MOUSE
NC score	0.665330 (rank : 93)	θ value	0.000270298 (rank : 215)
Query Neighborhood Hits	368	Target Neighborhood Hits	270	Shared Neighborhood Hits	263
SwissProt Accessions	Q60772	Gene names	Cdkn2c
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

MIB2_MOUSE
NC score	0.664413 (rank : 94)	θ value	2.79066e-09 (rank : 102)
Query Neighborhood Hits	368	Target Neighborhood Hits	409	Shared Neighborhood Hits	270
SwissProt Accessions	Q8R516, Q52QU8, Q6PEF6, Q8C1N7, Q8VIB4	Gene names	Mib2, Skd
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB2 (EC 6.3.2.-) (Mind bomb homolog 2) (Mind bomb-2) (Skeletrophin) (Dystrophin-like protein) (Dyslike).

ACBD6_HUMAN
NC score	0.663393 (rank : 95)	θ value	1.99992e-07 (rank : 140)
Query Neighborhood Hits	368	Target Neighborhood Hits	304	Shared Neighborhood Hits	274
SwissProt Accessions	Q9BR61	Gene names	ACBD6
Domain Architecture	No domain graphic available
Description	Acyl-CoA-binding domain-containing protein 6.

ASB5_HUMAN
NC score	0.663306 (rank : 96)	θ value	1.38499e-08 (rank : 113)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	263
SwissProt Accessions	Q8WWX0	Gene names	ASB5
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

CDN2C_HUMAN
NC score	0.662040 (rank : 97)	θ value	0.000786445 (rank : 228)
Query Neighborhood Hits	368	Target Neighborhood Hits	262	Shared Neighborhood Hits	257
SwissProt Accessions	P42773, Q8TB83	Gene names	CDKN2C, CDKN6
Domain Architecture
Description	Cyclin-dependent kinase 6 inhibitor (p18-INK6) (Cyclin-dependent kinase 4 inhibitor C) (p18-INK4c).

ANR22_HUMAN
NC score	0.661970 (rank : 98)	θ value	6.43352e-06 (rank : 179)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	236
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

CSKI1_HUMAN
NC score	0.661490 (rank : 99)	θ value	5.25075e-16 (rank : 30)
Query Neighborhood Hits	368	Target Neighborhood Hits	997	Shared Neighborhood Hits	280
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI2_MOUSE
NC score	0.661343 (rank : 100)	θ value	3.89403e-11 (rank : 66)
Query Neighborhood Hits	368	Target Neighborhood Hits	812	Shared Neighborhood Hits	283
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ANKR7_HUMAN
NC score	0.661146 (rank : 101)	θ value	4.45536e-07 (rank : 157)
Query Neighborhood Hits	368	Target Neighborhood Hits	286	Shared Neighborhood Hits	267
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

CSKI1_MOUSE
NC score	0.660972 (rank : 102)	θ value	4.02038e-16 (rank : 28)
Query Neighborhood Hits	368	Target Neighborhood Hits	1031	Shared Neighborhood Hits	281
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

ASB11_MOUSE
NC score	0.660754 (rank : 103)	θ value	5.81887e-07 (rank : 162)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	251
SwissProt Accessions	Q9CQ31, Q3UJ13, Q9D0V1	Gene names	Asb11
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

CDN2D_HUMAN
NC score	0.659941 (rank : 104)	θ value	3.77169e-06 (rank : 176)
Query Neighborhood Hits	368	Target Neighborhood Hits	268	Shared Neighborhood Hits	258
SwissProt Accessions	P55273, Q13102, Q6FGE9	Gene names	CDKN2D
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

ASB14_MOUSE
NC score	0.659939 (rank : 105)	θ value	2.61198e-07 (rank : 148)
Query Neighborhood Hits	368	Target Neighborhood Hits	293	Shared Neighborhood Hits	266
SwissProt Accessions	Q8VHS7	Gene names	Asb14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ASB15_MOUSE
NC score	0.659926 (rank : 106)	θ value	1.17247e-07 (rank : 134)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	268
SwissProt Accessions	Q8VHS6	Gene names	Asb15
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 15 (ASB-15).

CSKI2_HUMAN
NC score	0.658821 (rank : 107)	θ value	8.67504e-11 (rank : 74)
Query Neighborhood Hits	368	Target Neighborhood Hits	747	Shared Neighborhood Hits	281
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ASB5_MOUSE
NC score	0.657939 (rank : 108)	θ value	1.17247e-07 (rank : 135)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	250
SwissProt Accessions	Q9D1A4	Gene names	Asb5
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 5 (ASB-5).

ASB11_HUMAN
NC score	0.657254 (rank : 109)	θ value	1.87187e-05 (rank : 189)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	253
SwissProt Accessions	Q8WXH4, Q3SYC4	Gene names	ASB11
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 11 (ASB-11).

ANR32_HUMAN
NC score	0.656675 (rank : 110)	θ value	1.38499e-08 (rank : 112)
Query Neighborhood Hits	368	Target Neighborhood Hits	270	Shared Neighborhood Hits	256
SwissProt Accessions	Q9BQI6	Gene names	ANKRD32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

IKBE_MOUSE
NC score	0.656411 (rank : 111)	θ value	2.88788e-06 (rank : 175)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	266
SwissProt Accessions	O54910, Q3U686, Q9CZZ9, Q9D7U3	Gene names	Nfkbie, Ikbe
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKB-E).

RN5A_HUMAN
NC score	0.655640 (rank : 112)	θ value	4.76016e-09 (rank : 105)
Query Neighborhood Hits	368	Target Neighborhood Hits	608	Shared Neighborhood Hits	276
SwissProt Accessions	Q05823	Gene names	RNASEL, RNS4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ASB1_MOUSE
NC score	0.655154 (rank : 113)	θ value	2.61198e-07 (rank : 149)
Query Neighborhood Hits	368	Target Neighborhood Hits	292	Shared Neighborhood Hits	265
SwissProt Accessions	Q9WV74	Gene names	Asb1
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

IKBA_HUMAN
NC score	0.655111 (rank : 114)	θ value	0.00102713 (rank : 232)
Query Neighborhood Hits	368	Target Neighborhood Hits	280	Shared Neighborhood Hits	265
SwissProt Accessions	P25963	Gene names	NFKBIA, IKBA, MAD3, NFKBI
Domain Architecture
Description	NF-kappa-B inhibitor alpha (Major histocompatibility complex enhancer- binding protein MAD3) (I-kappa-B-alpha) (IkappaBalpha) (IKB-alpha).

ASB1_HUMAN
NC score	0.654954 (rank : 115)	θ value	2.21117e-06 (rank : 172)
Query Neighborhood Hits	368	Target Neighborhood Hits	291	Shared Neighborhood Hits	267
SwissProt Accessions	Q9Y576, Q9ULS4	Gene names	ASB1, KIAA1146
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 1 (ASB-1).

ANR46_HUMAN
NC score	0.654760 (rank : 116)	θ value	0.000121331 (rank : 203)
Query Neighborhood Hits	368	Target Neighborhood Hits	281	Shared Neighborhood Hits	261
SwissProt Accessions	Q86W74, Q6P9B7	Gene names	ANKRD46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

RFXK_MOUSE
NC score	0.653684 (rank : 117)	θ value	0.00035302 (rank : 218)
Query Neighborhood Hits	368	Target Neighborhood Hits	273	Shared Neighborhood Hits	260
SwissProt Accessions	Q9Z205	Gene names	Rfxank, Rfxb, Tvl1
Domain Architecture
Description	DNA-binding protein RFXANK (Regulatory factor X subunit B) (RFX-B) (Regulatory factor X-associated ankyrin-containing protein) (Ankyrin repeat-containing adapter protein Tvl-1).

ASB9_MOUSE
NC score	0.652940 (rank : 118)	θ value	2.88788e-06 (rank : 174)
Query Neighborhood Hits	368	Target Neighborhood Hits	257	Shared Neighborhood Hits	246
SwissProt Accessions	Q91ZT8, Q9DAF7	Gene names	Asb9
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 9 (ASB-9).

ANR46_MOUSE
NC score	0.652611 (rank : 119)	θ value	3.19293e-05 (rank : 194)
Query Neighborhood Hits	368	Target Neighborhood Hits	274	Shared Neighborhood Hits	257
SwissProt Accessions	Q8BTZ5, Q1LZK9, Q8BV97	Gene names	Ankrd46
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S).

CDN2D_MOUSE
NC score	0.652090 (rank : 120)	θ value	9.29e-05 (rank : 202)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	254
SwissProt Accessions	Q60773, Q60794	Gene names	Cdkn2d
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor D (p19-INK4d).

EHMT1_HUMAN
NC score	0.650906 (rank : 121)	θ value	1.80886e-08 (rank : 119)
Query Neighborhood Hits	368	Target Neighborhood Hits	417	Shared Neighborhood Hits	279
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

ANR32_MOUSE
NC score	0.650621 (rank : 122)	θ value	1.17247e-07 (rank : 133)
Query Neighborhood Hits	368	Target Neighborhood Hits	285	Shared Neighborhood Hits	256
SwissProt Accessions	Q8R3P9, Q5XK30, Q8BHY5, Q921Y9	Gene names	Ankrd32
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 32.

ASB12_HUMAN
NC score	0.649769 (rank : 123)	θ value	4.92598e-06 (rank : 177)
Query Neighborhood Hits	368	Target Neighborhood Hits	263	Shared Neighborhood Hits	256
SwissProt Accessions	Q8WXK4, Q52LK4, Q6ISF9	Gene names	ASB12
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

ANK2_HUMAN
NC score	0.649679 (rank : 124)	θ value	1.63225e-17 (rank : 22)
Query Neighborhood Hits	368	Target Neighborhood Hits	1615	Shared Neighborhood Hits	306
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

AN36B_HUMAN
NC score	0.649410 (rank : 125)	θ value	1.80886e-08 (rank : 115)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	269
SwissProt Accessions	Q8N2N9, Q6IPR0	Gene names	ANKRD36B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36B.

IKBA_MOUSE
NC score	0.647773 (rank : 126)	θ value	0.00035302 (rank : 217)
Query Neighborhood Hits	368	Target Neighborhood Hits	283	Shared Neighborhood Hits	266
SwissProt Accessions	Q9Z1E3, Q80ZX5	Gene names	Nfkbia, Ikba
Domain Architecture	No domain graphic available
Description	NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkappaBalpha) (IKB- alpha).

ASB12_MOUSE
NC score	0.647707 (rank : 127)	θ value	4.92598e-06 (rank : 178)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	252
SwissProt Accessions	Q9D738	Gene names	Asb12
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 12 (ASB-12).

EHMT2_HUMAN
NC score	0.646123 (rank : 128)	θ value	3.29651e-10 (rank : 77)
Query Neighborhood Hits	368	Target Neighborhood Hits	498	Shared Neighborhood Hits	287
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ASB4_MOUSE
NC score	0.644546 (rank : 129)	θ value	0.000121331 (rank : 206)
Query Neighborhood Hits	368	Target Neighborhood Hits	265	Shared Neighborhood Hits	253
SwissProt Accessions	Q9WV71	Gene names	Asb4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

ASB4_HUMAN
NC score	0.644493 (rank : 130)	θ value	0.000121331 (rank : 205)
Query Neighborhood Hits	368	Target Neighborhood Hits	264	Shared Neighborhood Hits	253
SwissProt Accessions	Q9Y574, O14586	Gene names	ASB4
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 4 (ASB-4).

IKBE_HUMAN
NC score	0.643166 (rank : 131)	θ value	1.43324e-05 (rank : 186)
Query Neighborhood Hits	368	Target Neighborhood Hits	288	Shared Neighborhood Hits	261
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

IKBB_MOUSE
NC score	0.640292 (rank : 132)	θ value	1.69304e-06 (rank : 168)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	269
SwissProt Accessions	Q60778, Q9D6L5	Gene names	Nfkbib, Ikbb
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B).

ANR35_HUMAN
NC score	0.637624 (rank : 133)	θ value	6.21693e-09 (rank : 106)
Query Neighborhood Hits	368	Target Neighborhood Hits	784	Shared Neighborhood Hits	299
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

OSBL7_HUMAN
NC score	0.632773 (rank : 134)	θ value	1.11217e-74 (rank : 8)
Query Neighborhood Hits	368	Target Neighborhood Hits	71	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BZF2	Gene names	OSBPL7, ORP7
Domain Architecture
Description	Oxysterol-binding protein-related protein 7 (OSBP-related protein 7) (ORP-7).

EHMT2_MOUSE
NC score	0.632686 (rank : 135)	θ value	5.62301e-10 (rank : 82)
Query Neighborhood Hits	368	Target Neighborhood Hits	750	Shared Neighborhood Hits	286
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

ANR11_HUMAN
NC score	0.629238 (rank : 136)	θ value	3.52202e-12 (rank : 56)
Query Neighborhood Hits	368	Target Neighborhood Hits	1289	Shared Neighborhood Hits	297
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

IKBB_HUMAN
NC score	0.628507 (rank : 137)	θ value	0.000121331 (rank : 208)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	266
SwissProt Accessions	Q15653, Q96BJ7	Gene names	NFKBIB, IKBB, TRIP9
Domain Architecture
Description	NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkappaBbeta) (IKB-beta) (IKB-B) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9).

OSBP2_HUMAN
NC score	0.626779 (rank : 138)	θ value	1.35324e-88 (rank : 5)
Query Neighborhood Hits	368	Target Neighborhood Hits	154	Shared Neighborhood Hits	30
SwissProt Accessions	Q969R2, O60396, Q9BY96, Q9BZF0	Gene names	OSBP2, KIAA1664, ORP4, OSBPL4
Domain Architecture
Description	Oxysterol-binding protein 2 (Oxysterol-binding protein-related protein 4) (OSBP-related protein 4) (ORP-4).

ANKY2_HUMAN
NC score	0.626176 (rank : 139)	θ value	1.17247e-07 (rank : 132)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	259
SwissProt Accessions	Q8IV38, Q96BL3	Gene names	ANKMY2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

OSBP2_MOUSE
NC score	0.626172 (rank : 140)	θ value	2.38869e-85 (rank : 6)
Query Neighborhood Hits	368	Target Neighborhood Hits	150	Shared Neighborhood Hits	30
SwissProt Accessions	Q5QNQ6, Q8CF21	Gene names	Osbp2
Domain Architecture	No domain graphic available
Description	Oxysterol-binding protein 2.

OSBL3_MOUSE
NC score	0.624015 (rank : 141)	θ value	5.1662e-72 (rank : 12)
Query Neighborhood Hits	368	Target Neighborhood Hits	86	Shared Neighborhood Hits	36
SwissProt Accessions	Q9DBS9	Gene names	Osbpl3, Orp3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBP1_HUMAN
NC score	0.623133 (rank : 142)	θ value	7.19216e-82 (rank : 7)
Query Neighborhood Hits	368	Target Neighborhood Hits	180	Shared Neighborhood Hits	42
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

OSBL6_HUMAN
NC score	0.623126 (rank : 143)	θ value	3.57772e-73 (rank : 9)
Query Neighborhood Hits	368	Target Neighborhood Hits	101	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

POTE8_HUMAN
NC score	0.622483 (rank : 144)	θ value	9.92553e-07 (rank : 166)
Query Neighborhood Hits	368	Target Neighborhood Hits	337	Shared Neighborhood Hits	277
SwissProt Accessions	Q6S8J7, Q6S8J6	Gene names	POTE8
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 8.

OSBL3_HUMAN
NC score	0.620600 (rank : 145)	θ value	7.97034e-73 (rank : 10)
Query Neighborhood Hits	368	Target Neighborhood Hits	93	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H4L5, O14591, O43357, O43358, Q8N702, Q8N703, Q8N704, Q8NFH0, Q8NFH1, Q8NI12, Q8NI13, Q9BZF4, Q9UED6	Gene names	OSBPL3, KIAA0704, ORP3
Domain Architecture
Description	Oxysterol-binding protein-related protein 3 (OSBP-related protein 3) (ORP-3).

OSBL6_MOUSE
NC score	0.620517 (rank : 146)	θ value	7.97034e-73 (rank : 11)
Query Neighborhood Hits	368	Target Neighborhood Hits	105	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

ANFY1_MOUSE
NC score	0.619887 (rank : 147)	θ value	2.13673e-09 (rank : 96)
Query Neighborhood Hits	368	Target Neighborhood Hits	480	Shared Neighborhood Hits	283
SwissProt Accessions	Q810B6, O54807, Q80TG6, Q80UH8	Gene names	Ankfy1, Ankhzn, Kiaa1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

AN36A_HUMAN
NC score	0.619402 (rank : 148)	θ value	0.000158464 (rank : 209)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	262
SwissProt Accessions	Q6UX02, Q86X62	Gene names	ANKRD36, ANKRD36A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 36A.

ANFY1_HUMAN
NC score	0.618217 (rank : 149)	θ value	3.08544e-08 (rank : 123)
Query Neighborhood Hits	368	Target Neighborhood Hits	480	Shared Neighborhood Hits	281
SwissProt Accessions	Q9P2R3, Q9ULG5	Gene names	ANKFY1, ANKHZN, KIAA1255
Domain Architecture
Description	Ankyrin repeat and FYVE domain-containing protein 1 (Ankyrin repeats hooked to a zinc finger motif).

BCOR_MOUSE
NC score	0.616012 (rank : 150)	θ value	7.84624e-12 (rank : 59)
Query Neighborhood Hits	368	Target Neighborhood Hits	521	Shared Neighborhood Hits	270
SwissProt Accessions	Q8CGN4, Q6PDK5, Q6ZPM3, Q8BKF5, Q8CGN1, Q8CGN2, Q8CGN3	Gene names	Bcor, Kiaa1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

ANS4B_HUMAN
NC score	0.615819 (rank : 151)	θ value	0.000158464 (rank : 211)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	255
SwissProt Accessions	Q8N8V4	Gene names	ANKS4B, HARP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ZDH13_HUMAN
NC score	0.615686 (rank : 152)	θ value	3.29651e-10 (rank : 78)
Query Neighborhood Hits	368	Target Neighborhood Hits	322	Shared Neighborhood Hits	270
SwissProt Accessions	Q8IUH4, Q7Z2D3, Q86VK2, Q9NV30, Q9NV99	Gene names	ZDHHC13, HIP14L, HIP3RP
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein) (Huntingtin- interacting protein HIP3RP) (Putative NF-kappa-B-activating protein 209) (Putative MAPK-activating protein PM03).

ANR19_HUMAN
NC score	0.615423 (rank : 153)	θ value	0.000461057 (rank : 220)
Query Neighborhood Hits	368	Target Neighborhood Hits	276	Shared Neighborhood Hits	261
SwissProt Accessions	Q9H560	Gene names	ANKRD19
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 19.

ZDH17_HUMAN
NC score	0.614543 (rank : 154)	θ value	2.36244e-08 (rank : 122)
Query Neighborhood Hits	368	Target Neighborhood Hits	334	Shared Neighborhood Hits	270
SwissProt Accessions	Q8IUH5, O75407, Q7Z2I0, Q86W89, Q86YK0, Q9P088, Q9UPZ8	Gene names	ZDHHC17, HIP14, HIP3, KIAA0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14) (Huntingtin-interacting protein 3) (Huntingtin-interacting protein HYPH) (Putative NF-kappa-B-activating protein 205) (Putative MAPK- activating protein PM11).

RN5A_MOUSE
NC score	0.614107 (rank : 155)	θ value	6.21693e-09 (rank : 107)
Query Neighborhood Hits	368	Target Neighborhood Hits	899	Shared Neighborhood Hits	283
SwissProt Accessions	Q05921, Q9ERU7	Gene names	Rnasel, Rns4
Domain Architecture
Description	2-5A-dependent ribonuclease (EC 3.1.26.-) (2-5A-dependent RNase) (Ribonuclease L) (RNase L) (Ribonuclease 4).

ZDH13_MOUSE
NC score	0.613275 (rank : 156)	θ value	4.30538e-10 (rank : 81)
Query Neighborhood Hits	368	Target Neighborhood Hits	329	Shared Neighborhood Hits	272
SwissProt Accessions	Q9CWU2, Q3UK32, Q3UKV1	Gene names	Zdhhc13, Hip14l
Domain Architecture
Description	Probable palmitoyltransferase ZDHHC13 (EC 2.3.1.-) (Zinc finger DHHC domain-containing protein 13) (DHHC-13) (Huntingtin-interacting protein 14-related protein) (HIP14-related protein).

ZDH17_MOUSE
NC score	0.610581 (rank : 157)	θ value	5.26297e-08 (rank : 129)
Query Neighborhood Hits	368	Target Neighborhood Hits	328	Shared Neighborhood Hits	267
SwissProt Accessions	Q80TN5, Q8BJ08, Q8BYQ2, Q8BYQ6	Gene names	Zdhhc17, Hip14, Kiaa0946
Domain Architecture
Description	Palmitoyltransferase ZDHHC17 (EC 2.3.1.-) (Zinc finger DHHC domain- containing protein 17) (DHHC-17) (Huntingtin-interacting protein 14).

USH1G_MOUSE
NC score	0.609094 (rank : 158)	θ value	0.00665767 (rank : 251)
Query Neighborhood Hits	368	Target Neighborhood Hits	271	Shared Neighborhood Hits	254
SwissProt Accessions	Q80T11, Q80UG0	Gene names	Ush1g, Sans
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein homolog (Scaffold protein containing ankyrin repeats and SAM domain) (Jackson shaker protein).

USH1G_HUMAN
NC score	0.609028 (rank : 159)	θ value	0.00665767 (rank : 250)
Query Neighborhood Hits	368	Target Neighborhood Hits	267	Shared Neighborhood Hits	253
SwissProt Accessions	Q495M9, Q8N251	Gene names	USH1G, SANS
Domain Architecture	No domain graphic available
Description	Usher syndrome type-1G protein (Scaffold protein containing ankyrin repeats and SAM domain).

BCOR_HUMAN
NC score	0.608218 (rank : 160)	θ value	6.00763e-12 (rank : 57)
Query Neighborhood Hits	368	Target Neighborhood Hits	609	Shared Neighborhood Hits	271
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CTTB2_HUMAN
NC score	0.607772 (rank : 161)	θ value	1.80886e-08 (rank : 118)
Query Neighborhood Hits	368	Target Neighborhood Hits	1061	Shared Neighborhood Hits	316
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR12_HUMAN
NC score	0.607076 (rank : 162)	θ value	1.58096e-12 (rank : 52)
Query Neighborhood Hits	368	Target Neighborhood Hits	1081	Shared Neighborhood Hits	307
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

ANR37_HUMAN
NC score	0.606660 (rank : 163)	θ value	1.87187e-05 (rank : 188)
Query Neighborhood Hits	368	Target Neighborhood Hits	247	Shared Neighborhood Hits	237
SwissProt Accessions	Q7Z713	Gene names	ANKRD37, LPR2BP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37 (Low-density lipoprotein receptor-related protein 2-binding protein) (hLrp2bp).

ANR41_HUMAN
NC score	0.605605 (rank : 164)	θ value	0.00869519 (rank : 252)
Query Neighborhood Hits	368	Target Neighborhood Hits	332	Shared Neighborhood Hits	246
SwissProt Accessions	Q8NAG6, Q8N8J8	Gene names	ANKRD41
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 41.

ANS4B_MOUSE
NC score	0.603193 (rank : 165)	θ value	0.00102713 (rank : 230)
Query Neighborhood Hits	368	Target Neighborhood Hits	294	Shared Neighborhood Hits	254
SwissProt Accessions	Q8K3X6, Q9D8A5	Gene names	Anks4b, Harp
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 4B (Harmonin- interacting ankyrin repeat-containing protein) (Harp).

ANKY2_MOUSE
NC score	0.601087 (rank : 166)	θ value	3.41135e-07 (rank : 153)
Query Neighborhood Hits	368	Target Neighborhood Hits	316	Shared Neighborhood Hits	254
SwissProt Accessions	Q3TPE9, Q8BK14, Q8BYW5, Q8R3N4, Q921J1	Gene names	Ankmy2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and MYND domain-containing protein 2.

NFKB1_MOUSE
NC score	0.600386 (rank : 167)	θ value	3.89403e-11 (rank : 69)
Query Neighborhood Hits	368	Target Neighborhood Hits	300	Shared Neighborhood Hits	261
SwissProt Accessions	P25799, Q3TZE8, Q3V2V6, Q6TDG8, Q75ZL1, Q80Y21, Q8C712	Gene names	Nfkb1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) (NF-kappa-B1 p84/NF-kappa-B1 p98) [Contains: Nuclear factor NF- kappa-B p50 subunit].

NFKB1_HUMAN
NC score	0.600163 (rank : 168)	θ value	5.08577e-11 (rank : 71)
Query Neighborhood Hits	368	Target Neighborhood Hits	306	Shared Neighborhood Hits	266
SwissProt Accessions	P19838, Q68D84, Q86V43, Q8N4X7, Q9NZC0	Gene names	NFKB1
Domain Architecture
Description	Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP- 1) [Contains: Nuclear factor NF-kappa-B p50 subunit].

ANR47_MOUSE
NC score	0.590486 (rank : 169)	θ value	2.88788e-06 (rank : 173)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	258
SwissProt Accessions	Q9Z1P7	Gene names	Ankrd47, D17Ertd288e, Ng28
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

POT15_HUMAN
NC score	0.589508 (rank : 170)	θ value	1.99992e-07 (rank : 145)
Query Neighborhood Hits	368	Target Neighborhood Hits	893	Shared Neighborhood Hits	298
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

NFKB2_HUMAN
NC score	0.588939 (rank : 171)	θ value	5.26297e-08 (rank : 128)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	269
SwissProt Accessions	Q00653, Q04860, Q9BU75, Q9H471, Q9H472	Gene names	NFKB2, LYT10
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10) [Contains: Nuclear factor NF-kappa-B p52 subunit].

ANR21_HUMAN
NC score	0.588706 (rank : 172)	θ value	6.87365e-08 (rank : 130)
Query Neighborhood Hits	368	Target Neighborhood Hits	864	Shared Neighborhood Hits	298
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

ANR37_MOUSE
NC score	0.587788 (rank : 173)	θ value	0.000158464 (rank : 210)
Query Neighborhood Hits	368	Target Neighborhood Hits	237	Shared Neighborhood Hits	229
SwissProt Accessions	Q569N2, Q8CHS0	Gene names	Ankrd37
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 37.

ANR15_HUMAN
NC score	0.587039 (rank : 174)	θ value	0.000461057 (rank : 219)
Query Neighborhood Hits	368	Target Neighborhood Hits	478	Shared Neighborhood Hits	279
SwissProt Accessions	Q14678, Q5W0W0, Q8IY65, Q8WX74	Gene names	ANKRD15, KANK, KIAA0172
Domain Architecture
Description	Ankyrin repeat domain-containing protein 15 (Kidney ankyrin repeat- containing protein).

POT14_HUMAN
NC score	0.579913 (rank : 175)	θ value	6.43352e-06 (rank : 182)
Query Neighborhood Hits	368	Target Neighborhood Hits	403	Shared Neighborhood Hits	265
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

NFKB2_MOUSE
NC score	0.577766 (rank : 176)	θ value	1.53129e-07 (rank : 138)
Query Neighborhood Hits	368	Target Neighborhood Hits	326	Shared Neighborhood Hits	265
SwissProt Accessions	Q9WTK5	Gene names	Nfkb2
Domain Architecture
Description	Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) [Contains: Nuclear factor NF-kappa-B p52 subunit].

KRIT1_MOUSE
NC score	0.577202 (rank : 177)	θ value	6.43352e-06 (rank : 181)
Query Neighborhood Hits	368	Target Neighborhood Hits	258	Shared Neighborhood Hits	229
SwissProt Accessions	Q6S5J6, Q6VSV2, Q7TPR8, Q8C9Q6, Q9EPY2, Q9ERH0	Gene names	Krit1, Ccm1
Domain Architecture	No domain graphic available
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein homolog).

SHAN1_HUMAN
NC score	0.571445 (rank : 178)	θ value	3.41135e-07 (rank : 156)
Query Neighborhood Hits	368	Target Neighborhood Hits	1041	Shared Neighborhood Hits	269
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

KRIT1_HUMAN
NC score	0.565954 (rank : 179)	θ value	1.87187e-05 (rank : 191)
Query Neighborhood Hits	368	Target Neighborhood Hits	258	Shared Neighborhood Hits	222
SwissProt Accessions	O00522, O43894, Q506L6, Q6U276, Q75N19, Q9H180, Q9H264, Q9HAX5	Gene names	KRIT1, CCM1
Domain Architecture
Description	Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein).

CLPB_MOUSE
NC score	0.565735 (rank : 180)	θ value	0.00102713 (rank : 231)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	248
SwissProt Accessions	Q60649	Gene names	Clpb, Skd3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR47_HUMAN
NC score	0.564744 (rank : 181)	θ value	0.000121331 (rank : 204)
Query Neighborhood Hits	368	Target Neighborhood Hits	369	Shared Neighborhood Hits	254
SwissProt Accessions	Q6NY19, Q6NZI1, Q6ZQR3, Q8IUV2	Gene names	ANKRD47
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 47.

ASB6_MOUSE
NC score	0.559420 (rank : 182)	θ value	6.88961 (rank : 344)
Query Neighborhood Hits	368	Target Neighborhood Hits	264	Shared Neighborhood Hits	240
SwissProt Accessions	Q91ZU1, Q8VEC6	Gene names	Asb6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

SNCAP_HUMAN
NC score	0.558353 (rank : 183)	θ value	1.38821 (rank : 310)
Query Neighborhood Hits	368	Target Neighborhood Hits	313	Shared Neighborhood Hits	236
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

ASB6_HUMAN
NC score	0.555919 (rank : 184)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	368	Target Neighborhood Hits	256	Shared Neighborhood Hits	240
SwissProt Accessions	Q9NWX5	Gene names	ASB6
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 6 (ASB-6).

ANR25_HUMAN
NC score	0.552697 (rank : 185)	θ value	5.44631e-05 (rank : 198)
Query Neighborhood Hits	368	Target Neighborhood Hits	350	Shared Neighborhood Hits	254
SwissProt Accessions	Q63ZY3, Q3KQZ3, Q6GUF5, Q9H8S4, Q9NUP0, Q9P210	Gene names	ANKRD25, KIAA1518, SIP
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25 (SRC-1-interacting protein) (SRC1-interacting protein).

POT22_HUMAN
NC score	0.543822 (rank : 186)	θ value	0.000602161 (rank : 225)
Query Neighborhood Hits	368	Target Neighborhood Hits	266	Shared Neighborhood Hits	251
SwissProt Accessions	Q6S545	Gene names	ACTBL1, POTE22
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 22.

CD2A1_MOUSE
NC score	0.543585 (rank : 187)	θ value	1.81305 (rank : 314)
Query Neighborhood Hits	368	Target Neighborhood Hits	206	Shared Neighborhood Hits	198
SwissProt Accessions	P51480, O89088, P97510, P97937, Q6PEA2, Q78E39, Q78E57, Q792X7, Q9QWH6, Q9QWH7, Q9QWH8	Gene names	Cdkn2a, P16ink4a
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a).

OSTF1_MOUSE
NC score	0.541319 (rank : 188)	θ value	2.61198e-07 (rank : 152)
Query Neighborhood Hits	368	Target Neighborhood Hits	467	Shared Neighborhood Hits	253
SwissProt Accessions	Q62422, Q3UF05	Gene names	Ostf1, Sh3d3, Sh3p2
Domain Architecture
Description	Osteoclast-stimulating factor 1 (SH3 domain protein 3).

ANR25_MOUSE
NC score	0.540597 (rank : 189)	θ value	0.000270298 (rank : 214)
Query Neighborhood Hits	368	Target Neighborhood Hits	398	Shared Neighborhood Hits	254
SwissProt Accessions	Q8BX02, Q8BLD5, Q91Z35	Gene names	Ankrd25
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 25.

ANR33_MOUSE
NC score	0.540301 (rank : 190)	θ value	0.163984 (rank : 276)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	220
SwissProt Accessions	Q8BXP5, Q8BXP4, Q8R1Z1	Gene names	Ankrd33
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

A20A3_HUMAN
NC score	0.536173 (rank : 191)	θ value	5.44631e-05 (rank : 196)
Query Neighborhood Hits	368	Target Neighborhood Hits	692	Shared Neighborhood Hits	288
SwissProt Accessions	Q5VUR7	Gene names	ANKRD20A3
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A3.

A20A1_HUMAN
NC score	0.535523 (rank : 192)	θ value	5.44631e-05 (rank : 195)
Query Neighborhood Hits	368	Target Neighborhood Hits	698	Shared Neighborhood Hits	290
SwissProt Accessions	Q5TYW2, Q9H0H6	Gene names	ANKRD20A1, ANKRD20A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A1.

A20A2_HUMAN
NC score	0.534859 (rank : 193)	θ value	7.1131e-05 (rank : 199)
Query Neighborhood Hits	368	Target Neighborhood Hits	716	Shared Neighborhood Hits	295
SwissProt Accessions	Q4UJ75	Gene names	ANKRD20A2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A2.

MPP8_HUMAN
NC score	0.533675 (rank : 194)	θ value	0.00390308 (rank : 243)
Query Neighborhood Hits	368	Target Neighborhood Hits	948	Shared Neighborhood Hits	272
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

A20A4_HUMAN
NC score	0.532601 (rank : 195)	θ value	5.44631e-05 (rank : 197)
Query Neighborhood Hits	368	Target Neighborhood Hits	710	Shared Neighborhood Hits	290
SwissProt Accessions	Q5SQ80	Gene names	ANKRD20A4
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 20A4.

ANR33_HUMAN
NC score	0.531032 (rank : 196)	θ value	0.62314 (rank : 295)
Query Neighborhood Hits	368	Target Neighborhood Hits	215	Shared Neighborhood Hits	209
SwissProt Accessions	Q7Z3H0, Q5K619, Q5K621, Q5K622, Q5K623, Q5K624, Q6ZUN0	Gene names	ANKRD33, C12orf7
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 33.

ANR40_HUMAN
NC score	0.530052 (rank : 197)	θ value	6.43352e-06 (rank : 180)
Query Neighborhood Hits	368	Target Neighborhood Hits	224	Shared Neighborhood Hits	199
SwissProt Accessions	Q6AI12, Q96E32	Gene names	ANKRD40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

OSTF1_HUMAN
NC score	0.527067 (rank : 198)	θ value	7.59969e-07 (rank : 163)
Query Neighborhood Hits	368	Target Neighborhood Hits	466	Shared Neighborhood Hits	252
SwissProt Accessions	Q92882, Q5W126, Q96IJ4	Gene names	OSTF1
Domain Architecture
Description	Osteoclast-stimulating factor 1.

ANR38_HUMAN
NC score	0.526945 (rank : 199)	θ value	0.0193708 (rank : 258)
Query Neighborhood Hits	368	Target Neighborhood Hits	443	Shared Neighborhood Hits	247
SwissProt Accessions	Q5T7N3, Q6P9A0, Q86T71, Q86VE6, Q8NAX3	Gene names	ANKRD38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

ANR40_MOUSE
NC score	0.526799 (rank : 200)	θ value	1.43324e-05 (rank : 185)
Query Neighborhood Hits	368	Target Neighborhood Hits	228	Shared Neighborhood Hits	203
SwissProt Accessions	Q5SUE8, Q8R595, Q9CU71	Gene names	Ankrd40
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 40.

RAI14_HUMAN
NC score	0.524124 (rank : 201)	θ value	1.25267e-09 (rank : 91)
Query Neighborhood Hits	368	Target Neighborhood Hits	1367	Shared Neighborhood Hits	324
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

OSBL5_HUMAN
NC score	0.522859 (rank : 202)	θ value	3.17079e-29 (rank : 14)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

OSBL5_MOUSE
NC score	0.521187 (rank : 203)	θ value	5.40856e-29 (rank : 15)
Query Neighborhood Hits	368	Target Neighborhood Hits	77	Shared Neighborhood Hits	23
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

CDN2B_MOUSE
NC score	0.515205 (rank : 204)	θ value	4.03905 (rank : 329)
Query Neighborhood Hits	368	Target Neighborhood Hits	201	Shared Neighborhood Hits	194
SwissProt Accessions	P55271	Gene names	Cdkn2b
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b).

OSBL8_HUMAN
NC score	0.512865 (rank : 205)	θ value	7.29293e-34 (rank : 13)
Query Neighborhood Hits	368	Target Neighborhood Hits	289	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

ANR43_HUMAN
NC score	0.511277 (rank : 206)	θ value	0.00134147 (rank : 234)
Query Neighborhood Hits	368	Target Neighborhood Hits	209	Shared Neighborhood Hits	202
SwissProt Accessions	Q2M3V2, Q8NAE7	Gene names	ANKRD43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

ANR43_MOUSE
NC score	0.507500 (rank : 207)	θ value	0.00102713 (rank : 229)
Query Neighborhood Hits	368	Target Neighborhood Hits	214	Shared Neighborhood Hits	205
SwissProt Accessions	Q8BLS7	Gene names	Ankrd43
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 43.

CLPB_HUMAN
NC score	0.506063 (rank : 208)	θ value	1.09739e-05 (rank : 183)
Query Neighborhood Hits	368	Target Neighborhood Hits	265	Shared Neighborhood Hits	233
SwissProt Accessions	Q9H078, Q8ND11, Q9H8Y0	Gene names	CLPB, SKD3
Domain Architecture
Description	Caseinolytic peptidase B protein homolog (Suppressor of potassium transport defect 3).

ANR38_MOUSE
NC score	0.505424 (rank : 209)	θ value	0.0736092 (rank : 268)
Query Neighborhood Hits	368	Target Neighborhood Hits	512	Shared Neighborhood Hits	249
SwissProt Accessions	Q6P9J5, Q8BV03	Gene names	Ankrd38
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 38.

OSB10_HUMAN
NC score	0.503569 (rank : 210)	θ value	3.39556e-23 (rank : 17)
Query Neighborhood Hits	368	Target Neighborhood Hits	55	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BXB5, Q9BTU5	Gene names	OSBPL10, ORP10, OSBP9
Domain Architecture
Description	Oxysterol-binding protein-related protein 10 (OSBP-related protein 10) (ORP-10).

OSBL9_HUMAN
NC score	0.503386 (rank : 211)	θ value	4.43474e-23 (rank : 18)
Query Neighborhood Hits	368	Target Neighborhood Hits	138	Shared Neighborhood Hits	38
SwissProt Accessions	Q96SU4, Q9H9X2	Gene names	OSBPL9, ORP9, OSBP4
Domain Architecture
Description	Oxysterol-binding protein-related protein 9 (OSBP-related protein 9) (ORP-9).

ANR18_HUMAN
NC score	0.498090 (rank : 212)	θ value	9.29e-05 (rank : 200)
Query Neighborhood Hits	368	Target Neighborhood Hits	1106	Shared Neighborhood Hits	295
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RAI14_MOUSE
NC score	0.496393 (rank : 213)	θ value	2.98157e-11 (rank : 65)
Query Neighborhood Hits	368	Target Neighborhood Hits	1505	Shared Neighborhood Hits	320
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

HECD1_HUMAN
NC score	0.493646 (rank : 214)	θ value	0.000461057 (rank : 221)
Query Neighborhood Hits	368	Target Neighborhood Hits	371	Shared Neighborhood Hits	267
SwissProt Accessions	Q9ULT8, Q6P445, Q86VJ1, Q96F34, Q9UFZ7	Gene names	HECTD1, KIAA1131
Domain Architecture	No domain graphic available
Description	E3 ubiquitin-protein ligase HECTD1 (HECT domain-containing protein 1) (E3 ligase for inhibin receptor) (EULIR).

OSB11_MOUSE
NC score	0.489649 (rank : 215)	θ value	1.80048e-24 (rank : 16)
Query Neighborhood Hits	368	Target Neighborhood Hits	71	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CI95	Gene names	Osbpl11
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

NUD12_MOUSE
NC score	0.486403 (rank : 216)	θ value	0.00102713 (rank : 233)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	220
SwissProt Accessions	Q9DCN1, Q6PFA5	Gene names	Nudt12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

CDN2B_HUMAN
NC score	0.483951 (rank : 217)	θ value	0.47712 (rank : 290)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	190
SwissProt Accessions	P42772, Q6FI09	Gene names	CDKN2B, MTS2
Domain Architecture
Description	Cyclin-dependent kinase 4 inhibitor B (p14-INK4b) (p15-INK4b) (p15INK4B) (Multiple tumor suppressor 2) (MTS2).

OSB11_HUMAN
NC score	0.482895 (rank : 218)	θ value	8.36355e-22 (rank : 19)
Query Neighborhood Hits	368	Target Neighborhood Hits	60	Shared Neighborhood Hits	26
SwissProt Accessions	Q9BXB4	Gene names	OSBPL11, ORP11, OSBP12
Domain Architecture
Description	Oxysterol-binding protein-related protein 11 (OSBP-related protein 11) (ORP-11).

ABTB2_HUMAN
NC score	0.479317 (rank : 219)	θ value	0.000602161 (rank : 223)
Query Neighborhood Hits	368	Target Neighborhood Hits	391	Shared Neighborhood Hits	237
SwissProt Accessions	Q8N961, Q6MZW4, Q8NB44	Gene names	ABTB2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

CD2A1_HUMAN
NC score	0.477043 (rank : 220)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	189
SwissProt Accessions	P42771, O95440, Q15191, Q5VVJ5, Q96B52, Q9NP05	Gene names	CDKN2A, CDKN2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4) (p16-INK4a) (p16INK4A) (Multiple tumor suppressor 1) (MTS1).

ABTB2_MOUSE
NC score	0.471021 (rank : 221)	θ value	0.00035302 (rank : 216)
Query Neighborhood Hits	368	Target Neighborhood Hits	414	Shared Neighborhood Hits	238
SwissProt Accessions	Q7TQI7	Gene names	Abtb2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 2.

AN30A_HUMAN
NC score	0.466262 (rank : 222)	θ value	0.000602161 (rank : 224)
Query Neighborhood Hits	368	Target Neighborhood Hits	1119	Shared Neighborhood Hits	297
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR45_MOUSE
NC score	0.460625 (rank : 223)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	368	Target Neighborhood Hits	204	Shared Neighborhood Hits	189
SwissProt Accessions	Q810N6	Gene names	Ankrd45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

NUD12_HUMAN
NC score	0.459620 (rank : 224)	θ value	0.000461057 (rank : 222)
Query Neighborhood Hits	368	Target Neighborhood Hits	222	Shared Neighborhood Hits	201
SwissProt Accessions	Q9BQG2, Q8TAL7	Gene names	NUDT12
Domain Architecture	No domain graphic available
Description	Peroxisomal NADH pyrophosphatase NUDT12 (EC 3.6.1.22) (Nucleoside diphosphate-linked moiety X motif 12) (Nudix motif 12).

ASPP2_HUMAN
NC score	0.459343 (rank : 225)	θ value	0.00869519 (rank : 253)
Query Neighborhood Hits	368	Target Neighborhood Hits	1156	Shared Neighborhood Hits	301
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

ANKK1_HUMAN
NC score	0.453634 (rank : 226)	θ value	1.2105e-12 (rank : 50)
Query Neighborhood Hits	368	Target Neighborhood Hits	1075	Shared Neighborhood Hits	286
SwissProt Accessions	Q8NFD2	Gene names	ANKK1, PKK2
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1) (Protein kinase PKK2) (X-kinase) (SgK288).

ASPP1_HUMAN
NC score	0.449781 (rank : 227)	θ value	0.00175202 (rank : 236)
Query Neighborhood Hits	368	Target Neighborhood Hits	956	Shared Neighborhood Hits	289
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

IASPP_HUMAN
NC score	0.447497 (rank : 228)	θ value	0.0736092 (rank : 269)
Query Neighborhood Hits	368	Target Neighborhood Hits	688	Shared Neighborhood Hits	259
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

RIPK4_HUMAN
NC score	0.444775 (rank : 229)	θ value	6.64225e-11 (rank : 73)
Query Neighborhood Hits	368	Target Neighborhood Hits	1094	Shared Neighborhood Hits	290
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

AN13B_MOUSE
NC score	0.442563 (rank : 230)	θ value	0.000786445 (rank : 227)
Query Neighborhood Hits	368	Target Neighborhood Hits	276	Shared Neighborhood Hits	250
SwissProt Accessions	Q5F259, Q6IR40	Gene names	Ankrd13b
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

AN13B_HUMAN
NC score	0.442305 (rank : 231)	θ value	0.000786445 (rank : 226)
Query Neighborhood Hits	368	Target Neighborhood Hits	265	Shared Neighborhood Hits	250
SwissProt Accessions	Q86YJ7, Q8N7S9	Gene names	ANKRD13B
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13B.

ANKK1_MOUSE
NC score	0.440662 (rank : 232)	θ value	2.0648e-12 (rank : 53)
Query Neighborhood Hits	368	Target Neighborhood Hits	1072	Shared Neighborhood Hits	285
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ILK2_HUMAN
NC score	0.439323 (rank : 233)	θ value	3.89403e-11 (rank : 68)
Query Neighborhood Hits	368	Target Neighborhood Hits	848	Shared Neighborhood Hits	272
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

CENB5_HUMAN
NC score	0.438143 (rank : 234)	θ value	0.00665767 (rank : 248)
Query Neighborhood Hits	368	Target Neighborhood Hits	395	Shared Neighborhood Hits	264
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

AN13C_HUMAN
NC score	0.437992 (rank : 235)	θ value	0.00390308 (rank : 241)
Query Neighborhood Hits	368	Target Neighborhood Hits	241	Shared Neighborhood Hits	234
SwissProt Accessions	Q8N6S4, Q5VYH4, Q5VYH5, Q6PJE4, Q9H0N9	Gene names	ANKRD13C
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASPP1_MOUSE
NC score	0.434464 (rank : 236)	θ value	0.00175202 (rank : 237)
Query Neighborhood Hits	368	Target Neighborhood Hits	1244	Shared Neighborhood Hits	292
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CENB1_HUMAN
NC score	0.433461 (rank : 237)	θ value	0.125558 (rank : 274)
Query Neighborhood Hits	368	Target Neighborhood Hits	383	Shared Neighborhood Hits	258
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

TRPV6_MOUSE
NC score	0.432264 (rank : 238)	θ value	0.0736092 (rank : 270)
Query Neighborhood Hits	368	Target Neighborhood Hits	284	Shared Neighborhood Hits	245
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

ANR45_HUMAN
NC score	0.431809 (rank : 239)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	368	Target Neighborhood Hits	201	Shared Neighborhood Hits	183
SwissProt Accessions	Q5TZF3, Q6ZST1	Gene names	ANKRD45
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 45.

AN13C_MOUSE
NC score	0.429599 (rank : 240)	θ value	0.00390308 (rank : 242)
Query Neighborhood Hits	368	Target Neighborhood Hits	242	Shared Neighborhood Hits	230
SwissProt Accessions	Q3UX43, Q6P1G4	Gene names	Ankrd13c
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13C.

ASB14_HUMAN
NC score	0.428821 (rank : 241)	θ value	0.21417 (rank : 279)
Query Neighborhood Hits	368	Target Neighborhood Hits	187	Shared Neighborhood Hits	171
SwissProt Accessions	Q8WXK2	Gene names	ASB14
Domain Architecture
Description	Ankyrin repeat and SOCS box protein 14 (ASB-14).

ANKY1_HUMAN
NC score	0.427921 (rank : 242)	θ value	1.38821 (rank : 309)
Query Neighborhood Hits	368	Target Neighborhood Hits	248	Shared Neighborhood Hits	202
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

ILK_MOUSE
NC score	0.424443 (rank : 243)	θ value	7.84624e-12 (rank : 60)
Query Neighborhood Hits	368	Target Neighborhood Hits	858	Shared Neighborhood Hits	272
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILK1_HUMAN
NC score	0.424291 (rank : 244)	θ value	3.89403e-11 (rank : 67)
Query Neighborhood Hits	368	Target Neighborhood Hits	857	Shared Neighborhood Hits	272
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

CENB2_HUMAN
NC score	0.418129 (rank : 245)	θ value	0.365318 (rank : 285)
Query Neighborhood Hits	368	Target Neighborhood Hits	425	Shared Neighborhood Hits	259
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

GLSL_HUMAN
NC score	0.418077 (rank : 246)	θ value	0.0330416 (rank : 260)
Query Neighborhood Hits	368	Target Neighborhood Hits	211	Shared Neighborhood Hits	197
SwissProt Accessions	Q9UI32, Q9NYY2, Q9UI31	Gene names	GLS2, GA
Domain Architecture
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GLSL_MOUSE
NC score	0.407224 (rank : 247)	θ value	0.0431538 (rank : 264)
Query Neighborhood Hits	368	Target Neighborhood Hits	212	Shared Neighborhood Hits	198
SwissProt Accessions	Q571F8	Gene names	Gls2, Kiaa4146
Domain Architecture	No domain graphic available
Description	Glutaminase liver isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (L-glutaminase).

GIT2_MOUSE
NC score	0.405070 (rank : 248)	θ value	0.00869519 (rank : 255)
Query Neighborhood Hits	368	Target Neighborhood Hits	323	Shared Neighborhood Hits	248
SwissProt Accessions	Q9JLQ2	Gene names	Git2
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT2) (CAT-2).

IASPP_MOUSE
NC score	0.401845 (rank : 249)	θ value	0.365318 (rank : 287)
Query Neighborhood Hits	368	Target Neighborhood Hits	1024	Shared Neighborhood Hits	260
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

UACA_HUMAN
NC score	0.401255 (rank : 250)	θ value	0.00134147 (rank : 235)
Query Neighborhood Hits	368	Target Neighborhood Hits	1622	Shared Neighborhood Hits	321
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

GIT1_HUMAN
NC score	0.394491 (rank : 251)	θ value	0.0431538 (rank : 262)
Query Neighborhood Hits	368	Target Neighborhood Hits	336	Shared Neighborhood Hits	251
SwissProt Accessions	Q9Y2X7, Q86SS0, Q9BRJ4	Gene names	GIT1
Domain Architecture
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1) (Cool-associated and tyrosine-phosphorylated protein 1) (Cat-1).

GIT1_MOUSE
NC score	0.393554 (rank : 252)	θ value	0.0431538 (rank : 263)
Query Neighborhood Hits	368	Target Neighborhood Hits	341	Shared Neighborhood Hits	251
SwissProt Accessions	Q68FF6	Gene names	Git1
Domain Architecture	No domain graphic available
Description	ARF GTPase-activating protein GIT1 (G protein-coupled receptor kinase- interactor 1) (GRK-interacting protein 1).

AN13A_HUMAN
NC score	0.389548 (rank : 253)	θ value	0.00665767 (rank : 247)
Query Neighborhood Hits	368	Target Neighborhood Hits	243	Shared Neighborhood Hits	215
SwissProt Accessions	Q8IZ07, O60736	Gene names	ANKRD13A, ANKRD13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A (Protein KE03).

TRPV5_MOUSE
NC score	0.388929 (rank : 254)	θ value	0.163984 (rank : 278)
Query Neighborhood Hits	368	Target Neighborhood Hits	278	Shared Neighborhood Hits	238
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

UACA_MOUSE
NC score	0.382253 (rank : 255)	θ value	0.00390308 (rank : 244)
Query Neighborhood Hits	368	Target Neighborhood Hits	1620	Shared Neighborhood Hits	319
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

GLSK_HUMAN
NC score	0.380558 (rank : 256)	θ value	1.81305 (rank : 316)
Query Neighborhood Hits	368	Target Neighborhood Hits	204	Shared Neighborhood Hits	186
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

ANR26_MOUSE
NC score	0.380246 (rank : 257)	θ value	9.92553e-07 (rank : 164)
Query Neighborhood Hits	368	Target Neighborhood Hits	1554	Shared Neighborhood Hits	315
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

NOTC4_MOUSE
NC score	0.379184 (rank : 258)	θ value	7.34386e-10 (rank : 83)
Query Neighborhood Hits	368	Target Neighborhood Hits	872	Shared Neighborhood Hits	278
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

DDFL1_MOUSE
NC score	0.378350 (rank : 259)	θ value	0.00869519 (rank : 254)
Query Neighborhood Hits	368	Target Neighborhood Hits	324	Shared Neighborhood Hits	251
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

NOTC4_HUMAN
NC score	0.375414 (rank : 260)	θ value	4.30538e-10 (rank : 80)
Query Neighborhood Hits	368	Target Neighborhood Hits	905	Shared Neighborhood Hits	281
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

GIT2_HUMAN
NC score	0.373075 (rank : 261)	θ value	0.0563607 (rank : 267)
Query Neighborhood Hits	368	Target Neighborhood Hits	381	Shared Neighborhood Hits	252
SwissProt Accessions	Q14161, Q86U59, Q96CI2, Q9BV91, Q9Y5V2	Gene names	GIT2, KIAA0148
Domain Architecture
Description	ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase- interactor 2) (GRK-interacting protein 2) (Cool-interacting tyrosine- phosphorylated protein 2) (CAT2) (CAT-2).

AN13A_MOUSE
NC score	0.371779 (rank : 262)	θ value	0.00509761 (rank : 245)
Query Neighborhood Hits	368	Target Neighborhood Hits	226	Shared Neighborhood Hits	209
SwissProt Accessions	Q80UP5, Q2VPQ7, Q6P7F2	Gene names	Ankrd13a, Ankrd13
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13A.

TRPV5_HUMAN
NC score	0.367255 (rank : 263)	θ value	0.0431538 (rank : 265)
Query Neighborhood Hits	368	Target Neighborhood Hits	261	Shared Neighborhood Hits	219
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

ANR26_HUMAN
NC score	0.363974 (rank : 264)	θ value	5.81887e-07 (rank : 160)
Query Neighborhood Hits	368	Target Neighborhood Hits	1614	Shared Neighborhood Hits	322
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TRPV6_HUMAN
NC score	0.362006 (rank : 265)	θ value	0.365318 (rank : 289)
Query Neighborhood Hits	368	Target Neighborhood Hits	262	Shared Neighborhood Hits	219
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TNI3K_HUMAN
NC score	0.357117 (rank : 266)	θ value	3.89403e-11 (rank : 70)
Query Neighborhood Hits	368	Target Neighborhood Hits	1084	Shared Neighborhood Hits	287
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
NC score	0.355568 (rank : 267)	θ value	4.16044e-13 (rank : 47)
Query Neighborhood Hits	368	Target Neighborhood Hits	1079	Shared Neighborhood Hits	288
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

NOTC3_MOUSE
NC score	0.343870 (rank : 268)	θ value	9.59137e-10 (rank : 89)
Query Neighborhood Hits	368	Target Neighborhood Hits	975	Shared Neighborhood Hits	283
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC1_HUMAN
NC score	0.341859 (rank : 269)	θ value	9.59137e-10 (rank : 87)
Query Neighborhood Hits	368	Target Neighborhood Hits	906	Shared Neighborhood Hits	278
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
NC score	0.341847 (rank : 270)	θ value	9.59137e-10 (rank : 88)
Query Neighborhood Hits	368	Target Neighborhood Hits	1062	Shared Neighborhood Hits	281
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_HUMAN
NC score	0.337414 (rank : 271)	θ value	1.53129e-07 (rank : 139)
Query Neighborhood Hits	368	Target Neighborhood Hits	1113	Shared Neighborhood Hits	275
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CT012_MOUSE
NC score	0.335583 (rank : 272)	θ value	8.99809 (rank : 360)
Query Neighborhood Hits	368	Target Neighborhood Hits	229	Shared Neighborhood Hits	174
SwissProt Accessions	Q8C008, Q8C060	Gene names
Domain Architecture	No domain graphic available
Description	Protein C20orf12 homolog.

NOTC2_MOUSE
NC score	0.335567 (rank : 273)	θ value	2.61198e-07 (rank : 151)
Query Neighborhood Hits	368	Target Neighborhood Hits	1069	Shared Neighborhood Hits	277
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DDEF2_HUMAN
NC score	0.330616 (rank : 274)	θ value	0.279714 (rank : 281)
Query Neighborhood Hits	368	Target Neighborhood Hits	599	Shared Neighborhood Hits	246
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TEX14_MOUSE
NC score	0.329023 (rank : 275)	θ value	0.000158464 (rank : 212)
Query Neighborhood Hits	368	Target Neighborhood Hits	1333	Shared Neighborhood Hits	280
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DDEF2_MOUSE
NC score	0.328191 (rank : 276)	θ value	0.279714 (rank : 282)
Query Neighborhood Hits	368	Target Neighborhood Hits	625	Shared Neighborhood Hits	249
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

TEX14_HUMAN
NC score	0.328023 (rank : 277)	θ value	1.43324e-05 (rank : 187)
Query Neighborhood Hits	368	Target Neighborhood Hits	1103	Shared Neighborhood Hits	249
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

DAPK1_MOUSE
NC score	0.316936 (rank : 278)	θ value	1.133e-10 (rank : 75)
Query Neighborhood Hits	368	Target Neighborhood Hits	1138	Shared Neighborhood Hits	286
SwissProt Accessions	Q80YE7, Q80YE6, Q8R341, Q8VDN6, Q9CSD4, Q9JJP7	Gene names	Dapk1
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

DGKZ_HUMAN
NC score	0.316564 (rank : 279)	θ value	0.00298849 (rank : 239)
Query Neighborhood Hits	368	Target Neighborhood Hits	551	Shared Neighborhood Hits	218
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DAPK1_HUMAN
NC score	0.310446 (rank : 280)	θ value	1.47974e-10 (rank : 76)
Query Neighborhood Hits	368	Target Neighborhood Hits	1130	Shared Neighborhood Hits	283
SwissProt Accessions	P53355, Q9BTL8	Gene names	DAPK1, DAPK
Domain Architecture
Description	Death-associated protein kinase 1 (EC 2.7.11.1) (DAP kinase 1).

CT012_HUMAN
NC score	0.308957 (rank : 281)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	368	Target Neighborhood Hits	205	Shared Neighborhood Hits	162
SwissProt Accessions	Q9NVP4, Q4F7X1, Q5QPD9, Q5QPE0, Q68DN8, Q6ZMX9, Q96NF0, Q9H1E0, Q9H442	Gene names	C20orf12
Domain Architecture
Description	Protein C20orf12.

DDFL1_HUMAN
NC score	0.299705 (rank : 282)	θ value	0.0961366 (rank : 271)
Query Neighborhood Hits	368	Target Neighborhood Hits	353	Shared Neighborhood Hits	231
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DGKZ_MOUSE
NC score	0.297604 (rank : 283)	θ value	0.0148317 (rank : 257)
Query Neighborhood Hits	368	Target Neighborhood Hits	542	Shared Neighborhood Hits	200
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

NOTC1_MOUSE
NC score	0.290722 (rank : 284)	θ value	9.92553e-07 (rank : 165)
Query Neighborhood Hits	368	Target Neighborhood Hits	916	Shared Neighborhood Hits	259
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

ANKZ1_MOUSE
NC score	0.283795 (rank : 285)	θ value	1.06291 (rank : 302)
Query Neighborhood Hits	368	Target Neighborhood Hits	208	Shared Neighborhood Hits	148
SwissProt Accessions	Q80UU1, Q9CZF5	Gene names	Ankzf1, D1Ertd161e
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1.

DGKI_HUMAN
NC score	0.283017 (rank : 286)	θ value	0.0330416 (rank : 259)
Query Neighborhood Hits	368	Target Neighborhood Hits	609	Shared Neighborhood Hits	213
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DDEF1_MOUSE
NC score	0.272842 (rank : 287)	θ value	0.0563607 (rank : 266)
Query Neighborhood Hits	368	Target Neighborhood Hits	592	Shared Neighborhood Hits	202
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

ANKZ1_HUMAN
NC score	0.270307 (rank : 288)	θ value	0.62314 (rank : 294)
Query Neighborhood Hits	368	Target Neighborhood Hits	236	Shared Neighborhood Hits	155
SwissProt Accessions	Q9H8Y5, Q9NVZ4	Gene names	ANKZF1, ZNF744
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744).

PKHA3_MOUSE
NC score	0.265955 (rank : 289)	θ value	0.00509761 (rank : 246)
Query Neighborhood Hits	368	Target Neighborhood Hits	67	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ERS4	Gene names	Plekha3, Fapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

CENG2_HUMAN
NC score	0.265914 (rank : 290)	θ value	0.47712 (rank : 291)
Query Neighborhood Hits	368	Target Neighborhood Hits	471	Shared Neighborhood Hits	248
SwissProt Accessions	Q9UPQ3, Q541S5, Q6P9D7, Q9NV93	Gene names	CENTG2, AGAP1, KIAA1099
Domain Architecture
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1) (GTP-binding and GTPase-activating protein 1) (GGAP1).

CENG1_MOUSE
NC score	0.265606 (rank : 291)	θ value	1.81305 (rank : 315)
Query Neighborhood Hits	368	Target Neighborhood Hits	531	Shared Neighborhood Hits	231
SwissProt Accessions	Q3UHD9, Q5DU45	Gene names	Centg1, Agap2, Kiaa0167
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE).

CENG2_MOUSE
NC score	0.264565 (rank : 292)	θ value	0.47712 (rank : 292)
Query Neighborhood Hits	368	Target Neighborhood Hits	463	Shared Neighborhood Hits	244
SwissProt Accessions	Q8BXK8, Q3UHA0, Q6ZPX9, Q8BZG0	Gene names	Centg2, Agap1, Kiaa1099
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 2 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 1) (AGAP-1).

CENG1_HUMAN
NC score	0.264131 (rank : 293)	θ value	3.0926 (rank : 325)
Query Neighborhood Hits	368	Target Neighborhood Hits	544	Shared Neighborhood Hits	234
SwissProt Accessions	Q99490, O00578, Q548E0, Q8IWU3	Gene names	CENTG1, AGAP2, KIAA0167
Domain Architecture
Description	Centaurin-gamma 1 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2) (AGAP-2) (Phosphatidylinositol-3-kinase enhancer) (PIKE) (GTP-binding and GTPase-activating protein 2) (GGAP2).

IKBL_HUMAN
NC score	0.260150 (rank : 294)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	368	Target Neighborhood Hits	168	Shared Neighborhood Hits	136
SwissProt Accessions	Q9UBC1, Q14625, Q9UBX4	Gene names	NFKBIL1, IKBL
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

CLR59_HUMAN
NC score	0.255416 (rank : 295)	θ value	0.163984 (rank : 277)
Query Neighborhood Hits	368	Target Neighborhood Hits	163	Shared Neighborhood Hits	141
SwissProt Accessions	Q96DZ5, Q8WWL1, Q96C99, Q9UFT7	Gene names	CLIPR59
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 170-related 59 kDa protein (CLIPR-59) (CLIP-170-related 59 kDa protein).

IKBL_MOUSE
NC score	0.253864 (rank : 296)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	368	Target Neighborhood Hits	196	Shared Neighborhood Hits	138
SwissProt Accessions	O88995, Q91X16, Q9R1Y3	Gene names	Nfkbil1, Ikbl
Domain Architecture
Description	NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like) (I- kappa-B-like) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1).

ABTB1_MOUSE
NC score	0.253742 (rank : 297)	θ value	0.813845 (rank : 297)
Query Neighborhood Hits	368	Target Neighborhood Hits	349	Shared Neighborhood Hits	177
SwissProt Accessions	Q99LJ2, Q8C2K7, Q91XU4	Gene names	Abtb1, Bpoz
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1.

PKHA3_HUMAN
NC score	0.251980 (rank : 298)	θ value	0.0961366 (rank : 272)
Query Neighborhood Hits	368	Target Neighborhood Hits	66	Shared Neighborhood Hits	20
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

C43BP_HUMAN
NC score	0.243942 (rank : 299)	θ value	9.29e-05 (rank : 201)
Query Neighborhood Hits	368	Target Neighborhood Hits	87	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y5P4, Q96Q85, Q96Q88, Q9H2S7, Q9H2S8	Gene names	COL4A3BP, STARD11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

ANKR9_MOUSE
NC score	0.241833 (rank : 300)	θ value	1.38821 (rank : 308)
Query Neighborhood Hits	368	Target Neighborhood Hits	120	Shared Neighborhood Hits	115
SwissProt Accessions	Q8BH83, Q3TA09, Q8BHR3	Gene names	Ankrd9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

BAT4_MOUSE
NC score	0.241769 (rank : 301)	θ value	0.125558 (rank : 273)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	119
SwissProt Accessions	Q61858, Q9R065	Gene names	Bat4, Bat-4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

C43BP_MOUSE
NC score	0.240001 (rank : 302)	θ value	0.000121331 (rank : 207)
Query Neighborhood Hits	368	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQG9, Q91WB1, Q9CU52, Q9EQG8	Gene names	Col4a3bp, Stard11
Domain Architecture
Description	Goodpasture antigen-binding protein (EC 2.7.11.9) (GPBP) (Collagen type IV alpha-3-binding protein) (StAR-related lipid transfer protein 11) (StARD11) (START domain-containing protein 11).

CENG3_HUMAN
NC score	0.237131 (rank : 303)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	368	Target Neighborhood Hits	455	Shared Neighborhood Hits	228
SwissProt Accessions	Q96P47, Q59EN0, Q96RK3	Gene names	CENTG3, AGAP3
Domain Architecture
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

CENG3_MOUSE
NC score	0.236829 (rank : 304)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	368	Target Neighborhood Hits	467	Shared Neighborhood Hits	230
SwissProt Accessions	Q8VHH5, Q812F7	Gene names	Centg3, Agap3
Domain Architecture	No domain graphic available
Description	Centaurin-gamma 3 (ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 3) (AGAP-3) (MR1-interacting protein) (MRIP-1) (CRAM-associated GTPase) (CRAG).

ABTB1_HUMAN
NC score	0.222069 (rank : 305)	θ value	1.81305 (rank : 313)
Query Neighborhood Hits	368	Target Neighborhood Hits	325	Shared Neighborhood Hits	161
SwissProt Accessions	Q969K4, Q6ZNU9, Q71MF1, Q96S62, Q96S63	Gene names	ABTB1, BPOZ
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and BTB/POZ domain-containing protein 1 (Elongation factor 1A-binding protein).

RSNL2_HUMAN
NC score	0.218420 (rank : 306)	θ value	0.0330416 (rank : 261)
Query Neighborhood Hits	368	Target Neighborhood Hits	136	Shared Neighborhood Hits	116
SwissProt Accessions	Q8N3C7, Q7Z4U3, Q96BR7, Q96MA5, Q9H7C0	Gene names	RSNL2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

BAT4_HUMAN
NC score	0.218315 (rank : 307)	θ value	0.279714 (rank : 280)
Query Neighborhood Hits	368	Target Neighborhood Hits	157	Shared Neighborhood Hits	110
SwissProt Accessions	O95872	Gene names	BAT4, G5
Domain Architecture
Description	Protein BAT4 (HLA-B-associated transcript 4) (G5 protein).

ANKR9_HUMAN
NC score	0.200427 (rank : 308)	θ value	1.38821 (rank : 307)
Query Neighborhood Hits	368	Target Neighborhood Hits	99	Shared Neighborhood Hits	96
SwissProt Accessions	Q96BM1	Gene names	ANKRD9
Domain Architecture
Description	Ankyrin repeat domain-containing protein 9.

TRPV3_MOUSE
NC score	0.195421 (rank : 309)	θ value	0.00175202 (rank : 238)
Query Neighborhood Hits	368	Target Neighborhood Hits	188	Shared Neighborhood Hits	124
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV3_HUMAN
NC score	0.191682 (rank : 310)	θ value	0.00665767 (rank : 249)
Query Neighborhood Hits	368	Target Neighborhood Hits	198	Shared Neighborhood Hits	135
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

RSNL2_MOUSE
NC score	0.188298 (rank : 311)	θ value	0.365318 (rank : 288)
Query Neighborhood Hits	368	Target Neighborhood Hits	129	Shared Neighborhood Hits	98
SwissProt Accessions	Q8CI96, Q8BW09, Q921Q4, Q9D2S6	Gene names	Rsnl2
Domain Architecture	No domain graphic available
Description	Restin-like protein 2.

TRPV1_MOUSE
NC score	0.176469 (rank : 312)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	368	Target Neighborhood Hits	189	Shared Neighborhood Hits	146
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV1_HUMAN
NC score	0.165330 (rank : 313)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	368	Target Neighborhood Hits	184	Shared Neighborhood Hits	138
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV2_HUMAN
NC score	0.152590 (rank : 314)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	368	Target Neighborhood Hits	130	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

CMTA1_HUMAN
NC score	0.138722 (rank : 315)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	368	Target Neighborhood Hits	217	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y6Y1, Q5VUE1	Gene names	CAMTA1, KIAA0833
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 1.

TRPV2_MOUSE
NC score	0.116035 (rank : 316)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	368	Target Neighborhood Hits	111	Shared Neighborhood Hits	87
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

CMTA2_HUMAN
NC score	0.109780 (rank : 317)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	368	Target Neighborhood Hits	199	Shared Neighborhood Hits	85
SwissProt Accessions	O94983, Q7Z6M8, Q8N3V0, Q8NDG4, Q96G17	Gene names	CAMTA2, KIAA0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

ANKF1_HUMAN
NC score	0.103223 (rank : 318)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	368	Target Neighborhood Hits	126	Shared Neighborhood Hits	67
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CMTA2_MOUSE
NC score	0.099642 (rank : 319)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	368	Target Neighborhood Hits	216	Shared Neighborhood Hits	73
SwissProt Accessions	Q80Y50, Q3TFK0, Q5SX68, Q80TP1, Q8R0D9, Q8R2N5	Gene names	Camta2, Kiaa0909
Domain Architecture	No domain graphic available
Description	Calmodulin-binding transcription activator 2.

TRPV4_HUMAN
NC score	0.086825 (rank : 320)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	368	Target Neighborhood Hits	150	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC6_HUMAN
NC score	0.082396 (rank : 321)	θ value	4.03905 (rank : 337)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	101
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPV4_MOUSE
NC score	0.079047 (rank : 322)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	368	Target Neighborhood Hits	117	Shared Neighborhood Hits	71
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

SWP70_HUMAN
NC score	0.078989 (rank : 323)	θ value	0.00298849 (rank : 240)
Query Neighborhood Hits	368	Target Neighborhood Hits	973	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SWP70_MOUSE
NC score	0.076381 (rank : 324)	θ value	0.0113563 (rank : 256)
Query Neighborhood Hits	368	Target Neighborhood Hits	1097	Shared Neighborhood Hits	82
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CU081_HUMAN
NC score	0.071635 (rank : 325)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	368	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NFU9	Gene names	C21orf81
Domain Architecture	No domain graphic available
Description	Protein C21orf81.

TRPC3_HUMAN
NC score	0.063893 (rank : 326)	θ value	6.88961 (rank : 357)
Query Neighborhood Hits	368	Target Neighborhood Hits	137	Shared Neighborhood Hits	78
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

LRRK1_MOUSE
NC score	0.062519 (rank : 327)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	368	Target Neighborhood Hits	1267	Shared Neighborhood Hits	126
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

TRPC3_MOUSE
NC score	0.058024 (rank : 328)	θ value	6.88961 (rank : 358)
Query Neighborhood Hits	368	Target Neighborhood Hits	131	Shared Neighborhood Hits	75
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC6_MOUSE
NC score	0.057261 (rank : 329)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	368	Target Neighborhood Hits	171	Shared Neighborhood Hits	86
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

REL_MOUSE
NC score	0.052000 (rank : 330)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	368	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	P15307	Gene names	Rel
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

REL_HUMAN
NC score	0.051631 (rank : 331)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	368	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q04864, Q2PNZ7, Q6LDY0	Gene names	REL
Domain Architecture
Description	C-Rel proto-oncogene protein (C-Rel protein).

TRPC7_MOUSE
NC score	0.050787 (rank : 332)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	368	Target Neighborhood Hits	114	Shared Neighborhood Hits	68
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.050778 (rank : 333)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	368	Target Neighborhood Hits	123	Shared Neighborhood Hits	69
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

RELB_MOUSE
NC score	0.050675 (rank : 334)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	368	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q04863	Gene names	Relb
Domain Architecture
Description	Transcription factor RelB.

RELB_HUMAN
NC score	0.050640 (rank : 335)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	368	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q01201, Q6GTX7, Q9UEI7	Gene names	RELB
Domain Architecture
Description	Transcription factor RelB (I-Rel).

TF65_MOUSE
NC score	0.050217 (rank : 336)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	368	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	Q04207, Q62025	Gene names	Rela, Nfkb3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

TRIPB_HUMAN
NC score	0.037282 (rank : 337)	θ value	0.813845 (rank : 301)
Query Neighborhood Hits	368	Target Neighborhood Hits	1587	Shared Neighborhood Hits	86
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

REST_HUMAN
NC score	0.035393 (rank : 338)	θ value	5.27518 (rank : 342)
Query Neighborhood Hits	368	Target Neighborhood Hits	1605	Shared Neighborhood Hits	80
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

GOGB1_HUMAN
NC score	0.035228 (rank : 339)	θ value	6.88961 (rank : 347)
Query Neighborhood Hits	368	Target Neighborhood Hits	2297	Shared Neighborhood Hits	95
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

REST_MOUSE
NC score	0.034423 (rank : 340)	θ value	1.06291 (rank : 305)
Query Neighborhood Hits	368	Target Neighborhood Hits	1506	Shared Neighborhood Hits	84
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

EP15R_MOUSE
NC score	0.034267 (rank : 341)	θ value	0.365318 (rank : 286)
Query Neighborhood Hits	368	Target Neighborhood Hits	1135	Shared Neighborhood Hits	72
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

PININ_MOUSE
NC score	0.033371 (rank : 342)	θ value	8.99809 (rank : 367)
Query Neighborhood Hits	368	Target Neighborhood Hits	777	Shared Neighborhood Hits	57
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

DESP_HUMAN
NC score	0.033050 (rank : 343)	θ value	3.0926 (rank : 327)
Query Neighborhood Hits	368	Target Neighborhood Hits	1470	Shared Neighborhood Hits	77
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

SYCP1_MOUSE
NC score	0.033029 (rank : 344)	θ value	8.99809 (rank : 368)
Query Neighborhood Hits	368	Target Neighborhood Hits	1456	Shared Neighborhood Hits	82
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

EP15R_HUMAN
NC score	0.032601 (rank : 345)	θ value	0.279714 (rank : 283)
Query Neighborhood Hits	368	Target Neighborhood Hits	1083	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

HMMR_MOUSE
NC score	0.032276 (rank : 346)	θ value	4.03905 (rank : 333)
Query Neighborhood Hits	368	Target Neighborhood Hits	1178	Shared Neighborhood Hits	69
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

BPAEA_MOUSE
NC score	0.031677 (rank : 347)	θ value	0.365318 (rank : 284)
Query Neighborhood Hits	368	Target Neighborhood Hits	1480	Shared Neighborhood Hits	73
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

EEA1_MOUSE
NC score	0.031199 (rank : 348)	θ value	5.27518 (rank : 340)
Query Neighborhood Hits	368	Target Neighborhood Hits	1637	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GOGA5_MOUSE
NC score	0.030780 (rank : 349)	θ value	1.81305 (rank : 317)
Query Neighborhood Hits	368	Target Neighborhood Hits	1434	Shared Neighborhood Hits	76
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CENPF_HUMAN
NC score	0.029985 (rank : 350)	θ value	3.0926 (rank : 326)
Query Neighborhood Hits	368	Target Neighborhood Hits	1932	Shared Neighborhood Hits	87
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

TS101_HUMAN
NC score	0.028327 (rank : 351)	θ value	1.38821 (rank : 311)
Query Neighborhood Hits	368	Target Neighborhood Hits	359	Shared Neighborhood Hits	33
SwissProt Accessions	Q99816, Q9BUM5	Gene names	TSG101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

DIAP1_MOUSE
NC score	0.027971 (rank : 352)	θ value	0.47712 (rank : 293)
Query Neighborhood Hits	368	Target Neighborhood Hits	839	Shared Neighborhood Hits	56
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

TS101_MOUSE
NC score	0.027617 (rank : 353)	θ value	1.38821 (rank : 312)
Query Neighborhood Hits	368	Target Neighborhood Hits	312	Shared Neighborhood Hits	31
SwissProt Accessions	Q61187	Gene names	Tsg101
Domain Architecture
Description	Tumor susceptibility gene 101 protein.

T3JAM_HUMAN
NC score	0.026678 (rank : 354)	θ value	4.03905 (rank : 336)
Query Neighborhood Hits	368	Target Neighborhood Hits	533	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CENPE_HUMAN
NC score	0.026364 (rank : 355)	θ value	5.27518 (rank : 339)
Query Neighborhood Hits	368	Target Neighborhood Hits	2060	Shared Neighborhood Hits	90
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MACF4_HUMAN
NC score	0.025060 (rank : 356)	θ value	1.81305 (rank : 320)
Query Neighborhood Hits	368	Target Neighborhood Hits	1321	Shared Neighborhood Hits	66
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

DIAP1_HUMAN
NC score	0.024534 (rank : 357)	θ value	0.813845 (rank : 298)
Query Neighborhood Hits	368	Target Neighborhood Hits	784	Shared Neighborhood Hits	48
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

SYNE1_HUMAN
NC score	0.023473 (rank : 358)	θ value	1.06291 (rank : 306)
Query Neighborhood Hits	368	Target Neighborhood Hits	1484	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

MACF1_HUMAN
NC score	0.021698 (rank : 359)	θ value	1.81305 (rank : 319)
Query Neighborhood Hits	368	Target Neighborhood Hits	1341	Shared Neighborhood Hits	64
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MYH6_MOUSE
NC score	0.021666 (rank : 360)	θ value	6.88961 (rank : 354)
Query Neighborhood Hits	368	Target Neighborhood Hits	1501	Shared Neighborhood Hits	80
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH13_HUMAN
NC score	0.021625 (rank : 361)	θ value	0.125558 (rank : 275)
Query Neighborhood Hits	368	Target Neighborhood Hits	1504	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH6_HUMAN
NC score	0.021620 (rank : 362)	θ value	6.88961 (rank : 353)
Query Neighborhood Hits	368	Target Neighborhood Hits	1426	Shared Neighborhood Hits	80
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH8_HUMAN
NC score	0.021192 (rank : 363)	θ value	3.0926 (rank : 328)
Query Neighborhood Hits	368	Target Neighborhood Hits	1610	Shared Neighborhood Hits	82
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

LRP1B_HUMAN
NC score	0.020769 (rank : 364)	θ value	6.88961 (rank : 350)
Query Neighborhood Hits	368	Target Neighborhood Hits	602	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
NC score	0.019937 (rank : 365)	θ value	8.99809 (rank : 363)
Query Neighborhood Hits	368	Target Neighborhood Hits	606	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

SPTA2_HUMAN
NC score	0.019487 (rank : 366)	θ value	4.03905 (rank : 335)
Query Neighborhood Hits	368	Target Neighborhood Hits	888	Shared Neighborhood Hits	60
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

ROCK1_MOUSE
NC score	0.018635 (rank : 367)	θ value	5.27518 (rank : 343)
Query Neighborhood Hits	368	Target Neighborhood Hits	2126	Shared Neighborhood Hits	85
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

HSF2_HUMAN
NC score	0.017228 (rank : 368)	θ value	1.06291 (rank : 303)
Query Neighborhood Hits	368	Target Neighborhood Hits	149	Shared Neighborhood Hits	18
SwissProt Accessions	Q03933, Q9H445	Gene names	HSF2, HSTF2
Domain Architecture
Description	Heat shock factor protein 2 (HSF 2) (Heat shock transcription factor 2) (HSTF 2).

FYB_HUMAN
NC score	0.016220 (rank : 369)	θ value	5.27518 (rank : 341)
Query Neighborhood Hits	368	Target Neighborhood Hits	379	Shared Neighborhood Hits	15
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MRCKA_HUMAN
NC score	0.014941 (rank : 370)	θ value	0.62314 (rank : 296)
Query Neighborhood Hits	368	Target Neighborhood Hits	1999	Shared Neighborhood Hits	79
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

ARHG7_MOUSE
NC score	0.013985 (rank : 371)	θ value	5.27518 (rank : 338)
Query Neighborhood Hits	368	Target Neighborhood Hits	396	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

RL21_HUMAN
NC score	0.013806 (rank : 372)	θ value	2.36792 (rank : 324)
Query Neighborhood Hits	368	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	P46778, Q16699	Gene names	RPL21
Domain Architecture
Description	60S ribosomal protein L21.

LIGA_HUMAN
NC score	0.013332 (rank : 373)	θ value	1.81305 (rank : 318)
Query Neighborhood Hits	368	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P41214, Q9NR27, Q9NSN0, Q9NV18, Q9NZ21	Gene names	LGTN, HCA56
Domain Architecture
Description	Ligatin (Hepatocellular carcinoma-associated antigen 56).

KI21A_MOUSE
NC score	0.013298 (rank : 374)	θ value	6.88961 (rank : 349)
Query Neighborhood Hits	368	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

OCLN_HUMAN
NC score	0.012876 (rank : 375)	θ value	8.99809 (rank : 365)
Query Neighborhood Hits	368	Target Neighborhood Hits	131	Shared Neighborhood Hits	19
SwissProt Accessions	Q16625, Q8N6K1	Gene names	OCLN
Domain Architecture
Description	Occludin.

PRGC2_MOUSE
NC score	0.012364 (rank : 376)	θ value	2.36792 (rank : 323)
Query Neighborhood Hits	368	Target Neighborhood Hits	225	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHJ7, Q8C1C0	Gene names	Ppargc1b, Errl1, Pgc1, Pgc1b, Ppargc1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta protein) (PGC-1beta) (ERR ligand 1) (PPARGC-1-beta) (PGC-1-beta).

PACN2_HUMAN
NC score	0.012085 (rank : 377)	θ value	8.99809 (rank : 366)
Query Neighborhood Hits	368	Target Neighborhood Hits	339	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UNF0, O95921, Q96HV9, Q9H0D3, Q9NPN1, Q9Y4V2	Gene names	PACSIN2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN2_MOUSE
NC score	0.012063 (rank : 378)	θ value	6.88961 (rank : 355)
Query Neighborhood Hits	368	Target Neighborhood Hits	382	Shared Neighborhood Hits	31
SwissProt Accessions	Q9WVE8	Gene names	Pacsin2
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 2.

PACN3_HUMAN
NC score	0.011305 (rank : 379)	θ value	4.03905 (rank : 334)
Query Neighborhood Hits	368	Target Neighborhood Hits	385	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UKS6, Q9H331, Q9NWV9	Gene names	PACSIN3
Domain Architecture
Description	Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) (Endophilin I).

CEP68_HUMAN
NC score	0.010981 (rank : 380)	θ value	4.03905 (rank : 331)
Query Neighborhood Hits	368	Target Neighborhood Hits	128	Shared Neighborhood Hits	10
SwissProt Accessions	Q76N32, O60326, Q9BQ18, Q9UDM9	Gene names	CEP68, KIAA0582
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 68 kDa (Cep68 protein).

FYB_MOUSE
NC score	0.010720 (rank : 381)	θ value	6.88961 (rank : 346)
Query Neighborhood Hits	368	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	O35601, Q9Z2H3	Gene names	Fyb
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

SPTB1_HUMAN
NC score	0.010190 (rank : 382)	θ value	6.88961 (rank : 356)
Query Neighborhood Hits	368	Target Neighborhood Hits	541	Shared Neighborhood Hits	48
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

RAE2_MOUSE
NC score	0.010124 (rank : 383)	θ value	1.06291 (rank : 304)
Query Neighborhood Hits	368	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZD5, Q8CH16	Gene names	Chml, Rep2
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 2 (Rab escort protein 2) (REP-2) (Choroideraemia-like protein).

DFFA_HUMAN
NC score	0.009618 (rank : 384)	θ value	8.99809 (rank : 361)
Query Neighborhood Hits	368	Target Neighborhood Hits	118	Shared Neighborhood Hits	19
SwissProt Accessions	O00273, Q96I97, Q9Y6C6	Gene names	DFFA, DFF1, DFF45
Domain Architecture	No domain graphic available
Description	DNA fragmentation factor subunit alpha (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) (ICAD).

KLC1_MOUSE
NC score	0.008975 (rank : 385)	θ value	8.99809 (rank : 362)
Query Neighborhood Hits	368	Target Neighborhood Hits	357	Shared Neighborhood Hits	38
SwissProt Accessions	O88447	Gene names	Kns2, Klc1
Domain Architecture	No domain graphic available
Description	Kinesin light chain 1 (KLC 1).

M4K4_HUMAN
NC score	0.008285 (rank : 386)	θ value	2.36792 (rank : 321)
Query Neighborhood Hits	368	Target Neighborhood Hits	1589	Shared Neighborhood Hits	68
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MORC1_HUMAN
NC score	0.008119 (rank : 387)	θ value	8.99809 (rank : 364)
Query Neighborhood Hits	368	Target Neighborhood Hits	127	Shared Neighborhood Hits	19
SwissProt Accessions	Q86VD1, Q7L8E2, Q9NSG7, Q9Y6D4	Gene names	MORC1, MORC
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 1.

M4K4_MOUSE
NC score	0.008097 (rank : 388)	θ value	2.36792 (rank : 322)
Query Neighborhood Hits	368	Target Neighborhood Hits	1560	Shared Neighborhood Hits	63
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

CELR1_HUMAN
NC score	0.007834 (rank : 389)	θ value	4.03905 (rank : 330)
Query Neighborhood Hits	368	Target Neighborhood Hits	613	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

DPOLZ_HUMAN
NC score	0.006968 (rank : 390)	θ value	4.03905 (rank : 332)
Query Neighborhood Hits	368	Target Neighborhood Hits	200	Shared Neighborhood Hits	11
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

ELOA2_HUMAN
NC score	0.004363 (rank : 391)	θ value	6.88961 (rank : 345)
Query Neighborhood Hits	368	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IYF1, Q9P2V9	Gene names	TCEB3B, TCEB3L
Domain Architecture
Description	RNA polymerase II transcription factor SIII subunit A2 (Elongin-A2) (EloA2) (Transcription elongation factor B polypeptide 3B).

MINK1_MOUSE
NC score	0.003874 (rank : 392)	θ value	6.88961 (rank : 352)
Query Neighborhood Hits	368	Target Neighborhood Hits	1451	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JM52, Q921M6, Q9JM92	Gene names	Mink1, Map4k6, Mink
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

MINK1_HUMAN
NC score	0.003461 (rank : 393)	θ value	6.88961 (rank : 351)
Query Neighborhood Hits	368	Target Neighborhood Hits	1477	Shared Neighborhood Hits	56
SwissProt Accessions	Q8N4C8, Q9P1X1, Q9P2R8	Gene names	MINK1, MAP4K6, MINK
Domain Architecture
Description	Misshapen-like kinase 1 (EC 2.7.11.1) (Mitogen-activated protein kinase kinase kinase kinase 6) (MAPK/ERK kinase kinase kinase 6) (MEK kinase kinase 6) (MEKKK 6) (Misshapen/NIK-related kinase) (GCK family kinase MiNK).

PRP4_MOUSE
NC score	0.003229 (rank : 394)	θ value	0.813845 (rank : 300)
Query Neighborhood Hits	368	Target Neighborhood Hits	308	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DAW6	Gene names	Prpf4
Domain Architecture	No domain graphic available
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4).

PRP4_HUMAN
NC score	0.003164 (rank : 395)	θ value	0.813845 (rank : 299)
Query Neighborhood Hits	368	Target Neighborhood Hits	309	Shared Neighborhood Hits	5
SwissProt Accessions	O43172, O43445, O43864, Q96DG2, Q96IK4	Gene names	PRPF4, PRP4
Domain Architecture
Description	U4/U6 small nuclear ribonucleoprotein Prp4 (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) (hPrp4).

IFIH1_MOUSE
NC score	0.001395 (rank : 396)	θ value	6.88961 (rank : 348)
Query Neighborhood Hits	368	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q8R5F7, Q3U6S2, Q68EM4, Q8BYC9, Q8BZ01, Q8K5C7, Q8R144, Q8VE79, Q99KS4, Q9D2Z5	Gene names	Ifih1
Domain Architecture	No domain graphic available
Description	Interferon-induced helicase C domain-containing protein 1 (EC 3.6.1.-) (Interferon induced with helicase C domain protein 1) (Helicase with 2 CARD domains) (Helicard) (Melanoma differentiation-associated protein 5) (MDA-5).

ABCC9_MOUSE
NC score	-0.002195 (rank : 397)	θ value	8.99809 (rank : 359)
Query Neighborhood Hits	368	Target Neighborhood Hits	110	Shared Neighborhood Hits	3
SwissProt Accessions	P70170, O08902, O08920, P70171	Gene names	Abcc9, Sur2
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 9 (Sulfonylurea receptor 2).